Page last updated: 2024-10-17

hydrochloric acid and Esophageal Reflux

hydrochloric acid has been researched along with Esophageal Reflux in 182 studies

Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.

Research Excerpts

ExcerptRelevanceReference
"In a randomized double-blind crossover study, we perfused the esophagus with amiloride or (saline) placebo prior to eliciting acid-induced heartburn in patients with a history of proton pump inhibitor-responsive NERD."9.17Effect of amiloride on experimental acid-induced heartburn in non-erosive reflux disease. ( Bulsiewicz, WJ; Hansen, MB; Orlando, RC; Pruitt, A; Shaheen, NJ, 2013)
"The anti-tussive effect of gabapentin and its underlying neuromodulatory mechanism were investigated via a modified guinea pig model of gastroesophageal reflux-related cough (GERC)."8.31Gabapentin alleviated the cough hypersensitivity and neurogenic inflammation in a guinea pig model with repeated intra-esophageal acid perfusion. ( Chen, R; Chen, Z; Dong, J; Huang, J; Ji, X; Xu, Y; Yan, W; Zhan, C; Zheng, Z; Zhi, H; Zhong, M, 2023)
"In a randomized double-blind crossover study, we perfused the esophagus with amiloride or (saline) placebo prior to eliciting acid-induced heartburn in patients with a history of proton pump inhibitor-responsive NERD."5.17Effect of amiloride on experimental acid-induced heartburn in non-erosive reflux disease. ( Bulsiewicz, WJ; Hansen, MB; Orlando, RC; Pruitt, A; Shaheen, NJ, 2013)
"1 N hydrochloric acid (HCl) to esophageal infusion with saline in patients presenting with typical gastroesophageal reflux symptoms and erosive esophagitis."5.14Variation of the intercellular space in the esophageal epithelium in response to hydrochloridric acid infusion in patients with erosive esophagitis. ( Caldini, EG; Ferreira, MA; Hashimoto, CL; Honório, RS; Matos, RT; Navarro-Rodriguez, T, 2009)
"In this double blind study 12 subjects with asthma and gastroesophageal reflux received acid (N/10 hydrochloric acid) and antacid (mixture of magnesium trisilicate and aluminum hydroxide) perfusion in lower esophagus via a nasogastric tube."5.09Effect of intraesophageal acid instillation on airway reactivity in patients with asthma. ( Aggarwal, V; Bansal, S; Chaudhary, N; Nijhawan, S; Singh, V, 2000)
"To access the efficacy of cisapride in facilitating acid clearance in patients with symptomatic gastro-oesophageal reflux disease."5.09The role of age and salivation in acid clearance in symptomatic patients with gastro-oesophageal reflux disease. ( Chen, CL; Orr, WC; Sloan, S, 2001)
"1 N hydrochloric acid) and edrophonium (80 micrograms/kg intravenously) tests were placebo-controlled with a positive study defined as replication of typical chest pain."5.07Twenty-four-hour esophageal pH monitoring: the most useful test for evaluating noncardiac chest pain. ( Dalton, CB; Hewson, EG; Richter, JE; Sinclair, JW, 1991)
" One group of neonates at high risk for SIDS includes those who develop apnea secondary to gastroesophageal reflux (GER)."4.78Effects of acid on the larynx of the maturing rabbit and their possible significance to the sudden infant death syndrome. ( Wetmore, RF, 1993)
"The anti-tussive effect of gabapentin and its underlying neuromodulatory mechanism were investigated via a modified guinea pig model of gastroesophageal reflux-related cough (GERC)."4.31Gabapentin alleviated the cough hypersensitivity and neurogenic inflammation in a guinea pig model with repeated intra-esophageal acid perfusion. ( Chen, R; Chen, Z; Dong, J; Huang, J; Ji, X; Xu, Y; Yan, W; Zhan, C; Zheng, Z; Zhi, H; Zhong, M, 2023)
"The intensity of heartburn symptom subsequent to acid infusion was significantly reduced after capsaicin infusion as compared with saline infusion (54 ± 3 vs 61 ± 3; P = 0."3.83Effects of esophageal capsaicin instillation on acid induced excitation of secondary peristalsis in humans. ( Chen, CL; Hung, JS; Lei, WY; Liu, TT; Orr, WC; Yi, CH, 2016)
"To develop experimental models to evaluate the effects of hydrochloric acid associated with the pepsin instilled in the mucosa of the upper esophagus and the esophagogastric junction of young male rats Wistar, simulating injury caused by gastroesophageal reflux on the mucosa of aero-digestive tract in humans as well as the action of the risk exposure of mucosa to cigarette smoke."3.78Experimental model of smoking and simulation of reflux with acid and pepsin in rats. ( Altemani, AM; Andreollo, NA; Araujo, MR; Colli Neto, JA; Del Negro, A; Zen Junior, JH, 2012)
"Twelve healthy controls and 39 patients with reflux disease [14 erosive reflux disease, 11 non-erosive reflux disease with normal (functional heartburn) and 14 non-erosive reflux disease with excess acid exposure] had hydrochloric acid and saline infused into distal and then proximal oesophagus."3.74Acid-related oesophageal sensitivity, not dysmotility, differentiates subgroups of patients with non-erosive reflux disease. ( Emmanuel, AV; Kalantzis, C; Khoo, D; Thoua, NM, 2008)
"As has been demonstrated, infusion of hydrochloric acid (HCl) and pepsin into the human esophageal lumen, which mimics the natural gastroesophageal reflux, results in a significant increase in salivary volume, salivary bicarbonate and epidermal growth factor."3.69Modulatory effect of esophageal intraluminal mechanical and chemical stressors on salivary prostaglandin E2 in humans. ( Hetzel, DP; McCallum, RW; Namiot, Z; Piascik, R; Sarosiek, J; Yu, ZJ, 1997)
" It is concluded that topical TiF4 application may be effective in prevention of dental erosion caused by hydrochloric acid from the stomach in patients with frequent vomiting or gastroesophageal reflux."3.69The resistance of titanium tetrafluoride-treated human enamel to strong hydrochloric acid. ( Büyükyilmaz, T; Ogaard, B; Rølla, G, 1997)
"Upper gastrointestinal endoscopy and radiologic examination were performed in 101 patients with symptoms strongly suggestive of gastroesophageal reflux (GER) disease."3.67Hiatus hernia in gastroesophageal reflux disease. ( Grette, K; Halvorsen, T; Kaul, B; Myrvold, HE; Petersen, H; Røysland, P, 1986)
" From the study it may be concluded that not only hydrochloric acid but other components of the reflux material may be responsible for producing symptoms of gastro-oesophageal reflux."3.66Acid-sensitive oesophagus. ( Boesby, S; Madsen, T; Wallin, L, 1980)
"Heartburn is commonly associated with the presence of acid in the oesophageal lumen."2.77Oesophageal sensation in response to high PCO(2) and acidic solutions in nonerosive reflux disease. ( Akiba, Y; Ashpole, N; Fass, OZ; Fass, R; Guillén-Rodríguez, JM; Hershcovici, T; Kaunitz, JD; Poh, CH, 2012)
"Symptomatic GERD patients with erosive esophagitis (EE) or an abnormal pH test were included."2.76The effect of antireflux treatment on patients with gastroesophageal reflux disease undergoing a mental arithmetic stressor. ( Ashpole, N; Fass, R; Gasiorowska, A; Hershcovici, T; Navarro-Rodriguez, T; Noelck, N; Poh, CH; Powers, J; Wendel, CS; Willis, MR, 2011)
"Gastro-oesophageal reflux disease (GORD) is one of the most common causes of chronic cough; however, the mechanisms by which GOR initiates coughing are incompletely understood."2.73Acidification of the oesophagus acutely increases the cough sensitivity in patients with gastro-oesophageal reflux and chronic cough. ( Balaz, D; Demeter, M; Hyrdel, R; Javorkova, N; Kollarik, M; Pecova, R; Tatar, M; Varechova, S, 2008)
"Most patients with cough and gastroesophageal reflux disease (GERD) improve on medical treatment with proton pump inhibitors (PPI)."2.70Preoperative symptom evaluation and esophageal acid infusion predict response to laparoscopic Nissen fundoplication in gastroesophageal reflux patients who present with cough. ( Allen, CJ; Anvari, M, 2002)
"In seven patients with bronchial asthma (mean +/- SD age, 55."2.69Effects of esophageal acid perfusion on airway hyperresponsiveness in patients with bronchial asthma. ( Inoue, H; Kato, C; Kobayashi, H; Suzuki, K; Tanifuji, Y; Wu, DN; Yamauchi, K, 2000)
"Twenty-seven patients with GERD were categorized as group I(globus symptoms with posterior laryngitis) and group II (heartburn and/or regurgitation symptoms)."2.69Digital infrared thermographic imaging in patients with gastroesophageal reflux disease. ( Cho, YE; Lee, SI; Nah, JS; Park, HJ; Park, IS; Zhang, HY, 1998)
"Fifteen consecutive patients with systemic sclerosis and six healthy subjects underwent oesophageal manometry and an acid clearance test in three body positions (supine, recumbent at 30 degrees and seated at 90 degrees) in randomized order."2.68Oesophageal acid clearance in patients with systemic sclerosis: effect of body position. ( Barbera, R; Basilisco, G; Bianchi, P; Carola, F; Vanoli, M, 1996)
"Cough was recorded with a microphone and then computer analyzed."2.67Pathogenesis of chronic persistent cough associated with gastroesophageal reflux. ( Breslin, AB; Ing, AJ; Ngu, MC, 1994)
"Gastroesophageal reflux (GER) has been shown to be more frequent in people with asthma, but the mechanism by which it might aggravate asthmatic symptoms remains unclear."2.66Intraesophageal perfusion of acid increases the bronchomotor response to methacholine and to isocapnic hyperventilation in asthmatic subjects. ( Denjean, A; Duroux, P; Herve, P; Jian, R; Simonneau, G, 1986)
"The presence of gastro-oesophageal reflux was investigated in 18 children with moderate to severe asthma by overnight oesophageal pH monitoring."2.66Gastro-oesophageal reflux and childhood asthma: the acid test. ( Charette, L; Silverman, M; Thomson, AH; Wilson, NM, 1985)
"The diagnosis of GERD requires the thoughtful evaluation of a patient's symptoms and clinical course."2.38Detection and treatment of gastroesophageal reflux disease. ( Fisher, RS; Ogorek, CP, 1989)
"GERDQ was negatively correlated to lag time (r = -."1.51Esophageal acid sensitivity in patients with gastroesophageal reflux disease: Does esophageal hypomotility matter? ( Chen, CL; Hung, JS; Lei, WY; Liu, TT; Wong, MW; Yi, CH, 2019)
"Potential conditions of gastroesophageal reflux were simulated, via infusion of 0."1.48Older Age Reduces Upper Esophageal Sphincter and Esophageal Body Responses to Simulated Slow and Ultraslow Reflux Events and Post-Reflux Residue. ( Dua, A; Dua, K; Edeani, F; Gao, S; Kern, M; Lynch, S; Mei, L; Sanvanson, P; Shaker, R; Wilson, A, 2018)
"Gastroesophageal reflux disease (GERD) clinically predisposes to columnar Barrett's metaplasia (BM) in the distal esophagus."1.46Barrett's metaplasia develops from cellular reprograming of esophageal squamous epithelium due to gastroesophageal reflux. ( Bajpai, M; Cheng, CL; Chouthai, AA; Das, KM; Geng, X; Minacapelli, CD; Souza, R; Spechler, SJ, 2017)
"Patients with Barrett's esophagus exhibited acid hypersensitivity but hyposensitivity to other stimuli."1.46Patients with Barrett's esophagus are hypersensitive to acid but hyposensitive to other stimuli compared with healthy controls. ( Drewes, AM; Ejstrud, P; Gregersen, H; Krarup, AL; Lottrup, C, 2017)
