hydrochloric acid has been researched along with Disease Models, Animal in 198 studies
Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
Excerpt | Relevance | Reference |
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" Hydrochloric acid (HCl) has been used to induce inflammation in the lungs and stomach but not tested for reproductive organs." | 7.83 | Establishment of hydrochloric acid/lipopolysaccharide-induced pelvic inflammatory disease model. ( Hahn, TW; Han, JH; Jung, BD; Kim, HC; Koo, DB; Kwon, YS; Lee, J; Oh, Y; Park, JJ; Rhee, KJ; Yoon, BI, 2016) |
"We investigated the effect of the multi-herbal medicine, WSY-1075 in an animal model of hydrochloric acid (HCl)-induced cystitis." | 7.81 | Reduction of oxidative stress may play a role in the anti-inflammatory effect of the novel herbal formulation in a rat model of hydrochloric acid-induced cystitis. ( Bae, WJ; Ha, US; Hong, SH; Hwang, SY; Hwang, TK; Kim, HJ; Kim, S; Kim, SJ; Kim, SW; Lee, JY, 2015) |
"To clarify the basic mechanism involved in the pathophysiology of cystitis by characterizing the urodynamic parameters, pharmacologically relevant (muscarinic and purinergic) receptors, and the in vivo release of adenosine triphosphate (ATP) in the bladder of hydrochloric acid (HCl)-treated rats." | 7.76 | Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. ( Fujino, T; Kageyama, A; Nozawa, Y; Yamada, S; Yoshida, A, 2010) |
"We investigated the effect of diacerein, an antiosteoarthritic agent, and its metabolite, rhein, on the production of reactive oxygen species (ROS) from neutrophils as well as the protective effect of diacerein on indomethacin-induced gastric ulceration and its protection mechanism." | 7.71 | Effects of diacerein on indomethacin-induced gastric ulceration. ( Ohmori, K; Tamura, T; Yokoyama, T, 2001) |
"Effect of superimposed high frequency oscillatory ventilation on pulmonary gas exchange was investigated in seven anesthetized and paralyzed dogs with pulmonary edema induced by intrapulmonary injection of hydrochloric acid." | 7.68 | [Effect of superimposed high frequency oscillation on pulmonary edema induced by intrapulmonary injection of hydrochloric acid in dogs]. ( Sakai, T; Takaori, M; Yoshida, H, 1991) |
"Previous abdominal aortic aneurysm (AAA) animal modeling methodologies were either expensive or complicated." | 5.91 | A novel abdominal aortic aneurysm model produced by periarterial application of hydrochloric acid. ( Chang, X; Duan, C; Guo, W; Wei, R; Wu, Z; Xiong, J, 2023) |
"Selective intra-bronchial instillation of hydrochloric acid (HCl) to the murine left mainstem bronchus causes acute tissue injury with histopathologic findings similar to human acute respiratory distress syndrome (ARDS)." | 3.91 | A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation. ( Abdulnour, RE; Colby, JK; Levy, BD; Tavares, AH, 2019) |
" Hydrochloric acid (HCl) has been used to induce inflammation in the lungs and stomach but not tested for reproductive organs." | 3.83 | Establishment of hydrochloric acid/lipopolysaccharide-induced pelvic inflammatory disease model. ( Hahn, TW; Han, JH; Jung, BD; Kim, HC; Koo, DB; Kwon, YS; Lee, J; Oh, Y; Park, JJ; Rhee, KJ; Yoon, BI, 2016) |
"We investigated the effect of the multi-herbal medicine, WSY-1075 in an animal model of hydrochloric acid (HCl)-induced cystitis." | 3.81 | Reduction of oxidative stress may play a role in the anti-inflammatory effect of the novel herbal formulation in a rat model of hydrochloric acid-induced cystitis. ( Bae, WJ; Ha, US; Hong, SH; Hwang, SY; Hwang, TK; Kim, HJ; Kim, S; Kim, SJ; Kim, SW; Lee, JY, 2015) |
"5% hypertonic saline in an experimental model of acute lung injury induced by hydrochloric acid." | 3.81 | Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs. ( Auler Junior, JO; Fantoni, DT; Gutierrez, PS; Holms, CA; Kahvegian, M; Massoco, CO; Otsuki, DA, 2015) |
"Aspiration of hydrochloric acid (HCl)-containing gastric juice leads to acute lung injury (ALI) and hypoxemic respiratory failure due to an exuberant inflammatory response associated with pulmonary edema from increased vascular and epithelial permeability." | 3.78 | Acid-induced acute lung injury in mice is associated with P44/42 and c-Jun N-terminal kinase activation and requires the function of tumor necrosis factor α receptor I. ( Armaganidis, A; Kollias, G; Kotanidou, A; Magkou, C; Maniatis, NA; Nikitopoulou, I; Orfanos, SE; Roussos, C; Sfika, A; Vassiliou, AG, 2012) |
"Zerumbone (1) showed potent cytoprotective effect against necrotizing agent (HCl) and non-steroidal anti-inflammatory drug (indomethacin) induced gastric ulceration." | 3.78 | Antiulcer principle from Zingiber montanum. ( Al-Amin, M; Hossain, CF; Sultana, GN, 2012) |
"To develop experimental models to evaluate the effects of hydrochloric acid associated with the pepsin instilled in the mucosa of the upper esophagus and the esophagogastric junction of young male rats Wistar, simulating injury caused by gastroesophageal reflux on the mucosa of aero-digestive tract in humans as well as the action of the risk exposure of mucosa to cigarette smoke." | 3.78 | Experimental model of smoking and simulation of reflux with acid and pepsin in rats. ( Altemani, AM; Andreollo, NA; Araujo, MR; Colli Neto, JA; Del Negro, A; Zen Junior, JH, 2012) |
" The aim of this work was to assess the gastroprotective effect of amino acid amides from imbricatolic acid and its 8(9)-en isomer in the ethanol/HCl-induced gastric lesions model in mice as well as to determine the cytotoxicity of the obtained compounds on the following human cell lines: normal lung fibroblasts (MRC-5), gastric adenocarcinoma (AGS), and liver hepatocellular carcinoma (Hep G2)." | 3.77 | Gastroprotective effect and cytotoxicity of labdeneamides with amino acids. ( Rodríguez, JA; Schmeda-Hirschmann, G; Theoduloz, C; Valderrama, JA, 2011) |
" Acute gastric ulcer was induced using absolute ethanol, HCl/ethanol and indomethacin." | 3.77 | Antiulcerogenic activity of the essential oil of Hyptis martiusii Benth. (Lamiaceae). ( Caldas, GF; da Costa, JG; da Nóbrega, RF; da Silva, JB; do Amaral Costa, IM; Rodrigues, FF; Wanderley, AG, 2011) |
" Finally, whether Pa-EE was orally available, ethanol (EtOH)/hydrochloric acid (HCl)-induced gastritis model in mice was used." | 3.77 | Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans. ( Ahn, HM; Cha, SH; Cho, JY; Han, MH; Jang, HJ; Kim, C; Kim, JH; Kim, SY; Kim, TW; Lee, J; Lee, YJ; Shen, T; Yang, HM; Yoon, K; Yu, T, 2011) |
"To clarify the basic mechanism involved in the pathophysiology of cystitis by characterizing the urodynamic parameters, pharmacologically relevant (muscarinic and purinergic) receptors, and the in vivo release of adenosine triphosphate (ATP) in the bladder of hydrochloric acid (HCl)-treated rats." | 3.76 | Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. ( Fujino, T; Kageyama, A; Nozawa, Y; Yamada, S; Yoshida, A, 2010) |
"Stomach ulcers were induced by oral ingestion of hydrochloride (HCl)/ethanol or indomethacin." | 3.76 | Protective effects of a gastrointestinal agent containing Korean red ginseng on gastric ulcer models in mice. ( Hara, H; Kakino, M; Ogawa, K; Oyagi, A, 2010) |
"The gastroprotective effect of the sesquiterpene cyperenoic acid and seven semi-synthetic derivatives was assessed in the HCl/ethanol-induced gastric ulcer model in mice." | 3.73 | Gastroprotective activity and cytotoxic effect of cyperenoic acid derivatives. ( Pertino, M; Razmilic, I; Rodríguez, JA; Schmeda-Hirschmann, G; Theoduloz, C, 2006) |
