hydralazine has been researched along with Syndrome in 36 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is the second case report of hydralazine induced Sweet's syndrome and lupus erythematosus." | 8.78 | Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature. ( Franz, T; Medsger, TA; Ramsey-Goldman, R; Solano, FX, 1990) |
| "The collagen-like syndrome was induced in rats by hydralazine application during 5 months." | 7.67 | Glucose tolerance in rats with hydralazine-induced collagen-like syndrome. ( Jendryczko, A; Kucharz, E, 1984) |
| "LE-positive collagen-like syndrome was produced in rats with chronic hydralazine treatment." | 7.67 | Blood histamine level in rats with hydralazine-induced collagen-like syndrome. Short communication. ( Jendryczko, A; Kucharz, E, 1984) |
| "The excretion of the two hydroxylysine glycosides hydroxylysine-galactose-glucose and hydroxylysine-galactose was studied in the urine of normal healthy and experimental rats chronically treated with collagen-like syndrome inductors, hydralazine or binazine." | 7.67 | Urinary excretions of hydroxylysylglycosides in rats with experimentally induced collagen-like syndrome. ( Drozdz, M; Jendryczko, A; Magner, K, 1985) |
| " The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension." | 7.67 | Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report. ( Bar-Khayim, Y; Dgani, R; Lancet, M; Mogilner, BM; Nissim, F; Shoham, Z; Yemini, M, 1989) |
| "A reversible syndrome resembling systemic lupus erythematosus and induced by hydralazine hydrochloride therapy is a well-recognized phenomenon in adults but does not seem to have been reported in children." | 7.65 | Hydralazine-induced lupus erythematosus-like syndrome. ( Irias, JJ, 1975) |
| "Hydralazine-induced lupus was first described in 1953." | 5.48 | Hydralazine-associated antineutrophil cytoplasmic antibody vasculitis with pulmonary-renal syndrome. ( Aeddula, NR; Ansari, A; Juran, PJ; Pathireddy, S, 2018) |
| "This is the second case report of hydralazine induced Sweet's syndrome and lupus erythematosus." | 4.78 | Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature. ( Franz, T; Medsger, TA; Ramsey-Goldman, R; Solano, FX, 1990) |
| "The collagen-like syndrome was induced in rats by hydralazine application during 5 months." | 3.67 | Glucose tolerance in rats with hydralazine-induced collagen-like syndrome. ( Jendryczko, A; Kucharz, E, 1984) |
| "LE-positive collagen-like syndrome was produced in rats with chronic hydralazine treatment." | 3.67 | Blood histamine level in rats with hydralazine-induced collagen-like syndrome. Short communication. ( Jendryczko, A; Kucharz, E, 1984) |
| "The excretion of the two hydroxylysine glycosides hydroxylysine-galactose-glucose and hydroxylysine-galactose was studied in the urine of normal healthy and experimental rats chronically treated with collagen-like syndrome inductors, hydralazine or binazine." | 3.67 | Urinary excretions of hydroxylysylglycosides in rats with experimentally induced collagen-like syndrome. ( Drozdz, M; Jendryczko, A; Magner, K, 1985) |
| " The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension." | 3.67 | Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report. ( Bar-Khayim, Y; Dgani, R; Lancet, M; Mogilner, BM; Nissim, F; Shoham, Z; Yemini, M, 1989) |
| "An increase of soluble fractions of collagen and a decrease of insoluble ones was found in the skin of guinea pigs with collagen disease-like syndrome, produced by prolonged treatment with hydralazine." | 3.66 | Increased solubility of collagen. A biochemical defect in the experimental hydralizine-induced collagen disease-like syndrome. ( Drózdz, M; Kucharz, E, 1978) |
| "A reversible syndrome resembling systemic lupus erythematosus and induced by hydralazine hydrochloride therapy is a well-recognized phenomenon in adults but does not seem to have been reported in children." | 3.65 | Hydralazine-induced lupus erythematosus-like syndrome. ( Irias, JJ, 1975) |
| "A collagen-like syndrome was produced by a long-term administration of 1-hydrazinophthalazine (hydralazine) to guinea pigs." | 3.65 | Serum glycoproteins level and urinary glycosaminoglycans excretion in drug induced collagen-like syndrome in guinea pigs. ( Drózdz, M; Kucharz, E, 1976) |