"Differences in FC between GERD patients and healthy subjects were determined across the 4 study conditions."1.42Esophageal acid stimulation alters insular cortex functional connectivity in gastroesophageal reflux disease. ( Babaei, A; Kern, M; Li, SJ; Samuel, EA; Shaker, R; Siwiec, RM, 2015)
"Gastroesophageal reflux is a common disorder closely related to chronic airway diseases, such as chronic cough, asthma, chronic bronchitis, and chronic obstructive disease."1.40Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs. ( Cao, AL; Cheng, YM; Liu, CF; Sun, YS; Wang, HW; Wang, Y; Wu, DZ; Zhang, BB; Zheng, JP; Zhu, SL, 2014)
"The pathogenesis of gastroesophageal reflux disease (GERD) remains elusive, but recent evidence suggests that early secretion of inflammatory cytokines and chemokines by the mucosa leads to influx of immune cells followed by tissue damage."1.38HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells. ( Altomare, A; Behar, J; Biancani, P; Cao, W; Cicala, M; Fiocchi, C; Guarino, M; Harnett, KM; Li, D; Ma, J; Rieder, F, 2012)
"Patients with GERD and a control group of healthy asymptomatic volunteers were recruited."1.37Non-erosive reflux disease (NERD), symptomatic and asymptomatic erosive reflux disease (ERD): from hypersensitive to hyposensitive esophagus. ( Goh, KL; Hartono, JL; Qua, CS, 2011)
"The pathogenesis of gastro-oesophageal reflux disease includes increased acid reflux, reduced salivation and impaired peristalsis."1.36Modulation of salivation and heartburn in response to the site of acid infusion in the human oesophagus. ( Agrawal, K; Dutta, SK; Mahmoud, MA, 2010)
"Gastro-oesophageal reflux is frequent in chronic airway diseases and is considered a trigger for symptoms."1.36Tiotropium reduction of lung inflammation in a model of chronic gastro-oesophageal reflux. ( Advenier, C; Chen, H; Cui, Y; Devillier, P; Kuang, X; Wang, H; Xia, Z; Xu, Z; Zemoura, L; Zhu, L, 2010)
"Gastroesophageal reflux disease (GERD) has been linked to a number of extra-esophageal symptoms and disorders, primarily in the respiratory tract."1.36A novel external esophageal perfusion model for reflux-associated respiratory symptoms. ( Kang, J; Kong, L; Li, Q; Liu, X; Wang, J; Zhang, S; Zhong, Z, 2010)
"Eosinophilic esophagitis mimics GERD, but eosinophil granule proteins, known to mediate inflammation, have not been linked to BE."1.36Inflammatory mediators of esophagitis alter p27 Kip1 expression in esophageal epithelial cells. ( Blain, SW; Gress, F; Nguyen, KD; Treem, WR, 2010)
"Distal esophageal acidification induces hyperalgesia in the non-acid exposed proximal esophagus, due to the sensitization of spinal dorsal horn neurones."1.36Anxiety increases acid-induced esophageal hyperalgesia. ( Aziz, Q; Gregory, L; Paine, P; Sharma, A; Van Oudenhove, L, 2010)
"The investigation of duodena gastro esophageal reflux (DGER) implies both clinical and experimental studies."1.35Experimental study on the effect of bile, and bile and hydrochloric acid mixture on the esophageal mucosa. ( Căruntu, ID; Lupuşoru, C; Manea, GS, 2009)
"During endoscopy in patients with GERD with and without Barrett's esophagus, we took biopsy specimens from the distal squamous esophagus to study MAPK proteins before and after esophageal perfusion with 0."1.35Differences in activity and phosphorylation of MAPK enzymes in esophageal squamous cells of GERD patients with and without Barrett's esophagus. ( Chen, X; Elder, F; Hormi-Carver, K; Souza, RF; Spechler, SJ; Thomas, D; Zhang, HY; Zhang, X, 2008)
"Gastroesophageal reflux is related to various laryngeal manifestations."1.33Effect of acid and pepsin on glottic wound healing: a simulated reflux model. ( Roh, JL; Yoon, YH, 2006)
"It has been suggested that gastro-oesophageal reflux disease (GORD) may also impair LPS, although the underlying mechanism is unclear."1.33Patients with gastro-oesophageal reflux disease and cough have impaired laryngopharyngeal mechanosensitivity. ( Ing, AJ; McGarvey, LP; Ngu, MC; Phua, SY, 2005)
"Naloxone pretreatment abolished the effect of morphine, but was enable to block the inhibitory effect of nociceptin."1.32Nociceptin inhibits airway microvascular leakage induced by HCl intra-oesophageal instillation. ( Advenier, C; Bardou, M; Cui, YY; D'Agostino, B; Faisy, C; Naline, E; Rouget, C, 2004)
"A total of 12 GERD patients (six male, six female; mean age 37."1.32Autonomic responses to heartburn induced by esophageal acid infusion. ( Chen, CL; Orr, WC, 2004)
"Proximal acid migration resulting from gastroesophageal reflux has been implicated in aerodigestive complaints and disorders."1.31Proximal migration of esophageal acid perfusions during waking and sleep. ( Elsenbruch, S; Harnish, MJ; Johnson, LF; Orr, WC, 2000)
"older patients with gastro-oesophageal reflux disease have reduced symptom severity for heartburn despite a tendency towards increased severity of oesophageal mucosal injury and acid exposure."1.31Symptom severity and oesophageal chemosensitivity to acid in older and young patients with gastro-oesophageal reflux. ( Fass, R; Garewal, HS; Johnson, C; Pulliam, G; Sampliner, RE, 2000)
"This phenomenon in patients with E (-) GERD may, by enhancing the quantity of the esophageal pre-epithelial barrier, help to prevent the development of erosive esophagitis."1.31The potential role of the esophageal pre-epithelial barrier components in the maintenance of integrity of the esophageal mucosa in patients with endoscopically negative gastroesophageal reflux disease. ( Goldin, G; Gramley, W; Han, K; Marcinkiewicz, M; Poplawski, C; Sarosiek, J; Zbroch, T, 2000)
"Gastro-oesophageal reflux is a common clinical disorder associated with a variety of respiratory symptoms, including chronic cough and exacerbation of asthma."1.31Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation. ( Advenier, C; Alt, XE; D'Agostino, B; Daoui, S; Gallelli, L; Rossi, F, 2002)
"Cartilage necrosis was prominent in all groups, and airway sizes and cross-sectional areas of the grafts were not significantly different among the 3 groups."1.31Simulated reflux and laryngotracheal reconstruction: a rabbit model. ( Carron, JD; Derkay, CS; Greinwald, JH; Oberman, JP; Werner, AL, 2001)
"Gastro-oesophageal reflux was simulated by the injection of boluses of 0."1.31Airway protection following simulated gastro-oesophageal reflux in sedated and sleeping neonatal piglets during active sleep. ( Jeffery, HE; McKelvey, GM; Post, EJ; Wood, AK, 2001)
"Gastroesophageal reflux may induce ET dysfunction."1.31Function of the eustachian tube after weekly exposure to pepsin/hydrochloric acid. ( Hardy, SM; Heavner, SB; McQueen, CT; Pillsbury, HC; Prazma, J; White, DR, 2001)
"Patients with gastro-oesophageal reflux disease (GORD) frequently report that meals high in fat worsen heartburn."1.31Duodenal fat intensifies the perception of heartburn. ( Elashoff, JD; Fass, R; Lembo, A; Mayer, EA; Meyer, JH, 2001)
"Gastroesophageal reflux is a common problem in the newborn and preschool periods."1.31Transient inflammation and dysfunction of the eustachian tube secondary to multiple exposures of simulated gastroesophageal refluxant. ( Hardy, SM; Heavner, SB; Pillsbury, HC; Prazma, J; White, DR, 2001)
"The relationship of the pH of oesophageal refluxate and its pepsin content to injury of oesophageal mucosa remains unclear."1.30Experimental study of acid burden and acute oesophagitis. ( Castell, DO; Geisinger, KR; Katzka, DA; Mohiuddin, MA; Pursnani, KG; Weinbaum, G, 1998)
"Gastroesophageal reflux (GER) has been shown, clinically and experimentally, to cause inflammation of traumatized laryngeal mucosa."1.30Effects of simulated gastroesophageal reflux on the untraumatized rabbit larynx. ( al-Jubab, A; Bernard, C; Davis, M; Ludemann, JP; Manoukian, J; Shaw, K, 1998)
"The relationship between gastroesophageal reflux (GER) and asthma remains controversial."1.30The effects of acid perfusion of the esophagus on ventilation and respiratory sensation. ( Evans, JA; Field, SK; Price, LM, 1998)
"Gastroesophageal reflux has been indicated as an etiopathological factor in disorders of the upper airway."1.30Effects of HCl-pepsin laryngeal instillations on upper airway patency-maintaining mechanisms. ( Chung, K; Sant'Ambrogio, FB; Sant'Ambrogio, G, 1998)
"Reflux esophagitis and hiatal hernia commonly coexist, yet a cause and effect relationship remains unclear."1.29Esophageal shortening induced by short-term intraluminal acid perfusion in opossum: a cause for hiatus hernia? ( Kolyn, DM; Paterson, WG, 1994)
"To study mechanisms of gastroesophageal reflux-induced bronchoconstriction during intraesophageal infusions."1.29Gastroesophageal reflux-induced bronchoconstriction. An intraesophageal acid infusion study using state-of-the-art technology. ( Bradley, LA; Haile, JM; Harding, SM; Richter, JE; Schan, CA, 1994)
"The cough was induced by the insertion of nylon fibre into the airways and its intensity was evaluated from the changes in oesophageal pressure."1.29[The effect of experimental gastroesophageal reflux on the cough reflex in anesthetized cats]. ( Pécová, R; Tatár, M, 1996)
"The relationship between gastroesophageal reflux disease and these symptoms has been studied but remains unclear."1.29Role of gastroesophageal reflux disease in patients with cervical symptoms. ( Freeman, J; Goldberg, M; Mendelsohn, M; Rival, R; Rosgen, S; Wong, R, 1995)
"Gastroesophageal Reflux (GER) in children manifests itself by several clinical pictures."1.28[Acidic stimulation of esophageal peristalsis: its prognostic value in reflux]. ( Arana, J; Tapia, I; Tovar, JA, 1990)
"We conclude that gastroesophageal reflux contributes little to the nocturnal worsening of asthma."1.28Effects of spontaneous and simulated gastroesophageal reflux on sleeping asthmatics. ( Ballard, RD; Martin, RJ; Pandey, R; Tan, WC, 1990)
"Although coronary artery disease and gastroesophageal reflux disease are common conditions which, therefore, may coexist, it is unknown whether or not the presence of one affects the other."1.27Esophageal acid perfusion in coronary artery disease. Induction of myocardial ischemia. ( Haye, OL; Mellow, MH; Schoolmeester, L; Simpson, AG; Watt, L, 1983)
"Ischaemic heart disease and gastro-oesophageal reflux are both common, and the possibility that acid reflux may aggravate angina should be borne in mind, particularly when oesophageal symptoms are present."1.27Oesophageal stimulation lowers exertional angina threshold. ( Brown, AL; Davies, HA; Lewis, MJ; Page, Z; Petch, MC; Rush, EM, 1985)
"Five patients with bronchial asthma but without symptoms of gastro-oesophageal reflux (group 2) and five patients with symptoms of gastro-oesophageal reflux but without respiratory symptoms (group 3) served as controls."1.26Bronchial obstruction after oesophageal acid perfusion in asthmatics. ( Kjellén, G; Tibbling, L; Wranne, B, 1981)
"the pain has been analyzed to determine its characteristic and its atypical features."1.26Characteristics of esophageal pain. ( Henderson, RD; Marryatt, G, 1981)
"Clinically, a gastro-esophageal reflux was found in 72% of the cases."1.26[Comparison of the value of various methods for diagnosis of gastroesophageal reflux]. ( Junginger, T; Pichlmaier, H; Trost, A, 1978)