" In a chronic model, by acetic acid-induced gastric ulcers, COX-2 was expressed at 7 days and was also associated with PGE(2) increase." | 3.73 | COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions. ( Alarcón de la Lastra, C; Bruseghini, L; Manuel Herrerias, J; Motilva, V; Sánchez-Fidalgo, S, 2005) |
"The effects of beta-cyclodextrin (betaCD) inclusion complexation on the ability of violacein to prevent gastric ulceration in mice were studied." | 3.72 | Evaluation of the antiulcerogenic activity of violacein and its modulation by the inclusion complexation with beta-cyclodextrin. ( Almeida, AB; Brito, AR; De Azevedo, MB; Durán, N; Haun, M; Justo, GZ; Melo, PS, 2003) |
"The double indicator method is useful for evaluation of pulmonary edema in indirect lung injury, as induced by oleic acid, but produces misleading values in direct lung injury, as produced by hydrochloric instillation." | 3.72 | Accuracy of the double indicator method for measurement of extravascular lung water depends on the type of acute lung injury. ( Auffray, JP; Bregeon, F; Carpentier, JP; Delliaux, S; Ghez, O; Lambert, D; Michelet, P; Papazian, L; Perrin, G; Roch, A; Saby, C; Thomas, P, 2004) |
" Laryngospasm was associated with prolonged apnea and total cessation of diaphragmatic EMG activity in 1 animal, and in another, initial tachypnea was followed by erratic diaphragmatic activity and brief apnea." | 3.71 | Laryngospasm and diaphragmatic arrest in immature dogs after laryngeal acid exposure: a possible model for sudden infant death syndrome. ( Averill, DB; Duke, SG; Koufman, JA; McGuirt, WF; Postma, GN; Ririe, D, 2001) |
"We investigated the effect of diacerein, an antiosteoarthritic agent, and its metabolite, rhein, on the production of reactive oxygen species (ROS) from neutrophils as well as the protective effect of diacerein on indomethacin-induced gastric ulceration and its protection mechanism." | 3.71 | Effects of diacerein on indomethacin-induced gastric ulceration. ( Ohmori, K; Tamura, T; Yokoyama, T, 2001) |
"We investigated the effect of probucol, a lipid-lowering agent with antioxidant properties, on HCl plus ethanol-induced gastric mucosal injury and on the healing of acetic acid-induced gastric ulcers in rats." | 3.70 | Anti-ulcer effects of antioxidants: effect of probucol. ( Ishihara, M; Ito, M; Suzuki, Y, 1998) |
"To evaluate the effects of teprenone on acute gastritis, its inhibitory effects on gastric mucosal damage were compared to that of gefarnate in taurocholate/hydrochloric acid-induced acute gastric mucosal lesions in rats." | 3.70 | [Protective effects of teprenone and gefarnate against taurocholate/hydrochloric acid-induced acute gastric mucosal lesions in rats]. ( Katoh, Y; Kawashima, H; Tanaka, M, 1998) |
"Effect of superimposed high frequency oscillatory ventilation on pulmonary gas exchange was investigated in seven anesthetized and paralyzed dogs with pulmonary edema induced by intrapulmonary injection of hydrochloric acid." | 3.68 | [Effect of superimposed high frequency oscillation on pulmonary edema induced by intrapulmonary injection of hydrochloric acid in dogs]. ( Sakai, T; Takaori, M; Yoshida, H, 1991) |
"Previous abdominal aortic aneurysm (AAA) animal modeling methodologies were either expensive or complicated." | 1.91 | A novel abdominal aortic aneurysm model produced by periarterial application of hydrochloric acid. ( Chang, X; Duan, C; Guo, W; Wei, R; Wu, Z; Xiong, J, 2023) |
"Based on our experiments, HCl-RFA in the liver appears to be as safe as NS-RFA while also resulting in larger ablation zones." | 1.48 | Safety and effect on ablation size of hydrochloric acid-perfused radiofrequency ablation in animal livers. ( Gao, F; Gu, YK; Huang, JH; Huang, SM; Huang, ZM; Jiang, XY; Liu, DX; Zhang, TQ, 2018) |
"Severe acute respiratory distress syndrome (ARDS) presents typically with an initializing event, followed by the need for mechanical ventilation." | 1.48 | Capturing the multifactorial nature of ARDS - "Two-hit" approach to model murine acute lung injury. ( Angulo, M; Blackburn, MR; Burns, N; Eltzschig, HK; Francis, D; Hoegl, S; Mills, TW; Osborne, CM; Vohwinkel, CU, 2018) |
"Objective As pulmonary inflammation stimulates TF expression and TF modulates immune responses, we aimed to elucidate its impact on ALI." | 1.46 | Myeloid but not epithelial tissue factor exerts protective anti-inflammatory effects in acid aspiration-induced acute lung injury. ( Assinger, A; Ay, C; Datler, H; Hell, L; Horvath, V; Jilma, B; Knapp, S; Kral-Pointner, JB; Mackman, N; Niederreiter, B; Schabbauer, G; Schmid, JA; Schrottmaier, WC, 2017) |
"A hallmark of acute respiratory distress syndrome (ARDS) is accumulation of protein-rich edema in the distal airspaces and its removal is critical for patient survival." | 1.46 | Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome. ( Burns, N; Edwards, MG; Eltzschig, HK; Hoffman, O; Vadász, I; Vohwinkel, CU, 2017) |
"Evans Blue (EB) dye was applied by injection of tail vein after mucosal damage to observe the neurogenic plasma extravasation dots in the skin of the rats." | 1.46 | Cutaneous neurogenic inflammation in the sensitized acupoints induced by gastric mucosal injury in rats. ( Bai, WZ; Cheng, B; He, W; Jing, XH; Shi, H; Su, YS; Wang, XY; Yu, XC; Zhu, B, 2017) |
"Aspiration-induced lung injury can decrease gas exchange and increase mortality." | 1.42 | Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats. ( Bergmann, R; Koch, T; Musch, G; Pietzsch, J; Richter, T, 2015) |
"Gastroesophageal reflux is a common disorder closely related to chronic airway diseases, such as chronic cough, asthma, chronic bronchitis, and chronic obstructive disease." | 1.40 | Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs. ( Cao, AL; Cheng, YM; Liu, CF; Sun, YS; Wang, HW; Wang, Y; Wu, DZ; Zhang, BB; Zheng, JP; Zhu, SL, 2014) |
"In a murine model of acute respiratory distress syndrome, lipid mediator metabololipidomics uncovered MaR1 generation in vivo in a temporally regulated manner." | 1.40 | Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective. ( Abdulnour, RE; Colas, RA; Colby, JK; Dalli, J; Krishnamoorthy, N; Levy, BD; Petasis, NA; Serhan, CN; Tan, SH; Timmons, JY, 2014) |
"Oral ulcers are relatively common and these lesions cause strong pain and discomfort." | 1.38 | Characterization of oral ulcer and pathological scar in nude mice model. ( Amiranashvili, I; Gogilashvili, Q; Imnadze, I; Sukhitashvili, N; Tabaghua, G, 2012) |
"Gastroesophageal reflux disease (GERD) has been linked to a number of extra-esophageal symptoms and disorders, primarily in the respiratory tract." | 1.36 | A novel external esophageal perfusion model for reflux-associated respiratory symptoms. ( Kang, J; Kong, L; Li, Q; Liu, X; Wang, J; Zhang, S; Zhong, Z, 2010) |
"Gastro-oesophageal reflux is frequent in chronic airway diseases and is considered a trigger for symptoms." | 1.36 | Tiotropium reduction of lung inflammation in a model of chronic gastro-oesophageal reflux. ( Advenier, C; Chen, H; Cui, Y; Devillier, P; Kuang, X; Wang, H; Xia, Z; Xu, Z; Zemoura, L; Zhu, L, 2010) |
" immediately after each dosing of 5-FU significantly reversed the delay in healing by 5-FU, and this effect was attenuated by the chemical ablation of capsaicin-sensitive afferent neurons." | 1.35 | Impairment by 5-fluorouracil of the healing of gastric lesions in rats: effect of lafutidine, a histamine H2 receptor antagonist, mediated by capsaicin-sensitive afferent neurons. ( Amagase, K; Hayashi, S; Komatsu, Y; Kotani, T; Murashima, Y; Nakagiri, A; Takeuchi, K, 2009) |
