hydrochloric acid has been researched along with Peptic Ulcer in 62 studies
Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
Excerpt | Relevance | Reference |
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"In order to explore secretory mechanisms in peptic ulcer, the plasma secretin response to an intraduodenal load of gastric acid stimulated with tetragastrin was studied in 10 patients with duodenal ulcer, nine with gastric ulcer, and five young healthy volunteers." | 3.66 | Effect of intraduodenal load of endogenous acid on secretin release in patients with peptic ulcer. ( Hamabe, S; Himeno, S; Kurokawa, M; Saito, R; Shima, K; Shinomura, Y; Takahashi, S; Tarui, S, 1982) |
"Pain is commonly the initial symptom in peptic ulcer, but the mechanism is controversial." | 2.37 | Ulcer pain mechanisms. The clinical features of active peptic ulcer disease and implications for therapy. ( Texter, EC, 1987) |
" This decrease was parallel with the simultaneous increase in the HBD and HCO3- secretion together with the increase in AGML in a dose-response manner." | 1.27 | [Mechanisms of gastric mucosal protection in peptic ulcer formation]. ( Nagamatsu, Y, 1988) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 55 (88.71) | 18.7374 |
1990's | 4 (6.45) | 18.2507 |
2000's | 3 (4.84) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
LeVEEN, HH | 1 |
Kimura, R | 1 |
Mahendran, P | 1 |
Sabitha, KE | 1 |
Devi, CS | 1 |
HIRVONEN, M | 1 |
SUNDBERG, M | 1 |
GLASS, GB | 1 |
SCHWARTZ, SA | 1 |
LISTER, J | 1 |
RICH, M | 1 |
SCHWARTZ, G | 1 |
HUNT, JN | 1 |
MARTIN, KA | 1 |
BEAL, JM | 1 |
GLENN, F | 1 |
LAMBLING, A | 1 |
BERTRAND, J | 1 |
BERNIER, JJ | 1 |
MARSHALL, EA | 1 |
SAMON, D | 1 |
PALMA, R | 1 |
ORREGO, H | 1 |
DEKKERS, HJ | 1 |
ZINNITZ, F | 1 |
HAMMER, O | 1 |
KLUGE, W | 1 |
FODOR, O | 2 |
MUNTEANU, P | 1 |
MARIN, F | 1 |
BOISSON, J | 1 |
MENGUY, R | 1 |
TEODORESCU, P | 1 |
SAVULESCU, V | 1 |
ANDRONACHE, I | 1 |
GANDARAMAZPULE, L | 1 |
RUIZOCHOA, V | 1 |
IENAGA, S | 1 |
CSALAY, L | 1 |
TOTH, E | 1 |
CLEAVE, TL | 1 |
GUPTA, OP | 1 |
SMALL, WP | 1 |
DEMLING, L | 1 |
OTTENJANN, R | 1 |
GEBHARDT, H | 1 |
KOROSTOVTSEV, SB | 1 |
GHAI, OP | 1 |
SINGH, M | 1 |
WALIA, BN | 1 |
GADEKAR, NG | 1 |
ARAI, T | 1 |
NECHELES, H | 1 |
PIRINOLI, M | 1 |
MAINIERO, D | 1 |
PALMER, ED | 1 |
ROMERO CALATAYUD, A | 1 |
TARAY ROMERO, J | 1 |
Le Veen, HH | 1 |
Hallinger, L | 1 |
Konturek, S | 1 |
Bahari, HM | 1 |
Ross, IN | 1 |
Turnberg, LA | 1 |
Kurokawa, M | 1 |
Saito, R | 1 |
Shinomura, Y | 1 |
Takahashi, S | 1 |
Hamabe, S | 1 |
Himeno, S | 1 |
Shima, K | 1 |
Tarui, S | 1 |
Toung, TJ | 1 |
Rosenfeld, BA | 1 |
Yoshiki, A | 1 |
Grayson, RF | 1 |
Traystman, RJ | 1 |
Sastry, MS | 1 |
Diwan, PV | 1 |
Krishna, DR | 1 |
Tariq, M | 1 |
Al Moutaery, AR | 1 |
Son, HJ | 1 |
Rhee, PL | 1 |
Kim, JJ | 1 |
Koh, KC | 1 |
Paik, SW | 1 |
Rhee, JC | 1 |
Tan, PV | 1 |
Nyasse, B | 1 |
Littman, A | 1 |
Welch, R | 1 |
Fruin, RC | 1 |
Aronson, AR | 1 |
Werner, B | 1 |
Balzer, M | 1 |
Tenge, M | 1 |
Oertel, W | 1 |
Wehling, H | 1 |
Rehner, M | 1 |
Soehendra, N | 1 |
James, O | 1 |
Kenefick, JS | 1 |
Valenzuela, JE | 1 |
Defilippi, C | 1 |
Starrett, JE | 1 |
Montzka, TA | 1 |
Crosswell, AR | 1 |
Cavanagh, RL | 1 |
