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hydralazine and Pregnancy

hydralazine has been researched along with Pregnancy in 316 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"The objectives were to compare the efficacy and safety of intravenous hydralazine and labetalol for acutely lowering severe hypertension in pregnancy."9.51Comparison of intravenous labetalol and hydralazine for severe hypertension in pregnancy in Northeastern Nigeria: A randomized controlled trial. ( Bako, B; Dawha, YM; Muhammad, S; Usman, H; Yahya, A; Yekeen, A, 2022)
"We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy."9.24Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017)
"This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy."9.22Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022)
"We evaluated 16 pregnant women with gestational age between 20 and 32 weeks in acute severe hypertension which were randomly allocated to receive either hydralazine or labetalol."9.15Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial. ( Baggio, MR; Berezowski, AT; Calderon, AC; Cavalli, RC; Duarte, G; Marcolin, AC; Martins, WP, 2011)
"Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy."9.15Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy. ( Esmaeili, S; Khazaeipour, Z; Motevalian, M; Pourmojieb, M; Rezaei, Z; Sharbaf, FR; Youefzadeh-Fard, Y, 2011)
"Diazoxide is one of few available agents for treatment of hypertensive emergencies in pregnancy."9.12A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial. ( Child, A; Gillin, AG; Henderson-Smart, DJ; Hennessy, A; Makris, A; Ogle, RF; Thornton, CE, 2007)
"Nifedipine is safe and more effective than hydralazine in controlling blood pressure in severe pre-eclampsia."9.10Nifedipine or hydralazine as a first-line agent to control hypertension in severe preeclampsia. ( Aali, BS; Nejad, SS, 2002)
"Although hydralazine has been the drug of choice for treating pregnancy-induced hypertension for some time owing to its effect on peripheral vascular tonus, its effects on utero- and feto-placental circulation are less well understood."9.08Effects of hydralazine on placental and renal circulation in pre-eclampsia. ( Gennser, G; Gudmundsson, S; Marsal, K, 1995)
"To compare ketanserin with hydralazine in the treatment of hypertension in late pregnancy."9.08Ketanserin and hydralazine in hypertension in pregnancy--a randomised double-blind trial. ( Howarth, G; Odendaal, HJ; Rossouw, HJ, 1995)
"The purposes of this study were to compare the efficacy of sublingual nifedipine with intravenous hydrallazine in the control of acute hypertension of pregnancy and to make a preliminary assessment whether sublingual nifedipine could be recommended for use by midwives faced with severe hypertension in pregnancy in a rural setting."9.08Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996)
"The objective was to compare the fetal and maternal effects between parenteral hydralazine and sublingual nifedipine used like antihypertensive drugs in the management of severe preeclampsia."9.07[Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents]. ( Flores Padilla, LM; Walss Rodriguez, RJ, 1993)
"Labetalol (Trandate; Allen & Hanburys), a combined alpha- and beta-adrenergic blocking agent, was compared with the more commonly used peripheral vasodilator, dihydrallazine (Nepresol; Ciba), each administered as an infusion, in the treatment of severe hypertension in 20 primigravidas at greater than or equal to 32 weeks' gestation."9.06Comparison of labetalol and dihydralazine in hypertensive emergencies of pregnancy. ( Ashe, RG; Moodley, J; Philpott, RH; Richards, AM, 1987)
"Forty-four consecutive patients referred for treatment because of hypertension (greater than 150/90 mmHg) occurring during pregnancy were randomly allocated to one of two treatment groups, hydralazine alone (n = 21) or hydralazine combined with pindolol (n = 23)."9.06Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol. ( Boner, G; Bott-Kanner, G; Friedman, S; Merlob, P; Nissenkorn, A; Ovadia, J; Paran, E; Reisner, S; Rosenfeld, J; Zmora, E, 1986)
"Patients with acute pregnancy-related hypertension were randomized to treatment with 200 mg oral labetalol or 10 mg intramuscular hydralazine."9.05Treatment of acute pregnancy-related hypertension: labetalol and hydralazine compared. ( Calder, AA; Greer, I; Walker, JJ, 1983)
"The effect of intravenous infusion of labetalol and of dihydralazine in increasing doses was compared in 12 women with severe hypertension in pregnancy."9.05Intravenous labetalol and intravenous dihydralazine in severe hypertension in pregnancy. ( Davey, DA; Dommisse, J; Garden, A, 1982)
"Twentysix women with pregnancy-induced hypertension have been randomly treated with either labetalol or Aldomet."9.05Comparison of the alpha and beta blocking drug, labetalol, and methyl dopa in the treatment of moderate and severe pregnancy-induced hypertension. ( Broughton Pipkin, F; Lamming, GD; Symonds, EM, 1980)
"In an open, controlled trial, treatment with a combination of metoprolol and hydralazine was compared with non-pharmacological management of mild and moderate hypertension in pregnancy."9.05A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy. ( Axelsson, O; Högstedt, S; Lindberg, BS; Lindeberg, S; Lindmark, G; Rane, A; Sandström, B, 1985)
" Control of hypertension was equivalent in both treatment groups, and in 64 (35%) cases hydralazine had to be added to the treatment to achieve the therapeutic goal (diastolic blood pressure below 85 mm Hg)."9.05Antihypertensive treatment in pregnancy: analysis of different responses to oxprenolol and methyldopa. ( Gallery, ED; Gyory, AZ; Ross, MR, 1985)
" Plasma renin activity (PRA), the daily urinary excretion of aldosterone (dU-Aldo) and electrolytes were studied before and during dihydralazine therapy (25 mg 3 times daily)."9.04The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy. ( Lammintausta, R, 1978)
"To review outcomes in randomised controlled trials comparing hydralazine against other antihypertensives for severe hypertension in pregnancy."8.82Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis. ( Cham, C; Magee, LA; Ohlsson, A; von Dadelszen, P; Waterman, EJ, 2003)
"Tradiational drug therapy choices for hypertension in pregnancy continue to be hydralazine for acute reduction of blood pressure and methyldopa for the management of chronic hypertension."8.79Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994)
"To compare the efficacy of intravenous Labetalol and intravenous Hydralazine in reduction of blood pressure in patients with severe pre-eclampsia."8.31Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women. ( Husain, S; Hussain, R; Kausar, M, 2023)
"Gestational hydralazine reduced renal global DNA methylation in offspring of obese mothers and attenuated maternal obesity-induced renal fibrosis."8.02Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet. ( Chen, H; Glastras, SJ; Hou, M; Larkin, BP; Nguyen, LT; Pollock, CA; Saad, S; Wang, R, 2021)
"Hydralazine, an antihypertensive agent used during pregnancy, undergoes N-acetylation primarily via N-acetyltransferase 2 (NAT2) to form 3-methyl-1,2,4-triazolo[3,4-a]phthalazine (MTP)."7.91Effect of N-Acetyltransferase 2 Genotype on the Pharmacokinetics of Hydralazine During Pregnancy. ( Cusumano, M; Easterling, TR; Han, LW; Hebert, MF; Phillips, BR; Risler, LJ; Ryu, RJ; Shen, DD, 2019)
"We describe a novel ER+ breast cancer model to study de novo and acquired tamoxifen (TAM) resistance."7.85Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model. ( Bouker, KB; Clarke, R; Cook, KL; Cruz, MI; de Assis, S; Hilakivi-Clarke, L; Hu, R; Jin, L; Nguyen, N; Wang, X; Wang, Y; Wärri, A; Wehrenberg, B; Xuan, J; Zhang, X; Zwart, A, 2017)
"Antihypertensive drugs such as clonidine, diazoxide, hydralazine and furosemide are used in the hypertensive disorders of pregnancy to control blood pressure, but it is not clear if they modulate the production of placental or circulating cytokines."7.73Antihypertensive drugs clonidine, diazoxide, hydralazine and furosemide regulate the production of cytokines by placentas and peripheral blood mononuclear cells in normal pregnancy. ( Hennessy, A; Horvath, JS; Makris, A; Ogle, R; Thornton, C; Xu, B, 2006)
"To audit the use of bolus hydralazine for control of severe hypertension within a protocol for the management of severe pre-eclampsia."7.69Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia. ( de Swiet, M; Paterson-Brown, S; Redfern, N; Robson, SC; Walkinshaw, SA, 1994)
" Cyclic GMP concentrations were also determined in 12 women with severe pre-eclampsia before and after treatment with hydralazine."7.69Cyclic guanosine 3',5' monophosphate concentrations in pre-eclampsia: effects of hydralazine. ( Calle, A; Jácome, P; López-Jaramillo, P; Narváez, M; Nava, E; Rivera, J; Ruano, C, 1996)
" This study was undertaken in gravid ewes to determine the effects of treatment of cocaine-induced hypertension with hydralazine (Apresoline) on the maternal and fetal cardiovascular systems, catecholamine response, blood gas and acid-base status, and uterine blood flow (UBF)."7.68Hydralazine does not restore uterine blood flow during cocaine-induced hypertension in the pregnant ewe. ( Espinoza, MI; Hughes, SC; Johnson, JL; Messer, CP; Parer, JT; Rosen, MA; Shnider, SM; Vertommen, JD, 1992)
"Acute cocaine intoxication has been associated with elevated blood pressure and placental abruption."7.68Cocaine intoxication associated with abruptio placentae. ( Clark, JF; Flowers, D; Westney, LS, 1991)
" The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension."7.67Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report. ( Bar-Khayim, Y; Dgani, R; Lancet, M; Mogilner, BM; Nissim, F; Shoham, Z; Yemini, M, 1989)
"The apex cardiogram and its 1st differential quotient were simultaneously registered with the phonocardiogram, the electrocardiogram and the curve of the carotid pulse in 10 female patients with pregnancy-induced hypertension before and after the therapy with dihydralazine sulphate."7.67[Studies of heart function using apex cardiography in pregnancy-induced hypertension before and following therapy with dihydralazine sulfate]. ( Benndorf, S; Kehrbein, C; Nahrendorf, W; Rading, A; Steinig, G; Weidler, B, 1986)
"The hemodynamic changes after intravenous administration of hydralazine were assessed using M-mode echocardiography in 13 pregnant patients with severe hypertension."7.67Hemodynamic effects of intravenous hydralazine in pregnant women with severe hypertension. ( Kuzniar, J; Piela, A; Skret, A; Szmigiel, Z; Zaczek, T, 1985)
"The uteroplacental blood flow was measured in 12 women with hypertension during pregnancy before and after intravenous injection of dihydralazine."7.66Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy. ( Lewander, R; Lunell, NO; Nylund, L; Sarby, B; Thornström, S, 1983)
"A combination of propranolol and hydrallazine was administered to 13 patients with longstanding hypertension during 15 pregnancies."7.66Propranolol and hydrallazine in the management of essential hypertension in pregnancy. ( Bott-Kanner, G; Joel-Cohen, SJ; Reisner, SH; Rosenfeld, JB; Schweitzer, A, 1980)
"Hydralazine was found to be superior in its ability to effect more rapidly a lower mean arterial blood pressure."6.66Utilization of hydralazine or alpha-methyldopa for the management of early puerperal hypertension. ( Griffis, KR; Martin, JN; Martin, RW; Morrison, JC; Palmer, SM, 1989)
" The duration of action also varied in the labetalol group, with the shortest duration occurring in those patients who required the highest dosage for BP control."6.66A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy. ( Amon, E; Gonzalez, AR; Mabie, WC; Sibai, BM, 1987)
"Magnesium sulfate was promptly administered on admission to every woman to prevent seizure."5.56Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women. ( Chera-Aree, P; Leetheeragul, J; Sampaojarean, U; Surasereewong, S; Tengtrakulcharoen, P; Wataganara, T, 2020)
"The objectives were to compare the efficacy and safety of intravenous hydralazine and labetalol for acutely lowering severe hypertension in pregnancy."5.51Comparison of intravenous labetalol and hydralazine for severe hypertension in pregnancy in Northeastern Nigeria: A randomized controlled trial. ( Bako, B; Dawha, YM; Muhammad, S; Usman, H; Yahya, A; Yekeen, A, 2022)
" Experimental data suggests that hydralazine, given concomitantly, attenuates the development of hemodynamic tolerance to ISDN and may increase bioavailability of NO in the vasculature."5.35Isosorbide dinitrate/hydralazine: its role in the treatment of heart failure. ( Jacob, RG; Thadani, U, 2008)
