Page last updated: 2024-10-28

hydralazine and Uremia

hydralazine has been researched along with Uremia in 23 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Treatment with losartan, captopril, and the TRx prevented the rhEPO-induced increased in systolic BP."1.33Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin. ( Agharazii, M; Larivière, R; Lebel, M; Rodrigue, ME, 2006)
"Uremia was induced in male Spraugue Dawley rats by 5/6 nephrectomy."1.32Gene expression in uremic left ventricular hypertrophy: effects of hypertension and anemia. ( Chang, SL; Draksharapu, A; Mak, RH; Pak, YK, 2004)
"The anipamil-treated group exhibited significantly greater protection of renal function than did the hydralazine-treated group for the same level of blood pressure control."1.28Effect of long-acting calcium entry blocker (anipamil) on blood pressure, renal function and survival of uremic rats. ( Chan, L; Jarusiripipat, C; Schrier, RW; Shapiro, JI, 1992)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199018 (78.26)18.7374
1990's2 (8.70)18.2507
2000's3 (13.04)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MCQUIGGAN, MC1
OLIVER, WJ1
LITTLER, ER1
CERNY, JC1
Dikow, R1
Kihm, LP1
Zeier, M1
Kapitza, J1
Törnig, J1
Amann, K2
Tiefenbacher, C1
Ritz, E2
Mak, RH1
Chang, SL1
Draksharapu, A1
Pak, YK1
Lebel, M1
Rodrigue, ME1
Agharazii, M1
Larivière, R1
Kotler, MN1
Segal, BL1
Grim, CE1
Neusüss, R1
Irzyniec, T1
Wiest, G1
Mall, G1
Mogensen, CE1
Teehan, BP1
Smith, LJ1
Sigler, MH1
Gilgore, GS1
Schleifer, CR1
Jarusiripipat, C1
Chan, L1
Shapiro, JI1
Schrier, RW1
Abella, R1
Blondeel, NJ1
Roguska, J1
Walker, C1
Simon, NM1
Del Greco, F1
Freis, ED1
Onesti, G2
Finnerty, FA1
Reidenberg, MM1
Acchiardo, SR1
Black, WD1
Britt, L1
McKeown, JW1
Johnson, JG1
Hatch, F1
Kim, KE1
Swartz, C1
Moser, M1
Rahill, WJ1
Rubin, MI1
Hirasawa, Y1
Omori, H1
Takahashi, Y1
Imai, H1
Takahashi, S1
Jameson, S1
Hutchings, RH1
Hickman, R1
Scribner, BH1

Reviews

3 reviews available for hydralazine and Uremia

ArticleYear
Effectiveness of drug therapy in hypertension: present status. A review.
    Circulation research, 1971, Volume: 28, Issue:5

    Topics: Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Eye Diseases; Ganglionic Block

1971
Kidney disease and drug metabolism.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Aminosalicylic Acids; Cholinesterase Inhibitors; Enzyme Activation; Humans; Hydralazine; Hydrolysis;

1974
Treatment of "hypertensive encephalopathy" (accelerated hypertension). II.
    American heart journal, 1969, Volume: 77, Issue:5

    Topics: Antihypertensive Agents; Diazoxide; Glomerulonephritis; Guanethidine; Humans; Hydralazine; Hypertens

1969

Other Studies

20 other studies available for hydralazine and Uremia

ArticleYear
HEMOLYTIC UREMIC SYNDROME.
    JAMA, 1965, Mar-08, Volume: 191

    Topics: Acute Kidney Injury; Anemia, Hemolytic; Child; Diagnosis; Dialysis; Diarrhea; Drug Therapy; Glomerul

1965
Increased infarct size in uremic rats: reduced ischemia tolerance?
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:6

    Topics: Animals; Body Weight; Coronary Vessels; Heart Ventricles; Hydralazine; Imidazoles; Ischemia; Male; M

2004
Gene expression in uremic left ventricular hypertrophy: effects of hypertension and anemia.
    Experimental & molecular medicine, 2004, Jun-30, Volume: 36, Issue:3

    Topics: Actins; Anemia; Animals; Atrial Natriuretic Factor; Erythropoietin; Gene Expression; Heart Ventricle

