Page last updated: 2024-10-28

hydralazine and Pulmonary Hypertension

hydralazine has been researched along with Pulmonary Hypertension in 83 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Research Excerpts

ExcerptRelevanceReference
"A two-year-old child dying of pulmonary hypertension and cor pulmonale secondary to bronchopulmonary dysplasia, was demonstrated to have reactive pulmonary hypertension in response to 100% oxygen and isoproterenol infusion."9.06Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia. ( Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ, 1988)
"The acute hemodynamic effects of both sublingual nifedipine (N) and intravenous hydralazine (Hy) were studied in 5 patients with primary pulmonary hypertension to ascertain whether the capacity for pulmonary vasodilatation was generalized or drug-specific, and to determine which of the 2 agents had preferential pulmonary vasodilatory effects."7.67Hemodynamic effects of nifedipine versus hydralazine in primary pulmonary hypertension. ( Borer, JS; Fisher, J; Goldberg, HL; Mermelstein, M; Moses, JW; Niarchos, AP; Whitman, HH, 1984)
"Reports on hemodynamic effects of hydralazine on pulmonary hypertension (primary or secondary) usually include cases with severe disease or with mixed varieties of pulmonary vascular disease."7.67Effects of hydralazine on hemodynamics, ventilation, and gas exchange in patients with chronic obstructive pulmonary disease and pulmonary hypertension. ( Chun, DS; Dolan, GF; Keller, CA; Minh, VD; Shepard, JW; Vasquez, P, 1984)
"Administration of hydralazine in patients with pulmonary hypertension has been reported to cause excessive systemic vasodilatation, limiting its clinical utility (N Engl J Med 1982; 306: 1326)."7.67Continuous, low dose of hydralazine, reduces acute hypoxic pulmonary hypertension without a corresponding fall in systemic arterial pressure. ( Kobayashi, T; Yoshimura, K, 1986)
"Hydralazine has been shown to increase minute ventilation, alveolar ventilation, and arterial partial pressure of oxygen (PaO2) after short-term administration in patients with chronic obstructive pulmonary disease and pulmonary hypertension."7.67Long-term effects of hydralazine on ventilation and blood gas values in patients with chronic obstructive pulmonary disease and pulmonary hypertension. ( Corriveau, ML; Dolan, GF, 1987)
"Hydralazine has been shown to increase minute ventilation (VE) in patients with chronic obstructive pulmonary disease and pulmonary hypertension."7.67Effects of hydralazine on mouth occlusion pressure and ventilatory response to hypercapnia in patients with chronic obstructive pulmonary disease and pulmonary hypertension. ( Corriveau, ML; Dolan, GF; Shepard, JW, 1987)
"Hydralazine was administered short-term to 13 patients who had stable interstitial lung disease (ILD), pulmonary arterial hypertension (PAH); mean pulmonary arterial pressure ( [PAP]=26 +/- 9 mm Hg), and cor pulmonale (CP)."7.67Hemodynamic effect of hydralazine in interstitial lung disease patients with cor pulmonale. Immediate and short-term evaluation at rest and during exercise. ( Barrios, R; Gomez, A; Lupi-Herrera, E; Martinez, W; Sandoval, J; Seoane, M; Verdejo, J, 1985)
"A patient who developed pulmonary hypertension and systemic lupus erythematosus as a complication of hydralazine therapy is reported."7.67Pulmonary hypertension in hydralazine induced systemic lupus erythematosus: association with C4 null allele. ( Asherson, RA; Benbow, AG; Hughes, GR; Jackson, N; Speirs, CJ, 1986)
"30 mg/kg) doses of intravenous hydralazine was evaluated in 26 consecutive patients with severe pulmonary hypertension due to cor pulmonale (nine patients), primary pulmonary hypertension (11 patients), or pulmonary embolism (six patients)."7.66Haemodynamic response to intravenous hydralazine in patients with pulmonary hypertension. ( Choo, MH; McGoon, MD; Moyer, TP; Reeder, GS; Seward, JB; Vlietstra, RE, 1983)
"Thirteen consecutive patients with primary and secondary pulmonary hypertension who had normal left ventricular function were treated with hydralazine in an effort to reduce pulmonary vascular resistance and clinical symptoms."7.66Deleterious effects of hydralazine in patients with pulmonary hypertension. ( Dash, H; Greenberg, B; Massie, B; Packer, M, 1982)
"To evaluate the hemodynamic effects of hydralazine in four patients with primary pulmonary hypertension, we catheterized the right side of the heart before and 48 hours after starting therapy with oral hydralazine, 50 mg every six hours."7.66Oral hydralazine therapy for primary pulmonary hypertension. ( Peter, RH; Rubin, LJ, 1980)