Nagamatsu, Y | 1 |
Texter, EC | 1 |
Bates, RF | 1 |
Barlet, JP | 1 |
Koch, H | 1 |
Stolle, A | 1 |
Domschke, W | 1 |
Classen, M | 1 |
Rösch, W | 1 |
Vojtísek, V | 2 |
Jelínek, V | 2 |
Hradil, F | 1 |
Ivey, KJ | 1 |
Robert, A | 1 |
Stowe, DF | 1 |
Nezamis, JE | 1 |
Czarnecki, J | 1 |
Chlumská, A | 1 |
Brant, B | 1 |
Armstrong, RP | 1 |
Butz, RH | 1 |
Vetto, RM | 1 |
Wormsley, KG | 1 |
Delahunty, JE | 1 |
Ardran, GM | 1 |
Beach, FX | 1 |
Jones, ES | 1 |
Overholt, BF | 1 |
Pollard, HM | 1 |
Konturek, SJ | 1 |
Dubiel, J | 1 |
Gabryś, B | 1 |
Stirnemann, H | 1 |
2 reviews available for hydrochloric acid and Peptic Ulcer
Article | Year |
---|---|
Ulcer pain mechanisms. The clinical features of active peptic ulcer disease and implications for therapy.
Topics: Fluoroscopy; Gastric Acidity Determination; Gastrointestinal Motility; Humans; Hydrochloric Acid; Mo | 1987 |
Gastric mucosal barrier.
Topics: Aspirin; Atropine; Bile Acids and Salts; Biological Transport; Cell Membrane Permeability; Gastric A | 1971 |
2 trials available for hydrochloric acid and Peptic Ulcer
Article | Year |
---|---|
Hypersensitivity to acid in ulcer-like functional dyspepsia.
Topics: Adult; Dyspepsia; Female; Humans; Hydrochloric Acid; Male; Middle Aged; Pain; Peptic Ulcer | 1997 |
Controlled trials of aluminum hydroxide gels for peptic ulcer.
Topics: Aluminum Hydroxide; Analgesia; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer; Humans; Hy | 1977 |
58 other studies available for hydrochloric acid and Peptic Ulcer
Article | Year |
---|---|
Chemical, physiological, and pathological observations on the role of pepsin and hydrochloric acid in the production of experimental ulcers.
Topics: Hydrochloric Acid; Pepsin A; Peptic Ulcer; Ulcer | 1947 |
Can the use of exogenous acids prevent infection in patients treated with inhibitors of gastric acid secretion to prevent stress ulcers?
Topics: Citric Acid; Food, Formulated; Gastric Acid; Humans; Hydrochloric Acid; Peptic Ulcer; Stress, Psycho | 2002 |
Prevention of HCl-ethanol induced gastric mucosal injury in rats by Garcinia cambogia extract and its possible mechanism of action.
Topics: Animals; Anti-Ulcer Agents; Ethanol; Fruit; Garcinia cambogia; Gastric Acidity Determination; Gastri | 2002 |
[Studies of the effects of antrenyl on hydrochloric acid secretion].
Topics: Biological Transport; Digestion; Gastric Juice; Humans; Hydrochloric Acid; Oxyphenonium; Parasympath | 1954 |
Studies on the effect of robuden upon secretion of hydrochloric acid, pepsin and mucous substances in the stomach of patients with peptic ulcer, and upon peptic activity in vitro.
Topics: Gastrointestinal Hormones; Gastrointestinal Tract; Hydrochloric Acid; In Vitro Techniques; Pepsin A; | 1955 |
Influence of hydrochloric acid on gastric secretion and emptying in patients with duodenal ulcer.
Topics: Digestion; Duodenal Ulcer; Gastric Juice; Hydrochloric Acid; Leadership; Peptic Ulcer | 1957 |
The minor role of hydrochloric acid in experimental production of peptic ulcer in dogs.
Topics: Animals; Dogs; Hydrochloric Acid; Peptic Ulcer | 1957 |
[Variations in hydrochloric acid secretion as a function of the number of glandular cells in the fundus in gastroduodenal ulcers].
