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hydralazine and Vasculitis

hydralazine has been researched along with Vasculitis in 13 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Vasculitis: Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.

Research Excerpts

ExcerptRelevanceReference
"Hydralazine is an antihypertensive medication that has been associated with drug-induced lupus erythematosus (DIL) as well as ANCA-associated vasculitis (AAV)."7.88Hydralazine-associated vasculitis: Overlapping features of drug-induced lupus and vasculitis. ( Kumar, B; Lenert, P; Strouse, J; Suneja, M; Swee, M, 2018)
"We report a rare case of Hydralazine-induced ANCA associated glomerulonephritis with alveolar hemorrhage in the setting of acute Clostridium Difficile Infection."7.83Hydralazine-Induced ANCA Vasculitis in the Setting of Acute Clostridium Difficile Infection. ( Cucu, DF; El Meligy, A; Rasla, S, 2016)
"We have previously found that T lymphocytes are essential for development of angiotensin II-induced hypertension; however, the mechanisms responsible for T-cell activation in hypertension remain undefined."7.76Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. ( Gordon, FJ; Guzik, TJ; Harrison, DG; Lob, HE; Marvar, PJ; McCann, LA; Thabet, SR; Weyand, C, 2010)
"Renal cell carcinoma and hydralazine drug therapy has each been reported as rare associations with pauci-immune renal vasculitis."7.72P-ANCA positive renal vasculitis in association with renal cell carcinoma and prolonged hydralazine therapy. ( Jeffrey, RF; Leeds, J; Norris, JH, 2003)
" The present study was aimed to investigate distribution of anti-lactoferrin antibodies in systemic lupus erythematosus, the hydralazine-induced SLE-like syndrome, and in rheumatoid arthritis compared to RA complicated with vasculitis."7.69Occurrence of anti-lactoferrin antibodies in patients with systemic lupus erythematosus, hydralazine-induced lupus, and rheumatoid arthritis. ( Hultquist, R; Nässberger, L; Sturfelt, G, 1994)
" Hoarseness developed in a 60-year-old man that was secondary to ulcerated lesions, which involved the epiglottis and aryteno-epiglottic folds, with serologic evidence of SLE after he had been treated with hydralazine for six months."7.67Hydralazine hoarseness. A new appearance of drug-induced systemic lupus erythematosus. ( Forouhar, FA; Weiser, GA; White, WB, 1984)
"Hydralazine is an antihypertensive medication that has been associated with drug-induced lupus erythematosus (DIL) as well as ANCA-associated vasculitis (AAV)."3.88Hydralazine-associated vasculitis: Overlapping features of drug-induced lupus and vasculitis. ( Kumar, B; Lenert, P; Strouse, J; Suneja, M; Swee, M, 2018)
"Hydralazine-induced small vessel vasculitis is a rare entity with a limited number of cases reported in the dermatologic literature."3.85Hydralazine-associated cutaneous casculitis presenting with aerodigestive tract involvement. ( Harp, J; Horowitz, J; Levin, LE; Magro, C, 2017)
"We report a rare case of Hydralazine-induced ANCA associated glomerulonephritis with alveolar hemorrhage in the setting of acute Clostridium Difficile Infection."3.83Hydralazine-Induced ANCA Vasculitis in the Setting of Acute Clostridium Difficile Infection. ( Cucu, DF; El Meligy, A; Rasla, S, 2016)
"We have previously found that T lymphocytes are essential for development of angiotensin II-induced hypertension; however, the mechanisms responsible for T-cell activation in hypertension remain undefined."3.76Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. ( Gordon, FJ; Guzik, TJ; Harrison, DG; Lob, HE; Marvar, PJ; McCann, LA; Thabet, SR; Weyand, C, 2010)
"Renal cell carcinoma and hydralazine drug therapy has each been reported as rare associations with pauci-immune renal vasculitis."3.72P-ANCA positive renal vasculitis in association with renal cell carcinoma and prolonged hydralazine therapy. ( Jeffrey, RF; Leeds, J; Norris, JH, 2003)
"In this study, we determined the prevalence of exposure to hydralazine, propylthiouracil, and other drugs previously implicated in APV among 30 patients with vasculitis and the highest titers of anti-MPO antibodies newly detected in our laboratory between 1994 and 1998."3.70Drug-associated antineutrophil cytoplasmic antibody-positive vasculitis: prevalence among patients with high titers of antimyeloperoxidase antibodies. ( Choi, HK; Merkel, PA; Niles, JL; Walker, AM, 2000)
" The present study was aimed to investigate distribution of anti-lactoferrin antibodies in systemic lupus erythematosus, the hydralazine-induced SLE-like syndrome, and in rheumatoid arthritis compared to RA complicated with vasculitis."3.69Occurrence of anti-lactoferrin antibodies in patients with systemic lupus erythematosus, hydralazine-induced lupus, and rheumatoid arthritis. ( Hultquist, R; Nässberger, L; Sturfelt, G, 1994)
" Hoarseness developed in a 60-year-old man that was secondary to ulcerated lesions, which involved the epiglottis and aryteno-epiglottic folds, with serologic evidence of SLE after he had been treated with hydralazine for six months."3.67Hydralazine hoarseness. A new appearance of drug-induced systemic lupus erythematosus. ( Forouhar, FA; Weiser, GA; White, WB, 1984)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levin, LE1
Magro, C1
Horowitz, J1
Harp, J1
Kumar, B1
Strouse, J1
Swee, M1
Lenert, P1
Suneja, M1
Rasla, S1
El Meligy, A1
Cucu, DF1
Marvar, PJ1
Thabet, SR1
Guzik, TJ1
Lob, HE1
McCann, LA1
Weyand, C1
Gordon, FJ1
Harrison, DG1
Norris, JH1
Leeds, J1
Jeffrey, RF1
Weiser, GA1
Forouhar, FA1
White, WB1
Macleod, WN1
Nässberger, L1
Hultquist, R1
Sturfelt, G1
Cambridge, G1
Wallace, H1
Bernstein, RM1
Leaker, B1
Choi, HK1
Merkel, PA1
Walker, AM1
Niles, JL1
Martinez-Vea, A1
Ferrer, I1
Carcía, C1
Mayayo, E1
Oliver, JA1
Richart, C1
Stevens, MB1
Doherty, M1
Maddison, PJ1
Grey, RH1