"Progressive dyspnea and syncope occurred in a young woman with primary pulmonary hypertension despite therapy with hydralazine."7.66Hemodynamic effects of nifedipine in primary pulmonary hypertension. ( Douglas, JS, 1983)
"The effects of 3 types of vasoactive agents, hydralazine, nifedipine and amrinone, were evaluated in 7 patients with primary pulmonary hypertension (PPH)."7.66Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension. ( Ganz, R; Levy, PS; Rich, S, 1983)
"Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13."7.65Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. ( Bennet, CM; Blaufuss, A; Wilburn, RL, 1975)
"Urapidil is a new vasodilator that acts by postsynaptic alpha 1-blockade while inhibiting the aortic pressure baroreceptor reflex and reducing central sympathetic tone."6.66Hemodynamic effects of urapidil in patients with pulmonary hypertension. A comparative study with hydralazine. ( Abrouk, F; Adnot, S; Brun-Buisson, C; Defouilloy, C; Lemaire, F; Piquet, J, 1987)
"Pulmonary hypertension was produced in sheep by the continuous administration of the thromboxane A2-mimetic U46619."5.28Effects of prostaglandin E1 and hydralazine on the longitudinal distribution of pulmonary vascular resistance during vasoconstrictor pulmonary hypertension in sheep. ( Pearl, RG; Siegel, LC, 1992)
"Hydralazine has been employed as a test drug, but because of its long duration of action there is a risk of sustained systemic arterial hypotension in patients with a fixed pulmonary vascular resistance."5.27A comparison of the acute hemodynamic effects of prostacyclin and hydralazine in primary pulmonary hypertension. ( Cato, AE; Frosolono, MF; Groves, BM; Reeves, JT; Rubin, LJ, 1985)
"A two-year-old child dying of pulmonary hypertension and cor pulmonale secondary to bronchopulmonary dysplasia, was demonstrated to have reactive pulmonary hypertension in response to 100% oxygen and isoproterenol infusion."5.06Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia. ( Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ, 1988)
"The acute hemodynamic effects of both sublingual nifedipine (N) and intravenous hydralazine (Hy) were studied in 5 patients with primary pulmonary hypertension to ascertain whether the capacity for pulmonary vasodilatation was generalized or drug-specific, and to determine which of the 2 agents had preferential pulmonary vasodilatory effects."3.67Hemodynamic effects of nifedipine versus hydralazine in primary pulmonary hypertension. ( Borer, JS; Fisher, J; Goldberg, HL; Mermelstein, M; Moses, JW; Niarchos, AP; Whitman, HH, 1984)
"Reports on hemodynamic effects of hydralazine on pulmonary hypertension (primary or secondary) usually include cases with severe disease or with mixed varieties of pulmonary vascular disease."3.67Effects of hydralazine on hemodynamics, ventilation, and gas exchange in patients with chronic obstructive pulmonary disease and pulmonary hypertension. ( Chun, DS; Dolan, GF; Keller, CA; Minh, VD; Shepard, JW; Vasquez, P, 1984)
"The hemodynamic and clinical responses to calcium channel blockade with verapamil and nifedipine were compared with those of hydralazine in 12 patients with pulmonary hypertension secondary to obliterative pulmonary vascular disease."3.67Adverse hemodynamic and clinical effects of calcium channel blockade in pulmonary hypertension secondary to obliterative pulmonary vascular disease. ( Medina, N; Packer, M; Yushak, M, 1984)
"Hydralazine has been shown to increase minute ventilation, alveolar ventilation, and arterial partial pressure of oxygen (PaO2) after short-term administration in patients with chronic obstructive pulmonary disease and pulmonary hypertension."3.67Long-term effects of hydralazine on ventilation and blood gas values in patients with chronic obstructive pulmonary disease and pulmonary hypertension. ( Corriveau, ML; Dolan, GF, 1987)
" Because Indo may interfere with the hypotensive effect of hydralazine and because hydralazine has been proposed in the treatment of patients with pulmonary hypertension, 7 of these patients also received 0."3.67Effects of indomethacin on pulmonary hemodynamics and gas exchange in patients with pulmonary artery hypertension, interference with hydralazine. ( Adnot, S; Brun-Buisson, C; de Cremoux, H; Defouilloy, C; Lemaire, F; Piquet, J, 1987)
"Hydralazine has been shown to increase minute ventilation (VE) in patients with chronic obstructive pulmonary disease and pulmonary hypertension."3.67Effects of hydralazine on mouth occlusion pressure and ventilatory response to hypercapnia in patients with chronic obstructive pulmonary disease and pulmonary hypertension. ( Corriveau, ML; Dolan, GF; Shepard, JW, 1987)