"Pretreatment with beraprost attenuated AGML and downregulated the expression of HNE and HO-1, while sensory denervation aggravated AGML and upregulated the expression of HNE and HO-1." | 1.35 | Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions. ( Ichinose, M; Ito, T; Kimura, H; Oka, M; Shimizu, Y; Tsuruo, Y; Ueda, K; Ueyama, T; Yoshida, K, 2008) |
" EDE had gastroprotective effect related to increase of glutathione bioavailability and stimulated higher levels of NO, H2O2 and TNF-alpha production." | 1.35 | Davilla elliptica and Davilla nitida: gastroprotective, anti-inflammatory immunomodulatory and anti-Helicobacter pylori action. ( Bauab, TM; Brito, AR; Carlos, IZ; Hiruma-Lima, CA; Kushima, H; Nishijima, CM; Rinaldo, D; Rodrigues, CM; Sassá, MF; Stasi, LC; Vilegas, W, 2009) |
"Lung inflammation was analyzed by quantifying cell influx, cytokine levels, and oxidized lipids." | 1.35 | Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo. ( Bauer, M; Binder, CJ; Dietl, W; Doninger, B; Haslinger, I; Knapp, S; Matt, U; Mesteri, I; Perkmann, T; Petzelbauer, P; Reingruber, S; Schabbauer, G; Warszawska, JM, 2009) |
"Acute lung injury (ALI) is a severe illness with excess mortality and no specific therapy." | 1.33 | Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury. ( Bonnans, C; Fredenburgh, LE; Fukunaga, K; Kohli, P; Levy, BD, 2005) |
"Gastroesophageal reflux is related to various laryngeal manifestations." | 1.33 | Effect of acid and pepsin on glottic wound healing: a simulated reflux model. ( Roh, JL; Yoon, YH, 2006) |
"Naloxone pretreatment abolished the effect of morphine, but was enable to block the inhibitory effect of nociceptin." | 1.32 | Nociceptin inhibits airway microvascular leakage induced by HCl intra-oesophageal instillation. ( Advenier, C; Bardou, M; Cui, YY; D'Agostino, B; Faisy, C; Naline, E; Rouget, C, 2004) |
"To quantify hyperalgesia, paw withdrawal latency to radiant heat (heat hyperalgesia) and withdrawal threshold to mechanical stimuli (mechanical hyperalgesia) were measured." | 1.31 | Unilateral intramuscular injections of acidic saline produce a bilateral, long-lasting hyperalgesia. ( Kalra, A; Moore, SA; Sluka, KA, 2001) |
"Cartilage necrosis is prominent during the early stages after laryngotracheoplasty." | 1.31 | Simulated reflux and laryngotracheal reconstruction: a rabbit model. ( Carron, JD; Derkay, CS; Greinwald, JH; Oberman, JP; Werner, AL, 2001) |
"To induce acute lung injury, hydrochloric acid was instilled into the tracheas of paralyzed sheep receiving controlled mechanical ventilation." | 1.31 | Nitric oxide inhalation increases alveolar gas exchange by decreasing deadspace volume. ( Banner, MJ; Burchfield, DJ; Davenport, PW; Jaeger, MJ; Skimming, JW; Spalding, HK, 2001) |
"The additional decrease in pulmonary edema with a tidal volume of 3 ml/kg is partly accounted for by greater protection of the alveolar epithelium." | 1.31 | Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs. ( Allen, L; Dobbs, L; Frank, JA; Gutierrez, JA; Jones, KD; Matthay, MA, 2002) |
"Gastro-oesophageal reflux is a common clinical disorder associated with a variety of respiratory symptoms, including chronic cough and exacerbation of asthma." | 1.31 | Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation. ( Advenier, C; Alt, XE; D'Agostino, B; Daoui, S; Gallelli, L; Rossi, F, 2002) |
"Furthermore, acidosis caused lung inflammation, as suggested by the increase in lung myeloperoxidase activity (282." | 1.30 | Acidosis stimulates nitric oxide production and lung damage in rats. ( Camporesi, EM; Caruso, JE; Hakim, TS; Hoffmann, SP; McGraw, DJ; Nandi, J; Oler, A; Pedoto, A; Tassiopoulos, AK, 1999) |
"Pretreatment with glycine significantly protected animals against stress-, indomethacin- and necrotizing agents induced gastric lesions." | 1.30 | Studies on the antisecretory, gastric anti-ulcer and cytoprotective properties of glycine. ( Al Moutaery, AR; Tariq, M, 1997) |
"The results show that at the site of aspiration pneumonia, anti-CD11b F(ab')2 did not inhibit neutrophil sequestration or edema formation, either with or without endotoxin pretreatment." | 1.30 | Role of CD11b in focal acid-induced pneumonia and contralateral lung injury in rats. ( Bree, M; Doerschuk, CM; Motosugi, H; Quinlan, WM, 1998) |
"Reflux esophagitis and hiatal hernia commonly coexist, yet a cause and effect relationship remains unclear." | 1.29 | Esophageal shortening induced by short-term intraluminal acid perfusion in opossum: a cause for hiatus hernia? ( Kolyn, DM; Paterson, WG, 1994) |
"Acute tracheal injury model (Mendelson Syndrome) were made." | 1.29 | [An aspiration pneumonia in acute airway damage model induced by HCl and/or LPS]. ( Fukuchi, Y; Higashimoto, Y; Ishida, K; Jo, C; Matsui, H; Matsuse, T; Nagase, T; Oka, T; Sudo, E; Teramoto, S, 1993) |
"The adult respiratory distress syndrome is a form of acute lung injury (ALI) that is frequently associated with systemic organ injury and often occurs in the setting of wide-spread inflammatory cell activation." | 1.29 | Acid aspiration-induced acute lung injury causes leukocyte-dependent systemic organ injury. ( Dorinsky, PM; Kindt, GC; Mizer, LA; Moore, SA; St John, RC; Weisbrode, SE, 1993) |
" In animals pretreated by anti-inflammatory drugs in toxic doses an earlier development of ulceration was observed by distention with acid." | 1.26 | Distention ulcer as a model for testing of drugs for ulcerogenic side effects. ( Szelenyi, I; Thiemer, K, 1978) |
"A severe respiratory acidosis resulted." | 1.25 | Ventilation and blood-gas studies during experimentally produced Mendelson's syndrome in the dog. ( Fabre, J; Francois, G; Gouin, F; Ohresser, P; Tournigand, T, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 31 (15.66) | 18.7374 |
1990's | 24 (12.12) | 18.2507 |
2000's | 63 (31.82) | 29.6817 |
2010's | 70 (35.35) | 24.3611 |
2020's | 10 (5.05) | 2.80 |
Authors | Studies |
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Zhang, Y | 3 |
Sun, L | 2 |
Lai, X | 1 |
Peng, X | 1 |
Wen, S | 1 |
Zhang, Z | 1 |
Xie, Y | 1 |
Li, Q | 2 |
Chen, R | 1 |
Zheng, X | 1 |
Zhang, K | 1 |
Sun, S | 1 |
Li, D | 1 |
Wei, R | 1 |
Chang, X | 1 |
Wu, Z | 1 |
Duan, C | 1 |
Xiong, J | 1 |
Guo, W | 1 |
Hendawy, H | 1 |
Metwally, E | 1 |
Elfadadny, A | 1 |
Yoshida, T | 1 |
Ma, D | 1 |
Shimada, K | 1 |
Hamabe, L | 1 |
Sasaki, K | 1 |
Tanaka, R | 1 |
Tavares, AH | 1 |
Colby, JK | 2 |
Levy, BD | 3 |
Abdulnour, RE | 2 |
Puri, G | 1 |
Naura, AS | 2 |
Cakir, E | 1 |
Cakir, U | 1 |
Tayman, C | 1 |
Turkmenoglu, TT | 1 |
Gonel, A | 1 |
Turan, IO | 1 |
Guillamat-Prats, R | 2 |
Camprubí-Rimblas, M | 1 |
Puig, F | 2 |
Herrero, R | 2 |
Tantinyà, N | 1 |
Serrano-Mollar, A | 2 |
Artigas, A | 2 |
Engel, M | 1 |
Nowacki, RME | 1 |
Jonker, EM | 1 |
Ophelders, D | 1 |
Nikiforou, M | 1 |
Kloosterboer, N | 1 |
Zimmermann, LJI | 1 |
van Waardenburg, DA | 1 |
Kramer, BW | 1 |
Boeing, T | 1 |
Mejía, JAA | 1 |
Ccana-Ccapatinta, GV | 1 |
Mariott, M | 1 |
Melo Vilhena de Andrade Fonseca Da Silva, RC | 1 |
de Souza, P | 1 |
Mariano, LNB | 1 |
Oliveira, GR | 1 |
da Rocha, IM | 1 |
da Costa, GA | 1 |
de Andrade, SF | 1 |
da Silva, LM | 1 |
Bastos, JK | 1 |
Jodłowski, PJ | 1 |
Kurowski, G | 1 |
Kuterasiński, Ł | 1 |
Sitarz, M | 1 |
Jeleń, P | 1 |
Jaśkowska, J | 1 |
Kołodziej, A | 1 |
Pajdak, A | 1 |
Majka, Z | 1 |
Boguszewska-Czubara, A | 1 |
Kim, JK | 1 |
Choi, E | 1 |
Hong, YH | 1 |
Kim, H | 1 |
Jang, YJ | 1 |
Lee, JS | 1 |
Choung, ES | 1 |
Woo, BY | 1 |
Hong, YD | 1 |
Lee, S | 1 |
Lee, BH | 1 |
Bach, TT | 1 |
Kim, JH | 3 |
Cho, JY | 3 |
Kral-Pointner, JB | 1 |
Schrottmaier, WC | 1 |
Horvath, V | 1 |
Datler, H | 1 |
Hell, L | 1 |
Ay, C | 1 |
Niederreiter, B | 1 |
Jilma, B | 1 |
Schmid, JA | 1 |
Assinger, A | 1 |
Mackman, N | 1 |
Knapp, S | 2 |
Schabbauer, G | 2 |
Yang, HJ | 1 |
Kim, MJ | 1 |