| "Hydralazine-induced lupus was first described in 1953." | 1.48 | Hydralazine-associated antineutrophil cytoplasmic antibody vasculitis with pulmonary-renal syndrome. ( Aeddula, NR; Ansari, A; Juran, PJ; Pathireddy, S, 2018) |
| "Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases." | 1.27 | [Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. ( Wollina, U, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (88.89) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aeddula, NR | 1 |
| Pathireddy, S | 1 |
| Ansari, A | 1 |
| Juran, PJ | 1 |
| BEELAR, VP | 1 |
| KLEH, J | 1 |
| FAZEKAS, JF | 1 |
| RENZI, AA | 1 |
| GAUNT, R | 1 |
| PERRY, HM | 3 |
| SCHROEDER, HA | 1 |
| POSEY, EL | 1 |
| STEPHENSON, SL | 1 |
| SHACKMAN, NH | 1 |
| SWILLER, AI | 1 |
| MORRISON, M | 1 |
| STERNBERG, TH | 1 |
| BIERMAN, SM | 1 |
| HENN, MJ | 1 |
| PARKIN, TW | 1 |
| HARGRAVES, MM | 1 |
| ODEL, HM | 1 |
| Jendryczko, A | 3 |
| Kucharz, E | 5 |
| Wollina, U | 1 |
| Mansilla-Tinoco, R | 1 |
| Harland, SJ | 1 |
| Ryan, PJ | 1 |
| Bernstein, RM | 1 |
| Dollery, CT | 1 |
| Hughes, GR | 1 |
| Bulpitt, CJ | 1 |
| Morgan, A | 1 |
| Jones, JM | 1 |
| Macleod, WN | 1 |
| McWeeney, J | 1 |
| Finnegan, P | 1 |
| Drózdz, M | 4 |
| Wieczorek, M | 1 |
| Kotler, MN | 1 |
| Segal, BL | 1 |
| Miyasaka, N | 1 |
| Irias, JJ | 1 |
| Gallop, PM | 1 |
| Paz, MA | 1 |
| Kissin, MW | 1 |
| Williamson, RC | 1 |
| Juanola, X | 2 |
| Nolla, JM | 1 |
| Servitje, O | 2 |
| Valverde, J | 1 |
| Ramsey-Goldman, R | 1 |
| Franz, T | 1 |
| Solano, FX | 1 |
| Medsger, TA | 1 |
| Magner, K | 1 |
| Pettinger, WA | 1 |
| Mitchell, HC | 1 |
| Lee, HC | 1 |
| Redman, HC | 1 |
| Yemini, M | 1 |
| Shoham, Z | 1 |
| Dgani, R | 1 |
| Lancet, M | 1 |
| Mogilner, BM | 1 |
| Nissim, F | 1 |
| Bar-Khayim, Y | 1 |
| Schopf, RE | 1 |
| Hanauske-Abel, HM | 1 |
| Tschank, G | 1 |
| Schulte-Wissermann, H | 1 |
| Günzler, V | 1 |
| Sequeira, W | 1 |
| Polisky, RB | 1 |
| Alrenga, DP | 1 |
| Ribera, M | 1 |
| Rodriguez-Moreno, J | 1 |
| Doherty, M | 1 |
| Maddison, PJ | 1 |
| Grey, RH | 1 |
| Kincaid-Smith, P | 1 |
| Carey, RM | 1 |
| Coleman, M | 1 |
| Feder, A | 1 |
4 reviews available for hydralazine and Syndrome
| Article | Year |
|---|---|
Drug-induced lupus.
Topics: Antibodies, Antinuclear; Anticonvulsants; Ethosuximide; Female; Humans; Hydralazine; Lupus Erythemat | 1996 |
Posttranslational protein modifications, with special attention to collagen and elastin.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Ascorbic Acid; Collagen; Connective Tissue; Copp | 1975 |
Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature.
Topics: Acute Disease; Adult; Fever; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Neutrophils; | 1990 |
Late toxicity to hydralazine resembling systemic lupus erythematosus or rheumatoid arthritis.
Topics: Acetylation; Adult; Antibodies, Antinuclear; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Bloo | 1973 |
1 trial available for hydralazine and Syndrome
| Article | Year |
|---|---|
Pseudo renal artery stenosis (PRAS) syndrome.
Topics: Angiography; Blood Pressure; Body Weight; Creatinine; Double-Blind Method; Enalapril; Humans; Hydral | 1989 |
31 other studies available for hydralazine and Syndrome
| Article | Year |
|---|---|
Hydralazine-associated antineutrophil cytoplasmic antibody vasculitis with pulmonary-renal syndrome.
Topics: Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Biopsy; Blood Protein Electrophore | 2018 |
Rheumatoid arthritis-like syndrome during apresoline therapy: report of a case.
Topics: Arthritis; Arthritis, Rheumatoid; Hydralazine; Sympatholytics; Syndrome | 1953 |
The use of apresoline in the hypertensive arteriosclerotic syndrome.
Topics: Aged; Hydralazine; Hypertension; Sympatholytics; Syndrome | 1954 |
Apresoline (l-hydrazinophthalazine) in the experimental eclampsia-like syndrome and related aspects of water metabolism.
Topics: Eclampsia; Edema; Female; Hydralazine; Kidney; Pregnancy; Sympatholytics; Syndrome; Water | 1953 |
Syndrome simulating collagen disease caused by hydralazine (Apresoline).
Topics: Collagen; Collagen Diseases; Hydralazine; Hypertension; Sympatholytics; Syndrome | 1954 |
Syndrome resembling disseminated lupus occurring during apresoline therapy.
Topics: Hydralazine; Sympatholytics; Syndrome | 1954 |
Syndrome simulating acute disseminated lupus erythematosus: appearance after hydralazine (apresoline) therapy.