"Administration of hydralazine in patients with pulmonary hypertension has been reported to cause excessive systemic vasodilatation, limiting its clinical utility (N Engl J Med 1982; 306: 1326)."3.67Continuous, low dose of hydralazine, reduces acute hypoxic pulmonary hypertension without a corresponding fall in systemic arterial pressure. ( Kobayashi, T; Yoshimura, K, 1986)
"Hydralazine was administered short-term to 13 patients who had stable interstitial lung disease (ILD), pulmonary arterial hypertension (PAH); mean pulmonary arterial pressure ( [PAP]=26 +/- 9 mm Hg), and cor pulmonale (CP)."3.67Hemodynamic effect of hydralazine in interstitial lung disease patients with cor pulmonale. Immediate and short-term evaluation at rest and during exercise. ( Barrios, R; Gomez, A; Lupi-Herrera, E; Martinez, W; Sandoval, J; Seoane, M; Verdejo, J, 1985)
"A patient who developed pulmonary hypertension and systemic lupus erythematosus as a complication of hydralazine therapy is reported."3.67Pulmonary hypertension in hydralazine induced systemic lupus erythematosus: association with C4 null allele. ( Asherson, RA; Benbow, AG; Hughes, GR; Jackson, N; Speirs, CJ, 1986)
"30 mg/kg) doses of intravenous hydralazine was evaluated in 26 consecutive patients with severe pulmonary hypertension due to cor pulmonale (nine patients), primary pulmonary hypertension (11 patients), or pulmonary embolism (six patients)."3.66Haemodynamic response to intravenous hydralazine in patients with pulmonary hypertension. ( Choo, MH; McGoon, MD; Moyer, TP; Reeder, GS; Seward, JB; Vlietstra, RE, 1983)
"Progressive dyspnea and syncope occurred in a young woman with primary pulmonary hypertension despite therapy with hydralazine."3.66Hemodynamic effects of nifedipine in primary pulmonary hypertension. ( Douglas, JS, 1983)
"The effects of 3 types of vasoactive agents, hydralazine, nifedipine and amrinone, were evaluated in 7 patients with primary pulmonary hypertension (PPH)."3.66Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension. ( Ganz, R; Levy, PS; Rich, S, 1983)
"Thirteen consecutive patients with primary and secondary pulmonary hypertension who had normal left ventricular function were treated with hydralazine in an effort to reduce pulmonary vascular resistance and clinical symptoms."3.66Deleterious effects of hydralazine in patients with pulmonary hypertension. ( Dash, H; Greenberg, B; Massie, B; Packer, M, 1982)
"Hydralazine reduces pulmonary vascular resistance in patients with primary and secondary pulmonary hypertension, but the effects on right ventricular function of a change in resistance without a reduction in pulmonary arterial pressure are not known."3.66The effects of oral hydralazine on right ventricular end-diastolic pressure in patients with right ventricular failure. ( Handel, F; Peter, RH; Rubin, LJ, 1982)
"To evaluate the hemodynamic effects of hydralazine in four patients with primary pulmonary hypertension, we catheterized the right side of the heart before and 48 hours after starting therapy with oral hydralazine, 50 mg every six hours."3.66Oral hydralazine therapy for primary pulmonary hypertension. ( Peter, RH; Rubin, LJ, 1980)
"Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13."3.65Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. ( Bennet, CM; Blaufuss, A; Wilburn, RL, 1975)
"Urapidil is a new vasodilator that acts by postsynaptic alpha 1-blockade while inhibiting the aortic pressure baroreceptor reflex and reducing central sympathetic tone."2.66Hemodynamic effects of urapidil in patients with pulmonary hypertension. A comparative study with hydralazine. ( Abrouk, F; Adnot, S; Brun-Buisson, C; Defouilloy, C; Lemaire, F; Piquet, J, 1987)
"Hydralazine was the only drug that significantly increased cardiac output (1."1.28Vasodilator therapy in microembolic porcine pulmonary hypertension. ( McLean, RF; Pearl, RG; Prielipp, RC; Rosenthal, MH, 1990)
"Thus, in this canine model of acute pulmonary embolism: 1) VA/Q distributions were moderately impaired accounting for only slight hypoxemia, and 2) pulmonary hypertension was partially reversible by hydralazine and by nitroprusside without associated non-flow-dependent change in VA/Q distributions and arterial oxygenation."1.28Effects of vasodilators on gas exchange in acute canine embolic pulmonary hypertension. ( Delcroix, M; Leeman, M; Lejeune, P; Mélot, C; Naeije, R, 1990)
"Pulmonary hypertension was produced in sheep by the continuous administration of the thromboxane A2-mimetic U46619."1.28Effects of prostaglandin E1 and hydralazine on the longitudinal distribution of pulmonary vascular resistance during vasoconstrictor pulmonary hypertension in sheep. ( Pearl, RG; Siegel, LC, 1992)
