Page last updated: 2024-10-28

hydrochlorothiazide and Cancer of Lip

hydrochlorothiazide has been researched along with Cancer of Lip in 9 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"The antihypertensive agent hydrochlorothiazide has been associated with increased risks of non-melanoma skin cancer (NMSC) and possibly some melanoma subtypes."3.91Use of hydrochlorothiazide and risk of skin cancer: a nationwide Taiwanese case-control study. ( Hsu, CK; Lai, EC; Lee, CN; Liao, TC; Pedersen, SA; Pottegård, A; Schmidt, SAJ; Shao, SC, 2019)
"The mean age for cutaneous and lip squamous cell carcinoma development was 73."2.82Hydrochlorothiazide use is associated with the risk of cutaneous and lip squamous cell carcinoma: A systematic review and meta-analysis. ( Barboza, CAG; de Castro, RD; de Lisboa Lopes Costa, A; de Macedo Andrade, AC; Felix, FA; França, GM; Ribeiro, ILA, 2022)
"Patients within the lip cancer and oral cancer groups were accepted with a history of non-melanoma skin cancer (NMSC)."2.82Does hydrochlorothiazide increase the incidence of skin, lip and oral cancer in a UK population? ( Carney, K; Cousins, M, 2022)
"Hydrochlorothiazide exposure was associated with an increased risk of SCC, BCC and lip cancer that is not explained following adjustment for smoking and BMI."1.56Association between hydrochlorothiazide exposure and different incident skin, lip and oral cavity cancers: A series of population-based nested case-control studies. ( Kurz, X; Morales, DR; Pacurariu, A; Slattery, J, 2020)
" There was a clear dose-response effect (P < 0."1.46Hydrochlorothiazide use is strongly associated with risk of lip cancer. ( Friedman, GD; Friis, S; Habel, LA; Hallas, J; Olesen, M; Pottegård, A; Svendsen, MT, 2017)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (55.56)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
de Macedo Andrade, AC1
Felix, FA1
França, GM1
Ribeiro, ILA1
Barboza, CAG1
de Castro, RD1
de Lisboa Lopes Costa, A1
Carney, K1
Cousins, M1
Pottegård, A3
Pedersen, SA1
Schmidt, SAJ1
Lee, CN1
Hsu, CK1
Liao, TC1
Shao, SC1
Lai, EC1
Morales, DR1
Pacurariu, A1
Slattery, J1
Kurz, X1
Daniels, B1
Pearson, SA1
Vajdic, CM1
Buckley, NA1
Zoega, H1
Hallas, J1
Olesen, M1
Svendsen, MT1
Habel, LA2
Friedman, GD2
Friis, S1
Cognetta, AB1
Wolfe, CM1
Heinrichs, E1
Asgari, MM1
Warton, EM1
Chan, J1
Katz, MH1

Reviews

3 reviews available for hydrochlorothiazide and Cancer of Lip

ArticleYear
Hydrochlorothiazide use is associated with the risk of cutaneous and lip squamous cell carcinoma: A systematic review and meta-analysis.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:6

    Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Hydrochlorothiazide; Lip; Lip Neoplasms; Male; Skin

2022
Does hydrochlorothiazide increase the incidence of skin, lip and oral cancer in a UK population?
    Evidence-based dentistry, 2022, Volume: 23, Issue:1

    Topics: Adult; Carcinoma, Basal Cell; Humans; Hydrochlorothiazide; Incidence; Lip Neoplasms; Skin Neoplasms;

2022
Hydrochlorothiazide Use and Skin Cancer: A Mohs Surgeon's Concern.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2016, Volume: 42, Issue:9

    Topics: Antihypertensive Agents; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Hydrochlorothiazid

2016

Other Studies

6 other studies available for hydrochlorothiazide and Cancer of Lip

ArticleYear
Use of hydrochlorothiazide and risk of skin cancer: a nationwide Taiwanese case-control study.
    British journal of cancer, 2019, Volume: 121, Issue:11

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Case-Control Studies; Female; Humans; Hydrochlorot

2019
Association between hydrochlorothiazide exposure and different incident skin, lip and oral cavity cancers: A series of population-based nested case-control studies.
    British journal of clinical pharmacology, 2020, Volume: 86, Issue:7

    Topics: Adult; Carcinoma, Basal Cell; Case-Control Studies; Humans; Hydrochlorothiazide; Incidence; Lip Neop

2020
Risk of squamous cell carcinoma of the lip and cutaneous melanoma in older Australians using hydrochlorothiazide: A population-based case-control study.
    Basic & clinical pharmacology & toxicology, 2020, Volume: 127, Issue:4

    Topics: Aged; Aged, 80 and over; Australia; Carcinoma, Squamous Cell; Case-Control Studies; Cohort Studies;

2020
Hydrochlorothiazide use is strongly associated with risk of lip cancer.
    Journal of internal medicine, 2017, Volume: 282, Issue:4

    Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Case-Control Studies; Denmark; Diuretics; Dose-Re

2017
Antihypertensive drugs and lip cancer in non-Hispanic whites.
    Archives of internal medicine, 2012, Sep-10, Volume: 172, Issue:16

    Topics: Adult; Aged; Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Hypertension; Lip Neoplas

2012
Sun protection for all: but especially for those receiving certain hypertensive medications: comment on "Antihypertensive drugs and lip cancer in non-Hispanic whites".
    Archives of internal medicine, 2012, Sep-10, Volume: 172, Issue:16

    Topics: Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Lip Neoplasms; Male; Nifedipine; White

2012