Kwon, DY | 1 |
Kang, ES | 1 |
Kang, S | 1 |
Park, S | 1 |
Tayeby, F | 1 |
Salman, AAA | 1 |
Kamran, S | 1 |
Khaing, SL | 1 |
Salehen, NB | 1 |
Mohan, GMAD | 1 |
Hamdi, A | 2 |
Majouli, K | 2 |
Abdelhamid, A | 2 |
Marzouk, B | 1 |
Belghith, H | 1 |
Chraief, I | 1 |
Bouraoui, A | 4 |
Marzouk, Z | 1 |
Heyden, YV | 1 |
Güzel, A | 1 |
Doğan, E | 1 |
Türkçü, G | 1 |
Kuyumcu, M | 1 |
Kaplan, İ | 1 |
Çelik, F | 1 |
Yıldırım, ZB | 1 |
Wang, X | 1 |
Chen, Q | 1 |
Tian, W | 1 |
Wang, J | 2 |
Cheng, L | 2 |
Lu, J | 1 |
Chen, M | 1 |
Pei, Y | 1 |
Li, C | 1 |
Chen, G | 1 |
Gu, N | 1 |
Kenani, A | 1 |
Zhang, TQ | 1 |
Huang, SM | 1 |
Gu, YK | 1 |
Gao, F | 1 |
Huang, ZM | 1 |
Jiang, XY | 1 |
Liu, DX | 1 |
Huang, JH | 1 |
Pourfathi, M | 1 |
Cereda, M | 1 |
Chatterjee, S | 1 |
Xin, Y | 1 |
Kadlecek, S | 1 |
Duncan, I | 1 |
Hamedani, H | 1 |
Siddiqui, S | 1 |
Profka, H | 1 |
Ehrich, J | 1 |
Ruppert, K | 1 |
Rizi, RR | 1 |
Hoegl, S | 1 |
Burns, N | 2 |
Angulo, M | 1 |
Francis, D | 1 |
Osborne, CM | 1 |
Mills, TW | 1 |
Blackburn, MR | 1 |
Eltzschig, HK | 2 |
Vohwinkel, CU | 2 |
Setzer, F | 1 |
Schmidt, B | 1 |
Hueter, L | 1 |
Schwarzkopf, K | 1 |
Sänger, J | 1 |
Schreiber, T | 1 |
Fletcher, JWA | 1 |
Williams, S | 1 |
Whitehouse, MR | 1 |
Gill, HS | 1 |
Preatoni, E | 1 |
Sahu, B | 1 |
Sandhir, R | 1 |
Qian, Y | 2 |
Zhang, J | 1 |
Fu, X | 1 |
Yi, R | 1 |
Sun, P | 3 |
Zou, M | 1 |
Long, X | 1 |
Zhao, X | 3 |
Jia, BY | 1 |
Xie, CE | 1 |
Wang, ZB | 1 |
Pei, WJ | 1 |
Li, XH | 1 |
Shi, L | 1 |
Liu, JL | 1 |
Han, YF | 1 |
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Tigyi, A | 1 |
Tóth, G | 1 |
Zsoldos, T | 1 |
Mózsik, G | 1 |
Stothert, JC | 1 |
Basadre, JO | 1 |
Herndon, D | 1 |
Traber, L | 1 |
Traber, D | 1 |
Griffeth, JK | 1 |
Gallagher, TJ | 1 |
Packer, DL | 1 |
Lamm, WJ | 1 |
Luchtel, D | 1 |
Albert, RK | 1 |
Fisher, DJ | 1 |
Dreyer, WJ | 1 |
Tate, C | 1 |
Michael, L | 1 |
Smith, EO | 1 |
Entman, M | 1 |
Fisher, RA | 1 |
Eckhauser, ML | 1 |
Radivoyevitch, M | 1 |
Ragins, H | 1 |
Levenson, SM | 1 |
Signer, R | 1 |
Stamford, W | 1 |
Seifter, E | 1 |
Cibis, GW | 1 |
Kolder, H | 1 |
Vojtísek, V | 2 |
Jelínek, V | 2 |
Hradil, F | 1 |
Dudley, WR | 1 |
Marshall, BE | 1 |
Safaie-Shirazi, S | 1 |
DenBesten, L | 1 |
Hamza, KN | 1 |
Russell, CD | 1 |
Illickal, MM | 1 |
Maloney, JV | 1 |
Roeher, HD | 1 |
DeLand, EC | 1 |
Chlumská, A | 1 |
Rubin, S | 1 |
Davidson, JT | 1 |
Eyal, Z | 1 |
Veress, B | 2 |
Kádár, A | 2 |
Jellinek, H | 2 |
Aruin, LI | 1 |
Vaĭnshteĭn, TIa | 1 |
Zhuk, EA | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Intravesical Botulinum Toxin A Injection in Treatment of Interstitial Cystitis Refractory to Conventional Treatment - A Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial[NCT01969773] | Phase 2 | 60 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
Hemodynamics and Extravascular Lung Water in Acute Lung Injury: A Prospective Randomized Controlled Multicentered Trial of Goal Directed Treatment of EVLW Versus Standard Management for the Treatment of Acute Lung Injury[NCT00624650] | Phase 2 | 33 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
198 other studies available for hydrochloric acid and Disease Models, Animal
Article | Year |
---|---|
Gastroprotective effects of extract of Jasminum grandiflorum L. flower in HCl/EtOH-induced gastric mucosal ulceration mice.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Apoptosis Regulatory Proteins; D | 2021 |
A novel abdominal aortic aneurysm model produced by periarterial application of hydrochloric acid.
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Hydrochloric Acid; Ma | 2023 |
Cultured versus freshly isolated adipose-derived stem cells in improvement of the histopathological outcomes in HCL-induced cystitis in a rat model.
Topics: Adipose Tissue; Animals; Cells, Cultured; Cystitis, Interstitial; Disease Models, Animal; Female; Fi | 2022 |
A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation.
Topics: Acute Lung Injury; Animals; Bronchi; Disease Models, Animal; Hydrochloric Acid; Leukocytes; Lung; Ma | 2019 |
Critical role of mitochondrial oxidative stress in acid aspiration induced ALI in mice.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Gene Ex | 2020 |
Favorable Effects of Astaxanthin on Brain Damage due to Ischemia- Reperfusion Injury.
Topics: Animals; Brain; Disease Models, Animal; Hydrochloric Acid; Injections, Intraperitoneal; Male; Neurop | 2020 |
Alveolar Type II Cells or Mesenchymal Stem Cells: Comparison of Two Different Cell Therapies for the Treatment of Acute Lung Injury in Rats.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Bone Marrow Cells; Cells, Cultured; Cytokines | 2020 |
A comparison of four different models of acute respiratory distress syndrome in sheep.
Topics: Albumins; Animals; Biomarkers; Bronchoalveolar Lavage; Disease Models, Animal; Female; Hydrochloric | 2020 |
The gastroprotective effect of red propolis extract from Northeastern Brazil and the role of its isolated compounds.
Topics: Animals; Anti-Ulcer Agents; Brazil; Disease Models, Animal; Ethanol; Gastric Acid; Gastric Mucins; G | 2021 |
Cracking the Chloroquine Conundrum: The Application of Defective UiO-66 Metal-Organic Framework Materials to Prevent the Onset of Heart Defects-In Vivo and In Vitro.
Topics: Animals; Chloroquine; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Heart Diseases | 2021 |
Syk/NF-κB-targeted anti-inflammatory activity of Melicope accedens (Blume) T.G. Hartley methanol extract.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Ethanol; | 2021 |
Myeloid but not epithelial tissue factor exerts protective anti-inflammatory effects in acid aspiration-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Antithrombin III; Blood Coagulation; Cells, Cultured; Chemotaxis, Leukoc | 2017 |
Gastroprotective actions of Taraxacum coreanum Nakai water extracts in ethanol-induced rat models of acute and chronic gastritis.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Ethanol; Flavonoids; Gastric Muc | 2017 |
Ulcer Prevention Effect Of 3,4,5-Tihydroxy-N0-[(2-Methyl-1H-Indol-3yl)Methylidene]Benzohydrazide In HCl/Ethanol-Induced Gastric Mucosal Damage In Rats.
Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Disease Models, Animal; Ethanol; Gallic Acid; Gas | 2017 |
Pharmacological activities of the organic extracts and fatty acid composition of the petroleum ether extract from Haplophyllum tuberculatum leaves.
Topics: Acetic Acid; Alkanes; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; | 2018 |
Dexmedetomidine and Magnesium Sulfate: A Good Combination Treatment for Acute Lung Injury?
Topics: Acute Lung Injury; Administration, Intravenous; Animals; Anti-Inflammatory Agents; Antioxidants; Dex | 2019 |
Measurement of In Vitro Single Cell Temperature by Novel Thermocouple Nanoprobe in Acute Lung Injury Models.
Topics: Acute Lung Injury; Adenosine Triphosphate; Animals; Cell Line; Cobalt; Disease Models, Animal; Energ | 2017 |
Anti-inflammatory activity and gastroprotective effect of Hertia cheirifolia L. roots extract.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Asteraceae; Carrageenan; Disease Models, Anima | 2018 |
Safety and effect on ablation size of hydrochloric acid-perfused radiofrequency ablation in animal livers.
Topics: Animals; Disease Models, Animal; Hydrochloric Acid; Liver; Perfusion; Rabbits; Radiofrequency Ablati | 2018 |
Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach.
Topics: Acute Lung Injury; Animals; Biomarkers; Carbon Isotopes; Disease Models, Animal; Gene Expression; Hu | 2018 |
Capturing the multifactorial nature of ARDS - "Two-hit" approach to model murine acute lung injury.
