Page last updated: 2024-10-17

hydrochloric acid and Heartburn

hydrochloric acid has been researched along with Heartburn in 53 studies

Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.

Heartburn: Substernal pain or burning sensation, usually associated with regurgitation of gastric juice into the esophagus.

Research Excerpts

ExcerptRelevanceReference
"The intensity of heartburn symptom in response to esophageal acid infusion was significantly greater with baclofen than the placebo (P = 0."9.30Gamma-aminobutyric acid receptor type B agonist baclofen inhibits acid-induced excitation of secondary peristalsis but not heartburn sensation. ( Chen, CL; Hung, JS; Lei, WY; Liu, TT; Wong, MW; Yi, CH, 2019)
"In a randomized double-blind crossover study, we perfused the esophagus with amiloride or (saline) placebo prior to eliciting acid-induced heartburn in patients with a history of proton pump inhibitor-responsive NERD."9.17Effect of amiloride on experimental acid-induced heartburn in non-erosive reflux disease. ( Bulsiewicz, WJ; Hansen, MB; Orlando, RC; Pruitt, A; Shaheen, NJ, 2013)
"The intensity of heartburn symptom in response to esophageal acid infusion was significantly greater with baclofen than the placebo (P = 0."5.30Gamma-aminobutyric acid receptor type B agonist baclofen inhibits acid-induced excitation of secondary peristalsis but not heartburn sensation. ( Chen, CL; Hung, JS; Lei, WY; Liu, TT; Wong, MW; Yi, CH, 2019)
"In a randomized double-blind crossover study, we perfused the esophagus with amiloride or (saline) placebo prior to eliciting acid-induced heartburn in patients with a history of proton pump inhibitor-responsive NERD."5.17Effect of amiloride on experimental acid-induced heartburn in non-erosive reflux disease. ( Bulsiewicz, WJ; Hansen, MB; Orlando, RC; Pruitt, A; Shaheen, NJ, 2013)
"The intensity of heartburn symptom subsequent to acid infusion was significantly reduced after capsaicin infusion as compared with saline infusion (54 ± 3 vs 61 ± 3; P = 0."3.83Effects of esophageal capsaicin instillation on acid induced excitation of secondary peristalsis in humans. ( Chen, CL; Hung, JS; Lei, WY; Liu, TT; Orr, WC; Yi, CH, 2016)
"The administration of capsaicin induced a significant increase in the visual analogue scale score for heartburn as compared with hydrochloric acid (P = 0."3.79Comparable effects of capsaicin-containing red pepper sauce and hydrochloric acid on secondary peristalsis in humans. ( Chen, CL; Liu, TT; Yi, CH, 2013)
"Twelve healthy controls and 39 patients with reflux disease [14 erosive reflux disease, 11 non-erosive reflux disease with normal (functional heartburn) and 14 non-erosive reflux disease with excess acid exposure] had hydrochloric acid and saline infused into distal and then proximal oesophagus."3.74Acid-related oesophageal sensitivity, not dysmotility, differentiates subgroups of patients with non-erosive reflux disease. ( Emmanuel, AV; Kalantzis, C; Khoo, D; Thoua, NM, 2008)
"To examine the relationship between esophageal acid exposure and development of salivation and heartburn, 15 healthy subjects underwent perfusion of the distal esophagus with varying concentrations of hydrochloric acid, different-osmolality saline solutions, and deionized water."3.68Modulation of salivary secretion by acid infusion in the distal esophagus in humans. ( Dutta, SK; Matossian, HB; Meirowitz, RF; Vaeth, J, 1992)
"Heartburn is commonly associated with the presence of acid in the oesophageal lumen."2.77Oesophageal sensation in response to high PCO(2) and acidic solutions in nonerosive reflux disease. ( Akiba, Y; Ashpole, N; Fass, OZ; Fass, R; Guillén-Rodríguez, JM; Hershcovici, T; Kaunitz, JD; Poh, CH, 2012)
"Most patients with cough and gastroesophageal reflux disease (GERD) improve on medical treatment with proton pump inhibitors (PPI)."2.70Preoperative symptom evaluation and esophageal acid infusion predict response to laparoscopic Nissen fundoplication in gastroesophageal reflux patients who present with cough. ( Allen, CJ; Anvari, M, 2002)
"Fifteen consecutive patients with systemic sclerosis and six healthy subjects underwent oesophageal manometry and an acid clearance test in three body positions (supine, recumbent at 30 degrees and seated at 90 degrees) in randomized order."2.68Oesophageal acid clearance in patients with systemic sclerosis: effect of body position. ( Barbera, R; Basilisco, G; Bianchi, P; Carola, F; Vanoli, M, 1996)
