hydrochloric acid has been researched along with Stomach Ulcer in 241 studies
Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was conducted to investigate the inhibitory effect of irsogladine maleate (IM) on gastric ulcers induced by ethanol and hydrochloric acid (HCl)." | 8.02 | Gastroprotective effects of irsogladine maleate on ethanol/hydrochloric acid induced gastric ulcers in mice. ( Kim, JH; Kwon, SC, 2021) |
| " The present study used an animal model to determine the protective effect of silkworm pupa oil on hydrochloric acid / ethanol-induced gastric ulcer." | 7.91 | Protective effect of silkworm pupa oil on hydrochloric acid/ethanol-induced gastric ulcers. ( Liu, X; Long, X; Suo, H; Wang, H; Wang, W; Zhang, Y; Zhao, X, 2019) |
| " This study aimed to determine the role of viable Lactobacillus in the healing of acetic acid-induced chronic gastric ulcer." | 7.76 | Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats. ( Kurakazu, K; Shimizu, K; Uchida, M, 2010) |
| "The gastroprotective activity of phytosphingosine hydrochloride (PS-HCl, CAS 554-62-1) was assessed in four different rat models of experimentally induced gastric ulcer." | 7.73 | Anti-ulcer actions of phytosphingosine hydrochloride in different experimental rat ulcer models. ( Baek, SW; Cho, MH; Jin, HJ; Kim, CK; Kim, JS; Kim, NK; Koh, CW; Kwon, OH; Park, CK, 2005) |
| "We investigated the effect of diacerein, an antiosteoarthritic agent, and its metabolite, rhein, on the production of reactive oxygen species (ROS) from neutrophils as well as the protective effect of diacerein on indomethacin-induced gastric ulceration and its protection mechanism." | 7.71 | Effects of diacerein on indomethacin-induced gastric ulceration. ( Ohmori, K; Tamura, T; Yokoyama, T, 2001) |
| "Levamisole, in doses similar to those required to observe immunostimulation in animals, antagonized dose-dependently, in rats, gastric ulcers produced by necrotizing agents (HCl and ethanol) and NSAIDs (indomethacin and piroxicam) without affecting the anti-inflammatory properties of these latter drugs." | 7.67 | The effect of levamisole on gastric ulcers induced in the rat by anti-inflammatory and necrotizing agents. ( Evangelista, S; Maggi, CA; Meli, A, 1984) |
| "Gastric ulcers were produced in conscious cats in 3 hr by simultaneous intravenous or intragastric administration of acetylsalicylic acid (ASA), plus intravenous infusion of histamine (80 micrograms/kg/hr), pentagastrin (8 micrograms/kg/hr), or intragastric instillation of HCl." | 7.66 | Aspirin-induced gastric ulcers in cats. Prevention by prostacyclin. ( Brzozowski, T; Dembińska-Kieć, A; Konturek, SJ; Piastucki, I; Radecki, T; Zmuda, A, 1981) |
| "In unanesthetized cats, continuous intravenous infusion of aspirin for 36 hr did not produce gastric ulcers when given alone but did when combined with 160 microgram kg-1 hr-1 of histamine-2HCl intravenously." | 7.66 | Histamine augments gastric ulceration produced by intravenous aspirin in cats. ( Aures, D; Grossman, MI; Hansen, DG, 1978) |
| "Gastritis is preponderantly characterized by inflammation of the lining epithelial layer and the chronic gastritis is considered as a pre-cancer lesion." | 5.46 | Olive (Olea europaea) leaf methanolic extract prevents HCl/ethanol-induced gastritis in rats by attenuating inflammation and augmenting antioxidant enzyme activities. ( Abdel Moneim, AE; Al-Quraishy, S; Dkhil, MA; Othman, MS, 2017) |
| "This study was conducted to investigate the inhibitory effect of irsogladine maleate (IM) on gastric ulcers induced by ethanol and hydrochloric acid (HCl)." | 4.02 | Gastroprotective effects of irsogladine maleate on ethanol/hydrochloric acid induced gastric ulcers in mice. ( Kim, JH; Kwon, SC, 2021) |
| " The present study used an animal model to determine the protective effect of silkworm pupa oil on hydrochloric acid / ethanol-induced gastric ulcer." | 3.91 | Protective effect of silkworm pupa oil on hydrochloric acid/ethanol-induced gastric ulcers. ( Liu, X; Long, X; Suo, H; Wang, H; Wang, W; Zhang, Y; Zhao, X, 2019) |
| " Aiming to contribute in the scientific validation about the popular use of Brazilian Green propolis (BGP) against gastritis and gastric ulcer, this work evaluated the antiulcer potential of isolated compounds from BGP, three prenylated p-coumaric acid derivatives and two flavonoids, respectively named: 3,5 diprenyl-4-hydroxycinnamic acid (artepillin C) (1), 3-prenyl-4-dihydroxycinnamoiloxy cinnamic acid (baccharin) (2), 3-prenyl-4-hydroxycinnamic acid (drupanin) (3), aromadendrin-4'-O-methyl-ether (4) and kaempferide (5)." | 3.88 | Artepillin C, drupanin, aromadendrin-4'-O-methyl-ether and kaempferide from Brazilian green propolis promote gastroprotective action by diversified mode of action. ( Almeida, MO; Andrade, SF; Arruda, C; Bastos, JK; Boeing, T; Casoti, R; Costa, P; da Silva, LM; da Silva, RCMVAF; Dos Santos, AC; Lemos, M; Mariott, M; Somensi, LB; Souza, P; Stein, BP, 2018) |
| " Six scoparone derivatives were synthesized and screened for gastroprotective activities against HCl/ethanol- and indomethacin-induced gastric ulcers in rats." | 3.81 | Gastroprotective efficacy and safety evaluation of scoparone derivatives on experimentally induced gastric lesions in rodents. ( Choi, WS; Lee, GR; Lee, SE; Oh, S; Son, DJ, 2015) |
| " Treatment with MESe also decreased gastric ulceration induced by indomethacin." | 3.81 | Gastroprotective bio-guiding study of fruits from Mimusops balata. ( Boeing, T; Bordignon Somensi, L; de Moura Burci, L; Faloni de Andrade, S; Filho, VC; Mota da Silva, L; Santin, JR; Schlickmann, F, 2015) |
| "Zerumbone (1) showed potent cytoprotective effect against necrotizing agent (HCl) and non-steroidal anti-inflammatory drug (indomethacin) induced gastric ulceration." | 3.78 | Antiulcer principle from Zingiber montanum. ( Al-Amin, M; Hossain, CF; Sultana, GN, 2012) |
| " Acute gastric ulcer was induced using absolute ethanol, HCl/ethanol and indomethacin." | 3.77 | Antiulcerogenic activity of the essential oil of Hyptis martiusii Benth. (Lamiaceae). ( Caldas, GF; da Costa, JG; da Nóbrega, RF; da Silva, JB; do Amaral Costa, IM; Rodrigues, FF; Wanderley, AG, 2011) |
| ") significantly decreased ethanol- and indomethacin-induced gastric ulcer compared with the vehicle-treated (control) group." | 3.76 | Protective effects of a gastrointestinal agent containing Korean red ginseng on gastric ulcer models in mice. ( Hara, H; Kakino, M; Ogawa, K; Oyagi, A, 2010) |
| " This study aimed to determine the role of viable Lactobacillus in the healing of acetic acid-induced chronic gastric ulcer." | 3.76 | Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats. ( Kurakazu, K; Shimizu, K; Uchida, M, 2010) |
| "Lead increases the formation of gastric ulcers by interfering with the oxidative metabolism in the stomach." | 3.74 | Lead exposure increases oxidative stress in the gastric mucosa of HCl/ethanol-exposed rats. ( Adaramoye, OA; Adeniyi, OS; Erigbali, PP; Olaleye, SB, 2007) |
| " This study was designed to evaluate its gastroprotective effects on ethanol/HCl, indomethacin and pylorus ligation-induced gastric ulcers in rats." | 3.74 | Cytoprotective effects of Bergenia ciliata Sternb, extract on gastric ulcer in rats. ( Gulfraz, M; Kakub, G, 2007) |
| " In a chronic model, by acetic acid-induced gastric ulcers, COX-2 was expressed at 7 days and was also associated with PGE(2) increase." | 3.73 | COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions. ( Alarcón de la Lastra, C; Bruseghini, L; Manuel Herrerias, J; Motilva, V; Sánchez-Fidalgo, S, 2005) |
| "The gastroprotective activity of phytosphingosine hydrochloride (PS-HCl, CAS 554-62-1) was assessed in four different rat models of experimentally induced gastric ulcer." | 3.73 | Anti-ulcer actions of phytosphingosine hydrochloride in different experimental rat ulcer models. ( Baek, SW; Cho, MH; Jin, HJ; Kim, CK; Kim, JS; Kim, NK; Koh, CW; Kwon, OH; Park, CK, 2005) |
| "The gastroprotective effect of the sesquiterpene cyperenoic acid and seven semi-synthetic derivatives was assessed in the HCl/ethanol-induced gastric ulcer model in mice." | 3.73 | Gastroprotective activity and cytotoxic effect of cyperenoic acid derivatives. ( Pertino, M; Razmilic, I; Rodríguez, JA; Schmeda-Hirschmann, G; Theoduloz, C, 2006) |
| "To identify the pathogenesis of gastric ulcers by comparing injury to the nonglandular gastric mucosa of horses caused by hydrochloric acid (HCl) or volatile fatty acids (VFAs)." | 3.72 | Effects of hydrochloric, acetic, butyric, and propionic acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses. ( Andrews, FM; Argenzio, RA; Mathew, AG; Nadeau, JA; Patton, CS; Saxton, AM, 2003) |
