hydrochlorothiazide has been researched along with Aldosteronism in 38 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study reported here prospectively evaluated the prevention of diuretic-induced secondary hyperaldosteronism and hypokalemia by a converting enzyme inhibitor, enalapril (MK 421)." | 9.05 | Reversal of diuretic-induced secondary hyperaldosteronism and hypokalemia by enalapril (MK-421): a new angiotensin-converting enzyme inhibitor. ( Aurecchia, SA; Griffing, GT; Melby, JC; Sindler, BH, 1983) |
| "This presentation is a summary of our recent clinical studies on the therapeutic use of a new potassium-sparing diuretic, amiloride, and a converting enzyme inhibitor, MK-421, in preventing hypokalemia associated with primary and secondary hyperaldosteronism." | 9.05 | The therapeutic use of a new potassium-sparing diuretic, amiloride, and a converting enzyme inhibitor, MK-421, in preventing hypokalemia associated with primary and secondary hyperaldosteronism. ( Griffing, GT; Melby, JC, 1983) |
| " We investigated the feasibility of treating a group of eight patients with hyperaldosteronism with a triamterene-thiazide combination to induce volume depletion and increase serum potassium concentration." | 7.66 | Triamterene-thiazide combination: alternative therapy for primary aldosteronism. ( Ganguly, A; Weinberger, MH, 1981) |
| "The study reported here prospectively evaluated the prevention of diuretic-induced secondary hyperaldosteronism and hypokalemia by a converting enzyme inhibitor, enalapril (MK 421)." | 5.05 | Reversal of diuretic-induced secondary hyperaldosteronism and hypokalemia by enalapril (MK-421): a new angiotensin-converting enzyme inhibitor. ( Aurecchia, SA; Griffing, GT; Melby, JC; Sindler, BH, 1983) |
| "This presentation is a summary of our recent clinical studies on the therapeutic use of a new potassium-sparing diuretic, amiloride, and a converting enzyme inhibitor, MK-421, in preventing hypokalemia associated with primary and secondary hyperaldosteronism." | 5.05 | The therapeutic use of a new potassium-sparing diuretic, amiloride, and a converting enzyme inhibitor, MK-421, in preventing hypokalemia associated with primary and secondary hyperaldosteronism. ( Griffing, GT; Melby, JC, 1983) |
| "We hypothesized that aldosteronism is accompanied by hypercalciuria and hypermagnesuria that lead to bone loss, which could be rescued by hydrochlorothiazide and spironolactone." | 3.73 | Bone loss in rats with aldosteronism. ( Bhattacharya, SK; Chhokar, VS; Runyan, AL; Runyan, JW; Sun, Y; Weber, KT, 2005) |
| " We investigated the feasibility of treating a group of eight patients with hyperaldosteronism with a triamterene-thiazide combination to induce volume depletion and increase serum potassium concentration." | 3.66 | Triamterene-thiazide combination: alternative therapy for primary aldosteronism. ( Ganguly, A; Weinberger, MH, 1981) |
| "Despite the sustained secondary hyperaldosteronism, however, urinary 19-nor-DOC extraction, measured by RIA, increased only slightly on day 3 and subsequently decreased to normal values throughout the remainder of the study (19-nor-DOC, 103 +/- 27 ng/day 0, 175 +/- 26 on day 3, 127 +/- 27 on day 28)." | 1.27 | Transitory increment in urinary free 19-nor-deoxycorticosterone after diuretic-induced renin stimulation. ( Griffing, GT; Melby, JC; Wilson, TE, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (89.47) | 18.7374 |
| 1990's | 1 (2.63) | 18.2507 |
| 2000's | 3 (7.89) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SALA, G | 1 |
| D AMICO, G | 1 |
| VITERTARI, L | 1 |
| CASTELLUCCIO, A | 1 |
| POLLI, E | 1 |
| PEDERSEN, J | 1 |
| LINDENEG, O | 1 |
| FISCHER, S | 1 |
| BAGROS, P | 1 |
| PARDO, EG | 1 |
| VIDRIO, H | 1 |
| VARGAS, R | 1 |
| COLLYNS, JA | 1 |
| MACQUAIDE, DH | 1 |
| Eide, IK | 1 |
| Torjesen, PA | 1 |
| Drolsum, A | 1 |
| Babovic, A | 1 |
| Lilledahl, NP | 1 |
| Runyan, AL | 1 |
| Chhokar, VS | 1 |
| Sun, Y | 1 |
| Bhattacharya, SK | 1 |
| Runyan, JW | 1 |
| Weber, KT | 1 |
| Gwinup, G | 1 |
| Steinberg, T | 1 |
| Griffing, GT | 3 |
| Sindler, BH | 1 |