Topics: Digestion; Gastric Fundus; Gastric Juice; Hydrochloric Acid; Peptic Ulcer | 1958 |
The volume of N/10 hydrochloric acid neutralized per day in the treatment of peptic ulcer.
Topics: Antacids; Disease; Humans; Hydrochloric Acid; Mediastinal Diseases; Mediastinum; Peptic Ulcer | 1959 |
[Problems related to gastric intubation].
Topics: Achlorhydria; Digestive System Surgical Procedures; Humans; Hydrochloric Acid; Intubation; Peptic Ul | 1961 |
[The connection between pain and emptying of the stomach in duodenal ulcer patients, with hydrochloric acid determination during digestion].
Topics: Digestion; Duodenal Ulcer; Gastric Juice; Humans; Hydrochloric Acid; Pain; Peptic Ulcer; Stomach | 1960 |
[Autonomic nervous system, hydrochloric acid content of the stomach and circulatory volume of its wall].
Topics: Autonomic Nervous System; Catecholamines; Hydrochloric Acid; Peptic Ulcer | 1959 |
[Investigation of the dynamics of secretion of hydrochloric acid in the stomach and of pepsinogen for the diagnosis of ulcers].
Topics: Endopeptidases; Enzyme Precursors; Gastric Acidity Determination; Humans; Hydrochloric Acid; Pepsino | 1962 |
[Place of the hydrochloric acid-peptic theory in the pathogenesis of gastroduodenal ulcer. Deductions on the therapeutic plane].
Topics: Gastric Juice; Humans; Hydrochloric Acid; Peptic Ulcer | 1963 |
PATHOGENESIS OF MANN-WILLIAMSON ULCER. III. EFFECT OF EXCLUDING PANCREATIC OR BILIARY SECRETIONS FROM THE INTESTINE ON GASTRIC SECRETION AND LIVER FUNCTION.
Topics: Animals; Bile; Dogs; Gastric Juice; Histamine; Hydrochloric Acid; Intestinal Secretions; Intestines; | 1963 |
[PHARMACODYNAMIC TESTS IN THE DIAGNOSIS OF ULCEROUS DISEASE. I. VALUE OF SOME DIAGNOSTIC TESTS TO INDUCE ULCEROUS PAINS BY MOTOR AND SECRETORY FUNCTIONAL OVERLOAD].
Topics: Biological Transport; Diagnosis; Diagnostic Tests, Routine; Histamine; Hydrochloric Acid; Insulin; P | 1963 |
[PHYSIOPATHOLOGY OF HYDROCHLORIC ACID SECRETION. THE TEST OF MAXIMAL STIMULATION WITH HISTAMINE].
Topics: Achlorhydria; Gastric Acidity Determination; Gastric Juice; Histamine; Humans; Hydrochloric Acid; Pe | 1963 |
[ELECTRON MICROSCOPE OBSERVATIONS OF THE FINE STRUCTURE ALTERATIONS OF THE SURFACE EPITHELIAL CELLS OF THE PROXIMAL DIGESTIVE TRACT OF THE DOG INDUCED BY HYDROCHLORIC ACID].
Topics: Dogs; Duodenum; Electrons; Epithelial Cells; Gastric Mucosa; Hydrochloric Acid; Jejunum; Microscopy; | 1963 |
[ON THE MECHANISM OF THE ULCEROGENIC EFFECT OF BUTAZOLIDIN].
Topics: Adrenocorticotropic Hormone; Chlorothiazide; Histamine; Hydrochloric Acid; Peptic Ulcer; Phenylbutaz | 1963 |
[SEVERAL PROBLEMS CONCERNING THE PREULCEROUS PHASE OF PEPTIC ULCER].
Topics: Dyspepsia; Gastritis; Genetics, Medical; Histamine; Humans; Hydrochloric Acid; Peptic Ulcer; Peptic | 1964 |
A NEW APPROACH TO PEPTIC ULCER. I. PRESENTATION OF THE ARGUMENT.
Topics: Africa; Diet; Dietary Proteins; Digestion; Epidemiology; Food-Processing Industry; Humans; Hydrochlo | 1964 |
ESTIMATION OF GASTRIC PEPSIN IN THE DIAGNOSIS OF PEPTIC ULCER.
Topics: Biomedical Research; Chlorides; Clinical Laboratory Techniques; Duodenal Ulcer; Gastric Juice; Human | 1964 |
THE RECURRENCE OF ULCERATION AFTER SURGERY FOR DUODENAL ULCER.
