hydrazine has been researched along with Leukemia L 1210 in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (70.00) | 18.7374 |
| 1990's | 4 (10.00) | 18.2507 |
| 2000's | 8 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GOLDIN, A; SHELDON, DR; VENDITTI, JM | 1 |
| ADAMSON, RH; DAVIDSON, JD; DION, RL; LOO, TL | 1 |
| CHENG, CC; FRENCH, FA; NYBERG, WH; PODREBARAC, EG | 1 |
| ADAMSON, RH | 1 |
| Arlot-Bonnemains, Y; Aubin, S; Baudy-Floc'h, M; Bouget, K; Delcros, JG | 1 |
| Graczyk, J; Nawrot-Modranka, J; Ochocki, J | 1 |
| Arlot-Bonnemains, Y; Aubin, S; Baudy-Floc'h, M; Delcros, JG; Martin, B | 1 |
| Penketh, PG; Rice, KP; Sartorelli, AC; Shyam, K | 1 |
| Ishiguro, K; Penketh, PG; Sartorelli, AC; Seow, HA; Shyam, K | 1 |
| King, I; Li, Z; Liu, L; Song, BL; Zheng, LM | 1 |
| Marxer, A | 1 |
| Mihich, E | 1 |
| Golovinsky, E; Maneva, L; Pelova, R; Spassovska, N | 1 |
| Golovinsky, EV; Karaivanova, MH; Zakhariev, SG | 1 |
| Divo, AA; Loomis, RH; Penketh, PG; Rose, WC; Sartorelli, AC; Shyam, K | 1 |
| Furuta, T; Miyasaka, T; Sawada, S; Yaegashi, T; Yamaguchi, K; Yokokura, T | 1 |
| Auger, R; Beuneu, C; Guissani, A; Lemaire, G; Lepoivre, M; Löffler, M | 1 |
| Finch, RA; Penketh, PG; Sartorelli, AC; Shyam, K | 1 |
| Gutsche, W; Jungstand, W; Letsch, G; Schulze, W; Wohlrabe, K | 1 |
| Beisler, JA; Driscoll, JS; Peng, GW | 1 |
| Bois, C; Kozelka, J; Segal, E | 1 |
| Divo, AA; Loomis, RH; Patton, CL; Penketh, PG; Sartorelli, AC; Shyam, K | 1 |
| Cosby, LA; Furubayashi, R; Hrubiec, RT; Sartorelli, AC; Shyam, K | 2 |
| Cosby, LA; Sartorelli, AC; Shyam, K | 1 |
| Tran Ba Loc, P | 1 |
| Gold, J | 1 |
| Colvin, M; Thomson, M | 1 |
| Brian, WP | 1 |
| Connors, TA | 1 |
| Choquet, C; Crochet, MF; Florentin, I; Halle-Pannenko, O; Rosenkovitch, E | 1 |
| Caldes, G; Prescott, B | 1 |
| Florvall, L | 1 |
| Boykin, DW; Varma, RS | 1 |
| Ehrke, MJ; Mihich, E; Soucek, J | 1 |
| Deliwala, CV; Dhapalupur, MG; Sabnis, SS | 1 |
| Mihich, E; Mulhern, AI | 1 |
| Caldes, G; Lones, G; Prescott, B | 2 |
| Blanz, EJ; DoAmaral, JR; French, FA | 1 |
40 other study(ies) available for hydrazine and Leukemia L 1210
| Article | Year |
|---|---|
The antileukemic effectiveness of methylglyoxal bis(guanylhydrazone) in mice. Studies of cross-resistance and combination chemotherapy.
Topics: Animals; Antineoplastic Agents; Drug Therapy, Combination; Hydrazines; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Mitoguazone; Pyruvaldehyde | 1963 |
HYDROXYMETHYLGLYOXAL BISGUANYLHYDRAZONE.
Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Hydrazines; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Spectrum Analysis | 1963 |
STUDIES ON METHYLGLYOXAL BIS(GUANYLHYDRAZONE) ANALOGS. I. HOMOLOGS OF METHYLGLYOXAL BIS(GUANYLHYDRAZONE).