| Aurecchia, SA | 1 |
| Melby, JC | 3 |
| Wilson, TE | 1 |
| Ganguly, A | 1 |
| Weinberger, MH | 1 |
| Stepan, VM | 1 |
| Hammer, HF | 1 |
| Krejs, GJ | 1 |
| Ozgür, B | 1 |
| Kürsat, S | 1 |
| Gunnells, JC | 1 |
| McGuffin, WL | 1 |
| Rorive, G | 1 |
| Krzesinski, JM | 1 |
| Stimpel, M | 1 |
| Dralle, H | 1 |
| von zur Mühlen, A | 1 |
| López Jiménez, M | 1 |
| Barbado, FJ | 1 |
| Mateos, F | 1 |
| Peña, JM | 1 |
| Gil, A | 1 |
| Arnalich, F | 1 |
| Tovar, I | 1 |
| Alonso, FG | 1 |
| Vázquez Rodríguez, JJ | 1 |
| Erbler, HC | 2 |
| Radó, JP | 2 |
| Szabó, T | 1 |
| Takó, J | 2 |
| Szántó, Z | 1 |
| Kubota, K | 2 |
| Spark, RF | 1 |
| Fukuchi, S | 1 |
| Takenouchi, T | 1 |
| Nakajima, K | 1 |
| Carey, RM | 1 |
| Wooster, LD | 1 |
| Hook, EW | 1 |
| Dustan, HP | 2 |
| Bravo, EL | 2 |
| Tarazi, RC | 2 |
| Marosi, J | 1 |
| Wilson, E | 1 |
| Schnack, H | 1 |
| Maebashi, M | 1 |
| Yoshinaga, K | 1 |
| Miura, K | 1 |
| Goto, K | 1 |
| Katsushima, I | 1 |
| Eto, M | 1 |
| Shioji, R | 1 |
| Torigai, T | 1 |
| Griffith, DP | 1 |
| Oda, T | 1 |
| Ishibahsi, Y | 1 |
| Iida, K | 1 |
| Okano, J | 1 |
| Hashimoto, T | 1 |
| Sugita, K | 1 |
| Narusawa, T | 1 |
| Iino, S | 1 |
| Niitani, H | 1 |
| Dorndorf, W | 1 |
| Lotz, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Cross-sectional Study on Prevalence of Primary Aldosteronism in Resistant Hypertension and Association With Cardiometabolic Complications[NCT04213963] | 100 participants (Anticipated) | Observational | 2011-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for hydrochlorothiazide and Aldosteronism
| Article | Year |
|---|---|
Low renin hypertension.
Topics: Adult; Age Factors; Diagnosis, Differential; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism | 1975 |
[Properties and indications of potassium-sparing diuretics].
Topics: Amiloride; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hy | 1986 |
5 trials available for hydrochlorothiazide and Aldosteronism
| Article | Year |
|---|---|
Low-renin status in therapy-resistant hypertension: a clue to efficient treatment.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents | 2004 |
Reversal of diuretic-induced secondary hyperaldosteronism and hypokalemia by enalapril (MK-421): a new angiotensin-converting enzyme inhibitor.
Topics: Angiotensin-Converting Enzyme Inhibitors; Dipeptides; Diuretics; Electrolytes; Enalapril; Humans; Hy | 1983 |
The therapeutic use of a new potassium-sparing diuretic, amiloride, and a converting enzyme inhibitor, MK-421, in preventing hypokalemia associated with primary and secondary hyperaldosteronism.
Topics: Adult; Aged; Aldosterone; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Dipeptides; Diuretics | 1983 |
High doses of spironolactone (Aldactone, SC-14266, Verospirone) alone and in combination with triamterene and-or diuretics in the treatment of refractory edema associated with secondary hyperaldosteronism.
Topics: Adult; Aged; Body Weight; Chlorides; Clinical Trials as Topic; Clopamide; Creatinine; Diet, Sodium-R | 1970 |
[Modern diuretic therapy in chronic liver diseases].
Topics: Adult; Aged; Ascites; Clinical Trials as Topic; Diuretics; Female; Furosemide; Humans; Hydrochloroth | 1965 |
31 other studies available for hydrochlorothiazide and Aldosteronism
| Article | Year |
|---|---|
[CLINICAL RESEARCH ON A NEW DIURETIC: TRIAMTERENE].
Topics: Ascites; Diabetes Insipidus; Diuretics; Edema; Humans; Hydrochlorothiazide; Hyperaldosteronism; Live | 1963 |
[ACUTE MALIGNANT HYPERTENSION WITH SECONDARY ALDOSTERONISM. A CASE IN A 31-YEAR-OLD MAN WITH CONGENITAL UNILATERAL RENAL HYPOPLASIA].
Topics: Alkalosis; Antihypertensive Agents; Blood Chemical Analysis; Congenital Abnormalities; Guanethidine; | 1964 |
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics; | 1964 |
[CONTRIBUTION TO THE STUDY OF EXPERIMENTAL MODELS OF ARTERIAL HYPERTENSION].
Topics: Animals; Chlorisondamine; Classification; Cortisone; Dogs; Ganglionic Blockers; Hydrochlorothiazide; | 1964 |
HYPOKALEMIC ALKALOSIS WITH ADRENAL TUMOR: A CASE REPORT. CONN'S SYNDROME OR DRUG-INDUCED HYPOKALEMIC ALKALOSIS.
