Compounds > hydrochlorothiazide
Page last updated: 2024-10-28

hydrochlorothiazide and Ascites

hydrochlorothiazide has been researched along with Ascites in 42 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Ascites: Accumulation or retention of free fluid within the peritoneal cavity.

Research Excerpts

ExcerptRelevanceReference
"In cirrhotic patients low-dose captopril seems to be efficient in the treatment of ascites resistant to diuretics without causing major side effects."7.67[Effect of captopril therapy on sodium and water excretion in patients with liver cirrhosis and ascites]. ( Brunkhorst, R; Koch, K; Kühn, K; Schmidt, FW; Wrenger, E, 1989)
"In cirrhotic patients low-dose captopril seems to be efficient in the treatment of ascites resistant to diuretics without causing major side effects."3.67[Effect of captopril therapy on sodium and water excretion in patients with liver cirrhosis and ascites]. ( Brunkhorst, R; Koch, K; Kühn, K; Schmidt, FW; Wrenger, E, 1989)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199040 (95.24)18.7374
1990's1 (2.38)18.2507
2000's1 (2.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weingärtner, O1
Böhm, M1
Laufs, U1
KERR, DN1
READ, AE1
SHERLOCK, S1
CASSANO, A1
CONTI, F1
COSTA, C1
CORDOVA, C1
EDELSTEIN, SG1
FLESCHER, R1
MORRISON, RS1
SHEPS, MC1
HOWARD, FA1
CHALMERS, TC1
RODECK, H2
TROPITZSCH, L1
EL-EBRASHY, N1
GANTT, CL1
ECKLUND, RE1
STEIGMANN, F2
SISON, A1
DUBIN, A2
CARPENTER, CJ1
MITRA, P1
SELLER, RH1
FUCHS, M1
SWARTZ, C1
BREST, AN1
MOYER, JH1
PEREZ, V1
PICCALUGA, A1
ALVAREZ, A1
LEW, V1
RATTI, J1
SALA, G1
D AMICO, G1
VITERTARI, L1
CASTELLUCCIO, A1
POLLI, E2
ALVAREZ, S1
TRIANTAFILIDES, T1
CASIROLA, G2
TARTARA, A1
CHERIE LIGNIERE, E1
ARMASCRUZ, R1
GOMEZ, R1
MARDONES, J1
PLAZADELOSREYES, M1
CHERIE LIGNIERE, EL1
POZZI, E1
BORRELLI, PL1
CAIRELLA, M1
DEMARTIIS, M1
LONGO, T1
FORTI, D1
MELLONI, GF1
BARATTA, C1
MARANGONI, R1
MERLO, L1
ANTOGNETTI, R1
FLETCHER, CB1
EAKIN, EL1
ROTHMAN, PE1
GINSBERG, DJ1
SAAD, A1
GABUZDA, GJ1
BELLUSCHI, A1
OFSTAD, J1
Gagnon, O1
Gertman, PM1
Iber, FL1
Descos, L1
Gauthier, A1
Levy, VG1
Michel, H1
Quinton, A1
Rueff, B1
Fermanian, J1
Fombonne, E1
Durbec, JP1
Clearfield, H1
Knauf, H1
Mutschler, E1
Castagnolo, B1
De Colibus, V1
Napolitano, L1
Aliperta, A1
Caldarelli, G1
Abignente, F1
Szabó, G1
Serényi, P1
Magyar, Z1
Bianchi Porre, G1
Lazzaroni, M1
Petrillo, M1
Brunkhorst, R1
Wrenger, E1
Kühn, K1
Schmidt, FW1
Koch, K1
Munshi, CP1
Sawkar, LA1
Vaidya, PM1
Gulati, OD1
Schnack, H1
Buligescu, L1
Candiori, R1
Yamada, S1
Reynolds, TB2
Lieberman, FL2
Bateman, JR1
Păunescu-Podanu, A1
Demirian, H1
Ionitã, C1
Georgescu, D1
Tarachiu, A1
Anghel, R1
Rubingher, L1
Robert, M1
Portmann, B1
Fu, FY1
T'ang, MK1
Cheng, CS1
Liu, H1
Lu, ST1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Resistant Hypertension On Treatment - Sequential Nephron Blockade Compared to Dual Blockade of the Renin-angiotensin-aldosterone System Plus Bisoprolol in the Treatment of Resistant Arterial Hypertension: A Randomized Trial (ResHypOT)[NCT02832973]Phase 472 participants (Actual)Interventional2015-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for hydrochlorothiazide and Ascites