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Guanidines; Hydrazines; Leukemia L1210; Leukemia, Experimental; Mitoguazone; Neoplasms; Neoplasms, Experimental; Pharmacology; Pyruvaldehyde; Research; Sarcoma 180 | 1963 |
ACTIVITY OF CONGENERS OF HYDROXYUREA AGAINST ADVANCED LEUKEMIA L1210.
Topics: Animals; Guanidine; Guanidines; Hydrazines; Hydroxylamines; Hydroxyurea; Leukemia L1210; Mice; Pharmacology; Research; Selenium; Selenium Compounds; Thiourea; Urea; Urethane | 1965 |
Hydrazino-aza and N-azapeptoids with therapeutic potential as anticancer agents.
Topics: Animals; Antineoplastic Agents; Aza Compounds; Cell Line, Tumor; Hydrazines; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Peptoids | 2003 |
Phosphorohydrazines of 4-oxo-4H-1-benzopyran and 1-benzopyran-2,4-dione exhibit antitumor activity against L1210 leukemia.
Topics: Animals; Antineoplastic Agents; Chromones; Hydrazines; Lethal Dose 50; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Transplantation; Organophosphorus Compounds | 2004 |
Retro hydrazino-azapeptoids as peptidomimetics of proteasome inhibitors.
Topics: Animals; Antineoplastic Agents; Biochemistry; Cell Proliferation; Drug Screening Assays, Antitumor; Hydrazines; Inhibitory Concentration 50; Leukemia L1210; Mice; Molecular Mimicry; Peptoids; Protease Inhibitors; Proteasome Inhibitors; Tumor Cells, Cultured | 2005 |
Differential inhibition of cellular glutathione reductase activity by isocyanates generated from the antitumor prodrugs Cloretazine and BCNU.
Topics: Animals; Antineoplastic Agents; Carmustine; Enzyme Inhibitors; Glutathione; Glutathione Reductase; Humans; Hydrazines; Isocyanates; Leukemia L1210; Mice; Prodrugs; Sulfonamides | 2005 |
Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Survival; Comet Assay; Histones; Hydrazines; Leukemia L1210; Mice; O(6)-Methylguanine-DNA Methyltransferase; Phosphorylation; Prodrugs; Sulfonamides; Transfection | 2006 |
Anti-tumor efficacy of Cloretazine (VNP40101M) alone and in combination with fludarabine in murine tumor and human xenograft tumor models.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrazines; Injections, Intraperitoneal; Leukemia L1210; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Sulfonamides; Survival Analysis; Time Factors; Tumor Burden; Vidarabine; Weight Loss; Xenograft Model Antitumor Assays | 2007 |
A new bis-guanylhydrazone with antileukemic properties.
Topics: Animals; Antineoplastic Agents; Hydrazines; Leukemia L1210; Leukemia, Experimental; Lymphoma; Mice | 1967 |
Antileukemic action of new aromatic bisguanylhydrazone derivatives.
Topics: Animals; Antineoplastic Agents; Biguanides; Drug Synergism; Hydrazines; Leukemia L1210; Mice; Stilbamidines | 1967 |
Synthesis and biological activity of derivatives of hydrazinopyrimidines with carbonyl compounds.
Topics: Animals; Antineoplastic Agents; Bacteria; Hydrazines; Leukemia L1210; Mice; Mice, Inbred C57BL; Pyrimidines | 1984 |
Antitumor effect of N alpha-benzyloxycarbonyl-N,N-bis-(2-halogenethyl)-hydrazide derivatives of amino acids.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Hematopoietic System; Hydrazines; Leukemia L1210; Leukocyte Count; Melphalan; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats | 1980 |
Synthesis and evaluation of 1-acyl-1,2-bis(methylsulfonyl)-2-(2- chloroethyl)hydrazines as antineoplastic agents.
Topics: Acylation; Alkylation; Animals; Antineoplastic Agents; Drug Stability; Female; Glutathione; Hydrazines; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Sarcoma, Experimental; Structure-Activity Relationship; Sulfonamides | 1993 |
Chemical modification of antitumor alkaloids, 20(S)-camptothecin and 7-ethylcamptothecin: reaction of the E-lactone ring portion with hydrazine hydrate.
