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hydralazine and Tachycardia

hydralazine has been researched along with Tachycardia in 23 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Research Excerpts

ExcerptRelevanceReference
"To assess the electrophysiological and antiarrhythmic effects of pharmacological load manipulation by an angiotensin converting enzyme (ACE) inhibitor (captopril) and a direct vasodilator (hydralazine plus isosorbide mononitrate) in patients with inducible ventricular tachycardia and impaired left ventricular function."9.07Comparative electrophysiological effects of captopril or hydralazine combined with nitrate in patients with left ventricular dysfunction and inducible ventricular tachycardia. ( Bashir, Y; Camm, AJ; Gibson, S; O'Nunain, S; Paul, VE; Sneddon, JF; Ward, DE, 1992)
"The antihypertensive efficacy and safety of IV labetalol were evaluated and compared with the efficacy and safety of IV hydralazine in the treatment of postoperative hypertension."9.06Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension. ( Dimich, I; Gabrielson, G; Kaplan, JA; Lingham, R; Singh, PP, 1989)
"This study aims to characterize the development of tachycardia after intravenous hydralazine administration during Phase I recovery."7.88Incidence, Course, and Characteristics of Hydralazine-Associated Tachycardia During Phase I Postanesthesia Recovery. ( Loken, BL; Oyen, LJ; Sebesta, HM; Shirk Marienau, M; Smith, JL; Sprung, J; Weingarten, TN, 2018)
"The role of the sympatho-adrenal system in the production of tachycardia accompanying the hypotensive response to hydralazine was studied in urethane-anesthetized rats subjected to previous bilateral adrenal demedullation or to pretreatment with 6-hydroxydopamine and compared with intact control animals."7.67Role of the sympatho-adrenal system in the reflex tachycardia produced by hydralazine in the anesthetized rat. ( García-Márquez, F; Vidrio, H, 1986)
"Supine and upright hemodynamic measurements were performed in 10 patients with chronic congestive heart failure, before and during vasodilator therapy with hydralazine and isosorbide dinitrate."7.66Postural hypotension and tachycardia during hydralazine--isosorbide dinitrate therapy for chronic heart failure. ( Haughom, F; Kramer, B; Massie, B, 1981)
"The correlation between hydralazine-induced tachycardia and overall cardiovascular reactivity to sympathetic stimulation was explored in 50 normal subjects."7.66Hydralazine tachycardia and sympathetic cardiovascular reactivity in normal subjects. ( Tena, I; Vidrio, H, 1980)
"Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates."7.66Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978)
"Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats."5.43Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016)
"Propranolol was demonstrated to block hydralazine-induced increases in serum renin activity in genetically hypertensive rats."5.25Altered renin release and propranolol potentiation of vasodilatory drug hypotension. ( Keeton, K; Pettinger, WA, 1975)
"To assess the electrophysiological and antiarrhythmic effects of pharmacological load manipulation by an angiotensin converting enzyme (ACE) inhibitor (captopril) and a direct vasodilator (hydralazine plus isosorbide mononitrate) in patients with inducible ventricular tachycardia and impaired left ventricular function."5.07Comparative electrophysiological effects of captopril or hydralazine combined with nitrate in patients with left ventricular dysfunction and inducible ventricular tachycardia. ( Bashir, Y; Camm, AJ; Gibson, S; O'Nunain, S; Paul, VE; Sneddon, JF; Ward, DE, 1992)
"The antihypertensive efficacy and safety of IV labetalol were evaluated and compared with the efficacy and safety of IV hydralazine in the treatment of postoperative hypertension."5.06Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension. ( Dimich, I; Gabrielson, G; Kaplan, JA; Lingham, R; Singh, PP, 1989)