Research

Studies (182)

TimeframeStudies, this research(%)All Research%
pre-199076 (41.76)18.7374
1990's32 (17.58)18.2507
2000's44 (24.18)29.6817
2010's29 (15.93)24.3611
2020's1 (0.55)2.80

Authors

AuthorsStudies
Zhi, H1
Zhong, M1
Huang, J1
Zheng, Z1
Ji, X1
Xu, Y1
Dong, J1
Yan, W1
Chen, Z1
Zhan, C1
Chen, R1
Wong, MW1
Hung, JS2
Lei, WY2
Liu, TT4
Yi, CH4
Chen, CL6
Minacapelli, CD1
Bajpai, M1
Geng, X1
Cheng, CL1
Chouthai, AA1
Souza, R1
Spechler, SJ2
Das, KM1
Mei, L2
Dua, A1
Kern, M3
Gao, S1
Edeani, F1
Dua, K1
Wilson, A1
Lynch, S1
Sanvanson, P1
Shaker, R5
Xu, Z2
Liao, B1
Zhang, R1
Li, Y1
Wang, L1
Jia, BY1
Xie, CE1
Wang, ZB1
Pei, WJ1
Li, XH1
Shi, L1
Liu, JL1
Han, YF1
Tan, X1
Ding, PH1
Sun, ZM1
Yuan, WJ1
Li, JX1
Bulsiewicz, WJ1
Shaheen, NJ1
Hansen, MB2
Pruitt, A1
Orlando, RC3
Forcelini, CM1
Tomiozzo, JC1
Farré, R1
Van Oudenhove, L2
Callegari-Jacques, SM1
Ribeiro, M1
Madalosso, BH1
Fornari, F1
Cheng, YM1
Cao, AL1
Zheng, JP1
Wang, HW1
Sun, YS1
Liu, CF1
Zhang, BB1
Wang, Y1
Zhu, SL1
Wu, DZ1
Felder, M1
Stucki, AO1
Stucki, JD1
Geiser, T1
Guenat, OT1
Siwiec, RM1
Babaei, A1
Samuel, EA1
Li, SJ1
Orr, WC6
van Hoeij, FB1
Weijenborg, PW1
van den Bergh Weerman, MA1
van den Wijngaard, RM1
Verheij, J1
Smout, AJ1
Bredenoord, AJ1
Lottrup, C1
Krarup, AL2
Gregersen, H1
Ejstrud, P1
Drewes, AM2
Tobey, NA2
Gambling, TM1
Vanegas, XC1
Carson, JL1
Zhang, HY2
Zhang, X1
Chen, X1
Thomas, D1
Hormi-Carver, K1
Elder, F1
Souza, RF1
Banerjee, B1
Medda, BK2
Zheng, Y1
Miller, H1
Miranda, A1
Sengupta, JN1
Manea, GS1
Lupuşoru, C1
Căruntu, ID1
Matos, RT1
Honório, RS1
Caldini, EG1
Hashimoto, CL1
Ferreira, MA1
Navarro-Rodriguez, T2
Cui, Y1
Devillier, P1
Kuang, X1
Wang, H1
Zhu, L2
Xia, Z1
Zemoura, L1
Advenier, C5
Chen, H1
Li, QZ1
Kong, LF1
Zhang, SN1
Zhong, ZS1
Zhang, BH1
Liu, XF1
Xu, S1
Zheng, F1
Zhao, X1
Chen, Y1
Kong, X1
Wang, C1
Wang, Z1
Hartono, JL1
Qua, CS1
Goh, KL1
Li, Q1
Kong, L1
Zhang, S1
Zhong, Z1
Liu, X1
Wang, J1
Kang, J1
Erickson, E1
Sivasankar, M1
Dutta, SK1
Agrawal, K1
Mahmoud, MA1
Nguyen, KD1
Blain, SW1
Gress, F1
Treem, WR1
Sharma, A1
Paine, P1
Gregory, L1
Aziz, Q2
Simrén, M1
Funch-Jensen, P1
Hvid-Jensen, F1
Brun, J1
Ohmure, H1
Oikawa, K1
Kanematsu, K1
Saito, Y1
Yamamoto, T1
Nagahama, H1
Tsubouchi, H1
Miyawaki, S1
Poh, CH2
Hershcovici, T2
Gasiorowska, A1
Willis, MR1
Powers, J1
Ashpole, N2
Wendel, CS1
Noelck, N1
Fass, R5
Fass, OZ1
Akiba, Y1
Guillén-Rodríguez, JM1
Kaunitz, JD1
Zen Junior, JH1
Del Negro, A1
Colli Neto, JA1
Araujo, MR1
Altemani, AM1
Andreollo, NA1
Szczesniak, MM1
Fuentealba, SE1
Cook, IJ1
Ma, J1
Altomare, A1
Guarino, M1
Cicala, M1
Rieder, F1
Fiocchi, C1
Li, D1
Cao, W1
Behar, J1
Biancani, P1
Harnett, KM1
Allen, CJ1
Anvari, M1
Daoui, S1
D'Agostino, B4
Gallelli, L2
Alt, XE1
Rossi, F3
Vantrappen, G1
Tack, J1
Huyberechts, G1
Sifrim, D1
Geboes, K1
Janmsens, J1
Van Overstraeten, R1
Casselbrant, A2
Pettersson, A1
Fändriks, L1
Fletcher, J1
Gillen, D1
Wirz, A1
McColl, KE1
Suwanprathes, P1
Ngu, M1
Ing, A1
Hunt, G1
Seow, F1
SIEGEL, C1
Rouget, C1
Cui, YY2
Faisy, C1
Naline, E2
Bardou, M1
Marrocco, G2
De Nardo, M1
Calò, G1
Guerrini, R1
Bove, M2
Vieth, M2
Ny, L2
Lundell, L2
Ruth, M2
Phua, SY1
McGarvey, LP1
Ngu, MC2
Ing, AJ2
Dombrowski, F1
Shapiro, M1
Green, C1
Bautista, JM1
Peru, RL1
Malagon, IB1
Corvo, M1
Risner-Adler, S1
Beeler, JN1
Tuchinsky, I1
Rodriguez-Stanley, S1
Bemben, D1
Zubaidi, S1
Redinger, N1
Miner, PB1
Roh, JL1
Yoon, YH1
Konda, Y1
Risse, PA1
Zhang, Y1
Chen, HZ1
Finance, O1
Rinaldi-Carmona, M1
Lang, IM1
Haworth, ST1
Roerig, DL1
Forster, HV1
Javorkova, N1
Varechova, S1
Pecova, R2
Tatar, M2
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Kollarik, M1
Thoua, NM1
Khoo, D1
Kalantzis, C1
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Samson, N1
Duvareille, C1
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Hove, LH1
Holme, B1
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Lawal, A1
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Mepani, R1
Rittmann, T1
Hussaini, S1
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Tatro, L1
Jesmanowicz, A1
Verber, M1
Matthews, PJ1
Knowles, CH1
Chua, YC1
Delaney, C1
Hobson, AR1
Richter, JE7
Castell, DO4
Tuchman, DN1
Boyle, JT1
Pack, AI1
Scwartz, J1
Kokonos, M1
Spitzer, AR1
Cohen, S2
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Larsen, GL1
Grunstein, MM1
Kjellén, G4
Svedberg, JB1
Mellow, MH1
Simpson, AG1
Watt, L1
Schoolmeester, L1
Haye, OL1
Henderson, RD3
Marryatt, G3
Bright-Asare, P1
El-Bassoussi, M1
Winnan, GR1
Meyer, CT1
McCallum, RW5
Malmud, LS1
Fisher, RS2
Joelsson, BE1
DeMeester, TR2
Skinner, DB4
LaFontaine, E1
Waters, PF1
O'Sullivan, GC1
Madsen, T2
Wallin, L2
Boesby, S4
Larsen, VH1
Tibbling, L4
Wranne, B1
Ahtaridis, G1
Snape, WJ1
Silverstein, BD1
Pope, CE1
Harmon, JW1
Johnson, LF2
Maydonovitch, CL1
DeRosa, J1
Marcinkiewicz, M2
Sarosiek, J5
Edmunds, M1
Rival, R1
Wong, R1
Mendelsohn, M1
Rosgen, S1
Goldberg, M1
Freeman, J1
Ganatra, JV1
Medow, MS1
Berezin, S1
Newman, LJ1
Glassman, M1
Bostwick, HE1
Halata, M1
Schwarz, SM1
Paterson, WG2
Kolyn, DM1
Schan, CA1
Harding, SM1
Haile, JM1
Bradley, LA1
Breslin, AB1
Johnston, BT1
Collins, JS1
McFarland, RJ1
Love, AH1
Namiot, Z3
Rourk, RM2
Piascik, R2
Hetzel, DP3
Yu, Z1
Wetmore, RF1
Basilisco, G1
Carola, F1
Vanoli, M1
Bianchi, P1
Barbera, R1
Chauhan, A1
Petch, MC2
Schofield, PM1
Yu, ZJ1
von Schönfeld, J1
Hector, M1
Evans, DF1
Wingate, DL1
Büyükyilmaz, T1
Ogaard, B1
Rølla, G1
Sant'Ambrogio, FB1
Sant'Ambrogio, G1
Chung, K1
Field, SK1
Evans, JA1
Price, LM1
Pursnani, KG1
Mohiuddin, MA1
Geisinger, KR1
Weinbaum, G1
Katzka, DA1
Ludemann, JP1
Manoukian, J1
Shaw, K1
Bernard, C1
Davis, M1
al-Jubab, A1
Park, HJ1
Nah, JS1
Cho, YE1
Lee, SI1
Park, IS1
Jones, MP1
Schubert, ML1
Fiasse, R1
Elsenbruch, S1
Harnish, MJ1
Adams, J1
Heintz, P1
Gross, N1
Andersen, P1
Everts, E1
Wax, M1
Cohen, J1
Pulliam, G1
Johnson, C1
Garewal, HS1
Sampliner, RE1
Han, K1
Zbroch, T1
Poplawski, C1
Gramley, W1
Goldin, G1
Wu, DN1
Tanifuji, Y1
Kobayashi, H1
Yamauchi, K1
Kato, C1
Suzuki, K1
Inoue, H1
Singh, V1
Aggarwal, V1
Bansal, S1
Nijhawan, S1
Chaudhary, N1
Carron, JD1
Greinwald, JH1
Oberman, JP1
Werner, AL1
Derkay, CS1
McKelvey, GM1
Post, EJ1
Wood, AK1
Jeffery, HE1
Sloan, S1
Heavner, SB2
Hardy, SM2
White, DR2
McQueen, CT1
Prazma, J2
Pillsbury, HC2
Meyer, JH1
Lembo, A1
Elashoff, JD1
Mayer, EA1
Mangano, M1
Colombo, P1
Bianchi, PA1
Penagini, R1
Irvin, TT1
Perez-Avila, C1
Blumhagen, JD1
Christie, DL2
Junginger, T1
Trost, A1
Pichlmaier, H1
Safaie-Shirazi, S1
DenBesten, L1
Zike, WL1
Maher, JW1
Crandall, V1
Woodward, ER1
Govoni, AF1
Sladen, GE1
Riddell, RH1
Willoughby, JM1
Dilawari, JB1
Blendis, LM1
Edwards, DA1
Krejs, GJ2
Lobsiger, MM1
Rau, R1
Bron, BA2
von Büren, US1
Peter, P1
Brändli, HH2
Pirozynski, W1
Blum, AL2
Seefeld, U1
Caro, G1
Schmid, P1
Rokkas, T1
Anggiansah, A1
McCullagh, M1
Owen, WJ1
Howard, PJ1
Maher, L1
Pryde, A1
Heading, RC1
Hewson, EG3
Sinclair, JW3
Dalton, CB3
Arana, J1
Tapia, I1
Tovar, JA1
Wright, RA1
Miller, SA1
Corsello, BF1
Tan, WC1
Martin, RJ1
Pandey, R1
Ballard, RD1
Ogorek, CP1
Wu, WC2
Powell, DW1
Schreiner, VJ1
Vakil, NB1
Kahrilas, PJ1
Dodds, WJ1
Vanagunas, A1
Ekström, T1
Davies, HA1
Page, Z1
Rush, EM1
Brown, AL1
Lewis, MJ1
Herve, P1
Denjean, A1
Jian, R1
Simonneau, G1
Duroux, P1
Ducolone, A2
Vandevenne, A2
Jouin, H2
Grob, JC2
Coumaros, D2
Meyer, C2
Burghard, G2
Methlin, G2
Hollender, L2
Fuchs, KH1
Albertucci, M1
McLean, TR2
Bombeck, CT3
Nyhus, LM3
O'Connor, KW1
Hollwarth, ME1
Smith, M1
Kvietys, PR1
Granger, DN1
Fransson, SG1
Lindström, F1
Sökjer, H1
Kaul, B2
Petersen, H2
Myrvold, HE2
Grette, K2
Røysland, P1
Halvorsen, T2
Johns, DN1
Wilson, NM1
Charette, L1
Thomson, AH1
Silverman, M1
Bennett, JR3
Atkinson, M2
Pätzold, K1
Rösch, W1
Mugashe, FL1
Jeejeebhoy, KN2
Szczpanski, MM1
Cullen, J2
Boszko, A2
Battle, WS1
Zühlke, V1
Siewert, R1
Burkhardt, K1
Becker, HD1
Peiper, HJ1
McCall, IW1
Davies, ER1
Delahunty, JE2
de Moraes-Filho, JP1
Stanciu, C1
Booth, DJ3
Kemmerer, WT2
Spencer, J1
Crozier, RE1
Gregg, JA1
Garabedian, MM1
Mugashe, F1
Szczepanski, M1
De la Revilla, L1
Martin-Vivaldi, R1
Ventin, JL1
Hernandez, L1
Thomas, CJ1
Affolter, H1
Giles, GR2
Humphries, C1
Mason, MC1
Clark, CG2
Keel, HJ1
Blättler, W1
Ardran, GM1
Rudolph, I1
Herrera, AF1
Stein, GN1
Roth, JL1
Garabedian, M1
Buchan, R1
Bernot, R1
Norton, RA1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Upper Esophageal Sphincter Pressure Variation During Anesthesia Induction[NCT04413422]20 participants (Actual)Observational2017-01-10Completed
Study of a Dietary Supplement for Reflux During Sleep[NCT02274636]50 participants (Anticipated)Interventional2014-10-31Not yet recruiting
Evaluation of Esophageal and Gastric Acid Levels in Patients Presenting With Upper Gastrointestinal Symptoms Using a Novel PH System[NCT00579410]85 participants (Actual)Observational2004-05-31Completed
A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265]Phase 418 participants (Actual)Interventional2006-08-31Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.)
Role of Empiric Anti-reflux Therapy in Pediatric Otitis Media With Effusion - a Pilot Study[NCT01082029]Phase 465 participants (Actual)Interventional2010-03-31Completed
The Study of the Diagnosis of Eustachian Tube Dysfunction (ETD): Identifying the Relationship of Ear Fullness to Laryngopharyngeal Reflux (LPR)[NCT02123498]Phase 40 participants (Actual)InterventionalWithdrawn (stopped due to IRB not approved)
A Clinical Study of Demographics and Findings During Endoscopy in Patients With Abdominal Pain, Dyspepsia, GERD, and Associated Symptoms[NCT00576992]1,177 participants (Actual)Observational2003-01-31Terminated (stopped due to Recruitment not being met)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for hydrochloric acid and Esophageal Reflux

