hydrochloric acid has been researched along with Esophagitis, Reflux in 57 studies
Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Upper gastrointestinal endoscopy and radiologic examination were performed in 101 patients with symptoms strongly suggestive of gastroesophageal reflux (GER) disease." | 3.67 | Hiatus hernia in gastroesophageal reflux disease. ( Grette, K; Halvorsen, T; Kaul, B; Myrvold, HE; Petersen, H; Røysland, P, 1986) |
| "Gastroesophageal reflux disease (GERD) has been linked to a number of extra-esophageal symptoms and disorders, primarily in the respiratory tract." | 1.36 | A novel external esophageal perfusion model for reflux-associated respiratory symptoms. ( Kang, J; Kong, L; Li, Q; Liu, X; Wang, J; Zhang, S; Zhong, Z, 2010) |
| " The rats were divided into six groups after operations at random, which were fed up respectively with Tongjiang granule of different dosage and perpulsid." | 1.33 | [Study on reflux esophagitis treated by Tongjiang granule]. ( Hu, YC; Shao, Y; Tang, XD; Wang, ZB; Wu, HM, 2006) |
| "We conclude that gastroesophageal reflux contributes little to the nocturnal worsening of asthma." | 1.28 | Effects of spontaneous and simulated gastroesophageal reflux on sleeping asthmatics. ( Ballard, RD; Martin, RJ; Pandey, R; Tan, WC, 1990) |
| "Patients with Barrett's esophagus had sensitivity to esophageal acid perfusion less frequently than those with uncomplicated reflux esophagitis (66 vs." | 1.27 | Esophageal acid sensitivity in Barrett's esophagus. ( Cattau, EL; Chobanian, SJ; Johnson, DA; Spurling, TJ; Winters, C, 1987) |
| "Clinically, a gastro-esophageal reflux was found in 72% of the cases." | 1.26 | [Comparison of the value of various methods for diagnosis of gastroesophageal reflux]. ( Junginger, T; Pichlmaier, H; Trost, A, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (59.65) | 18.7374 |
| 1990's | 12 (21.05) | 18.2507 |
| 2000's | 8 (14.04) | 29.6817 |
| 2010's | 3 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Honda, J | 1 |
| Iijima, K | 1 |
| Asanuma, K | 1 |
| Ara, N | 1 |
| Shiroki, T | 1 |
| Kondo, Y | 1 |
| Hatta, W | 1 |
| Uno, K | 1 |
| Asano, N | 1 |
| Koike, T | 1 |
| Shimosegawa, T | 1 |
| Peles, S | 1 |
| Medda, BK | 1 |
| Zhang, Z | 1 |
| Banerjee, B | 1 |
| Lehmann, A | 1 |
| Shaker, R | 1 |
| Sengupta, JN | 1 |
| Yang, M | 1 |
| Li, ZS | 1 |
| Chen, DF | 1 |
| Zou, DW | 1 |
| Xu, XR | 1 |
| Fang, DC | 1 |
| Xu, GM | 1 |
| Stephens, RL | 1 |
| Wang, ZG | 1 |
| Li, Q | 1 |
| Kong, L | 1 |
| Zhang, S | 1 |
| Zhong, Z | 1 |
| Liu, X | 1 |
| Wang, J | 1 |
| Kang, J | 1 |
| Wells, RW | 1 |
| Morris, GP | 3 |
| Blennerhassett, MG | 1 |
| Paterson, WG | 3 |
| SIEGEL, C | 1 |
| Szentpáli, K | 1 |
| Erös, G | 1 |
| Kaszaki, J | 1 |
| Tiszlavicz, L | 1 |
| Lázár, G | 1 |
| Wolfárd, A | 1 |
| Balogh, A | 1 |
| Boros, M | 1 |
| White, RJ | 2 |
| Cooke, K | 1 |
| Tang, XD | 1 |
| Wu, HM | 1 |
| Wang, ZB | 1 |
| Shao, Y | 1 |
| Hu, YC | 1 |
| Shapiro, M | 1 |
| Green, C | 1 |
| Bautista, JM | 1 |
| Peru, RL | 1 |
| Malagon, IB | 1 |
| Corvo, M | 1 |
| Risner-Adler, S | 1 |
| Beeler, JN | 1 |
| Tuchinsky, I | 1 |
| Fass, R | 2 |
| Poplawski, C | 1 |
| Sosnowski, D | 1 |
| Szaflarska-Popławska, A | 1 |
| Sarosiek, J | 7 |
| McCallum, R | 1 |
| Bartuzi, Z | 1 |
| Richter, JE | 1 |
| Castell, DO | 4 |
| Shamsi, Z | 1 |
| Anwar, A | 1 |
| Orlando, RC | 2 |