| "The effects of beta-cyclodextrin (betaCD) inclusion complexation on the ability of violacein to prevent gastric ulceration in mice were studied." | 3.72 | Evaluation of the antiulcerogenic activity of violacein and its modulation by the inclusion complexation with beta-cyclodextrin. ( Almeida, AB; Brito, AR; De Azevedo, MB; Durán, N; Haun, M; Justo, GZ; Melo, PS, 2003) |
| "We investigated the effect of diacerein, an antiosteoarthritic agent, and its metabolite, rhein, on the production of reactive oxygen species (ROS) from neutrophils as well as the protective effect of diacerein on indomethacin-induced gastric ulceration and its protection mechanism." | 3.71 | Effects of diacerein on indomethacin-induced gastric ulceration. ( Ohmori, K; Tamura, T; Yokoyama, T, 2001) |
| "The effect of fenugreek seeds (Trigonella foenum graecum) compared to omeprazole was studied on ethanol-induced gastric ulcer." | 3.71 | Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats. ( Anuradha, CV; Pandian, RS; Viswanathan, P, 2002) |
| "The gastroprotective effect of the triterpene oleanolic acid (OA) was assessed on gastric ulceration in rats." | 3.71 | Gastroprotective activity of oleanolic acid derivatives on experimentally induced gastric lesions in rats and mice. ( Astudillo, L; Rodriguez, JA; Schmeda-Hirschmann, G, 2002) |
| "We investigated the effect of probucol, a lipid-lowering agent with antioxidant properties, on HCl plus ethanol-induced gastric mucosal injury and on the healing of acetic acid-induced gastric ulcers in rats." | 3.70 | Anti-ulcer effects of antioxidants: effect of probucol. ( Ishihara, M; Ito, M; Suzuki, Y, 1998) |
| "The results showed that Huanglion decoction has protective effect on ethanol-,HCl- and aspirin-induced gastric hemorrhagic lesions in rats and antemetic effect on CuSO4-induced vomiting in pigeons." | 3.69 | [Pharmacological studies on the effects of huanglian decoction on experimental gastric lesions in rats and antiemetic in pigeons]. ( Cheng, ZM; Liu, JY; Qin, CL, 1994) |
| "The present study was undertaken to determine the effect of a combination of selenium and vitamin E on stress and chemical-induced gastric ulcers in rats." | 3.69 | Effect of vitamin E and selenium on hypothermic restraint stress and chemically-induced ulcers. ( al-Moutairy, AR; Tariq, M, 1996) |
| " Water-immersion restraint stress- and aspirin-induced gastric ulcers were also significantly prevented in a dose-related manner by oral pretreatment with DS-4574 (10-50 mg/kg)." | 3.68 | Effect of DS-4574, a novel peptidoleukotriene antagonist with mast cell stabilizing action, on acute gastric lesions and gastric secretion in rats. ( Kurebayashi, Y; Tabuchi, Y, 1992) |
| "The role of oxygen-derived free radicals in the pathogenesis of acute gastric ulceration induced by indomethacin (Indo) was investigated in rats." | 3.68 | Role of oxygen-derived free radicals in indomethacin-induced gastric injury. ( Meddings, JB; Vaananen, PM; Wallace, JL, 1991) |
| "Levamisole, in doses similar to those required to observe immunostimulation in animals, antagonized dose-dependently, in rats, gastric ulcers produced by necrotizing agents (HCl and ethanol) and NSAIDs (indomethacin and piroxicam) without affecting the anti-inflammatory properties of these latter drugs." | 3.67 | The effect of levamisole on gastric ulcers induced in the rat by anti-inflammatory and necrotizing agents. ( Evangelista, S; Maggi, CA; Meli, A, 1984) |
| " Whereas gastric ulcers were produced by ulcerogenic agents including indomethacin, aspirin and reserpine, beside hypothermic restraint stress and by pylorus ligated Shay rat technique." | 3.67 | Gastroprotective activity of ginger zingiber officinale rosc., in albino rats. ( Ageel, AM; al-Yahya, MA; Mossa, JS; Parmar, NS; Rafatullah, S; Tariq, M, 1989) |
| "In order to explore secretory mechanisms in peptic ulcer, the plasma secretin response to an intraduodenal load of gastric acid stimulated with tetragastrin was studied in 10 patients with duodenal ulcer, nine with gastric ulcer, and five young healthy volunteers." | 3.66 | Effect of intraduodenal load of endogenous acid on secretin release in patients with peptic ulcer. ( Hamabe, S; Himeno, S; Kurokawa, M; Saito, R; Shima, K; Shinomura, Y; Takahashi, S; Tarui, S, 1982) |
| "Gastric ulcers were produced in conscious cats in 3 hr by simultaneous intravenous or intragastric administration of acetylsalicylic acid (ASA), plus intravenous infusion of histamine (80 micrograms/kg/hr), pentagastrin (8 micrograms/kg/hr), or intragastric instillation of HCl." | 3.66 | Aspirin-induced gastric ulcers in cats. Prevention by prostacyclin. ( Brzozowski, T; Dembińska-Kieć, A; Konturek, SJ; Piastucki, I; Radecki, T; Zmuda, A, 1981) |
| "In unanesthetized cats, continuous intravenous infusion of aspirin for 36 hr did not produce gastric ulcers when given alone but did when combined with 160 microgram kg-1 hr-1 of histamine-2HCl intravenously." | 3.66 | Histamine augments gastric ulceration produced by intravenous aspirin in cats. ( Aures, D; Grossman, MI; Hansen, DG, 1978) |
| " Smoking one cigarette significantly decreased the basal pyloric pressure, whereas 10 mg of metoclopramide as an intravenous bolus increased the pyloric pressure in normal subjects and in patients with gastric ulcer with low basal pressure." | 3.65 | Manometric studies on the human pyloric sphincter. Effect of cigarette smoking, metoclopramide, and atropine. ( Csendes, A; Defilippi, C; Valenzuela, JE, 1976) |
| " The extract was safe by oral route up to 2000 mg/kg in a single dose and NOAEL of 800 mg/kg in 28 days repeat study." | 1.51 | Preclinical development of gastro-protective botanical candidate from Woodfordia fruticosa (Linn.) Kurz: Chemical standardization, efficacy, pharmacokinetics and safety pharmacology. ( Gupta, AP; Gupta, P; Jaglan, S; Katare, AK; Khan, IA; Meena, S; Mindala, DP; Nandi, U; Roy, S; Singh, A; Singh, D; Singh, G; Singh, S; Tikko, MK; Vij, B; Vishwakarma, RA; Yadav, AK, 2019) |
| "Gastritis is preponderantly characterized by inflammation of the lining epithelial layer and the chronic gastritis is considered as a pre-cancer lesion." | 1.46 | Olive (Olea europaea) leaf methanolic extract prevents HCl/ethanol-induced gastritis in rats by attenuating inflammation and augmenting antioxidant enzyme activities. ( Abdel Moneim, AE; Al-Quraishy, S; Dkhil, MA; Othman, MS, 2017) |
| " Oral dosing with CFE at 250 and 500 mg/kg of body weight after the acid/alcohol induction significantly decreased the number of bleeding spots, area of bleeding, ulcer score, and ulcer index." | 1.36 | Protective effect of Cratoxylum formosum extract against acid/alcohol-induced gastric mucosal damage in rats. ( Sripanidkulchai, B; Sripanidkulchai, K; Teepsawang, S, 2010) |
| " EDE had gastroprotective effect related to increase of glutathione bioavailability and stimulated higher levels of NO, H2O2 and TNF-alpha production." | 1.35 | Davilla elliptica and Davilla nitida: gastroprotective, anti-inflammatory immunomodulatory and anti-Helicobacter pylori action. ( Bauab, TM; Brito, AR; Carlos, IZ; Hiruma-Lima, CA; Kushima, H; Nishijima, CM; Rinaldo, D; Rodrigues, CM; Sassá, MF; Stasi, LC; Vilegas, W, 2009) |
| "Pretreatment with beraprost attenuated AGML and downregulated the expression of HNE and HO-1, while sensory denervation aggravated AGML and upregulated the expression of HNE and HO-1." | 1.35 | Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions. ( Ichinose, M; Ito, T; Kimura, H; Oka, M; Shimizu, Y; Tsuruo, Y; Ueda, K; Ueyama, T; Yoshida, K, 2008) |
| "Kolaviron pre-treatment 1 h before ulcer induction attenuated the HCl/ethanol reduction in CAT, SOD and GSH by 43%, 42% and 30%, respectively, and 67%, 68% and 64% following 72 h treatment with kolaviron." | 1.33 | Attenuation of indomethacin- and HCl/ethanol-induced oxidative gastric mucosa damage in rats by kolaviron, a natural biflavonoid of Garcinia kola seed. ( Farombi, EO; Olaleye, SB, 2006) |
| "Pretreatment with omeprazole did not change the RX-77368 (15 ng)-induced increase in permeability, but quickened the recovery of permeability after the peak." | 1.33 | Evaluation of early gastric mucosal permeability induced by central thyrotropin-releasing hormone administration. ( Itoh, M; Joh, T; Kaneko, H; Kataoka, H; Nomura, T; Ohara, H; Oshima, T; Sasaki, M; Sobue, M; Suzuki, H; Takahashi, N; Watanabe, K, 2005) |
| " Despite the beneficial antiulcerogenic activity of DHC, our results suggest that the long-term use of this compound may induce liver damage." | 1.32 | Antiulcer activity and subacute toxicity of trans-dehydrocrotonin from Croton cajucara. ( Hiruma-Lima, CA; Rodríguez, JA; Souza Brito, AR, 2004) |
| " The present results suggest that the protective effects of lansoprazole can be ascribed to a reduction of gastric oxidative injury, resulting in an increased bioavailability of mucosal sulfhydryl compounds." | 1.32 | Mechanisms of gastroprotection by lansoprazole pretreatment against experimentally induced injury in rats: role of mucosal oxidative damage and sulfhydryl compounds. ( Blandizzi, C; Colucci, R; Del Tacca, M; Fornai, M; Lazzeri, G; Lubrano, V; Natale, G; Vassalle, C, 2004) |
