hydrochloric acid has been researched along with Ache in 49 studies
Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effects of pregabalin on development of secondary oesophageal hypersensitivity in healthy humans." | 9.16 | Randomised clinical trial: pregabalin attenuates the development of acid-induced oesophageal hypersensitivity in healthy volunteers - a placebo-controlled study. ( Aziz, Q; Chua, YC; Jafari, J; Knowles, CH; Ng, KS; Sharma, A; Surguy, S; Yazaki, E, 2012) |
| "We hypothesized that chemically-induced hyperalgesia in the oesophagus could provoke widespread visceral hypersensitivity and also influence descending modulatory pain pathways." | 5.36 | Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus. ( Andresen, T; Arendt-Nielsen, L; Brock, C; Drewes, AM; Frøkjaer, JB; Gale, J; Olesen, AE, 2010) |
| "To study the effects of pregabalin on development of secondary oesophageal hypersensitivity in healthy humans." | 5.16 | Randomised clinical trial: pregabalin attenuates the development of acid-induced oesophageal hypersensitivity in healthy volunteers - a placebo-controlled study. ( Aziz, Q; Chua, YC; Jafari, J; Knowles, CH; Ng, KS; Sharma, A; Surguy, S; Yazaki, E, 2012) |
| "Twelve healthy controls and 39 patients with reflux disease [14 erosive reflux disease, 11 non-erosive reflux disease with normal (functional heartburn) and 14 non-erosive reflux disease with excess acid exposure] had hydrochloric acid and saline infused into distal and then proximal oesophagus." | 3.74 | Acid-related oesophageal sensitivity, not dysmotility, differentiates subgroups of patients with non-erosive reflux disease. ( Emmanuel, AV; Kalantzis, C; Khoo, D; Thoua, NM, 2008) |
| "Pain is commonly the initial symptom in peptic ulcer, but the mechanism is controversial." | 2.37 | Ulcer pain mechanisms. The clinical features of active peptic ulcer disease and implications for therapy. ( Texter, EC, 1987) |
| "We hypothesized that chemically-induced hyperalgesia in the oesophagus could provoke widespread visceral hypersensitivity and also influence descending modulatory pain pathways." | 1.36 | Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus. ( Andresen, T; Arendt-Nielsen, L; Brock, C; Drewes, AM; Frøkjaer, JB; Gale, J; Olesen, AE, 2010) |
| "Distal esophageal acidification induces hyperalgesia in the non-acid exposed proximal esophagus, due to the sensitization of spinal dorsal horn neurones." | 1.36 | Anxiety increases acid-induced esophageal hyperalgesia. ( Aziz, Q; Gregory, L; Paine, P; Sharma, A; Van Oudenhove, L, 2010) |
| "Although coronary artery disease and gastroesophageal reflux disease are common conditions which, therefore, may coexist, it is unknown whether or not the presence of one affects the other." | 1.27 | Esophageal acid perfusion in coronary artery disease. Induction of myocardial ischemia. ( Haye, OL; Mellow, MH; Schoolmeester, L; Simpson, AG; Watt, L, 1983) |
| "Primary symptoms include dysphagia, odynophagia, heartburn and central chest pain." | 1.27 | Evaluation of esophageal diseases. ( Dabaghi, RE; Scott, LD, 1986) |
