Page last updated: 2024-08-21

hydrazine and Leukemia

hydrazine has been researched along with Leukemia in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199024 (66.67)18.7374
1990's0 (0.00)18.2507
2000's6 (16.67)29.6817
2010's5 (13.89)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Duan, Y; Li, Z; Liu, Z; Song, C; Sun, M; Wang, M; Wang, X; Yao, Y; Zhao, Y1
Baumann, RP; Finch, RA; Penketh, PG; Ratner, ES; Sauro, R; Shyam, K1
Allan, DS; Bredeson, C; Dyba, J; Matthews, J; Tinmouth, A1
Birgens, H; Brown, Pde N; Dalseg, AM; Dufva, IH; Hasselbalch, HC; Jensen, MK; Vangsted, A1
Aivado, M; Chadderton, A; Erickson-Miller, CL; Kirchner, J; May, R; Payne, P1
Advani, A; Cahill, A; Gerson, SL; Karsten, V; Khan, K; LoRusso, S; Moore, J; Rizzieri, D; Tse, W1
Barreyro, L; Bartholdy, B; Mitsiades, CS; Narayanagari, S; Roth, M; Simkin, G; Steidl, U; Tamari, R; Verma, A; Will, B1
Akbar Ali, M; Ali, AM; Butcher, RJ; Keat, TB; Mirza, AH; Tarafder, MT1
Dagarag, MD; Effros, RB; Hausner, MA; Jamieson, BD; Just, T; Matud, JL; Schmid, I1
FREEDLANDER, BL; FURST, A1
FREI, E; FREIREICH, EJ; KARON, M1
HOLLAND, JR; REGELSON, W1
AMIEL, JL; BERUMEN, L; BRULE, G; CATTAN, A; MATHE, G; SCHNEIDER, M; SCHWARZENBERG, L; SCHWEISGUTH, O1
BOLLAG, W; D ALESSANDRI, A; KEEL, HJ; MARTZ, G1
FUJIKAWA, K; INAI, S; MASAOKA, T; NAGAKI, K; TAKAHASHI, H1
ADAMSON, RH; DAVIDSON, JD; DION, RL; LOO, TL1
AMIEL, JL; CATTAN, A; MATHE, G; SCHLUMBERGER, JR; SCHNEIDER, M; SCHWARZENBERG, L2
BEGEMANN, H; BLUM, KU; DREWS, J; FELLMER, KE; FOELSCH, E; GERHARTZ, H; GRUNZE, H; HAUSMANN, K; HENNES, R; JUENGLING, W; KLEIBEL, F; KOERTGE, P; MARING, H; MARTIN, H; OBRECHT, P; OSTEN, W; PABST, HW; POLIWODA, H; SCHUBERT, JC; SEIDL, S; SPECHTER, HJ; STRICKSTROCK, KH; WITTE, S1
BURCHENAL, JH; OETTGEN, HF1
Albitar, M; Cahill, A; Cortes, J; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Gerson, S; Giles, F; Jabbour, E; Kantarjian, H; Karsten, V; Kornblau, S; O'Brien, S; Ravandi, F; Sznol, M; Thomas, D; Verstovsek, S; Yee, K1
Adams, DJ; Giles, F; Jacobsen, TF; Myhren, F; Rizzieri, DA; Sandvold, ML1
Baumann, RP; Ishiguro, K; Penketh, PG; Sartorelli, AC; Seow, HA; Shyam, K1
Rastetter, J; Stockhusen, G; Theml, H; Trepel, F1
Baló, J; Juhász, J; Szende, B1
Kühböck, J; Mannheimer, E; Pietschmann, H1
Armstrong, JG1
Braun, H1
Berceanu, S; Dăncescu, I; Geib, R; Gociu, M; Segal, E; Sighetea, E; Tănăsescu, C1
Clément, F1
Amiel, JL; Bérardet, M1
Billmeier, GJ; Holton, CP1
Deliwala, CV; Dhapalupur, MG; Sabnis, SS1
Botkin, C; Gadekar, K; Kelly, MG; O'Gara, RW; Oliverio, VT; Yancey, ST1
Hildebrand, J; Kenis, Y; Tagnon, HJ; Werli, J1
Berumen, L; Mathé, G; Schneider, M; Schwarzenberg, L1

Reviews

2 review(s) available for hydrazine and Leukemia

ArticleYear
Eltrombopag after allogeneic haematopoietic cell transplantation in a case of poor graft function and systematic review of the literature.
    Transfusion medicine (Oxford, England), 2016, Volume: 26, Issue:3

    Topics: Acute Disease; Allografts; Benzoates; Delayed Graft Function; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Hydrazines; Leukemia; Middle Aged; Pyrazoles

2016
[Novel medical treatment modalities in hematology].
    Ugeskrift for laeger, 2008, Jun-09, Volume: 170, Issue:24