"Hydralazine was administered in a dose sufficient to double CO."1.27Pulmonary vascular effects of hydralazine in a canine preparation of pulmonary thromboembolism. ( Ducas, J; Girling, L; Prewitt, RM; Schick, U, 1986)
"A 23-year-old woman with systemic lupus erythematosus was found to have severe pulmonary hypertension with secondary patency of the foramen ovale."1.27Danger of vasodilator therapy for pulmonary hypertension in patent foramen ovale. ( Girard, P; Laine, JF; Motté, G; Petitpretz, P; Slama, M, 1986)
"Hydralazine has been employed as a test drug, but because of its long duration of action there is a risk of sustained systemic arterial hypotension in patients with a fixed pulmonary vascular resistance."1.27A comparison of the acute hemodynamic effects of prostacyclin and hydralazine in primary pulmonary hypertension. ( Cato, AE; Frosolono, MF; Groves, BM; Reeves, JT; Rubin, LJ, 1985)
"Hydralazine was administered acutely to 12 patients who had pulmonary arterial hypertension of unknown cause."1.26The role of hydralazine therapy for pulmonary arterial hypertension of unknown cause. ( Bialostozky, D; Lupi-Herrera, E; Sandoval, J; Seoane, M, 1982)
"Isosorbide dinitrate was the only drug that elicited any reduction in pulmonary artery pressure; pulmonary vascular resistance decreased modestly."1.26Vasodilators and prostaglandin inhibitors in primary pulmonary hypertension. ( Bambach, D; Fontana, ME; Hermiller, JB; Huss, P; Leier, CV; Magorien, RD; Thompson, MJ; Unverferth, DV, 1982)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199070 (84.34)18.7374
1990's12 (14.46)18.2507
2000's0 (0.00)29.6817
2010's1 (1.20)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wong, CM1
Preston, IR1
Hill, NS1
Suzuki, YJ1
Tuxen, DV1
Powles, AC1
Mathur, PN1
Pugsley, SO1
Campbell, EJ1
Rubin, LJ8
Dubiel, JP1
Pyzik, Z1
Brzostek, T1
Kolasińska-Kloch, W1
Peter, RH4
Rubin, L1
Brent, BN2
Berger, HJ2
Matthay, RA2
Mahler, D1
Pytlik, L1
Zaret, BL2
Fisher, J1
Borer, JS1
Moses, JW1
Goldberg, HL1
Niarchos, AP1
Whitman, HH1
Mermelstein, M1
Keller, CA2
Shepard, JW2
Chun, DS2
Dolan, GF4
Vasquez, P1
Minh, VD1
Packer, M2
Medina, N1
Yushak, M1
Cordasco, EM1
Rich, S5
Ganz, R1
Levy, PS4
McGoon, MD1
Seward, JB1
Vlietstra, RE1
Choo, MH1
Moyer, TP1
Reeder, GS1
Rüegger, M1
Medici, TC1
Cotter, L1
Mahler, DA1
Lister, G1
Stanbrook, HS1
Morris, KG1
McMurtry, IF1
Pannarale, G2
Gaspardone, A2
Acconcia, MC2
Valente, A2
Martinez, J1
Lam, W1
Rosen, KM1
Douglas, JS1
Lupi-Herrera, E2
Sandoval, J3
Seoane, M2
Bialostozky, D1
Fishman, AP2
Greenberg, B1
Massie, B1
Dash, H1
Kadowitz, PJ1
Hyman, AL1
Handel, F1
Kronzon, I1
Cohen, M1
Winer, HE1
Moser, KM1
McWeeney, J1
Finnegan, P1
Hermiller, JB1
Bambach, D1
Thompson, MJ1
Huss, P1
Fontana, ME1
Magorien, RD1
Unverferth, DV1
Leier, CV1
Farber, H1
Glauser, FL1
Fripp, RR1
Gewitz, MH1
Werner, JC1
Whitman, V1
Rashkind, WJ1
Das, UN1
Reeves, JT2
Santini, D1
Fox, D1
Kloner, RA1
Konstam, M1
Rude, RE1
Lorell, BH1
Elkayam, U1
Volkova, LI1
Shteĭngart, IuN1
Gavaghan, BJ1
Lapointe, JM1
Thomas, WP1
Collados, MT1
López, S1
Massó, FA1
Páez, A1
Borbolla, JR1
Montaño, LF1
Fleischmann, LE1
Wilburn, RL1
Blaufuss, A1
Bennet, CM1
Friedman, DM1
Mitnick, HJ1
Danilowicz, D1
Priebe, HJ2
Vorob'ev, LP1
Maev, IV1
Pearl, RG3
Siegel, LC1
Lewczuk, J1
Wrabec, K1
Martin, GR1
Chauvin, L1
Short, BL1
Phlippoteau, C1
Brenot, F1
Blétry, O1
Simmonneau, G1
Duroux, P1
McLean, RF1
Prielipp, RC2
Rosenthal, MH2
Delcroix, M1
Mélot, C1
Lejeune, P1
Leeman, M1
Naeije, R1
Mazza, F1
Morra, AM1
Morra, MG1
Catalano, M1
Contiello, V1
Polcino, A1
Palevsky, HI1
Hughes, JD1
Hammond, TG1
Mosesson, MW1
Sun, BT1
Corriveau, ML3
Rosen, BJ1
Goodman, G1
Perkin, RM1
Anas, NG1
Sperling, DR1
Hicks, DA1
Rowen, M1
Kasian, GF1
Ninan, A1
Duncan, WJ1
Bingham, WT1
Mersal, A1
Tyrrell, MJ1
Sankaran, K1
Adnot, S3
Defouilloy, C3
Abrouk, F2
Kouzan, S1
Lemaire, F3
Halpern, SM1
Shah, PK1
Lehrman, S1
Goldberg, HS1
Jasper, AC1
Koerner, SK1
Brun-Buisson, C2
Piquet, J2
de Cremoux, H1
Ducas, J1
Girling, L1
Schick, U1
Prewitt, RM1
Laine, JF1
Slama, M1
Petitpretz, P1
Girard, P1
Motté, G1
Cernohorský, D1
Král, B1
Hamet, A1
Eliás, J1
Tilser, P1
Rozánek, P1
Sramar, V1
Koudelka, V1
Asherson, RA1
Benbow, AG1
Speirs, CJ1
Jackson, N1
Hughes, GR1
Yoshimura, K1
Kobayashi, T1
Groves, BM1
Frosolono, MF1
Cato, AE1
Dal Nogare, AR1
D'Alonzo, GE1
Dantzker, DR1
Cerdá, E1
Esteban, A1
de la Cal, MA1
Fernández, A1
García, A1
Verdejo, J1
Gomez, A1
Barrios, R1
Martinez, W1
Brundage, BH1
Gladman, DD1
Sternberg, L1
Ohar, J1
Polatty, C1
Robichaud, A1
Fowler, A1
Vetrovec, G1
Glauser, F1