| "the pain has been analyzed to determine its characteristic and its atypical features." | 1.26 | Characteristics of esophageal pain. ( Henderson, RD; Marryatt, G, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (61.22) | 18.7374 |
| 1990's | 6 (12.24) | 18.2507 |
| 2000's | 6 (12.24) | 29.6817 |
| 2010's | 6 (12.24) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, JH | 1 |
| Ryu, CM | 1 |
| Yu, HY | 1 |
| Park, YS | 1 |
| Shin, DM | 1 |
| Choo, MS | 1 |
| Hamdi, A | 1 |
| Majouli, K | 1 |
| Abdelhamid, A | 1 |
| Marzouk, B | 1 |
| Belghith, H | 1 |
| Chraief, I | 1 |
| Bouraoui, A | 1 |
| Marzouk, Z | 1 |
| Heyden, YV | 1 |
| Brock, C | 1 |
| Andresen, T | 1 |
| Frøkjaer, JB | 1 |
| Gale, J | 1 |
| Olesen, AE | 1 |
| Arendt-Nielsen, L | 2 |
| Drewes, AM | 4 |
| Krarup, AL | 2 |
| Villadsen, GE | 1 |
| Mejlgaard, E | 1 |
| Olesen, SS | 1 |
| Funch-Jensen, P | 3 |
| Sharma, A | 2 |
| Van Oudenhove, L | 1 |
| Paine, P | 1 |
| Gregory, L | 1 |
| Aziz, Q | 2 |
| Simrén, M | 1 |
| Hansen, MB | 1 |
| Hvid-Jensen, F | 1 |
| Brun, J | 1 |
| Chua, YC | 1 |
| Ng, KS | 1 |
| Jafari, J | 1 |
| Surguy, S | 1 |
| Yazaki, E | 1 |
| Knowles, CH | 1 |
| DEKKERS, HJ | 1 |
| TEODORESCU, P | 1 |
| SAVULESCU, V | 1 |
| ANDRONACHE, I | 1 |
| Dong, JC | 1 |
| Wang, X | 1 |
| Li, RT | 1 |
| Zhang, HM | 1 |
| Cheng, TM | 1 |
| Li, CL | 1 |
| Jones, NG | 1 |
| Slater, R | 1 |
| Cadiou, H | 1 |
| McNaughton, P | 1 |
| McMahon, SB | 1 |
| Reddy, H | 1 |
| Staahl, C | 1 |
| Gregersen, H | 1 |
| Lundbye-Christensen, S | 1 |
| Thoua, NM | 1 |
| Khoo, D | 1 |
| Kalantzis, C | 1 |
| Emmanuel, AV | 1 |
| Lawal, A | 1 |
| Kern, M | 1 |
| Sanjeevi, A | 1 |
| Antonik, S | 1 |
| Mepani, R | 1 |
| Rittmann, T | 1 |
| Hussaini, S | 1 |
| Hofmann, C | 1 |
| Tatro, L | 1 |
| Jesmanowicz, A | 1 |
| Verber, M | 1 |
| Shaker, R | 1 |
| Joffe, SN | 1 |
| Primrose, JN | 1 |
| Shamsi, Z | 1 |
| Anwar, A | 1 |
| Mellow, MH | 1 |
| Simpson, AG | 1 |
| Watt, L | 1 |
| Schoolmeester, L | 1 |
| Haye, OL | 1 |
| Henderson, RD | 1 |
| Marryatt, G | 1 |
| Bright-Asare, P | 1 |
| El-Bassoussi, M | 1 |
| Wranne, B | 2 |
| Areskog, M | 2 |
| Tibbling, L | 3 |
| Harrison, A | 1 |
| Isenberg, JI | 1 |
| Schapira, M | 1 |
| Hagie, L | 1 |
| Holzer-Petsche, U | 1 |
| Rordorf-Nikolić, T | 1 |
| Son, HJ | 1 |
| Rhee, PL | 1 |
| Kim, JJ | 1 |
| Koh, KC | 1 |
| Paik, SW | 1 |
| Rhee, JC | 1 |
| Hanamori, T | 1 |
| Kunitake, T | 1 |
| Kato, K | 1 |
| Kannan, H | 1 |
| Kawasaki, M | 1 |
| Kimura, I | 1 |
| Matsuda, A | 1 |
| Kataoka, M | 1 |
| Kokuba, Y | 1 |
| Schuligoi, R | 1 |
| Jocic, M | 1 |
| Heinemann, A | 1 |
| Schöninkle, E | 1 |
| Pabst, MA | 1 |
| Holzer, P | 1 |
| Hamamoto, DT | 1 |
| Forkey, MW | 1 |
| Davis, WL | 1 |
| Kajander, KC | 1 |
| Simone, DA | 1 |
| Littman, A | 1 |
| Welch, R | 1 |
| Fruin, RC | 1 |
| Aronson, AR | 1 |
| Dilawari, JB | 1 |
| Blendis, LM | 1 |
| Edwards, DA | 1 |
| James, O | 2 |
| Kenefick, JS | 2 |
| Misra, SP | 1 |
| Broor, SL | 1 |
| Kang, JY | 2 |
| Yap, I | 2 |
| Guan, R | 2 |
| Tay, HH | 2 |
| Math, MV | 1 |
| Earlam, R | 2 |
| Cole, MJ | 1 |
| Paterson, WG | 1 |
| Beck, IT | 1 |
| DaCosta, LR | 1 |
| Texter, EC | 1 |
| Dabaghi, RE | 1 |
| Scott, LD | 1 |
| Kjellén, G | 1 |
