hydrochloric acid has been researched along with Pneumonia, Aspiration in 96 studies
Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
Pneumonia, Aspiration: A type of lung inflammation resulting from the aspiration of food, liquid, or gastric contents into the upper RESPIRATORY TRACT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuronal activity in the medulla oblongata and neurogenic inflammation of airways were investigated in a guinea pig model induced by repeated intra-esophageal instillation of hydrochloric acid (HCl) after vagotomy." | 3.85 | Vagotomy decreases the neuronal activities of medulla oblongata and alleviates neurogenic inflammation of airways induced by repeated intra-esophageal instillation of HCl in guinea pigs. ( Chen, F; Chen, H; Chen, Z; Dong, R; Fan, L; Gu, D; Lai, K; Lin, Y; Sun, L; Zhang, W, 2017) |
| "Aspiration of hydrochloric acid (HCl)-containing gastric juice leads to acute lung injury (ALI) and hypoxemic respiratory failure due to an exuberant inflammatory response associated with pulmonary edema from increased vascular and epithelial permeability." | 3.78 | Acid-induced acute lung injury in mice is associated with P44/42 and c-Jun N-terminal kinase activation and requires the function of tumor necrosis factor α receptor I. ( Armaganidis, A; Kollias, G; Kotanidou, A; Magkou, C; Maniatis, NA; Nikitopoulou, I; Orfanos, SE; Roussos, C; Sfika, A; Vassiliou, AG, 2012) |
| "Recent investigations of the role of large infusions of concentrated serum albumin on the acute pulmonary edema caused by hydrochloric acid (HCl) aspiration have produced contradictory results." | 3.66 | Concentrated albumin does not affect lung edema formation after acid instillation in the dog. ( Bhattacharya, J; Nanjo, S; Staub, NC, 1983) |
| "Hydrochloric acid was added to the control feeding to titrate the pH to 3." | 2.67 | Effect of acidified enteral feedings on gastric colonization in the critically ill patient. ( Bradley, C; Heyland, D; Mandell, LA, 1992) |
| "Acid instillation caused pulmonary edema, measured as increased extravascular lung water index (ELWI), impaired gas exchange and increased mean pulmonary artery pressure." | 1.38 | Effects of pulmonary acid aspiration on the lungs and extra-pulmonary organs: a randomized study in pigs. ( Beißbarth, T; Bleckmann, A; Brück, W; Crozier, TA; Herrmann, P; Heuer, JF; Pelosi, P; Perske, C; Quintel, M; Sauter, P; Schöndube, F, 2012) |
| "Lung injury was induced by instillation of 0." | 1.35 | The effects of fenoterol inhalation after acid aspiration-induced lung injury. ( Gruber, M; Hopf, S; Ittner, KP; Lubnow, M; Pawlik, MT; Schubert, T; Selig, C; Taeger, K, 2009) |
| "In pentoxifylline-treated rats, Pao(2) was significantly increased (p < 0." | 1.33 | Early treatment with pentoxifylline reduces lung injury induced by acid aspiration in rats. ( Feuerbach, S; Gruber, M; Ittner, KP; Pawlik, MT; Schreyer, AG; Selig, C; Taeger, K, 2005) |
| "Rats given CASP had the most severe lung injury at 6, 24, and 48 h based on decreases in arterial oxygenation and increases in erythrocytes, total leukocytes, neutrophils, total protein, and albumin in bronchoalveolar lavage (BAL)." | 1.33 | Surfactant alterations in acute inflammatory lung injury from aspiration of acid and gastric particulates. ( Chess, PR; Davidson, BA; Holm, BA; Hutson, A; Knight, PR; Notter, RH; Russo, TA; Wang, Z, 2005) |
| "Aspiration pneumonia was found to significantly increase the mortality rate in acid injured patients who required emergency abdominal surgery (87." | 1.31 | Outcome of acid ingestion related aspiration pneumonia. ( Lai, WW; Lin, MY; Tseng, YL; Wu, MH, 2002) |