    Topics: Aminoglycosides; Anemia, Hemolytic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Benzamides; Benzoates; Boronic Acids; Bortezomib; Carbazoles; Carrier Proteins; Cyclophosphamide; Dasatinib; Furans; Gemtuzumab; Hematologic Diseases; Humans; Hydrazines; Imatinib Mesylate; Immunologic Factors; Indoles; Lenalidomide; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Piperazines; Purpura, Thrombocytopenic; Pyrazines; Pyrazoles; Pyrimidines; Receptors, Fc; Recombinant Fusion Proteins; Rituximab; Thalidomide; Thiazoles; Thrombopoietin; Vidarabine

2008

Trials

2 trial(s) available for hydrazine and Leukemia

ArticleYear
Phase I study of temozolomide and laromustine (VNP40101M) in patients with relapsed or refractory leukemia.
    Clinical lymphoma, myeloma & leukemia, 2010, Volume: 10, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; History, 16th Century; Humans; Hydrazines; Leukemia; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; O(6)-Methylguanine-DNA Methyltransferase; Sulfonamides; Temozolomide; Young Adult

2010
Phase I study of cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, combined with cytarabine in patients with refractory leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Nov-01, Volume: 11, Issue:21

    Topics: Adult; Aged; Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Base Pair Mismatch; Cohort Studies; Cytarabine; Disease Progression; DNA; DNA Repair; Female; Humans; Hydrazines; Leukemia; Leukocytes, Mononuclear; Male; Middle Aged; Models, Chemical; O(6)-Methylguanine-DNA Methyltransferase; Sulfonamides; Time Factors

2005

Other Studies

32 other study(ies) available for hydrazine and Leukemia

ArticleYear
Discovery of N-(2-oxoethyl) sulfanilamide-derived inhibitors of KAT6A (MOZ) against leukemia by an isostere strategy.
    European journal of medicinal chemistry, 2023, Nov-15, Volume: 260

    Topics: Acetylation; Cell Line; Histone Acetyltransferases; Humans; Hydrazines; Leukemia; Sulfanilamide

2023
pH-dependent general base catalyzed activation rather than isocyanate liberation may explain the superior anticancer efficacy of laromustine compared to related 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine prodrugs.
    Chemical biology & drug design, 2018, Volume: 91, Issue:1

    Topics: Animals; Antineoplastic Agents; Catalysis; Cell Line, Tumor; DNA; Drug Design; Female; Half-Life; Humans; Hydrazines; Hydrogen-Ion Concentration; Isocyanates; Leukemia; Mice; Prodrugs; Protein Carbamylation; Sulfonamides; Transplantation, Homologous

2018
Reduced proliferation of non-megakaryocytic acute myelogenous leukemia and other leukemia and lymphoma cell lines in response to eltrombopag.
    Leukemia research, 2010, Volume: 34, Issue:9

    Topics: Base Sequence; Benzoates; Cell Line, Tumor; Cell Proliferation; DNA Primers; Humans; Hydrazines; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction

2010
Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation.
    Blood, 2012, Jul-12, Volume: 120, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzoates; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; G1 Phase Cell Cycle Checkpoints; HL-60 Cells; Humans; Hydrazines; Iron; Leukemia; Leukemia, Experimental; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Pyrazoles; Receptors, Thrombopoietin; U937 Cells

2012
Biological activity of palladium(II) and platinum(II) complexes of the acetone Schiff bases of S-methyl- and S-benzyldithiocarbazate and the X-ray crystal structure of the [Pd(asme)2] (asme=anionic form of the acetone Schiff base of S-methyldithiocarbazat
    Journal of inorganic biochemistry, 2002, Nov-25, Volume: 92, Issue:3-4

    Topics: Acetone; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Candida; Crystallography, X-Ray; Humans; Hydrazines; Leukemia; Microbial Sensitivity Tests; Molecular Structure; Organometallic Compounds; Palladium; Platinum; Schiff Bases; Tumor Cells, Cultured

2002
Simultaneous flow cytometric analysis of two cell surface markers, telomere length, and DNA content.
    Cytometry, 2002, Nov-01, Volume: 49, Issue:3

    Topics: Antigens, CD; DNA, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hydrazines; In Situ Hybridization, Fluorescence; Leukemia; Leukocytes, Mononuclear; Reproducibility of Results; Staining and Labeling; T-Lymphocyte Subsets; Telomere; Tumor Cells, Cultured

2002
Effect of substituted hydrazines and related compounds on myeloid mouse leukemia C-1498.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 81, Issue:3

    Topics: Hydrazines; Leukemia; Leukemia, Myeloid; Phenylhydrazines

1952
Methylglyoxal bis (guanylhydrazone): a new agent active against acute myelocytic leukemia.
    Cancer chemotherapy reports, 1962, Volume: 16