| "Gastric acid is required for recurrence of gastric ulcers caused by IL-1beta, and gastric acid stimulates the inflammatory process in scarred mucosa during ulcer recurrence." | 1.31 | Acid regulates inflammatory response in a rat model of induction of gastric ulcer recurrence by interleukin 1beta. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Tominaga, K; Watanabe, T, 2001) |
| "The gastric toxic effects of aspirin (ASA) and NCX-4016, a nitric oxide (NO)-releasing ASA, were compared in normal, cirrhotic, and arthritic rats." | 1.31 | Low gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in rats with cirrhosis and arthritis. ( Kato, S; Komoike, Y; Suzuki, K; Takeuchi, K; Ukawa, H, 2001) |
| " Three h after dosing with 50 mg/kg acidified aspirin, there was superficial mucosal damage and decreased mucin content in the surface mucosal layer." | 1.30 | Recovery of mucin content in surface layer of rat gastric mucosa after HCl-aspirin-induced mucosal damage. ( Hotta, K; Ishihara, K; Saigenji, K; Sakai, T, 1997) |
| "Stomach ulcers were evaluated by morphological and histological examination." | 1.30 | Acid-induced gastric damage in rats is aggravated by starvation and prevented by several nutrients. ( Hung, CR; Neu, SL, 1997) |
| "Pretreatment with glycine significantly protected animals against stress-, indomethacin- and necrotizing agents induced gastric lesions." | 1.30 | Studies on the antisecretory, gastric anti-ulcer and cytoprotective properties of glycine. ( Al Moutaery, AR; Tariq, M, 1997) |
| " Hourly dosing with hydrochloric acid reversed the protective effect of ranitidine, cimetidine and loxtidine on macroscopic damage and, histologically, this was associated with the widespread appearance of antral ulcers and a reduction in the proportion of mucosal damage caused by superficial erosions." | 1.29 | The role of acid in the pathogenesis of indomethacin-induced gastric antral ulcers in the rat. ( Clayton, NM; Oakley, I; Trevethick, MA; Williams, LV, 1996) |
| "It is concluded that respiratory acidosis could be involved in stress ulceration." | 1.28 | Does acidosis contribute to stress-induced ulceration in rat stomachs? ( Cho, CH; Koo, MW; Ogle, CW, 1989) |
| ") given 30 min prior to SU-88 dosing blocked this protective effect, whereas it was not affected when indomethacin was given 30 min after the SU-88 dosing." | 1.27 | Cytoprotective effect of SU-88, an anti-ulcer agent, in the rat. ( Kyogoku, K; Mori, Y; Nakazima, M; Shinozaki, A; Suwa, T, 1984) |
| "pretreatment with indomethacin (5 mg/kg, s." | 1.27 | Cytoprotective effects of NC-1300 and omeprazole on Hcl . ethanol-induced gastric lesions in rats. ( Awane, Y; Miyake, H; Okabe, S, 1986) |
| "Gastric stress ulcers were produced by restraint in nonsecretory rats, and the response of the ulcer index to intraduodenal hydrochloric acid (HCl) or sodium chloride (NaCl) was studied in a three-step dose-response trial." | 1.26 | Gastric stress ulcers and gastrointestinal hormones - response to hydrochloric acid and sodium chloride infused intraduodenally. Preliminary report. ( Bloom, SR; Draxler, G; Engelhardt, W; Putz, FJ; Schwille, PO, 1980) |
| " In animals pretreated by anti-inflammatory drugs in toxic doses an earlier development of ulceration was observed by distention with acid." | 1.26 | Distention ulcer as a model for testing of drugs for ulcerogenic side effects. ( Szelenyi, I; Thiemer, K, 1978) |
| "When hydrochloric acid (0." | 1.26 | Acidification of arterial blood enhances gastric mucosal injury induced by bile salts in dogs. ( Cheung, LY; Sonnenschein, LA; Toenjes, AA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 86 (35.68) | 18.7374 |
| 1990's | 48 (19.92) | 18.2507 |
| 2000's | 60 (24.90) | 29.6817 |
| 2010's | 42 (17.43) | 24.3611 |
| 2020's | 5 (2.07) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 2 |
| Sun, L | 1 |
| Lai, X | 1 |
| Peng, X | 1 |
| Wen, S | 1 |
| Zhang, Z | 1 |
| Xie, Y | 1 |
| Li, Q | 1 |
| Chen, R | 1 |
| Zheng, X | 1 |
| Zhang, K | 1 |
| Sun, S | 1 |
| Li, D | 1 |
| Kwon, SC | 1 |
| Kim, JH | 1 |
| Djebli, N | 1 |
| Mustafa, MR | 1 |
| Keskin, M | 1 |
| Kolayli, S | 1 |
| Boeing, T | 4 |
| Mejía, JAA | 1 |
| Ccana-Ccapatinta, GV | 1 |
| Mariott, M | 2 |
| Melo Vilhena de Andrade Fonseca Da Silva, RC | 1 |
| de Souza, P | 1 |
| Mariano, LNB | 1 |
| Oliveira, GR | 1 |
| da Rocha, IM | 1 |
| da Costa, GA | 1 |
| de Andrade, SF | 4 |
| da Silva, LM | 2 |
| Bastos, JK | 2 |
| Wang, R | 1 |
| Sun, F | 1 |
| Ren, C | 1 |
| Zhai, L | 1 |
| Xiong, R | 1 |
| Yang, Y | 1 |
| Yang, W | 1 |
| Yi, R | 1 |
| Li, C | 1 |
| Zhao, X | 3 |
| Al-Quraishy, S | 1 |
| Othman, MS | 1 |
| Dkhil, MA | 1 |
| Abdel Moneim, AE | 1 |
| Yang, HJ | 1 |
| Kim, MJ | 1 |
| Kwon, DY | 1 |
| Kang, ES | 1 |
| Kang, S | 1 |
| Park, S | 1 |
| Tayeby, F | 1 |
| Salman, AAA | 1 |
| Kamran, S | 1 |
| Khaing, SL | 1 |
| Salehen, NB | 1 |
| Mohan, GMAD | 1 |
| Hamdi, A | 2 |
| Majouli, K | 2 |
| Abdelhamid, A | 2 |
| Marzouk, B | 1 |
| Belghith, H | 1 |
| Chraief, I | 1 |
| Bouraoui, A | 4 |
| Marzouk, Z | 1 |
| Heyden, YV | 1 |
| Kenani, A | 1 |
| Yoo, JH | 1 |
| Lee, JS | 1 |
| Lee, YS | 1 |
| Ku, S | 1 |
| Lee, HJ | 1 |
| Sahin, HH | 1 |
| Cumbul, A | 1 |
| Uslu, U | 1 |
| Yilmaz, Z | 1 |
| Ercan, F | 1 |
| Alican, I | 1 |
| Costa, P | 1 |
| Almeida, MO | 1 |
| Lemos, M | 4 |
| Arruda, C | 1 |
| Casoti, R | 1 |
| Somensi, LB | 2 |
| da Silva, RCMVAF | 1 |
| Stein, BP | 1 |
| Souza, P | 1 |
| Dos Santos, AC | 1 |
| Andrade, SF | 1 |
| Long, X | 1 |
| Wang, W | 1 |
| Wang, H | 1 |
| Liu, X | 1 |
| Suo, H | 2 |
| Bang, BW | 1 |
| Park, D | 1 |
| Kwon, KS | 1 |
| Lee, DH | 1 |
| Jang, MJ | 1 |
| Park, SK | 1 |
| Kim, JY | 1 |
| Khan, IA | 1 |
| Singh, A | 1 |
| Mindala, DP | 1 |
| Meena, S | 1 |
| Vij, B | 1 |
| Yadav, AK | 1 |
| Roy, S | 1 |
| Nandi, U | 1 |
| Katare, AK | 1 |
| Jaglan, S | 1 |
| Singh, D | 1 |
| Gupta, AP | 1 |
| Gupta, P | 1 |
| Singh, S | 2 |
| Tikko, MK | 1 |
| Singh, G | 1 |
| Vishwakarma, RA | 1 |
| Klein-Júnior, LC | 1 |
| Santin, JR | 3 |
| Silveira, AC | 1 |
| Rocha, JA | 1 |
| Beber, AP | 1 |
| Wagner, TM | 1 |
| Bresolin, TM | 1 |
| Bella-Cruz, A | 1 |
| Cechinel-Filho, V | 1 |
| Faloni de Andrade, S | 2 |
| Jesus, NZ | 1 |
| Falcão, HS | 1 |
| Lima, GR | 1 |
| Caldas Filho, MR | 1 |
| Sales, IR | 1 |
| Gomes, IF | 1 |
| Santos, SG | 1 |
| Tavares, JF | 1 |
| Barbosa-Filho, JM | 1 |
| Batista, LM | 2 |
| Amang, PA | 1 |
| Tan, PV | 1 |
| Patamaken, SA | 1 |
| Mefe, MN | 1 |
| Prado, LC | 1 |
| Silva, DB | 1 |
| de Oliveira-Silva, GL | 1 |
| Hiraki, KR | 1 |
| Canabrava, HA | 1 |
| Bispo-da-Silva, LB | 1 |
| Martins, JL | 1 |
| Rodrigues, OR | 1 |
| da Silva, DM | 1 |
| Galdino, PM | 1 |
| de Paula, JR | 1 |
| Romão, W | 2 |
| da Costa, HB | 1 |
| Vaz, BG | 1 |
| Ghedini, PC | 1 |
| Costa, EA | 1 |
| Deghrigue, M | 1 |
| Festa, C | 1 |
| Ghribi, L | 1 |
| D'auria, MV | 1 |
| de Marino, S | 1 |
| Ben Jannet, H | 1 |
| Ben Said, R | 2 |
| Taketani, Y | 1 |
| Kinugasa, K | 1 |
| Kitajima, R | 1 |
| Nishiumi, S | 1 |
| Ashida, H | 1 |
| Nakamura, H | 2 |
| Fujita, T | 1 |
| Kanzaki, K | 1 |
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3 reviews available for hydrochloric acid and Stomach Ulcer
| Article | Year |
|---|---|
GASTRIC SECRETORY ACTIVITY WITH REFERENCE TO HCL. CLINICAL INTERPRETATIONS.
Topics: Anemia; Anemia, Pernicious; Blood Group Antigens; Duodenal Ulcer; Electrolytes; Gastric Acidity Dete | 1964 |
[The problem of proteolysis in the stomach after discovery of the new pepsins].
Topics: Agar; Amino Acid Sequence; Animals; Buffers; Carcinoma; Cathepsins; Chemical Phenomena; Chemistry; C | 1971 |
[Achievements of the intragastric pH measurement technic].
Topics: Electronics, Medical; Gastrectomy; Gastric Acidity Determination; Gastric Juice; Gastroscopy; Humans | 1970 |
2 trials available for hydrochloric acid and Stomach Ulcer
| Article | Year |
|---|---|
Controlled trials of aluminum hydroxide gels for peptic ulcer.
Topics: Aluminum Hydroxide; Analgesia; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer; Humans; Hy | 1977 |
Test for H2-antagonist response in non-ulcer dyspepsia.
Topics: Adolescent; Adult; Antacids; Citrates; Citric Acid; Clinical Trials as Topic; Drug Evaluation; Dyspe | 1990 |
236 other studies available for hydrochloric acid and Stomach Ulcer
| Article | Year |
|---|---|
Gastroprotective effects of extract of Jasminum grandiflorum L. flower in HCl/EtOH-induced gastric mucosal ulceration mice.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Apoptosis Regulatory Proteins; D | 2021 |
Gastroprotective effects of irsogladine maleate on ethanol/hydrochloric acid induced gastric ulcers in mice.