"GERDQ was negatively correlated to lag time (r = -."1.51Esophageal acid sensitivity in patients with gastroesophageal reflux disease: Does esophageal hypomotility matter? ( Chen, CL; Hung, JS; Lei, WY; Liu, TT; Wong, MW; Yi, CH, 2019)
"The pathogenesis of gastro-oesophageal reflux disease includes increased acid reflux, reduced salivation and impaired peristalsis."1.36Modulation of salivation and heartburn in response to the site of acid infusion in the human oesophagus. ( Agrawal, K; Dutta, SK; Mahmoud, MA, 2010)
"A total of 12 GERD patients (six male, six female; mean age 37."1.32Autonomic responses to heartburn induced by esophageal acid infusion. ( Chen, CL; Orr, WC, 2004)
"Patients with gastro-oesophageal reflux disease (GORD) frequently report that meals high in fat worsen heartburn."1.31Duodenal fat intensifies the perception of heartburn. ( Elashoff, JD; Fass, R; Lembo, A; Mayer, EA; Meyer, JH, 2001)
"Primary symptoms include dysphagia, odynophagia, heartburn and central chest pain."1.27Evaluation of esophageal diseases. ( Dabaghi, RE; Scott, LD, 1986)
"the pain has been analyzed to determine its characteristic and its atypical features."1.26Characteristics of esophageal pain. ( Henderson, RD; Marryatt, G, 1981)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199020 (37.74)18.7374
1990's7 (13.21)18.2507
2000's11 (20.75)29.6817
2010's15 (28.30)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wong, MW2
Hung, JS3
Lei, WY3
Liu, TT6
Yi, CH6
Chen, CL7
Bulsiewicz, WJ1
Shaheen, NJ1
Hansen, MB1
Pruitt, A1
Orlando, RC1
Forcelini, CM1
Tomiozzo, JC1
Farré, R1
Van Oudenhove, L1
Callegari-Jacques, SM1
Ribeiro, M1
Madalosso, BH1
Fornari, F1
Orr, WC3
van Hoeij, FB1
Weijenborg, PW1
van den Bergh Weerman, MA1
van den Wijngaard, RM1
Verheij, J1
Smout, AJ1
Bredenoord, AJ1
Yang, M2
Li, ZS2
Chen, DF1
Zou, DW2
Xu, XR2
Fang, DC2
Xu, GM2
Stephens, RL1
Wang, ZG1
Dutta, SK2
Agrawal, K1
Mahmoud, MA1
Kobayashi, S1
Abe, Y1
Tashiro, M1
Koike, T1
Iijima, K1
Imatani, A1
Ohara, S1
Watanabe, S1
Fukudo, S1
Shimosegawa, T1
Hershcovici, T1
Poh, CH1
Fass, OZ1
Ashpole, N1
Akiba, Y1
Guillén-Rodríguez, JM1
Kaunitz, JD1
Fass, R3
Szczesniak, MM1
Fuentealba, SE1
Cook, IJ1
Kondo, T1
Oshima, T1
Tomita, T1
Fukui, H1
Watari, J1
Okada, H1
Kikuchi, S1
Sasako, M1
Matsumoto, T1
Knowles, CH1
Miwa, H1
Allen, CJ1
Anvari, M1
Vantrappen, G1
Tack, J1
Huyberechts, G1
Sifrim, D1
Geboes, K1
Janmsens, J1
Van Overstraeten, R1
SIEGEL, CI1
HENDRIX, TR1
Bhalla, V1
Liu, J1
Puckett, JL1
Mittal, RK1
Siddiqui, A1
Rodriguez-Stanley, S3
Zubaidi, S2
Miner, PB3
Sun, ZX1
Tu, ZX1
Shapiro, M1
Green, C1
Bautista, JM1
Peru, RL1
Malagon, IB1
Corvo, M1
Risner-Adler, S1
Beeler, JN1
Tuchinsky, I1
Bemben, D1
Redinger, N1
Thoua, NM1
Khoo, D1
Kalantzis, C1
Emmanuel, AV1
Henderson, RD1
Marryatt, G1
Winnan, GR1
Meyer, CT1
McCallum, RW1
López Gastón, AR1
Andrüsh, A1
Tiberio, GD1
López de Luise, G1
Curcio, A1
Brown, CM1
Snowdon, CF1
Slee, B1
Sandle, LN1
Rees, WD1
Johnston, BT1
Collins, JS1
McFarland, RJ1
Love, AH1
Basilisco, G1
Carola, F1
Vanoli, M1
Bianchi, P1
Barbera, R1
Robinson, M1
Earnest, DL1
Greenwood-Van Meerveld, B1
Meyer, JH1
Lembo, A1
Elashoff, JD1
Mayer, EA1
Mangano, M1
Colombo, P1
Bianchi, PA1
Penagini, R1
Atlay, RD1
Weekes, AR1
Entwistle, GD1
Parkinson, DJ1
Behar, J1
Bachir, GS1
Collis, JL1
Matossian, HB1
Meirowitz, RF1
Vaeth, J1
Howard, PJ1
Maher, L1
Pryde, A1
Heading, RC1
Dabaghi, RE1
Scott, LD1
Richter, JE1
Johns, DN1
Wu, WC1
Castell, DO3
Kjellén, G1
Tibbling, L1
Brügmann, E1
Hauzeur, F1
McCall, IW1
Davies, ER1
Delahunty, JE1
de Moraes-Filho, JP1
Stanciu, C1
Bennett, JR2
Spencer, J1
Crozier, RE1
Gregg, JA1
Garabedian, MM1
De la Revilla, L1
Martin-Vivaldi, R1
Ventin, JL1
Hernandez, L1
Levine, SM1
Rudolph, I1
Herrera, AF1
Stein, GN1
Roth, JL1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of a Dietary Supplement for Reflux During Sleep[NCT02274636]50 participants (Anticipated)Interventional2014-10-31Not yet recruiting
Evaluation of Esophageal and Gastric Acid Levels in Patients Presenting With Upper Gastrointestinal Symptoms Using a Novel PH System[NCT00579410]85 participants (Actual)Observational2004-05-31Completed
A Clinical Study of Demographics and Findings During Endoscopy in Patients With Abdominal Pain, Dyspepsia, GERD, and Associated Symptoms[NCT00576992]1,177 participants (Actual)Observational2003-01-31Terminated (stopped due to Recruitment not being met)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrochloric acid and Heartburn