ArticleYear
[Bernstein test].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:5

    Topics: Chest Pain; Diagnostic Techniques, Digestive System; Esophagoscopy; Esophagus; Gastroesophageal Refl

2007
Gastroesophageal reflux. Pathogenesis, diagnosis, and therapy.
    Annals of internal medicine, 1982, Volume: 97, Issue:1

    Topics: Alginates; Antacids; Barium Sulfate; Bethanechol; Bethanechol Compounds; Cimetidine; Esophagitis, Pe

1982
Effects of acid on the larynx of the maturing rabbit and their possible significance to the sudden infant death syndrome.
    The Laryngoscope, 1993, Volume: 103, Issue:11 Pt 1

    Topics: Aging; Airway Obstruction; Animals; Apnea; Female; Gastroesophageal Reflux; Humans; Hydrochloric Aci

1993
Gastroesophageal reflux: diagnosis and management.
    Hospital practice (Office ed.), 1992, Jan-15, Volume: 27, Issue:1

    Topics: Alginates; Antacids; Barium; Bethanechol Compounds; Cisapride; Endoscopy, Gastrointestinal; Gastric

1992
Detection and treatment of gastroesophageal reflux disease.
    Gastroenterology clinics of North America, 1989, Volume: 18, Issue:2

    Topics: Endoscopy; Esophagus; Gastric Mucosa; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hydrogen-I

1989
Gastroesophageal reflux: an update.
    Indiana medicine : the journal of the Indiana State Medical Association, 1985, Volume: 78, Issue:3

    Topics: Collagen; Combined Modality Therapy; Drug Therapy, Combination; Esophagitis, Peptic; Esophagogastric

1985

Trials

29 trials available for hydrochloric acid and Esophageal Reflux

ArticleYear
Effect of amiloride on experimental acid-induced heartburn in non-erosive reflux disease.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:7

    Topics: Acid Sensing Ion Channel Blockers; Administration, Topical; Adolescent; Adult; Aged; Amiloride; Cros

2013
Effect of nortriptyline on brain responses to painful esophageal acid infusion in patients with non-erosive reflux disease.
    Neurogastroenterology and motility, 2014, Volume: 26, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Brain; Brain Mapping; Cross-Over Studies; Double-Blind Meth

2014
Variation of the intercellular space in the esophageal epithelium in response to hydrochloridric acid infusion in patients with erosive esophagitis.
    Clinics (Sao Paulo, Brazil), 2009, Volume: 64, Issue:7

    Topics: Adolescent; Adult; Aged; Biopsy; Epithelium; Esophagitis; Esophagus; Extracellular Space; Female; Ga

2009
Influence of experimental esophageal acidification on sleep bruxism: a randomized trial.
    Journal of dental research, 2011, Volume: 90, Issue:5

    Topics: Administration, Topical; Adult; Arousal; Cross-Over Studies; Deglutition; Electromyography; Esophage

2011
The effect of antireflux treatment on patients with gastroesophageal reflux disease undergoing a mental arithmetic stressor.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:11

    Topics: Anti-Ulcer Agents; Esomeprazole; Esophageal pH Monitoring; Esophagus; Gastroesophageal Reflux; Human

2011
Oesophageal sensation in response to high PCO(2) and acidic solutions in nonerosive reflux disease.
    European journal of clinical investigation, 2012, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbon Dioxide; Case-Control Studies; Cross-Over Studies

2012
Acid sensitization of esophageal mucosal afferents: implication for symptom perception in patients across the gastroesophageal reflux disease spectrum.
    The Clinical journal of pain, 2013, Volume: 29, Issue:1

    Topics: Adult; Afferent Pathways; Aged; Esophagus; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydro

2013
Preoperative symptom evaluation and esophageal acid infusion predict response to laparoscopic Nissen fundoplication in gastroesophageal reflux patients who present with cough.
    Surgical endoscopy, 2002, Volume: 16, Issue:7

    Topics: Cough; Double-Blind Method; Esophagus; Female; Follow-Up Studies; Fundoplication; Gastroesophageal R

2002
Barrett's esophagus evokes a quantitatively and qualitatively altered response to both acid and hypertonic solutions.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:7

    Topics: Adult; Aged; Barrett Esophagus; Double-Blind Method; Esophagus; Gastroesophageal Reflux; Humans; Hyd

2003
Acid challenge to the esophageal mucosa: effects on local nitric oxide formation and its relation to epithelial functions.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:4

    Topics: Adult; Aged; Blotting, Western; Electrophysiology; Esophagus; Female; Gastroesophageal Reflux; Human