Topics: Animals; Ethanol; Gastric Mucosa; Hydrochloric Acid; Mice; Stomach Ulcer; Triazines | 2021 |
Anti-Ulcerogenic and Cytoprotective Effects of Saharian (Sidr) Honey from Algeria.
Topics: Algeria; Animals; Anti-Ulcer Agents; Antioxidants; Biphenyl Compounds; Ethanol; Flavonoids; Gastric | 2021 |
The gastroprotective effect of red propolis extract from Northeastern Brazil and the role of its isolated compounds.
Topics: Animals; Anti-Ulcer Agents; Brazil; Disease Models, Animal; Ethanol; Gastric Acid; Gastric Mucins; G | 2021 |
Hunan insect tea polyphenols provide protection against gastric injury induced by HCl/ethanol through an antioxidant mechanism in mice.
Topics: Animals; Antioxidants; Beverages; Ethanol; Gastric Juice; Hydrochloric Acid; Insecta; Mice; Polyphen | 2021 |
Olive (Olea europaea) leaf methanolic extract prevents HCl/ethanol-induced gastritis in rats by attenuating inflammation and augmenting antioxidant enzyme activities.
Topics: Animals; Antioxidants; Body Weight; Chromatography, High Pressure Liquid; Ethanol; Gastritis; Hydroc | 2017 |
Gastroprotective actions of Taraxacum coreanum Nakai water extracts in ethanol-induced rat models of acute and chronic gastritis.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Ethanol; Flavonoids; Gastric Muc | 2017 |
Ulcer Prevention Effect Of 3,4,5-Tihydroxy-N0-[(2-Methyl-1H-Indol-3yl)Methylidene]Benzohydrazide In HCl/Ethanol-Induced Gastric Mucosal Damage In Rats.
Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Disease Models, Animal; Ethanol; Gallic Acid; Gas | 2017 |
Pharmacological activities of the organic extracts and fatty acid composition of the petroleum ether extract from Haplophyllum tuberculatum leaves.
Topics: Acetic Acid; Alkanes; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; | 2018 |
Anti-inflammatory activity and gastroprotective effect of Hertia cheirifolia L. roots extract.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Asteraceae; Carrageenan; Disease Models, Anima | 2018 |
Protective effect of bovine milk against HCl and ethanol-induced gastric ulcer in mice.
Topics: Animals; Anti-Ulcer Agents; Catalase; Cattle; Ethanol; Gastric Mucosa; Humans; Hydrochloric Acid; Ma | 2018 |
The effect of 1,25 dihydroxyvitamin D3 on HCl/Ethanol-induced gastric injury in rats.
Topics: Animals; Antioxidants; Apoptosis; Calcitriol; Ethanol; Gastric Mucosa; Hydrochloric Acid; Oxidative | 2018 |
Artepillin C, drupanin, aromadendrin-4'-O-methyl-ether and kaempferide from Brazilian green propolis promote gastroprotective action by diversified mode of action.
Topics: Animals; Anti-Ulcer Agents; Cinnamates; Ethanol; Flavonoids; Hydrochloric Acid; Indomethacin; Kaempf | 2018 |
Protective effect of silkworm pupa oil on hydrochloric acid/ethanol-induced gastric ulcers.
Topics: Animals; Antioxidants; Bombyx; Catalase; Ethanol; Fatty Acids, Unsaturated; Female; Glutathione Pero | 2019 |
BST-104, a Water Extract of Lonicera japonica, Has a Gastroprotective Effect via Antioxidant and Anti-Inflammatory Activities.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Chlorogenic Acid; C | 2019 |
Preclinical development of gastro-protective botanical candidate from Woodfordia fruticosa (Linn.) Kurz: Chemical standardization, efficacy, pharmacokinetics and safety pharmacology.
Topics: Animals; Anti-Ulcer Agents; Ethanol; Female; Flowers; Helicobacter pylori; Hydrochloric Acid; Male; | 2019 |
Role of gastric mucus secretion, oxinitrergic system and sulfhydryl groups on the gastroprotection elicited by Polygala cyparissias (Polygalaceae) in mice.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Chronic Disease; Ethanol; Gastric Mucosa; Helicobacter pylo | 2013 |
Hyptis suaveolens (L.) Poit (Lamiaceae), a medicinal plant protects the stomach against several gastric ulcer models.
Topics: Animals; Ethanol; Gastric Mucosa; Hydrochloric Acid; Hyptis; Ligation; Male; Phytotherapy; Piroxicam | 2013 |
Cytoprotective and antioxidant effects of the methanol extract of Eremomastax speciosa in rats.
Topics: Acanthaceae; Animals; Anti-Ulcer Agents; Antioxidants; Catalase; Cold Temperature; Ethanol; Gastric | 2014 |
The gastroprotective effects of Eugenia dysenterica (Myrtaceae) leaf extract: the possible role of condensed tannins.
Topics: Animals; Anti-Ulcer Agents; Carbenoxolone; Ethanol; Free Radical Scavengers; Gastric Mucosa; Hydroch | 2014 |
Mechanisms involved in the gastroprotective activity of Celtis iguanaea (Jacq.) Sargent on gastric lesions in mice.
Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Animals; Anti-Ulcer Agents; Cyclooxygenase Inh | 2014 |
Pharmacological evaluation of the semi-purified fractions from the soft coral Eunicella singularis and isolation of pure compounds.
Topics: Animals; Anthozoa; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; Disease Models, Animal; | 2014 |
Protective effects of oral administration of yeast thioredoxin against gastric mucosal injury.
Topics: Administration, Oral; Animals; Cell Line; Cytoprotection; Digestion; Ethanol; Fermentation; Gastric | 2014 |
Physico-chemical characterization and pharmacological evaluation of sulfated polysaccharides from three species of Mediterranean brown algae of the genus Cystoseira.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Disease Models, Animal; Dose-Response | 2015 |
Gastroprotective efficacy and safety evaluation of scoparone derivatives on experimentally induced gastric lesions in rodents.
Topics: Alanine; Animals; Anti-Ulcer Agents; Artemisia; Coumarins; Ethanol; Hydrochloric Acid; Indomethacin; | 2015 |
Gastroprotective bio-guiding study of fruits from Mimusops balata.
Topics: Animals; Anti-Ulcer Agents; Ethanol; Female; Free Radical Scavengers; Fruit; Gastric Mucosa; Glutath | 2015 |
Investigation of Antiulcer and Antioxidant Activity of Juniperus phoenicea L. (1753) Essential Oil in an Experimental Rat Model.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Bicyclic Monoterpenes; Catalase; Disease Models, Animal; E | 2015 |
Gastroprotective effect of aqueous stem bark extract of Ziziphus jujuba L. against HCl/Ethanol-induced gastric mucosal injury in rats.
Topics: Animals; Anti-Bacterial Agents; Drugs, Chinese Herbal; Ethanol; Female; Gastric Mucosa; Helicobacter | 2015 |
Lactobacillus fermentum Suo Attenuates HCl/Ethanol Induced Gastric Injury in Mice through Its Antioxidant Effects.
Topics: Animals; Antioxidants; Cytokines; Disease Models, Animal; Ethanol; Gastric Juice; Gastric Mucosa; Ga | 2016 |
Gastroprotective effects of new diterpenoid derivatives from Azorella cuatrecasasii Mathias & Constance obtained using a β-cyclodextrin complex with microbial and chemical transformations.
Topics: Alcohols; Animals; Anti-Ulcer Agents; Apiaceae; beta-Cyclodextrins; Disease Models, Animal; Diterpen | 2016 |
A Zinc Morpholine Complex Prevents HCl/Ethanol-Induced Gastric Ulcers in a Rat Model.
Topics: Animals; Cell Line; Disease Models, Animal; DNA Damage; Ethanol; Humans; Hydrochloric Acid; Hydrogen | 2016 |
Gastroprotective activity of the resin from Virola oleifera.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Benzothiazoles; Chromatography, Thin Layer; Disease Models | 2017 |
Gastroprotective and anti-secretory mechanisms of 2-phenylquinoline, an alkaloid isolated from Galipea longiflora.
Topics: Alkaloids; Animals; Anti-Ulcer Agents; Antioxidants; Ethanol; Gastric Acid; Gastric Juice; Gastric M | 2017 |
Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions.
Topics: Adaptation, Physiological; Aldehydes; Animals; Capsaicin; Cytoprotection; Denervation; Disease Model | 2008 |
Antiulcerogenic action of ethanolic extract of the resin from Virola surinamensis Warb. (Myristicaceae).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Catechin; Cimetidine; Cold Temp | 2009 |
Gastroprotective activity of alkaloid extract and 2-phenylquinoline obtained from the bark of Galipea longiflora Krause (Rutaceae).
Topics: Alkaloids; Animals; Anti-Ulcer Agents; Bethanechol; Dose-Response Relationship, Drug; Ethanol; Hydro | 2009 |
Davilla elliptica and Davilla nitida: gastroprotective, anti-inflammatory immunomodulatory and anti-Helicobacter pylori action.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 2009 |
Anti-ulcer role of herbomineral Siddha drug - Thamira parpam on experimentally induced gastric mucosal damage in rats.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Body Weight; Cytoprotection; Disease Models, Anim | 2010 |
Antiulcerogenic activity of extract, fractions, and some compounds obtained from Polygala cyparissias St. Hillaire & Moquin (Polygalaceae).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bethanechol; Dose-Response Rela | 2010 |
Anti-ulcerogenic effect and HPLC analysis of the caffeoylquinic acid-rich extract from Ligularia stenocephala.
Topics: Animals; Anti-Ulcer Agents; Asteraceae; Bethanechol; Chromatography, High Pressure Liquid; Ethanol; | 2010 |
Protective effects of a gastrointestinal agent containing Korean red ginseng on gastric ulcer models in mice.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Ga | 2010 |
Protective effect of Cratoxylum formosum extract against acid/alcohol-induced gastric mucosal damage in rats.
Topics: Animals; Clusiaceae; Ethanol; Gastric Mucosa; Hydrochloric Acid; Male; Malondialdehyde; Plant Extrac | 2010 |
Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Dinoprostone; Gamma Rays; Gastric Mucosa; Hydrochloric Acid; Lactobacillus; Pr | 2010 |
Massive necrosis of the upper gastrointestinal tract with acute gastric perforation and metabolic acidosis after hydrochloric acid (HCl) ingestion.
