hydrochlorothiazide has been researched along with Carcinoma, Merkel Cell in 1 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Carcinoma, Merkel Cell: A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrochlorothiazide use has been associated with markedly increased risk for squamous cell carcinoma." | 1.51 | Hydrochlorothiazide use and risk for Merkel cell carcinoma and malignant adnexal skin tumors: A nationwide case-control study. ( Friis, S; Gaist, D; Hölmich, LR; Johannesdottir Schmidt, SA; Pedersen, SA; Pottegård, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, SA | 1 |
| Johannesdottir Schmidt, SA | 1 |
| Hölmich, LR | 1 |
| Friis, S | 1 |
| Pottegård, A | 1 |
| Gaist, D | 1 |
1 other study available for hydrochlorothiazide and Carcinoma, Merkel Cell
| Article | Year |
|---|---|
Hydrochlorothiazide use and risk for Merkel cell carcinoma and malignant adnexal skin tumors: A nationwide case-control study.
Topics: Age Distribution; Aged; Aged, 80 and over; Carcinoma, Merkel Cell; Case-Control Studies; Denmark; Do | 2019 |