hydrochlorothiazide has been researched along with Bronchopulmonary Dysplasia in 4 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Bronchopulmonary Dysplasia: A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that spironolactone-hydrochlorothiazide (Aldactazide) will improve urine output and lung function in infants with bronchopulmonary dysplasia, we studied 21 hospitalized, spontaneously breathing, oxygen-dependent infants with chronic bronchopulmonary dysplasia." | 9.06 | Effect of spironolactone-hydrochlorothiazide on lung function in infants with chronic bronchopulmonary dysplasia. ( Blalock, WA; DonLevy, S; Engelhardt, B; Hazinski, TA; Rush, M, 1989) |
| "The effects of continuous therapy with hydrochlorothiazide and spironolactone on pulmonary function in 34 premature infants with severe bronchopulmonary dysplasia were assessed in a randomized double-blind controlled trial." | 5.06 | Randomized, double-blind, controlled trial of long-term diuretic therapy for bronchopulmonary dysplasia. ( Albersheim, SG; Rotschild, A; Sharma, AK; Sheps, SB; Smyth, JA; Solimano, AJ; Wood, BJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laughon, MM | 1 |
| Chantala, K | 1 |
| Aliaga, S | 1 |
| Herring, AH | 1 |
| Hornik, CP | 1 |
| Hughes, R | 1 |
| Clark, RH | 1 |
| Smith, PB | 1 |
| Abman, SH | 1 |
| Warady, BA | 1 |
| Lum, GM | 1 |
| Koops, BL | 1 |
| Albersheim, SG | 1 |
| Solimano, AJ | 1 |
| Sharma, AK | 1 |
| Smyth, JA | 1 |
| Rotschild, A | 1 |
| Wood, BJ | 1 |
| Sheps, SB | 1 |
| Engelhardt, B | 1 |
| Blalock, WA | 1 |
| DonLevy, S | 1 |
| Rush, M | 1 |
| Hazinski, TA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease[NCT01721655] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2012-10-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for hydrochlorothiazide and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Randomized, double-blind, controlled trial of long-term diuretic therapy for bronchopulmonary dysplasia.
Topics: Bronchopulmonary Dysplasia; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studie | 1989 |
Effect of spironolactone-hydrochlorothiazide on lung function in infants with chronic bronchopulmonary dysplasia.
Topics: Bronchopulmonary Dysplasia; Drug Combinations; Hemoglobins; Humans; Hydrochlorothiazide; Infant; Inf | 1989 |
2 other studies available for hydrochlorothiazide and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Diuretic exposure in premature infants from 1997 to 2011.
Topics: Acetazolamide; Amiloride; Bronchopulmonary Dysplasia; Chlorothiazide; Cohort Studies; Diazoxide; Diu | 2015 |
Systemic hypertension in infants with bronchopulmonary dysplasia.
Topics: Bronchopulmonary Dysplasia; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Infant; In | 1984 |