Topics: Abdomen, Acute; Acidosis; Burns, Chemical; Esophagectomy; Esophagus; Fatal Outcome; Female; Gastrect | 2011 |
Gastroprotective activity of Zanthoxylum rhoifolium Lam. in animal models.
Topics: Animals; Anti-Ulcer Agents; Catalase; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Eth | 2011 |
Antiulcerogenic activity of the essential oil of Hyptis martiusii Benth. (Lamiaceae).
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gas C | 2011 |
Selective histamine H₃ and H₄ receptor agonists exert opposite effects against the gastric lesions induced by HCl in the rat stomach.
Topics: Animals; HEK293 Cells; Histamine Agonists; Histamine Antagonists; Humans; Hydrochloric Acid; Male; P | 2011 |
Gastroprotective activity of epitaondiol and sargaol.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Ethanol; Hydrochloric Acid; Lan | 2011 |
Gastric cytoprotection and honey intake in albino rats.
Topics: Albinism; Animals; Anti-Ulcer Agents; Cytoprotection; Disease Models, Animal; Gastric Mucosa; Honey; | 2011 |
Gastro-protective effect of crude hexane leaf extract of Sesamum indicum in rabbits.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cytoprotection; Disease Models, Animal; Dose-Response Relati | 2011 |
Antiulcer principle from Zingiber montanum.
Topics: Animals; Anti-Ulcer Agents; Chromatography; Cytoprotection; Disease Models, Animal; Dose-Response Re | 2012 |
Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats.
Topics: Animals; Ethanol; Gastric Mucosa; Hydrochloric Acid; Lipid Peroxidation; Omeprazole; Phytotherapy; P | 2002 |
Role of acid back-diffusion, glutathione, oxyradical, and histamine in antral hemorrhagic ulcer in rats: the protective effect of lysozyme chloride and antioxidants.
Topics: Animals; Antioxidants; Diffusion; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric | 2002 |
Effects of Anethum graveolens L. seed extracts on experimental gastric irritation models in mice.
Topics: Anethum graveolens; Animals; Anti-Ulcer Agents; Disease Models, Animal; Gastric Acid; Hydrochloric A | 2002 |
Effects of hydrochloric, acetic, butyric, and propionic acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses.
Topics: Acetic Acid; Animals; Butyric Acid; Culture Techniques; Fatty Acids, Volatile; Female; Gastric Mucos | 2003 |
Effects of hydrochloric, valeric, and other volatile fatty acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses.
Topics: Animals; Culture Techniques; Electric Conductivity; Fatty Acids, Volatile; Female; Horse Diseases; H | 2003 |
Protective effects of polygodial on gastric mucosal lesions induced by necrotizing agents in rats and the possible mechanisms of action.
Topics: Animals; Aspirin; Ethanol; Gastric Mucosa; Gastrointestinal Agents; Hydrochloric Acid; Indomethacin; | 2003 |
Evaluation of the antiulcerogenic activity of violacein and its modulation by the inclusion complexation with beta-cyclodextrin.
Topics: Animals; Anti-Ulcer Agents; Cells, Cultured; Chemistry, Pharmaceutical; Cimetidine; Cyclodextrins; D | 2003 |
[The multiplicity of extragstric sources of hydrochloric stimulation of the stomach, with direct action on the parietal cells. Significance for the surgical treatment of gastic ulcer].
Topics: Gastrectomy; Gastric Juice; Hydrochloric Acid; Stomach Ulcer; Ulcer | 1962 |
[PHYSIOPATHOLOGY OF HYDROCHLORIC ACID SECRETION. THE TEST OF MAXIMAL STIMULATION WITH HISTAMINE].
Topics: Achlorhydria; Gastric Acidity Determination; Gastric Juice; Histamine; Humans; Hydrochloric Acid; Pe | 1963 |
EFFECTS OF GASTRIC FREEZING ON THE ISOLATED DENERVATED GASTRIC POUCH IN DOGS.
Topics: Animals; Cats; Cryosurgery; Dogs; Freezing; Gastric Acidity Determination; Gastric Fistula; Gastric | 1964 |
ESTIMATION OF GASTRIC PEPSIN IN THE DIAGNOSIS OF PEPTIC ULCER.
Topics: Biomedical Research; Chlorides; Clinical Laboratory Techniques; Duodenal Ulcer; Gastric Juice; Human | 1964 |
THE RECURRENCE OF ULCERATION AFTER SURGERY FOR DUODENAL ULCER.
Topics: Alcoholism; Duodenal Ulcer; Gastrectomy; Gastric Acidity Determination; Gastroenterostomy; Humans; H | 1964 |
DIFFERENTIAL TASTE SENSITIVITIES IN DUODENAL AND GASTRIC ULCER PATIENTS.
Topics: Biomedical Research; Black People; Duodenal Ulcer; Duodenum; Humans; Hydrochloric Acid; Propylthiour | 1964 |
Gastric inflammation triggers hypersensitivity to acid in awake rats.
Topics: Animals; Capsaicin; Catheterization; Denervation; Electromyography; Gastritis; Gastrointestinal Moti | 2003 |
Gastroprotective and anti-inflammatory effects of resin from Protium heptaphyllum in mice and rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Brazil; Burseraceae; Capillary Pe | 2004 |
Mucosal damage induced by preferential COX-1 and COX-2 inhibitors: role of prostaglandins and inflammatory response.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; D | 2004 |
Prevention of experimentally-induced gastric ulcers in rats by an ethanolic extract of "Parsley" Petroselinum crispum.
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Ethanol; Gastric Mucosa; Hydrochloric Acid; Hypo | 2003 |
The gastroprotective effect of tannins extracted from duhat (Syzygium cumini Skeels) bark on HCl/ethanol induced gastric mucosal injury in Sprague-Dawley rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Dose-Response Rel | 2003 |
The clinical significance of the small benign gastric ulcer with a note on benign ulcer of the greater curvature and in the absence of free hydrochloric acid.
Topics: Humans; Hydrochloric Acid; Peptic Ulcer; Stomach Ulcer; Ulcer | 1952 |
Mechanisms of gastroprotection by lansoprazole pretreatment against experimentally induced injury in rats: role of mucosal oxidative damage and sulfhydryl compounds.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Cyclooxygenase 1; Cyclooxygenas | 2004 |
Anti-ulcerogenic effect of chitin and chitosan on mucosal antioxidant defence system in HCl-ethanol-induced ulcer in rats.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Catalase; Chitin; Chitosan; Ethanol; Gastric Juice; Gastri | 2004 |
Sensitization of mechanosensitive gastric vagal afferent fibers in the rat by thermal and chemical stimuli and gastric ulcers.
Topics: Animals; Gastric Mucosa; Glycocholic Acid; Hot Temperature; Hydrochloric Acid; Hydrogen-Ion Concentr | 2004 |
Protective role of vanilloid receptor type 1 in HCl-induced gastric mucosal lesions in rats.
Topics: Acetamides; Animals; Anti-Ulcer Agents; Capsaicin; Catechols; Diterpenes; Famotidine; Fatty Alcohols | 2004 |
Efficacy of brown seaweed hot water extract against HCl-ethanol induced gastric mucosal injury in rats.
Topics: Animals; Ethanol; Gastric Mucosa; Hot Temperature; Hydrochloric Acid; Male; Plant Extracts; Rats; Ra | 2004 |
Evaluation of the gastric antiulcerogenic effects of Portulaca oleracea L. extracts in mice.
Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Ethanol; Hydrochloric Acid; Male; Medi | 2004 |
Effects of celecoxib on acid-challenged gastric mucosa of rats: comparison with metamizol and piroxicam.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase | 2004 |
The anti-gastric ulcer effect of Gynostemma pentaphyllum Makino.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Ethanol; Gastric | 2004 |
Antiulcer activity and subacute toxicity of trans-dehydrocrotonin from Croton cajucara.
Topics: Alkaline Phosphatase; Animals; Anti-Ulcer Agents; Chemical and Drug Induced Liver Injury; Cholestero | 2004 |
Evaluation of early gastric mucosal permeability induced by central thyrotropin-releasing hormone administration.
Topics: Animals; Anti-Ulcer Agents; Atropine; Brain; Gastric Mucosa; Hydrochloric Acid; Injections, Intraven | 2005 |
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions.
Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge | 2005 |
Lipid compositions of human gastric fluid and epithelium: the role of sulfated lipids in gastric cytoprotection.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anticarcinogenic Agents; Cholesterol Esters; Chromatography | 2005 |
Gastroprotective activity of a new semi-synthetic solidagenone derivative in mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Animals; Anti-Ulcer Agents; Cell Line | 2005 |
Anti-ulcerogenic activity of xanthanolide sesquiterpenes from Xanthium cavanillesii in rats.
Topics: Animals; Anti-Ulcer Agents; Central Nervous System Depressants; Chemical Phenomena; Chemistry, Physi | 2005 |
Anti-ulcer actions of phytosphingosine hydrochloride in different experimental rat ulcer models.
Topics: Animals; Anti-Ulcer Agents; Central Nervous System Depressants; Cysteamine; Duodenal Ulcer; Ethanol; | 2005 |
Gastroprotective and ulcer healing effect of ferruginol in mice and rats: assessment of its mechanism of action using in vitro models.
Topics: Abietanes; Acetic Acid; Animals; Anti-Ulcer Agents; Biphenyl Compounds; Cell Line; Cell Survival; Di | 2006 |
Attenuation of indomethacin- and HCl/ethanol-induced oxidative gastric mucosa damage in rats by kolaviron, a natural biflavonoid of Garcinia kola seed.
Topics: Animals; Catalase; Flavonoids; Garcinia kola; Gastric Mucosa; Glutathione; Hydrochloric Acid; Incide | 2006 |
Can the aqueous decoction of mango flowers be used as an antiulcer agent?
Topics: Animals; Anti-Ulcer Agents; Cyclooxygenase Inhibitors; Ethanol; Ethylmaleimide; Flavonoids; Flowers; | 2006 |
Effect of Mouriri pusa extracts on experimentally induced gastric lesions in rodents: role of endogenous sulfhydryls compounds and nitric oxide in gastroprotection.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Brazil; Enzyme Inhibitors; Etha | 2006 |
Gastroprotective and ulcer-healing activity of oleanolic acid derivatives: in vitro-in vivo relationships.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Cell Line; Cell Proliferation; | 2006 |
Effects of sucralfate, cimetidine and rabeprazole on mucosal hydroxyproline content in healing of ethanol-hcl-induced gastric lesions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Cimetidine; Ethanol; Gastric Mu | 2006 |
Gastroprotective activity and cytotoxic effect of cyperenoic acid derivatives.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Cell Line; Cell Survival; Disease Models, Animal; | 2006 |
Genetic evidence for a protective role of heat shock factor 1 against irritant-induced gastric lesions.
