Page last updated: 2024-10-28

hydrochlorothiazide and Arterial Diseases, Carotid

hydrochlorothiazide has been researched along with Arterial Diseases, Carotid in 5 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
" After a 4-week wash-out period, 209 patients were randomized to either CC 8 mg or AML 5 mg once daily for a minimum of 1 month, after which, if BP was not normalized, the dosage was doubled, followed by the addition of hydrochlorothiazide 12."2.74Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study. ( Asmar, R; Baguet, JP; Mallion, JM; Nisse-Durgeat, S; Valensi, P, 2009)
"Isradipine is a new dihydropyridine calcium antagonist that is highly effective in lowering blood pressure."2.67A comparison of antihypertensive drug effects on the progression of extracranial carotid atherosclerosis. The Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS). ( Bond, G; Brugger, S; Byington, R; Flack, JM; Grimm, RH, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kolos, I1
Troitskiy, A1
Balakhonova, T1
Shariya, M1
Skrypnik, D1
Tvorogova, T1
Deev, A1
Boytsov, S1
Baguet, JP1
Asmar, R1
Valensi, P1
Nisse-Durgeat, S1
Mallion, JM1
Byington, RP2
Craven, TE1
Furberg, CD1
Pahor, M1
Borhani, NO1
Brugger, SB1
Grimm, RH1
Flack, JM1
Byington, R1
Bond, G1
Brugger, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Preoperative Identification of the Histologically Vulnerable Plaque Using Non-invasive Imaging, Biomechanical Assessment and Baroreflex Evaluation in Patients With Severe Carotid Stenosis"[NCT05566080]100 participants (Actual)Observational2021-03-15Completed
Carotid Endarterectomy Versus Optimal Medical Treatment of Asymptomatic High Grade Carotid Artery Stenosis[NCT00805311]Phase 4400 participants (Actual)Interventional2009-04-30Terminated (stopped due to Due to the clear advantage of carotid endarterectomy)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for hydrochlorothiazide and Arterial Diseases, Carotid

ArticleYear
Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis.
    Journal of vascular surgery, 2015, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Arteriosclerosis; Atorvastatin; Carotid Artery Diseases; Endarterectomy, Carotid;

2015
Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis.
    Journal of vascular surgery, 2015, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Arteriosclerosis; Atorvastatin; Carotid Artery Diseases; Endarterectomy, Carotid;

2015
Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis.
    Journal of vascular surgery, 2015, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Arteriosclerosis; Atorvastatin; Carotid Artery Diseases; Endarterectomy, Carotid;

2015
Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis.
    Journal of vascular surgery, 2015, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Arteriosclerosis; Atorvastatin; Carotid Artery Diseases; Endarterectomy, Carotid;

2015
Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study.
    Vascular health and risk management, 2009, Volume: 5, Issue:1

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles;

2009
Isradipine, raised glycosylated haemoglobin, and risk of cardiovascular events.
    Lancet (London, England), 1997, Oct-11, Volume: 350, Issue:9084

    Topics: Arteriosclerosis; Blood Glucose; Calcium Channel Blockers; Cardiovascular Diseases; Carotid Artery D

1997
Multicenter study with isradipine and diuretics against atherosclerosis. US MIDAS Research Group.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 1

    Topics: Arteriosclerosis; Calcium Channel Blockers; Carotid Artery Diseases; Coronary Artery Disease; Diuret

1990
A comparison of antihypertensive drug effects on the progression of extracranial carotid atherosclerosis. The Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS).
    Drugs, 1990, Volume: 40 Suppl 2

    Topics: Adult; Antihypertensive Agents; Arteriosclerosis; Carotid Artery Diseases; Double-Blind Method; Fema

1990