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hydrochlorothiazide and Bipolar Disorder

hydrochlorothiazide has been researched along with Bipolar Disorder in 9 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Two patients on long-term lithium therapy for manic-depressive psychosis developed serious toxicity within days of being prescribed a combination of triamterene (50 mg) and hydrochlorothiazide (25 mg) for mild symptomless hypertension."3.66Lithium toxicity induced by triamterene-hydrochlorothiazide. ( Mehta, BR; Robinson, BH, 1980)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Handler, J1
Mehta, BR1
Robinson, BH1
Voegeli, J1
Baumann, P1
Haynes, WF1
Elmore, JL1
Maletzky, BM1
Krulík, R1
Farská, I1
Prokes, J1
König, P1
Küfferle, B1
Lenz, G1
Nurnberger, JI1
Shopsin, B1
Gershon, S1

Trials

2 trials available for hydrochlorothiazide and Bipolar Disorder

ArticleYear
Enhancing the efficacy of lithium treatment by combined use with diuretics and low sodium diets: a preliminary report.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:7

    Topics: Adolescent; Adult; Bipolar Disorder; Clinical Trials as Topic; Diet, Sodium-Restricted; Drug Therapy

1979
The current status of lithium in psychiatry.
    The American journal of the medical sciences, 1974, Volume: 268, Issue:6

    Topics: Acute Disease; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Female; Halop

1974

Other Studies

7 other studies available for hydrochlorothiazide and Bipolar Disorder

ArticleYear
Lithium and antihypertensive medication: a potentially dangerous interaction.
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Antimanic Agents; Bipolar Disorde

2009
Lithium toxicity induced by triamterene-hydrochlorothiazide.
    Postgraduate medical journal, 1980, Volume: 56, Issue:661

    Topics: Bipolar Disorder; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; H

1980
Inappropriate secretion of antidiuretic hormone and SSRIs.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 169, Issue:4

    Topics: Aged; Bipolar Disorder; Citalopram; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide;

1996
Lithium toxicity.
    The Journal of the Medical Society of New Jersey, 1979, Volume: 76, Issue:10

    Topics: Bipolar Disorder; Drug Interactions; Heart; Humans; Hydrochlorothiazide; Lithium; Male; Middle Aged

1979
Distribution of rubidium in the organism.
    Neuropsychobiology, 1977, Volume: 3, Issue:2-3

    Topics: Administration, Oral; Animals; Bipolar Disorder; Brain; Cesium; Erythrocytes; Half-Life; Humans; Hyd

1977
[A case of lithium intoxication at therapeutic lithium dosage due to additional diuretic therapy (author's transl)].
    Wiener klinische Wochenschrift, 1978, May-26, Volume: 90, Issue:11

    Topics: Amiloride; Bipolar Disorder; Drug Combinations; Drug Interactions; Haloperidol; Humans; Hydrochlorot

1978
Diuretic-induced lithium toxicity presenting as mania.
    The Journal of nervous and mental disease, 1985, Volume: 173, Issue:5

    Topics: Bipolar Disorder; Diagnosis, Differential; Female; Humans; Hydrochlorothiazide; Hypertension; Kineti

1985