ArticleYear
Reflux esophagitis: pathogenesis, diagnosis, and management.
    Archives of internal medicine, 1976, Volume: 136, Issue:5

    Topics: Antacids; Biopsy; Esophagitis, Peptic; Esophagogastric Junction; Esophagoscopy; Gastrins; Heartburn;

1976

Trials

14 trials available for hydrochloric acid and Heartburn

ArticleYear
Gamma-aminobutyric acid receptor type B agonist baclofen inhibits acid-induced excitation of secondary peristalsis but not heartburn sensation.
    Journal of gastroenterology and hepatology, 2019, Volume: 34, Issue:2

    Topics: Adult; Baclofen; Double-Blind Method; Esophageal Motility Disorders; Esophagus; Female; GABA-B Recep

2019
Effect of amiloride on experimental acid-induced heartburn in non-erosive reflux disease.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:7

    Topics: Acid Sensing Ion Channel Blockers; Administration, Topical; Adolescent; Adult; Aged; Amiloride; Cros

2013
Effect of nortriptyline on brain responses to painful esophageal acid infusion in patients with non-erosive reflux disease.
    Neurogastroenterology and motility, 2014, Volume: 26, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Brain; Brain Mapping; Cross-Over Studies; Double-Blind Meth

2014
Brain activity following esophageal acid infusion using positron emission tomography.
    World journal of gastroenterology, 2010, Nov-21, Volume: 16, Issue:43

    Topics: Adult; Brain; Gyrus Cinguli; Heartburn; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Incid

2010
Oesophageal sensation in response to high PCO(2) and acidic solutions in nonerosive reflux disease.
    European journal of clinical investigation, 2012, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbon Dioxide; Case-Control Studies; Cross-Over Studies