| Atkinson, M | 1 |
| Bennett, JR | 1 |
| Earlam, RJ | 2 |
| Crozier, RE | 1 |
| Gregg, JA | 1 |
| Garabedian, MM | 1 |
| de Geus, A | 1 |
| Sebus, J | 1 |
| Charbon, GA | 1 |
| de Groot, CJ | 1 |
| Estaba, V | 1 |
| Franklin, M | 1 |
| Floch, MH | 1 |
| Schwarz, V | 1 |
| Sutcliffe, CH | 1 |
| Style, PP | 1 |
2 reviews available for hydrochloric acid and Ache
| Article | Year |
|---|---|
The acid perfusion test as differential diagnostic aid in patients with chest pain.
Topics: Diagnosis, Differential; Esophageal Diseases; Exercise Test; Heart Diseases; Humans; Hydrochloric Ac | 1981 |
Ulcer pain mechanisms. The clinical features of active peptic ulcer disease and implications for therapy.
Topics: Fluoroscopy; Gastric Acidity Determination; Gastrointestinal Motility; Humans; Hydrochloric Acid; Mo | 1987 |
8 trials available for hydrochloric acid and Ache
| Article | Year |
|---|---|
Randomised clinical trial: pregabalin attenuates the development of acid-induced oesophageal hypersensitivity in healthy volunteers - a placebo-controlled study.
Topics: Adult; Analgesics; Cross-Over Studies; Double-Blind Method; Esophageal Diseases; Female; gamma-Amino | 2012 |
Cimetidine, metoclopramide, or placebo in the treatment of symptomatic gastroesophageal reflux.
Topics: Adult; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Gastroesophageal Reflux; G | 1980 |
Most patients with active symptomatic duodenal ulcers fail to develop ulcer-type pain in response to gastroduodenal acidification.
Topics: Adult; Aged; Citrates; Citric Acid; Double-Blind Method; Duodenal Ulcer; Humans; Hydrochloric Acid; | 1982 |
Hypersensitivity to acid in ulcer-like functional dyspepsia.
Topics: Adult; Dyspepsia; Female; Humans; Hydrochloric Acid; Male; Middle Aged; Pain; Peptic Ulcer | 1997 |
Controlled trials of aluminum hydroxide gels for peptic ulcer.
Topics: Aluminum Hydroxide; Analgesia; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer; Humans; Hy | 1977 |
Is gastric acid responsible for the pain in patients with essential dyspepsia?
Topics: Adolescent; Adult; Double-Blind Method; Dyspepsia; Female; Gastric Acid; Humans; Hydrochloric Acid; | 1990 |
Acid induced duodenal ulcer pain: the influence of symptom status and the effect of an antispasmodic.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Duodenal | 1989 |
Acid perfusion of duodenal ulcer craters and ulcer pain: a controlled double blind study.
Topics: Adult; Aged; Double-Blind Method; Duodenal Ulcer; Female; Humans; Hydrochloric Acid; Male; Middle Ag | 1986 |
39 other studies available for hydrochloric acid and Ache
| Article | Year |
|---|---|
Therapeutic effects of axitinib, an anti-angiogenic tyrosine kinase inhibitor, on interstitial cystitis.
Topics: Animals; Axitinib; Cystitis, Interstitial; Female; Hydrochloric Acid; Pain; Protein Kinase Inhibitor | 2023 |
Pharmacological activities of the organic extracts and fatty acid composition of the petroleum ether extract from Haplophyllum tuberculatum leaves.
Topics: Acetic Acid; Alkanes; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; | 2018 |
Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus.