Topics: Alcoholism; Duodenal Ulcer; Gastrectomy; Gastric Acidity Determination; Gastroenterostomy; Humans; H | 1964 |
[PANCREAS AND PEPTIC ULCER].
Topics: Bicarbonates; Duodenal Ulcer; Gastric Acidity Determination; Gastric Juice; Humans; Hydrochloric Aci | 1964 |
[DIAGNOSTIC ROLE OF FREE HYDROCHLORIC ACID DEBIT IN VARIOUS FORMS OF GASTRITIS AND PEPTIC ULCER].
Topics: Anti-Infective Agents, Local; Diagnosis; Gastric Acidity Determination; Gastritis; Humans; Hydrochlo | 1964 |
AN ASSESSMENT OF GASTRIC ACID SECRETORY RESPONSE WITH 'MAXIMAL' AUGMENTED HISTAMINE STIMULATION IN CHILDREN WITH PEPTIC ULCER.
Topics: Body Height; Body Weight; Child; Duodenal Ulcer; Gastric Acid; Gastric Acidity Determination; Histam | 1965 |
EFFECT OF ALTERNATING ACID AND ALKALINE DIGESTIVE FLUIDS ON THE GASTROINTESTINAL TRACT OF THE RAT.
Topics: Acid-Base Equilibrium; Acidosis; Bicarbonates; Duodenum; Esophagus; Hydrochloric Acid; Ileum; Jejunu | 1965 |
[The inhibition of gastric acidity by the action of anticholinergic agents. Comparative study of the action of methantheline bromide and isopropamide iodide on the chlorhydria or normal and ulcerous persons, by means of the carboxylic resin method of cati
Topics: Cations; Cholinergic Antagonists; Gastric Juice; Humans; Hydrochloric Acid; Ion Exchange; Methanthel | 1961 |
[Research on the rapidity of reduction of free hydrochloric acid in gastrectomy in relation to the primary site of ulcer].
Topics: Gastrectomy; Humans; Hydrochloric Acid; Peptic Ulcer; Research; Ulcer | 1950 |
The clinical significance of the small benign gastric ulcer with a note on benign ulcer of the greater curvature and in the absence of free hydrochloric acid.
Topics: Humans; Hydrochloric Acid; Peptic Ulcer; Stomach Ulcer; Ulcer | 1952 |
[Hydrochloric acid considered as a determining etiopathogenic factor in gastro duodenal ulcers].
Topics: Duodenal Ulcer; Humans; Hydrochloric Acid; Peptic Ulcer; Stomach | 1950 |
THE ROLE OF PEPSIN, PEPTIC INHIBITORY SUBSTANCES, AND HYDROCHLORIC ACID IN NORMAL SUBJECTS AND IN THE PRODUCTION OF PEPTIC ULCERS.
Topics: Digestion; Gastric Juice; Gastric Mucosa; Humans; Hydrochloric Acid; Pepsin A; Peptic Ulcer | 1947 |
[Clinical value of the maximal histamine test in association with conservative vagotomy].
Topics: Adolescent; Adult; Aged; Female; Gastric Acidity Determination; Gastritis; Histamine; Humans; Hydroc | 1967 |
Demonstration of a pH gradient across the mucus layer on the surface of human gastric mucosa in vitro.
Topics: Aspirin; Cystine; Gastric Mucosa; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Te | 1982 |
Effect of intraduodenal load of endogenous acid on secretin release in patients with peptic ulcer.
Topics: Adult; Duodenal Ulcer; Duodenum; Female; Gastric Acid; Gastrins; Humans; Hydrochloric Acid; Male; Mi | 1982 |
Sucralfate does not reduce the risk of acid aspiration pneumonitis.
Topics: Airway Resistance; Animals; Digestive System; Disease Models, Animal; Drug Evaluation, Preclinical; | 1993 |
Comparative evaluation of ulcer prevention efficacy of orally, rectally and sublingually administered omeprazole in three acute gastric ulcer models in rats.
Topics: Administration, Oral; Administration, Rectal; Administration, Sublingual; Animals; Aspirin; Female; | 1993 |
Gastric anti-ulcer and cytoprotective effect of l-serine in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Caustics; Dose-Response Relatio | 1997 |
Anti-ulcer compound from Voacanga africana with possible histamine H2 receptor blocking activity.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cameroon; Dose-Response Relationship, Drug; Duodenum; Ethan | 2000 |
[Morphology and physiopathology of Billroth I gastroduodenostomy].