| "The results show that at the site of aspiration pneumonia, anti-CD11b F(ab')2 did not inhibit neutrophil sequestration or edema formation, either with or without endotoxin pretreatment." | 1.30 | Role of CD11b in focal acid-induced pneumonia and contralateral lung injury in rats. ( Bree, M; Doerschuk, CM; Motosugi, H; Quinlan, WM, 1998) |
| "Lidocaine pretreatment attenuated these changes." | 1.30 | Intravenous lidocaine attenuates acute lung injury induced by hydrochloric acid aspiration in rabbits. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M; Takao, Y, 1998) |
| "Acute tracheal injury model (Mendelson Syndrome) were made." | 1.29 | [An aspiration pneumonia in acute airway damage model induced by HCl and/or LPS]. ( Fukuchi, Y; Higashimoto, Y; Ishida, K; Jo, C; Matsui, H; Matsuse, T; Nagase, T; Oka, T; Sudo, E; Teramoto, S, 1993) |
| "Respiratory failure was induced by intratracheal instillation of HCl (0." | 1.29 | Surfactant treatment of respiratory failure induced by hydrochloric acid aspiration in rats. ( Eijking, EP; Gommers, D; Lachmann, B; So, KL; Vergeer, M, 1993) |
| "Experimental aspiration pneumonia induced in the isolated perfused ventilated canine pulmonary lobe by the intrabronchial instillation of hydrochloric acid is characterized by pulmonary edema, intrapulmonary shunting, and loss of lung compliance." | 1.27 | Aspiration pneumonia: treatment with pulmonary vasodilators. ( Broe, PJ; Cameron, JL; Permutt, S; Toung, TJ, 1983) |
| "Cell necrosis was followed by loss of surfactant and formation of hyaline membranes, rich in immunoglobulin M." | 1.27 | The gastric juice aspiration syndrome (Mendelson syndrome). Aspects of pathogenesis and treatment in the pig. ( Juettner, F; Pinter, J; Popper, H, 1986) |
| "The aspiration of gastric acid causes pulmonary edema and hypoxemia." | 1.27 | Treatment of canine aspiration pneumonitis: fluid volume reduction vs. fluid volume expansion. ( Breen, PH; Long, R; Mayers, I; Wood, LD, 1988) |
| "Hydrochloric acid was instilled into the bronchial tree in anaesthetized dogs." | 1.25 | Ventilation and blood-gas studies during experimentally produced Mendelson's syndrome in the dog. ( Fabre, J; Francois, G; Gouin, F; Ohresser, P; Tournigand, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (51.04) | 18.7374 |
| 1990's | 18 (18.75) | 18.2507 |
| 2000's | 22 (22.92) | 29.6817 |
| 2010's | 6 (6.25) | 24.3611 |
| 2020's | 1 (1.04) | 2.80 |
| Authors | Studies |
|---|---|
| Puri, G | 1 |
| Naura, AS | 1 |
| Chen, Z | 1 |
| Chen, H | 1 |
| Chen, F | 1 |
| Gu, D | 1 |
| Sun, L | 1 |
| Zhang, W | 1 |
| Fan, L | 1 |
| Lin, Y | 1 |
| Dong, R | 1 |
| Lai, K | 1 |
| Zhang, Y | 1 |
| Zhao, Z | 1 |
| Guan, L | 1 |
| Mao, L | 1 |
| Li, S | 1 |
| Guan, X | 1 |
| Chen, M | 1 |
| Guo, L | 1 |
| Ding, L | 1 |
| Cong, C | 1 |
| Wen, T | 1 |
| Zhao, J | 1 |
| Pawlik, MT | 3 |
| Lubnow, M | 3 |
| Gruber, M | 4 |
| Taeger, K | 3 |
| Riegger, G | 1 |
| Pfeifer, M | 1 |
| Ittner, KP | 4 |
| Trabold, B | 1 |
| Pawlik, M | 1 |
| Nietsch, R | 1 |
| Bitzinger, DI | 1 |
| Schubert, T | 1 |
| Hopf, S | 1 |
| Selig, C | 2 |
| Jian, MY | 4 |
| Koizumi, T | 4 |
| Tsushima, K | 3 |
| Yokoyama, T | 2 |
| Kubo, K | 4 |
| Baba, A | 1 |
| Heuer, JF | 1 |
| Sauter, P | 1 |
| Pelosi, P | 1 |
| Herrmann, P | 1 |
| Brück, W | 1 |
| Perske, C | 1 |
| Schöndube, F | 1 |
| Crozier, TA | 1 |
| Bleckmann, A | 1 |
| Beißbarth, T | 1 |
| Quintel, M | 1 |
| Westphalen, K | 1 |
| Monma, E | 1 |
| Islam, MN | 1 |
| Bhattacharya, J | 3 |
| Maniatis, NA | 1 |
| Sfika, A | 1 |
| Nikitopoulou, I | 1 |
| Vassiliou, AG | 1 |
| Magkou, C | 1 |
| Armaganidis, A | 1 |
| Roussos, C | 1 |
| Kollias, G | 1 |
| Orfanos, SE | 1 |
| Kotanidou, A | 1 |
| Mitsushima, H | 1 |
| Oishi, K | 1 |
| Nagao, T | 1 |
| Ichinose, A | 1 |
| Senba, M | 1 |
| Iwasaki, T | 1 |
| Nagatake, T | 1 |