Topics: Adult; Analysis of Variance; Body Temperature; Capsaicin; Cerebral Cortex; Electric Stimulation; Ele | 2010 |
Acid hypersensitivity in patients with eosinophilic oesophagitis.
Topics: Adult; Aged; Case-Control Studies; Esophagitis; Female; Humans; Hydrochloric Acid; Hyperalgesia; Mal | 2010 |
Anxiety increases acid-induced esophageal hyperalgesia.
Topics: Adult; Affect; Anxiety; Autonomic Nervous System; Baroreflex; Cross-Over Studies; Esophageal Disease | 2010 |
The esophageal multimodal pain model: normal values and degree of sensitization in healthy young male volunteers.
Topics: Adult; Electricity; Esophagus; Gastroesophageal Reflux; Hot Temperature; Humans; Hydrochloric Acid; | 2011 |
[The connection between pain and emptying of the stomach in duodenal ulcer patients, with hydrochloric acid determination during digestion].
Topics: Digestion; Duodenal Ulcer; Gastric Juice; Humans; Hydrochloric Acid; Pain; Peptic Ulcer; Stomach | 1960 |
[PHARMACODYNAMIC TESTS IN THE DIAGNOSIS OF ULCEROUS DISEASE. I. VALUE OF SOME DIAGNOSTIC TESTS TO INDUCE ULCEROUS PAINS BY MOTOR AND SECRETORY FUNCTIONAL OVERLOAD].
Topics: Biological Transport; Diagnosis; Diagnostic Tests, Routine; Histamine; Hydrochloric Acid; Insulin; P | 1963 |
Synthesis and analgesic activity of hydrochlorides and quaternary ammoniums of epibatidine incorporated with amino acid ester.
Topics: Amino Acids; Analgesics, Non-Narcotic; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dose-Respon | 2003 |
Acid-induced pain and its modulation in humans.
Topics: Acid Sensing Ion Channels; Administration, Cutaneous; Adult; Amiloride; Analgesics; Anti-Inflammator | 2004 |
Statistical modeling of the response characteristics of mechanosensitive stimuli in the human esophagus.
Topics: Action Potentials; Adult; Afferent Pathways; Butylscopolammonium Bromide; Esophagus; Female; Humans; | 2005 |
Acid-related oesophageal sensitivity, not dysmotility, differentiates subgroups of patients with non-erosive reflux disease.
Topics: Adult; Case-Control Studies; Esophageal Motility Disorders; Esophagoscopy; Female; Gastroesophageal | 2008 |
Neurocognitive processing of esophageal central sensitization in the insula and cingulate gyrus.
Topics: Adolescent; Adult; Catheterization; Cerebral Cortex; Cognition; Dilatation; Esophagus; Female; Gastr | 2008 |
Pain provocation test in peptic duodenitis.
Topics: Bicarbonates; Duodenitis; Endoscopy; Humans; Hydrochloric Acid; Methods; Pain; Sodium Bicarbonate; S | 1983 |
Intraesophageal acid perfusion test (Bernstein test).
Topics: Esophagitis, Peptic; Esophagus; Humans; Hydrochloric Acid; Intubation; Pain | 1984 |
Esophageal acid perfusion in coronary artery disease. Induction of myocardial ischemia.
Topics: Angina Pectoris; Angiography; Blood Pressure; Cardiomyopathies; Coronary Disease; Diagnosis, Differe | 1983 |
Characteristics of esophageal pain.
Topics: Diagnosis, Differential; Food; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Pain; | 1981 |
Central versus peripheral site of action of the tachykinin NK1-antagonist RP 67580 in inhibiting chemonociception.
Topics: Analgesics; Animals; Blood Pressure; Blood-Brain Barrier; Capsaicin; Female; Hydrochloric Acid; Indo | 1995 |
Neurons in the posterior insular cortex are responsive to gustatory stimulation of the pharyngolarynx, baroreceptor and chemoreceptor stimulation, and tail pinch in rats.
Topics: Animals; Brain Mapping; Cerebral Cortex; Chemoreceptor Cells; Hydrochloric Acid; Laryngeal Nerves; L | 1998 |
[Influence of infusion solution on the vascular permeability in rat skin].
