hydrochlorothiazide has been researched along with Aldosteronism with Hyperplasia of the Adrenal Cortex in 5 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients with Gitelman's syndrome and 23 controls underwent acute administration of the thiazide diuretic hydrochlorothiazide and/or the loop diuretic furosemide (FUR) in order to indirectly evaluate the activity of the two electroneutral Na+/Cl(-)-reabsorptive systems of the distal nephron, namely the thiazide-sensitive Na+-Cl- symporter of the distal convoluted tubule and the FUR-sensitive Na+-K+-2Cl- symporter of the loop of Henle." | 3.69 | Abnormal reabsorption of Na+/CI- by the thiazide-inhibitable transporter of the distal convoluted tubule in Gitelman's syndrome. ( Brunati, C; Colussi, G; De Ferrari, ME; Rombolà, G, 1997) |
| " Although the pharmacology of ROMK channels is still being developed, channel inhibitors have been identified and shown to cause natriuresis and diuresis, in the absence of any significant kaliuresis, on acute oral dosing to rats or dogs." | 1.43 | The Renal Outer Medullary Potassium Channel Inhibitor, MK-7145, Lowers Blood Pressure, and Manifests Features of Bartter's Syndrome Type II Phenotype. ( Alonso-Galicia, M; Corona, A; Felix, JP; Garcia, ML; Gill, C; Hampton, C; Kaczorowski, GJ; Kohler, M; Liu, J; Metzger, JM; Ormes, J; Owens, K; Pai, LY; Pasternak, A; Price, O; Priest, BT; Rasa, C; Roy, S; Shah, K; Sullivan, KA; Tang, H; Thomas-Fowlkes, B; Tong, V; Xiao, J; Zhou, X, 2016) |
| "Although the diagnosis of Gitelman syndrome (GS) and Bartter syndrome (BS) is now feasible by genetic analysis, implementation of genetic testing for these disorders is still hampered by several difficulties, including large gene dimensions, lack of hot-spot mutations, heavy workup time, and costs." | 1.34 | A thiazide test for the diagnosis of renal tubular hypokalemic disorders. ( Bettinelli, A; Bianchetti, MG; Borsa, N; Casari, G; Colussi, G; De Ferrari, ME; Mattiello, C; Syrén, ML; Tedeschi, S, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hampton, C | 1 |
| Zhou, X | 1 |
| Priest, BT | 1 |
| Pai, LY | 1 |
| Felix, JP | 1 |
| Thomas-Fowlkes, B | 1 |
| Liu, J | 1 |
| Kohler, M | 1 |
| Xiao, J | 1 |
| Corona, A | 1 |
| Price, O | 1 |
| Gill, C | 1 |
| Shah, K | 1 |
| Rasa, C | 1 |
| Tong, V | 1 |
| Owens, K | 1 |
| Ormes, J | 1 |
| Tang, H | 1 |
| Roy, S | 1 |
| Sullivan, KA | 1 |
| Metzger, JM | 1 |
| Alonso-Galicia, M | 1 |
| Kaczorowski, GJ | 1 |
| Pasternak, A | 1 |
| Garcia, ML | 1 |
| Colussi, G | 2 |
| Bettinelli, A | 1 |
| Tedeschi, S | 1 |
| De Ferrari, ME | 2 |
| Syrén, ML | 1 |
| Borsa, N | 1 |
| Mattiello, C | 1 |
| Casari, G | 1 |
| Bianchetti, MG | 1 |
| Cantone, A | 1 |
| Yang, X | 1 |
| Yan, Q | 1 |
| Giebisch, G | 1 |
| Hebert, SC | 1 |
| Wang, T | 1 |
| Rombolà, G | 1 |
| Brunati, C | 1 |
| López Jiménez, M | 1 |
| Barbado, FJ | 1 |
| Mateos, F | 1 |
| Peña, JM | 1 |
| Gil, A | 1 |
| Arnalich, F | 1 |
| Tovar, I | 1 |
| Alonso, FG | 1 |
| Vázquez Rodríguez, JJ | 1 |
5 other studies available for hydrochlorothiazide and Aldosteronism with Hyperplasia of the Adrenal Cortex
| Article | Year |
|---|---|
The Renal Outer Medullary Potassium Channel Inhibitor, MK-7145, Lowers Blood Pressure, and Manifests Features of Bartter's Syndrome Type II Phenotype.
Topics: Animals; Bartter Syndrome; Benzimidazoles; Benzofurans; Biphenyl Compounds; Blood Pressure; Dogs; Do | 2016 |
A thiazide test for the diagnosis of renal tubular hypokalemic disorders.
Topics: Adolescent; Adult; Bartter Syndrome; Child; Chronic Disease; Cohort Studies; Diagnosis, Differential | 2007 |
Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity.
Topics: Adaptation, Physiological; Amiloride; Animals; Bartter Syndrome; Cation Transport Proteins; Chloride | 2008 |
Abnormal reabsorption of Na+/CI- by the thiazide-inhibitable transporter of the distal convoluted tubule in Gitelman's syndrome.
Topics: Adolescent; Adult; Bartter Syndrome; Carrier Proteins; Case-Control Studies; Diuretics; Female; Furo | 1997 |
[Factitious Bartter's syndrome induced by the surreptitious ingestion of diuretics].
Topics: Adult; Bartter Syndrome; Diagnosis, Differential; Diuretics; Factitious Disorders; Female; Furosemid | 1985 |