Topics: Adenoma; Adrenal Gland Neoplasms; Alkalosis; Drug Therapy; Humans; Hydrochlorothiazide; Hyperaldoste | 1965 |
Bone loss in rats with aldosteronism.
Topics: Animals; Bone Resorption; Calcium; Hydrochlorothiazide; Hyperaldosteronism; Magnesium; Male; Parathy | 2005 |
Differential response to thiazides and spironolactone in primary aldosteronism.
Topics: Adult; Alkalosis; Blood Pressure; Diagnosis, Differential; Humans; Hydrochlorothiazide; Hyperaldoste | 1967 |
Transitory increment in urinary free 19-nor-deoxycorticosterone after diuretic-induced renin stimulation.
Topics: Adult; Chromatography, Thin Layer; Desoxycorticosterone; Female; Humans; Hydrochlorothiazide; Hypera | 1984 |
Triamterene-thiazide combination: alternative therapy for primary aldosteronism.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Blood Pressure; Child; Diuretics; Drug Therapy, | 1981 |
Hyperkalaemia and diarrhoea in a patient with surreptitious ingestion of potassium sparing diuretics.
Topics: Chronic Disease; Diarrhea; Diuretics; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hyper | 1997 |
Hypokalemic rhabdomyolysis aggravated by diuretics complicating Conn's syndrome without acute renal failure.
Topics: Acute Kidney Injury; Adult; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Hyperaldoste | 2002 |
Spironolactone, a reassessment.
Topics: Diuresis; Drug Combinations; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokale | 1975 |
[Therapy of primary aldosteronism].
Topics: Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenalectomy; Carcinoma; Diagnosis, Dif | 1986 |
[Factitious Bartter's syndrome induced by the surreptitious ingestion of diuretics].
Topics: Adult; Bartter Syndrome; Diagnosis, Differential; Diuretics; Factitious Disorders; Female; Furosemid | 1985 |
Inhibition of aldosterone production in diuretic-induced hyperaldosteronism by aldosterone antagonist canrenone in man.
Topics: Aldosterone; Butanes; Depression, Chemical; Diuresis; Hematocrit; Humans; Hydrochlorothiazide; Hyper | 1974 |
The effect of saluretics and spironolactone on aldosterone production and electrolyte excretion in man.
Topics: Adult; Aldosterone; Butanes; Diuresis; Female; Furosemide; Humans; Hydrochlorothiazide; Hyperaldoste | 1974 |
Transitory primary aldosteronism-like condition.
Topics: Aged; Angiotensin II; Chlorides; Diuretics; Female; Heart Diseases; Humans; Hydrochlorothiazide; Hyp | 1968 |
[Study on the renin-angiotensin-aldosterone system. Effects of sodium restriction and postural changes on plasma renin activity and fluctuation in urinary aldosterone].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Chromatography, Thin Layer; Diet, Sodium-Restricted; Hu | 1969 |
Low renin hypertension and the adrenal cortex.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Cor | 1972 |
[Plasma aldosterone levels in primary aldosteronism. 1. Renin-angiotensin system and aldosterone].
Topics: Aldosterone; Angiotensin II; Enzyme Activation; Furosemide; Humans; Hydrochlorothiazide; Hyperaldost | 1973 |
Idiopathic edema.
Topics: Adult; Age Factors; Aldosterone; Edema; Female; Heart Failure; Humans; Hydrochlorothiazide; Hydrosta | 1974 |
Volume-dependent essential and steroid hypertension.
Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Follow-Up Studies; Humans; Hydrochlorothi | 1973 |
Spironolactone as a nonspecific treatment for primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Body Weight; Carbon Dioxide; Creatini | 1973 |
Adrenalectomy for lesions of the adrenal gland.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Medulla; Adrenalectomy; Adult; Aldosterone; Ca | 1967 |
Suppressed plasma renin activity in in hypertensive patients--its evaluation for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Cushing Syndrome; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydrochlorothiaz | 1969 |
[Plasma renin activity in hypertensive and non-hypertensive patients and its clinical significance].
Topics: Addison Disease; Adolescent; Adult; Aged; Aortic Diseases; Biological Assay; Blood Pressure; Blood U | 1970 |
[Potassium clearance in primary aldosteronism].
Topics: Adolescent; Adult; Chlorothiazide; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Male; Mi | 1971 |
Control of hypercalciuria in the immobilized patient.
Topics: Adult; Calcium; Calcium Metabolism Disorders; Calcium, Dietary; Diet Therapy; Extracellular Space; F | 1971 |
[Interesting case of normokalemic primary aldosteronism with thiazide hypokalemia developing into true hypokalemia after relatively short period (4 months)].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Female; Humans; Hydrochlorothiazide; Hypera | 1967 |
[Case of primary aldosteronism--considerations on the thiazide screening test].
Topics: Adrenal Gland Neoplasms; Electrocardiography; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hyper | 1968 |
[Primary hyperaldosteronism (Conn's syndrome)].
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Diet; Female; Humans; Hydrochlorothiazide; Hyperaldosteronis | 1966 |