hydrochlorothiazide has been researched along with Cardiac Complex, Premature in 18 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirteen patients developed syncope and a prolonged QTc interval while taking therapeutic doses of sotalol." | 7.67 | Sotalol, hypokalaemia, syncope, and torsade de pointes. ( Barlow, JB; McKibbin, JK; Millar, RN; Obel, IW; Pocock, WA, 1984) |
| "Forty-four patients with uncomplicated systemic hypertension underwent 48-hour electrocardiographic monitoring before and after four weeks of treatment with hydrochlorothiazide, 100 mg daily." | 5.06 | Thiazide therapy is not a cause of arrhythmia in patients with systemic hypertension. ( Burris, JF; Fletcher, RD; Freis, ED; Notargiacomo, A; Papademetriou, V, 1988) |
| "Thirteen patients developed syncope and a prolonged QTc interval while taking therapeutic doses of sotalol." | 3.67 | Sotalol, hypokalaemia, syncope, and torsade de pointes. ( Barlow, JB; McKibbin, JK; Millar, RN; Obel, IW; Pocock, WA, 1984) |
| " Thirty-one patients with uncomplicated hypertension underwent 48-hour ambulatory ECG monitoring both before any treatment and after 4 weeks of hydrochlorothiazide, (HCTZ), 100 mg daily." | 3.67 | Effect of diuretic therapy on ventricular arrhythmias in hypertensive patients with or without left ventricular hypertrophy. ( Fletcher, RD; Freis, ED; Gottdiener, J; Notargiacomo, A; Papademetriou, V; Price, M, 1985) |
| "Serious ventricular arrhythmias occurred in 13 of 37 patients receiving hydrochlorothiazide compared with 15 of 37 receiving placebo and 9 of 37 receiving hydrochlorothiazide + amiloride." | 2.67 | Diuretic therapy and ventricular arrhythmias in persons 65 years of age and older. ( Myers, MG, 1990) |
| "There was no difference in ventricular extrasystoles between the two supplementation groups." | 2.66 | The effect of potassium and potassium plus magnesium supplementation on ventricular extrasystoles in mild hypertensives treated with hydrochlorothiazide. ( Jounela, AJ; Lumme, JA, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (66.67) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Papademetriou, V | 5 |
| Fletcher, R | 1 |
| Khatri, IM | 1 |
| Freis, ED | 4 |
| McKibbin, JK | 1 |
| Pocock, WA | 1 |
| Barlow, JB | 1 |
| Millar, RN | 1 |
| Obel, IW | 1 |
| Narayan, P | 1 |
| Kokkinos, P | 1 |
| Lumme, JA | 2 |
| Jounela, AJ | 2 |
| Nordrehaug, JE | 1 |
| Vollset, SE | 1 |
| Sideris, DA | 3 |
| Toumanidis, ST | 1 |
| Anastasiou-Nana, M | 1 |
| Zakopoulos, N | 1 |
| Kitsiou, A | 1 |
| Tsagarakis, K | 1 |
| Moulopoulos, SD | 2 |
| Myers, MG | 1 |
| Seelig, CB | 1 |
| Price, M | 1 |
| Notargiacomo, A | 3 |
| Gottdiener, J | 1 |
| Fletcher, RD | 3 |
| DeQuattro, V | 1 |
| deGrau, A | 1 |
| Foti, A | 1 |
| Kim, SJ | 1 |
| DeQuattro, E | 1 |
| Allen, J | 1 |
| Kuller, LH | 1 |
| Hulley, SB | 1 |
| Cohen, JD | 1 |
| Neaton, J | 1 |
| Burris, JF | 1 |
| Krishna, GG | 1 |
| Narins, RG | 1 |
| Kontoyannis, DA | 1 |
| Diakos, A | 1 |
| Kontoyannis, SA | 1 |
| Heine, D | 1 |
| Roux, M | 1 |
| Herne, N | 1 |
| Gilly, R | 1 |
| Michaud, J | 1 |
| Le Gall, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000487] | Phase 3 | 0 participants | Interventional | 1972-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 trials available for hydrochlorothiazide and Cardiac Complex, Premature
| Article | Year |
|---|---|
Effects of diltiazem, metoprolol, enalapril and hydrochlorothiazide on frequency of ventricular premature complexes.
