Page last updated: 2024-10-17

hydrochloric acid and Aging

hydrochloric acid has been researched along with Aging in 28 studies

Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"HCl induced pulmonary fibrosis with an increased Ashcroft score, which was higher in adults, and a reduction in alveolar Mean Alveolar Linear Intercept (MALI)."5.62Age-Dependent Chronic Lung Injury and Pulmonary Fibrosis following Single Exposure to Hydrochloric Acid. ( Catravas, JD; Colunga Biancatelli, RML; Dimitropoulou, C; Solopov, P, 2021)
"To access the efficacy of cisapride in facilitating acid clearance in patients with symptomatic gastro-oesophageal reflux disease."5.09The role of age and salivation in acid clearance in symptomatic patients with gastro-oesophageal reflux disease. ( Chen, CL; Orr, WC; Sloan, S, 2001)
" One group of neonates at high risk for SIDS includes those who develop apnea secondary to gastroesophageal reflux (GER)."4.78Effects of acid on the larynx of the maturing rabbit and their possible significance to the sudden infant death syndrome. ( Wetmore, RF, 1993)
"HCl induced pulmonary fibrosis with an increased Ashcroft score, which was higher in adults, and a reduction in alveolar Mean Alveolar Linear Intercept (MALI)."1.62Age-Dependent Chronic Lung Injury and Pulmonary Fibrosis following Single Exposure to Hydrochloric Acid. ( Catravas, JD; Colunga Biancatelli, RML; Dimitropoulou, C; Solopov, P, 2021)
"older patients with gastro-oesophageal reflux disease have reduced symptom severity for heartburn despite a tendency towards increased severity of oesophageal mucosal injury and acid exposure."1.31Symptom severity and oesophageal chemosensitivity to acid in older and young patients with gastro-oesophageal reflux. ( Fass, R; Garewal, HS; Johnson, C; Pulliam, G; Sampliner, RE, 2000)
"Patients with Barrett's esophagus have demonstrated reduced chemo- and mechanoreceptor sensitivity to acid infusion and balloon distension, respectively."1.30Reduced chemoreceptor sensitivity in patients with Barrett's esophagus may be related to age and not to the presence of Barrett's epithelium. ( Fass, R; Garewal, H; Grade, A; Johnson, C; Pulliam, G; Sampliner, RE, 1997)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199013 (46.43)18.7374
1990's7 (25.00)18.2507
2000's5 (17.86)29.6817
2010's2 (7.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Colunga Biancatelli, RML1
Solopov, P1
Dimitropoulou, C1
Catravas, JD1
Chen, CL2
Yi, CH1
Liu, TT1
Orr, WC2
Yamasaki, T1
Oshima, T1
Tomita, T1
Kondo, T1
Toyoshima, F1
Sakurai, J1
Fukui, H1
Matsumoto, T1
Watari, J1
Miwa, H1
MEYER, E1
GLANVILLE, EV1
KAPLAN, AR1
FISCHER, R1
St-Hilaire, M1
Samson, N1
Duvareille, C1
Praud, JP1
Apostolopoulos, KN1
Deligianni, DD1
Malcolm, R1
O'Neil, PM1
Hirsch, AA1
Currey, HS1
Moskowitz, G1
Wetmore, RF1
Dimarogonas, AD1
Abbasi-Jahromi, SH1
Avioli, LV1
Coffey, RD1
Cromwell, GL1
Seno, K1
Lam, K1
Leung, JW1
Leung, FW1
Grade, A1
Pulliam, G2
Johnson, C2
Garewal, H1
Sampliner, RE2
Fass, R2
Kaneko, H1
Tabata, M1
Tomomasa, T1
Morikawa, A1
Garewal, HS1
Morishima-Kawashima, M1
Oshima, N1
Ogata, H1
Yamaguchi, H1
Yoshimura, M1
Sugihara, S1
Ihara, Y1
Sloan, S1
Upton, PK1
L'Estrange, JL1
Krug, H1
Martin, R1
Martin, H1
Korkuschko, OW1
Tereschtschenko, WP1
Miller, TA1
Tepperman, BL1
Soper, BD1
Zunnunova, SE1
Stevens, WS1
Rodgers, BM1
Denkhaus, W1
Kiefer, G1
Meuter, P1
Köteles, GJ1
Antoni, F1
Solymossy, M1
Feraudi, M1
Conger, AD1
Wells, MA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265]Phase 418 participants (Actual)Interventional2006-08-31Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.)
Study of a Dietary Supplement for Reflux During Sleep[NCT02274636]50 participants (Anticipated)Interventional2014-10-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrochloric acid and Aging