Topics: Follow-Up Studies; Gastrectomy; Gastric Mucosa; Gastritis; Gastrointestinal Motility; Gastroscopy; H | 1976 |
Pain in peptic ulcer.
Topics: Endoscopy; Female; Humans; Hydrochloric Acid; Male; Pain; Peptic Ulcer | 1975 |
Pyloric-sphincter studies in peptic-ulcer patients: pylorus in peptic ulcer.
Topics: Adolescent; Adult; Aged; Female; Humans; Hydrochloric Acid; Male; Manometry; Middle Aged; Muscle Con | 1976 |
Synthesis and biological activity of 3-substituted imidazo[1,2-a]pyridines as antiulcer agents.
Topics: Animals; Anti-Ulcer Agents; Chemical Phenomena; Chemistry; Ethanol; Gastric Acid; Gastric Fistula; H | 1989 |
[Mechanisms of gastric mucosal protection in peptic ulcer formation].
Topics: Animals; Bicarbonates; Dinoprostone; Ethanol; Gastric Mucosa; Hydrochloric Acid; Male; Peptic Ulcer; | 1988 |
The preventive effect of porcine calcitonin given by mouth on restraint-induced gastric ulcer in rats.
Topics: Administration, Oral; Animals; Calcitonin; Fasting; Female; Gastric Juice; Gastrins; Hydrochloric Ac | 1974 |
[Effect of heparin on gastric and duodenal secretions].
Topics: Animals; Bicarbonates; Cats; Duodenum; Gastric Acidity Determination; Gastric Juice; Heparin; Humans | 1972 |
[Therapeutic problems of chronic gastroenterologic diseases].
Topics: Aluminum Hydroxide; Chronic Disease; Gastritis; Gastroesophageal Reflux; Gastrointestinal Diseases; | 1973 |
[Experimental peptic ulcer in rats].
Topics: Animals; Disease Models, Animal; Female; Gastric Mucosa; Hydrochloric Acid; Male; Methods; Peptic Ul | 1972 |
Possible relationship between smoking and peptic ulcer.
Topics: Animals; Drug Synergism; Female; Hydrochloric Acid; Injections, Subcutaneous; Nicotine; Peptic Ulcer | 1971 |
[Studies on the 24 hour urinary excretion of 5-hydroxyindoleacetic acid in patients with stomach or duodenal ulcer before, during and after treatment with Spasmophen in relation to the "basal HC1 excretion" and the clinical condition of patients].
Topics: Humans; Hydrochloric Acid; Hydroxyindoleacetic Acid; Oxyphenonium; Parasympatholytics; Peptic Ulcer | 1968 |
Experimental gastroduodenal ulcer.
Topics: Animals; Disease Models, Animal; Dogs; Duodenum; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; M | 1971 |
The diagnosis of esophagitis in surgical patients.
Topics: Adult; Aged; Esophagitis; Esophagitis, Peptic; Female; Gastrectomy; Hernia, Diaphragmatic; Humans; H | 1970 |
Response to duodenal acidification in man. II. Effects on the gastric secretory response to pentagastrin.
Topics: Adult; Gastric Juice; Gastric Mucosa; Hernia, Inguinal; Humans; Hydrochloric Acid; Male; Middle Aged | 1970 |
Globus hystericus--a manifestation of reflux oesophagitis?
Topics: Adult; Barium Sulfate; Female; Fluoroscopy; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; | 1970 |
Metabolic alkalosis treated with intravenous hydrochloric acid.
Topics: Alkalosis; Humans; Hydrochloric Acid; Injections, Intravenous; Male; Middle Aged; Pancreatitis; Pept | 1971 |
Acid diffusion into the human gastric mucosa.
Topics: Achlorhydria; Acids; Adult; Cell Membrane Permeability; Duodenal Ulcer; Female; Gastric Acidity Dete | 1968 |
Effect of exclusion, acidification, and excision of the duodenum on gastric acid secretion and the production of pentagastrin-induced peptic ulcer in cats.
Topics: Animals; Bile; Cats; Duodenum; Gastric Juice; Gastrins; Hydrochloric Acid; Hydrogen-Ion Concentratio | 1969 |
[Studies on the origin of acute posttraumatic peptic ulcer].
Topics: Brain; Brain Injuries; Gastric Acidity Determination; Histamine; Humans; Hydrochloric Acid; Peptic U | 1966 |