Reviews

6 reviews available for hydralazine and Pulmonary Hypertension

ArticleYear
Cardiovascular effects of vasodilator therapy for pulmonary arterial hypertension.
    Clinics in chest medicine, 1983, Volume: 4, Issue:2

    Topics: Cardiac Output; Echocardiography; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Hypote

1983
The pharmacologic control of the pulmonary circulation in pulmonary hypertension.
    Advances in internal medicine, 1984, Volume: 29

    Topics: Acetylcholine; Adult; Aminophylline; Calcium Channel Blockers; Diazoxide; Female; Humans; Hydralazin

1984
[Early pulmonary hypertension: current therapeutic prospectives].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:9

    Topics: Calcium Channel Blockers; Captopril; Diazoxide; Diltiazem; Humans; Hydralazine; Hypertension, Pulmon

1982
[Value of vasodilator agents in the treatment of diseases with pulmonary hypertension caused by chronic obstructive lung diseases].
    Pneumonologia i alergologia polska, 1991, Volume: 59, Issue:3-4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B

1991
Vasodilator therapy for primary pulmonary hypertension.
    Annual review of medicine, 1985, Volume: 36

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Calcium Channel Blockers; Hum

1985
Primary pulmonary hypertension. An analysis of 28 cases and a review of the literature.
    Medicine, 1986, Volume: 65, Issue:1

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aminorex; Anticoagulants; Autoimmune Diseases; Calc

1986

Trials

5 trials available for hydralazine and Pulmonary Hypertension

ArticleYear
[Treatment of primary pulmonary hypertension with hydralazine].
    Polskie Archiwum Medycyny Wewnetrznej, 1983, Volume: 69, Issue:6

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hydralazine; Hypertension, Pulmonar

1983
Characterization of von Willebrand factor in primary pulmonary hypertension.
    Heart and vessels, 1999, Volume: 14, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Antigens; Biomarkers; Blotting, Western; Calcium Channel Blockers;

1999
[Effects of corinfar, nitrosorbide and apressin on external respiration and blood flow in chronic obstructive bronchitis].
    Rossiiskii meditsinskii zhurnal : organ Ministerstva zdravookhraneniia RSFSR, 1992, Issue:1

    Topics: Blood Circulation; Bronchitis; Humans; Hydralazine; Hypertension, Pulmonary; Isosorbide Dinitrate; N

1992
Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia.
    The Canadian journal of cardiology, 1988, Volume: 4, Issue:4

    Topics: Albuterol; Bronchopulmonary Dysplasia; Child, Preschool; Diltiazem; Humans; Hydralazine; Hypertensio

1988
Hemodynamic effects of urapidil in patients with pulmonary hypertension. A comparative study with hydralazine.
    The American review of respiratory disease, 1987, Volume: 135, Issue:2

    Topics: Aged; Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmo

1987

Other Studies

72 other studies available for hydralazine and Pulmonary Hypertension

ArticleYear
Iron chelation inhibits the development of pulmonary vascular remodeling.
    Free radical biology & medicine, 2012, Nov-01, Volume: 53, Issue:9

    Topics: Animals; Blood Proteins; Case-Control Studies; Cell Proliferation; Cells, Cultured; Deferoxamine; Fe

2012
Detrimental effects of hydralazine in patients with chronic air-flow obstruction and pulmonary hypertension. A combined hemodynamic and radionuclide study.
    The American review of respiratory disease, 1984, Volume: 129, Issue:3

    Topics: Aged; Angiography; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases

1984
Contrasting acute effects of vasodilators (nitroglycerin, nitroprusside, and hydralazine) on right ventricular performance in patients with chronic obstructive pulmonary disease and pulmonary hypertension: a combined radionuclide-hemodynamic study.
    The American journal of cardiology, 1983, Volume: 51, Issue:10

    Topics: Adult; Aged; Female; Heart; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Lung Disease

1983
Hemodynamic effects of nifedipine versus hydralazine in primary pulmonary hypertension.
    The American journal of cardiology, 1984, Sep-01, Volume: 54, Issue:6

    Topics: Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmona

1984
Effects of hydralazine on hemodynamics, ventilation, and gas exchange in patients with chronic obstructive pulmonary disease and pulmonary hypertension.
    The American review of respiratory disease, 1984, Volume: 130, Issue:4

    Topics: Drug Tolerance; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases, Obstructi

1984
Adverse hemodynamic and clinical effects of calcium channel blockade in pulmonary hypertension secondary to obliterative pulmonary vascular disease.
    Journal of the American College of Cardiology, 1984, Volume: 4, Issue:5

    Topics: Adult; Calcium Channel Blockers; Cardiac Output; Exercise Test; Female; Hemodynamics; Humans; Hydral

1984
Pulmonary vascular disease--overview.
    Angiology, 1983, Volume: 34, Issue:10

    Topics: Angiography; Heparin; Humans; Hydralazine; Hypertension, Pulmonary; Lung; Lung Diseases, Obstructive

1983
Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension.
    The American journal of cardiology, 1983, Nov-01, Volume: 52, Issue:8

    Topics: Adult; Aminopyridines; Amrinone; Cardiac Catheterization; Cardiac Output; Female; Humans; Hydralazin

1983
Haemodynamic response to intravenous hydralazine in patients with pulmonary hypertension.
    British heart journal, 1983, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Pressure; Female; Follow-Up Studies; Hemodynamics; Humans; Hydralazin

1983
[New therapies for cor pulmonale?].
    Deutsche medizinische Wochenschrift (1946), 1983, Dec-09, Volume: 108, Issue:49

    Topics: Bloodletting; Humans; Hydralazine; Hypertension, Pulmonary; Hypoxia; Iron; Lung Diseases, Obstructiv

1983
Vasodilator treatment of primary pulmonary hypertension.
    Advances in experimental medicine and biology, 1984, Volume: 164

    Topics: Administration, Oral; Adult; Diazoxide; Female; Humans; Hydralazine; Hypertension, Pulmonary; Middle