"The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy."4.98Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018)
"This study aims to characterize the development of tachycardia after intravenous hydralazine administration during Phase I recovery."3.88Incidence, Course, and Characteristics of Hydralazine-Associated Tachycardia During Phase I Postanesthesia Recovery. ( Loken, BL; Oyen, LJ; Sebesta, HM; Shirk Marienau, M; Smith, JL; Sprung, J; Weingarten, TN, 2018)
"Azelnidipine suppressed cardiac hypertrophy, fibrosis, NADPH oxidase and superoxide in spSHRs more potently than amlodipine, and was associated with lower heart rates than amlodipine."3.73Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis. ( Ito, T; Kataoka, K; Kim-Mitsuyama, S; Lai, ZF; Ogawa, H; Tanaka, T; Tokutomi, Y; Yamamoto, E; Yamashita, T, 2006)
"Hydralazine (H) induces hypotension accompanied by cardiac stimulation due to activation of the arterial baroreflex."3.69Patterns of heart rate responses to hydralazine in normotensive and hypertensive rats. ( Vidrio, H, 1996)
"The role of the sympatho-adrenal system in the production of tachycardia accompanying the hypotensive response to hydralazine was studied in urethane-anesthetized rats subjected to previous bilateral adrenal demedullation or to pretreatment with 6-hydroxydopamine and compared with intact control animals."3.67Role of the sympatho-adrenal system in the reflex tachycardia produced by hydralazine in the anesthetized rat. ( García-Márquez, F; Vidrio, H, 1986)
"Supine and upright hemodynamic measurements were performed in 10 patients with chronic congestive heart failure, before and during vasodilator therapy with hydralazine and isosorbide dinitrate."3.66Postural hypotension and tachycardia during hydralazine--isosorbide dinitrate therapy for chronic heart failure. ( Haughom, F; Kramer, B; Massie, B, 1981)
"The correlation between hydralazine-induced tachycardia and overall cardiovascular reactivity to sympathetic stimulation was explored in 50 normal subjects."3.66Hydralazine tachycardia and sympathetic cardiovascular reactivity in normal subjects. ( Tena, I; Vidrio, H, 1980)
"Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates."3.66Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978)
"Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats."1.43Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016)
"Propranolol was demonstrated to block hydralazine-induced increases in serum renin activity in genetically hypertensive rats."1.25Altered renin release and propranolol potentiation of vasodilatory drug hypotension. ( Keeton, K; Pettinger, WA, 1975)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199015 (65.22)18.7374
1990's3 (13.04)18.2507
2000's1 (4.35)29.6817
2010's4 (17.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sridharan, K1
Sequeira, RP1
Weingarten, TN1
Loken, BL1
Smith, JL1
Sebesta, HM1
Shirk Marienau, M1
Oyen, LJ1
Sprung, J1
Shih, CC1
Hii, HP1
Tsao, CM1
Chen, SJ1
Ka, SM1
Liao, MH1
Wu, CC1
Cohn, JN1
McInnes, GT1
Shepherd, AM1
Yamamoto, E1
Lai, ZF1
Yamashita, T1
Tanaka, T1
Kataoka, K1
Tokutomi, Y1
Ito, T1
Ogawa, H1
Kim-Mitsuyama, S1
Kubo, T1
Yamashita, M1
Misu, Y1
Massie, B1
Kramer, B1
Haughom, F1
Heer, KR1
Davies, J1
MacArthur, CG1
Vidrio, H3
Tena, I1
Pettinger, WA1
Keeton, K1
Penhall, RK1
Frewin, DB1
Laslett, LJ1
DeMaria, AN1
Amsterdam, EA1
Mason, DT1
Munoz, AI1
Baralt, JF1
Melendez, MT1
Bashir, Y1
Sneddon, JF1
O'Nunain, S1
Paul, VE1
Gibson, S1
Ward, DE1
Camm, AJ1
Farker, K1
Henschel, L1
Marschner, JP1
Reimann, I1
Volkmann, H1
Hoffmann, A1
Dimich, I1
Lingham, R1
Gabrielson, G1
Singh, PP1
Kaplan, JA1
García-Márquez, F1
Belic, N1
Talano, JV1
Lagrue, G1
Weil, B1
Buisson, C1
Katila, M1
Frick, MH1
Gupta, KP1
Bhargava, KP1
Demers, L1
Gauthier, P1