| Rubin, AE | 1 |
| Wang, KP | 1 |
| Liu, MC | 1 |
| GIANI, E | 1 |
| MORAN, TJ | 1 |
| Hagio, T | 1 |
| Matsumoto, S | 1 |
| Nakao, S | 1 |
| Abiru, T | 1 |
| Ohno, H | 1 |
| Kawabata, K | 1 |
| Schreyer, AG | 1 |
| Feuerbach, S | 1 |
| Davidson, BA | 3 |
| Knight, PR | 3 |
| Wang, Z | 1 |
| Chess, PR | 1 |
| Holm, BA | 3 |
| Russo, TA | 2 |
| Hutson, A | 1 |
| Notter, RH | 3 |
| Fujimoto, K | 2 |
| Raghavendran, K | 1 |
| Mullan, BA | 1 |
| Hutson, AD | 1 |
| Manderscheid, PA | 1 |
| Woytash, JA | 1 |
| Zhao, SP | 1 |
| Guo, QL | 1 |
| Ai, YH | 1 |
| Wang, RK | 1 |
| Wang, E | 1 |
| He, M | 1 |
| Safdar, Z | 1 |
| Yiming, M | 1 |
| Grunig, G | 1 |
| Allen, GB | 1 |
| Leclair, T | 1 |
| Cloutier, M | 1 |
| Thompson-Figueroa, J | 1 |
| Bates, JH | 1 |
| Amigoni, M | 1 |
| Bellani, G | 1 |
| Scanziani, M | 1 |
| Masson, S | 1 |
| Bertoli, E | 1 |
| Radaelli, E | 1 |
| Patroniti, N | 1 |
| Di Lelio, A | 1 |
| Pesenti, A | 1 |
| Latini, R | 1 |
| East, TD | 2 |
| Pace, NL | 2 |
| Westenskow, DR | 2 |
| Lund, K | 1 |
| Buchman, SR | 1 |
| Sugerman, HJ | 1 |
| Tatum, JL | 1 |
| Wright, TP | 1 |
| Blocher, CR | 1 |
| Hirsch, JI | 1 |
| Tuchman, DN | 1 |
| Boyle, JT | 1 |
| Pack, AI | 1 |
| Scwartz, J | 1 |
| Kokonos, M | 1 |
| Spitzer, AR | 1 |
| Cohen, S | 1 |
| Akama, Y | 1 |
| Nanjo, S | 1 |
| Staub, NC | 1 |
| James, CF | 1 |
| Modell, JH | 3 |
| Gibbs, CP | 3 |
| Kuck, EJ | 3 |
| Ruiz, BC | 1 |
| Broe, PJ | 1 |
| Toung, TJ | 2 |
| Permutt, S | 1 |
| Cameron, JL | 4 |
| Nakatani, J | 2 |
| Beppu, OS | 1 |
| Gianotti Filho, O | 1 |
| dos Santos, ML | 2 |
| Ratto, OR | 1 |
| Peitzman, AB | 1 |
| Shires, GT | 2 |
| Illner, H | 1 |
| Lowrey, LD | 1 |
| Anderson, M | 1 |
| Calhoun, J | 1 |
| Edmonds, H | 1 |
| Flint, LM | 1 |
| Wynne, JW | 4 |
| Romaldini, H | 1 |
| Jardim, JR | 1 |
| Bogossian, M | 1 |
| Ramphal, R | 1 |
| Hood, CI | 4 |
| Schwartz, DJ | 2 |
| Rabinovici, R | 2 |
| Neville, LF | 2 |
| Abdullah, F | 1 |
| Phillip, DR | 1 |
| Vernick, J | 2 |
| Fong, KL | 1 |
| Hillegas, L | 2 |
| Feuerstein, G | 1 |
| Aoyagi, M | 1 |
| Sudo, E | 2 |
| Fukuchi, Y | 2 |
| Ishida, K | 2 |
| Matsuse, T | 2 |
| Nagase, T | 2 |
| Teramoto, S | 2 |
| Jo, C | 2 |
| Matsui, H | 2 |
| Higashimoto, Y | 2 |
| Oka, T | 2 |
| Rosenfeld, BA | 1 |
| Yoshiki, A | 1 |
| Grayson, RF | 1 |
| Traystman, RJ | 1 |
| Goldman, G | 2 |
| Welbourn, R | 2 |
| Klausner, JM | 1 |
| Kobzik, L | 4 |
| Valeri, CR | 3 |
| Shepro, D | 3 |
| Hechtman, HB | 4 |
| Eijking, EP | 1 |
| Gommers, D | 1 |
| So, KL | 1 |
| Vergeer, M | 1 |
| Lachmann, B | 1 |
| Schertel, ER | 1 |
| Pratt, JW | 1 |
| Schaefer, SL | 1 |
| Valentine, AK | 1 |
| McCreary, MR | 1 |
| Myerowitz, PD | 1 |
| Motosugi, H | 1 |
| Quinlan, WM | 1 |
| Bree, M | 1 |
| Doerschuk, CM | 1 |
| Nishina, K | 1 |
| Mikawa, K | 1 |
| Takao, Y | 1 |
| Shiga, M | 1 |
| Maekawa, N | 1 |
| Obara, H | 1 |
| Modelska, K | 1 |
| Pittet, JF | 1 |
| Folkesson, HG | 1 |
| Courtney Broaddus, V | 1 |
| Matthay, MA | 1 |
| Kawamae, K | 1 |
| Pristine, G | 1 |
| Chiumello, D | 1 |
| Tremblay, LN | 1 |
| Slutsky, AS | 1 |
| Kurek, C | 1 |
| Nader, ND | 1 |
| Patel, A | 1 |
| Sokolowski, J | 1 |
| Kudoh, I | 1 |
| Miyazaki, H | 1 |
| Yamada, H | 1 |
| Fujimoto, J | 1 |
| Ohara, M | 1 |
| Tazawa, T | 1 |
| Fukushima, J | 1 |
| Okumura, F | 1 |
| Ishizuka, S | 1 |
| Yamaya, M | 1 |
| Suzuki, T | 1 |
| Nakayama, K | 1 |
| Kamanaka, M | 1 |
| Ida, S | 1 |
| Sekizawa, K | 1 |
| Sasaki, H | 1 |
| Kyriakides, C | 1 |
| Wang, Y | 1 |
| Austen, WG | 1 |
| Favuzza, J | 1 |
| Moore, FD | 1 |
| Tseng, YL | 1 |
| Wu, MH | 1 |
| Lin, MY | 1 |
| Lai, WW | 1 |
| Henderson, RD | 1 |
| Fung, K | 1 |
| Cullen, JB | 1 |
| Milne, EN | 1 |
| Marryatt, G | 1 |
| Fabre, J | 1 |
| Ohresser, P | 1 |
| Gouin, F | 1 |
