hydrochlorothiazide has been researched along with Angina Pectoris in 19 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " During long-term administration the diuretic did not prevent a significant diminution of the nitrate effects." | 6.67 | [The effect of diuretics on the magnitude of the effect of isosorbide dinitrate given as a single dose and after long-term administration. Ergometric study in patients with stable angina pectoris]. ( Bocek, O; Janousek, S; Manousek, J; Rotrekl, P; Semrád, B; Vlasicová, Y; Vlasínová, J, 1994) |
| "Felodipine, a dihydropyridine calcium-channel antagonist, significantly reduces systolic and diastolic blood pressure (BP) in patients with hypertension and has been associated with beneficial hemodynamic effects in patients with chronic stable angina pectoris or congestive heart failure (CHF)." | 6.16 | Felodipine: a new dihydropyridine calcium-channel antagonist. ( Lopez, LM; Yedinak, KC, 1991) |
| "Sustained-release diltiazem (D-SR) and sustained-release verapamil (V-SR) when given twice a day have been successfully used to treat both essential hypertension and angina pectoris." | 4.77 | Treatment of angina pectoris and hypertension with sustained-release calcium channel-blocking drugs. ( Klein, MD; Weiner, DA, 1987) |
| "There is significant controversy around whether chlorthalidone (CTD) is superior to hydrochlorothiazide (HCTZ) in hypertension management." | 3.77 | Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis. ( Bleske, BE; Dorsch, MP; Erickson, SR; Gillespie, BW; Weder, AB, 2011) |
| "We studied 14 patients to determine whether sustained-release diltiazem is a satisfactory long-term substitute for the combination of propranolol plus hydrochlorothiazide (HCTZ), control phase, in the treatment of systemic hypertension with coexisting chronic stable angina pectoris." | 3.67 | Response of blood pressure, cardiac output, peripheral resistance, and exercise performance to substitution of calcium blocker for beta-blocker plus thiazide diuretic therapy in patients with both systemic hypertension and mild stable angina. ( Gonzales, A; Kawanishi, DT; O'Rourke, RA; Rahimtoola, SH; Reid, CL, 1989) |
| " During long-term administration the diuretic did not prevent a significant diminution of the nitrate effects." | 2.67 | [The effect of diuretics on the magnitude of the effect of isosorbide dinitrate given as a single dose and after long-term administration. Ergometric study in patients with stable angina pectoris]. ( Bocek, O; Janousek, S; Manousek, J; Rotrekl, P; Semrád, B; Vlasicová, Y; Vlasínová, J, 1994) |
| " The measure was used to survey compliance with 20 common drugs prescribed to 419 outpatients for long-term administration on regular schedules." | 1.26 | Variations in patient compliance with common long-term drugs. ( Carter, WB; Dohan, JJ; Inui, TS; Pearlman, RA; Pecoraro, RE, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dorsch, MP | 1 |
| Gillespie, BW | 1 |
| Erickson, SR | 1 |
| Bleske, BE | 1 |
| Weder, AB | 1 |
| PREZIOSI, P | 1 |
| MIELE, E | 1 |
| MARMO, E | 1 |
| COHEN, MH | 1 |
| Medkova, IL | 1 |
| Ieromuzo, AA | 1 |
| Ivanov, AN | 1 |
| Mosiakina, LI | 1 |
| Biriukova, LS | 1 |
| Finimundi, HC | 1 |
| Caramori, PA | 1 |
| Parker, JD | 3 |
| Macleod, MD | 1 |
| Bell, GM | 1 |
| Irvine, WJ | 1 |
| Inui, TS | 1 |
| Carter, WB | 1 |
| Pecoraro, RE | 1 |
| Pearlman, RA | 1 |
| Dohan, JJ | 1 |
| Rotrekl, P | 1 |
| Vlasínová, J | 1 |
| Manousek, J | 1 |
| Bocek, O | 1 |
| Vlasicová, Y | 1 |
| Janousek, S | 1 |
| Semrád, B | 1 |
| Sussex, BA | 1 |
| Campbell, NR | 1 |
| Raju, MK | 1 |
| McKay, DW | 1 |
| Parker, AB | 1 |
| Farrell, B | 1 |
| Parker, JO | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Yedinak, KC | 1 |
| Lopez, LM | 1 |
| Kawanishi, DT | 1 |
| Reid, CL | 1 |
| Gonzales, A | 1 |
| O'Rourke, RA | 1 |
| Rahimtoola, SH | 1 |
| Klein, MD | 1 |
| Weiner, DA | 1 |
| Strozzi, C | 1 |
| Padula, A | 1 |
| Russo, L | 1 |
| Alfiero, R | 1 |
| Rizzo, A | 1 |
| Sweet, RL | 1 |
| Sheffield, LT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Randomized Single-blind Trial of Amiloride in Coronary Heart Disease[NCT01231165] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydrochlorothiazide and Angina Pectoris
| Article | Year |
|---|---|
Diuretic therapy and angina pectoris.