ArticleYear
Comparison of six treatments of ascites in patients with liver cirrhosis. A clinical trial.
    Hepato-gastroenterology, 1983, Volume: 30, Issue:1

    Topics: Amiloride; Ascites; Blood Chemical Analysis; Clinical Trials as Topic; Diet, Sodium-Restricted; Diur

1983
[Clinical evaluation of the use of diuretics in the ascitic phase of hepatic cirrhosis].
    La Clinica terapeutica, 1977, Dec-31, Volume: 83, Issue:6

    Topics: Acute Disease; Adult; Aged; Amiloride; Ascites; Clinical Trials as Topic; Diuretics; Drug Evaluation

1977
[Letter: Ascrtogenicliver cirrhosis. Effect of amiloride on water-electrolytemetabolsim].
    La Nouvelle presse medicale, 1975, Apr-05, Volume: 4, Issue:14

    Topics: Amiloride; Ascites; Chlorides; Clinical Trials as Topic; Furosemide; Humans; Hydrochlorothiazide; Hy

1975
Comparative efficacy of spironolactone and hydrochlorothiazide (separately and in combination) in cirrhotic edema.
    The Journal of the Association of Physicians of India, 1967, Volume: 15, Issue:12

    Topics: Ascites; Clinical Trials as Topic; Drug Synergism; Humans; Hydrochlorothiazide; Liver Cirrhosis; Spi

1967
[Modern diuretic therapy in chronic liver diseases].
    Wiener medizinische Wochenschrift (1946), 1965, Sep-25, Volume: 115, Issue:39

    Topics: Adult; Aged; Ascites; Clinical Trials as Topic; Diuretics; Female; Furosemide; Humans; Hydrochloroth

1965
Amiloride (MK-870), a new antikaluretic diuretic. Comparison to other antikaluretic diuretics in patients with liver disease and ascites.
    Gastroenterology, 1970, Volume: 59, Issue:6

    Topics: Acid-Base Equilibrium; Amidines; Ascites; Autopsy; Carcinoma; Diuretics; Ethacrynic Acid; Humans; Hy

1970

Other Studies

36 other studies available for hydrochlorothiazide and Ascites

ArticleYear
[67-year-old patient with abdominal pain and pronounced peritonitis].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:22

    Topics: Abdominal Pain; Aged; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents;

2009
Dihydrochlorothiazide in control of ascites.
    Lancet (London, England), 1959, Jun-13, Volume: 1, Issue:7085

    Topics: Acetazolamide; Ascites; Humans; Hydrochlorothiazide; Liver Diseases

1959
[Studies of diuresis caused by hydrochlorothiazide].
    La Riforma medica, 1959, Jun-13, Volume: 73, Issue:24

    Topics: Acetazolamide; Ascites; Diuresis; Diuretics; Heart Failure; Humans; Hydrochlorothiazide; Liver Cirrh

1959
A controlled double-blind evaluation of hydroflumethiazide and hydrochlorothiazide.
    The New England journal of medicine, 1961, Feb-02, Volume: 264

    Topics: Ascites; Chlorothiazide; Double-Blind Method; Hydrochlorothiazide; Hydroflumethiazide; Liver Cirrhos

1961
[Studies on the problem of the effect of hydrochlorothiazide on carcinomatous ascites].
    Die Medizinische Welt, 1961, Apr-29, Volume: 17

    Topics: Ascites; Chlorothiazide; Humans; Hydrochlorothiazide; Neoplasms; Peritoneal Neoplasms

1961
[On the effects of hydrochlorothiazide on carcinomatous ascites].
    Klinische Wochenschrift, 1961, Apr-01, Volume: 39

    Topics: Animals; Ascites; Chlorothiazide; Hydrochlorothiazide; Neoplasms, Experimental; Peritoneal Neoplasms

1961
Trial of hydrochlorothiazide in ascites of bilharzial hepatolienal fibrosis.
    The Journal of the Egyptian Medical Association, 1962, Volume: 45

    Topics: Animals; Ascites; Chlorothiazide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Schistosoma

1962
Significance of aldosterone antagonism in the treatment of edema and ascites.
    The American journal of medicine, 1962, Volume: 33

    Topics: Aldosterone; Antihypertensive Agents; Ascites; Chlorothiazide; Diuretics; Edema; Humans; Hydrochloro

1962
"Intractable" ascites in cirrhosis: its management by a multiple diuretic approach.
    The American journal of the medical sciences, 1963, Volume: 245