| Powell, DW | 1 |
| Carney, CN | 1 |
| Sonnenberg, A | 1 |
| Steinkamp, U | 1 |
| Weise, A | 1 |
| Berges, W | 1 |
| Wienbeck, M | 1 |
| Rohner, HG | 1 |
| Peter, P | 1 |
| Harmon, JW | 2 |
| Johnson, LF | 2 |
| Maydonovitch, CL | 1 |
| DeRosa, J | 1 |
| Marcinkiewicz, M | 4 |
| Edmunds, M | 2 |
| McCallum, RW | 6 |
| Namiot, Z | 4 |
| Edmunds, MC | 3 |
| Rourk, RM | 2 |
| Yu, Z | 2 |
| Johnston, BT | 1 |
| Collins, JS | 1 |
| McFarland, RJ | 1 |
| Love, AH | 1 |
| Scheurich, J | 1 |
| Weiss, P | 1 |
| Yalam, JM | 1 |
| Camargo, L | 1 |
| Johnson, C | 1 |
| Garewal, HS | 1 |
| Sampliner, RE | 1 |
| Lanas, A | 1 |
| Royo, Y | 1 |
| Ortego, J | 1 |
| Molina, M | 1 |
| Sáinz, R | 1 |
| Zhang, Y | 1 |
| Irvin, TT | 1 |
| Perez-Avila, C | 1 |
| Junginger, T | 1 |
| Trost, A | 1 |
| Pichlmaier, H | 1 |
| Safaie-Shirazi, S | 1 |
| DenBesten, L | 1 |
| Zike, WL | 1 |
| Breen, KJ | 1 |
| Whelan, G | 1 |
| Sillin, LF | 1 |
| Condon, RE | 1 |
| Wilson, SD | 1 |
| Worman, LW | 1 |
| Punto, L | 1 |
| Koivisto, E | 1 |
| Marion, L | 1 |
| Sanders, B | 1 |
| Nayfield, S | 1 |
| Zfass, AM | 1 |
| Behar, J | 1 |
| Govoni, AF | 1 |
| Tobey, NA | 1 |
| Geisinger, KR | 2 |
| Cassidy, KT | 1 |
| Nardi, R | 1 |
| Tan, WC | 1 |
| Martin, RJ | 1 |
| Pandey, R | 1 |
| Ballard, RD | 1 |
| Vakil, NB | 1 |
| Kahrilas, PJ | 1 |
| Dodds, WJ | 2 |
| Vanagunas, A | 1 |
| Kiroff, GK | 1 |
| Devitt, PG | 1 |
| DeYoung, NJ | 1 |
| Jamieson, GG | 1 |
| Katz, PO | 1 |
| Hassan, M | 1 |
| Wu, WC | 1 |
| Huang, D | 1 |
| Johnson, DA | 1 |
| Winters, C | 1 |
| Spurling, TJ | 1 |
| Chobanian, SJ | 1 |
| Cattau, EL | 1 |
| Andersen, LI | 1 |
| Schmidt, A | 1 |
| Bundgaard, A | 1 |
| O'Connor, KW | 1 |
| Schweitzer, EJ | 1 |
| Bass, BL | 1 |
| Kaul, B | 2 |
| Petersen, H | 2 |
| Myrvold, HE | 2 |
| Grette, K | 2 |
| Røysland, P | 1 |
| Halvorsen, T | 2 |
| Burns, TW | 1 |
| Venturatos, SG | 1 |
| de Moraes-Filho, JP | 1 |
| Goldberg, HI | 1 |
| Gee, S | 1 |
| Montgomery, C | 1 |
| Zboralske, FF | 1 |
| Booth, DJ | 1 |
| Kemmerer, WT | 1 |
| Skinner, DB | 1 |
| Henderson, RD | 1 |
| Mugashe, F | 1 |
| Jeejeebhoy, KN | 1 |
| Cullen, J | 1 |
| Szczepanski, M | 1 |
| Boszko, A | 1 |
| Marryatt, G | 1 |
| Brant, B | 1 |
| Armstrong, RP | 1 |
| Butz, RH | 1 |
| Vetto, RM | 1 |
| Giles, GR | 1 |
| Clark, CG | 1 |
| Buchan, R | 1 |
| Bernot, R | 1 |
| Norton, RA | 1 |
| Hookman, P | 1 |
| Siegel, CI | 1 |
| Hendrix, TR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis[NCT01806220] | 24 participants (Actual) | Interventional | 2004-01-31 | Completed | |||
| Evaluation of Esophageal and Gastric Acid Levels in Patients Presenting With Upper Gastrointestinal Symptoms Using a Novel PH System[NCT00579410] | 85 participants (Actual) | Observational | 2004-05-31 | Completed | |||
| Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis: Final Results[NCT01389401] | 36 participants (Actual) | Observational | 2009-01-31 | Completed | |||
| A Clinical Study of Demographics and Findings During Endoscopy in Patients With Abdominal Pain, Dyspepsia, GERD, and Associated Symptoms[NCT00576992] | 1,177 participants (Actual) | Observational | 2003-01-31 | Terminated (stopped due to Recruitment not being met) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydrochloric acid and Esophagitis, Reflux
| Article | Year |
|---|---|
Gastroesophageal reflux. Pathogenesis, diagnosis, and therapy.