2005
Acid challenge to the human esophageal mucosa: effects on epithelial architecture in health and disease.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:8

    Topics: Adult; Aged; Drug Administration Schedule; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydro

2005
Effect of esophageal acid and prophylactic rabeprazole on performance in runners.
    Medicine and science in sports and exercise, 2006, Volume: 38, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Esophagus; Exercise Test; Female;

2006
Acidification of the oesophagus acutely increases the cough sensitivity in patients with gastro-oesophageal reflux and chronic cough.
    Neurogastroenterology and motility, 2008, Volume: 20, Issue:2

    Topics: Acids; Adult; Chronic Disease; Cough; Double-Blind Method; Esophagus; Female; Gastroesophageal Reflu

2008
Effects of the concentration and frequency of acid infusion on the development and maintenance of esophageal hyperalgesia in a human volunteer model.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:4

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electric

2008
Respiratory response to intraesophageal acid infusion in asthmatic children during sleep.
    The Journal of allergy and clinical immunology, 1983, Volume: 72, Issue:4

    Topics: Adolescent; Asthma; Bronchial Spasm; Child; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydr

1983
Cimetidine, metoclopramide, or placebo in the treatment of symptomatic gastroesophageal reflux.
    Journal of clinical gastroenterology, 1980, Volume: 2, Issue:2

    Topics: Adult; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Gastroesophageal Reflux; G

1980
Interpretation of the Bernstein test: a reappraisal of criteria.
    Annals of internal medicine, 1982, Volume: 96, Issue:3

    Topics: Adult; Antacids; Evaluation Studies as Topic; Gastroesophageal Reflux; Heartburn; Humans; Hydrochlor

1982
Pathogenesis of chronic persistent cough associated with gastroesophageal reflux.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Adult; Afferent Pathways; Chronic Disease; Cough; Double-Blind Method; Efferent Pathways; Esophagus;

1994
Oesophageal acid clearance in patients with systemic sclerosis: effect of body position.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Deglutition; Deglutition Disorders; Esophageal Motility Disorders; Esophagi

1996
Digital infrared thermographic imaging in patients with gastroesophageal reflux disease.
    Journal of Korean medical science, 1998, Volume: 13, Issue:3

    Topics: Adult; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Image Processing, Computer-Assist

1998
Effects of esophageal acid perfusion on airway hyperresponsiveness in patients with bronchial asthma.
    Chest, 2000, Volume: 118, Issue:6

    Topics: Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Esophagus; Female; Forc

2000
Effect of intraesophageal acid instillation on airway reactivity in patients with asthma.
    The Journal of the Association of Physicians of India, 2000, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Antacids; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-

2000
The role of age and salivation in acid clearance in symptomatic patients with gastro-oesophageal reflux disease.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:9

    Topics: Aged; Aging; Anti-Ulcer Agents; Cisapride; Deglutition; Gastroesophageal Reflux; Humans; Hydrochlori

2001
Fat and esophageal sensitivity to acid.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:3

    Topics: Adult; Dietary Fats; Drug Combinations; Esophagus; Gastroesophageal Reflux; Glycerol; Heartburn; Hum

2002
The De Carvalho and acid-barium tests in the demonstration of an unsuspected gastro-oesophageal reflux and its related oesophagitis.
    Radiologia clinica, 1975, Volume: 44, Issue:5

    Topics: Barium Sulfate; Clinical Trials as Topic; Esophagitis, Peptic; Gastroesophageal Reflux; Humans; Hydr

1975
Twenty-four-hour esophageal pH monitoring: the most useful test for evaluating noncardiac chest pain.
    The American journal of medicine, 1991, Volume: 90, Issue:5

    Topics: Adult; Aged; Ambulatory Care; Chest Pain; Edrophonium; Evaluation Studies as Topic; Female; Gastroes

1991
Intraesophageal perfusion of acid increases the bronchomotor response to methacholine and to isocapnic hyperventilation in asthmatic subjects.
    The American review of respiratory disease, 1986, Volume: 134, Issue:5

    Topics: Adolescent; Adult; Asthma; Atropine; Bronchi; Carbon Dioxide; Esophagus; Female; Gastroesophageal Re

1986
Gastro-oesophageal reflux and childhood asthma: the acid test.
    Thorax, 1985, Volume: 40, Issue:8

    Topics: Adolescent; Asthma; Bronchial Provocation Tests; Child; Female; Gastroesophageal Reflux; Histamine;

1985
[The role of acid perfusion in the diagnosis of esophageal reflux].
    Gastroenterologia, 1966, Volume: 106, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Female; Gastroesophageal Reflux; Hernia, Diaphragmatic; Human

1966

Other Studies

147 other studies available for hydrochloric acid and Esophageal Reflux

ArticleYear
Gabapentin alleviated the cough hypersensitivity and neurogenic inflammation in a guinea pig model with repeated intra-esophageal acid perfusion.
    European journal of pharmacology, 2023, Nov-15, Volume: 959

    Topics: Animals; Cough; Gabapentin; Gastroesophageal Reflux; Guinea Pigs; Hydrochloric Acid; Lung; Neurogeni

2023
Esophageal acid sensitivity in patients with gastroesophageal reflux disease: Does esophageal hypomotility matter?
    Neurogastroenterology and motility, 2019, Volume: 31, Issue:11

    Topics: Adult; Aged; Esophageal Motility Disorders; Esophageal pH Monitoring; Female; Gastroesophageal Reflu

2019
Barrett's metaplasia develops from cellular reprograming of esophageal squamous epithelium due to gastroesophageal reflux.
    American journal of physiology. Gastrointestinal and liver physiology, 2017, Jun-01, Volume: 312, Issue:6

    Topics: Barrett Esophagus; Cell Line, Transformed; Cell Lineage; Cell Shape; Cellular Reprogramming; Epithel

2017
Older Age Reduces Upper Esophageal Sphincter and Esophageal Body Responses to Simulated Slow and Ultraslow Reflux Events and Post-Reflux Residue.
    Gastroenterology, 2018, Volume: 155, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Electric Impedance; Esophageal Sphincter, Upper; Esopha

2018
Downregulation of microRNA-128-3p protects human esophageal squamous Het-1A cells from hydrochloric acid-induced cell injury by targeting E2F3.
    Die Pharmazie, 2018, 09-01, Volume: 73, Issue:9

    Topics: Apoptosis; Cell Line; Cell Proliferation; Down-Regulation; E2F3 Transcription Factor; Epithelial Cel

2018
The effect of Heweijiangni-decoction on esophageal morphology in a rat model of OVA-induced visceral hypersensitivity followed by acid exposure.
    Cellular and molecular biology (Noisy-le-Grand, France), 2019, Jun-30, Volume: 65, Issue:5

    Topics: Animals; Desmosomes; Disease Models, Animal; Drugs, Chinese Herbal; Esophagus; Extracellular Space;

2019
Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs.
    American journal of respiratory cell and molecular biology, 2014, Volume: 51, Issue:5

    Topics: Airway Remodeling; Animals; Bronchial Hyperreactivity; Calcium Channels, L-Type; Disease Models, Ani

2014
The potential of microfluidic lung epithelial wounding: towards in vivo-like alveolar microinjuries.
    Integrative biology : quantitative biosciences from nano to macro, 2014, Volume: 6, Issue:12

    Topics: Animals; Disease Models, Animal; Equipment Design; Equipment Failure Analysis; Feasibility Studies;

2014
Esophageal acid stimulation alters insular cortex functional connectivity in gastroesophageal reflux disease.
    Neurogastroenterology and motility, 2015, Volume: 27, Issue:2

    Topics: Adult; Brain Mapping; Cerebral Cortex; Female; Gastroesophageal Reflux; Gyrus Cinguli; Hippocampus;

2015
Effects of esophageal capsaicin instillation on acid induced excitation of secondary peristalsis in humans.
    Journal of gastroenterology and hepatology, 2016, Volume: 31, Issue:2

    Topics: Adult; Air; Capsaicin; Esophagus; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric A

2016
Mucosal integrity and sensitivity to acid in the proximal esophagus in patients with gastroesophageal reflux disease.
    American journal of physiology. Gastrointestinal and liver physiology, 2016, 07-01, Volume: 311, Issue:1

    Topics: Adult; Aged; Biopsy; Electric Impedance; Esophageal Mucosa; Esophagoscopy; Female; Gastric Acid; Gas

2016
Patients with Barrett's esophagus are hypersensitive to acid but hyposensitive to other stimuli compared with healthy controls.
    Neurogastroenterology and motility, 2017, Volume: 29, Issue:4

    Topics: Adult; Aged; Barrett Esophagus; Electric Stimulation; Esophagus; Female; Gastroesophageal Reflux; Ho

2017
Physicochemical basis for dilated intercellular spaces in non-erosive acid-damaged rabbit esophageal epithelium.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2008, Volume: 21, Issue:8

    Topics: Animals; Biological Transport, Active; Dilatation, Pathologic; Esophagus; Extracellular Space; Gastr

2008
Differences in activity and phosphorylation of MAPK enzymes in esophageal squamous cells of GERD patients with and without Barrett's esophagus.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 295, Issue:3

    Topics: Barrett Esophagus; Cell Line, Transformed; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21

2008
Alterations in N-methyl-D-aspartate receptor subunits in primary sensory neurons following acid-induced esophagitis in cats.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:1

    Topics: Animals; Blotting, Western; Cats; Disease Models, Animal; Eosinophil Peroxidase; Esophagitis; Esopha

2009
Experimental study on the effect of bile, and bile and hydrochloric acid mixture on the esophageal mucosa.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2009, Volume: 50, Issue:1

    Topics: Animals; Bile; Duodenum; Epithelial Cells; Esophagus; Gastroesophageal Reflux; Hydrochloric Acid; Ma

2009
Tiotropium reduction of lung inflammation in a model of chronic gastro-oesophageal reflux.
    The European respiratory journal, 2010, Volume: 35, Issue:6

    Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Atropine; Biopsy; Bronchoalveolar Lavage Fluid; Br

2010
[The expression of substance P in airway mucosa of guinea pigs with repetitive esophageal stimulation by hydrochloric acid].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2009, Volume: 32, Issue:6

    Topics: Animals; Esophagus; Gastroesophageal Reflux; Guinea Pigs; Hydrochloric Acid; Inflammation; Male; Res

2009
Does esophageal acid sensitivity alter in older adults with gastroesophageal reflux disease? A preliminary report.
    Journal of the American Geriatrics Society, 2009, Volume: 57, Issue:12

    Topics: Adult; Aged; Esophagus; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Middle Aged; Prospective

2009
Brain processing of visceral sensation upon esophageal chemical stimulation in different types of GERD.
    European journal of radiology, 2010, Volume: 75, Issue:3

    Topics: Brain; Brain Mapping; Evoked Potentials, Somatosensory; Female; Gastroesophageal Reflux; Humans; Hyd

2010
Non-erosive reflux disease (NERD), symptomatic and asymptomatic erosive reflux disease (ERD): from hypersensitive to hyposensitive esophagus.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Case-Control Studies; Disease Progression; Fem