    Topics: Ascites; Bendroflumethiazide; Disease Management; Diuretics; Humans; Hydrochlorothiazide; Hydroxypro

1963
SPIRONOLACTONE IN ASCITES OF HEPATIC CIRRHOSIS: PRELIMINARY OBSERVATIONS.
    Bulletin of the Calcutta School of Tropical Medicine, 1963, Volume: 11

    Topics: Ascites; Ephedrine; Humans; Hydrochlorothiazide; Liver Cirrhosis; Spironolactone

1963
TREATMENT OF EDEMA BY THE COMBINED ADMINISTRATION OF CHEMICALLY DIFFERENT DIURETIC AGENTS.
    The American journal of cardiology, 1963, Volume: 12

    Topics: Ascites; Chlorthalidone; Diuretics; Edema; Heart Failure; Humans; Hydrochlorothiazide; Organomercury

1963
[TREATMENT OF ASCITES IN HEPATIC CIRRHOSIS. 2].
    Prensa medica argentina, 1963, Jun-21, Volume: 50

    Topics: Ascites; Dexamethasone; Diet, Sodium-Restricted; Hydrochlorothiazide; Liver Cirrhosis; Prognosis; Sp

1963
[CLINICAL RESEARCH ON A NEW DIURETIC: TRIAMTERENE].
    Minerva medica, 1963, Oct-20, Volume: 54

    Topics: Ascites; Diabetes Insipidus; Diuretics; Edema; Humans; Hydrochlorothiazide; Hyperaldosteronism; Live

1963
"REFRACTORY" ASCITES OF CIRRHOSIS: NEWER THERAPEUTIC PROCEDURES.
    Connecticut medicine, 1964, Volume: 28

    Topics: Ascites; Bendroflumethiazide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Prednisone; Spironolacto

1964
[ON THE ACTION OF TRIAMTERENE ON SALIDIURESIS CAUSED BY HYDROCHLOROTHIAZIDE].
    Gazzetta medica italiana, 1963, Volume: 122

    Topics: Ascites; Diuresis; Diuretics; Edema; Heart Failure; Hepatitis; Hydrochlorothiazide; Hypertension; Hy

1963
[NATRIURETIC DRUGS].
    Revista medica de Chile, 1963, Volume: 91

    Topics: Acetazolamide; Aldosterone; Ascites; Chlorothiazide; Dexamethasone; Diabetes Insipidus; Diuresis; Di

1963
[INFLUENCE OF TRIAMTERENE ON SALIDIURESIS AND RENAL HEMODYNAMICS OF INDIVIDUALS WITH ASCITOGENIC HEPATIC CIRRHOSIS IN TREATMENT WITH HYDROCHLOROTHIAZIDE].
    Rivista di patologia e clinica, 1963, Volume: 18

    Topics: Ascites; Blood Circulation; Diuresis; Diuretics; Electrolytes; Hemodynamics; Hydrochlorothiazide; Ki

1963
[OBSERVATIONS ON THE CLINICAL USE OF TRIAMTERENE IN TREATMENT OF THE ASCITES OF HEPATIC CIRRHOSIS].
    La Clinica terapeutica, 1964, Jun-15, Volume: 29

    Topics: Ascites; Diuretics; Humans; Hydrochlorothiazide; Liver Cirrhosis; Pterins; Spironolactone; Triamtere

1964
[AUTOPERFUSION OF ASCITIC FLUID AND DIURETIC TREATMENT IN PREPARATION FOR SURGERY IN CIRRHOTIC PATIENTS].
    Minerva medica, 1964, Jun-13, Volume: 55

    Topics: Ascites; Ascitic Fluid; Diet, Sodium-Restricted; Diuretics; Humans; Hydrochlorothiazide; Liver Cirrh

1964
[ON MODIFICATIONS OF PLASMA AND URINARY ELECTROLYTES IN ASCITOGENIC HEPATIC CIRRHOSIS IN TREATMENT WITH TRIAMTERENE ALONE AND ASSOCIATED WITH HYDROCHLOROTHIAZIDE AND WITH SPIRONOLACTONE].
    Minerva medica, 1964, Sep-15, Volume: 55

    Topics: Ascites; Biomedical Research; Chlorides; Electrolytes; Geriatrics; Humans; Hydrochlorothiazide; Live

1964
FETAL ASCITES--LIVER GIANT-CELL TRANSFORMATION. REPORT OF A CASE WITH RECOVERY.
    American journal of diseases of children (1960), 1964, Volume: 108