Topics: Animals; Apoptosis; Cells, Cultured; Diterpenes; DNA-Binding Proteins; Ethanol; Gastric Mucosa; Heat | 2007 |
Antiulcerogenic activity of Zizyphus lotus (L.) extracts.
Topics: Animals; Anti-Ulcer Agents; Ethanol; Female; Fruit; Hydrochloric Acid; Male; Plant Bark; Plant Extra | 2007 |
Gastroprotective effect and cytotoxicity of labdenamides.
Topics: Animals; Anti-Ulcer Agents; Cells, Cultured; Disease Models, Animal; Diterpenes; Dose-Response Relat | 2007 |
Cytoprotective effects of Bergenia ciliata Sternb, extract on gastric ulcer in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cytoprotection; Ethanol; Hydroc | 2007 |
Lead exposure increases oxidative stress in the gastric mucosa of HCl/ethanol-exposed rats.
Topics: Animals; Catalase; Ethanol; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Hydrochloric Ac | 2007 |
Prophylactic effect of lafutidine against the adverse reaction induced in rat stomach by repeated administration of 5-fluorouracil.
Topics: Acetamides; Animals; Anti-Ulcer Agents; Cimetidine; Dinoprostone; Drug Interactions; Fluorouracil; G | 2007 |
Anti-ulcerogenic effects of the flavonoid-rich fraction from the extract of Orostachys japonicus in mice.
Topics: Analgesia; Analgesics; Animals; Bethanechol; Crassulaceae; Flavonoids; Gastric Juice; Hydrochloric A | 2007 |
In vitro effects of hydrochloric and lactic acids on bioelectric properties of equine gastric squamous mucosa.
Topics: Animals; Dose-Response Relationship, Drug; Electric Conductivity; Electric Impedance; Fatty Acids, V | 2008 |
The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Boswellia; Ethanol; Hot Temperature; Hydrochloric Acid; Indomet | 2008 |
Gastric mucoproteins in dogs and man. Effects of steroids.
Topics: Animals; Cortisone; Denervation; Dogs; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; | 1967 |
[Clinical value of the maximal histamine test in association with conservative vagotomy].
Topics: Adolescent; Adult; Aged; Female; Gastric Acidity Determination; Gastritis; Histamine; Humans; Hydroc | 1967 |
The gastric fundic mucosal energy systems and the HCl-induced lesions in rats in dependence on starvation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Energy | 1984 |
Effects of cimetidine administered in cytoprotective and antisecretory doses on the membrane-bound ATP-dependent energy systems in the gastric mucosal lesions induced by HCl in rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Cyclases; Animals | 1984 |
Interrelationships between the membrane-bound ATP-dependent energy systems of the gastric mucosa and the gastric cytoprotective effect of beta-carotene on the development of gastric mucosal damage produced by 0.6 M HCl in rats.
Topics: Adenosine Triphosphate; Animals; beta Carotene; Carotenoids; Cell Membrane; Cyclic AMP; Dose-Respons | 1984 |
Gastric cytoprotection by prostaglandins, ranitidine, and probanthine in rats. Role of endogenous prostaglandins.
Topics: Animals; Aspirin; Epoprostenol; Furans; Gastric Juice; Gastric Mucosa; Histamine H2 Antagonists; Hyd | 1981 |
Aspirin-induced gastric ulcers in cats. Prevention by prostacyclin.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cats; Epoprostenol; Furans; Gastric Acid; Histamine; Histamine | 1981 |
The effect of levamisole on gastric ulcers induced in the rat by anti-inflammatory and necrotizing agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Ethanol; Hydrochloric Acid; Indomethacin; Leva | 1984 |
Effects of capsaicin on the development of gastric mucosal damage by different necrotizing agents and of gastric cytoprotection by PGI2 atropine and cimetidine on rats.
Topics: Animals; Atropine; Capsaicin; Cimetidine; Epoprostenol; Ethanol; Female; Gastric Mucosa; Hydrochlori | 1984 |
Interrelationships between the development of the gastric cytoprotective effects of prostacyclin, atropine, cimetidine and the gastric mucosal superoxide dismutase activity in rats.
Topics: Animals; Atropine; Cimetidine; Epoprostenol; Ethanol; Female; Gastric Mucosa; Hydrochloric Acid; Mal | 1984 |
Local fibrinolytic activity and its structural basis in experimental gastric ulcers.
Topics: Animals; Fibrinolysis; Gastric Mucosa; Hydrochloric Acid; Male; Microscopy, Electron, Scanning; Plas | 1983 |
Contribution of ambient HCO3- to mucosal protection and intracellular pH in isolated amphibian gastric mucosa.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Animals; Bicarbonates; Ca | 1983 |
Comparative study of the cytoprotective effects of anticholinergic agents on the gastric mucosal lesions produced by intragastric administration of 0.6 M HCl in rats.
Topics: Animals; Female; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Male; Parasympatholytics; Rats; St | 1984 |
The interrelationships between the development of ethanol-, HCl, NaOH and NaCl-induced gastric mucosal damage and the gastric mucosal superoxide dismutase activity in the rats.
Topics: Animals; Ethanol; Female; Free Radicals; Gastric Mucosa; Hydrochloric Acid; Male; Rats; Sodium Chlor | 1984 |
Cytoprotective effect of SU-88, an anti-ulcer agent, in the rat.
Topics: Animals; Anti-Ulcer Agents; Cell Survival; Chalcone; Chalcones; Cimetidine; Dinoprostone; Ethanol; G | 1984 |
Effect of PGF2 alpha administered in cytoprotective and antisecretory doses on the ethanol- and HCl-induced gastric mucosal damage and gastric mucosal superoxide dismutase activity in rats.
Topics: Animals; Dinoprost; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Acid; Gastric Mucosa; | 1984 |
Acidification of arterial blood enhances gastric mucosal injury induced by bile salts in dogs.
Topics: Animals; Arteries; Carbon Dioxide; Dogs; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentrati | 1982 |
Effect of intraduodenal load of endogenous acid on secretin release in patients with peptic ulcer.
Topics: Adult; Duodenal Ulcer; Duodenum; Female; Gastric Acid; Gastrins; Humans; Hydrochloric Acid; Male; Mi | 1982 |
Effect of geranylgeranylacetone (GGA) on gastric lesions induced by topical aspirin plus HCl.
Topics: Administration, Topical; Animals; Aspirin; Diterpenes; Hydrochloric Acid; Male; Rats; Rats, Inbred S | 1982 |
Gastric stress ulcers and gastrointestinal hormones - response to hydrochloric acid and sodium chloride infused intraduodenally. Preliminary report.
Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Duodenum; Gastric Mucosa; Gastrointestinal | 1980 |
Prostaglandin E2 in gastric mucosa and its role in the prevention of ulcers induced by acetyl salicylic acid in cats.
Topics: Animals; Aspirin; Cats; Gastric Juice; Gastric Mucosa; Histamine; Hydrochloric Acid; Prostaglandins | 1981 |
[Prostaglandin E2 in the gastric mucosa. (3rd report) -Effect of mild acid- (author's transl)].
Topics: Animals; Gastric Mucosa; Hydrochloric Acid; Male; Prostaglandins E; Rats; Stomach Ulcer | 1981 |
Reduction of gastric stress ulcers by intraduodenal infusion of liquids--observations in a rat model.
Topics: Animals; Disease Models, Animal; Duodenum; Hydrochloric Acid; Infusions, Parenteral; Male; Rats; Res | 1980 |
Role of prostaglandins in the formation of aspirin-induced gastric ulcers.
Topics: Animals; Aspirin; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Male; Prostaglandin Antagonists; | 1981 |
Anti-ulcer effect of FK 506, immunosuppressive agent, in rats.
Topics: Animals; Anti-Ulcer Agents; Hydrochloric Acid; Immunosuppressive Agents; Male; Rats; Rats, Sprague-D | 1994 |
Effect of acute administration of fish oil (omega-3 marine triglyceride) on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Ethanol; Female; Fish Oils; Gastric Aci | 1995 |
The cytoprotective effect of the immunomodulator AS101 against hydrochloride induced gastric lesions.
Topics: Adjuvants, Immunologic; Animals; Dinoprostone; Dose-Response Relationship, Drug; Epidermal Growth Fa | 1995 |
Effect of a combination of ecabet sodium and cimetidine on experimentally induced gastric lesions and gastric mucosal resistance to ulcerogenic agents in rats.
Topics: Abietanes; Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Dinoprostone; Diterpenes; Drug Therapy, | 1995 |
Gastroprotective effect of aqueous extract of Cistus incanus L. in rats.
Topics: Animals; Ethanol; Flavonoids; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Medicine, Tradi | 1995 |
[A comparative study on anti-ulcer action of unprepared and calcined oyster shell].
Topics: Animals; Anti-Ulcer Agents; Ethanol; Female; Gastric Mucosa; Hydrochloric Acid; Male; Materia Medica | 1994 |
[Pharmacological studies on the effects of huanglian decoction on experimental gastric lesions in rats and antiemetic in pigeons].
Topics: Animals; Anti-Ulcer Agents; Antiemetics; Aspirin; Columbidae; Drug Combinations; Drugs, Chinese Herb | 1994 |
A novel antiulcerogenic stable radical prevents gastric mucosal lesions in rats.
Topics: Animals; Aspirin; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Gastric Mucosa; Hy | 1994 |
Effects of KW-5805, a new antiulcer agent, on experimental gastric and duodenal ulcers, gastric mucosal lesions by necrotizing agents and gastric acid secretion.
Topics: Animals; Anti-Ulcer Agents; Benzoxepins; Cimetidine; Depression, Chemical; Duodenal Ulcer; Ethanol; | 1994 |
Anti-ulcer effect of 1,6-dihydro-2-[2-(2-methylpropoxy) anilino]-6-oxo-5-pyrimidinecarboxylic acid on experimental gastric ulcers in rats.
Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Ethanol; Hydrochloric Acid; Male; p-Metho | 1994 |
Protection against necrotizing agents-induced gastric lesions in rats. Unrelated to inhibition of gastric motility.