2012
Acid sensitization of esophageal mucosal afferents: implication for symptom perception in patients across the gastroesophageal reflux disease spectrum.
    The Clinical journal of pain, 2013, Volume: 29, Issue:1

    Topics: Adult; Afferent Pathways; Aged; Esophagus; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydro

2013
Prostaglandin E(2) mediates acid-induced heartburn in healthy volunteers.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Mar-15, Volume: 304, Issue:6

    Topics: Administration, Mucosal; Adult; Biopsy; Esophagoscopy; Esophagus; Heartburn; Humans; Hydrochloric Ac

2013
Influence of intraluminal acidification on esophageal secondary peristalsis in humans.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:7

    Topics: Adult; Double-Blind Method; Esophagus; Female; Heartburn; Humans; Hydrochloric Acid; Insufflation; M

2013
Preoperative symptom evaluation and esophageal acid infusion predict response to laparoscopic Nissen fundoplication in gastroesophageal reflux patients who present with cough.
    Surgical endoscopy, 2002, Volume: 16, Issue:7

    Topics: Cough; Double-Blind Method; Esophagus; Female; Follow-Up Studies; Fundoplication; Gastroesophageal R

2002
Effect of esophageal acid and prophylactic rabeprazole on performance in runners.
    Medicine and science in sports and exercise, 2006, Volume: 38, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Esophagus; Exercise Test; Female;

2006
Interpretation of the Bernstein test: a reappraisal of criteria.
    Annals of internal medicine, 1982, Volume: 96, Issue:3

    Topics: Adult; Antacids; Evaluation Studies as Topic; Gastroesophageal Reflux; Heartburn; Humans; Hydrochlor

1982
Oesophageal acid clearance in patients with systemic sclerosis: effect of body position.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Deglutition; Deglutition Disorders; Esophageal Motility Disorders; Esophagi

1996
Fat and esophageal sensitivity to acid.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:3

    Topics: Adult; Dietary Fats; Drug Combinations; Esophagus; Gastroesophageal Reflux; Glycerol; Heartburn; Hum

2002
Treating heartburn in pregnancy: comparison of acid and alkali mixtures.
    British medical journal, 1978, Sep-30, Volume: 2, Issue:6142

    Topics: Bicarbonates; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Heartburn; H

1978

Other Studies

38 other studies available for hydrochloric acid and Heartburn

ArticleYear
Esophageal acid sensitivity in patients with gastroesophageal reflux disease: Does esophageal hypomotility matter?
    Neurogastroenterology and motility, 2019, Volume: 31, Issue:11

    Topics: Adult; Aged; Esophageal Motility Disorders; Esophageal pH Monitoring; Female; Gastroesophageal Reflu

2019
Comparable effects of capsaicin-containing red pepper sauce and hydrochloric acid on secondary peristalsis in humans.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:11

    Topics: Adult; Capsaicin; Capsicum; Esophagus; Female; Heartburn; Humans; Hydrochloric Acid; Male; Manometry

2013
Effects of esophageal capsaicin instillation on acid induced excitation of secondary peristalsis in humans.
    Journal of gastroenterology and hepatology, 2016, Volume: 31, Issue:2

    Topics: Adult; Air; Capsaicin; Esophagus; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric A

2016
Mucosal integrity and sensitivity to acid in the proximal esophagus in patients with gastroesophageal reflux disease.
    American journal of physiology. Gastrointestinal and liver physiology, 2016, 07-01, Volume: 311, Issue:1

    Topics: Adult; Aged; Biopsy; Electric Impedance; Esophageal Mucosa; Esophagoscopy; Female; Gastric Acid; Gas

2016
Quantitative assessment and characterization of visceral hyperalgesia evoked by esophageal balloon distention and acid perfusion in patients with functional heartburn, nonerosive reflux disease, and erosive esophagitis.
    The Clinical journal of pain, 2010, Volume: 26, Issue:4

    Topics: Acids; Adult; Analysis of Variance; Catheterization; Esophageal pH Monitoring; Esophagitis, Peptic;

2010
Altered sensorimotor responses to esophageal acidification in older adults with GERD.
    Scandinavian journal of gastroenterology, 2010, Volume: 45, Issue:10