Topics: Acetic Acid; Animals; Capillary Permeability; Coloring Agents; Hydrochloric Acid; Hydrogen-Ion Conce | 1998 |
Gastric acid-evoked c-fos messenger RNA expression in rat brainstem is signaled by capsaicin-resistant vagal afferents.
Topics: Afferent Pathways; Animals; Brain Stem; Capsaicin; Female; Gastric Acid; Gastric Mucosa; Genes, fos; | 1998 |
The role of pH and osmolarity in evoking the acetic acid-induced wiping response in a model of nociception in frogs.
Topics: Acetic Acid; Animals; Behavior, Animal; Buffers; Disease Models, Animal; Epidermis; Formates; Hydroc | 2000 |
Oesophageal acid perfusion test as a complement to work test in patients with chest pain.
Topics: Adult; Aged; Angina Pectoris; Diagnosis, Differential; Electrocardiography; Esophageal Diseases; Exe | 1977 |
Epigastric pain in duodenal ulcer.
Topics: Bicarbonates; Duodenal Ulcer; Esophagogastric Junction; Gastroesophageal Reflux; Humans; Hydrochlori | 1975 |
Pain in peptic ulcer.
Topics: Endoscopy; Female; Humans; Hydrochloric Acid; Male; Pain; Peptic Ulcer | 1975 |
On the origin of duodenal-ulcer pain.
Topics: Duodenal Ulcer; Esophagus; Humans; Hydrochloric Acid; Pain | 1985 |
The effect of acid and bethanechol stimulation in patients with symptomatic hypertensive peristaltic (nutcracker) esophagus. Evidence that this disorder may be a precursor of diffuse esophageal spasm.
Topics: Adult; Aged; Bethanechol; Bethanechol Compounds; Esophageal Diseases; Humans; Hydrochloric Acid; Man | 1986 |
Evaluation of esophageal diseases.
Topics: Barium Sulfate; Deglutition Disorders; Endoscopy; Esophageal Diseases; Esophagus; Fiber Optic Techno | 1986 |
Oesophageal motility during acid-provoked heartburn and chest pain.
Topics: Adult; Aged; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Reflux; Gastrointestinal | 1985 |
Letter: Pain in gastric ulcer.
Topics: Hydrochloric Acid; Pain; Stomach; Stomach Ulcer | 1974 |
Letter: Pain in gastric ulcer.
Topics: Esophagus; Humans; Hydrochloric Acid; Neurons; Pain; Reflex; Stomach Ulcer | 1974 |
Relationship between motor changes and pain during esophageal acid perfusion.
Topics: Bicarbonates; Esophagoscopy; Esophagus; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Hydr | 1968 |
Further experience with epigastric pain reproduction test in duodenal ulceration.
Topics: Bicarbonates; Duodenal Ulcer; Esophagogastric Junction; Esophagus; Humans; Hydrochloric Acid; Pain; | 1972 |
Obscure chest pain as a symptom of reflux esophagitis.
Topics: Adult; Aged; Deglutition Disorders; Endoscopy; Esophagitis; Female; Gastroesophageal Reflux; Gastroi | 1972 |
Chest pain of unknown origin in Kenya Africans.
Topics: Adolescent; Adult; Aged; Black or African American; Black People; Bronchitis; Bronchopneumonia; Card | 1969 |
[Esophageal motility in patients with chest pain].
Topics: Esophageal Diseases; Gastrointestinal Motility; Humans; Hydrochloric Acid; Pain; Radiography | 1970 |
Production of epigastric pain in duodenal ulcer by lower oesophageal acid perfusion.
Topics: Abdomen; Duodenal Ulcer; Esophagus; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Pain; Per | 1970 |
The clinical value of the esophageal acid perfusion test in patients with chest pain.
Topics: Adult; Aged; Coronary Disease; Diagnosis, Differential; Esophagitis; Esophagus; Female; Hernia, Diap | 1968 |
Some hazards of the sweat test.
Topics: Blister; Burns, Chemical; Burns, Electric; Child; Cystic Fibrosis; Electrodiagnosis; Humans; Hydroch | 1968 |