2004
Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin.
    American journal of hypertension, 2006, Volume: 19, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihype

2006
The inflamed heart: pericarditis in the elderly.
    Geriatrics, 1980, Volume: 35, Issue:1

    Topics: Aged; Cardiac Tamponade; Daunorubicin; Echocardiography; Heart Neoplasms; Humans; Hydralazine; Myoca

1980
Management of malignant hypertension.
    Comprehensive therapy, 1980, Volume: 6, Issue:5

    Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Drug

1980
Changes of vascular architecture independent of blood pressure in experimental uremia.
    American journal of hypertension, 1995, Volume: 8, Issue:4 Pt 1

    Topics: Animals; Aorta, Abdominal; Blood Pressure; Blood Vessels; Body Weight; Capillaries; Furosemide; Hydr

1995
Diabetes and hypertension.
    Lancet (London, England), 1979, Feb-17, Volume: 1, Issue:8112

    Topics: Blood Pressure; Diabetes Mellitus; Diabetic Nephropathies; Furosemide; Glomerular Filtration Rate; H

1979
Plasma pyridoxal-5'-phosphate levels and clinical correlations in chronic hemodialysis patients.
    The American journal of clinical nutrition, 1978, Volume: 31, Issue:10

    Topics: Adult; Humans; Hydralazine; Pyridoxal Phosphate; Pyridoxine; Renal Dialysis; Uremia; Vitamin B 6 Def

1978
Effect of long-acting calcium entry blocker (anipamil) on blood pressure, renal function and survival of uremic rats.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Hydralazine; Kidney; Male; Nephrecto

1992
Management of renal hypertension complicated by renal insufficiency.
    Lancet (London, England), 1967, Oct-07, Volume: 2, Issue:7519

    Topics: Blood Urea Nitrogen; Chlorothiazide; Guanethidine; Humans; Hydralazine; Hypertension, Malignant; Met

1967
Periodic dialysis in terminal uremia.
    JAMA, 1967, Feb-06, Volume: 199, Issue:6

    Topics: Adolescent; Adult; Anemia; Arthritis; Child; Female; Gastrointestinal Hemorrhage; Glaucoma; Glomerul

1967
Dialysis and volume control.
    Postgraduate medicine, 1974, Volume: 56, Issue:5

    Topics: Humans; Hydralazine; Hypertension; Minoxidil; Nephrectomy; Propranolol; Renal Dialysis; Sodium; Ultr

1974
Aggressive drug therapy in accelerated hypertension.
    The American journal of nursing, 1974, Volume: 74, Issue:12

    Topics: Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Ferr

1974
Experience with hemodialysis and renal transplantation in patients with malignant hypertension.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1974, Issue:4

    Topics: Acute Kidney Injury; Adult; Brain Diseases; Diazoxide; Diet Therapy; Female; Follow-Up Studies; Furo

1974
Problems in therapy for the hypertensive patient.
    Geriatrics, 1973, Volume: 28, Issue:3

    Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic

1973
Hypertension in infantile polycystic renal disease. The importance of early recognition and treatment of severe hypertension in polycystic renal disease.
    Clinical pediatrics, 1972, Volume: 11, Issue:4

    Topics: Aluminum; Child, Preschool; Glomerular Filtration Rate; Humans; Hydralazine; Hydroxides; Hypertensio

1972
[Chronic kidney failure].
    Naika. Internal medicine, 1971, Volume: 27, Issue:6

    Topics: Adult; Blood Urea Nitrogen; Diet Therapy; Dihydroxyphenylalanine; Humans; Hydralazine; Hypertension,

1971
[Effects of Inderal in the treatment of uremic hypertension].
    Nordisk medicin, 1971, Nov-08, Volume: 86, Issue:44

    Topics: Adult; Allopurinol; Diabetic Coma; Drug Combinations; Drug Interactions; Female; Humans; Hydralazine

1971
Chronic hemodialysis in a pre-adolescent.
    Pediatrics, 1966, Volume: 37, Issue:1

    Topics: Adolescent; Child; Diet, Sodium-Restricted; Female; Glomerulonephritis; Hematocrit; Humans; Hydralaz

1966