2011
A novel external esophageal perfusion model for reflux-associated respiratory symptoms.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 2010, Volume: 77, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Feasi

2010
Altered sensorimotor responses to esophageal acidification in older adults with GERD.
    Scandinavian journal of gastroenterology, 2010, Volume: 45, Issue:10

    Topics: Adult; Age Factors; Aged; Aging; Esophageal pH Monitoring; Esophagoscopy; Esophagus; Female; Gastroe

2010
Simulated reflux decreases vocal fold epithelial barrier resistance.
    The Laryngoscope, 2010, Volume: 120, Issue:8

    Topics: Animals; Disease Models, Animal; Electric Impedance; Gastroesophageal Reflux; Gastrointestinal Agent

2010
Modulation of salivation and heartburn in response to the site of acid infusion in the human oesophagus.
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:6

    Topics: Adult; Esophagus; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Hydrogen-Ion Concen

2010
Inflammatory mediators of esophagitis alter p27 Kip1 expression in esophageal epithelial cells.
    Journal of pediatric gastroenterology and nutrition, 2010, Volume: 51, Issue:5

    Topics: Barrett Esophagus; Biological Transport; Biomarkers; Cell Line; Cell Nucleus; Cell Proliferation; Ch

2010
Anxiety increases acid-induced esophageal hyperalgesia.
    Psychosomatic medicine, 2010, Volume: 72, Issue:8

    Topics: Adult; Affect; Anxiety; Autonomic Nervous System; Baroreflex; Cross-Over Studies; Esophageal Disease

2010
The esophageal multimodal pain model: normal values and degree of sensitization in healthy young male volunteers.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:7

    Topics: Adult; Electricity; Esophagus; Gastroesophageal Reflux; Hot Temperature; Humans; Hydrochloric Acid;

2011
Experimental model of smoking and simulation of reflux with acid and pepsin in rats.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:1

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Disease Models, Animal; Gastric Mucosa; Gastroesophagea

2012
HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Sep-01, Volume: 303, Issue:5

    Topics: Adenosine Triphosphate; Aged; Blotting, Western; Cell Culture Techniques; Cytokines; Enzyme-Linked I

2012
Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation.
    The European respiratory journal, 2002, Volume: 20, Issue:2

    Topics: Animals; Asthma; Capillary Permeability; Disease Models, Animal; Esophagus; Female; Gastroesophageal

2002
Studies on the relationship between esophageal acid exposure, mucosal lesions and heartburn using an acid exposure sensor.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:11

    Topics: Adult; Animals; Cats; Diagnostic Techniques, Digestive System; Esophageal Diseases; Esophagus; Femal

2002
Oesophageal intraluminal nitric oxide facilitates the acid-induced oesophago-salivary reflex.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:3

    Topics: Adult; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Male; Nitric Oxide; Re

2003
c-Fos immunoreactivity in the brain after esophageal acid stimulation.
    The American journal of medicine, 2003, Aug-18, Volume: 115 Suppl 3A

    Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Gastroesophageal Reflux; Hydrochloric Acid; Immu

2003
THE ACID PERFUSION TEST IN THE DIFFERENTIAL DIAGNOSIS OF CHEST PAIN.
    Maryland state medical journal, 1965, Volume: 14

    Topics: Angina Pectoris; Chest Pain; Diagnosis, Differential; Esophagitis; Esophagitis, Peptic; Gastroesopha

1965
Nociceptin inhibits airway microvascular leakage induced by HCl intra-oesophageal instillation.
    British journal of pharmacology, 2004, Volume: 141, Issue:6

    Topics: Animals; Benzimidazoles; Bronchi; Capillary Permeability; Disease Models, Animal; Gastroesophageal R

2004
Autonomic responses to heartburn induced by esophageal acid infusion.
    Journal of gastroenterology and hepatology, 2004, Volume: 19, Issue:8

    Topics: Adult; Autonomic Nervous System; Case-Control Studies; Female; Gastroesophageal Reflux; Heart Rate;

2004
Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux.
    British journal of pharmacology, 2005, Volume: 144, Issue:6

    Topics: Animals; Bronchi; Bronchoconstriction; Capillary Permeability; Cough; Dose-Response Relationship, Dr

2005
Patients with gastro-oesophageal reflux disease and cough have impaired laryngopharyngeal mechanosensitivity.
    Thorax, 2005, Volume: 60, Issue:6

    Topics: Adult; Aged; Case-Control Studies; Chronic Disease; Cough; Deglutition; Endoscopy; Female; Fiber Opt

2005
Functional heartburn patients demonstrate traits of functional bowel disorder but lack a uniform increase of chemoreceptor sensitivity to acid.
    The American journal of gastroenterology, 2006, Volume: 101, Issue:5

    Topics: Autonomic Nervous System; Bacterial Proteins; Chemoreceptor Cells; Endoscopy, Gastrointestinal; Esop

2006
Effect of acid and pepsin on glottic wound healing: a simulated reflux model.
    Archives of otolaryngology--head & neck surgery, 2006, Volume: 132, Issue:9

    Topics: Animals; Disease Models, Animal; Gastroesophageal Reflux; Glottis; Hydrochloric Acid; Male; Pepsin A

2006
Cannabinoid CB(2) receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux.
    European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3

    Topics: Airway Obstruction; Animals; Benzoxazines; Bronchi; Bronchoconstriction; Camphanes; Cannabinoids; Ca

2007
Airway responses to esophageal acidification.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:1

    Topics: Airway Resistance; Animals; Bronchi; Cats; Disease Models, Animal; Esophagus; Female; Gastroesophage

2008
Acid-related oesophageal sensitivity, not dysmotility, differentiates subgroups of patients with non-erosive reflux disease.
    Alimentary pharmacology & therapeutics, 2008, Mar-01, Volume: 27, Issue:5

    Topics: Adult; Case-Control Studies; Esophageal Motility Disorders; Esophagoscopy; Female; Gastroesophageal

2008
Laryngeal stimulation by an acid solution in the pre-term lamb.
    Advances in experimental medicine and biology, 2008, Volume: 605

    Topics: Aging; Animals; Animals, Newborn; Citric Acid; Disease Models, Animal; Gastroesophageal Reflux; Hydr

2008
The protective effect of TiF4, SnF2 and NaF against erosion-like lesions in situ.
    Caries research, 2008, Volume: 42, Issue:1

    Topics: Adult; Cariostatic Agents; Dental Enamel; Female; Fluorides; Gastroesophageal Reflux; Humans; Hydroc

2008
Neurocognitive processing of esophageal central sensitization in the insula and cingulate gyrus.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:3

    Topics: Adolescent; Adult; Catheterization; Cerebral Cortex; Cognition; Dilatation; Esophagus; Female; Gastr

2008
Comparison of airway responses following tracheal or esophageal acidification in the cat.
    Gastroenterology, 1984, Volume: 87, Issue:4

    Topics: Airway Resistance; Animals; Cats; Esophagitis; Esophagus; Female; Gastroesophageal Reflux; Hydrochlo

1984
Solid-bolus passage in patients with pathological oesophageal acid clearing.
    Scandinavian journal of gastroenterology, 1983, Volume: 18, Issue:2

    Topics: Acids; Esophagus; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Middle Aged; Radionuclide Imag

1983
Esophageal acid perfusion in coronary artery disease. Induction of myocardial ischemia.
    Gastroenterology, 1983, Volume: 85, Issue:2

    Topics: Angina Pectoris; Angiography; Blood Pressure; Cardiomyopathies; Coronary Disease; Diagnosis, Differe

1983
Characteristics of esophageal pain.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 644

    Topics: Diagnosis, Differential; Food; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Pain;

1981
Radionuclide studies of esophageal transit and gastroesophageal reflux.
    Seminars in nuclear medicine, 1982, Volume: 12, Issue:2

    Topics: Adult; Aged; Biopsy; Child; Deglutition; Esophagoscopy; Esophagus; Female; Gastroesophageal Reflux;

1982
The role of the esophageal body in the antireflux mechanism.
    Surgery, 1982, Volume: 92, Issue:2

    Topics: Cardia; Esophagogastric Junction; Esophagus; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hyd

1982
Spontaneous peristaltic activity in the oesophagus after imitated acid gastro-oesophageal reflux. A study in normal subjects.
    Scandinavian journal of gastroenterology, 1982, Volume: 17, Issue:6

    Topics: Adult; Esophagus; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Ma

1982
Bronchial obstruction after oesophageal acid perfusion in asthmatics.
    Clinical physiology (Oxford, England), 1981, Volume: 1, Issue:3

    Topics: Adult; Aged; Asthma; Closing Volume; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Lun

1981
Lower esophageal sphincter pressure as an index of gastroesophageal acid reflux.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:11

    Topics: Esophagogastric Junction; Gastric Acid; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hydrogen

1981
Role of diagnostic tests in esophageal evaluation.
    American journal of surgery, 1980, Volume: 139, Issue:6

    Topics: Biopsy; Esophageal Diseases; Esophagitis; Esophagoscopy; Esophagus; Gastroesophageal Reflux; Humans;

1980
Acid-sensitive oesophagus.
    Scandinavian journal of gastroenterology, 1980, Volume: 15, Issue:3

    Topics: Adult; Aged; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochlo

1980
Effects of acid and bile salts on the rabbit esophageal mucosa.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:1

    Topics: Animals; Bile Acids and Salts; Esophagitis, Peptic; Esophagus; Gastroesophageal Reflux; Hydrochloric

1981
Modulatory impact of acid and pepsin on esophageal hydrophobicity in humans.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:11

    Topics: Adult; Esophagitis, Peptic; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; M

1995
Role of gastroesophageal reflux disease in patients with cervical symptoms.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1995, Volume: 113, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barium Sulfate; Biopsy; Cineradiograp

1995
Esophageal dysmotility elicited by acid perfusion in children with esophagitis.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:7

    Topics: Adolescent; Child; Esophageal Motility Disorders; Esophagitis; Esophagus; Female; Gastroesophageal R

1995
Esophageal shortening induced by short-term intraluminal acid perfusion in opossum: a cause for hiatus hernia?
    Gastroenterology, 1994, Volume: 107, Issue:6

    Topics: Animals; Atropine; Constriction, Pathologic; Disease Models, Animal; Epithelium; Esophagus; Female;

1994
Gastroesophageal reflux-induced bronchoconstriction. An intraesophageal acid infusion study using state-of-the-art technology.
    Chest, 1994, Volume: 106, Issue:3

    Topics: Adult; Analysis of Variance; Asthma; Bronchoconstriction; Chi-Square Distribution; Chronic Disease;

1994
Are esophageal symptoms reflux-related? A study of different scoring systems in a cohort of patients with heartburn.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:4

    Topics: Cohort Studies; Endoscopy, Digestive System; Esophagitis, Peptic; Female; Gastroesophageal Reflux; H

1994
Interrelationship between esophageal challenge with mechanical and chemical stimuli and salivary protective mechanisms.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:4