Topics: Animals; Camptothecin; Female; Hydrazines; Leukemia L1210; Mice | 1993 |
Indirect inhibition of mitochondrial dihydroorotate dehydrogenase activity by nitric oxide.
Topics: Animals; Antioxidants; Ascorbic Acid; Digitonin; Dihydroorotate Dehydrogenase; Electron Transport; Electron Transport Complex IV; Enzyme Inhibitors; Humans; Hydrazines; K562 Cells; Leukemia L1210; Leukemia-Lymphoma, Adult T-Cell; Macrophages; Mice; Mitochondria; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Orotic Acid; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Rats; Recombinant Proteins; Tumor Cells, Cultured | 2000 |
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-(methylamino)carbonylhydrazine (101M): a novel sulfonylhydrazine prodrug with broad-spectrum antineoplastic activity.
Topics: Animals; Antineoplastic Agents; Carmustine; Drug Screening Assays, Antitumor; Female; Humans; Hydrazines; Leukemia L1210; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Nitroso Compounds; Prodrugs; Xenograft Model Antitumor Assays | 2001 |
[Carbonyl derivatives of tilorone. Part 2: On the cancerostatic activity of carbonyl derivatives of tilorone (author's transl)].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Fluorenes; Hydrazines; Leukemia L1210; Mice; Rats; Tilorone | 1979 |
Potential antitumor agents: procarbazine analogs and other methylhydrazine derivatives.
Topics: Animals; Antineoplastic Agents; Hydrazines; Leukemia L1210; Mice; Monomethylhydrazine; Procarbazine; Structure-Activity Relationship | 1977 |
Cytotoxic activity of platinum (II) complexes with tri-n-butylphosphine. Crystal structure of the dinuclear hydrazine-bridged complex, cis,cis-[PtCl(PBu3n)2(mu-N2H4)PtCl(PBu3n) 2] (ClO4)2.2CHCl3.
Topics: Animals; Antineoplastic Agents; Crystallization; Hydrazines; Leukemia L1210; Magnetic Resonance Spectroscopy; Methanol; Methylene Chloride; Mice; Mice, Inbred DBA; Molecular Structure; Organometallic Compounds; Phosphines; Platinum; Solutions; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured; X-Ray Diffraction | 1992 |
Synthesis and evaluation of 1,2,2-tris(sulfonyl)hydrazines as antineoplastic and trypanocidal agents.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Female; Hydrazines; Leukemia L1210; Leukemia P388; Mice; Molecular Structure; Prodrugs; Sarcoma 180; Sulfones; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tumor Cells, Cultured | 1990 |
Synthesis and evaluation of 2-substituted 1-methyl-1-(4-tolylsulfonyl)hydrazines as antineoplastic agents.
Topics: Animals; Antineoplastic Agents; Cell Survival; Drug Evaluation, Preclinical; Hydrazines; Indicators and Reagents; Leukemia L1210; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Structure-Activity Relationship | 1986 |
1,2-bis(arylsulfonyl)hydrazines. 2. The influence of arylsulfonyl and aralkylsulfonyl substituents on antitumor and alkylating activity.
Topics: Alkylating Agents; Alkylation; Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Hydrazines; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship | 1986 |
Synthesis and evaluation of N,N'-bis(arylsulfonyl)hydrazines as antineoplastic agents.
Topics: Animals; Antineoplastic Agents; Hydrazines; Leukemia L1210; Mice; Mice, Inbred Strains; Structure-Activity Relationship; Sulfones | 1985 |
[Comparative study of the effects of thiocarbohydrazide and chemically modified deoxyribonucleic acids on reticulosarcoma ST4 and leukemia L 1210].
Topics: Animals; Antineoplastic Agents; DNA; Hydrazines; Leukemia L1210; Mice; Sarcoma, Experimental | 1966 |
Inhibition by hydrazine sulfate and various hydrazides, of in vivo growth of Walker 256 intramuscular carcinoma, B-16 melanoma, Murphy-Sturm lymphosarcoma and L-1210 solid leukemia.