Topics: Analysis of Variance; Antihypertensive Agents; Cardiac Complexes, Premature; Diltiazem; Echocardiogr | 1994 |
Left ventricular mass, serum electrolyte levels and cardiac arrhythmias in patients with mild hypertension treated with cilazapril or hydrochlorothiazide.
Topics: Cardiac Complexes, Premature; Cilazapril; Double-Blind Method; Echocardiography; Electrocardiography | 1993 |
Reduction of exercise-induced ventricular arrhythmias in mild symptomatic heart failure by benazepril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiac Complexes, Premature; Double-Blind M | 1993 |
The circadian profile of extrasystolic arrhythmia: its relationship to heart rate and blood pressure.
Topics: Adult; Aged; Aged, 80 and over; Amiloride; Blood Pressure; Blood Pressure Monitors; Cardiac Complexe | 1992 |
Diuretic therapy and ventricular arrhythmias in persons 65 years of age and older.
Topics: Aged; Aged, 80 and over; Amiloride; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Double-Blind | 1990 |
Thiazide therapy is not a cause of arrhythmia in patients with systemic hypertension.
Topics: Cardiac Complexes, Premature; Cardiomegaly; Clinical Trials as Topic; Electrocardiography; Humans; H | 1988 |
The effect of potassium and potassium plus magnesium supplementation on ventricular extrasystoles in mild hypertensives treated with hydrochlorothiazide.
Topics: Adult; Aged; Blood Pressure; Cardiac Complexes, Premature; Double-Blind Method; Drug Therapy, Combin | 1989 |
Effects of diuretic therapy and exercise-related arrhythmias in systemic hypertension.
Topics: Blood Pressure; Cardiac Complexes, Premature; Catecholamines; Double-Blind Method; Electrocardiograp | 1989 |
10 other studies available for hydrochlorothiazide and Cardiac Complex, Premature
| Article | Year |
|---|---|
Diuretic-induced hypokalemia in uncomplicated systemic hypertension: effect of plasma potassium correction on cardiac arrhythmias.
Topics: Adult; Aged; Ambulatory Care; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiac Complexes, Prem | 1983 |
Sotalol, hypokalaemia, syncope, and torsade de pointes.
Topics: Adult; Aged; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Female; H | 1984 |
Magnesium deficiency in two hypertensive patient groups.
Topics: Antihypertensive Agents; Cardiac Complexes, Premature; Drug Evaluation; Female; Humans; Hydrochlorot | 1990 |
Effect of diuretic therapy on ventricular arrhythmias in hypertensive patients with or without left ventricular hypertrophy.
Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiomegaly; Diuretics; Echocardio | 1985 |
Effects of exercise on blood pressure, plasma catecholamines, potassium and the electrocardiogram after diuretic and neural-blocking therapy for moderate hypertension.
Topics: Blood Pressure; Cardiac Complexes, Premature; Catecholamines; Cholesterol; Drug Therapy, Combination | 1985 |
Unexpected effects of treating hypertension in men with electrocardiographic abnormalities: a critical analysis.
Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiomegaly; Catecholamines; Chlorthalid | 1986 |
The importance of blood pressure in the emergence of arrhythmias.
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Biomechanical Phenomena; Blood Pressure; Cardiac Complexes | 1987 |
Hemodynamic consequences of diuretic-induced hypokalemia.
Topics: Adult; Cardiac Complexes, Premature; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypoka | 1988 |
Antihypertensive treatment for the management of premature ventricular complexes. Pilot study.
Topics: Adult; Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure; Cardiac Complexe | 1988 |
[Clinical study of amiloride hydrochloride, a diuretic with low potassium loss].
Topics: Arrhythmias, Cardiac; Blood Urea Nitrogen; Cardiac Complexes, Premature; Diuretics; Drug Synergism; | 1970 |