"Twenty mothers with moderate to severe preeclampsia were allocated to labetalol (Trandate) or hydralazine (Apresolin) antihypertensive treatment."5.29Neonatal adaptation in hypertensive pregnancy--a study of labetalol vs hydralazine treatment. ( Faxelius, G; Hjertberg, R; Lagercrantz, H, 1993)
"Treatment with propranolol and hydralazine was effective in controlling her blood pressure and was continued throughout her next two pregnancies, both of which were successful."5.26Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report. ( Bott-Kanner, G; Joel-Cohen, J; Rosenfeld, JB; Schoenfeld, A; Schweitzer, A, 1978)
"We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy."5.24Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017)
"This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy."5.22Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022)
"Hydralazine is a vasodilator used to treat hypertension, pre-eclampsia, and heart failure."5.22A review on the clinical pharmacokinetics of hydralazine. ( Alqahtani, F; Ashraf, W; Hussain, I; Imran, I; Khalid, S; Majeed, A; Rasool, MF; Rehman, AU; Saeed, H; Shahzad Qamar, A; Zamir, A, 2022)
"We evaluated 16 pregnant women with gestational age between 20 and 32 weeks in acute severe hypertension which were randomly allocated to receive either hydralazine or labetalol."5.15Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial. ( Baggio, MR; Berezowski, AT; Calderon, AC; Cavalli, RC; Duarte, G; Marcolin, AC; Martins, WP, 2011)
"Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy."5.15Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy. ( Esmaeili, S; Khazaeipour, Z; Motevalian, M; Pourmojieb, M; Rezaei, Z; Sharbaf, FR; Youefzadeh-Fard, Y, 2011)
"Diazoxide is one of few available agents for treatment of hypertensive emergencies in pregnancy."5.12A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial. ( Child, A; Gillin, AG; Henderson-Smart, DJ; Hennessy, A; Makris, A; Ogle, RF; Thornton, CE, 2007)
"Nifedipine is safe and more effective than hydralazine in controlling blood pressure in severe pre-eclampsia."5.10Nifedipine or hydralazine as a first-line agent to control hypertension in severe preeclampsia. ( Aali, BS; Nejad, SS, 2002)
"Although hydralazine has been the drug of choice for treating pregnancy-induced hypertension for some time owing to its effect on peripheral vascular tonus, its effects on utero- and feto-placental circulation are less well understood."5.08Effects of hydralazine on placental and renal circulation in pre-eclampsia. ( Gennser, G; Gudmundsson, S; Marsal, K, 1995)
"To compare ketanserin with hydralazine in the treatment of hypertension in late pregnancy."5.08Ketanserin and hydralazine in hypertension in pregnancy--a randomised double-blind trial. ( Howarth, G; Odendaal, HJ; Rossouw, HJ, 1995)
"Fifty-one women with pregnancy-induced hypertension (PIH) were randomly allocated to one of three treatment groups: A: hydralazine (13); B: hydralazine and propranolol (17); and C: hydralazine and pindolol (19)."5.08Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension. ( Holzberg, G; Insler, V; Mazor, M; Paran, E; Zmora, E, 1995)
"The purposes of this study were to compare the efficacy of sublingual nifedipine with intravenous hydrallazine in the control of acute hypertension of pregnancy and to make a preliminary assessment whether sublingual nifedipine could be recommended for use by midwives faced with severe hypertension in pregnancy in a rural setting."5.08Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996)
"The objective was to compare the fetal and maternal effects between parenteral hydralazine and sublingual nifedipine used like antihypertensive drugs in the management of severe preeclampsia."5.07[Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents]. ( Flores Padilla, LM; Walss Rodriguez, RJ, 1993)
"Labetalol (Trandate; Allen & Hanburys), a combined alpha- and beta-adrenergic blocking agent, was compared with the more commonly used peripheral vasodilator, dihydrallazine (Nepresol; Ciba), each administered as an infusion, in the treatment of severe hypertension in 20 primigravidas at greater than or equal to 32 weeks' gestation."5.06Comparison of labetalol and dihydralazine in hypertensive emergencies of pregnancy. ( Ashe, RG; Moodley, J; Philpott, RH; Richards, AM, 1987)
"Forty-four consecutive patients referred for treatment because of hypertension (greater than 150/90 mmHg) occurring during pregnancy were randomly allocated to one of two treatment groups, hydralazine alone (n = 21) or hydralazine combined with pindolol (n = 23)."5.06Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol. ( Boner, G; Bott-Kanner, G; Friedman, S; Merlob, P; Nissenkorn, A; Ovadia, J; Paran, E; Reisner, S; Rosenfeld, J; Zmora, E, 1986)
"Patients with acute pregnancy-related hypertension were randomized to treatment with 200 mg oral labetalol or 10 mg intramuscular hydralazine."5.05Treatment of acute pregnancy-related hypertension: labetalol and hydralazine compared. ( Calder, AA; Greer, I; Walker, JJ, 1983)
"The effect of intravenous infusion of labetalol and of dihydralazine in increasing doses was compared in 12 women with severe hypertension in pregnancy."5.05Intravenous labetalol and intravenous dihydralazine in severe hypertension in pregnancy. ( Davey, DA; Dommisse, J; Garden, A, 1982)
"Twentysix women with pregnancy-induced hypertension have been randomly treated with either labetalol or Aldomet."5.05Comparison of the alpha and beta blocking drug, labetalol, and methyl dopa in the treatment of moderate and severe pregnancy-induced hypertension. ( Broughton Pipkin, F; Lamming, GD; Symonds, EM, 1980)
"In an open, controlled trial, treatment with a combination of metoprolol and hydralazine was compared with non-pharmacological management of mild and moderate hypertension in pregnancy."5.05A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy. ( Axelsson, O; Högstedt, S; Lindberg, BS; Lindeberg, S; Lindmark, G; Rane, A; Sandström, B, 1985)
" Control of hypertension was equivalent in both treatment groups, and in 64 (35%) cases hydralazine had to be added to the treatment to achieve the therapeutic goal (diastolic blood pressure below 85 mm Hg)."5.05Antihypertensive treatment in pregnancy: analysis of different responses to oxprenolol and methyldopa. ( Gallery, ED; Gyory, AZ; Ross, MR, 1985)
" Plasma renin activity (PRA), the daily urinary excretion of aldosterone (dU-Aldo) and electrolytes were studied before and during dihydralazine therapy (25 mg 3 times daily)."5.04The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy. ( Lammintausta, R, 1978)
" Oral nifedipine is now considered an alternative first-line therapy, along with intravenous hydralazine and labetalol for women presenting with pre-eclampsia."4.98Focused Update on Pharmacologic Management of Hypertensive Emergencies. ( Broscious, R; Devabhakthuni, S; Noel, ZR; Watson, K, 2018)
"The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy."4.98Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018)
"Oral nifedipine, and possibly labetalol and methyldopa, are suitable options for treatment of severe hypertension in pregnancy/postpartum."4.90Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review. ( Firoz, T; Gordon, R; MacDonell, K; Magee, LA; Payne, BA; Vidler, M; von Dadelszen, P, 2014)
"To review outcomes in randomised controlled trials comparing hydralazine against other antihypertensives for severe hypertension in pregnancy."4.82Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis. ( Cham, C; Magee, LA; Ohlsson, A; von Dadelszen, P; Waterman, EJ, 2003)
"Tradiational drug therapy choices for hypertension in pregnancy continue to be hydralazine for acute reduction of blood pressure and methyldopa for the management of chronic hypertension."4.79Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994)
" It has also been used intravenously in phaeochromocytoma, tetanus, clonidine withdrawal, and as an adjunct to halothane to produce hypotensive anaesthesia."4.76Combined alpha- and beta-receptor inhibition in the treatment of hypertension. ( Prichard, BN, 1984)
"To compare the efficacy of intravenous Labetalol and intravenous Hydralazine in reduction of blood pressure in patients with severe pre-eclampsia."4.31Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women. ( Husain, S; Hussain, R; Kausar, M, 2023)
"A retrospective cohort study of patients with severe peripartum hypertension (systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥ 110 mm Hg confirmed within 15 min) to determine whether the effectiveness of blood pressure control using nationally recommended medications (hydralazine, labetalol, nifedipine) differed by race/ethnicity."4.12Race/ethnicity differences in response to acute antihypertensive treatment of peripartum severe hypertension. ( Greene, NH; Kilpatrick, SJ; Pon, FF, 2022)
"Gestational hydralazine reduced renal global DNA methylation in offspring of obese mothers and attenuated maternal obesity-induced renal fibrosis."4.02Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet. ( Chen, H; Glastras, SJ; Hou, M; Larkin, BP; Nguyen, LT; Pollock, CA; Saad, S; Wang, R, 2021)
" The American College of Obstetricians and Gynecologists recommends that acute-onset, severe hypertension be treated with first line-therapy (intravenous labetalol, intravenous hydralazine or oral nifedipine) within 60 minutes to reduce risk of maternal morbidity and death."3.96Identification of factors associated with delayed treatment of obstetric hypertensive emergencies. ( Akerman, MB; Elsayad, A; Halpern, TA; Heiselman, CJ; Heo, HJ; Kantorowska, A; Muscat, JC; Sicuranza, GB; Vintzileos, AM, 2020)
"We describe a novel ER+ breast cancer model to study de novo and acquired tamoxifen (TAM) resistance."3.85Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model. ( Bouker, KB; Clarke, R; Cook, KL; Cruz, MI; de Assis, S; Hilakivi-Clarke, L; Hu, R; Jin, L; Nguyen, N; Wang, X; Wang, Y; Wärri, A; Wehrenberg, B; Xuan, J; Zhang, X; Zwart, A, 2017)
"To determine whether the incidence of hypotension or adverse fetal heart tracing (FHT) category change differed following antepartum administration of intravenous (IV) labetalol versus hydralazine."3.83Risks of parenteral antihypertensive therapy for the treatment of severe maternal hypertension are low. ( Aghajanian, P; Greene, N; Kilpatrick, SJ; Rodriguez, M; Sharma, KJ, 2016)
" Given her undifferentiated headache and the possibility of preeclampsia, the patient was treated with magnesium sulfate, which was subsequently stopped due to worsening bradycardia."3.81Late Postpartum Eclampsia with Postpartum Angiopathy: An Uncommon Diagnosis in the Emergency Department. ( Dickman, E; Garg, D; Rahaman, B; Stein, EG, 2015)
"We studied the effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam (a dopamine D1-agonist) on isolated human umbilical arteries (HUA) from patients classified as normotensive and with pregnancy-induced hypertension (PIH)."3.72The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. ( Arias, ME; Levy, JH; Sato, N; Szlam, F; Tanaka, KA; Tsuda, A, 2003)
"These findings demonstrate that agents commonly used for the treatment of hypertensive disease in pregnancy, excluding alpha-methyldopa, have significant direct effects on the feto-placental circulation."3.72Anti-hypertensive therapy and the feto-placental circulation: effects on umbilical artery resistance. ( Dennedy, MC; Houlihan, DD; Morrison, JJ; Ravikumar, N, 2004)
" With the exception of one subject, all pre-eclamptics were taking clonidine (a known suppressant of rapid eye movement-REM-sleep) for control of their hypertension."3.70Pre-eclampsia is associated with marked alterations in sleep architecture. ( Blyton, CM; Edwards, N; Kesby, GJ; Sullivan, CE; Wilcox, I, 2000)
"To audit the use of bolus hydralazine for control of severe hypertension within a protocol for the management of severe pre-eclampsia."3.69Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia. ( de Swiet, M; Paterson-Brown, S; Redfern, N; Robson, SC; Walkinshaw, SA, 1994)
" Cyclic GMP concentrations were also determined in 12 women with severe pre-eclampsia before and after treatment with hydralazine."3.69Cyclic guanosine 3',5' monophosphate concentrations in pre-eclampsia: effects of hydralazine. ( Calle, A; Jácome, P; López-Jaramillo, P; Narváez, M; Nava, E; Rivera, J; Ruano, C, 1996)
" This study was undertaken in gravid ewes to determine the effects of treatment of cocaine-induced hypertension with hydralazine (Apresoline) on the maternal and fetal cardiovascular systems, catecholamine response, blood gas and acid-base status, and uterine blood flow (UBF)."3.68Hydralazine does not restore uterine blood flow during cocaine-induced hypertension in the pregnant ewe. ( Espinoza, MI; Hughes, SC; Johnson, JL; Messer, CP; Parer, JT; Rosen, MA; Shnider, SM; Vertommen, JD, 1992)