Topics: Administration, Cutaneous; Administration, Sublingual; Amiloride; Analysis of Variance; Angina Pecto | 1998 |
Felodipine: a new dihydropyridine calcium-channel antagonist.
Topics: Angina Pectoris; Animals; Blood Pressure; Double-Blind Method; Felodipine; Heart Failure; Humans; Hy | 1991 |
Treatment of angina pectoris and hypertension with sustained-release calcium channel-blocking drugs.
Topics: Angina Pectoris; Biological Availability; Calcium Channel Blockers; Delayed-Action Preparations; Dil | 1987 |
8 trials available for hydrochlorothiazide and Angina Pectoris
| Article | Year |
|---|---|
[The treatment of coronary heart disease by beta-adrenoblockers or tiazide diuretics preparation in combination with vegetarian diet].
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Atenolol; Combined Modality Therapy; Diet, Vege | 2005 |
Effect of diuretic therapy on exercise capacity in patients with chronic angina and preserved left ventricular function.
Topics: Aged; Amiloride; Angina Pectoris; Blood Pressure; Chronic Disease; Diuretics; Double-Blind Method; D | 2007 |
[The effect of diuretics on the magnitude of the effect of isosorbide dinitrate given as a single dose and after long-term administration. Ergometric study in patients with stable angina pectoris].
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Drug Synergism; Electrocardiography; Exercise Test; He | 1994 |
The antianginal efficacy of isosorbide dinitrate therapy is maintained during diuretic treatment.
Topics: Aged; Amiloride; Angina Pectoris; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Ex | 1994 |
Effects of diuretic therapy on the development of tolerance to nitroglycerin and exercise capacity in patients with chronic stable angina.
Topics: Administration, Cutaneous; Amiloride; Angina Pectoris; Blood Pressure; Chronic Disease; Cross-Over S | 1996 |
Diuretic therapy and angina pectoris.
Topics: Administration, Cutaneous; Administration, Sublingual; Amiloride; Analysis of Variance; Angina Pecto | 1998 |
Timolol: a preliminary report of its pharmacological properties and therapeutic efficacy in angina and hypertension.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Antihypertensive Agents; Cats; Clinical Trial | 1975 |
Felodipine: a new dihydropyridine calcium-channel antagonist.
Topics: Angina Pectoris; Animals; Blood Pressure; Double-Blind Method; Felodipine; Heart Failure; Humans; Hy | 1991 |
10 other studies available for hydrochlorothiazide and Angina Pectoris
| Article | Year |
|---|---|
Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis.
Topics: Adult; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Cholesterol; Heart | 2011 |
[Experimental research on the anti-stenocardiac effect of hydrochlorothiazide and some benzothiadiazine diuretics].
Topics: Angina Pectoris; Benzothiadiazines; Hydrochlorothiazide; Sodium Chloride Symporter Inhibitors | 1961 |
PROLONGED CARDIOGENIC SHOCK WITH RECOVERY.
Topics: Angina Pectoris; Coronary Disease; Digoxin; Electrocardiography; Hydrochlorothiazide; Hypercholester | 1964 |
Nephrogenic diabetes insipidus associated with Dyazide (triamterene-hydrochlorothiazide).
Topics: Aged; Angina Pectoris; Diabetes Insipidus; Diabetic Nephropathies; Diuretics; Drug Combinations; Hum | 1981 |
Variations in patient compliance with common long-term drugs.
Topics: Angina Pectoris; Blood Pressure; Drug Therapy; Humans; Hydrochlorothiazide; Hypertension; Patient Co | 1980 |
Response of blood pressure, cardiac output, peripheral resistance, and exercise performance to substitution of calcium blocker for beta-blocker plus thiazide diuretic therapy in patients with both systemic hypertension and mild stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Delayed-Action Preparations; | 1989 |
[Ergometric evaluation of effects of captopril in hypertensive patients with exertion-induced angina].
Topics: Aged; Angina Pectoris; Captopril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldop | 1985 |
When a drug is the culprit.
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Clofibrate; Depression; Drug-Related Side Effect | 1973 |
Myocardial infarction after exercise-induced electrocardiographic changes in a patient with variant angina pectoris.
Topics: Amitriptyline; Angina Pectoris; Arteriosclerosis; Catheterization; Diabetes Complications; Electroca | 1974 |
Report of the panels on cardiovascular drugs from the drug efficacy study.
Topics: Angina Pectoris; Cardiovascular Diseases; Chlorothiazide; Digitalis Glycosides; Drug Industry; Drug | 1970 |