Topics: Animals; Disease Models, Animal; Female; Hydrochloric Acid; Lipopolysaccharides; Male; Mice; Mice, I | 2018 |
Characterization of the seven-day course of pulmonary response following unilateral lung acid injury in rats.
Topics: Acute Lung Injury; Animals; Arterial Pressure; Bronchoalveolar Lavage Fluid; Case-Control Studies; C | 2018 |
Juvenile bovine bone is an appropriate surrogate for normal and reduced density human bone in biomechanical testing: a validation study.
Topics: Age Factors; Animals; Biomechanical Phenomena; Bone Demineralization Technique; Bone Density; Cattle | 2018 |
Two hit induced acute lung injury impairs cognitive function in mice: A potential model to study cross talk between lung and brain.
Topics: Acute Lung Injury; Animals; Blood-Brain Barrier; Brain; Cognition; Cognitive Dysfunction; Disease Mo | 2018 |
Preventive Effect of Raw Liubao Tea Polyphenols on Mouse Gastric Injuries Induced by HCl/Ethanol via Anti-Oxidative Stress.
Topics: Animals; Antioxidants; Biomarkers; Biopsy; Cytokines; Disease Models, Animal; Ethanol; Gastric Juice | 2018 |
The effect of Heweijiangni-decoction on esophageal morphology in a rat model of OVA-induced visceral hypersensitivity followed by acid exposure.
Topics: Animals; Desmosomes; Disease Models, Animal; Drugs, Chinese Herbal; Esophagus; Extracellular Space; | 2019 |
Pulmonary blood flow increases in damaged regions directly after acid aspiration in rats.
Topics: Animals; Disease Models, Animal; Gallium Radioisotopes; Hydrochloric Acid; Lung; Positron-Emission T | 2013 |
Aerosolized KL4 surfactant improves short-term survival and gas exchange in spontaneously breathing newborn pigs with hydrochloric acid-induced acute lung injury.
Topics: Acute Lung Injury; Administration, Inhalation; Aerosols; Animals; Animals, Newborn; Continuous Posit | 2014 |
Reduction of oxidative stress may play a role in the anti-inflammatory effect of the novel herbal formulation in a rat model of hydrochloric acid-induced cystitis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cystitis; Disease Models, Animal; Female; Hydrochlo | 2015 |
The effects of exogenous surfactant administration on ventilation-induced inflammation in mouse models of lung injury.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eicosan | 2013 |
Apolipoprotein E-deficient mice are susceptible to the development of acute lung injury.
Topics: Acute Lung Injury; Animals; Apolipoproteins E; Disease Models, Animal; Genetic Predisposition to Dis | 2014 |
Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs.
Topics: Airway Remodeling; Animals; Bronchial Hyperreactivity; Calcium Channels, L-Type; Disease Models, Ani | 2014 |
Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: An observational study in rats.
Topics: Animals; Disease Models, Animal; Hydrochloric Acid; Lung; Lung Injury; Male; Positron-Emission Tomog | 2015 |
Pharmacological evaluation of the semi-purified fractions from the soft coral Eunicella singularis and isolation of pure compounds.
Topics: Animals; Anthozoa; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; Disease Models, Animal; | 2014 |
The potential of microfluidic lung epithelial wounding: towards in vivo-like alveolar microinjuries.
Topics: Animals; Disease Models, Animal; Equipment Design; Equipment Failure Analysis; Feasibility Studies; | 2014 |
Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective.
Topics: Animals; Arachidonate 12-Lipoxygenase; Blood Platelets; Bronchoalveolar Lavage Fluid; Cell Hypoxia; | 2014 |
Physico-chemical characterization and pharmacological evaluation of sulfated polysaccharides from three species of Mediterranean brown algae of the genus Cystoseira.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Disease Models, Animal; Dose-Response | 2015 |
Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats.
Topics: Animals; Disease Models, Animal; Gallium Radioisotopes; Hydrochloric Acid; Lung Injury; Male; Micros | 2015 |
Intravesical treatment with cis-urocanic acid improves bladder function in rat model of acute bladder inflammation.
Topics: Administration, Intravesical; Animals; Cystitis; Disease Models, Animal; Female; Hyaluronic Acid; Hy | 2016 |
Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury.
Topics: Acute Lung Injury; Animals; Bone Marrow Transplantation; Calcium Signaling; Capillary Permeability; | 2016 |
Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Blood Cell Count; Cytokines; Disease Models, A | 2015 |
Investigation of Antiulcer and Antioxidant Activity of Juniperus phoenicea L. (1753) Essential Oil in an Experimental Rat Model.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Bicyclic Monoterpenes; Catalase; Disease Models, Animal; E | 2015 |
Establishment of hydrochloric acid/lipopolysaccharide-induced pelvic inflammatory disease model.
Topics: Animals; Blotting, Western; Cytokines; Disease Models, Animal; Female; Humans; Hydrochloric Acid; In | 2016 |
Lactobacillus fermentum Suo Attenuates HCl/Ethanol Induced Gastric Injury in Mice through Its Antioxidant Effects.
Topics: Animals; Antioxidants; Cytokines; Disease Models, Animal; Ethanol; Gastric Juice; Gastric Mucosa; Ga | 2016 |
Gastroprotective effects of new diterpenoid derivatives from Azorella cuatrecasasii Mathias & Constance obtained using a β-cyclodextrin complex with microbial and chemical transformations.
Topics: Alcohols; Animals; Anti-Ulcer Agents; Apiaceae; beta-Cyclodextrins; Disease Models, Animal; Diterpen | 2016 |
PDK1 in NF-κB signaling is a target of Xanthium strumarium methanolic extract-mediated anti-inflammatory activities.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; D | 2016 |
A new experimental model of acid- and endotoxin-induced acute lung injury in rats.
Topics: Acute Lung Injury; Animals; Apoptosis; Disease Models, Animal; Hydrochloric Acid; Lipopolysaccharide | 2016 |
Preventive effect of Gardenia jasminoides on HCl/ethanol induced gastric injury in mice.
Topics: Animals; Antioxidants; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Gardenia; Hydrochlori | 2017 |
A Zinc Morpholine Complex Prevents HCl/Ethanol-Induced Gastric Ulcers in a Rat Model.
Topics: Animals; Cell Line; Disease Models, Animal; DNA Damage; Ethanol; Humans; Hydrochloric Acid; Hydrogen | 2016 |
A knockin mouse model for human ATP4aR703C mutation identified in familial gastric neuroendocrine tumors recapitulates the premalignant condition of the human disease and suggests new therapeutic strategies.
Topics: Anemia; Animals; Disease Models, Animal; Gastric Acid; Gastrins; Gene Knock-In Techniques; H(+)-K(+) | 2016 |
Gastroprotective activity of the resin from Virola oleifera.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Benzothiazoles; Chromatography, Thin Layer; Disease Models | 2017 |
Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome.
Topics: A549 Cells; Animals; Disease Models, Animal; ELAV-Like Protein 1; Glycogen Synthase Kinase 3 beta; H | 2017 |
Cutaneous neurogenic inflammation in the sensitized acupoints induced by gastric mucosal injury in rats.
Topics: Acupuncture Points; Animals; Antibodies; Biomarkers; Coloring Agents; Disease Models, Animal; Evans | 2017 |
Impairment by 5-fluorouracil of the healing of gastric lesions in rats: effect of lafutidine, a histamine H2 receptor antagonist, mediated by capsaicin-sensitive afferent neurons.
Topics: Acetamides; Animals; Antimetabolites, Antineoplastic; Capsaicin; Cell Line; Cell Movement; Cell Prol | 2009 |
Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions.
Topics: Adaptation, Physiological; Aldehydes; Animals; Capsaicin; Cytoprotection; Denervation; Disease Model | 2008 |
Alterations in N-methyl-D-aspartate receptor subunits in primary sensory neurons following acid-induced esophagitis in cats.
Topics: Animals; Blotting, Western; Cats; Disease Models, Animal; Eosinophil Peroxidase; Esophagitis; Esopha | 2009 |
Hemodynamic effects of PEEP in a porcine model of HCl-induced mild acute lung injury.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Echocardiography, Transesophageal; Hemodynamics; | 2009 |
Hydrochloric acid aspiration increases right ventricular systolic pressure in rats.
Topics: Anesthesia, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Endothe | 2009 |
Bladder hyperactivity and increased excitability of bladder afferent neurons associated with reduced expression of Kv1.4 alpha-subunit in rats with cystitis.
Topics: Animals; Capsaicin; Cystitis; Disease Models, Animal; Female; Hydrochloric Acid; Kv1.4 Potassium Cha | 2009 |
Davilla elliptica and Davilla nitida: gastroprotective, anti-inflammatory immunomodulatory and anti-Helicobacter pylori action.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 2009 |
Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Fibrin Fibrinogen Degradation Products; Hydrochl | 2009 |
Tiotropium reduction of lung inflammation in a model of chronic gastro-oesophageal reflux.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Atropine; Biopsy; Bronchoalveolar Lavage Fluid; Br | 2010 |
Anti-ulcer role of herbomineral Siddha drug - Thamira parpam on experimentally induced gastric mucosal damage in rats.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Body Weight; Cytoprotection; Disease Models, Anim | 2010 |
A novel external esophageal perfusion model for reflux-associated respiratory symptoms.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Feasi | 2010 |
Simulated reflux decreases vocal fold epithelial barrier resistance.