ArticleYear
Effects of acid on the larynx of the maturing rabbit and their possible significance to the sudden infant death syndrome.
    The Laryngoscope, 1993, Volume: 103, Issue:11 Pt 1

    Topics: Aging; Airway Obstruction; Animals; Apnea; Female; Gastroesophageal Reflux; Humans; Hydrochloric Aci

1993

Trials

1 trial available for hydrochloric acid and Aging

ArticleYear
The role of age and salivation in acid clearance in symptomatic patients with gastro-oesophageal reflux disease.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:9

    Topics: Aged; Aging; Anti-Ulcer Agents; Cisapride; Deglutition; Gastroesophageal Reflux; Humans; Hydrochlori

2001

Other Studies

26 other studies available for hydrochloric acid and Aging

ArticleYear
Age-Dependent Chronic Lung Injury and Pulmonary Fibrosis following Single Exposure to Hydrochloric Acid.
    International journal of molecular sciences, 2021, Aug-17, Volume: 22, Issue:16

    Topics: Acute Lung Injury; Aging; Animals; Bronchoalveolar Lavage Fluid; Hydrochloric Acid; Inflammation; Ma

2021
Altered sensorimotor responses to esophageal acidification in older adults with GERD.
    Scandinavian journal of gastroenterology, 2010, Volume: 45, Issue:10

    Topics: Adult; Age Factors; Aged; Aging; Esophageal pH Monitoring; Esophagoscopy; Esophagus; Female; Gastroe

2010
Effect of age and correlation between esophageal visceral chemosensitivity and mechanosensitivity in healthy Japanese subjects.
    Journal of gastroenterology, 2013, Volume: 48, Issue:3

    Topics: Adult; Aged; Aging; Dilatation; Esophagus; Female; Humans; Hydrochloric Acid; Male; Manometry; Mecha

2013
[On the incidence of hydrochloric acid deficiency in advanced age (with a statement on the usefulness of the desmoid test)].
    Munchener medizinische Wochenschrift (1950), 1963, Jan-25, Volume: 105

    Topics: Achlorhydria; Aging; Anemia; Fibromatosis, Aggressive; Gastric Acidity Determination; Humans; Hydroc

1963
AGE, SEX, AND TASTE SENSITIVITY.
    Journal of gerontology, 1964, Volume: 19

    Topics: Aging; Genetics, Medical; Humans; Hydrochloric Acid; Quinine; Sex; Sulfates; Taste; Thiouracil

1964
Laryngeal stimulation by an acid solution in the pre-term lamb.
    Advances in experimental medicine and biology, 2008, Volume: 605

    Topics: Aging; Animals; Animals, Newborn; Citric Acid; Disease Models, Animal; Gastroesophageal Reflux; Hydr

2008
Influence of microarchitecture alterations on ultrasonic backscattering in an experimental simulation of bovine cancellous bone aging.
    The Journal of the Acoustical Society of America, 2008, Volume: 123, Issue:2

    Topics: Aging; Algorithms; Animals; Bone Demineralization Technique; Calcium; Cattle; Femur; Hydrochloric Ac

2008
Taste hedonics and thresholds in obesity.
    International journal of obesity, 1980, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aging; Female; Humans; Hydrochloric Acid; Obesity; Osmolar Concentration; Sodium

1980
Material damping for monitoring of density and strength of bones.
    Calcified tissue international, 1993, Volume: 52, Issue:3

    Topics: Aging; Animals; Bone and Bones; Bone Density; Chickens; Femur; Hydrochloric Acid; In Vitro Technique

1993
The impact of environment and antimicrobial agents on the growth response of early-weaned pigs to spray-dried porcine plasma.
    Journal of animal science, 1995, Volume: 73, Issue:9

    Topics: Aging; Animals; Anti-Bacterial Agents; Blood Proteins; Copper; Eating; Environment; Female; Hydrochl

1995
Aging impairs afferent nerve function in rat intestine. Reduction of mesenteric hyperemia induced by intraduodenal capsaicin and acid.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:2