Topics: Animals; Ethanol; Female; Gastrointestinal Motility; Hydrochloric Acid; Indomethacin; Male; Papaveri | 1994 |
Effects of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl] urea with potent gastric mucosal protective activity on acute gastric lesions and duodenal ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cyanides; Duodenal Ulcer; Epirizole; Ethanol; Gastric Mucosa; H | 1993 |
Role of polymorphonuclear leucocytes and oxygen-derived free radicals in the formation of gastric lesions induced by HCl/ethanol, and a possible mechanism of protection by anti-ulcer polysaccharide.
Topics: Allopurinol; Animals; Anti-Ulcer Agents; Carrageenan; Cattle; Cyclophosphamide; Ethanol; Free Radica | 1993 |
Effect of local acid-base status on gastric mucosal blood flow and surface cell injury by bile acid.
Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Blood; Blood Flow Velocity; Dogs; Epithelium; Gastric | 1994 |
Adaptive gastric mucosal cytoprotection in rats: different modes of action by three mild irritants.
Topics: Animals; Chemoreceptor Cells; Ethanol; Gastric Mucosa; Hydrochloric Acid; Irritants; Male; Rats; Rat | 1996 |
Effect of vitamin E and selenium on hypothermic restraint stress and chemically-induced ulcers.
Topics: Animals; Antioxidants; Cold Temperature; Hydrochloric Acid; Immobilization; Indomethacin; Rats; Rats | 1996 |
Mechanisms of acid injury in porcine gastroesophageal mucosa.
Topics: Acetates; Analysis of Variance; Animals; Electrophysiology; Esophageal Diseases; Esophagus; Fatty Ac | 1996 |
The importance of gastric emptying and mucosal folds in the adaptive cytoprotection of mild irritants in rats.
Topics: Adaptation, Physiological; Animals; Anti-Ulcer Agents; Ethanol; Gastric Emptying; Gastric Mucosa; Hy | 1995 |
The role of acid in the pathogenesis of indomethacin-induced gastric antral ulcers in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cimetidine; Female; Gastric Aci | 1996 |
[Effects of Cuban analog (SWR-104SA), a new histamine H2 receptor antagonist, on gastric acid secretion and experimental ulcer formation].
Topics: Animals; Dioxolanes; Ethanol; Gastric Acid; Gastrointestinal Motility; Guinea Pigs; Histamine H2 Ant | 1996 |
Role of nitric oxide in mucosal blood flow response and the healing of HCl-induced lesions in the rat stomach.
Topics: Animals; Blood Flow Velocity; Cell Membrane Permeability; Enzyme Inhibitors; Gastric Acid; Gastric M | 1997 |
Recovery of mucin content in surface layer of rat gastric mucosa after HCl-aspirin-induced mucosal damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Hydrochloric Acid; Hydrog | 1997 |
Bosentan, a novel synthetic mixed-type endothelin receptor antagonist, attenuates acute gastric mucosal lesions induced by indomethacin and HCl in the rat: role of endogenous endothelin-1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bosentan; Endothelin Receptor Antagonists; Endothe | 1997 |
Acid-induced gastric damage in rats is aggravated by starvation and prevented by several nutrients.
Topics: Amino Acids; Animals; Ascorbic Acid; Gastric Acid; Gastric Mucosa; Glucose; Glutathione; Hydrochlori | 1997 |
The indomethacin-induced gastric mucosal damage in rats. Effect of gastric acid, acid inhibition, capsaicin-type agents and prostacyclin.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diterpenes; E | 1997 |
Studies on the antisecretory, gastric anti-ulcer and cytoprotective properties of glycine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Caustics; Disease Models, Anima | 1997 |
Effect of evening primrose oil on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dietary Fats, Unsaturated; E | 1997 |
Anti-ulcer effects of antioxidants: effect of probucol.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; D | 1998 |
Anti-ulcer effects of antioxidants, quercetin, alpha-tocopherol, nifedipine and tetracycline in rats.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Antioxidants; Calcium Channel Blocke | 1998 |
Protection by Rhinax in various models of ulceration in rats.
Topics: Animals; Gastric Acid; Gastric Mucins; Hydrochloric Acid; Indomethacin; Ligation; Male; Medicine, Ay | 1998 |
A novel method to produce extensive gastric antral ulcer in rats: pharmacological factors involved in the etiology of antral ulceration.
Topics: Animals; Dimethyl Sulfoxide; Ditiocarb; Gastric Mucosa; Glutathione; Humans; Hydrochloric Acid; Male | 1999 |
Importance of histamine, glutathione and oxyradicals in modulating gastric haemorrhagic ulcer in septic rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Dose-Response Relationship, Drug; Free Radical Scavenger | 2000 |
Isolation of the antiulcer compound in essential oil from the leaves of Cryptomeria japonica.
Topics: Acetaldehyde; Animals; Anti-Ulcer Agents; Aspirin; Cycadopsida; Disease Models, Animal; Gastric Juic | 2000 |
Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase 1; Cycl | 2000 |
Nitric oxide donating compounds inhibit HCl-induced gastric mucosal lesions mainly via prostaglandin.
Topics: 16,16-Dimethylprostaglandin E2; Administration, Oral; Animals; Gastric Mucosa; Hydrochloric Acid; In | 2001 |
Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat.
Topics: Animals; beta-Endorphin; Brain; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; | 2001 |
Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout mice.
Topics: Adaptation, Physiological; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; C | 2001 |
Acid regulates inflammatory response in a rat model of induction of gastric ulcer recurrence by interleukin 1beta.
Topics: Analysis of Variance; Animals; Anti-Ulcer Agents; Enzyme-Linked Immunosorbent Assay; Gastric Acid; H | 2001 |
Low gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in rats with cirrhosis and arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Blood Flow Veloc | 2001 |
Effects of diacerein on indomethacin-induced gastric ulceration.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Dinoprostone; D | 2001 |
Role of histamine in aggravation of gastric acid back-diffusion and vascular permeability in septic rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Bacterial Infections; Capillary Permeability; Diffusion; | 2001 |
Gastroprotective activity of oleanolic acid derivatives on experimentally induced gastric lesions in rats and mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Dose-Response Relation | 2002 |
Agonists for the histamine H3-receptor differ in their gastroprotective activity in the rat.
Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Histamine Agonists; Hydrochloric Acid; Imidazoles; Imine | 2002 |
Gastroprotective activity of the diterpene solidagenone and its derivatives on experimentally induced gastric lesions in mice.
Topics: Animals; Anti-Ulcer Agents; Biotransformation; Disease Models, Animal; Diterpenes; Ethanol; Furans; | 2002 |
Ulcer formation and histochemical changes in rat-stomach mucosa induced by acetylsalicylic acid.
Topics: Adenosine Triphosphatases; Animals; Aspirin; Dihydrolipoamide Dehydrogenase; Duodenum; Electron Tran | 1976 |
Effect of pH on bile salt injury to mouse gastric mucosa. A light- and electron-microscopic study.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Dose-Response Relationship, Drug; Gastric Muco | 1975 |
Failure of cholestyramine to prevent bile salt injury to mouse gastric mucosa.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestyramine Resin; Disease Models, Animal; | 1975 |
Topical aspirin plus HCl gastric lesions in the rat. Cytoprotective effect of prostaglandin, cimetidine, and probanthine.
Topics: Animals; Aspirin; Cimetidine; Depression, Chemical; Gastric Juice; Guanidines; Hydrochloric Acid; In | 1979 |
Protection by trimipramine against gastric mucosal barrier dysfunction induced by ethanol + HC1 in rats.
Topics: Animals; Dibenzazepines; Drug Evaluation, Preclinical; Ethanol; Female; Gastric Mucosa; Hydrochloric | 1979 |
The gastric mucosal microcirculation during erosion formation in the rat.
Topics: Animals; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Microcirculation; Rats; Regional Blood Flo | 1977 |
Histamine augments gastric ulceration produced by intravenous aspirin in cats.
Topics: Animals; Aspirin; Cats; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Female; | 1978 |
Cimetidine and prostaglandin prevent damage to gastric mucosa.
Topics: Animals; Aspirin; Cimetidine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gastri | 1978 |
Distention ulcer as a model for testing of drugs for ulcerogenic side effects.
Topics: Animals; Aspirin; Disease Models, Animal; Hydrochloric Acid; Indomethacin; Male; Rats; Stomach; Stom | 1978 |
Effect of histamine H2 antagonism by metiamide on the response of the canine gastric mucosa to acid and bile salt.
Topics: Animals; Cell Membrane Permeability; Dogs; Gastric Acidity Determination; Gastric Mucosa; Hydrochlor | 1977 |
Mucosal lesions due to gastric distension in the rat.
Topics: Animals; Gastric Mucosa; Hydrochloric Acid; Male; Pressure; Rats; Stomach; Stomach Ulcer | 1977 |
Stimulation of human pepsin output by tropical hydrochloric acid.
Topics: Adolescent; Adult; Dextrans; Diffusion; Female; Gastric Juice; Gastric Mucosa; Humans; Hydrochloric | 1975 |
Reversibility of pyloric sphincter dysfunction in gastric ulcer.
Topics: Adult; Amino Acids; Female; Gastric Juice; Gastrins; Humans; Hydrochloric Acid; Male; Middle Aged; O | 1975 |
Manometric studies on the human pyloric sphincter. Effect of cigarette smoking, metoclopramide, and atropine.
Topics: Adult; Atropine; Gastrointestinal Motility; Humans; Hydrochloric Acid; Intubation, Gastrointestinal; | 1976 |
Effect of sialoadenectomy on stomach lesions induced by indomethacin and ethanol in relation to gastric vascular permeability, the gastrin level and HCl secretion in rats.
Topics: Animals; Capillary Permeability; Epidermal Growth Factor; Ethanol; Gastrins; Hydrochloric Acid; Indo | 1992 |
Effect of DS-4574, a novel peptidoleukotriene antagonist with mast cell stabilizing action, on acute gastric lesions and gastric secretion in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Gastric | 1992 |
Effects of histamine H2-receptor antagonists and a proton pump inhibitor on the mucosal hydroxyproline content of ethanol-HCl-induced gastric lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benz | 1992 |
Effect of aspirin on ulcer site blood flow in cat stomachs.
Topics: Animals; Aspirin; Cats; Dose-Response Relationship, Drug; Female; Hydrochloric Acid; Regional Blood | 1992 |
A reliable method for the production of antral gastric ulcer by a combination of 2-deoxy-D-glucose, aspirin and ammonia in rats.
Topics: Administration, Oral; Ammonia; Animals; Aspirin; Deoxyglucose; Disease Models, Animal; Drug Interact | 1991 |
Role of oxygen-derived free radicals in indomethacin-induced gastric injury.