Topics: Animals; Disease Models, Animal; Electric Impedance; Gastroesophageal Reflux; Gastrointestinal Agent | 2010 |
Divergent effects of irritants on the gastric mucosa in rats during various stages after bile duct ligation.
Topics: Animals; Cholestasis, Extrahepatic; Common Bile Duct; Dinoprostone; Disease Models, Animal; Disease | 2010 |
Protective effects of a gastrointestinal agent containing Korean red ginseng on gastric ulcer models in mice.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Ga | 2010 |
Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis.
Topics: Adenosine Triphosphate; Animals; Benzhydryl Compounds; Benzofurans; Cresols; Cystitis; Disease Model | 2010 |
Gastroprotective effect and cytotoxicity of labdeneamides with amino acids.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Amides; Amino Acids; Animals; Anti-Ulcer Ag | 2011 |
Stable mixed acidemia in anesthetized pigs--a model for research on biocompatibility of hemofilters under a deteriorated acid-base balance.
Topics: Acidosis; Animals; Disease Models, Animal; Hemofiltration; Hydrochloric Acid; Lactic Acid; Male; Mat | 2011 |
Gastroprotective activity of Zanthoxylum rhoifolium Lam. in animal models.
Topics: Animals; Anti-Ulcer Agents; Catalase; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Eth | 2011 |
Antiulcerogenic activity of the essential oil of Hyptis martiusii Benth. (Lamiaceae).
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gas C | 2011 |
Time-dependent changes in bladder function and plantar sensitivity in a rat model of fibromyalgia syndrome induced by hydrochloric acid injection into the gluteus.
Topics: Anesthetics, Local; Animals; Case-Control Studies; Chronic Pain; Disease Models, Animal; Female; Fib | 2012 |
Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Cyclic AMP Response Element-Binding Protein | 2011 |
Protective effect of Polyalthia longifolia var. pendula leaves on ethanol and ethanol/HCl induced ulcer in rats and its antimicrobial potency.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Disease Models, Animal; Ethanol; Fe | 2011 |
Resolution of acute lung injury and inflammation: a translational mouse model.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hydroch | 2012 |
Intravesical chondroitin sulfate inhibits recruitment of inflammatory cells in an acute acid damage "leaky bladder" model of cystitis.
Topics: Animals; Burns, Chemical; Chemotaxis, Leukocyte; Chondroitin Sulfates; Cystitis; Disease Models, Ani | 2012 |
Experimental model of smoking and simulation of reflux with acid and pepsin in rats.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Disease Models, Animal; Gastric Mucosa; Gastroesophagea | 2012 |
Time course of metabolic activity and cellular infiltration in a murine model of acid-induced lung injury.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Cell Proliferation; Disease Models, Animal; Female; | 2012 |
Gastric cytoprotection and honey intake in albino rats.
Topics: Albinism; Animals; Anti-Ulcer Agents; Cytoprotection; Disease Models, Animal; Gastric Mucosa; Honey; | 2011 |
Gastro-protective effect of crude hexane leaf extract of Sesamum indicum in rabbits.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cytoprotection; Disease Models, Animal; Dose-Response Relati | 2011 |
Antiulcer principle from Zingiber montanum.
Topics: Animals; Anti-Ulcer Agents; Chromatography; Cytoprotection; Disease Models, Animal; Dose-Response Re | 2012 |
Modified yukmijihwangtang suppresses the production of proinflammatory cytokines in the intravesical hydrochloric acid-induced cystitis rat model via the NF-κB pathway.
Topics: Administration, Intravesical; Animals; Cystitis; Cytokines; Disease Models, Animal; Drugs, Chinese H | 2012 |
Platelets induce endothelial tissue factor expression in a mouse model of acid-induced lung injury.
Topics: Acute Lung Injury; Animals; Antigens, CD; Blood Coagulation; Blood Platelets; Cadherins; Disease Mod | 2012 |
Effects of intravesical dexpanthenol use on lipid peroxidation and bladder histology in a chemical cystitis animal model.
Topics: Administration, Intravesical; Animals; Cystitis, Interstitial; Disease Models, Animal; Female; Hydro | 2012 |
Progress in modelling acute lung injury in a pre-clinical mouse model.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Hydrochloric Acid; Male; Pneumonia; Translationa | 2012 |
Characterization of oral ulcer and pathological scar in nude mice model.
Topics: Animals; Cicatrix; Disease Models, Animal; Fibrosis; Humans; Hydrochloric Acid; Immunohistochemistry | 2012 |
Acid-induced acute lung injury in mice is associated with P44/42 and c-Jun N-terminal kinase activation and requires the function of tumor necrosis factor α receptor I.
Topics: Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage; Caspase 3; Disease Models, Animal; En | 2012 |
Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation.
Topics: Animals; Asthma; Capillary Permeability; Disease Models, Animal; Esophagus; Female; Gastroesophageal | 2002 |
Role of acid back-diffusion, glutathione, oxyradical, and histamine in antral hemorrhagic ulcer in rats: the protective effect of lysozyme chloride and antioxidants.
Topics: Animals; Antioxidants; Diffusion; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric | 2002 |
Effects of Anethum graveolens L. seed extracts on experimental gastric irritation models in mice.
Topics: Anethum graveolens; Animals; Anti-Ulcer Agents; Disease Models, Animal; Gastric Acid; Hydrochloric A | 2002 |
Botulinum toxin type A may improve bladder function in a rat chemical cystitis model.
Topics: Animals; Botulinum Toxins, Type A; Chronic Disease; Cystitis; Disease Models, Animal; Female; Hydroc | 2003 |
Real-time visualization of partial liquid ventilation in a model of acute lung injury.
Topics: Acute Disease; Albumins; Animals; Blood Pressure; Computer Systems; Disease Models, Animal; Heart Ra | 2003 |
Evaluation of the antiulcerogenic activity of violacein and its modulation by the inclusion complexation with beta-cyclodextrin.
Topics: Animals; Anti-Ulcer Agents; Cells, Cultured; Chemistry, Pharmaceutical; Cimetidine; Cyclodextrins; D | 2003 |
Intravascular infusion of acid promotes intrapulmonary inducible nitric oxide synthase activity and impairs blood oxygenation in rats.
Topics: Acidosis; Animals; Blotting, Western; Breath Tests; Disease Models, Animal; Enzyme-Linked Immunosorb | 2003 |
c-Fos immunoreactivity in the brain after esophageal acid stimulation.
Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Gastroesophageal Reflux; Hydrochloric Acid; Immu | 2003 |
Gastroprotective and anti-inflammatory effects of resin from Protium heptaphyllum in mice and rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Brazil; Burseraceae; Capillary Pe | 2004 |
Prevention of experimentally-induced gastric ulcers in rats by an ethanolic extract of "Parsley" Petroselinum crispum.
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Ethanol; Gastric Mucosa; Hydrochloric Acid; Hypo | 2003 |
Activation of the STAT pathway in acute lung injury.
Topics: Acute Disease; Animals; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Hydrochloric | 2004 |
Surfactant lavage with lidocaine improves pulmonary function in piglets after HCl-induced acute lung injury.
Topics: Adjuvants, Immunologic; Animals; Bronchoalveolar Lavage; Disease Models, Animal; Drug Therapy, Combi | 2004 |
Nociceptin inhibits airway microvascular leakage induced by HCl intra-oesophageal instillation.
Topics: Animals; Benzimidazoles; Bronchi; Capillary Permeability; Disease Models, Animal; Gastroesophageal R | 2004 |
Accuracy of the double indicator method for measurement of extravascular lung water depends on the type of acute lung injury.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Extravascular Lung Water; Female; Hemodynamic | 2004 |
Effects of nitric oxide synthase inhibitor on acid aspiration-induced lung injury in rats.
Topics: Amidines; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Enzyme Inhibito | 2005 |
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions.
Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge | 2005 |
Lipid compositions of human gastric fluid and epithelium: the role of sulfated lipids in gastric cytoprotection.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anticarcinogenic Agents; Cholesterol Esters; Chromatography | 2005 |
Gastroprotective activity of a new semi-synthetic solidagenone derivative in mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Animals; Anti-Ulcer Agents; Cell Line | 2005 |
Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury.
Topics: Animals; Base Sequence; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygena | 2005 |
[Prophylactic effect of ambroxol on acute hydrochloric acid aspiration - induced lung injury].
Topics: Acute Lung Injury; Ambroxol; Animals; Disease Models, Animal; Expectorants; Female; Hydrochloric Aci | 2005 |
Low positive end-expiratory pressure does not exacerbate nebulized-acid lung injury in dogs.
Topics: Animals; Disease Models, Animal; Dogs; Female; Hydrochloric Acid; Male; Nebulizers and Vaporizers; P | 2005 |
In vitro model of acute esophagitis in the cat.