Topics: Alginates; Antacids; Barium Sulfate; Bethanechol; Bethanechol Compounds; Cimetidine; Esophagitis, Pe | 1982 |
Reflux esophagitis: pathogenesis, diagnosis, and management.
Topics: Antacids; Biopsy; Esophagitis, Peptic; Esophagogastric Junction; Esophagoscopy; Gastrins; Heartburn; | 1976 |
Gastroesophageal reflux: an update.
Topics: Collagen; Combined Modality Therapy; Drug Therapy, Combination; Esophagitis, Peptic; Esophagogastric | 1985 |
3 trials available for hydrochloric acid and Esophagitis, Reflux
| Article | Year |
|---|---|
Detrimental impact of acid and pepsin on the rate of luminal release of transforming growth factor alpha. Its potential pathogenetic role in the development of reflux esophagitis.
Topics: Adult; Basal Metabolism; Esophagitis, Peptic; Esophagus; Female; Gastric Acid; Humans; Hydrochloric | 1996 |
The De Carvalho and acid-barium tests in the demonstration of an unsuspected gastro-oesophageal reflux and its related oesophagitis.
Topics: Barium Sulfate; Clinical Trials as Topic; Esophagitis, Peptic; Gastroesophageal Reflux; Humans; Hydr | 1975 |
Pulmonary function and acid application in the esophagus.
Topics: Adult; Aged; Airway Resistance; Asthma; Atropine; Esophagitis, Peptic; Female; Humans; Hydrochloric | 1986 |
51 other studies available for hydrochloric acid and Esophagitis, Reflux
| Article | Year |
|---|---|
Estrogen Enhances Esophageal Barrier Function by Potentiating Occludin Expression.
Topics: Animals; Esophagitis, Peptic; Esophagus; Estradiol; Hydrochloric Acid; Male; Occludin; Permeability; | 2016 |
Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats.
Topics: Acrylamides; Afferent Pathways; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic | 2009 |
Quantitative assessment and characterization of visceral hyperalgesia evoked by esophageal balloon distention and acid perfusion in patients with functional heartburn, nonerosive reflux disease, and erosive esophagitis.
Topics: Acids; Adult; Analysis of Variance; Catheterization; Esophageal pH Monitoring; Esophagitis, Peptic; | 2010 |
A novel external esophageal perfusion model for reflux-associated respiratory symptoms.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Feasi | 2010 |
Effects of acid-induced esophagitis on esophageal smooth muscle.
Topics: Animals; Carbachol; Cell Separation; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Hypertrophy; | 2003 |
THE ACID PERFUSION TEST IN THE DIFFERENTIAL DIAGNOSIS OF CHEST PAIN.
Topics: Angina Pectoris; Chest Pain; Diagnosis, Differential; Esophagitis; Esophagitis, Peptic; Gastroesopha | 1965 |
Microcirculatory changes in the canine oesophageal mucosa during experimental reflux oesophagitis: comparison of the effects of acid and bile.
Topics: Acute Disease; Animals; Bile; Dogs; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Leukocytes; M | 2003 |
Morphology and glycoconjugate content of opossum esophageal epithelium and glands: regional heterogeneity and effects of acid-induced mucosal injury and recovery.
Topics: Animals; Esophagitis, Peptic; Esophagus; Glycoconjugates; Hydrochloric Acid; Hydrogen-Ion Concentrat | 2005 |
[Study on reflux esophagitis treated by Tongjiang granule].
Topics: Animals; Drug Combinations; Drugs, Chinese Herbal; Esophagitis, Peptic; Esophagus; Female; Gastric A | 2006 |
Functional heartburn patients demonstrate traits of functional bowel disorder but lack a uniform increase of chemoreceptor sensitivity to acid.