    Topics: Adult; Age Factors; Aged; Aging; Esophageal pH Monitoring; Esophagoscopy; Esophagus; Female; Gastroe

2010
Modulation of salivation and heartburn in response to the site of acid infusion in the human oesophagus.
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:6

    Topics: Adult; Esophagus; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Hydrogen-Ion Concen

2010
Studies on the relationship between esophageal acid exposure, mucosal lesions and heartburn using an acid exposure sensor.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:11

    Topics: Adult; Animals; Cats; Diagnostic Techniques, Digestive System; Esophageal Diseases; Esophagus; Femal

2002
Esophageal motor abnormalities induced by acid perfusion in patients with heartburn.
    The Journal of clinical investigation, 1963, Volume: 42

    Topics: Deglutition Disorders; Digestive System; Esophagitis; Heartburn; Humans; Hydrochloric Acid; Perfusio

1963
Symptom hypersensitivity to acid infusion is associated with hypersensitivity of esophageal contractility.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:1

    Topics: Adult; Esophageal Diseases; Esophagus; Female; Heartburn; Humans; Hydrochloric Acid; Male; Manometry

2004
Autonomic responses to heartburn induced by esophageal acid infusion.
    Journal of gastroenterology and hepatology, 2004, Volume: 19, Issue:8

    Topics: Adult; Autonomic Nervous System; Case-Control Studies; Female; Gastroesophageal Reflux; Heart Rate;

2004
Esophageal visceral sensitivity to bile salts in patients with functional heartburn and in healthy control subjects.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:1

    Topics: Adult; Case-Control Studies; Catheterization; Chenodeoxycholic Acid; Esophagus; Female; Gastrointest

2005
Characterization of cortical potentials evoked by oesophageal balloon distention and acid perfusion in patients with functional heartburn.
    Neurogastroenterology and motility, 2006, Volume: 18, Issue:4

    Topics: Adult; Aged; Cerebral Cortex; Dilatation; Electroencephalography; Esophagus; Evoked Potentials, Soma

2006
Functional heartburn patients demonstrate traits of functional bowel disorder but lack a uniform increase of chemoreceptor sensitivity to acid.
    The American journal of gastroenterology, 2006, Volume: 101, Issue:5

    Topics: Autonomic Nervous System; Bacterial Proteins; Chemoreceptor Cells; Endoscopy, Gastrointestinal; Esop

2006
Acid-related oesophageal sensitivity, not dysmotility, differentiates subgroups of patients with non-erosive reflux disease.
    Alimentary pharmacology & therapeutics, 2008, Mar-01, Volume: 27, Issue:5

    Topics: Adult; Case-Control Studies; Esophageal Motility Disorders; Esophagoscopy; Female; Gastroesophageal

2008
Characteristics of esophageal pain.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 644

    Topics: Diagnosis, Differential; Food; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Pain;

1981
["Mechano-" and "chemo-sensitive" esophagus. Investigation of non-cardiac chest pain using intraesophageal balloon test and acid perfusion].
    Acta gastroenterologica Latinoamericana, 1994, Volume: 24, Issue:4

    Topics: Adult; Aged; Case-Control Studies; Catheterization; Chest Pain; Esophagus; Female; Heartburn; Humans

1994
Effect of topical oesophageal acidification on human salivary and oesophageal alkali secretion.
    Gut, 1995, Volume: 36, Issue:5

    Topics: Administration, Topical; Adult; Bicarbonates; Dose-Response Relationship, Drug; Esophagus; Female; H

1995
Are esophageal symptoms reflux-related? A study of different scoring systems in a cohort of patients with heartburn.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:4

    Topics: Cohort Studies; Endoscopy, Digestive System; Esophagitis, Peptic; Female; Gastroesophageal Reflux; H

1994
Esophageal hypersensitivity may be a major cause of heartburn.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:3

    Topics: Adult; Aged; Chronic Disease; Esophagoscopy; Esophagus; Female; Heartburn; Humans; Hydrochloric Acid

1999
Duodenal fat intensifies the perception of heartburn.
    Gut, 2001, Volume: 49, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Anti-Ulcer Agents; Dietary Fats; Dose-Response Relationship, Drug

2001
Effect of perfusion of bile salts solutions into the oesophagus of hiatal hernia patients and controls.
    Thorax, 1976, Volume: 31, Issue:3