Reviews

1 review available for hydralazine and Vasculitis

ArticleYear
Connective tissue disease in the elderly.
    Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1

    Topics: Aged; Connective Tissue Diseases; Dermatomyositis; Female; Giant Cell Arteritis; Humans; Hydralazine

1986

Other Studies

12 other studies available for hydralazine and Vasculitis

ArticleYear
Hydralazine-associated cutaneous casculitis presenting with aerodigestive tract involvement.
    Cutis, 2017, Volume: 99, Issue:5

    Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Diagnosis, Differential; Fema

2017
Hydralazine-associated vasculitis: Overlapping features of drug-induced lupus and vasculitis.
    Seminars in arthritis and rheumatism, 2018, Volume: 48, Issue:2

    Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Female; Humans; Hydralazine;

2018
Hydralazine-Induced ANCA Vasculitis in the Setting of Acute Clostridium Difficile Infection.
    Rhode Island medical journal (2013), 2016, Nov-01, Volume: 99, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Clos

2016
Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension.
    Circulation research, 2010, Jul-23, Volume: 107, Issue:2

    Topics: Administration, Oral; Adoptive Transfer; Angiotensin II; Animals; Antihypertensive Agents; Blood Pre

2010
P-ANCA positive renal vasculitis in association with renal cell carcinoma and prolonged hydralazine therapy.
    Renal failure, 2003, Volume: 25, Issue:2

    Topics: Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Carcinoma, Renal Cell; Humans; Hydr

2003
Hydralazine hoarseness. A new appearance of drug-induced systemic lupus erythematosus.
    Archives of internal medicine, 1984, Volume: 144, Issue:11

    Topics: Epiglottis; Hoarseness; Humans; Hydralazine; Laryngeal Diseases; Lupus Erythematosus, Systemic; Male

1984
Anaemia in the hydrallazine-induced Lupus syndrome.
    Scottish medical journal, 1983, Volume: 28, Issue:2

    Topics: Aged; Anemia; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Syndrome; Vasculitis

1983
Occurrence of anti-lactoferrin antibodies in patients with systemic lupus erythematosus, hydralazine-induced lupus, and rheumatoid arthritis.
    Scandinavian journal of rheumatology, 1994, Volume: 23, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Female; Humans; H

1994
Autoantibodies to myeloperoxidase in idiopathic and drug-induced systemic lupus erythematosus and vasculitis.
    British journal of rheumatology, 1994, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic; Antibody Specificity; Autoantibodie

1994
Drug-associated antineutrophil cytoplasmic antibody-positive vasculitis: prevalence among patients with high titers of antimyeloperoxidase antibodies.
    Arthritis and rheumatism, 2000, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Antibodies; Antibodies, Antineutrophil Cyto

2000
Systemic vasculitis resembling periarteritis nodosa in the lupus-like syndrome induced by hydralazine.
    American journal of nephrology, 1987, Volume: 7, Issue:1

    Topics: Adult; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Polyarteritis Nodosa; Vasculitis

1987
Hydralazine induced lupus syndrome with eye disease.
    British medical journal (Clinical research ed.), 1985, Mar-02, Volume: 290, Issue:6469

    Topics: Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Middle Aged; Retinitis; Sy

1985