Topics: Acute Disease; Animals; Cats; Cell Survival; Disease Models, Animal; Esophagitis; Hydrochloric Acid; | 2005 |
Inhibition of acid-induced lung injury by hyperosmolar sucrose in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cell Count; Disease Models, Animal; D | 2005 |
Role of bile acids, prostaglandins and COX inhibitors in chronic esophagitis in a mouse model.
Topics: Animals; Bile Acids and Salts; Chronic Disease; Cyclooxygenase Inhibitors; Dinoprostone; Disease Mod | 2006 |
[Comparison of single-indicator thermodilution versus gravimetric measurement in determination of extra-vascular lung water in dogs with acute respiratory distress syndrome].
Topics: Animals; Disease Models, Animal; Dogs; Extravascular Lung Water; Female; Hydrochloric Acid; Male; Ol | 2006 |
[Effects of different modes of artificial ventilation on lung injury in dog model of acute respiratory distress syndrome].
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Dogs; Hydrochloric Acid; Lung Diseases; | 2006 |
Comparison of systemic and local effects of nitric acid and hydrochloric acid: an experimental study in a rat model.
Topics: Administration, Oral; Animals; Burns, Chemical; Calcium; Disease Models, Animal; Esophagus; Hydrochl | 2006 |
Effect of acid and pepsin on glottic wound healing: a simulated reflux model.
Topics: Animals; Disease Models, Animal; Gastroesophageal Reflux; Glottis; Hydrochloric Acid; Male; Pepsin A | 2006 |
Gastroprotective activity and cytotoxic effect of cyperenoic acid derivatives.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Cell Line; Cell Survival; Disease Models, Animal; | 2006 |
[Effect of lung stress index on titration of positive end-expiratory pressure at post-recruitment in three canine acute respiratory distress syndrome models].
Topics: Animals; Disease Models, Animal; Dogs; Female; Hydrochloric Acid; Lung; Lung Compliance; Male; Oleic | 2006 |
The response to recruitment worsens with progression of lung injury and fibrin accumulation in a mouse model of acid aspiration.
Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Disease Progression; Fema | 2007 |
Alterations in the brain-gut axis underlying visceral chemosensitivity in Nippostrongylus brasiliensis-infected mice.
Topics: Adjuvants, Immunologic; Animals; Brain; Cholera Toxin; Disease Models, Animal; Female; Ganglia, Spin | 2007 |
Gastroprotective effect and cytotoxicity of labdenamides.
Topics: Animals; Anti-Ulcer Agents; Cells, Cultured; Disease Models, Animal; Diterpenes; Dose-Response Relat | 2007 |
Evaluation of Tectona grandis leaves for wound healing activity.
Topics: Administration, Oral; Administration, Topical; Aloe; Animals; Burns; Chemistry, Pharmaceutical; Derm | 2007 |
Cannabinoid CB(2) receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux.
Topics: Airway Obstruction; Animals; Benzoxazines; Bronchi; Bronchoconstriction; Camphanes; Cannabinoids; Ca | 2007 |
Airway responses to esophageal acidification.
Topics: Airway Resistance; Animals; Bronchi; Cats; Disease Models, Animal; Esophagus; Female; Gastroesophage | 2008 |
Laryngeal stimulation by an acid solution in the pre-term lamb.
Topics: Aging; Animals; Animals, Newborn; Citric Acid; Disease Models, Animal; Gastroesophageal Reflux; Hydr | 2008 |
Effects of PEEP levels following repeated recruitment maneuvers on ventilator-induced lung injury.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cytokines; Disease Models, Animal; Hydrochloric Acid; L | 2008 |
Effects of independent lung ventilation and lateral position on cytokine markers of inflammation after unilateral lung acid injury in dogs.
Topics: Animals; Bronchoalveolar Lavage; Disease Models, Animal; Dogs; Hydrochloric Acid; Interleukin-10; In | 2008 |
Lung injury and recovery in a murine model of unilateral acid aspiration: functional, biochemical, and morphologic characterization.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Female; Fibrosis; Hydrochloric Acid; Instillati | 2008 |
Secondary hypocapnia fails to protect "whole body" intracellular pH during chronic HCl-acidosis in the dog.
Topics: Acidosis; Animals; Bicarbonates; Body Fluids; Body Water; Body Weight; Carbon Dioxide; Chlorides; Di | 1983 |
Hypophosphaturia impairs the renal defense against metabolic acidosis.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Bicarbonates; Chlorides; Creatinine; Disease Models, Anima | 1984 |
[Development of lung edema following endotracheal instillation of hydrochloric acid (aspiration pneumonitis model)].
Topics: Animals; Capillary Permeability; Disease Models, Animal; Dogs; Hydrochloric Acid; Pneumonia, Aspirat | 1984 |
Ethanol-induced mucosal injury in rabbit oesophagus.
Topics: Animals; Bile Acids and Salts; Carbon Radioisotopes; Disease Models, Animal; Erythritol; Esophagitis | 1983 |
Aspiration pneumonitis. Correlation of experimental models with clinical disease.
Topics: Animals; Disease Models, Animal; Dogs; Gastric Acid; Humans; Hydrochloric Acid; Hydrogen-Ion Concent | 1982 |
Reduction of gastric stress ulcers by intraduodenal infusion of liquids--observations in a rat model.
Topics: Animals; Disease Models, Animal; Duodenum; Hydrochloric Acid; Infusions, Parenteral; Male; Rats; Res | 1980 |
Effect of acute administration of fish oil (omega-3 marine triglyceride) on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Ethanol; Female; Fish Oils; Gastric Aci | 1995 |
Aspiration-induced lung injury: role of complement.
Topics: Animals; Capillary Permeability; Complement Activation; Complement System Proteins; Disease Models, | 1995 |
[Effect of acid aspiration on right lymph duct lymph flow and prostaglandin metabolites in dogs].
Topics: Anesthesia, Intravenous; Animals; Capillary Permeability; Disease Models, Animal; Dogs; Hydrochloric | 1995 |
Esophageal shortening induced by short-term intraluminal acid perfusion in opossum: a cause for hiatus hernia?
Topics: Animals; Atropine; Constriction, Pathologic; Disease Models, Animal; Epithelium; Esophagus; Female; | 1994 |
[Diffuse aspiration bronchiolitis (DAB) produced in animals by repeated HCl microaspiration].
Topics: Animals; Bronchiolitis; Disease Models, Animal; Hydrochloric Acid; Pneumonia, Aspiration; Rats; Rats | 1994 |
[An aspiration pneumonia in acute airway damage model induced by HCl and/or LPS].
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydrochloric Acid; Lip | 1993 |
Sucralfate does not reduce the risk of acid aspiration pneumonitis.
Topics: Airway Resistance; Animals; Digestive System; Disease Models, Animal; Drug Evaluation, Preclinical; | 1993 |
Acid aspiration-induced acute lung injury causes leukocyte-dependent systemic organ injury.
Topics: Animals; Capillary Permeability; Cats; Cell Adhesion; Disease Models, Animal; Hydrochloric Acid; Ile | 1993 |
Acid-stimulated duodenal bicarbonate secretion involves a CFTR-mediated transport pathway in mice.
Topics: Animals; Bicarbonates; Biological Transport, Active; Cystic Fibrosis; Cystic Fibrosis Transmembrane | 1997 |
Studies on the antisecretory, gastric anti-ulcer and cytoprotective properties of glycine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Caustics; Disease Models, Anima | 1997 |
Role of CD11b in focal acid-induced pneumonia and contralateral lung injury in rats.
Topics: Animals; CD18 Antigens; Cell Adhesion; Cell Movement; Disease Models, Animal; Endotoxins; Hydrochlor | 1998 |
Role of mast cell-derived mediators in acid-induced shortening of the esophagus.
Topics: Animals; Bronchodilator Agents; Constriction, Pathologic; Cromolyn Sodium; Disease Models, Animal; E | 1998 |
A comparison among animal models of acute lung injury.
Topics: Animals; Disease Models, Animal; Endotoxins; Escherichia coli; Hemodynamics; Hydrochloric Acid; Olei | 1998 |
Anti-ulcer effects of antioxidants: effect of probucol.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; D | 1998 |
Experimental esophagitis induced by acid and pepsin in rabbits mimicking human reflux esophagitis.
Topics: Acute Disease; Animals; Cell Division; Chronic Disease; Disease Models, Animal; Esophagitis, Peptic; | 1999 |
Nitric oxide production after acute, unilateral hydrochloric acid-induced lung injury in a canine model.
Topics: Animals; Breath Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dogs; Hemodynamics; Hum | 1998 |
Acidosis stimulates nitric oxide production and lung damage in rats.
Topics: Acidosis; Animals; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Dose-Response Relatio | 1999 |
N-phosphonoalkyl-5-aminomethylquinoxaline-2,3-diones: in vivo active AMPA and NMDA(glycine) antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Disease Models, Anim | 1999 |
[Protective effects of teprenone and gefarnate against taurocholate/hydrochloric acid-induced acute gastric mucosal lesions in rats].
Topics: Acute Disease; Animals; Anti-Ulcer Agents; Disease Models, Animal; Diterpenes; Dose-Response Relatio | 1998 |
Partial liquid ventilation decreases serum tumor necrosis factor-alpha concentrations in a rat acid aspiration lung injury model.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Causality; Disease Models, Animal; Drug Evaluation, Pre | 2000 |
The role of pH and osmolarity in evoking the acetic acid-induced wiping response in a model of nociception in frogs.