Topics: Autonomic Nervous System; Bacterial Proteins; Chemoreceptor Cells; Endoscopy, Gastrointestinal; Esop | 2006 |
Role of bile acids, prostaglandins and COX inhibitors in chronic esophagitis in a mouse model.
Topics: Animals; Bile Acids and Salts; Chronic Disease; Cyclooxygenase Inhibitors; Dinoprostone; Disease Mod | 2006 |
Intraesophageal acid perfusion test (Bernstein test).
Topics: Esophagitis, Peptic; Esophagus; Humans; Hydrochloric Acid; Intubation; Pain | 1984 |
Pathophysiology of acute acid injury in rabbit esophageal epithelium.
Topics: Animals; Biological Transport; Epithelium; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Male; | 1981 |
Salivary secretion in reflux esophagitis.
Topics: Adult; Bicarbonates; Citrates; Citric Acid; Esophagitis, Peptic; Female; Humans; Hydrochloric Acid; | 1982 |
Effects of acid and bile salts on the rabbit esophageal mucosa.
Topics: Animals; Bile Acids and Salts; Esophagitis, Peptic; Esophagus; Gastroesophageal Reflux; Hydrochloric | 1981 |
Modulatory impact of acid and pepsin on esophageal hydrophobicity in humans.
Topics: Adult; Esophagitis, Peptic; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; M | 1995 |
Declined human esophageal mucin secretion in patients with severe reflux esophagitis.
Topics: Catheterization; Esophagitis, Peptic; Esophagoscopy; Esophagus; Female; Humans; Hydrochloric Acid; M | 1994 |
Diminished luminal release of esophageal epidermal growth factor in patients with reflux esophagitis.
Topics: Epidermal Growth Factor; Esophagitis, Peptic; Esophagus; Female; Humans; Hydrochloric Acid; Male; Mi | 1994 |
Are esophageal symptoms reflux-related? A study of different scoring systems in a cohort of patients with heartburn.
Topics: Cohort Studies; Endoscopy, Digestive System; Esophagitis, Peptic; Female; Gastroesophageal Reflux; H | 1994 |
Impairment of salivary epidermal growth factor secretory response to esophageal mechanical and chemical stimulation in patients with reflux esophagitis.
Topics: Adult; Epidermal Growth Factor; Esophagitis, Peptic; Esophagus; Female; Humans; Hydrochloric Acid; H | 1994 |
Monophasic luminal release of prostaglandin E2 in patients with reflux esophagitis under the impact of acid and acid/pepsin solutions. Its potential pathogenetic significance.
Topics: Adult; Case-Control Studies; Catheterization; Dinoprostone; Esophagitis, Peptic; Esophagus; Female; | 1995 |
Increased esophageal chemoreceptor sensitivity to acid in patients after successful reversal of Barrett's esophagus.
Topics: Anti-Ulcer Agents; Barrett Esophagus; Case-Control Studies; Chemoreceptor Cells; Combined Modality T | 1997 |
Experimental esophagitis induced by acid and pepsin in rabbits mimicking human reflux esophagitis.
Topics: Acute Disease; Animals; Cell Division; Chronic Disease; Disease Models, Animal; Esophagitis, Peptic; | 1999 |
Esophagitis-related esophageal shortening in opossum is associated with longitudinal muscle hyperresponsiveness.
Topics: Animals; Deglutition; Disease Models, Animal; Epithelial Cells; Esophageal Motility Disorders; Esoph | 2001 |
Diagnosis of symptomatic gastroesophageal reflux by prolonged monitoring of lower esophageal pH.
Topics: Adult; Esophagitis, Peptic; Esophagoscopy; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydro | 1977 |
[Comparison of the value of various methods for diagnosis of gastroesophageal reflux].
Topics: Diagnosis, Differential; Esophagitis, Peptic; Esophagoscopy; Evaluation Studies as Topic; Gastroesop | 1978 |
Effect of bile salts on the ionic permeability of the esophageal mucosa and their role in the production of esophagitis.
Topics: Animals; Bile; Bile Acids and Salts; Dogs; Esophagitis; Esophagitis, Peptic; Esophagus; Gastric Juic | 1975 |
The diagnosis of reflux oesophagitis: an evaluation of five investigative procedures.
Topics: Esophagitis, Peptic; Esophagoscopy; Esophagus; Female; Humans; Hydrochloric Acid; Male; Manometry; M | 1978 |
Effective surgical therapy of esophagitis. Experience with Belsey, Hill, and Nissen operations.
Topics: Collagen Diseases; Dilatation; Endoscopy; Esophageal Achalasia; Esophageal Stenosis; Esophagitis, Pe | 1979 |
Effect of acid on the motility of the oesophagus of the pig with experimentally induced oesophagitis.