| Tournigand, T | 1 |
| Francois, G | 1 |
| Kudsk, KA | 1 |
| Pflug, B | 1 |
| Lowery, BD | 1 |
| Jones, JG | 1 |
| Grossman, RF | 1 |
| Berry, M | 1 |
| Slavin, G | 1 |
| Hulands, GH | 1 |
| Minty, B | 1 |
| Hodd, CI | 1 |
| Morino, U | 1 |
| Radeschi, G | 1 |
| Gorerino, F | 1 |
| Fiandino, G | 1 |
| Salley, S | 1 |
| Santo, GD | 1 |
| Barnhart, MI | 1 |
| Winsel, K | 1 |
| Kuckelt, W | 1 |
| Dauberschmidt, R | 1 |
| Iwainsky, H | 1 |
| Geer, RT | 1 |
| Soma, LR | 2 |
| Barnes, C | 1 |
| Leatherman, JL | 1 |
| Marshall, BE | 3 |
| Dodd, DC | 1 |
| Leatherman, J | 1 |
| Heyland, D | 1 |
| Bradley, C | 1 |
| Mandell, LA | 1 |
| Veddeng, OJ | 1 |
| Myhre, ES | 1 |
| Risøe, C | 1 |
| Smiseth, OA | 1 |
| Kobayashi, T | 1 |
| Ganzuka, M | 1 |
| Taniguchi, J | 1 |
| Nitta, K | 1 |
| Murakami, S | 1 |
| Stothert, JC | 2 |
| Gbaanador, GB | 1 |
| Basadre, J | 1 |
| Flynn, J | 1 |
| Traber, L | 2 |
| Traber, D | 2 |
| Ishii, Y | 1 |
| Kobayashi, J | 1 |
| Kitamura, S | 1 |
| Basadre, JO | 1 |
| Herndon, D | 1 |
| Popper, H | 1 |
| Juettner, F | 1 |
| Pinter, J | 1 |
| Ducolone, A | 1 |
| Vandevenne, A | 1 |
| Jouin, H | 1 |
| Grob, JC | 1 |
| Coumaros, D | 1 |
| Meyer, C | 1 |
| Burghard, G | 1 |
| Methlin, G | 1 |
| Hollender, L | 1 |
| Long, R | 1 |
| Breen, PH | 1 |
| Mayers, I | 1 |
| Wood, LD | 1 |
| Griffeth, JK | 1 |
| Gallagher, TJ | 1 |
| Packer, DL | 1 |
| Manny, J | 1 |
| Manny, N | 1 |
| Lelcuk, S | 1 |
| Alexander, F | 1 |
| Feingold, H | 1 |
| Taylor, G | 1 |
| Pryse-Davies, J | 1 |
| Booth, DJ | 1 |
| Zuidema, GD | 3 |
| Caldini, P | 1 |
| Toung, JK | 1 |
| Vilinskas, J | 1 |
| Schweizer, RT | 1 |
| Foster, JH | 1 |
| Chapman, RL | 2 |
| Downs, JB | 2 |
| Vaage, J | 1 |
| Hauge, A | 1 |
| Akcay, F | 1 |
| Ackerman, NB | 1 |
| Dudley, WR | 1 |
| Rafulia, VA | 1 |
| Blagodarov, VN | 1 |
| Rubin, S | 1 |
| Davidson, JT | 1 |
| Eyal, Z | 1 |
| Sebor, J | 1 |
| Anderson, RP | 1 |
| Pamintuan, RL | 1 |
| Brashear, RE | 1 |
| Ross, JC | 1 |
| DeAtley, RE | 1 |
| Gorman, JF | 1 |
| Glow, DE | 1 |
| Rejent, M | 1 |
| Stansell, G | 1 |
| Rosenberg, JC | 1 |
| Greenfield, LJ | 1 |
| Singleton, RP | 1 |
| McCaffree, DR | 1 |
| Coalson, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Continuous Versus Intermittent Bolus Feeding in Very Preterm Infants - Effects on Respiratory Morbidity: A Multicentre Randomised Controlled Clinical Trial[NCT03961139] | 150 participants (Anticipated) | Interventional | 2019-12-03 | Recruiting | |||
| A Randomised Controlled Trial Examining the Effect of Premedicant Oral Paracetamol on Gastric Residual Volume and pH in Children, in the Context of a 1-hour Clear Fluid Fast[NCT04625608] | Phase 4 | 104 participants (Anticipated) | Interventional | 2020-10-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for hydrochloric acid and Pneumonia, Aspiration
| Article | Year |
|---|---|
Effect of acidified enteral feedings on gastric colonization in the critically ill patient.
Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Critical Illness; Cross Infection; Double-Blind Method; E | 1992 |
The prophylactic use of antacids in the prevention of the acid-pulmonary-aspiration syndrome (Mendelson's syndrome).
Topics: Aluminum; Anesthesia, Obstetrical; Animals; Antacids; Bicarbonates; Bronchial Spasm; Female; Gastric | 1966 |
94 other studies available for hydrochloric acid and Pneumonia, Aspiration
| Article | Year |
|---|---|
Critical role of mitochondrial oxidative stress in acid aspiration induced ALI in mice.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Gene Ex | 2020 |
Vagotomy decreases the neuronal activities of medulla oblongata and alleviates neurogenic inflammation of airways induced by repeated intra-esophageal instillation of HCl in guinea pigs.