"Acute cocaine intoxication has been associated with elevated blood pressure and placental abruption."3.68Cocaine intoxication associated with abruptio placentae. ( Clark, JF; Flowers, D; Westney, LS, 1991)
" The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension."3.67Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report. ( Bar-Khayim, Y; Dgani, R; Lancet, M; Mogilner, BM; Nissim, F; Shoham, Z; Yemini, M, 1989)
"Echocardiography documented fetal premature atrial contractions after maternal hydralazine treatment for hypertension."3.67Fetal premature atrial contractions associated with hydralazine. ( Feinstein, SJ; Lodeiro, JG; Lodeiro, SB, 1989)
" To test if these structural changes occur in the absence of raised blood pressure, hydralazine was administered to spontaneously hypertensive rats and normotensive controls prior to and during pregnancy (100 ml/l drinking water), and to the newborn males up to 21 weeks of age (16."3.67Prenatal and postnatal hydralazine treatment does not prevent renal vessel wall thickening in SHR despite the absence of hypertension. ( Forrest, JB; Lee, RM; Smeda, JS, 1988)
"The apex cardiogram and its 1st differential quotient were simultaneously registered with the phonocardiogram, the electrocardiogram and the curve of the carotid pulse in 10 female patients with pregnancy-induced hypertension before and after the therapy with dihydralazine sulphate."3.67[Studies of heart function using apex cardiography in pregnancy-induced hypertension before and following therapy with dihydralazine sulfate]. ( Benndorf, S; Kehrbein, C; Nahrendorf, W; Rading, A; Steinig, G; Weidler, B, 1986)
"The hemodynamic changes after intravenous administration of hydralazine were assessed using M-mode echocardiography in 13 pregnant patients with severe hypertension."3.67Hemodynamic effects of intravenous hydralazine in pregnant women with severe hypertension. ( Kuzniar, J; Piela, A; Skret, A; Szmigiel, Z; Zaczek, T, 1985)
"The uteroplacental blood flow was measured in 12 women with hypertension during pregnancy before and after intravenous injection of dihydralazine."3.66Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy. ( Lewander, R; Lunell, NO; Nylund, L; Sarby, B; Thornström, S, 1983)
"The effects on the fetus of the acute lowering of blood pressure in maternal hypertension with dihydralazine 6."3.66The effect of low-dose dihydrallazine on the fetus in the emergency treatment of hypertension in pregnancy. ( Moodley, J; Vink, GJ, 1982)
"The concentration of "real" and "apparent" (= "real" hydralazine + acid-labile hydrazones) hydralazine in maternal and umbilical plasma obtained at delivery of 6 women treated with hydralazine and atenolol for pregnancy hypertension were measured by gas chromatography."3.66Transplacental passage and breast milk concentrations of hydralazine. ( Hanson, A; Ingemarsson, I; Liedholm, H; Melander, A; Wåhlin-Boll, E, 1982)
"A combination of propranolol and hydrallazine was administered to 13 patients with longstanding hypertension during 15 pregnancies."3.66Propranolol and hydrallazine in the management of essential hypertension in pregnancy. ( Bott-Kanner, G; Joel-Cohen, SJ; Reisner, SH; Rosenfeld, JB; Schweitzer, A, 1980)
"During phenylephrine-induced hypertension in 6 near-term pregnant ewes, nitroprusside rapidly lowered the blood pressure to control values with no accompanying change in uterine blood flow."3.65Comparison of nitroprusside and hydralazine in hypertensive pregnant ewes. ( Krames, E; Levinson, G; Ring, G; Shnider, SM; Wallis, KL, 1977)
"Since 1955 standardized treatment applied uniformly to all cases of eclampsia at Parkland Memorial Hospital has consisted of (1) magnesium sulfate intravenously and intramuscularly to control convulsions, (2) intravenous hydralazine intermittently to lower diastolic blood pressure when it exceeded 110 mm."3.65Standardized treatment of 154 consecutive cases of eclampsia. ( Pritchard, JA; Pritchard, SA, 1975)
"An active approach to the management of severe pre-eclampsia is outlined using sedation with diazepam, hypotensive therapy with hydralazine and immediate steps to terminate the pregnancy."3.65Active management of severe pre-eclampsia. ( Baskett, TF; Bradford, CR, 1973)
"Hydralazine was found to be superior in its ability to effect more rapidly a lower mean arterial blood pressure."2.66Utilization of hydralazine or alpha-methyldopa for the management of early puerperal hypertension. ( Griffis, KR; Martin, JN; Martin, RW; Morrison, JC; Palmer, SM, 1989)
" The duration of action also varied in the labetalol group, with the shortest duration occurring in those patients who required the highest dosage for BP control."2.66A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy. ( Amon, E; Gonzalez, AR; Mabie, WC; Sibai, BM, 1987)
"The incidence of neonatal jaundice was higher in the control group (P less than 0."2.66Lumbar epidural analgesia in hypertensive patients during labour. ( Lachman, E; Neri, A; Nitke, S; Ovadia, J, 1986)
"The incidence of preeclampsia in the randomized prophylactic antihypertensive group was statistically lower than that in the nonrandomized group (8."2.65The effects of prophylactic management and therapeutics on hypertensive disease in pregnancy: preliminary studies. ( Crenshaw, MC; Dorminy, JH; Gall, SA; Jelovsek, FR; Welt, SI, 1981)
"Preeclampsia is characterized by blood pressure greater than 140/90 mmHg in the second half of pregnancy."2.55Pathophysiology and Current Clinical Management of Preeclampsia. ( Amaral, LM; LaMarca, B; Owens, M; Wallace, K, 2017)
"Risk factors for the development of preeclampsia include microvascular diseases, such as diabetes mellitus; vascular and connective tissue disorders; hypertension; antiphospholipid antibody syndrome; and nephropathy."2.45Pharmacotherapeutic options for the treatment of preeclampsia. ( Baldwin, K; McCoy, S, 2009)
"Marfan syndrome is an inheritable connective tissue disorder with multisystem involvement and variable expression of signs and symptoms, caused by mutations within the fibrillin gene on chromosome 15q21."2.43Pregnancy in Marfan syndrome after aortic root replacement: a case report and review of the literature. ( Elami, A; Ezra, Y; Gilon, D; Ginosar, Y; Pollak, A; Volach, V, 2006)
"Management of preeclampsia is bed rest, aspirin administration, antihypertensive agents (beta-blockers, hydralazine, alpha-methyldopa) would be used for reduction of blood pressure."2.40[Pregnancy induced hypertension]. ( Suzuki, H, 1997)
"Hypertension in pregnancy has implications for both maternal and fetal welfare."2.37Hypertension in pregnancy. Pathophysiology and management. ( Lubbe, WF, 1984)
"Although hypertension is the most common and significant risk factor in pregnancy, the risks can be minimized with careful supervision and therapy."2.37Hypertension in pregnant women. ( Gallery, ED, 1985)
"Hydralazine was administered in daily doses of 50 mg, starting 24-36 h after the initial diagnosis of EUVI and continuing throughout the first trimester."1.72First-trimester miscarriage rate decreases with hydralazine therapy in pregnancies with early uterine vascular insufficiency: a cohort study. ( Biron, M; Canals, A; Castiglione, A; Faundez, R; Leible, S; Mitelman, G; Sepulveda, W; Walton, R, 2022)
"Magnesium sulfate was promptly administered on admission to every woman to prevent seizure."1.56Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women. ( Chera-Aree, P; Leetheeragul, J; Sampaojarean, U; Surasereewong, S; Tengtrakulcharoen, P; Wataganara, T, 2020)
"Heart failure is an established predictor of primary cardiac events during pregnancy."1.40Treatment of pre-existing cardiomyopathy during pregnancy. ( Ascoop, AK; De Backer, J; De Pauw, M; Gevaert, S; Roelens, K; Tromp, F, 2014)
"Postpartum preeclampsia/eclampsia is the presence of hypertension and proteinuria, with or without seizures, occurring up to 4 weeks after delivery."1.37Postpartum preeclampsia: emergency department presentation and management. ( Abbott, J; Bakes, K; Withers, E; Yancey, LM, 2011)
" Experimental data suggests that hydralazine, given concomitantly, attenuates the development of hemodynamic tolerance to ISDN and may increase bioavailability of NO in the vasculature."1.35Isosorbide dinitrate/hydralazine: its role in the treatment of heart failure. ( Jacob, RG; Thadani, U, 2008)
"Mean IL-18 levels were lower in preeclampsia than in controls (185 +/- 74 pg/mL vs 224 +/- 75 pg/mL, P =."1.32Interleukin-18 in the plasma of women with preeclampsia. ( Adams, KM; Atkinson, MW; Guthrie, KA; Mandel, LS, 2003)
"Coincident with the preeclampsia was a postdural puncture headache complicating the diagnosis of late postpartum preeclampsia."1.32Late postpartum eclampsia coincident with postdural puncture headache: a case report. ( Norman, D; Winston, AW, 2003)
"Enalapril treatment resulted in a 24% mortality, reduced body weight, and decreased heart weight (p < 0."1.31Angiotensin converting enzyme inhibition decreases cell turnover in the neonatal rat heart. ( Cheon, HW; Choi, JH; Hong, YS; Kim, CH; Kim, KB; Kim, SK; Lee, JW; Yoo, KH, 2002)
"3 U/MPL), mild preeclampsia (6."1.30Anticardiolipin antibodies and the severity of preeclampsia-eclampsia. ( Cortés-Llamas, V; González-Ortiz, M; Martínez-Abundis, E; Salazar-Páramo, M, 1999)
"Twenty mothers with moderate to severe preeclampsia were allocated to labetalol (Trandate) or hydralazine (Apresolin) antihypertensive treatment."1.29Neonatal adaptation in hypertensive pregnancy--a study of labetalol vs hydralazine treatment. ( Faxelius, G; Hjertberg, R; Lagercrantz, H, 1993)
"We present a case of acute renal failure due to severe preeclampsia successfully treated with the infusion of a low dose of dopamine."1.29Low-dose dopamine in treating acute renal failure caused by preeclampsia. ( Anai, T; Miyakawa, I; Nasu, K; Yoshimatsu, J, 1996)
"Hydralazine was then administered; the effects on regional resistance and blood flow were evaluated with a radionuclide-labeled microsphere technique."1.28Differential effects of intravenous hydralazine on myoendometrial and placental blood flow in hypertensive pregnant ewes. ( Barnard, JM; Henry, JB; Pedron, SL; Phernetton, TM; Rankin, JH; Reid, DL, 1992)
"Hydralazine failed to inhibit responses to any of the agonists tested in the fetal and maternal arteries."1.28Effects of vasodilators on isolated human uteroplacental arteries. ( Allen, J; Forman, A; Maigaard, S; Skajaa, K, 1991)
"Hydralazine to lower the diastolic blood pressure somewhat, when it was 110 mm Hg or higher, prevented intracranial hemorrhage."1.27The Parkland Memorial Hospital protocol for treatment of eclampsia: evaluation of 245 cases. ( Cunningham, FG; Pritchard, JA; Pritchard, SA, 1984)
"1-4%, w/w) in three separate experiments: (1) a 2-week dose-response study; (2) a 2-month long-term feeding study; and (3) a pregnancy study."1.27Effect of the antihypertensive drug hydralazine on mineral metabolism in the rat. ( Keen, CL; Lönnerdal, B; Peters, JM, 1988)
"A case of severe preeclampsia in which hemolysis and rapid platelet consumption persisted after delivery, but in which the blood urea nitrogen and serum glutamic oxaloacetic acid transaminase levels returned to normal is presented."1.27Severe preeclampsia with persistent postpartum hemolysis and thrombocytopenia treated by plasmapheresis. ( Brenner, W; Schwartz, ML, 1985)
"Pregnancies complicated by severe preeclampsia in the second trimester are associated with a high incidence of perinatal morbidity and mortality."1.27Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester. ( Abdella, TN; Anderson, GD; Brooks, TF; Sibai, BM; Spinnato, JA; Taslimi, M, 1985)
"Autonomic hyperreflexia is a serious peripartum complication associated with spinal cord lesions."1.27Management of autonomic hyperreflexia associated with a low thoracic spinal cord lesion. ( Gimovsky, ML; Ojeda, A; Ozaki, R; Zerne, S, 1985)
"Although the recognition and treatment of preeclampsia theoretically should eliminate eclampsia, it has not disappeared and remains a substantial threat to maternal and fetal well-being."1.26Eclampsia: treatment and referral. ( Anderson, GD; Dilts, PV; McCubbin, JH; Sibai, BM, 1982)
"Pregnancy-related hypertension is not thought to be an absolute contraindication to glucocorticoid therapy for the induction of pulmonary maturity."1.26Glucocorticoid therapy for the induction of pulmonary maturity in severely hypertensive gravid women. ( Nochimson, DJ; Petrie, RH, 1979)
"Treatment with propranolol and hydralazine was effective in controlling her blood pressure and was continued throughout her next two pregnancies, both of which were successful."1.26Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report. ( Bott-Kanner, G; Joel-Cohen, J; Rosenfeld, JB; Schoenfeld, A; Schweitzer, A, 1978)

