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hydralazine and Substance Withdrawal Syndrome

hydralazine has been researched along with Substance Withdrawal Syndrome in 4 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Research Excerpts

ExcerptRelevanceReference
"Sudden withdrawal of oral therapy with hydralazine for reduction of afterload in a patient precipitated severe congestive heart failure."7.66Precipitation of heart failure following sudden withdrawal of hydralazine. ( Black, JR; Mehta, J, 1979)
" It has also been used intravenously in phaeochromocytoma, tetanus, clonidine withdrawal, and as an adjunct to halothane to produce hypotensive anaesthesia."4.76Combined alpha- and beta-receptor inhibition in the treatment of hypertension. ( Prichard, BN, 1984)
" To test if these structural changes occur in the absence of raised blood pressure, hydralazine was administered to spontaneously hypertensive rats and normotensive controls prior to and during pregnancy (100 ml/l drinking water), and to the newborn males up to 21 weeks of age (16."3.67Prenatal and postnatal hydralazine treatment does not prevent renal vessel wall thickening in SHR despite the absence of hypertension. ( Forrest, JB; Lee, RM; Smeda, JS, 1988)
"Sudden withdrawal of oral therapy with hydralazine for reduction of afterload in a patient precipitated severe congestive heart failure."3.66Precipitation of heart failure following sudden withdrawal of hydralazine. ( Black, JR; Mehta, J, 1979)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prichard, BN1
Black, JR1
Mehta, J1
Penhall, RK1
Frewin, DB1
Smeda, JS1
Lee, RM1
Forrest, JB1

Reviews

1 review available for hydralazine and Substance Withdrawal Syndrome

ArticleYear
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
    Drugs, 1984, Volume: 28 Suppl 2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihyp

1984

Other Studies

3 other studies available for hydralazine and Substance Withdrawal Syndrome

ArticleYear
Precipitation of heart failure following sudden withdrawal of hydralazine.
    Chest, 1979, Volume: 75, Issue:6

    Topics: Administration, Oral; Aged; Aortic Valve Insufficiency; Digoxin; Furosemide; Heart Failure; Hemodyna

1979
Sinus tachycardis in a hypertensive patient: drug withdrawal phenomenon?
    The Medical journal of Australia, 1977, Nov-19, Volume: 2, Issue:21

    Topics: Arrhythmia, Sinus; Female; Humans; Hydralazine; Hypertension; Middle Aged; Propranolol; Substance Wi

1977
Prenatal and postnatal hydralazine treatment does not prevent renal vessel wall thickening in SHR despite the absence of hypertension.
    Circulation research, 1988, Volume: 63, Issue:3

    Topics: Animals; Animals, Newborn; Blood Pressure; Blood Vessels; Female; Hydralazine; Muscle, Smooth, Vascu

1988