hydrochlorothiazide has been researched along with Cardiac Remodeling, Ventricular in 8 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our previous study indicates that hydrochlorothiazide inhibits transforming growth factor (TGF)-β/Smad signaling pathway, improves cardiac function and reduces fibrosis." | 7.85 | Hydrochlorothiazide modulates ischemic heart failure-induced cardiac remodeling via inhibiting angiotensin II type 1 receptor pathway in rats. ( Chen, X; Gao, X; Lu, G; Luo, C; Luo, J; Peng, L; Zuo, Z, 2017) |
| "Heart failure is a major cause of morbidity and mortality worldwide." | 5.37 | Effects of hydrochlorothiazide on cardiac remodeling in a rat model of myocardial infarction-induced congestive heart failure. ( Dai, G; Gao, X; Luo, J; Peng, L; Sun, H, 2011) |
| "The aim of this study was to evaluate the effect of the calcium antagonist Nifedipine GITS in a double-blind, randomized comparison with the diuretic hydrochlorothiazide (HCTZ) on reduction of left ventricular (LV) mass and minimal vascular resistance in a group of essential hypertensives with left ventricular hypertrophy (LVH)." | 5.08 | Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients. ( Agabiti-Rosei, E; Corbellini, C; Monteduro, C; Muiesan, ML; Rizzoni, D; Salvetti, M; Zulli, R, 1998) |
| "Our previous study indicates that hydrochlorothiazide inhibits transforming growth factor (TGF)-β/Smad signaling pathway, improves cardiac function and reduces fibrosis." | 3.85 | Hydrochlorothiazide modulates ischemic heart failure-induced cardiac remodeling via inhibiting angiotensin II type 1 receptor pathway in rats. ( Chen, X; Gao, X; Lu, G; Luo, C; Luo, J; Peng, L; Zuo, Z, 2017) |
| "To investigate the effects of perindopril, propranolol, and dihydrochlorothiazide on artery wall thickening, left ventricular hypertrophy, and cardiac fibrosis in spontaneously hypertensive rats (SHR)." | 3.70 | Effects of perindopril, propranolol, and dihydrochlorothiazide on cardiovascular remodelling in spontaneously hypertensive rats. ( Chen, DG; Chen, SC; Rui, HB; Su, JZ; Wang, HJ; Wang, XY; Wu, KG, 1999) |
| "Heart failure is a major cause of morbidity and mortality worldwide." | 1.37 | Effects of hydrochlorothiazide on cardiac remodeling in a rat model of myocardial infarction-induced congestive heart failure. ( Dai, G; Gao, X; Luo, J; Peng, L; Sun, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, J | 2 |
| Chen, X | 1 |
| Luo, C | 1 |
| Lu, G | 1 |
| Peng, L | 2 |
| Gao, X | 2 |
| Zuo, Z | 1 |
| Tsareva, VM | 1 |
| Khoziainova, NIu | 1 |
| Sun, H | 1 |
| Dai, G | 1 |
| Mougenot, N | 1 |
| Médiani, O | 1 |
| Lechat, P | 1 |
| Boydak, B | 1 |
| Nalbantgil, S | 1 |
| Yilmaz, H | 1 |
| Zoghi, M | 1 |
| Ozerkan, F | 1 |
| Nalbantgil, I | 1 |
| Onder, R | 1 |
| Agabiti-Rosei, E | 1 |
| Zulli, R | 1 |
| Muiesan, ML | 1 |
| Salvetti, M | 1 |
| Rizzoni, D | 1 |
| Corbellini, C | 1 |
| Monteduro, C | 1 |
| Brilla, CG | 1 |
| Su, JZ | 1 |
| Chen, SC | 1 |
| Wu, KG | 1 |
| Chen, DG | 1 |
| Rui, HB | 1 |
| Wang, XY | 1 |
| Wang, HJ | 1 |
3 trials available for hydrochlorothiazide and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
[The role of combination therapy in the treatment of arterial hypertension].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; Drug C | 2009 |
The effect of combination therapy on regression of left ventricular hypertrophy in cases with hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Ch | 2004 |
Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Prepa | 1998 |
5 other studies available for hydrochlorothiazide and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Hydrochlorothiazide modulates ischemic heart failure-induced cardiac remodeling via inhibiting angiotensin II type 1 receptor pathway in rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cel | 2017 |
Effects of hydrochlorothiazide on cardiac remodeling in a rat model of myocardial infarction-induced congestive heart failure.
Topics: Animals; Collagen; Cytokines; Disease Models, Animal; Electrolytes; Gene Expression Regulation; Hear | 2011 |
Bisoprolol and hydrochlorothiazide effects on cardiovascular remodeling in spontaneously hypertensive rats.
Topics: Animals; Bisoprolol; Cardiovascular Agents; Dose-Response Relationship, Drug; Drug Synergism; Drug T | 2005 |
Renin-angiotensin system mediated mechanisms: cardioreparation and cardioprotection.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diuretics; Female; Fibrosis; Heart Failure; Human | 2000 |
Effects of perindopril, propranolol, and dihydrochlorothiazide on cardiovascular remodelling in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Age | 1999 |