Topics: Animals; Barium Sulfate; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Mucous Membrane; Perista | 1977 |
Gastric and esophageal dysfunction after ingestion of acid.
Topics: Adult; Burns, Chemical; Deglutition Disorders; Esophagitis, Peptic; Gastric Emptying; Humans; Hydroc | 1978 |
Mechanisms of acid injury to rabbit esophageal epithelium. Role of basolateral cell membrane acidification.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Cell Membrane; Epith | 1991 |
The histologic development of acid-induced esophagitis in the cat.
Topics: Animals; Cats; Disease Models, Animal; Esophagitis, Peptic; Hydrochloric Acid; Hyperplasia; Infusion | 1990 |
Effects of spontaneous and simulated gastroesophageal reflux on sleeping asthmatics.
Topics: Adult; Airway Resistance; Asthma; Bronchial Spasm; Esophagitis, Peptic; Female; Gastroesophageal Ref | 1990 |
Absence of an upper esophageal sphincter response to acid reflux.
Topics: Adult; Esophagitis, Peptic; Esophagogastric Junction; Gastroesophageal Reflux; Humans; Hydrochloric | 1989 |
Bile salt-induced injury of rabbit oesophageal mucosa measured by hydrogen ion disappearance.
Topics: Animals; Bile Acids and Salts; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Micelles; Mucous M | 1987 |
Acid-induced esophagitis in cats is prevented by sucralfate but not synthetic prostaglandin E.
Topics: Animals; Cats; Esophagitis, Peptic; Esophagoscopy; Esophagus; Hydrochloric Acid; Hyperplasia; Indome | 1988 |
Esophageal acid sensitivity in Barrett's esophagus.
Topics: Adult; Aged; Barrett Esophagus; Esophageal Diseases; Esophagitis, Peptic; Esophagus; Humans; Hydroch | 1987 |
Sucralfate prevents experimental peptic esophagitis in rabbits.
Topics: Aluminum; Animals; Bile Acids and Salts; Esophagitis, Peptic; Esophagus; Glucose; Hydrochloric Acid; | 1985 |
Hiatus hernia in gastroesophageal reflux disease.
Topics: Barium Sulfate; Duodenoscopy; Enema; Esophagitis, Peptic; Esophagoscopy; Fiber Optic Technology; Gas | 1986 |
The acid perfusion test in gastroesophageal reflux disease.
Topics: Adult; Aged; Duodenoscopy; Esophagitis, Peptic; Esophagoscopy; Female; Fiber Optic Technology; Gastr | 1986 |
Esophageal motor function and response to acid perfusion in patients with symptomatic reflux esophagitis.
Topics: Adult; Esophagitis, Peptic; Esophagogastric Junction; Esophagus; Female; Humans; Hydrochloric Acid; | 1985 |
Editorial: Acid perfusion revisited.
Topics: Duodenal Ulcer; Esophagitis, Peptic; Gastritis; Heartburn; Humans; Hydrochloric Acid; Perfusion | 1974 |
Lack of specificity of the acid perfusion test in duodenal ulcer patients.
Topics: Adult; Duodenal Ulcer; Duodenum; Esophagitis, Peptic; Esophagoscopy; Esophagus; Evaluation Studies a | 1974 |
Role of acid and pepsin in acute experimental esophagitis.
Topics: Animals; Cats; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Hydrogen-Ion Concentration; Models | 1969 |
Acid reactivity in the distal esophagus.
Topics: Adolescent; Adult; Alkalies; Animals; Dogs; Esophagitis, Peptic; Esophagogastric Junction; Esophagus | 1970 |
The role of bile and acid in the production of esophagitis and the motor defect of esophagitis.
Topics: Animals; Bile; Bile Acids and Salts; Deglutition Disorders; Dogs; Esophagitis, Peptic; Esophagogastr | 1972 |
The diagnosis of esophagitis in surgical patients.
Topics: Adult; Aged; Esophagitis; Esophagitis, Peptic; Female; Gastrectomy; Hernia, Diaphragmatic; Humans; H | 1970 |
Effect of oesophageal perfusion with acid on basal gastric secretion.
Topics: Adult; Duodenal Ulcer; Esophagitis, Peptic; Esophagus; Gastric Juice; Gastric Mucosa; Gastroesophage | 1968 |
The esophageal acid perfusion test.
Topics: Adult; Esophagitis, Peptic; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Male; Middle | 1965 |
Failure of oxethazaine to alter acid-induced esophageal pain.
Topics: Anesthetics, Local; Catheterization; Esophagitis, Peptic; Humans; Hydrochloric Acid; Isotonic Soluti | 1966 |