Research

Studies (316)

TimeframeStudies, this research(%)All Research%
pre-1990194 (61.39)18.7374
1990's44 (13.92)18.2507
2000's28 (8.86)29.6817
2010's35 (11.08)24.3611
2020's15 (4.75)2.80

Authors

AuthorsStudies
Wu, HZ1
Cheng, Y1
Yu, D1
Li, JB1
Jiang, YF1
Zhu, ZN1
Muhammad, S1
Usman, H1
Dawha, YM1
Yahya, A1
Yekeen, A1
Bako, B1
Greene, NH1
Pon, FF1
Kilpatrick, SJ4
Taguchi, R1
Shigemi, D1
Yasunaga, H1
Wautlet, CK1
Hoffman, MC1
Shahzad Qamar, A1
Zamir, A1
Khalid, S1
Ashraf, W1
Imran, I1
Hussain, I1
Rehman, AU1
Saeed, H1
Majeed, A1
Alqahtani, F1
Rasool, MF1
Kim, MK1
Choe, KR1
Jeong, DE1
Lee, KN1
Cho, I1
Kim, HJ1
Park, JY1
S, D1
Novri, DA1
Hamidy, Y1
Savira, M1
Kausar, M1
Husain, S1
Hussain, R1
Bhat, AD1
Keasler, PM1
Kolluru, L1
Dombrowski, MM1
Palanisamy, A1
Singh, PM1
Andrade, FO1
Nguyen, NM1
Warri, A2
Hilakivi-Clarke, L2
Antza, C1
Dimou, C1
Doundoulakis, I1
Akrivos, E1
Stabouli, S1
Haidich, AB1
Goulis, DG1
Kotsis, V1
Kantorowska, A1
Heiselman, CJ1
Halpern, TA1
Akerman, MB1
Elsayad, A1
Muscat, JC1
Sicuranza, GB1
Vintzileos, AM1
Heo, HJ1
Chera-Aree, P1
Tengtrakulcharoen, P1
Leetheeragul, J1
Sampaojarean, U1
Surasereewong, S1
Wataganara, T1
Larkin, BP1
Saad, S1
Glastras, SJ1
Nguyen, LT1
Hou, M1
Chen, H1
Wang, R1
Pollock, CA1
Leible, S1
Canals, A1
Walton, R1
Mitelman, G1
Castiglione, A1
Biron, M1
Faundez, R1
Sepulveda, W1
Sharma, KJ2
Amaral, LM1
Wallace, K1
Owens, M1
LaMarca, B1
Sharma, C1
Soni, A1
Gupta, A1
Verma, A1
Verma, S1
Watson, K1
Broscious, R1
Devabhakthuni, S1
Noel, ZR1
Sridharan, K1
Sequeira, RP1
Maaløe, N1
Andersen, CB1
Housseine, N1
Meguid, T1
Bygbjerg, IC1
van Roosmalen, J1
Leavitt, K1
Običan, S1
Yankowitz, J1
Habashi, JP1
MacFarlane, EG1
Bagirzadeh, R1
Bowen, C1
Huso, N1
Chen, Y1
Bedja, D1
Creamer, TJ1
Rykiel, G1
Manning, M1
Huso, D1
Dietz, HC1
Han, LW1
Ryu, RJ1
Cusumano, M1
Easterling, TR2
Phillips, BR1
Risler, LJ1
Shen, DD1
Hebert, MF1
Alexander, JM1
Wilson, KL1
Arulkumaran, N1
Lightstone, L1
Homam, H1
Moukhah, S1
Alizadeh, M1
Gevaert, S1
De Pauw, M1
Tromp, F1
Ascoop, AK1
Roelens, K1
De Backer, J1
Firoz, T1
Magee, LA3
MacDonell, K1
Payne, BA1
Gordon, R1
Vidler, M1
von Dadelszen, P2
Gangooly, S1
Muttukrishna, S1
Jauniaux, E1
Vadhera, RB1
Simon, M1
Morris, R1
Sunesara, I1
Darby, M1
Novotny, S1
Kiprono, L1
Bautista, L1
Sawardecker, S1
Bofill, J1
Anderson, B1
Martin, JN3
Maille, N1
Gokina, N2
Mandalà, M3
Colton, I1
Osol, G3
Garg, D1
Rahaman, B1
Stein, EG1
Dickman, E1
Olson-Chen, C1
Seligman, NS1
Abreo, A1
Greene, N2
Melsop, K1
Peterson, N1
Shields, LE1
Main, EK1
Rodriguez, M1
Aghajanian, P1
Bouker, KB1
Zhang, X1
Cook, KL1
Jin, L1
Zwart, A1
Nguyen, N1
Hu, R1
Cruz, MI1
de Assis, S1
Wang, X1
Xuan, J1
Wang, Y1
Wehrenberg, B1
Clarke, R1
Barton, JR1
Sibai, BM5
Kawasaki, S1
Kako, K1
Nagashima, Y1
Kanou, A1
Ishida, J1
Fukamizu, A1
Yancey, LM1
Withers, E1
Bakes, K1
Abbott, J1
Machaalani, R1
Makris, A3
Thornton, C2
Hennessy, A3
Thadani, U1
Jacob, RG1
McCoy, S1
Baldwin, K1
Barron, C2
Ishii, M1
Hattori, A1
Numaguchi, Y1
Ma, X1
Nagasaka, T1
Tsujimoto, M1
Murohara, T1
Kobayashi, H1
Mizutani, S1
Kawamura, M1
Itoh, H1
Yura, S1
Mogami, H1
Fujii, T1
Kanayama, N1
Konishi, I1
Baggio, MR1
Martins, WP1
Calderon, AC1
Berezowski, AT1
Marcolin, AC1
Duarte, G1
Cavalli, RC1
Archer, TL1
Conrad, BE1
Rezaei, Z1
Sharbaf, FR1
Pourmojieb, M1
Youefzadeh-Fard, Y1
Motevalian, M1
Khazaeipour, Z1
Esmaeili, S1
Teran, E1
Briones, F1
Nicolalde, V1
Vivero, S1
Chedraui, P1
Pérez-López, FR1
Sangalli, JR1
De Bem, TH1
Perecin, F1
Chiaratti, MR1
Oliveira, Lde J1
de Araújo, RR1
Valim Pimentel, JR1
Smith, LC1
Meirelles, FV1
Liu, QQ1
Yu, YH1
Gong, SP1
Huang, LP1
Choi, JH1
Yoo, KH1
Cheon, HW1
Kim, KB1
Hong, YS1
Lee, JW1
Kim, SK1
Kim, CH1
Sato, N1
Tanaka, KA1
Szlam, F1
Tsuda, A1
Arias, ME1
Levy, JH1
Adams, KM1
Mandel, LS1
Guthrie, KA1
Atkinson, MW1
Sameshima, H1
Kawagoe, Y1
Ikenoue, T1
Sakamoto, H1
ASSALI, NS6
SUYEMOTO, R2
COHEN, BM1
KAPLAN, S1
OIGHENSTEIN, S1
KAPLAN, SA1
McCALL, ML2
RENZI, AA1
GAUNT, R1
GIAROLA, A1
SHERMAN, RL2
RIVA, HL2
FINNERTY, FA1
JORDAN, WK1
DRAPS, H1
CHAPMAN, ER1
STROZIER, WE1
MAGEE, RA1
DRAPS, MH1
PICKHARDT, WL1
HOLZWORTH, RH1
QUINZANI, F1
TALAS, M1
HECZKO, P1
VASKOVA, M1
FARRIS, C1
KRUPP, PJ1
BRYANT, RD1
SUNDFOR, H1
JOHNSON, GT1
THOMPSON, RB1
LINDHOLM, T1
GRODY, MH1
SATTENSPIEL, E1
SMITH, GC1
BECK, L1
MOLUMPHY, PE1
GARCIA, R1
HOPFGARTNER, A1
TACCHI, D1
SPIELMANN, W1
KAHN, K1
KAMAL, I1
DAVIS, CD1
GOLDBERG, LC1
NEWTON, M1
KROGSGAARD, AR1
ALEXANDER, JA3
ROGERS, SF3
JACOBS, WM2
WILLS, SH2
URANGAIMAZ, FA2
TONNELIER, E1
KLAUER, D1
CHEKERDEMIAN, M1
SARLES, HE1
HERRING, ME1
WATSON, TF1
GREGORY, RL1
REMMERS, AR1
BELONOSCHKIN, B1
MANCINI, RT1
GAUTIERI, RF3
MACLAVERTY, MP1
PAVLIC, RS1
SMITH, CJ1
ASHE, JR1
THOMAS, WL1
Thigpen, BD1
Rose, CH1
Cushman, J1
Moore, A1
May, WL1
Cham, C1
Waterman, EJ1
Ohlsson, A1
Winston, AW1
Norman, D1
Houlihan, DD1
Dennedy, MC1
Ravikumar, N1
Morrison, JJ1
Heazell, AE1
Mahomoud, S1
Pirie, AM1
Xu, B1
Ogle, R1
Horvath, JS3
Thornton, CE1
Ogle, RF1
Henderson-Smart, DJ1
Gillin, AG1
Child, A2
Olatunji, AO1
Sule-Odu, AO1
Volach, V1
Elami, A1
Gilon, D1
Pollak, A1
Ginosar, Y1
Ezra, Y1
Omu, AE2
Al-Harmi, J1
Vedi, HL1
Mlechkova, L1
Sayed, AF1
Al-Ragum, NS1
Kreisberg, RA1
Morgan, J1
Carmichael, E1
Pittman, J1
Chesley, LC1
Richter, R1
Sandström, B6
Hayashi, RH1
Liedholm, H2
Melander, A2
Lubbe, WF1
Fujita, S1
Yamauchi, C1
Prichard, BN1
Liu, TL1
Holzgreve, H1
Knuppel, RA1
Montenegro, R1
Tullio, D1
Redman, CW4
Ram, CV1
Petty, R1
Medley, DR1
Skret, A2
Kuźniar, J2
Piela, A2
Zaczek, T2
Szmigiel, Z2
Hankins, GD1
Wendel, GD1
Cunningham, FG4
Leveno, KJ1
Lindeberg, S3
Lundborg, P2
Regårdh, CG2
Lunell, NO2
Lewander, R1
Nylund, L2
Sarby, B1
Thornström, S1
Walker, JJ2
Greer, I1
Calder, AA1
Hod, M2
Friedman, S3
Theodor, E1
Ovadia, J4
Rocchi, G1
Pritchard, JA5
Pritchard, SA2
Liebowitz, HA1
Hall, PE1
Weiner, CP2
Gelfan, R1
Socol, ML1
Montminy, M1
Teres, D1
Drayer, JI1
Weber, MA1
Berkowitz, RL2
McCubbin, JH1
Anderson, GD3
Dilts, PV1
Karasawa, T1
Hayano, Y1
Imai, N1
Vink, GJ2
Moodley, J5
Garden, A1
Davey, DA2
Dommisse, J2
Wåhlin-Boll, E1
Hanson, A1
Ingemarsson, I1
Davey, M1
Soutter, P1
Welt, SI1
Dorminy, JH1
Jelovsek, FR1
Crenshaw, MC1
Gall, SA1
Reeves, JT1
Bott-Kanner, G3
Schweitzer, A2
Reisner, SH1