    Topics: Bile Acids and Salts; Esophagitis; Esophagus; Heartburn; Hernia, Diaphragmatic; Hernia, Hiatal; Huma

1976
Modulation of salivary secretion by acid infusion in the distal esophagus in humans.
    Gastroenterology, 1992, Volume: 103, Issue:6

    Topics: Adult; Bicarbonates; Esophagitis; Esophagus; Heartburn; Humans; Hydrochloric Acid; Hydrogen-Ion Conc

1992
Symptomatic gastro-oesophageal reflux, abnormal oesophageal acid exposure, and mucosal acid sensitivity are three separate, though related, aspects of gastro-oesophageal reflux disease.
    Gut, 1991, Volume: 32, Issue:2

    Topics: Adult; Chest Pain; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Hydrogen-I

1991
Evaluation of esophageal diseases.
    American family physician, 1986, Volume: 33, Issue:1

    Topics: Barium Sulfate; Deglutition Disorders; Endoscopy; Esophageal Diseases; Esophagus; Fiber Optic Techno

1986
Are esophageal motility abnormalities produced during the intraesophageal acid perfusion test?
    JAMA, 1985, Apr-05, Volume: 253, Issue:13

    Topics: Adult; Deglutition; Esophagus; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Manome

1985
Oesophageal motility during acid-provoked heartburn and chest pain.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:8

    Topics: Adult; Aged; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Reflux; Gastrointestinal

1985
[Esophageal symptoms and their relationships to the result of the perfusion test and to the histological mucosal finding in the esophagus].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Apr-01, Volume: 29, Issue:7

    Topics: Biopsy; Duodenal Ulcer; Esophagitis; Esophagus; Heartburn; Hernia, Diaphragmatic; Humans; Hydrochlor

1974
The acid-barium test as an index of intermittent gastro-oesophageal reflux.
    The British journal of radiology, 1973, Volume: 46, Issue:548

    Topics: Barium Sulfate; Deglutition; Fluoroscopy; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric A

1973
Editorial: Acid perfusion revisited.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:9

    Topics: Duodenal Ulcer; Esophagitis, Peptic; Gastritis; Heartburn; Humans; Hydrochloric Acid; Perfusion

1974
Lack of specificity of the acid perfusion test in duodenal ulcer patients.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:9

    Topics: Adult; Duodenal Ulcer; Duodenum; Esophagitis, Peptic; Esophagoscopy; Esophagus; Evaluation Studies a

1974
Upper oesophageal sphincter yield pressure in normal subjects and in patients with gastro-oesophageal reflux.
    Thorax, 1974, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aged; Catheterization; Esophagitis; Esophagoscopy; Esophagus; Female; Gastroesoph

1974
Hiatus hernia and oesophageal reflux. Methods of investigation. I.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:1

    Topics: Biopsy; Esophagitis; Esophagoscopy; Esophagus; Gastric Acidity Determination; Gastric Juice; Gastroe

1972
Obscure chest pain as a symptom of reflux esophagitis.
    The Medical clinics of North America, 1972, Volume: 56, Issue:3

    Topics: Adult; Aged; Deglutition Disorders; Endoscopy; Esophagitis; Female; Gastroesophageal Reflux; Gastroi

1972
[Esophageal acid instillation test in pregnant women with pyrosis].
    Revista espanola de las enfermedades del aparato digestivo, 1971, Jun-15, Volume: 34, Issue:6

    Topics: Adult; Esophagus; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Methods; Pe

1971
Lower esophageal sphincter response to gastric alkalinization. A new mechanism for treatment of heartburn with antacids.
    Annals of internal medicine, 1971, Volume: 74, Issue:2

    Topics: Alkalies; Antacids; Bicarbonates; Esophagogastric Junction; Gastric Mucosa; Gastrins; Heartburn; Hum

1971
Mechanism of pyrosis. A clinical study.
    The American journal of digestive diseases, 1971, Volume: 16, Issue:7

    Topics: Gastric Acidity Determination; Gastroesophageal Reflux; Gastrointestinal Motility; Heartburn; Hernia

1971
Oesophageal pain.
    Postgraduate medical journal, 1968, Volume: 44, Issue:514

    Topics: Diagnosis, Differential; Esophagitis; Heartburn; Humans; Hydrochloric Acid; Methods; Perfusion

1968