Topics: Animals; Capillary Permeability; Esophagus; Guinea Pigs; Hydrochloric Acid; Lung; Male; Medulla Oblo | 2017 |
N-acetyl-heparin attenuates acute lung injury caused by acid aspiration mainly by antagonizing histones in mice.
Topics: Acute Lung Injury; Analysis of Variance; Animals; Blood Gas Analysis; Blotting, Western; Heparin; Hi | 2014 |
Hydrochloric acid aspiration increases right ventricular systolic pressure in rats.
Topics: Anesthesia, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Endothe | 2009 |
Bosentan reduces oxidative burst in acid aspiration-induced lung injury in rats.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bosentan; Hydrochloric Acid; Male; Neutrophils | 2009 |
The effects of fenoterol inhalation after acid aspiration-induced lung injury.
Topics: Administration, Inhalation; Animals; Fenoterol; Hydrochloric Acid; Lung Injury; Male; Pneumonia, Asp | 2009 |
Exogenous surfactant instillation attenuates inflammatory response to acid-induced lung injury in rat.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Hydrochloric Acid; Lung; Male; Pneumonia, Aspi | 2010 |
Effects of pulmonary acid aspiration on the lungs and extra-pulmonary organs: a randomized study in pigs.
Topics: Animals; Extravascular Lung Water; Heart Conduction System; Hemodynamics; Hippocampus; Hydrochloric | 2012 |
Acid contact in the rodent pulmonary alveolus causes proinflammatory signaling by membrane pore formation.
Topics: Animals; Calcium Signaling; Cell Membrane; Edema; Epithelium; Fluoresceins; Fluorescent Dyes; Fura-2 | 2012 |
Acid-induced acute lung injury in mice is associated with P44/42 and c-Jun N-terminal kinase activation and requires the function of tumor necrosis factor α receptor I.
Topics: Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage; Caspase 3; Disease Models, Animal; En | 2012 |
Acid aspiration induces bacterial pneumonia by enhanced bacterial adherence in mice.
Topics: Animals; Bacterial Adhesion; Colony Count, Microbial; Hydrochloric Acid; Lung; Mice; Microscopy, Ele | 2002 |
Tracheobronchial stenosis from acid aspiration presenting as asthma.
Topics: Accidents, Occupational; Adult; Airway Obstruction; Asthma; Bronchial Diseases; Burns, Chemical; Con | 2003 |
[ANATOMOPATHOLOGICAL CHANGES OF THE LUNG IN SO-CALLED ASPIRATION BRONCHOPNEUMONIA].
Topics: Animals; Bronchopneumonia; Gastric Juice; Guinea Pigs; Hydrochloric Acid; Pathology; Pepsin A; Pneum | 1963 |
Experimental aspiration pneumonia. IV. Inflammatory and reparative changes produced by intratracheal injections of autologous gastric juice and hydrochloric acid.
Topics: Gastric Juice; Humans; Hydrochloric Acid; Injections; Pneumonia; Pneumonia, Aspiration | 1955 |
Elastase inhibition reduced death associated with acid aspiration-induced lung injury in hamsters.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibito | 2004 |
Effects of nitric oxide synthase inhibitor on acid aspiration-induced lung injury in rats.
Topics: Amidines; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Enzyme Inhibito | 2005 |
Early treatment with pentoxifylline reduces lung injury induced by acid aspiration in rats.
Topics: Animals; Burns, Chemical; Dose-Response Relationship, Drug; Hydrochloric Acid; Lung; Lung Injury; Ma | 2005 |
Surfactant alterations in acute inflammatory lung injury from aspiration of acid and gastric particulates.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage; Erythrocytes; Gastric Acid; Hydrochloric Acid; Infla | 2005 |
Activated protein C attenuates acid-aspiration lung injury in rats.
Topics: Albumins; Animals; Anticoagulants; Cell Count; Cytokines; Fibrin; Hemorrhage; Hydrochloric Acid; Leu | 2005 |
Acid and particulate-induced aspiration lung injury in mice: importance of MCP-1.
Topics: Animals; Chemokine CCL2; Cytokines; Granuloma; Hydrochloric Acid; Lung; Mice; Mice, Knockout; Pneumo | 2005 |
[Prophylactic effect of ambroxol on acute hydrochloric acid aspiration - induced lung injury].
Topics: Acute Lung Injury; Ambroxol; Animals; Disease Models, Animal; Expectorants; Female; Hydrochloric Aci | 2005 |
Inhibition of acid-induced lung injury by hyperosmolar sucrose in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cell Count; Disease Models, Animal; D | 2005 |
Effects of granulocyte colony-stimulating factor (G-CSF) and neutrophil elastase inhibitor (ONO-5046) on acid-induced lung injury in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Glycine; Granulocyte Colony-Stimulating Factor; Hydrochloric | 2004 |
The response to recruitment worsens with progression of lung injury and fibrin accumulation in a mouse model of acid aspiration.
Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Disease Progression; Fema | 2007 |
Lung injury and recovery in a murine model of unilateral acid aspiration: functional, biochemical, and morphologic characterization.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Female; Fibrosis; Hydrochloric Acid; Instillati | 2008 |
Synchronous versus asynchronous differential lung ventilation with PEEP after unilateral acid aspiration in the dog.