1984
Relationship between oxygen uptake and oxygen transport in stable patients with chronic obstructive pulmonary disease. Physiologic effects of nitroprusside and hydralazine.
    The American review of respiratory disease, 1984, Volume: 129, Issue:5

    Topics: Aged; Biological Transport; Ferricyanides; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonar

1984
Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists.
    The American review of respiratory disease, 1984, Volume: 130, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Hydralazine; Hypertension, Pulmonary; Hypoxia; Male; Nifedipine; Pulmon

1984
Reassessment of the effects of vasodilator drugs in primary pulmonary hypertension: guidelines for determining a pulmonary vasodilator response.
    American heart journal, 1983, Volume: 105, Issue:1

    Topics: Adult; Blood Pressure; Cardiac Catheterization; Cardiac Output; Diazoxide; Female; Humans; Hydralazi

1983
Hemodynamic effects of nifedipine in primary pulmonary hypertension.
    Journal of the American College of Cardiology, 1983, Volume: 2, Issue:1

    Topics: Adult; Exercise Test; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Nifedipine

1983
[Primary pulmonary hypertension: current therapeutic prospectives].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:9

    Topics: Calcium Channel Blockers; Diazoxide; Heart Rate; Humans; Hydralazine; Hypertension, Pulmonary; Isopr

1982
The role of hydralazine therapy for pulmonary arterial hypertension of unknown cause.
    Circulation, 1982, Volume: 65, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Child; Female; Follow-Up Studies; Hemodynamics; Humans; Hyd

1982
Unexplained pulmonary hypertension.
    Circulation, 1982, Volume: 65, Issue:4

    Topics: Humans; Hydralazine; Hypertension, Pulmonary; Pulmonary Circulation

1982
Deleterious effects of hydralazine in patients with pulmonary hypertension.
    The New England journal of medicine, 1982, Jun-03, Volume: 306, Issue:22

    Topics: Adult; Aged; Blood Pressure; Drug Evaluation; Female; Heart Rate; Humans; Hydralazine; Hypertension,

1982
Hydralazine and the treatment of primary pulmonary hypertension.
    The New England journal of medicine, 1982, Jun-03, Volume: 306, Issue:22

    Topics: Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary

1982
The effects of oral hydralazine on right ventricular end-diastolic pressure in patients with right ventricular failure.
    Circulation, 1982, Volume: 65, Issue:7

    Topics: Adult; Aged; Arterioles; Blood Pressure; Cardiac Output; Female; Heart Failure; Humans; Hydralazine;

1982
Adverse effect of hydralazine in patients with primary pulmonary hypertension.
    JAMA, 1982, Jun-11, Volume: 247, Issue:22

    Topics: Administration, Oral; Adult; Blood Pressure; Cardiac Output; Female; Humans; Hydralazine; Hypertensi

1982
Idiopathic pulmonary hypertension: therapeutic opportunities and pitfalls.
    JAMA, 1982, Jun-11, Volume: 247, Issue:22

    Topics: Diagnosis, Differential; Humans; Hydralazine; Hypertension, Pulmonary; Risk; Vascular Resistance

1982
Vasodilator therapy of pulmonary hypertension in the CRST syndrome.
    Irish journal of medical science, 1982, Volume: 151, Issue:5

    Topics: Calcinosis; Female; Humans; Hydralazine; Hypertension, Pulmonary; Male; Middle Aged; Raynaud Disease

1982
Hydralazine in pulmonary hypertension.
    The New England journal of medicine, 1982, Nov-04, Volume: 307, Issue:19

    Topics: Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases, Obstructive; Nifedipine

1982
Vasodilators and prostaglandin inhibitors in primary pulmonary hypertension.
    Annals of internal medicine, 1982, Volume: 97, Issue:4

    Topics: Adolescent; Adult; Aspirin; Diazoxide; Dipyridamole; Female; Hemodynamics; Humans; Hydralazine; Hype

1982
The effect of oral hydralazine on the pulmonary hemodynamics of patients with pulmonary foreign body granulomatosis.
    Chest, 1982, Volume: 82, Issue:6

    Topics: Administration, Oral; Adult; Dyspnea; Granuloma; Hemodynamics; Humans; Hydralazine; Hypertension, Pu

1982
Oral hydralazine in patients with pulmonary vascular disease secondary to congenital heart disease.
    The American journal of cardiology, 1981, Volume: 48, Issue:2

    Topics: Administration, Oral; Cardiac Output; Child; Child, Preschool; Female; Heart Defects, Congenital; He

1981
Prostaglandins and pulmonary hypertension-further evidence.
    Medical hypotheses, 1981, Volume: 7, Issue:5

    Topics: Humans; Hydralazine; Hypertension, Pulmonary; Prostaglandins; Pulmonary Circulation; Regional Blood

1981
Hope in primary pulmonary hypertension.
    The New England journal of medicine, 1980, Jan-10, Volume: 302, Issue:2

    Topics: Child; Diazoxide; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Pregnancy; Tim

1980
Oral hydralazine therapy for primary pulmonary hypertension.
    The New England journal of medicine, 1980, Jan-10, Volume: 302, Issue:2

    Topics: Administration, Oral; Adult; Blood Pressure; Cardiac Catheterization; Cardiac Output; Female; Heart

1980
Vasodilator therapy for pulmonary hypertension.
    The New England journal of medicine, 1980, May-29, Volume: 302, Issue:22