    Topics: Adult; Catheterization; Chemoreceptor Cells; Esophagus; Female; Gastroesophageal Reflux; Humans; Hyd

1994
Impact of acid and pepsin on human esophageal prostaglandins.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:4

    Topics: Adult; Catheterization; Dinoprostone; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochlor

1994
[The effect of experimental gastroesophageal reflux on the cough reflex in anesthetized cats].
    Bratislavske lekarske listy, 1996, Volume: 97, Issue:5

    Topics: Anesthesia; Animals; Capsaicin; Cats; Cough; Esophagus; Female; Gastroesophageal Reflux; Hydrochlori

1996
Cardio-oesophageal reflex in humans as a mechanism for "linked angina'.
    European heart journal, 1996, Volume: 17, Issue:3

    Topics: Adult; Aged; Chest Pain; Coronary Circulation; Esophagus; Exercise Test; Female; Gastroesophageal Re

1996
Modulatory effect of esophageal intraluminal mechanical and chemical stressors on salivary prostaglandin E2 in humans.
    The American journal of the medical sciences, 1997, Volume: 313, Issue:2

    Topics: Adult; Catheterization; Dinoprostone; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochlor

1997
Oesophageal acid and salivary secretion: is chewing gum a treatment option for gastro-oesophageal reflux?
    Digestion, 1997, Volume: 58, Issue:2

    Topics: Adult; Chewing Gum; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Male; Sal

1997
The resistance of titanium tetrafluoride-treated human enamel to strong hydrochloric acid.
    European journal of oral sciences, 1997, Volume: 105, Issue:5 Pt 2

    Topics: Cariostatic Agents; Dental Enamel; Dental Enamel Solubility; Fluorides; Gastric Acid; Gastroesophage

1997
Role of mast cell-derived mediators in acid-induced shortening of the esophagus.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Animals; Bronchodilator Agents; Constriction, Pathologic; Cromolyn Sodium; Disease Models, Animal; E

1998
Effects of HCl-pepsin laryngeal instillations on upper airway patency-maintaining mechanisms.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:4

    Topics: Animals; Catheterization; Dogs; Gastroesophageal Reflux; Hydrochloric Acid; Laryngeal Muscles; Laryn

1998
The effects of acid perfusion of the esophagus on ventilation and respiratory sensation.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:4 Pt 1

    Topics: Asthma; Diaphragm; Electromyography; Esophagus; Female; Forced Expiratory Volume; Gastroesophageal R

1998
Experimental study of acid burden and acute oesophagitis.
    The British journal of surgery, 1998, Volume: 85, Issue:5

    Topics: Acute Disease; Animals; Cats; Esophagitis; Gastric Acid; Gastroesophageal Reflux; Hydrochloric Acid;

1998
Effects of simulated gastroesophageal reflux on the untraumatized rabbit larynx.
    The Journal of otolaryngology, 1998, Volume: 27, Issue:3

    Topics: Animals; Female; Gastroesophageal Reflux; Hydrochloric Acid; Laryngitis; Male; Rabbits; Random Alloc

1998
Initiation and perpetuation of gastroesophageal reflux disease.
    Gastroenterology, 1998, Volume: 115, Issue:5

    Topics: Animals; Cromolyn Sodium; Esophagus; Gastroesophageal Reflux; Hydrochloric Acid; Mast Cells; Opossum

1998
[Value of tests other than endoscopy and esophageal ph monitoring in the diagnosis of gastroesophageal reflux].
    Gastroenterologie clinique et biologique, 1999, Volume: 23, Issue:1 Pt 2

    Topics: Barium Sulfate; Esophageal Motility Disorders; Gastrins; Gastroesophageal Reflux; Hernia, Hiatal; Hu

1999
Proximal migration of esophageal acid perfusions during waking and sleep.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:1

    Topics: Adult; Esophagus; Female; Gastric Acid; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hydrogen

2000
Acid/pepsin promotion of carcinogenesis in the hamster cheek pouch.
    Archives of otolaryngology--head & neck surgery, 2000, Volume: 126, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Gastric Acid;

2000
Symptom severity and oesophageal chemosensitivity to acid in older and young patients with gastro-oesophageal reflux.
    Age and ageing, 2000, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochlo

2000
The potential role of the esophageal pre-epithelial barrier components in the maintenance of integrity of the esophageal mucosa in patients with endoscopically negative gastroesophageal reflux disease.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:7

    Topics: Adult; Epithelium; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hydrogen-I

2000
Simulated reflux and laryngotracheal reconstruction: a rabbit model.
    Archives of otolaryngology--head & neck surgery, 2001, Volume: 127, Issue:5

    Topics: Animals; Cartilage; Disease Models, Animal; Feasibility Studies; Gastroesophageal Reflux; Hydrochlor

2001
Airway protection following simulated gastro-oesophageal reflux in sedated and sleeping neonatal piglets during active sleep.
    Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:7

    Topics: Animals; Animals, Newborn; Apnea; Deglutition; Electroencephalography; Electrooculography; Esophagus

2001
Function of the eustachian tube after weekly exposure to pepsin/hydrochloric acid.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2001, Volume: 125, Issue:3

    Topics: Animals; Eustachian Tube; Gastroesophageal Reflux; Gastrointestinal Agents; Hydrochloric Acid; Model

2001
Duodenal fat intensifies the perception of heartburn.
    Gut, 2001, Volume: 49, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Anti-Ulcer Agents; Dietary Fats; Dose-Response Relationship, Drug

2001
Transient inflammation and dysfunction of the eustachian tube secondary to multiple exposures of simulated gastroesophageal refluxant.
    The Annals of otology, rhinology, and laryngology, 2001, Volume: 110, Issue:10

    Topics: Animals; Ear, Middle; Eustachian Tube; Gastroesophageal Reflux; Hydrochloric Acid; Otitis Media; Pep

2001
Transient inflammation and dysfunction of the eustachian tube secondary to multiple exposures of simulated gastroesophageal refluxant.
    The Annals of otology, rhinology, and laryngology, 2001, Volume: 110, Issue:10

    Topics: Animals; Ear, Middle; Eustachian Tube; Gastroesophageal Reflux; Hydrochloric Acid; Otitis Media; Pep

2001
Transient inflammation and dysfunction of the eustachian tube secondary to multiple exposures of simulated gastroesophageal refluxant.
    The Annals of otology, rhinology, and laryngology, 2001, Volume: 110, Issue:10

    Topics: Animals; Ear, Middle; Eustachian Tube; Gastroesophageal Reflux; Hydrochloric Acid; Otitis Media; Pep

2001
Transient inflammation and dysfunction of the eustachian tube secondary to multiple exposures of simulated gastroesophageal refluxant.
    The Annals of otology, rhinology, and laryngology, 2001, Volume: 110, Issue:10

    Topics: Animals; Ear, Middle; Eustachian Tube; Gastroesophageal Reflux; Hydrochloric Acid; Otitis Media; Pep

2001
Effect of changes in the intragastric milieu on competence of the gastro-oesophageal region. A study in normal subjects.
    Scandinavian journal of gastroenterology, 1977, Volume: 12, Issue:2

    Topics: Adult; Blood Glucose; Esophagogastric Junction; Female; Gastric Juice; Gastroesophageal Reflux; Huma

1977
Diagnosis of symptomatic gastroesophageal reflux by prolonged monitoring of lower esophageal pH.
    Scandinavian journal of gastroenterology, 1977, Volume: 12, Issue:6

    Topics: Adult; Esophagitis, Peptic; Esophagoscopy; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydro

1977
Gastroesophageal reflux in children: evaluation of the water siphon test.
    Radiology, 1979, Volume: 131, Issue:2

    Topics: Adolescent; Barium Sulfate; Child; Child, Preschool; Esophagogastric Junction; Evaluation Studies as

1979
[Comparison of the value of various methods for diagnosis of gastroesophageal reflux].
    Chirurgisches Forum fur experimentelle und klinische Forschung, 1978, Issue:1978

    Topics: Diagnosis, Differential; Esophagitis, Peptic; Esophagoscopy; Evaluation Studies as Topic; Gastroesop

1978
Effect of bile salts on the ionic permeability of the esophageal mucosa and their role in the production of esophagitis.
    Gastroenterology, 1975, Volume: 68, Issue:4 Pt 1

    Topics: Animals; Bile; Bile Acids and Salts; Dogs; Esophagitis; Esophagitis, Peptic; Esophagus; Gastric Juic

1975
Effect of cholinergic blockade on postprandial and acid-stimulated lower esophageal sphincter pressure.
    The American surgeon, 1978, Volume: 44, Issue:12

    Topics: Animals; Atropine; Dogs; Esophagogastric Junction; Food; Gastroesophageal Reflux; Hydrochloric Acid;

1978
The acid reflux test for gastroesophageal reflux.
    The Journal of pediatrics, 1979, Volume: 94, Issue:1

    Topics: Child; Esophagogastric Junction; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Infant; Methods

1979
The acid perfusion test. A study in patients with symptomatic hiatus hernia, and of the effect of a modified Belsey MK IV repair on the test.
    Scandinavian journal of gastroenterology, 1977, Volume: 12, Issue:2

    Topics: Adult; Aged; Bicarbonates; Female; Gastroesophageal Reflux; Hernia, Diaphragmatic; Hernia, Hiatal; H

1977
Oesophagoscopy, biopsy, and acid perfusion test in diagnosis of "reflux oesophagitis".
    British medical journal, 1975, Jan-11, Volume: 1, Issue:5949

    Topics: Adult; Biopsy; Endoscopy; Esophagitis; Esophagus; Gastroesophageal Reflux; Humans; Hydrochloric Acid

1975
Epigastric pain in duodenal ulcer.
    British medical journal, 1975, May-03, Volume: 2, Issue:5965

    Topics: Bicarbonates; Duodenal Ulcer; Esophagogastric Junction; Gastroesophageal Reflux; Humans; Hydrochlori

1975
Esophageal function in progressive systemic sclerosis.
    Acta hepato-gastroenterologica, 1976, Volume: 23, Issue:1

    Topics: Adult; Aged; Biopsy; Cineradiography; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochlor

1976
Gastro-oesophageal reflux disease: correlation of subjective symptoms with 7 objective oesophageal function tests.
    Acta hepato-gastroenterologica, 1976, Volume: 23, Issue:2

    Topics: Biopsy; Female; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Hydrochloric Acid; Male; Man

1976
Acid perfusion and edrophonium provocation tests in patients with chest pain of undetermined etiology.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:8

    Topics: Adult; Aged; Chest Pain; Chi-Square Distribution; Circadian Rhythm; Diagnosis, Differential; Edropho

1992
Symptomatic gastro-oesophageal reflux, abnormal oesophageal acid exposure, and mucosal acid sensitivity are three separate, though related, aspects of gastro-oesophageal reflux disease.
    Gut, 1991, Volume: 32, Issue:2

    Topics: Adult; Chest Pain; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Hydrogen-I

1991
Acid perfusion test and 24-hour esophageal pH monitoring with symptom index. Comparison of tests for esophageal acid sensitivity.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:5

