Page last updated: 2024-10-28

hydralazine and Reperfusion Injury

hydralazine has been researched along with Reperfusion Injury in 5 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"Hydralazine has shown renoprotective effects in multiple kidney diseases and was shown to be a potent xanthine oxidase (XO) inhibitor."5.91Xanthine oxidase/NADPH oxidase inhibition by hydralazine attenuates acute kidney injury and prevents the transition of acute kidney injury to chronic kidney disease. ( Chang, TT; Chen, C; Chen, JW; Chiang, CH; Fang, SY; Lin, SC, 2023)
"Hydralazine has shown renoprotective effects in multiple kidney diseases and was shown to be a potent xanthine oxidase (XO) inhibitor."1.91Xanthine oxidase/NADPH oxidase inhibition by hydralazine attenuates acute kidney injury and prevents the transition of acute kidney injury to chronic kidney disease. ( Chang, TT; Chen, C; Chen, JW; Chiang, CH; Fang, SY; Lin, SC, 2023)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Leu, JG1
Su, WH1
Chen, YC1
Liang, YJ1
Chiang, CH1
Chen, C1
Fang, SY1
Lin, SC1
Chen, JW1
Chang, TT1
Li, Y1
Hou, D1
Chen, X1
Zhu, J1
Zhang, R1
Sun, W1
Li, P1
Tian, Y1
Kong, X1
Tampe, B1
Steinle, U1
Tampe, D1
Carstens, JL1
Korsten, P1
Zeisberg, EM1
Müller, GA1
Kalluri, R1
Zeisberg, M1
Bhabra, MS1
Hopkinson, DN1
Shaw, TE1
Hooper, TL1

Other Studies

5 other studies available for hydralazine and Reperfusion Injury

ArticleYear
Hydralazine attenuates renal inflammation in diabetic rats with ischemia/reperfusion acute kidney injury.
    European journal of pharmacology, 2021, Nov-05, Volume: 910

    Topics: Acute Kidney Injury; Animals; Cells, Cultured; Coculture Techniques; Diabetes Mellitus, Experimental

2021
Xanthine oxidase/NADPH oxidase inhibition by hydralazine attenuates acute kidney injury and prevents the transition of acute kidney injury to chronic kidney disease.
    Life sciences, 2023, Aug-15, Volume: 327

    Topics: Acute Kidney Injury; Animals; Enzyme Inhibitors; Fibrosis; Humans; Hydralazine; Inflammation; Kidney

2023
Hydralazine protects against renal ischemia-reperfusion injury in rats.
    European journal of pharmacology, 2019, Jan-15, Volume: 843

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cytokines; Hydralazine; Kidney; Male;

2019
Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression.
    Kidney international, 2017, Volume: 91, Issue:1

    Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; CpG Islands; Dioxygenases; D

2017
Attenuation of lung graft reperfusion injury by a nitric oxide donor.
    The Journal of thoracic and cardiovascular surgery, 1997, Volume: 113, Issue:2

    Topics: Animals; Cardioplegic Solutions; Disease Models, Animal; Disease Progression; Hemodynamics; Hydralaz

1997