Joel-Cohen, SJ1
Rosenfeld, JB2
Philpott, RH2
Widerlöv, E1
Karlman, I1
Storsäter, J1
Lamming, GD1
Broughton Pipkin, F1
Symonds, EM1
Iams, JD1
Semchyshyn, S1
O'Shaughnessy, R1
Moynihan, V1
Zuspan, FP1
Rubin, LJ1
Peter, RH1
Sato, K1
Kojima, M1
Dohi, Y1
Yeowell, HN1
Marshall, MK1
Walker, LC1
Ha, V1
Pinnell, SR1
Leitch, IM1
Read, MA1
Boura, AL1
Walters, WA2
Gudmundsson, S1
Gennser, G1
Marsal, K1
Duley, L2
Rossouw, HJ1
Howarth, G1
Odendaal, HJ1
Cervar, M1
Kainer, F1
Desoye, G1
Levin, AC1
Doering, PL1
Hatton, RC1
Hsueh, WA1
Belfort, MA1
Saade, GR1
Suresh, M1
Johnson, D1
Vedernikov, YP1
Paran, E2
Holzberg, G1
Mazor, M1
Zmora, E2
Insler, V1
Bowlby, H1
Paterson-Brown, S1
Robson, SC1
Redfern, N1
Walkinshaw, SA1
de Swiet, M1
Gant, NF3
Pryde, PG1
Abel, EL1
Hannigan, J1
Evans, MI1
Cotton, DB4
Hjertberg, R2
Faxelius, G2
Belfrage, P1
Pue, AF1
Walss Rodriguez, RJ2
Flores Padilla, LM1
Lagercrantz, H1
López-Jaramillo, P1
Narváez, M1
Calle, A1
Rivera, J1
Jácome, P1
Ruano, C1
Nava, E1
Jegasothy, R1
Paranthaman, S1
Nasu, K1
Yoshimatsu, J1
Anai, T1
Miyakawa, I1
Makhseed, M1
al-Qattan, F1
Suzuki, H1
Kwawukume, EY1
Ghosh, TS1
Curtis, KS1
Cunningham, JT1
Heesch, CM1
Martínez-Abundis, E1
González-Ortiz, M1
Cortés-Llamas, V1
Salazar-Páramo, M1
Magee, KP1
Bawdon, RE1
Edwards, N1
Blyton, CM1
Kesby, GJ1
Wilcox, I1
Sullivan, CE1
El-Dahr, SS1
Harrison-Bernard, LM1
Dipp, S1
Yosipiv, IV1
Meleg-Smith, S1
Bull, SB1
Koren, G1
Logan, A1
Hassan, K1
Weissmam, I1
Osman, S1
Gery, R1
Oettinger, M1
Shasha, SM1
Kristal, B1
Hussein, M1
Mooij, JM1
Roujouleh, H1
Anato, V1
Garmendia, JV1
Bianco, NE1
De Sanctis, JB1
Aali, BS1
Nejad, SS1
Monnier, JC1
Honore, P1
Lanciaux, B1
Boulogne, M1
Madden, JD1
Siiteri, PK1
MacDonald, PC1
Romankiewicz, JA1
Lammintausta, R1
Curet, LB1
Olson, RW1
Becker, CE1
Benowitz, NL1
Arias, F1
Zamora, J1
Henrich, WL1
Cronin, R1
Miller, PD1
Anderson, RJ1
Nochimson, DJ1
Petrie, RH1
Worley, RJ1
Whalley, PJ1
Schoenfeld, A1
Joel-Cohen, J1
Adelman, RD1
Merten, D1
Vogel, J1
Goetzman, BW1
Wennberg, RP1
Armon, PJ1
Hibbard, BM1
Rosen, M1
Kelly, JV1
Ring, G1
Krames, E1
Shnider, SM2
Wallis, KL1
Levinson, G1
Brinkman, CR4
Pascual, AV1
Woods, JR1
Freis, ED1
Ragan, D1
Shvarts, R1
Rettske, U1
Duggan, PM1
McCowan, LM1
Stewart, AW1
Pedron, SL1
Reid, DL1
Barnard, JM1
Henry, JB1
Phernetton, TM1
Rankin, JH1
Baumann, P1
Künzel, W1
Vertommen, JD1
Hughes, SC1
Rosen, MA1
Espinoza, MI1
Messer, CP1
Johnson, JL1
Parer, JT1
Mooij, PN1
Nijhuis, JG1
Jongsma, HW1
Menssen, JJ1
Catanzarite, V1
Quirk, JG1
Aisenbrey, G1
Fairlie, FM1
Villarreal Ordaz, F1
Fenakel, K1
Fenakel, G1
Appelman, Z1
Lurie, S1
Katz, Z1
Shoham, Z2
Phippard, AF1
Fischer, WE1
Child, AG1
Korda, AR1
Henderson-Smart, D2
Duggin, GG2
Tiller, DJ2
Allen, J1
Skajaa, K1
Maigaard, S1
Forman, A1
Kirshon, B2
Wasserstrum, N2
Flowers, D1
Clark, JF1
Westney, LS1
Harper, A1
Murnaghan, GA1
Plouin, PF1
Breart, G1
Llado, J1
Dalle, M1
Keller, ME1
Goujon, H1
Berchel, C1
Derham, RJ2
Robinson, J1
Hawkins, DF1
De Vries, LS1
Aber, VR1
Elder, MG1
Yemini, M1
Dgani, R1
Lancet, M1
Mogilner, BM1
Nissim, F1
Bar-Khayim, Y1
Rossavik, IK1
Willis, RS1
Moise, KJ1
Griffis, KR1
Palmer, SM1
Martin, RW1
Morrison, JC2
Belfort, M1
Uys, P1
Chervenak, FA1
Gallery, ED2
Naden, RP1
Durando, C1
Leidi, L1
Margaria, E1
Medaglia, M1
Gessa, M1
Maina, G1
Rubin, PC1
Widerhorn, J1
Rubin, JN1
Frishman, WH1
Elkayam, U1
Benedetti, TJ1
Schmucker, BC1
Carlson, KL1
Lodeiro, JG1
Feinstein, SJ1
Lodeiro, SB1
Balkovetz, DF1
Tiruppathi, C1
Leibach, FH1
Mahesh, VB1
Ganapathy, V1
Sullivan, JM1
Holm, B1
Mabie, WC1
Gonzalez, AR1
Amon, E1
Brengman, SL1
Burns, MK1
Nelson, SH1
Suresh, MS1
Peters, JM1
Lönnerdal, B1
Keen, CL1
Smeda, JS1
Lee, RM1
Forrest, JB1
Herrig, J1
Wang, J1
Wang, L1
Farley, D1
Van Orden, D1
Chestnut, D1
Hoffmann, P1
Bartels, T1
Heinemann, S1
Beitz, J1
Taube, C1
Ashe, RG1
Richards, AM1
Vasant, RV1
Reti, LL1
Ross, A1
Kloss, M1
Paull, J1
Markman, L1
Spinnato, JA2
Barnea, ER1
Fakih, H1
Oelsner, G1
Walner, S1
DeCherney, AH1
Naftolin, F1
Neri, A1
Nitke, S1
Lachman, E1
Rading, A1
Kehrbein, C1
Benndorf, S1
Steinig, G1
Nahrendorf, W1
Weidler, B1
Suonio, S1
Saarikoski, S1
Tahvanainen, K1
Pääkkönen, A1
Olkkonen, H1
Rosenfeld, J1
Boner, G1
Nissenkorn, A1
Merlob, P1
Reisner, S1
Chopra, A1
Chib, P1
Singh, RP1
Prabhakaran, SN1
Goodlin, RC1
Lipshitz, J1
Ahokas, RA1
Reynolds, SL1
Jouppila, P1
Kirkinen, P1
Koivula, A1
Ylikorkala, O1
Högstedt, S1
Axelsson, O1
Lindmark, G1
Rane, A1
Lindberg, BS1
Ross, MR1
Gyory, AZ1
Franke, G1
Pietsch, P1
Schneider, T1
Siegmund, W1
Grabow, D1
Schütz, H1
Schwartz, ML1
Brenner, W1
Redgrave, JE1
Swartz, SL1
Whitworth, NS1
Bates, GW1
McKay, ML1
Gookin, KS1
Wiser, WL1
Friesen, HG1
Taslimi, M1
Abdella, TN1
Brooks, TF1
Korda, A1
Phippard, A1
Hall, BM1
Gonik, B1
Dorman, KF1
Gimovsky, ML1
Ojeda, A1
Ozaki, R1
Zerne, S1
Kincaid-Smith, P1
Abella, R1
Blondeel, NJ1
Roguska, J1
Walker, C1
Simon, NM1
Del Greco, F1
Ward, CO2
Ladner, C1
Weston, P1
Martin, JD1
Leroux-Robert, C1
Beaufils, M1
Richet, G1
Tischler, E1
Joyce, DN1
Kenyon, VG1
Fernandes, M1
Kim, KE1
Moyer, JH1
Wilber, JA1
Haller, J1
Eklöf-Slangus, S1
Baskett, TF1
Bradford, CR1
Tucker, RM1
Hunt, JC1
Vaidya, RA1
Vaidya, AB1
Van Woert, MH1
Kase, NG1
Harbert, GM1
Cornell, GW1
Thornton, WN1
Graf, H1
Nohira, T1
Hohe, PT1
Cochrane, CR1
Gmelich, JT1
Austin, JA1
Ragni, N1
Cadenelli, GP1
Stone, SR1
Jorring, K1
Ladner, CN1
Weston, PV1
Evans, DA1
Heinrich, F1
Schultis, K1
Flowers, CE1
Harley, JM1
Cretti, A1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The PartoMa Project for Saving Lives at Birth - An Intervention Based Study to Strengthen the Quality of Monitoring, Action and Triage During Labour at an East African Referral Hospital[NCT02318420]3,087 participants (Actual)Interventional2014-10-01Completed
Use of Sildenafil Citrate in Management of Mild Pre-eclampsia: A Randomized Controlled Trial[NCT03262961]Phase 2/Phase 380 participants (Anticipated)Interventional2016-09-15Recruiting
A Comparison of Fetal Hemodynamic Measurements Between Pregnant Women Taking Anti-hypertensive Medication and Controls[NCT00759278]0 participants (Actual)Observational2008-08-31Withdrawn (stopped due to No participants)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