Topics: Diagnosis, Differential; Humans; Hydralazine; Lupus Erythematosus, Systemic; Sympatholytics; Syndrom | 1954 |
UNIQUE SYNDROMES INVOLVING THE SKIN INDUCED BY DRUGS, FOOD ADDITIVES, AND ENVIRONMENTAL CONTAMINANTS.
Topics: Aniline Compounds; Anti-Bacterial Agents; Dermatitis, Contact; Diagnosis, Differential; Drug Eruptio | 1963 |
Acute systemic lupus erythematosus syndrome from hydralazine hydrochloride.
Topics: Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Sympatholytics; Syndrome | 1955 |
Glucose tolerance in rats with hydralazine-induced collagen-like syndrome.
Topics: Animals; Blood Glucose; Collagen Diseases; Fasting; Glucose Tolerance Test; Hydralazine; Hyperglycem | 1984 |
Blood histamine level in rats with hydralazine-induced collagen-like syndrome. Short communication.
Topics: Animals; Collagen Diseases; Histamine; Hydralazine; Rats; Rats, Inbred Strains; Syndrome | 1984 |
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus | 1984 |
Hydralazine, antinuclear antibodies, and the lupus syndrome.
Topics: Acetylation; Antibodies, Antinuclear; Dose-Response Relationship, Drug; Female; Humans; Hydralazine; | 1982 |
Anaemia in the hydrallazine-induced Lupus syndrome.
Topics: Aged; Anemia; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Syndrome; Vasculitis | 1983 |
Vasodilator therapy of pulmonary hypertension in the CRST syndrome.
Topics: Calcinosis; Female; Humans; Hydralazine; Hypertension, Pulmonary; Male; Middle Aged; Raynaud Disease | 1982 |
Possible mechanisms of the hydralazine-related lupus-like syndrome.
Topics: Anemia, Hypochromic; Anticholesteremic Agents; Blood Pressure; Diastole; Dose-Response Relationship, | 1981 |
Histopathological changes in rabbits with long-term treatment with hydrazinophtalazines with or without hyperimmunization.
Topics: Animals; Collagen Diseases; Hydralazine; Immunization, Secondary; Kidney; Myocardium; Rabbits; Serum | 1981 |
The inflamed heart: pericarditis in the elderly.
Topics: Aged; Cardiac Tamponade; Daunorubicin; Echocardiography; Heart Neoplasms; Humans; Hydralazine; Myoca | 1980 |
Hydralazine-induced lupus erythematosus-like syndrome.
Topics: Acetylation; Acetyltransferases; Antibodies, Antinuclear; Arthritis, Rheumatoid; Child; DNA; Drug Hy | 1975 |
Hydrallazine-induced SLE-like syndrome presenting as a leg ulcer.
Topics: Humans; Hydralazine; Hypertension, Malignant; Leg Ulcer; Lupus Erythematosus, Systemic; Male; Middle | 1979 |
Increased solubility of collagen. A biochemical defect in the experimental hydralizine-induced collagen disease-like syndrome.
Topics: Animals; Chromatography; Collagen; Collagen Diseases; Hydralazine; Solubility; Swine; Syndrome | 1978 |
Serum glycoproteins level and urinary glycosaminoglycans excretion in drug induced collagen-like syndrome in guinea pigs.
Topics: Animals; Collagen Diseases; Disease Models, Animal; Glycoproteins; Glycosaminoglycans; Guinea Pigs; | 1976 |
Hydralazine induced lupus and Sweet's syndrome.
Topics: Aged; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Skin Diseases; Syndrome | 1991 |
Urinary excretions of hydroxylysylglycosides in rats with experimentally induced collagen-like syndrome.
Topics: Animals; Collagen; Collagen Diseases; Glycosides; Hydralazine; Hydroxylysine; Male; Neutrophils; Rat | 1985 |
Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report.
Topics: Adult; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Lupus Vulgaris; Pregnancy; Pregna | 1989 |
Effects of hydrazyl group containing drugs on leucocyte functions: an immunoregulatory model for the hydralazine-induced lupus-like syndrome.
Topics: Concanavalin A; Humans; Hydralazine; In Vitro Techniques; Isoniazid; Leukocytes; Luminescent Measure | 1985 |
Neutrophilic dermatosis (Sweet's syndrome). Association with a hydralazine-induced lupus syndrome.
Topics: Drug Eruptions; Female; Fever; Humans; Hydralazine; Leukocytosis; Lupus Erythematosus, Systemic; Mid | 1986 |
Acute neutrophilic dermatosis associated with hydralazine-induced lupus.
Topics: Aged; Humans; Hydralazine; Hypertension; Leukocytosis; Lupus Erythematosus, Cutaneous; Male; Neutrop | 1987 |
Hydralazine induced lupus syndrome with eye disease.
Topics: Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Middle Aged; Retinitis; Sy | 1985 |
Hydralazine--is there a safe dose?
Topics: Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Syndrome | 1985 |
Pericardial tamponade: a major presenting manifestation of hydralazine-induced lupus syndrome.
Topics: Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Hydralazine; Lupus Erythematosus, Sy | 1973 |