Topics: Animals; Carcinoma 256, Walker; Cyclophosphamide; Female; Gluconeogenesis; Hydrazines; Leukemia L1210; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Male; Melanoma; Mice; Mitomycins; Neoplasm Transplantation; Phosphoenolpyruvate Carboxykinase (GTP); Pyridines; Rats; Sarcoma, Experimental; Transplantation, Homologous | 1973 |
Chemical oxidation of cyclophosphamide and 4-methylcyclophosphamide.
Topics: Aldehydes; Animals; Biological Assay; Chemical Phenomena; Chemistry; Chromatography, Gas; Cyclophosphamide; Dinitrophenols; Female; Hydrazines; Ketones; Leukemia L1210; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Oxidation-Reduction; Transplantation, Homologous | 1974 |
Synthesis of derivatives of N,N-dimethylhydrazine and their physiological activities.
Topics: Animals; Hydrazines; Leukemia L1210; Malaria; Mice; Mice, Inbred Strains; Structure-Activity Relationship; Time Factors | 1971 |
An outline of cancer chemotherapy.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Asparaginase; Breast Neoplasms; Cells, Cultured; Colonic Neoplasms; Cricetinae; DNA, Neoplasm; Humans; Hydrazines; Hydroxyurea; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Mitomycins; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Rats; Ribonucleotides; Ribosomes; RNA, Neoplasm; Transplantation, Heterologous | 1971 |
[Comparison of the effects of the total irradiation-methylhydrazine combination and total irradiation alone for the eradication of transplanted L 1210 leukemia treated by adoptive immunotherapy].
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Bone Marrow Transplantation; Female; Hydrazines; Leukemia L1210; Mice; Neoplasm Transplantation | 1966 |
Potential antitumor agents. Derivatives of 2-hydrazino-5-nitropyridine.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Hydrazines; Leukemia L1210; Neoplasms, Experimental; Pyridines; Rats; Sarcoma 180 | 1970 |
Some antitumor agents derived from benzaldehyde nitrogen mustards.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; Hydrazines; Leukemia L1210; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Triazoles | 1970 |
Benzylidene hydrazides as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Hydrazines; Leukemia L1210; Mice | 1970 |
Effects of 4,4'-diacetyldiphenylurea-bis-(guanylhydrazone) on the incorporation of precursors into nucleic acid and protein of leukemia L1210.
Topics: Animals; Carbon Isotopes; Culture Techniques; Depression, Chemical; DNA Nucleotidyltransferases; DNA, Neoplasm; Guanine; Hydrazines; Injections, Intraperitoneal; Leukemia L1210; Mice; Neoplasm Proteins; Phenylalanine; RNA, Neoplasm; Thymidine; Urea; Uridine | 1970 |
Potential anticancer agents. I. Synthesis of some nitrogen mustard containing benzylidenehydrazides.
Topics: Animals; Benzene Derivatives; Carcinoma 256, Walker; Hydrazines; Leukemia; Leukemia L1210; Nitrogen Mustard Compounds | 1968 |
Effects of 4,4'-diacetyl-diphenyl-urea-bis(guanylhydrazone) on leukemia L1210.
Topics: Animals; Antineoplastic Agents; Cytarabine; Drug Synergism; Female; Hydrazines; Injections, Intraperitoneal; Injections, Subcutaneous; Leukemia L1210; Male; Mice; Time Factors; Urea | 1968 |
Bis-hydrazones of 1,4-diaminopiperazine as potential antimicrobial agents.
Topics: Adenocarcinoma; Aldehydes; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Carcinoma 256, Walker; Cryptococcus; Depression, Chemical; Histoplasma; Hydrazines; Leukemia L1210; Mice; Piperazines; Staphylococcus | 1968 |
1,4-phthalazinediyldihydrazones ad potential chemotherapeutic agents.
Topics: Animals; Antibiotics, Antineoplastic; Antifungal Agents; Carcinoma 256, Walker; Cryptococcus; Heterocyclic Compounds; Histoplasma; Hydrazines; Leukemia L1210; Rats; Staphylococcus | 1968 |
Antimalarial activity of guanylhydrazone salts of aromatic ketones. I. Primary search for active substituent patterns.
Topics: Animals; Antimalarials; Benzophenones; Chemical Phenomena; Chemistry; Guanidines; Hydrazines; Leukemia L1210; Mice | 1969 |