46 reviews available for hydralazine and Pregnancy

ArticleYear
Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials.
    Hypertension in pregnancy, 2022, Volume: 41, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Hypertension, Pr

2022
Hypertensive Crisis in Pregnancy.
    Obstetrics and gynecology clinics of North America, 2022, Volume: 49, Issue:3

    Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Labetalol; Nifedipine; Pregnancy

2022
A review on the clinical pharmacokinetics of hydralazine.
    Expert opinion on drug metabolism & toxicology, 2022, Volume: 18, Issue:10

    Topics: Drug-Related Side Effects and Adverse Reactions; Female; Heart Failure; Humans; Hydralazine; Hyperte

2022
Treatment of acute-onset hypertension in pregnancy: A network meta-analysis of randomized controlled trials comparing anti-hypertensives and route of administration.
    Pregnancy hypertension, 2023, Volume: 34

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydralazine; Hypertension; Infant

2023
The flipside of hydralazine in pregnancy: A systematic review and meta-analysis.
    Pregnancy hypertension, 2020, Volume: 19

    Topics: Antihypertensive Agents; Birth Weight; Female; Heart Rate; Humans; Hydralazine; Hypertension; Hypert

2020
Postpartum Hypertension: Etiology, Diagnosis, and Management.
    Obstetrical & gynecological survey, 2017, Volume: 72, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Disease Management; Female; Humans; Hydralazine; Hypertensi

2017
Pathophysiology and Current Clinical Management of Preeclampsia.
    Current hypertension reports, 2017, Volume: 19, Issue:8

    Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delivery, Obstetric; Endothelium,

2017
Focused Update on Pharmacologic Management of Hypertensive Emergencies.
    Current hypertension reports, 2018, 06-08, Volume: 20, Issue:7

    Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Emergencies; Enalapri

2018
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:9

    Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy

2018
Treatment and Prevention of Hypertensive Disorders During Pregnancy.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Chronic Dis

2019
Hypertensive emergencies of pregnancy.
    Obstetrics and gynecology clinics of North America, 2013, Volume: 40, Issue:1

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Creatine; Diuretics; Emergency Medicine; Female;

2013
Severe pre-eclampsia and hypertensive crises.
    Best practice & research. Clinical obstetrics & gynaecology, 2013, Volume: 27, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Critical Care; Early Dia

2013
Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review.
    BJOG : an international journal of obstetrics and gynaecology, 2014, Volume: 121, Issue:10

    Topics: Administration, Oral; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Pregnancy-

2014
Hypertensive emergencies in pregnancy.
    Clinical obstetrics and gynecology, 2014, Volume: 57, Issue:4

    Topics: Antihypertensive Agents; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hyperten

2014
Hypertensive Emergencies in Pregnancy.
    Critical care clinics, 2016, Volume: 32, Issue:1

    Topics: Antihypertensive Agents; Cesarean Section; Chronic Disease; Congenital Abnormalities; Emergencies; E

2016
Pharmacotherapeutic options for the treatment of preeclampsia.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, Feb-15, Volume: 66, Issue:4

    Topics: Female; Humans; Hydralazine; Magnesium Sulfate; Nicardipine; Nifedipine; Nitroprusside; Pre-Eclampsi

2009
[Clinical efficacy and perinatal outcome of nifedipine for severe preeclampsia: meta-analysis].
    Zhonghua fu chan ke za zhi, 2012, Volume: 47, Issue:8

    Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Infant, Newborn;

2012
Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis.
    BMJ (Clinical research ed.), 2003, Oct-25, Volume: 327, Issue:7421

    Topics: Antihypertensive Agents; Blood Pressure; Bradycardia; Female; Heart Rate, Fetal; Humans; Hydralazine

2003
Pregnancy in Marfan syndrome after aortic root replacement: a case report and review of the literature.
    Congenital heart disease, 2006, Volume: 1, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Aortic Diseases; Aortic Dissection; Blo

2006
The control of hypertension in pregnancy.
    Obstetrics and gynecology annual, 1981, Volume: 10

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsi

1981
Management of the pregnant patient with chronic hypertension.
    Clinical therapeutics, 1983, Volume: 5, Issue:6

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Humans; Hydralaz

1983
Hypertension in pregnancy. Pathophysiology and management.
    Drugs, 1984, Volume: 28, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Clon

1984
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
    Drugs, 1984, Volume: 28 Suppl 2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihyp

1984
Preeclampsia--eclampsia: an overview.
    The Journal of the Florida Medical Association, 1983, Volume: 70, Issue:9

    Topics: Blood Pressure; Eclampsia; Electroencephalography; Female; Hospitalization; Humans; Hydralazine; Inf

1983
[Arterial hypertension in pregnancy. Concise review].
    Minerva medica, 1983, Apr-28, Volume: 74, Issue:18

    Topics: Cesarean Section; Diet, Sodium-Restricted; Female; Humans; Hydralazine; Hypertension; Labor, Induced

1983
The management of hypertension in pregnancy.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1984, Volume: 169

    Topics: Cerebrovascular Circulation; Clinical Trials as Topic; Diazoxide; Diuretics; Female; Humans; Hydrala

1984
Hypertensive crisis.
    Cardiology clinics, 1984, Volume: 2, Issue:2

    Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia

1984
Anti-hypertensive drugs in the pregnant patient.
    Obstetrical & gynecological survey, 1980, Volume: 35, Issue:4

    Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide

1980
Management of preeclampsia and eclampsia.
    Kidney international, 1980, Volume: 18, Issue:2

    Topics: Anticonvulsants; Antihypertensive Agents; Delivery, Obstetric; Diuretics; Eclampsia; Female; Humans;