    Topics: Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary

1980
Primary pulmonary hypertension: new approaches to therapy.
    American heart journal, 1980, Volume: 100, Issue:5

    Topics: Diazoxide; Female; Humans; Hydralazine; Hypertension, Pulmonary; Phentolamine; Pregnancy

1980
Pulmonary hypertension in systemic lupus erythematosus: hemodynamics and effects of vasodilator therapy.
    Clinical cardiology, 1980, Volume: 3, Issue:6

    Topics: Adult; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Lupus Erythematosus, Syst

1980
Vasodilator therapy in primary pulmonary hypertension.
    Chest, 1981, Volume: 79, Issue:3

    Topics: Adult; Diazoxide; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Isoproterenol;

1981
[Individual approach to vasodilator treatment of pulmonary hypertension in chronic bronchitis].
    Klinicheskaia meditsina, 1994, Volume: 72, Issue:6

    Topics: Adult; Aminophylline; Bronchitis; Chronic Disease; Humans; Hydralazine; Hypertension, Pulmonary; Mid

1994
Acute onset of pulmonary necrotising arteritis in a dog with a left-to-right patent ductus arteriosus.
    Australian veterinary journal, 1998, Volume: 76, Issue:12

    Topics: Acute Disease; Animals; Antihypertensive Agents; Dog Diseases; Dogs; Ductus Arteriosus, Patent; Echo

1998
Management of hypertensive crisis in children.
    Pediatric annals, 1977, Volume: 6, Issue:6

    Topics: Acute Disease; Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Diazoxide; Humans; Hy

1977
Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide.
    Circulation, 1975, Volume: 52, Issue:4

    Topics: Cardiac Catheterization; Drug Therapy, Combination; Echocardiography; Edema; Furosemide; Humans; Hyd

1975
Recovery from pulmonary hypertension in an adolescent with mixed connective tissue disease.
    Annals of the rheumatic diseases, 1992, Volume: 51, Issue:8

    Topics: Child; Cyclophosphamide; Female; Humans; Hydralazine; Hypertension, Pulmonary; Mixed Connective Tiss

1992
Myocardial ischemia during vasodilator therapy in a canine model of pulmonary hypertension and coronary insufficiency.
    Anesthesiology, 1992, Volume: 76, Issue:5

    Topics: Alprostadil; Animals; Coronary Disease; Coronary Vessels; Dogs; Hemodynamics; Hydralazine; Hypertens

1992
Effects of prostaglandin E1 and hydralazine on the longitudinal distribution of pulmonary vascular resistance during vasoconstrictor pulmonary hypertension in sheep.
    Anesthesiology, 1992, Volume: 76, Issue:1

    Topics: Alprostadil; Animals; Hydralazine; Hypertension, Pulmonary; Lung; Male; Prostaglandin Endoperoxides,

1992
Effects of hydralazine on cardiac performance in infants receiving extracorporeal membrane oxygenation.
    The Journal of pediatrics, 1991, Volume: 118, Issue:6

    Topics: Blood Flow Velocity; Cardiac Output; Cerebrovascular Circulation; Extracorporeal Membrane Oxygenatio

1991
[Vasodilator agents in pulmonary artery hypertension of systemic scleroderma].
    Revue des maladies respiratoires, 1990, Volume: 7, Issue:3

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Epoprostenol; Female; Humans; Hydralazine; Hypertension

1990
Vasodilator therapy in microembolic porcine pulmonary hypertension.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:1

    Topics: Alprostadil; Animals; Ferricyanides; Hemodynamics; Hydralazine; Hypertension, Pulmonary; Infusions,

1990
Effects of vasodilators on gas exchange in acute canine embolic pulmonary hypertension.
    Anesthesiology, 1990, Volume: 72, Issue:1

    Topics: Acute Disease; Alprostadil; Animals; Dogs; Hydralazine; Hypertension, Pulmonary; Nitroprusside; Pulm

1990
[Primary pulmonary hypertension: physiopathology and critical evaluation of the therapy].
    La Clinica terapeutica, 1989, Feb-28, Volume: 128, Issue:4

    Topics: Blood Pressure; Captopril; Drug Evaluation; Epoprostenol; Humans; Hydralazine; Hypertension, Pulmona

1989
Fatal small-bowel necrosis and pulmonary hypertension in sickle cell disease.
    Archives of internal medicine, 1989, Volume: 149, Issue:2

    Topics: Adult; Anemia, Sickle Cell; Humans; Hydralazine; Hypertension, Pulmonary; Hypotension; Infarction; I

1989
[Effect of hydralazine on the pulmonary arterial hypertension in monocrotaline induced cor pulmonale in Macacus rhesus].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1987, Volume: 10, Issue:4

    Topics: Animals; Arterioles; Hydralazine; Hypertension, Pulmonary; Lung; Macaca mulatta; Monocrotaline; Pulm

1987
Vasodilator therapy in vasoconstrictor-induced pulmonary hypertension in sheep.
    Anesthesiology, 1988, Volume: 68, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Disease Mo

1988
Efficacy of vasodilator therapy in canine model of acute pulmonary hypertension.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Alprostadil; Animals; Coronary Circulation; Disease Models, Animal; Dogs; Female; Heart Ventricles;

1988
Effect of posture, hydralazine, and nifedipine on hemodynamics, ventilation, and gas exchange in patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1988, Volume: 138, Issue:6

    Topics: Carbon Dioxide; Carbon Monoxide; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Lung Di