Topics: Animals; Computers; Dogs; Hemodynamics; Hydrochloric Acid; Pneumonia, Aspiration; Positive-Pressure | 1983 |
Differential lung ventilation with unilateral PEEP following unilateral hydrochloric acid aspiration in the dog.
Topics: Animals; Dogs; Hydrochloric Acid; Lung Diseases; Pneumonia, Aspiration; Positive-Pressure Respiratio | 1983 |
Failure of methylprednisolone, ibuprofen, or prostacyclin to reduce HCl-induced pulmonary albumin leak in dogs.
Topics: Albumins; Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Dogs; Epoprostenol; Hydro | 1984 |
Comparison of airway responses following tracheal or esophageal acidification in the cat.
Topics: Airway Resistance; Animals; Cats; Esophagitis; Esophagus; Female; Gastroesophageal Reflux; Hydrochlo | 1984 |
[Development of lung edema following endotracheal instillation of hydrochloric acid (aspiration pneumonitis model)].
Topics: Animals; Capillary Permeability; Disease Models, Animal; Dogs; Hydrochloric Acid; Pneumonia, Aspirat | 1984 |
Concentrated albumin does not affect lung edema formation after acid instillation in the dog.
Topics: Animals; Dogs; Female; Hydrochloric Acid; Male; Pneumonia, Aspiration; Pulmonary Edema; Serum Albumi | 1983 |
Pulmonary aspiration--effects of volume and pH in the rat.
Topics: Anesthesia, General; Animals; Hydrochloric Acid; Hydrogen-Ion Concentration; Pneumonia, Aspiration; | 1984 |
Aspiration pneumonia: treatment with pulmonary vasodilators.
Topics: Animals; Dogs; Hydrochloric Acid; In Vitro Techniques; Isoproterenol; Nitroprusside; Pneumonia, Aspi | 1983 |
[Anatomopathological aspects of aspiration pneumonia caused by hydrochloric acid. Experimental study in dogs].
Topics: Animals; Dogs; History, 20th Century; History, Ancient; Hydrochloric Acid; Lung; Male; Organ Size; P | 1981 |
Pulmonary acid injury: effects of positive end-expiratory pressure and crystalloid vs colloid fluid resuscitation.
Topics: Animals; Cardiac Output; Colloids; Dogs; Fluid Therapy; Hydrochloric Acid; Lung Compliance; Oxygen; | 1982 |
Failure of corticosteroid therapy for experimental acid aspiration.
Topics: Adrenal Cortex Hormones; Animals; Arteries; Body Water; Dogs; Female; Hydrochloric Acid; Lung; Male; | 1982 |
Aspiration pneumonitis. Correlation of experimental models with clinical disease.
Topics: Animals; Disease Models, Animal; Dogs; Gastric Acid; Humans; Hydrochloric Acid; Hydrogen-Ion Concent | 1982 |
[Pulmonary function in aspiration pneumonia. Experimental study in dogs].
Topics: Animals; Dogs; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Pneumonia, Aspiration; Respirati | 1981 |
Tracheal mucosal damage after aspiration. A scanning electron Microscope study.
Topics: Animals; Dogs; Gastric Juice; Hydrochloric Acid; Mice; Microscopy, Electron, Scanning; Mucous Membra | 1981 |
The pulmonary consequences of aspiration of gastric contents at pH values greater than 2.5.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Dogs; Food; Gastric Juice; Hydrochloric Acid; Hydrogen- | 1980 |
Aspiration-induced lung injury: role of complement.
Topics: Animals; Capillary Permeability; Complement Activation; Complement System Proteins; Disease Models, | 1995 |
[Effect of acid aspiration on right lymph duct lymph flow and prostaglandin metabolites in dogs].
Topics: Anesthesia, Intravenous; Animals; Capillary Permeability; Disease Models, Animal; Dogs; Hydrochloric | 1995 |
[Diffuse aspiration bronchiolitis (DAB) produced in animals by repeated HCl microaspiration].
Topics: Animals; Bronchiolitis; Disease Models, Animal; Hydrochloric Acid; Pneumonia, Aspiration; Rats; Rats | 1994 |
[An aspiration pneumonia in acute airway damage model induced by HCl and/or LPS].
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydrochloric Acid; Lip | 1993 |
Sucralfate does not reduce the risk of acid aspiration pneumonitis.
Topics: Airway Resistance; Animals; Digestive System; Disease Models, Animal; Drug Evaluation, Preclinical; | 1993 |
Leukocytes mediate acid aspiration-induced multiorgan edema.
Topics: Animals; Edema; Hydrochloric Acid; Hydrogen Peroxide; Kidney; Leukopenia; Lung; Male; Mechlorethamin | 1993 |
Surfactant treatment of respiratory failure induced by hydrochloric acid aspiration in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Hydrochloric Acid; Male; Pneumonia, Aspiration; Pulmonary Sur | 1993 |
Effects of acid aspiration-induced lung injury on left ventricular function.
Topics: Acid-Base Equilibrium; Animals; Blood Gas Analysis; Dogs; Extravascular Lung Water; Hemodynamics; Hy | 1996 |
Hypertonic saline treatment of acid aspiration-induced lung injury.