    Topics: Amidines; Antineoplastic Agents; Humans; Hydrazines; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mitoguazone; Pyruvaldehyde

1962
Clinical experience with methylglyoxal bis (guanylhydrazone) dihydrochloride: a new agent with clinical activity in acute myelocytic leukemia and the lymphomas.
    Cancer chemotherapy reports, 1963, Volume: 27

    Topics: Antineoplastic Agents; Humans; Hydrazines; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Pyruvaldehyde

1963
METHYL-HYDRAZINE IN TREATMENT OF HODGKIN'S DISEASE AND VARIOUS FORMS OF HAEMATOSARCOMA AND LEUKAEMIA.
    Lancet (London, England), 1963, Nov-23, Volume: 2, Issue:7317

    Topics: Antineoplastic Agents; Hodgkin Disease; Hydrazines; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma; Vinblastine

1963
PRELIMINARY CLINICAL RESULTS WITH A NEW ANTITUMOR AGENT RO 4-6467 (NSC-77213).
    Cancer chemotherapy reports, 1963, Volume: 33

    Topics: Antineoplastic Agents; Bone Marrow Diseases; Eosinophilia; Geriatrics; Hemolysis; Hodgkin Disease; Hydrazines; Leukemia; Leukemia, Lymphoid; Lymphocytosis; Lymphoma; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Nausea; Neoplasms; Radiography, Thoracic; Toxicology; Vomiting

1963
DEFICIENCY OF THE HYDRAZINE SENSITIVE COMPONENT OF COMPLEMENT IN A PATIENT WITH CHRONIC MYELOGENOUS LEUKEMIA.
    Biken journal, 1963, Volume: 6

    Topics: Animals; Blood Protein Electrophoresis; Busulfan; Complement System Proteins; Erythrocytes; Guinea Pigs; Hydrazines; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukocyte Count; Mercaptopurine; Prednisolone; Sheep

1963
HYDROXYMETHYLGLYOXAL BISGUANYLHYDRAZONE.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Hydrazines; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Spectrum Analysis

1963
[ATTEMPT AT TREATMENT OF HODGKIN'S DISEASE AND VARIOUS HEMATOSARCOMAS WITH 1-METHYL-2-P-ALLOPHANOYL-BENZYLHYDRAZINE HYDROBROMIDE].
    Revue francaise d'etudes cliniques et biologiques, 1964, Volume: 9

    Topics: Antineoplastic Agents; Hodgkin Disease; Humans; Hydrazines; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycosis Fungoides; Neoplasms; Sarcoma

1964
[RESULTS OF CLINICAL TESTS OF A NEW CYTOSTATIC SUBSTANCE FROM THE METHYLHYDRAZINE SERIES (NATULAN)].
    Medizinische Klinik, 1965, Jun-11, Volume: 60

    Topics: Antineoplastic Agents; Drug Therapy; Hodgkin Disease; Humans; Hydrazines; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Methylhydrazines; Plasmacytoma; Procarbazine

1965
[The effect of glyoxal-bis (guanylhydrazone) on transplanted mouse leukemia].
    Die Medizinische, 1959, Jul-25, Volume: No 29-30

    Topics: Animals; Glyoxal; Hydrazines; Leukemia; Leukemia, Experimental; Mice; Mitoguazone

1959
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cytarabine; Deoxycytidine; Drug Interactions; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrazines; Idarubicin; Irinotecan; Leukemia; Lymphoma; Sulfonamides; Topotecan

2008
Lethality to leukemia cell lines of DNA interstrand cross-links generated by Cloretazine derived alkylating species.
    Leukemia research, 2008, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cross-Linking Reagents; Cytosine; DNA; Ethane; Guanine; HL-60 Cells; Humans; Hydrazines; Leukemia; Mice; Sulfonamides; U937 Cells

2008
[Nucleic acid synthesis and cytostatic drug effect in pathological lymph node cells].
    Medizinische Klinik, 1966, Apr-22, Volume: 61, Issue:16

    Topics: Aged; Antineoplastic Agents; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Hodgkin Disease; Humans; Hydrazines; Hyperplasia; Leukemia; Lymph Nodes; Lymphadenitis; Lymphatic Diseases; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Male; Neoplasms; Nitrogen Mustard Compounds; Nucleosides; Prednisolone; RNA, Neoplasm; Thymidine; Tritium; Vinblastine

1966
[The tumor-inducing action of hydrazine].
    Zeitschrift fur Krebsforschung, 1967, Volume: 70, Issue:2

    Topics: Animals; Carcinogens; Child, Preschool; Female; Humans; Hydrazines; Isoniazid; Leukemia; Liver; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Mediastinum; Mice; Neoplasms, Experimental; Spleen

1967
[Cytostatic therapy of hemoblastoses and malignant tumors with a methylhydrazine derivative].
    Wiener klinische Wochenschrift, 1966, Dec-02, Volume: 78, Issue:48