Topics: Acetic Acid; Animals; Behavior, Animal; Buffers; Disease Models, Animal; Epidermis; Formates; Hydroc | 2000 |
Isolation of the antiulcer compound in essential oil from the leaves of Cryptomeria japonica.
Topics: Acetaldehyde; Animals; Anti-Ulcer Agents; Aspirin; Cycadopsida; Disease Models, Animal; Gastric Juic | 2000 |
[Pretreatment of acid-induced lung injury with specific neutrophil elastase inhibitor ONO-5046 did not exasperate the subsequent bacterial lung infection by Pseudomonas aeruginosa].
Topics: Animals; Disease Models, Animal; Glycine; Hydrochloric Acid; Leukocyte Elastase; Male; Pneumonia, As | 2000 |
Unilateral intramuscular injections of acidic saline produce a bilateral, long-lasting hyperalgesia.
Topics: Animals; Behavior, Animal; Body Weight; Coloring Agents; Disease Models, Animal; Drug Combinations; | 2001 |
Esophagitis-related esophageal shortening in opossum is associated with longitudinal muscle hyperresponsiveness.
Topics: Animals; Deglutition; Disease Models, Animal; Epithelial Cells; Esophageal Motility Disorders; Esoph | 2001 |
Simulated reflux and laryngotracheal reconstruction: a rabbit model.
Topics: Animals; Cartilage; Disease Models, Animal; Feasibility Studies; Gastroesophageal Reflux; Hydrochlor | 2001 |
Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat.
Topics: Animals; beta-Endorphin; Brain; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; | 2001 |
Nitric oxide inhalation increases alveolar gas exchange by decreasing deadspace volume.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Carbon Dioxide; Cross-Over Studies; Disea | 2001 |
Laryngospasm and diaphragmatic arrest in immature dogs after laryngeal acid exposure: a possible model for sudden infant death syndrome.
Topics: Animals; Animals, Newborn; Apnea; Diaphragm; Disease Models, Animal; Dogs; Electromyography; Humans; | 2001 |
Effects of diacerein on indomethacin-induced gastric ulceration.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Dinoprostone; D | 2001 |
The role of substance P release in the lung with esophageal acid.
Topics: Animals; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Esophagus; Extravasat | 2001 |
Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Endothelium; Hemodynamics; Hydrochloric Acid; P | 2002 |
Serum SP-D is a marker of lung injury in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Disea | 2002 |
Gastroprotective activity of the diterpene solidagenone and its derivatives on experimentally induced gastric lesions in mice.
Topics: Animals; Anti-Ulcer Agents; Biotransformation; Disease Models, Animal; Diterpenes; Ethanol; Furans; | 2002 |
Failure of cholestyramine to prevent bile salt injury to mouse gastric mucosa.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestyramine Resin; Disease Models, Animal; | 1975 |
Ventilation and blood-gas studies during experimentally produced Mendelson's syndrome in the dog.
Topics: Acidosis, Respiratory; Anesthesia, General; Animals; Carbon Dioxide; Disease Models, Animal; Dogs; F | 1975 |
Immediate histopathology of hydrochloric acid aspiration.
Topics: Animals; Disease Models, Animal; Dogs; Hemorrhage; Hydrochloric Acid; Lung Diseases; Male; Microcirc | 1979 |
[Animal model of acute respiratory insufficiency by HCl aspiration in Lewe mini-pigs].
Topics: Acute Disease; Animals; Blood Gas Analysis; Disease Models, Animal; Hydrochloric Acid; Lung Complian | 1979 |
Distention ulcer as a model for testing of drugs for ulcerogenic side effects.
Topics: Animals; Aspirin; Disease Models, Animal; Hydrochloric Acid; Indomethacin; Male; Rats; Stomach; Stom | 1978 |
The primary antibacterial defense mechanism of the bladder.
Topics: Animals; Antibiosis; Bacterial Infections; Disease Models, Animal; Escherichia coli; Female; Humans; | 1975 |
Haemodynamic effects of selective positive end-expiratory pressure after unilateral pulmonary hydrochloric acid-aspiration in dogs.
Topics: Animals; Cardiac Output; Disease Models, Animal; Dogs; Evaluation Studies as Topic; Functional Resid | 1992 |
Continuous versus intermittent acid exposure in production of esophagitis in feline model.
Topics: Analysis of Variance; Animals; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Esoph | 1992 |
A reliable method for the production of antral gastric ulcer by a combination of 2-deoxy-D-glucose, aspirin and ammonia in rats.
Topics: Administration, Oral; Ammonia; Animals; Aspirin; Deoxyglucose; Disease Models, Animal; Drug Interact | 1991 |
[Effect of superimposed high frequency oscillation on pulmonary edema induced by intrapulmonary injection of hydrochloric acid in dogs].
Topics: Animals; Disease Models, Animal; Dogs; High-Frequency Ventilation; Hydrochloric Acid; Pulmonary Edem | 1991 |
The histologic development of acid-induced esophagitis in the cat.
Topics: Animals; Cats; Disease Models, Animal; Esophagitis, Peptic; Hydrochloric Acid; Hyperplasia; Infusion | 1990 |
Chemotactic factor generation and cell accumulation in acute lung injury induced by endotracheal acid instillation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemotactic Factors; Complement C5; Complement C5 | 1989 |
Effect of cytoprotective and antiulcer drugs on the healing process of subacute gastric ulcer in rat (a new model).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Disease Models, Animal; Ethylma | 1989 |
The free radical mechanisms in beta-carotene induced gastric cytoprotection in HCl model.
Topics: Animals; beta Carotene; Carotenoids; Catalase; Disease Models, Animal; Female; Free Radicals; Gastri | 1989 |
Conjugated diene production after airway acid aspiration.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Female; Free Radicals; Hydrochloric Aci | 1989 |
Hemodynamic effects of nifedipine in a canine model of acid aspiration.
Topics: Animals; Disease Models, Animal; Dogs; Hemodynamics; Hydrochloric Acid; Nifedipine; Pneumonia, Aspir | 1988 |
Sites of leakage in three models of acute lung injury.
Topics: Animals; Arteries; Arterioles; Blood Pressure; Capillary Permeability; Disease Models, Animal; Embol | 1988 |
Endogenous opioids do not mediate HCl-induced myocardial dysfunction.
Topics: Acidosis; Animals; Animals, Newborn; Asphyxia Neonatorum; Bradycardia; Cardiac Output, Low; Disease | 1988 |
Acid ingestion in an experimental model.
Topics: Acids; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Caustics; Child, Preschool; Disease | 1985 |
Intrajejunal administration of an elemental diet at neutral pH avoids pancreatic stimulation. Studies in dog and man.
Topics: Acetates; Amino Acids; Animals; Disease Models, Animal; Duodenum; Female; Glucose; Humans; Hydrochlo | 1973 |
[Fluoresceinangiography in experimental quinine poisoning (author's transl)].
Topics: Action Potentials; Acute Disease; Animals; Disease Models, Animal; Electroretinography; Fluorescein | 1974 |
[Experimental peptic ulcer in rats].
Topics: Animals; Disease Models, Animal; Female; Gastric Mucosa; Hydrochloric Acid; Male; Methods; Peptic Ul | 1972 |
Steroid treatment for acid-aspiration pneumonitis.
Topics: Animals; Blood; Body Weight; Carbon Dioxide; Dexamethasone; Disease Models, Animal; Hydrochloric Aci | 1974 |
The role of vagotomy in preventing bile salt-induced stress ulcers during hemorrhagic shock.
Topics: Animals; Bile Acids and Salts; Disease Models, Animal; Dogs; Gastric Mucosa; Hydrochloric Acid; Hydr | 1972 |
Acute response to acid-base stress in the dog.
Topics: Acidosis; Alkalosis; Ammonium Chloride; Animals; Bicarbonates; Blood; Carbon Dioxide; Computers; Dis | 1972 |
Experimental gastroduodenal ulcer.
Topics: Animals; Disease Models, Animal; Dogs; Duodenum; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; M | 1971 |
The acute effect of acid aspiration on lung mechanics and gas exchange in the rabbit.
Topics: Acidosis, Respiratory; Animals; Blood Pressure Determination; Carbon Dioxide; Disease Models, Animal | 1971 |
Ultrastructural elements in experimental intimal thickening. I. Electron microscopic study of the development and cellular elements of intimal proliferation.
Topics: Animals; Aorta, Abdominal; Arteries; Arteriosclerosis; Cell Membrane; Disease Models, Animal; Elasti | 1969 |
Ultrastructural elements in experimental intimal thickening. II. Study of the development of elastic elements in intimal proliferation.
Topics: Animals; Aorta, Abdominal; Arteries; Arteriosclerosis; Basement Membrane; Disease Models, Animal; El | 1969 |
[The pathogenesis of acute pancreatitis].
Topics: Acute Disease; Animals; Disease Models, Animal; Hydrochloric Acid; Pancreatitis; Peptide Hydrolases; | 1970 |