1980
Treatment of hypertension in pregnancy.
    Kidney international, 1980, Volume: 18, Issue:2

    Topics: Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyldopa; Placenta; Pre-Eclampsia

1980
Use of nifedipine in the hypertensive diseases of pregnancy.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:12

    Topics: Female; Humans; Hydralazine; Hypertension; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnancy Complicat

1994
Management of eclampsia.
    Seminars in perinatology, 1994, Volume: 18, Issue:2

    Topics: Adult; Anticonvulsants; Antihypertensive Agents; Eclampsia; Female; Fetal Diseases; Fetus; Humans; H

1994
[Pregnancy induced hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bed Rest; Contraindications; Fema

1997
The generalizability of trial data; a comparison of beta-blocker trial participants with a prospective cohort of women taking beta-blockers in pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 94, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Cohort Studies; Databases as Topic; Diabetes, Gestational; Femal

2001
The use of antihypertensive drugs in hypertension in pregnancy.
    Clinics in obstetrics and gynaecology, 1977, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretic

1977
Pharmacology and clinical use of drugs in hypertensive emergencies.
    American journal of hospital pharmacy, 1977, Volume: 34, Issue:2

    Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Aorta; Brain Diseases; Cerebral Hemorrhage; Diazox

1977
How to manage hypertensive emergencies and urgencies.
    Geriatrics, 1976, Volume: 31, Issue:1

    Topics: Adult; Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxid

1976
Intracranial pressure and fetal heart rate in a hydrocephalic fetus during labor.
    European journal of obstetrics, gynecology, and reproductive biology, 1992, Jan-31, Volume: 43, Issue:2

    Topics: Adult; Drainage; Female; Heart Rate, Fetal; Humans; Hydralazine; Hydrocephalus; Intracranial Pressur

1992
Severe preeclampsia: is vasodilation therapy with hydralazine dangerous for the preterm fetus?
    American journal of perinatology, 1990, Volume: 7, Issue:3

    Topics: Female; Fetus; Humans; Hydralazine; Hypotension; Pre-Eclampsia; Pregnancy

1990
Hypertension in pregnancy.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Chronic Disease; Clonidine; Diuretics; Female; Humans; Hydrala

1985
Hypertension in pregnant women.
    The Medical journal of Australia, 1985, Jul-08, Volume: 143, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Delivery, Obstetric; Diazoxide; Emergencies; F

1985
Antihypertensive drugs in pregnancy.
    Clinics in perinatology, 1985, Volume: 12, Issue:3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Fetus; Humans; H

1985
Treatment of hypertension in pregnancy.
    Clinics in obstetrics and gynaecology, 1986, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsia; Female; Human

1986
Cardiovascular drugs in pregnancy.
    Cardiology clinics, 1987, Volume: 5, Issue:4

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiovascular Agents; Digoxin; Female; Humans;

1987
Hypertensive emergencies.
    Pennsylvania medicine, 1974, Volume: 77, Issue:7

    Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume

1974
Recent advances in the medical and surgical treatment of hypertension.
    The Medical clinics of North America, 1968, Volume: 52, Issue:5

    Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni

1968

Trials

37 trials available for hydralazine and Pregnancy

ArticleYear
Comparison of intravenous labetalol and hydralazine for severe hypertension in pregnancy in Northeastern Nigeria: A randomized controlled trial.
    Pregnancy hypertension, 2022, Volume: 29

    Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Infant; Infant,

2022
Effectiveness of nifedipine, labetalol, and hydralazine as emergency antihypertension in severe preeclampsia: a randomized control trial.
    F1000Research, 2022, Volume: 11

    Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Labetalol; Nifedipine; Pre-Eclampsia; Pregnanc

2022
Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial.
    American journal of obstetrics and gynecology, 2017, Volume: 217, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Apgar Score; Double-Blind Method; Emergencies; Female; Humans; Hyd

2017
Impedance cardiography assessed treatment of acute severe pregnancy hypertension: a randomized trial.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2016, Volume: 29, Issue:2

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Cardiography, Impedance; Female; Hum

2016
Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial.
    Ultrasound in medicine & biology, 2011, Volume: 37, Issue:1

    Topics: Acute Disease; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Labetalol;

2011
Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy.
    Acta medica Iranica, 2011, Volume: 49, Issue:11

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; H

2011
Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of cloned cattle.
    Cellular reprogramming, 2012, Volume: 14, Issue:3

    Topics: Acetylation; Animals; Azacitidine; Cattle; Cell Nucleus; Cells, Cultured; Chromatin Assembly and Dis

2012
A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2007, Volume: 47, Issue:4

    Topics: Adult; Antihypertensive Agents; Cardiotocography; Cesarean Section; Diazoxide; Female; Humans; Hydra

2007
The management of hypertension in pregnancy.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1984, Volume: 169

    Topics: Cerebrovascular Circulation; Clinical Trials as Topic; Diazoxide; Diuretics; Female; Humans; Hydrala

1984
Treatment of acute pregnancy-related hypertension: labetalol and hydralazine compared.
    Postgraduate medical journal, 1983, Volume: 59 Suppl 3

    Topics: Ethanolamines; Female; Heart Rate; Humans; Hydralazine; Hypertension; Labetalol; Pregnancy; Pregnanc

1983
Intravenous labetalol and intravenous dihydralazine in severe hypertension in pregnancy.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1982, Volume: 1, Issue:2-3

    Topics: Adult; Blood Pressure; Dihydralazine; Eclampsia; Ethanolamines; Female; Fetus; Humans; Hydralazine;

1982
The effects of prophylactic management and therapeutics on hypertensive disease in pregnancy: preliminary studies.
    Obstetrics and gynecology, 1981, Volume: 57, Issue:5

    Topics: Adult; Antihypertensive Agents; Birth Weight; Blood Pressure; Body Weight; Female; Humans; Hydralazi

1981
Comparison of the alpha and beta blocking drug, labetalol, and methyl dopa in the treatment of moderate and severe pregnancy-induced hypertension.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:5

    Topics: Adult; Blood Pressure; Creatinine; Ethanolamines; Female; Fetus; Humans; Hydralazine; Hypertension;

1980
Effects of hydralazine on placental and renal circulation in pre-eclampsia.
    Acta obstetricia et gynecologica Scandinavica, 1995, Volume: 74, Issue:6

    Topics: Adult; Birth Weight; Blood Circulation; Blood Flow Velocity; Blood Pressure; Drug Evaluation; Female

1995
Ketanserin and hydralazine in hypertension in pregnancy--a randomised double-blind trial.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1995, Volume: 85, Issue:6

    Topics: Adolescent; Adult; Blood Pressure; Double-Blind Method; Female; Humans; Hydralazine; Ketanserin; Pre

1995
Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; Drug Therapy, Combination; Female

1995
Comparison of outcome of labetalol or hydralazine therapy during hypertension in pregnancy in very low birth weight infants.
    Acta obstetricia et gynecologica Scandinavica, 1993, Volume: 72, Issue:8

    Topics: Adult; Female; Humans; Hydralazine; Infant, Low Birth Weight; Infant, Newborn; Labetalol; Pre-Eclamp

1993
[Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents].
    Ginecologia y obstetricia de Mexico, 1993, Volume: 61

    Topics: Administration, Sublingual; Antihypertensive Agents; Apgar Score; Drug Evaluation; Eclampsia; Female

1993
Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice.
    The journal of obstetrics and gynaecology research, 1996, Volume: 22, Issue:1

    Topics: Administration, Sublingual; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydra

1996
Effect of antihypertensive therapy in preeclampsia on levels of serum interleukin-4.
    Gynecologic and obstetric investigation, 1996, Volume: 42, Issue:4

    Topics: Adult; Antihypertensive Agents; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydralazine; Infu

1996
Oral nifedipine therapy in the management of severe preeclampsia.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1995, Volume: 49, Issue:3

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Infusions, Intrav

1995
Nifedipine or hydralazine as a first-line agent to control hypertension in severe preeclampsia.
    Acta obstetricia et gynecologica Scandinavica, 2002, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Nifedipine;

2002
The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy.
    International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:12

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Electrolytes; Female; H

1978
Antihypertensive drug effects on placental flow velocity waveforms in pregnant women with severe hypertension.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1992, Volume: 32, Issue:4

    Topics: Arteries; Blood Flow Velocity; Double-Blind Method; Female; Humans; Hydralazine; Hypertension; Nifed

1992
[Management of severe pre-eclampsia in the puerperium. Comparative study of sublingual nifedipine and hydralazine].
    Ginecologia y obstetricia de Mexico, 1991, Volume: 59

    Topics: Administration, Sublingual; Adolescent; Adult; Antihypertensive Agents; Female; Humans; Hydralazine;

1991
Nifedipine in the treatment of severe preeclampsia.
    Obstetrics and gynecology, 1991, Volume: 77, Issue:3

    Topics: Adult; Blood Pressure; Female; Humans; Hydralazine; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnancy

1991
Early blood pressure control improves pregnancy outcome in primigravid women with mild hypertension.
    The Medical journal of Australia, 1991, Mar-18, Volume: 154, Issue:6

    Topics: Adult; Birth Weight; Blood Pressure; Clonidine; Double-Blind Method; Drug Administration Schedule; D

1991
Maternal and fetal haemodynamics in hypertensive pregnancies during maternal treatment with intravenous hydralazine or labetalol.
    British journal of obstetrics and gynaecology, 1991, Volume: 98, Issue:5

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Female; Heart Rate; Heart Rate, Fetal; Hemodynamics; Hum

1991
A randomized comparison of early with conservative use of antihypertensive drugs in the management of pregnancy-induced hypertension.
    British journal of obstetrics and gynaecology, 1990, Volume: 97, Issue:2

    Topics: Adult; Birth Weight; Cesarean Section; Dihydralazine; Double-Blind Method; Drug Therapy, Combination

1990
Utilization of hydralazine or alpha-methyldopa for the management of early puerperal hypertension.
    American journal of perinatology, 1989, Volume: 6, Issue:4

    Topics: Blood Pressure; Fees, Pharmaceutical; Female; Humans; Hydralazine; Hypertension; Magnesium Sulfate;

1989
Haemodynamic changes in gestational proteinuric hypertension: the effects of rapid volume expansion and vasodilator therapy.
    British journal of obstetrics and gynaecology, 1989, Volume: 96, Issue:6

    Topics: Adult; Cardiac Output; Catheterization, Swan-Ganz; Dihydralazine; Female; Fluid Therapy; Hemodynamic

1989
A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy.
    Obstetrics and gynecology, 1987, Volume: 70, Issue:3 Pt 1

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; H

1987
Comparison of labetalol and dihydralazine in hypertensive emergencies of pregnancy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1987, Mar-21, Volume: 71, Issue:6