    Topics: Adolescent; Adult; Aged; Bone Marrow Examination; Breast Neoplasms; Carcinoma, Bronchogenic; Female; Hodgkin Disease; Humans; Hydrazines; Kidney Neoplasms; Leukemia; Lymphadenitis; Lymphoma, Large B-Cell, Diffuse; Male; Melanoma; Middle Aged; Sarcoma, Synovial

1966
Current problems in the use of the oncolytic drugs.
    Acta geneticae medicae et gemellologiae, 1968, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; Fluorouracil; Gonadal Steroid Hormones; Hodgkin Disease; Humans; Hydrazines; Leukemia; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Mesenchymoma; Methotrexate; Multiple Myeloma; Nitrogen Mustard Compounds; Ovarian Neoplasms; Pregnancy; Prostatic Neoplasms; Steroids; Testicular Neoplasms; Urethane; Vinblastine; Vincristine; Wilms Tumor

1968
[Results of animal experiments on radiosensitization in partial or whole-body radiation].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1972

    Topics: Alkaloids; Animals; Antifungal Agents; Antineoplastic Agents; Ascites; Colchicine; Demecolcine; Hydrazines; Indicators and Reagents; Iron; Leukemia; Mice; Radiation-Sensitizing Agents; Riboflavin; Triacetin; Triglycerides; Urethane; Vitamin K

1972
[Personal experience on the chemotherapy of leukemias and hematosarcomas].
    Acta geneticae medicae et gemellologiae, 1968, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Drug Synergism; Hodgkin Disease; Humans; Hydrazines; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycosis Fungoides; Vinblastine; Vincristine

1968
[Results and current biological bases of therapy of malignant hemoreticulopathies].
    Studii si cercetari de medicina interna, 1971, Volume: 12, Issue:3

    Topics: Antineoplastic Agents; Chlorambucil; Cortisone; Cyclophosphamide; Humans; Hydrazines; Leukemia; Lymphoma; Mechlorethamine; Methotrexate; Plasmacytoma; Polycythemia; Vinblastine; Waldenstrom Macroglobulinemia

1971
[Therapy of malignant hemopathies].
    Praxis, 1966, Jun-16, Volume: 55, Issue:24

    Topics: Female; Hematologic Diseases; Humans; Hydrazines; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Multiple Myeloma; Prednisone

1966
[Induction of immune insufficiency in adult mice by the additive utilization of a non-specific stimulant of immune reactions and of immunosuppressive chemotherapy].
    Revue francaise d'etudes cliniques et biologiques, 1969, Volume: 14, Issue:9

    Topics: Animals; BCG Vaccine; Depression, Chemical; Drug Synergism; Female; Hydrazines; Immunity, Active; Immunochemistry; Immunosuppressive Agents; Leukemia; Mice; Transplantation Immunology

1969
Procarbazine hydrochloride in childhood cancer.
    The Journal of pediatrics, 1969, Volume: 75, Issue:5

    Topics: Adolescent; Adult; Antimetabolites; Child; Child, Preschool; Female; Hodgkin Disease; Humans; Hydrazines; Infant; Leukemia; Lymphoma, Non-Hodgkin; Male; Neoplasms

1969
Potential anticancer agents. I. Synthesis of some nitrogen mustard containing benzylidenehydrazides.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:1

    Topics: Animals; Benzene Derivatives; Carcinoma 256, Walker; Hydrazines; Leukemia; Leukemia L1210; Nitrogen Mustard Compounds

1968
Comparative carcinogenicity of N-isopropyl-alpha-(2-methylhydraziono)-p-toluamide. HCI (procarbazine hydrochloride), its degradation products, other hydrazines, and isonicotinic acid hydrazide.
    Journal of the National Cancer Institute, 1969, Volume: 42, Issue:2

    Topics: Amides; Animals; Azo Compounds; Carcinogens; Cystadenoma; Hydrazines; Isoniazid; Kidney Neoplasms; Leukemia; Lung Neoplasms; Male; Mice; Neoplasms, Experimental

1969
[Effect of a methylhydrazine derivative, Ro 4-6467, in Hodgkin's disease, in other malignant lymphomas and in leukemias].
    European journal of cancer, 1965, Volume: 1, Issue:1

    Topics: Adolescent; Adult; Aged; Female; Hodgkin Disease; Humans; Hydrazines; Leukemia; Lymphoma; Male; Middle Aged

1965
[Combinations and sequences of multiple chemotherapeutic compounds in leukemia and hematosarcoma].
    Semaine therapeutique, 1966, Volume: 42, Issue:10

    Topics: Antineoplastic Agents; Hodgkin Disease; Humans; Hydrazines; Leukemia; Prednisone; Triethylenemelamine; Vinblastine

1966