    Topics: Ascites; Biopsy; Drainage; Exchange Transfusion, Whole Blood; Fetal Diseases; Humans; Hydrochlorothi

1964
METABOLIC STUDIES WITH THE DIURETIC TRIAMTERENE IN PATIENTS WITH CIRRHOSIS AND ASCITES.
    The New England journal of medicine, 1964, Dec-10, Volume: 271

    Topics: Ammonia; Ascites; Blood; Carbon Dioxide; Chlorides; Creatine; Creatinine; Diuresis; Diuretics; Drug

1964
[CLINICAL RESEARCH ON A NEW DRUG COMBINATION WITH DIURETIC ACTION].
    La Clinica terapeutica, 1964, Oct-31, Volume: 31

    Topics: Ascites; Biomedical Research; Diuretics; Drug Combinations; Drug Therapy; Edema; Heart Failure; Hydr

1964
Hydrochlorothiazide in hepatic cirrhosis with ascites.
    Acta medica Scandinavica, 1960, May-20, Volume: 167

    Topics: Ascites; Chlorothiazide; Hydrochlorothiazide; Liver Cirrhosis; Organic Chemicals

1960
Comparison of oral isosorbide and intravenous mannitol as adjuncts to the diuresis of patients with cirrhosis of the liver.
    The American journal of the medical sciences, 1967, Volume: 254, Issue:3

    Topics: Adult; Ascites; Humans; Hydrochlorothiazide; Injections, Intravenous; Isosorbide Dinitrate; Liver Ci

1967
Drug therapy of ascites.
    American family physician, 1981, Volume: 23, Issue:1

    Topics: Ascites; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Sodium Chloride Sympor

1981
Sequential nephron blockade breaks resistance to diuretics in edematous states.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:3

    Topics: Acetazolamide; Adult; Ascites; Diuresis; Diuretics; Edema; Female; Furosemide; Heart Failure; Humans

1997
The effect of diuretic drugs on lymph flow in experimental ascites.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:3

    Topics: Alkylmercury Compounds; Animals; Ascites; Blood Pressure; Diuretics; Dogs; Ethacrynic Acid; Female;

1979
[Effect of captopril therapy on sodium and water excretion in patients with liver cirrhosis and ascites].
    Klinische Wochenschrift, 1989, Aug-01, Volume: 67, Issue:15

    Topics: Adult; Aged; Ascites; Blood Pressure; Captopril; Diuresis; Diuretics; Dose-Response Relationship, Dr

1989
[Modern diuretics in the treatment of ascites caused by hepatic cirrhosis].
    Medicina interna, 1970, Volume: 22, Issue:5

    Topics: Adult; Aged; Aldosterone; Ascites; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Liver

1970
Megaloblastic anemia possibly induced by triamterene in patients with alcoholic cirrhosis. Two case reports.
    Annals of internal medicine, 1968, Volume: 68, Issue:1

    Topics: Adult; Aged; Alcoholism; Anemia, Macrocytic; Ascites; Bone Marrow Cells; Bone Marrow Examination; Er

1968
[Clinical and biochemical study of the therapeutic effect of the diuretic triamterene in ascitogenic cirrhosis].
    Medicina interna, 1968, Volume: 20, Issue:5

    Topics: Adrenal Cortex Hormones; Ascites; Diuresis; Electrolytes; Humans; Hydrochlorothiazide; Liver Cirrhos

1968
[Influence of diuretics on the survival of 180 patients with cirrhosis of the liver and ascites].
    Schweizerische medizinische Wochenschrift, 1969, Feb-08, Volume: 99, Issue:6

    Topics: Adult; Aged; Alcoholism; Ascites; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Humans

1969
[Effects of triamterene in combination with other diuretics in liver cirrhosis].
    Minerva medica, 1963, Oct-10, Volume: 54, Issue:81 Suppl

    Topics: Ascites; Bendroflumethiazide; Chlorothiazide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Spironol

1963
Renal failure with cirrhosis. Observations on the role of diuretics.
    Annals of internal medicine, 1966, Volume: 64, Issue:6

    Topics: Acute Kidney Injury; Aminohippuric Acids; Ascites; Blood; Blood Volume; Creatine; Diuretics; Ethacry

1966
Medical management of ascites in hepatic cirrhosis.
    Chinese medical journal (Peking, China : 1932), 1966, Volume: 85, Issue:5

    Topics: Adolescent; Adult; Aminophylline; Anabolic Agents; Ascites; China; Diet, Sodium-Restricted; Female;

1966