Topics: Animals; Bronchoalveolar Lavage Fluid; Hydrochloric Acid; Leukocyte Count; Lung; Oxygen; Peroxidase; | 1996 |
[The comparison of IRV and PEEP on gas exchanges in dogs with aspiration pneumonia].
Topics: Animals; Dogs; Hemodynamics; Hydrochloric Acid; Pneumonia, Aspiration; Positive-Pressure Respiration | 1997 |
Role of CD11b in focal acid-induced pneumonia and contralateral lung injury in rats.
Topics: Animals; CD18 Antigens; Cell Adhesion; Cell Movement; Disease Models, Animal; Endotoxins; Hydrochlor | 1998 |
Intravenous lidocaine attenuates acute lung injury induced by hydrochloric acid aspiration in rabbits.
Topics: Anesthetics, Local; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Dose-Response Relatio | 1998 |
Acid-induced lung injury. Protective effect of anti-interleukin-8 pretreatment on alveolar epithelial barrier function in rabbits.
Topics: Animals; Antibodies, Monoclonal; Biological Transport, Active; Capillary Permeability; Extravascular | 1999 |
Partial liquid ventilation decreases serum tumor necrosis factor-alpha concentrations in a rat acid aspiration lung injury model.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Causality; Disease Models, Animal; Drug Evaluation, Pre | 2000 |
Acid aspiration increases sensitivity to increased ambient oxygen concentrations.
Topics: Air; Animals; Drug Resistance; Hydrochloric Acid; Lung; Osmolar Concentration; Oxygen; Pneumonia, As | 2000 |
[Pretreatment of acid-induced lung injury with specific neutrophil elastase inhibitor ONO-5046 did not exasperate the subsequent bacterial lung infection by Pseudomonas aeruginosa].
Topics: Animals; Disease Models, Animal; Glycine; Hydrochloric Acid; Leukocyte Elastase; Male; Pneumonia, As | 2000 |
Acid exposure stimulates the adherence of Streptococcus pneumoniae to cultured human airway epithelial cells: effects on platelet-activating factor receptor expression.
Topics: Aged; Antibodies; Antioxidants; Azepines; Bacterial Adhesion; Cells, Cultured; Epithelial Cells; Fem | 2001 |
Sialyl Lewis(x) hybridized complement receptor type 1 moderates acid aspiration injury.
Topics: Animals; Cell Adhesion; Complement Activation; Complement Inactivator Proteins; Endothelium, Vascula | 2001 |
Outcome of acid ingestion related aspiration pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bronchoscopy; Burns, Chemical; Caustics; Digestive Syste | 2002 |
Bile aspiration: an experimental study in rabbits.
Topics: Animals; Bile; Bile Acids and Salts; Female; Hemorrhage; Hydrochloric Acid; Hydrogen-Ion Concentrati | 1975 |
Ventilation and blood-gas studies during experimentally produced Mendelson's syndrome in the dog.
Topics: Acidosis, Respiratory; Anesthesia, General; Animals; Carbon Dioxide; Disease Models, Animal; Dogs; F | 1975 |
Value of positive end-expiratory pressure in aspiration pneumonitis.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Bronchi; Cardiac Output; Dogs; Hemodynamics; Humans; Hy | 1978 |
Alveolar-capillary membrane permeability. Correlation with functional, radiographic, and postmortem changes after fluid aspiration.
Topics: Animals; Capillary Permeability; Cell Membrane Permeability; Hydrochloric Acid; Isotonic Solutions; | 1979 |
Antacid pulmonary aspiration in the dog.
Topics: Animals; Antacids; Dogs; Hydrochloric Acid; Pneumonia, Aspiration | 1979 |
[Current knowledge, diagnosis and therapy of Mendelson's syndrome].
Topics: Adult; Anti-Bacterial Agents; Diuretics; Humans; Hydrochloric Acid; Pneumonia, Aspiration; Respirati | 1979 |
Immediate histopathology of hydrochloric acid aspiration.
Topics: Animals; Disease Models, Animal; Dogs; Hemorrhage; Hydrochloric Acid; Lung Diseases; Male; Microcirc | 1979 |
[The lipids of the lungs in experimental aspiration pneumonitis (author's transl)].
Topics: Ambroxol; Animals; Cholesterol; Hydrochloric Acid; Lipids; Lung; Male; Phosphatidylcholines; Phospha | 1978 |
Effects of albumin and/or furosemide therapy on pulmonary edema induced by hydrochloric acid aspiration in rabbits.
Topics: Albumins; Animals; Exudates and Transudates; Furosemide; Hydrochloric Acid; Lung; Male; Oxygen; Pneu | 1976 |
Experimental acid-aspiration pneumonia in the rabbit. A pathologic and morphometric study.
Topics: Animals; Hydrochloric Acid; Inflammation; Lung; Male; Pneumonia, Aspiration; Rabbits; Vacuoles | 1976 |
Reactive oxygen species and elastase mediate lung permeability after acid aspiration.
Topics: Animals; Catalase; Evans Blue; Hydrochloric Acid; Lung; Male; Methacrylates; Neutrophils; Pancreatic | 1992 |
Haemodynamic effects of selective positive end-expiratory pressure after unilateral pulmonary hydrochloric acid-aspiration in dogs.