    Topics: Chest Pain; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration;

1991
[Acidic stimulation of esophageal peristalsis: its prognostic value in reflux].
    Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica, 1990, Volume: 3, Issue:2

    Topics: Child; Esophageal Motility Disorders; Esophagus; Gastroesophageal Reflux; Humans; Hydrochloric Acid;

1990
Acid-induced esophagobronchial-cardiac reflexes in humans.
    Gastroenterology, 1990, Volume: 99, Issue:1

    Topics: Atropine; Bronchi; Esophagus; Gastroesophageal Reflux; Heart Rate; Humans; Hydrochloric Acid; Manome

1990
Effects of spontaneous and simulated gastroesophageal reflux on sleeping asthmatics.
    The American review of respiratory disease, 1990, Volume: 141, Issue:6

    Topics: Adult; Airway Resistance; Asthma; Bronchial Spasm; Esophagitis, Peptic; Female; Gastroesophageal Ref

1990
Acid perfusion test: does it have a role in the assessment of non cardiac chest pain?
    Gut, 1989, Volume: 30, Issue:3

    Topics: Adult; Aged; Chest Pain; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hydr

1989
Serosal bicarbonate protects against acid injury to rabbit esophagus.
    Gastroenterology, 1989, Volume: 96, Issue:6

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Animals; Bicarbonates; Es

1989
Absence of an upper esophageal sphincter response to acid reflux.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:6

    Topics: Adult; Esophagitis, Peptic; Esophagogastric Junction; Gastroesophageal Reflux; Humans; Hydrochloric

1989
Esophageal acid perfusion, airway function, and symptoms in asthmatic patients with marked bronchial hyperreactivity.
    Chest, 1989, Volume: 96, Issue:5

    Topics: Aged; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Circadian Rhythm; Esophagus; Fe

1989
Oesophageal stimulation lowers exertional angina threshold.
    Lancet (London, England), 1985, May-04, Volume: 1, Issue:8436

    Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Electrocardiography; Esophagus; Exercise Test; Femal

1985
[Gastroesophageal reflux in asthmatic and chronic bronchitis patients].
    Allergie et immunologie, 1988, Volume: 20, Issue:6

    Topics: Adult; Aged; Asthma; Bronchitis; Chronic Disease; Diaphragm; Female; Gastroesophageal Reflux; Humans

1988
Specificity and sensitivity of objective diagnosis of gastroesophageal reflux disease.
    Surgery, 1987, Volume: 102, Issue:4

    Topics: Esophagoscopy; Esophagus; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Hydrochloric A

1987
Preservation of lower esophageal sphincter asymmetry after acid-induced abolition of the high pressure zone.
    The American surgeon, 1986, Volume: 52, Issue:8

    Topics: Animals; Cats; Esophagitis; Esophagogastric Junction; Esophagoscopy; Esophagus; Gastroesophageal Ref

1986
Distinction of lower esophageal sphincter strength from sphincter competence.
    American journal of surgery, 1987, Volume: 153, Issue:1

    Topics: Animals; Atropine; Cats; Esophagogastric Junction; Gastroesophageal Reflux; Hydrochloric Acid; Manom

1987
Gastroesophageal reflux in patients with asthma and chronic bronchitis.
    The American review of respiratory disease, 1987, Volume: 135, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Asthma; Bronchitis; Chronic Disease; Diaphragm; Esophagus; Female; G

1987
Esophageal blood flow in the cat. Normal distribution and effects of acid perfusion.
    Gastroenterology, 1986, Volume: 90, Issue:3

    Topics: Animals; Cats; Esophagogastric Junction; Esophagus; Gastric Acid; Gastroesophageal Reflux; Hydrochlo

1986
Esophageal function, radiography, and dysphagia in Sjögren's syndrome.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:3

    Topics: Adult; Aged; Deglutition Disorders; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Re

1986
Hiatus hernia in gastroesophageal reflux disease.
    Scandinavian journal of gastroenterology, 1986, Volume: 21, Issue:1

    Topics: Barium Sulfate; Duodenoscopy; Enema; Esophagitis, Peptic; Esophagoscopy; Fiber Optic Technology; Gas

1986
The acid perfusion test in gastroesophageal reflux disease.
    Scandinavian journal of gastroenterology, 1986, Volume: 21, Issue:1

    Topics: Adult; Aged; Duodenoscopy; Esophagitis, Peptic; Esophagoscopy; Female; Fiber Optic Technology; Gastr

1986
Are esophageal motility abnormalities produced during the intraesophageal acid perfusion test?
    JAMA, 1985, Apr-05, Volume: 253, Issue:13

    Topics: Adult; Deglutition; Esophagus; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Manome

1985
Oesophageal motility during acid-provoked heartburn and chest pain.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:8

    Topics: Adult; Aged; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Reflux; Gastrointestinal

1985
Oesophageal acid-perfusion in the diagnosis of precordial pain.
    Lancet (London, England), 1966, Nov-26, Volume: 2, Issue:7474

    Topics: Angina Pectoris; Diagnosis, Differential; Esophagitis; Gastroesophageal Reflux; Humans; Hydrochloric

1966
Relationship between motor changes and pain during esophageal acid perfusion.
    The American journal of digestive diseases, 1968, Volume: 13, Issue:4

    Topics: Bicarbonates; Esophagoscopy; Esophagus; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Hydr

1968
[Clinical evaluation of hiatal hernias].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Apr-01, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Biopsy; Contrast Media; Diagnosis, Differential; Esophagitis; Gastroesophageal Re

1974
[Therapeutic problems of chronic gastroenterologic diseases].
    Fortschritte der Medizin, 1973, Jul-05, Volume: 91, Issue:19

    Topics: Aluminum Hydroxide; Chronic Disease; Gastritis; Gastroesophageal Reflux; Gastrointestinal Diseases;

1973
Synergism of acid and bile salts in the production of experimental esophagitis.
    Canadian journal of surgery. Journal canadien de chirurgie, 1973, Volume: 16, Issue:1

    Topics: Animals; Autopsy; Bile; Bile Acids and Salts; Biopsy; Dogs; Drug Synergism; Esophagitis; Esophagosco

1973
Gastroesophageal reflux: diagnosis and treatment.
    Annals of surgery, 1973, Volume: 177, Issue:5

    Topics: Adult; Aged; Cineradiography; Esophagitis; Esophagogastric Junction; Esophagoscopy; Female; Gastroes

1973
[Surgical therapy of esophageal erosions and their consequences].
    Bruns' Beitrage fur klinische Chirurgie, 1973, Volume: 220, Issue:8

    Topics: Adolescent; Adult; Burns, Chemical; Child; Child, Preschool; Dilatation; Esophageal Diseases; Esopha

1973
The acid-barium test as an index of intermittent gastro-oesophageal reflux.
    The British journal of radiology, 1973, Volume: 46, Issue:548

    Topics: Barium Sulfate; Deglutition; Fluoroscopy; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric A

1973
Lack of specificity of the acid perfusion test in duodenal ulcer patients.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:9

    Topics: Adult; Duodenal Ulcer; Duodenum; Esophagitis, Peptic; Esophagoscopy; Esophagus; Evaluation Studies a

1974
Upper oesophageal sphincter yield pressure in normal subjects and in patients with gastro-oesophageal reflux.
    Thorax, 1974, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aged; Catheterization; Esophagitis; Esophagoscopy; Esophagus; Female; Gastroesoph

1974
Acid reactivity in the distal esophagus.
    Military medicine, 1970, Volume: 135, Issue:8

    Topics: Adolescent; Adult; Alkalies; Animals; Dogs; Esophagitis, Peptic; Esophagogastric Junction; Esophagus

1970
Hiatus hernia and oesophageal reflux. Methods of investigation. I.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:1

    Topics: Biopsy; Esophagitis; Esophagoscopy; Esophagus; Gastric Acidity Determination; Gastric Juice; Gastroe

1972
Obscure chest pain as a symptom of reflux esophagitis.
    The Medical clinics of North America, 1972, Volume: 56, Issue:3

    Topics: Adult; Aged; Deglutition Disorders; Endoscopy; Esophagitis; Female; Gastroesophageal Reflux; Gastroi

1972
The role of bile and acid in the production of esophagitis and the motor defect of esophagitis.
    The Annals of thoracic surgery, 1972, Volume: 14, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Deglutition Disorders; Dogs; Esophagitis, Peptic; Esophagogastr

1972
[Esophageal acid instillation test in pregnant women with pyrosis].
    Revista espanola de las enfermedades del aparato digestivo, 1971, Jun-15, Volume: 34, Issue:6

    Topics: Adult; Esophagus; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Methods; Pe

1971
Two cases of dental erosion related to the swallowing pattern.
    The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1968, Volume: 23, Issue:1

    Topics: Achlorhydria; Adult; Deglutition; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Male;

1968
Effect of pH changes on the cardiac sphincter.
    Gut, 1969, Volume: 10, Issue:10

    Topics: Atropine; Cardia; Digestion; Esophagogastric Junction; Gastric Mucosa; Gastroesophageal Reflux; Huma

1969
[The acid perfusion test in the diagnosis of reflux esophagitis].
    Deutsche medizinische Wochenschrift (1946), 1970, Jan-02, Volume: 95, Issue:1

    Topics: Esophagoscopy; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Methods; Perfusion

1970
Assessment of distal esophageal function in patients with hiatal hernia and-or gastroesophageal reflux.
    Annals of surgery, 1970, Volume: 172, Issue:4

    Topics: Adolescent; Adult; Aged; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Reflux; Gastr

1970
Globus hystericus--a manifestation of reflux oesophagitis?
    The Journal of laryngology and otology, 1970, Volume: 84, Issue:10

    Topics: Adult; Barium Sulfate; Female; Fluoroscopy; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans;

1970
Mechanism of pyrosis. A clinical study.
    The American journal of digestive diseases, 1971, Volume: 16, Issue:7

    Topics: Gastric Acidity Determination; Gastroesophageal Reflux; Gastrointestinal Motility; Heartburn; Hernia

1971
Uses of esophageal manometry and acid perfusion in the study of gastroesophageal reflux and hiatal hernia.
    The Surgical clinics of North America, 1971, Volume: 51, Issue:3

    Topics: Esophagus; Gastric Acidity Determination; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Hy

1971
Effect of oesophageal perfusion with acid on basal gastric secretion.
    Gut, 1968, Volume: 9, Issue:1

    Topics: Adult; Duodenal Ulcer; Esophagitis, Peptic; Esophagus; Gastric Juice; Gastric Mucosa; Gastroesophage

1968
Acid clearing from the distal esophagus.
    Archives of surgery (Chicago, Ill. : 1960), 1968, Volume: 96, Issue:5

    Topics: Deglutition; Esophagitis; Esophagus; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Hydroch

1968
The esophageal acid perfusion test.
    Lahey Clinic Foundation bulletin, 1965, Volume: 14, Issue:2

    Topics: Adult; Esophagitis, Peptic; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Male; Middle

1965