    Topics: Afferent Pathways; Aging; Animals; Capsaicin; Duodenum; Hydrochloric Acid; Hyperemia; Intestinal Muc

1996
Reduced chemoreceptor sensitivity in patients with Barrett's esophagus may be related to age and not to the presence of Barrett's epithelium.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:11

    Topics: Adult; Aged; Aging; Barrett Esophagus; Chemoreceptor Cells; Epithelium; Esophagus; Follow-Up Studies

1997
Effect of age and weaning on gastric mucosal injury in developing rats.
    Biology of the neonate, 1999, Volume: 75, Issue:2

    Topics: Aging; Animals; Ethanol; Gastric Mucosa; Hydrochloric Acid; Rats; Rats, Wistar; Stomach Diseases; We

1999
Symptom severity and oesophageal chemosensitivity to acid in older and young patients with gastro-oesophageal reflux.
    Age and ageing, 2000, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochlo

2000
Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain.
    The American journal of pathology, 2000, Volume: 157, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipopro

2000
Effects of chronic hydrochloric and lactic acid administrations on food intake, blood acid-base balance and bone composition of the rat.
    Quarterly journal of experimental physiology and cognate medical sciences, 1977, Volume: 62, Issue:3

    Topics: Acid-Base Equilibrium; Aging; Animals; Body Weight; Bone and Bones; Calcium; Diet; Eating; Hydrochlo

1977
[Pulse cytophotometrical investigations about the resistance of DNA against acid hydrolysis influenced by ageing and cortisol (author's transl)].
    Acta histochemica, 1978, Volume: 63, Issue:1

    Topics: Aging; Animals; Chromatin; Cytological Techniques; DNA; Drug Resistance; Hydrochloric Acid; Hydrocor

1978
[The secretory function of the pancreas and the ageing progress (author's transl)].
    Zeitschrift fur Alternsforschung, 1976, Volume: 31, Issue:2

    Topics: Adult; Aged; Aging; Amylases; Bicarbonates; Blood Glucose; Cholecystokinin; Female; Humans; Hydrochl

1976
Bicarbonate secretory breakdown: explanation for increased incidence of duodenal ulcer with age?
    Gastroenterology, 1991, Volume: 100, Issue:5 Pt 1

    Topics: Adult; Aged; Aging; Animals; Bicarbonates; Dinoprostone; Duodenal Ulcer; Duodenum; Female; Humans; H

1991
Effect of epidermal growth factor on the ontogenic response of rat gastric mucosa to H+.
    The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 1

    Topics: Aging; Animals; Duodenum; Epidermal Growth Factor; Female; Gastric Acid; Gastric Mucosa; Hydrochlori

1989
[Comparative characteristics of the pancreatic exocrine activity in rats of various ages].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1987, Volume: 73, Issue:12

    Topics: Aging; alpha-Amylases; Animals; Hydrochloric Acid; Lipase; Male; Pancreas; Pancreatic Juice; Peptide

1987
The effect of antral acidification on serum gastrin levels in neonatal pigs.
    The Journal of surgical research, 1988, Volume: 45, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Female; Gastric Acid; Gastrins; Hydrochloric Acid; Hydrogen-Ion Co

1988
[Studies on the acid lability of nucleoproteids occurring with age].
    Virchows Archiv. B, Cell pathology, 1969, Volume: 3, Issue:2

    Topics: Accidents; Adolescent; Adult; Age Factors; Aged; Aging; Brain Injuries; Cell Nucleus; Female; Histoc

1969
On the existence of a strongly acid-soluble protein fraction in the eye lens.
    Acta biochimica et biophysica; Academiae Scientiarum Hungaricae, 1971, Volume: 6, Issue:4

    Topics: Aging; Amino Acids; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Crystallins; Eye Protei

1971
[Measurement of ATP: D-glyceraldehyde-3-phosphotransferase activity. EC 2.7.1.28 (Triokinase)].
    Enzymologia biologica et clinica, 1970, Volume: 11, Issue:5

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Aging; Amino Alcohols; Animals; Esters; Female; Fetus;

1970
Radiation and aging effect on taste structure and function.
    Radiation research, 1969, Volume: 37, Issue:1

    Topics: Aging; Animals; Head and Neck Neoplasms; Humans; Hydrochloric Acid; Mice; Quinine; Radiation Effects

1969