Topics: Animals; Cardiac Output; Disease Models, Animal; Dogs; Evaluation Studies as Topic; Functional Resid | 1992 |
Lung lavage and surfactant replacement for hydrochloric acid aspiration in rabbits.
Topics: Animals; Carbon Dioxide; Hydrochloric Acid; Hydrogen-Ion Concentration; Intubation, Intratracheal; L | 1990 |
Bronchial blood flow and eicosanoid blockade following airway acid aspiration.
Topics: Animals; Bronchial Arteries; Cyclooxygenase Inhibitors; Eicosanoids; Hydrochloric Acid; Ibuprofen; I | 1990 |
Chemotactic factor generation and cell accumulation in acute lung injury induced by endotracheal acid instillation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemotactic Factors; Complement C5; Complement C5 | 1989 |
Conjugated diene production after airway acid aspiration.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Female; Free Radicals; Hydrochloric Aci | 1989 |
The gastric juice aspiration syndrome (Mendelson syndrome). Aspects of pathogenesis and treatment in the pig.
Topics: Anesthesia, General; Animals; Benzodiazepinones; Buffers; Fluorescent Antibody Technique; Gastric Ju | 1986 |
[Gastroesophageal reflux in asthmatic and chronic bronchitis patients].
Topics: Adult; Aged; Asthma; Bronchitis; Chronic Disease; Diaphragm; Female; Gastroesophageal Reflux; Humans | 1988 |
Treatment of canine aspiration pneumonitis: fluid volume reduction vs. fluid volume expansion.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Hemodynamics; Hydrochloric Acid; Lung; Lung Complianc | 1988 |
Hemodynamic effects of nifedipine in a canine model of acid aspiration.
Topics: Animals; Disease Models, Animal; Dogs; Hemodynamics; Hydrochloric Acid; Nifedipine; Pneumonia, Aspir | 1988 |
Pulmonary and systemic consequences of localized acid aspiration.
Topics: Animals; Blood Gas Analysis; Dogs; Female; Hemodynamics; Hydrochloric Acid; Hypoxia; Leukocyte Count | 1986 |
Aspiration pneumonia: pulmonary arteriography after experimental aspiration.
Topics: Angiography; Animals; Dogs; Female; Hydrochloric Acid; Male; Pneumonia, Aspiration; Positive-Pressur | 1972 |
Aspiration pneumonia: physiologic data following experimental aspiration.
Topics: Animals; Blood Pressure; Carbon Dioxide; Dogs; Hematocrit; Hydrochloric Acid; Hydrogen-Ion Concentra | 1972 |
Experimental studies on aspiration of contents of obstructed intestine.
Topics: Airway Obstruction; Animals; Blood Pressure; Carbon Dioxide; Dogs; Endotoxins; Escherichia coli; Hem | 1972 |
The ineffectiveness of steroid therapy in treating aspiration of hydrochloric acid.
Topics: Animals; Blood Pressure; Carbon Dioxide; Dogs; Hydrochloric Acid; Methylprednisolone; Oxygen; Pneumo | 1974 |
Pulmonary aspiration of acid: an experimental study on cats.
Topics: Airway Resistance; Animals; Blood Pressure; Carbon Dioxide; Cats; Central Venous Pressure; Cross Cir | 1973 |
Possible treatment of aspiration pneumonia with bicarbonate solution.
Topics: Animals; Bicarbonates; Dogs; Hydrochloric Acid; Hydrogen-Ion Concentration; Injections; Oxygen; Pneu | 1972 |
An evaluation of steroid therapy in aspiration pneumonitis.
Topics: Animals; Bicarbonates; Blood; Bronchi; Carbon Dioxide; Cicatrix; Dogs; Hydrochloric Acid; Hydrogen-I | 1974 |
Steroid treatment for acid-aspiration pneumonitis.
Topics: Animals; Blood; Body Weight; Carbon Dioxide; Dexamethasone; Disease Models, Animal; Hydrochloric Aci | 1974 |
[Clinico-pathologico-anatomical changes in animals following instillation of gastric juice and diluted hydrochloric acid into the respiratory tract].
Topics: Animals; Gastric Juice; Hydrochloric Acid; Lung; Organ Size; Pneumonia, Aspiration; Rats | 1971 |
The acute effect of acid aspiration on lung mechanics and gas exchange in the rabbit.
Topics: Acidosis, Respiratory; Animals; Blood Pressure Determination; Carbon Dioxide; Disease Models, Animal | 1971 |
Aspiration pneumonia. Results of treatment by positive-pressure ventilation in dogs.
Topics: Animals; Blood; Carbon Dioxide; Dogs; Female; Hematocrit; Hydrochloric Acid; Hydrogen-Ion Concentrat | 1968 |
Cardiovascular effects of experimental aspiration pneumonia in dogs.
Topics: Animals; Aorta, Thoracic; Atropine; Blood Pressure; Blood Volume; Carbon Dioxide; Cardiac Output; Do | 1971 |
Hyperbaric oxygen therapy for chemical pneumonitis. Experimental and clinical observations.
Topics: Adolescent; Aged; Animals; Carbon Dioxide; Child, Preschool; Female; Humans; Hydrochloric Acid; Hydr | 1968 |
Pulmonary effects of experimental graded aspiration of hydrochloric acid.
Topics: Animals; Carbon Dioxide; Cardiac Output; Dogs; Hematocrit; Hydrochloric Acid; Hydrogen-Ion Concentra | 1969 |