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hydralazine and Pulmonary Embolism

hydralazine has been researched along with Pulmonary Embolism in 11 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.

Research Excerpts

ExcerptRelevanceReference
"We employed a canine model of pulmonary embolism, induced by injection of autologous radiolabelled blood clots, to investigate effects of hydralazine and an increase in cardiac output per se on recombinant tissue plasminogen activator-induced thrombolysis."7.68Effects of hydralazine and increased cardiac output on recombinant tissue plasminogen activator-induced thrombolysis in canine pulmonary embolism. ( Chan, SM; Downes, AM; Ducas, J; Gu, SA; Prewitt, RM, 1991)
"We employed a canine model of pulmonary embolism, induced by injection of autologous radiolabelled blood clots, to investigate effects of hydralazine and an increase in cardiac output per se on recombinant tissue plasminogen activator-induced thrombolysis."3.68Effects of hydralazine and increased cardiac output on recombinant tissue plasminogen activator-induced thrombolysis in canine pulmonary embolism. ( Chan, SM; Downes, AM; Ducas, J; Gu, SA; Prewitt, RM, 1991)
"Hydralazine was the only drug that significantly increased cardiac output (1."1.28Vasodilator therapy in microembolic porcine pulmonary hypertension. ( McLean, RF; Pearl, RG; Prielipp, RC; Rosenthal, MH, 1990)
"Thus, in this canine model of acute pulmonary embolism: 1) VA/Q distributions were moderately impaired accounting for only slight hypoxemia, and 2) pulmonary hypertension was partially reversible by hydralazine and by nitroprusside without associated non-flow-dependent change in VA/Q distributions and arterial oxygenation."1.28Effects of vasodilators on gas exchange in acute canine embolic pulmonary hypertension. ( Delcroix, M; Leeman, M; Lejeune, P; Mélot, C; Naeije, R, 1990)
"Hydralazine was administered in a dose sufficient to double CO."1.27Pulmonary vascular effects of hydralazine in a canine preparation of pulmonary thromboembolism. ( Ducas, J; Girling, L; Prewitt, RM; Schick, U, 1986)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's5 (45.45)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yee, J1
Cordasco, EM1
Lee, KY1
Molloy, DW1
Slykerman, L1
Prewitt, RM3
Bates, ER1
Crevey, BJ1
Sprague, FR1
Pitt, B1
Ueno, Y1
Kawashima, A1
Koike, H1
Nishio, S1
Lupi-Herrera, E1
Furuya, ME1
Sandoval, J1
Correa, E1
Leal, ME1
Quesada, A1
Palomar, A1
Barrios, R1
Downes, AM1
Gu, SA1
Chan, SM1
Ducas, J2
McLean, RF1
Prielipp, RC1
Rosenthal, MH1
Pearl, RG1
Delcroix, M1
Mélot, C1
Lejeune, P1
Leeman, M1
Naeije, R1
Priebe, HJ1
Girling, L1
Schick, U1

Other Studies

11 other studies available for hydralazine and Pulmonary Embolism

ArticleYear
PGX: Pharmacogenomics During Generation X.
    Advances in chronic kidney disease, 2016, Volume: 23, Issue:2

    Topics: Anticoagulants; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Heart Failure; H

2016
Pulmonary vascular disease--overview.
    Angiology, 1983, Volume: 34, Issue:10

    Topics: Angiography; Heparin; Humans; Hydralazine; Hypertension, Pulmonary; Lung; Lung Diseases, Obstructive

1983
Effects of hydralazine and nitroprusside on cardiopulmonary function when a decrease in cardiac output complicates a short-term increase in pulmonary vascular resistance.
    Circulation, 1983, Volume: 68, Issue:6

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Ferricyanides; Hydralazine; Nitroprusside; Pulmonary

1983
Oral hydralazine therapy for acute pulmonary embolism and low output state.
    Archives of internal medicine, 1981, Volume: 141, Issue:11

    Topics: Administration, Oral; Aged; Cardiac Output, Low; Female; Hemodynamics; Humans; Hydralazine; Pulmonar

1981
Effect of beraprost sodium, a stable prostacyclin analogue, on pulmonary thromboembolism in mice.
    Thrombosis research, 1995, Jan-15, Volume: 77, Issue:2

    Topics: Administration, Oral; Alprostadil; Animals; Aspirin; Bridged Bicyclo Compounds; Collagen; Diltiazem;

1995
Effect of hydralazine on vascular mechanics in a canine lobar preparation of pulmonary embolism.
    Lung, 1992, Volume: 170, Issue:5

    Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; Hemodynamics; Hydralazine; Pulmonary Embo

1992
Effects of hydralazine and increased cardiac output on recombinant tissue plasminogen activator-induced thrombolysis in canine pulmonary embolism.
    Chest, 1991, Volume: 99, Issue:3

    Topics: Animals; Arteriovenous Shunt, Surgical; Blood Pressure; Cardiac Output; Dogs; Fibrinolysis; Hydralaz

1991
Vasodilator therapy in microembolic porcine pulmonary hypertension.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:1

    Topics: Alprostadil; Animals; Ferricyanides; Hemodynamics; Hydralazine; Hypertension, Pulmonary; Infusions,

1990
Effects of vasodilators on gas exchange in acute canine embolic pulmonary hypertension.
    Anesthesiology, 1990, Volume: 72, Issue:1

    Topics: Acute Disease; Alprostadil; Animals; Dogs; Hydralazine; Hypertension, Pulmonary; Nitroprusside; Pulm

1990
Efficacy of vasodilator therapy in canine model of acute pulmonary hypertension.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Alprostadil; Animals; Coronary Circulation; Disease Models, Animal; Dogs; Female; Heart Ventricles;

1988
Pulmonary vascular effects of hydralazine in a canine preparation of pulmonary thromboembolism.
    Circulation, 1986, Volume: 73, Issue:5

    Topics: Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Hemodynamics; Hydralazine; Hy

1986