Topics: Allopurinol; Animals; Catalase; Chromium Radioisotopes; Deferoxamine; Free Radical Scavengers; Free | 1991 |
[Evaluation of HCl-induced gastric mucosal lesions using a computer image processing system].
Topics: Animals; Gastric Mucosa; Hydrochloric Acid; Image Processing, Computer-Assisted; Male; Necrosis; Rat | 1991 |
Protection by copper (II) complexes in various models of ulceration in rat.
Topics: Animals; Anti-Ulcer Agents; Copper; Gastric Acid; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, | 1991 |
[Imaging analysis of antiulcer action and the active constituent of Atractylodis rhizoma].
Topics: Animals; Anti-Ulcer Agents; Drugs, Chinese Herbal; Electronic Data Processing; Ethanol; Hydrochloric | 1991 |
Effects of a crude extract of a marine dinoflagellate, containing dimethyl-beta-propiothetin, on HCl.ethanol-induced gastric lesions and gastric secretion in rats.
Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Ethanol; Eukaryota; Gastric Mucosa; Hy | 1990 |
Role of active oxygen species in diethyldithiocarbamate-induced gastric ulcer in the rat.
Topics: Animals; Catalase; Ditiocarb; Free Radicals; Hydrochloric Acid; Hydrogen Peroxide; Oxygen; Pyloric A | 1990 |
Effect of endothelium-derived relaxing factor on the gastric lesion induced by HCl in rats.
Topics: Acetylcholine; Animals; Drug Interactions; Electric Stimulation; Gastric Mucosa; Hemodynamics; Hydro | 1990 |
Intraluminal release of PGE2 due to gastric perfusion of urethane-anaesthetized rats with hydrochloric or taurocholic acid.
Topics: Anesthesia; Animals; Dinoprostone; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Im | 1990 |
Effects of liver extract from the ocean sunfish (Mola mola) on acute gastric lesions in the rat.
Topics: Animals; Cimetidine; Hydrochloric Acid; Indomethacin; Liver Extracts; Male; Perciformes; Rats; Rats, | 1990 |
Gastric protective activity of mixtures of saturated polar and neutral lipids in rats.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Aspirin; Bile Acids and Salts; Drug Combinations; Ethan | 1990 |
Biochemical background of beta-carotene-induced gastric cytoprotection in rats treated with HCl.
Topics: Animals; Anti-Ulcer Agents; beta Carotene; Carotenoids; Gastric Mucosa; Hydrochloric Acid; Male; Rat | 1990 |
Similarities and differences in the cytoprotection induced by PGI2 and beta-carotene in experimental ulcer.
Topics: Animals; beta Carotene; Carotenoids; Epoprostenol; Ethanol; Female; Gastric Mucosa; Hydrochloric Aci | 1989 |
Does acidosis contribute to stress-induced ulceration in rat stomachs?
Topics: Acidosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Cold Temperature; Female; Hydrochloric | 1989 |
Gastroprotective activity of ginger zingiber officinale rosc., in albino rats.
Topics: Animals; Aspirin; Drugs, Chinese Herbal; Ethanol; Female; Hydrochloric Acid; Indomethacin; Male; Rat | 1989 |
Effect of cytoprotective and antiulcer drugs on the healing process of subacute gastric ulcer in rat (a new model).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Disease Models, Animal; Ethylma | 1989 |
The free radical mechanisms in beta-carotene induced gastric cytoprotection in HCl model.
Topics: Animals; beta Carotene; Carotenoids; Catalase; Disease Models, Animal; Female; Free Radicals; Gastri | 1989 |
Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach.
Topics: Animals; Blood Pressure; Diterpenes; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vas | 1989 |
Luminal acid in stress ulceration and the antiulcer action of verapamil in rat stomachs.
Topics: Animals; Anti-Ulcer Agents; Bethanechol Compounds; Female; Gastric Acid; Hydrochloric Acid; In Vitro | 1986 |
Comparison of the ulcerogenicity of indomethacin and the gastric secretion in verapamil-treated rats.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Hydroge | 1988 |
Vascular injury in acute gastric mucosal damage. Mediatory role of leukotrienes.
Topics: Animals; Capillary Permeability; Ethanol; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Hydro | 1988 |
Suppression of gastric ulcer induced by stress and HCL-ethanol by intravenously administered metallothionein-II.
Topics: Acetates; Acetic Acid; Animals; Cimetidine; Ethanol; Hydrochloric Acid; Male; Metallothionein; Rats; | 1988 |
Protection by opioids against gastric lesions caused by necrotizing agents.
Topics: Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Gastric Mucosa; Hydrochloric Acid; Male | 1988 |
[Effects of endogenous epidermal growth factor (EGF) on acid secretion, intramucosal mucus and HC1-induced mucosal injury in the stomach in submandibular gland removed rats].
Topics: Animals; Epidermal Growth Factor; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Hydro | 1987 |
Role of endogenous gastric mucosal prostaglandins in the formation of acute gastric mucosal lesions induced by aspirin, ethanol, HCl and CH3COOH.
Topics: Acetates; Acute Disease; Administration, Oral; Animals; Aspirin; Ethanol; Gastric Mucosa; Hydrochlor | 1987 |
[Protective effect of dicloguamine maleate (MN-1695) on HCl-induced gastric mucosal damage in rats--histologic studies].
Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Hydrochloric Acid; Male; Rats; Rats, Inbred Strains; Sto | 1987 |
Effects of NC-1300 and its degradation products on gastric secretion and HCl.ethanol-induced gastric lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Benzimidazoles; Drug Stability; Ethanol; Gastric A | 1987 |
Development of gastric mucosal protection against acid in the rat. Role of corticosteroids and prostaglandins.
Topics: Age Factors; Animals; Animals, Suckling; Cell Differentiation; Dinoprostone; Gastric Mucosa; Hydroch | 1986 |
Cytoprotective effects of NC-1300 and omeprazole on Hcl . ethanol-induced gastric lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Ethanol; Ethylm | 1986 |
Gastric cytoprotection by pirenzepine in rats: evaluating method for cytoprotective activity by antisecretory agents.
Topics: Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Buffers; Cimetidine; Dinoprostone; Ethanol; | 1985 |
[Effects of 2-benzyloxycarbonylphenyl trans-4-guanidinomethylcyclohexanecarboxylate hydrochloride monohydrate (TKG01) and its clathrate compound with beta-cyclodextrin (TA903) on experimental gastric ulcers and gastric secretion in rats].
Topics: Animals; Anti-Ulcer Agents; beta-Cyclodextrins; Cyclodextrins; Cyclohexanecarboxylic Acids; Dextrins | 1985 |
[Studies on pathophysiology of peptic ulcer. Neutralization by pancreatic juice secretion into the duodenal lumen after HCL loading].
Topics: Adult; Aged; Bicarbonates; Duodenal Ulcer; Female; Gastric Acidity Determination; Gastric Juice; Hum | 1985 |
Gastric antral ulcers induced by a combination of acid, indomethacin and ischemia in rats.
Topics: Animals; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Ischemia; Male; Pyloric Antrum; Rats; Rats | 1985 |
Letter: Pain in gastric ulcer.
Topics: Hydrochloric Acid; Pain; Stomach; Stomach Ulcer | 1974 |
Letter: Pain in gastric ulcer.
Topics: Esophagus; Humans; Hydrochloric Acid; Neurons; Pain; Reflex; Stomach Ulcer | 1974 |
Histochemical evidence for the role of macromolecular structural stability in the pathogenesis of diseases.
Topics: Adult; Aged; Aorta; Arteriosclerosis; Arthritis, Rheumatoid; Collagen; Connective Tissue; Ear Ossicl | 1970 |
[Esophageal symptoms and their relationships to the result of the perfusion test and to the histological mucosal finding in the esophagus].
Topics: Biopsy; Duodenal Ulcer; Esophagitis; Esophagus; Heartburn; Hernia, Diaphragmatic; Humans; Hydrochlor | 1974 |
Pyloric channel ulcer with betazole-fast achlorhydria.
Topics: Achlorhydria; Aged; Biopsy; Gastrectomy; Gastric Acidity Determination; Gastric Juice; Gastric Mucos | 1974 |
Response to duodenal acidification in man. IV. Effct on gastric emptying.
Topics: Acid-Base Equilibrium; Cobalt Isotopes; Duodenal Ulcer; Duodenum; Gastric Mucosa; Gastrointestinal M | 1972 |
Pyloric-sphincter dysfunction in patients with gastric ulcer.
Topics: Aged; Amino Acids; Cholecystokinin; Duodenum; Female; Fluoroscopy; Gastric Juice; Gastrointestinal M | 1973 |
Failure of ischemia to break the dog's gastric mucosal barrier.
Topics: Aminopyrine; Animals; Bethanechol Compounds; Blood Pressure; Diffusion; Dogs; Gastric Mucosa; Hemorr | 1973 |
Pepsin output from the damaged canine Heidenhain pouch.
Topics: Animals; Dogs; Gastric Mucosa; Hydrochloric Acid; Methods; Pepsin A; Stomach Ulcer | 1971 |
Adenosine deaminase in gastric juice.
Topics: Adenosine; Adolescent; Adult; Aminohydrolases; Carcinoma; Duodenal Ulcer; Gastric Juice; Gastritis; | 1972 |
Radio-immunoassay of gastrin in human plasma.
Topics: Achlorhydria; Anemia, Pernicious; Animals; Atropine; Dietary Proteins; Duodenal Ulcer; Gastrins; Gui | 1972 |
The role of vagotomy in preventing bile salt-induced stress ulcers during hemorrhagic shock.
Topics: Animals; Bile Acids and Salts; Disease Models, Animal; Dogs; Gastric Mucosa; Hydrochloric Acid; Hydr | 1972 |
[Physiology of the gastric antrum].
Topics: Gastrins; Humans; Hydrochloric Acid; Stomach; Stomach Ulcer | 1968 |
Response to duodenal acidification in man. I. Electrolyte changes in the duodenal aspirate.
Topics: Achlorhydria; Chlorides; Duodenal Ulcer; Duodenum; Gastric Juice; Humans; Hydrochloric Acid; Inhalat | 1969 |
Proteins and sialic acid in the gastric juice of humans.
Topics: Biliary Tract Diseases; Duodenal Ulcer; Gastric Acidity Determination; Gastric Juice; Gastritis; Gly | 1968 |
Response of the normal and pathological human gastric mucosa to an instilled acid load.
Topics: Absorption; Anemia, Pernicious; Biological Transport; Electrolytes; Gastric Acidity Determination; G | 1968 |