1988
Pulmonary hypertension in infants with bronchopulmonary dysplasia.
    The Journal of pediatrics, 1988, Volume: 112, Issue:1

    Topics: Bronchopulmonary Dysplasia; Collateral Circulation; Female; Hemodynamics; Humans; Hydralazine; Hyper

1988
Haemodynamic effects of urapidil compared to hydralazine in pulmonary hypertension.
    European journal of respiratory diseases. Supplement, 1986, Volume: 146

    Topics: Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Male; Oxygen; Piperazines

1986
Prostaglandin E1 as a screening vasodilator in primary pulmonary hypertension.
    Chest, 1987, Volume: 92, Issue:4

    Topics: Adult; Aged; Alprostadil; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Male;

1987
Long-term effects of hydralazine on ventilation and blood gas values in patients with chronic obstructive pulmonary disease and pulmonary hypertension.
    The American journal of medicine, 1987, Volume: 83, Issue:5

    Topics: Blood Gas Analysis; Follow-Up Studies; Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases,

1987
Effects of indomethacin on pulmonary hemodynamics and gas exchange in patients with pulmonary artery hypertension, interference with hydralazine.
    The American review of respiratory disease, 1987, Volume: 136, Issue:6

    Topics: Aged; Cardiac Catheterization; Drug Evaluation; Drug Interactions; Female; Hemodynamics; Humans; Hyd

1987
Pulmonary vascular effects of hydralazine in a canine preparation of pulmonary thromboembolism.
    Circulation, 1986, Volume: 73, Issue:5

    Topics: Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Hemodynamics; Hydralazine; Hy

1986
Danger of vasodilator therapy for pulmonary hypertension in patent foramen ovale.
    Chest, 1986, Volume: 89, Issue:6

    Topics: Adult; Blood Pressure; Cardiomyopathies; Female; Heart Septum; Humans; Hydralazine; Hypertension, Pu

1986
[Effect of dihydralazine Spofa on precapillary pulmonary hypertension].
    Vnitrni lekarstvi, 1986, Volume: 32, Issue:9

    Topics: Adult; Dihydralazine; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Male; Midd

1986
Pulmonary hypertension in hydralazine induced systemic lupus erythematosus: association with C4 null allele.
    Annals of the rheumatic diseases, 1986, Volume: 45, Issue:9

    Topics: Alleles; Female; HLA Antigens; HLA-C Antigens; Humans; Hydralazine; Hypertension, Pulmonary; Lupus E

1986
Effects of hydralazine on mouth occlusion pressure and ventilatory response to hypercapnia in patients with chronic obstructive pulmonary disease and pulmonary hypertension.
    The American review of respiratory disease, 1987, Volume: 135, Issue:1

    Topics: Administration, Oral; Cardiac Catheterization; Drug Evaluation; Hemodynamics; Humans; Hydralazine; H

1987
Continuous, low dose of hydralazine, reduces acute hypoxic pulmonary hypertension without a corresponding fall in systemic arterial pressure.
    Japanese circulation journal, 1986, Volume: 50, Issue:10

    Topics: Animals; Blood Pressure; Female; Hydralazine; Hypertension, Pulmonary; Hypoxia; Male; Sheep

1986
Vasodilators and pulmonary hypertension: where do we go from here?
    The American review of respiratory disease, 1987, Volume: 135, Issue:2

    Topics: Blood Pressure; Humans; Hydralazine; Hypertension, Pulmonary; Piperazines; Pulmonary Circulation; Va

1987
A comparison of the acute hemodynamic effects of prostacyclin and hydralazine in primary pulmonary hypertension.
    American heart journal, 1985, Volume: 110, Issue:6

    Topics: Blood Pressure; Cardiac Output; Epoprostenol; Female; Heart Rate; Hemodynamics; Humans; Hydralazine;

1985
The effects of hydralazine on exercise capacity in pulmonary hypertension secondary to chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1986, Volume: 133, Issue:3

    Topics: Exercise Test; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases, Obstructiv

1986
Magnitude and implications of spontaneous hemodynamic variability in primary pulmonary hypertension.
    The American journal of cardiology, 1985, Jan-01, Volume: 55, Issue:1

    Topics: Adult; Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulm

1985
Hemodynamic effects of vasodilators on pulmonary hypertension in decompensated chronic obstructive pulmonary disease.
    Critical care medicine, 1985, Volume: 13, Issue:4

    Topics: Aged; Blood Pressure; Female; Ferricyanides; Heart Rate; Hemodynamics; Humans; Hydralazine; Hyperten

1985
Hemodynamic effect of hydralazine in interstitial lung disease patients with cor pulmonale. Immediate and short-term evaluation at rest and during exercise.
    Chest, 1985, Volume: 87, Issue:5

    Topics: Administration, Oral; Adult; Blood Gas Analysis; Drug Administration Schedule; Female; Hemodynamics;

1985
The effect of vasodilator therapy on the clinical outcome of patients with primary pulmonary hypertension.
    Circulation, 1985, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Child; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Male;

1985
Pulmonary hypertension in systemic lupus erythematosus.
    The Journal of rheumatology, 1985, Volume: 12, Issue:2

    Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension, Pulmona

1985
The role of vasodilators in patients with progressive systemic sclerosis. Interstitial lung disease and pulmonary hypertension.
    Chest, 1985, Volume: 88, Issue:4 Suppl

    Topics: Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases; Nifedipine; Pulmonary Fibrosis; Sarcoid

1985