Reviews

2 reviews available for hydralazine and Tachycardia

ArticleYear
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:9

    Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy

2018
Direct-acting vasodilators.
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:9

    Topics: Antihypertensive Agents; Hirsutism; Humans; Hydralazine; Hypertension; Minoxidil; Tachycardia; Treat

2011

Trials

3 trials available for hydralazine and Tachycardia

ArticleYear
Comparative electrophysiological effects of captopril or hydralazine combined with nitrate in patients with left ventricular dysfunction and inducible ventricular tachycardia.
    British heart journal, 1992, Volume: 67, Issue:5

    Topics: Aged; Captopril; Drug Combinations; Electrocardiography; Electrophysiology; Female; Heart; Hemodynam

1992
Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension.
    Journal of clinical anesthesia, 1989, Volume: 1, Issue:3

    Topics: Aged; Female; Hemodynamics; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Postope

1989
Combined dihydralazine and propranolol in the treatment of hypertension.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 4, Issue:1

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Female; Guanidines; Humans; Hydralazine; Hype

1970

Other Studies

18 other studies available for hydralazine and Tachycardia

ArticleYear
Incidence, Course, and Characteristics of Hydralazine-Associated Tachycardia During Phase I Postanesthesia Recovery.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2018, Volume: 33, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anesthesia Recovery Period; Antihypertensive Agents; Fe

2018
Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Acidosis; Animals; Bicarbonates; Biomarkers; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA

2016
Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis.
    Journal of hypertension, 2006, Volume: 24, Issue:10

    Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Cardiomegaly; Dihydropyridines; Endomyocardial Fibros

2006
Effects of beta blocking agents on the cardiovascular action of hydralazine in conscious rats.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Heart Rate; Hydralazine; Male; Rats; Rats, Inb

1981
Postural hypotension and tachycardia during hydralazine--isosorbide dinitrate therapy for chronic heart failure.
    Circulation, 1981, Volume: 63, Issue:3

    Topics: Heart Failure; Hemodynamics; Humans; Hydralazine; Hypotension, Orthostatic; Isosorbide Dinitrate; Lo

1981
The effect of hydralazine on arrhythmias in congestive cardiomyopathy.
    International journal of cardiology, 1981, Volume: 1, Issue:2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Cardiomyopathies; Female; Heart Failure; Heart Ra

1981
Hydralazine tachycardia and sympathetic cardiovascular reactivity in normal subjects.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:5

    Topics: Acetylation; Adolescent; Adult; Blood Pressure; Female; Heart Rate; Humans; Hydralazine; Male; Refle

1980
Patterns of heart rate responses to hydralazine in normotensive and hypertensive rats.
    Archives of medical research, 1996,Autumn, Volume: 27, Issue:3

    Topics: Animals; Antihypertensive Agents; Baroreflex; Bradycardia; Female; Heart Rate; Hydralazine; Hyperten

1996
Altered renin release and propranolol potentiation of vasodilatory drug hypotension.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:2

    Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Depression, Chemical; Dose-Response

1975
Sinus tachycardis in a hypertensive patient: drug withdrawal phenomenon?
    The Medical journal of Australia, 1977, Nov-19, Volume: 2, Issue:21

    Topics: Arrhythmia, Sinus; Female; Humans; Hydralazine; Hypertension; Middle Aged; Propranolol; Substance Wi

1977
Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy.
    Archives of internal medicine, 1978, Volume: 138, Issue:5

    Topics: Aged; Coronary Disease; Digitalis Glycosides; Female; Furosemide; Heart Failure; Humans; Hydralazine

1978
Arterial hypertension in infants with hydronephrosis. Report of six cases.
    American journal of diseases of children (1960), 1977, Volume: 131, Issue:1

    Topics: Blood Pressure; Female; Humans; Hydralazine; Hydronephrosis; Hypertension, Renal; Infant; Infant, Ne

1977
Investigations into a new antiarrhythmic substance Z-2-amino-5-chlor-benzophenon-amidin-hydralazin in humans.
    International journal of clinical pharmacology, therapy, and toxicology, 1992, Volume: 30, Issue:11

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Humans; Hydralazine; Injections, Intravenous; Intestin

1992
Role of the sympatho-adrenal system in the reflex tachycardia produced by hydralazine in the anesthetized rat.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:1

    Topics: Adrenal Glands; Adrenal Medulla; Anesthesia; Animals; Atropine; Blood Pressure; Heart Rate; Hydralaz

1986
Current concepts in sick sinus syndrome. II. ECG manifestation and diagnostic and therapeutic approaches.
    Archives of internal medicine, 1985, Volume: 145, Issue:4

    Topics: Atrial Fibrillation; Atropine; Bradycardia; Cardiac Pacing, Artificial; Electric Stimulation; Electr

1985
[General principles of antihypertensive treatment].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1974, Feb-14, Volume: 50, Issue:8

    Topics: Antihypertensive Agents; Cardiac Output; Clonidine; Follow-Up Studies; Ganglionic Blockers; Guanethi

1974
Mechanism of tachycardia induced by intracerebroventricular injection of hydrallazine (1-hydrazinophthalazine).
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:1

    Topics: Animals; Blood Pressure; Carotid Sinus; Cordotomy; Denervation; Dogs; Electrocardiography; Heart; He

1965
[Absence of direct effect of hydralazine on the heart rate].
    Revue canadienne de biologie, 1968, Volume: 27, Issue:2

    Topics: Animals; Dogs; Electrocardiography; Heart Rate; Hydralazine; Injections, Intra-Arterial; Tachycardia

1968
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