    Topics: Blood Pressure; Clinical Trials as Topic; Dihydralazine; Female; Heart Rate; Heart Rate, Fetal; Huma

1987
Lumbar epidural analgesia in hypertensive patients during labour.
    European journal of obstetrics, gynecology, and reproductive biology, 1986, Volume: 22, Issue:1-2

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Pressure; Delivery, Obstetric; Female; Humans;

1986
Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol.
    European journal of obstetrics, gynecology, and reproductive biology, 1986, Volume: 22, Issue:4

    Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Pindolo

1986
A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy.
    Acta obstetricia et gynecologica Scandinavica, 1985, Volume: 64, Issue:6

    Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fetus; Gestational Age; Humans;

1985
Antihypertensive treatment in pregnancy: analysis of different responses to oxprenolol and methyldopa.
    British medical journal (Clinical research ed.), 1985, Aug-31, Volume: 291, Issue:6495

    Topics: Adult; Birth Weight; Clinical Trials as Topic; Female; Humans; Hydralazine; Hypertension; Infant, Ne

1985

Other Studies

234 other studies available for hydralazine and Pregnancy

ArticleYear
Race/ethnicity differences in response to acute antihypertensive treatment of peripartum severe hypertension.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:25

    Topics: Antihypertensive Agents; Blood Pressure; Ethnicity; Female; Humans; Hydralazine; Hypertension; Labet

2022
Trends in antihypertensive prescription for pregnant women with hypertension and their peripartum outcomes before and after label and guideline revisions in Japan.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:11

    Topics: Antihypertensive Agents; Cesarean Section; Drug Prescriptions; Female; Humans; Hydralazine; Hyperten

2022
Use of continuous infusion of nicardipine to control persistent postpartum hypertension: A retrospective study.
    Medicine, 2022, Dec-23, Volume: 101, Issue:51

    Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Labetalol; Nicar

2022
Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women.
    African health sciences, 2023, Volume: 23, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Hypotension; Lab

2023
Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy.
    Scientific reports, 2019, 12-30, Volume: 9, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Diet,

2019
Identification of factors associated with delayed treatment of obstetric hypertensive emergencies.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Adult; After-Hours Care; Antihypertensive Agents;

2020
Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women.
    Journal of clinical pharmacology, 2020, Volume: 60, Issue:12

    Topics: Administration, Intravenous; Adult; Antihypertensive Agents; Apgar Score; Asian People; Blood Pressu

2020
Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet.
    PloS one, 2021, Volume: 16, Issue:3

    Topics: Albuminuria; Animals; Biomarkers; Body Weight; Collagen; Diet, High-Fat; DNA Methylation; Female; Fi

2021
First-trimester miscarriage rate decreases with hydralazine therapy in pregnancies with early uterine vascular insufficiency: a cohort study.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:25

    Topics: Abortion, Spontaneous; Cohort Studies; Female; Humans; Hydralazine; Pregnancy; Pregnancy Trimester,

2022
Effect of locally tailored clinical guidelines on intrapartum management of severe hypertensive disorders at Zanzibar's tertiary hospital (the PartoMa study).
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2019, Volume: 144, Issue:1

    Topics: Anticonvulsants; Antihypertensive Agents; Apgar Score; Delivery, Obstetric; Female; Humans; Hydralaz

2019
Oxytocin antagonism prevents pregnancy-associated aortic dissection in a mouse model of Marfan syndrome.
    Science translational medicine, 2019, 05-01, Volume: 11, Issue:490

    Topics: Adrenergic beta-Antagonists; Animals; Aorta; Aortic Dissection; Disease Models, Animal; Female; Hydr

2019
Effect of N-Acetyltransferase 2 Genotype on the Pharmacokinetics of Hydralazine During Pregnancy.
    Journal of clinical pharmacology, 2019, Volume: 59, Issue:12

    Topics: Acetylation; Adult; Antihypertensive Agents; Area Under Curve; Arylamine N-Acetyltransferase; Female

2019
Asymptomatic torsion of a gravid uterus.
    Taiwanese journal of obstetrics & gynecology, 2013, Volume: 52, Issue:4

    Topics: Adult; Antihypertensive Agents; Asymptomatic Diseases; Cesarean Section; Female; Humans; Hydralazine

2013
Treatment of pre-existing cardiomyopathy during pregnancy.
    Acta cardiologica, 2014, Volume: 69, Issue:2

    Topics: Adult; Antihypertensive Agents; Cardiomyopathy, Dilated; Female; Follow-Up Studies; Heart Failure; H

2014
In-vitro study of the effect of anti-hypertensive drugs on placental hormones and angiogenic proteins synthesis in pre-eclampsia.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Activins; Angiogenic Proteins; Antigens, CD; Antihypertensive Agents; Chorionic Gonadotropin; Chorio

2014
Mechanism of hydralazine-induced relaxation in resistance arteries during pregnancy: Hydralazine induces vasodilation via a prostacyclin pathway.
    Vascular pharmacology, 2016, Volume: 78

    Topics: Animals; Antihypertensive Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endot

2016
Late Postpartum Eclampsia with Postpartum Angiopathy: An Uncommon Diagnosis in the Emergency Department.
    The Journal of emergency medicine, 2015, Volume: 49, Issue:6

    Topics: Adult; Anticonvulsants; Antihypertensive Agents; Drug Therapy, Combination; Eclampsia; Emergency Ser

2015
Severe maternal morbidity in a large cohort of women with acute severe intrapartum hypertension.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:1

    Topics: Adult; Antihypertensive Agents; California; Female; Humans; Hydralazine; Hypertension, Pregnancy-Ind

2016
Risks of parenteral antihypertensive therapy for the treatment of severe maternal hypertension are low.
    Hypertension in pregnancy, 2016, Volume: 35, Issue:1

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension, Pregnancy

2016
Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.
    Journal of the National Cancer Institute, 2017, Volume: 109, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Antineoplastic Combined Chemothe

2017
Controversies Regarding Diagnosis and Treatment of Severe Hypertension in Pregnancy.
    Clinical obstetrics and gynecology, 2017, Volume: 60, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Labetalol; Pre-E

2017
Hydralazine is involved in tele-methylhistamine metabolism by inhibiting monoamine oxidase B in pregnancy-associated hypertensive mice.
    Journal of biochemistry, 2017, Feb-01, Volume: 161, Issue:2

    Topics: Amines; Animals; Antihypertensive Agents; Biocatalysis; Chromatography, High Pressure Liquid; Female

2017
Postpartum preeclampsia: emergency department presentation and management.
    The Journal of emergency medicine, 2011, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Antihypertensive Agents; Benzodiazepines; E

2011
Vascular endothelial growth factor receptor 1 (Flt1) and apoptosis in the preeclamptic placenta and effects of in vivo anti-hypertensive exposure.
    Hypertension in pregnancy, 2008, Volume: 27, Issue:4

    Topics: Adult; Antihypertensive Agents; Apoptosis; Case-Control Studies; Clonidine; Female; Fetal Growth Ret

2008
Isosorbide dinitrate/hydralazine: its role in the treatment of heart failure.
    Drugs of today (Barcelona, Spain : 1998), 2008, Volume: 44, Issue:12

    Topics: Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Interactions; D

2008
Inhibition of nitric oxide synthases abrogates pregnancy-induced uterine vascular expansive remodeling.
    Journal of vascular research, 2009, Volume: 46, Issue:5

    Topics: Animals; Arteries; Blood Pressure; Enzyme Inhibitors; Female; Fertility; Hydralazine; Hypertension,

2009
The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs).
    Early human development, 2009, Volume: 85, Issue:9

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compoun

2009
Angiotensin II receptor blocker candesartan cilexetil, but not hydralazine hydrochloride, protects against mouse cardiac enlargement resulting from undernutrition in utero.
    Reproductive sciences (Thousand Oaks, Calif.), 2009, Volume: 16, Issue:10

    Topics: Animals; Benzimidazoles; Biphenyl Compounds; Caloric Restriction; Cardiomegaly; Disease Models, Anim

2009
Effects of pregnancy, hypertension and nitric oxide inhibition on rat uterine artery myogenic reactivity.
    Journal of vascular research, 2010, Volume: 47, Issue:6

    Topics: Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Female; Hydralazine; Hypertensio

2010
Electrical velocimetry follows the hemodynamics of drug therapy and aortocaval compression in preeclampsia.
    International journal of obstetric anesthesia, 2011, Volume: 20, Issue:1

    Topics: Adult; Antihypertensive Agents; Aorta; Blood Pressure; Cardiac Output; Cardiography, Impedance; Fema

2011
Committee Opinion no. 514: emergent therapy for acute-onset, severe hypertension with preeclampsia or eclampsia.
    Obstetrics and gynecology, 2011, Volume: 118, Issue:6

    Topics: Algorithms; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Pregnancy-Induced; L

2011
Effect of intravenous hydralazine infusion on maternal plasma nitric oxide levels in gestations complicated with severe preeclampsia: a pilot study.
    Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:4

    Topics: Adolescent; Adult; Antihypertensive Agents; Birth Weight; Blood Pressure; Female; Humans; Hydralazin

2012
Angiotensin converting enzyme inhibition decreases cell turnover in the neonatal rat heart.
    Pediatric research, 2002, Volume: 52, Issue:3

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihypertensiv

2002
The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Dopamine; Dose-Response Relation

2003
Interleukin-18 in the plasma of women with preeclampsia.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:5

    Topics: Adult; Antihypertensive Agents; Betamethasone; Case-Control Studies; Drug Therapy, Combination; Fema

2003
Continuous systolic blood pressure monitoring by the difference in electrocardiogram and pulse oximetry in near-term, exteriorized goat fetuses.
    Journal of the Society for Gynecologic Investigation, 2003, Volume: 10, Issue:4

    Topics: Animals; Blood Gas Analysis; Blood Pressure Determination; Electrocardiography; Female; Fetal Monito

2003
The place of the hydrazinophthalazine and thiophanium complications of pregnancy.
    American journal of obstetrics and gynecology, 1952, Volume: 64, Issue:5

    Topics: Hydralazine; Hypertension; Pregnancy; Sympatholytics

1952
Fatal reaction to 1-hydrazinophthalazine (apresoline).
    American heart journal, 1953, Volume: 45, Issue:6

    Topics: Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Sympatholytics

1953
Hemodynamic effects of 1-hydrazinophthalazine (apresoline) in human pregnancy: results of intravenous administration.
    The Journal of clinical investigation, 1953, Volume: 32, Issue:10

    Topics: Administration, Intravenous; Female; Hemodynamics; Hydralazine; Pre-Eclampsia; Pregnancy; Sympatholy

1953
Effects of apresoline, veratrum alkaloids, high spinal anesthesia, and arfonad on renal hemodynamics of pregnant patients with toxemia and essential hypertension.
    Surgery, gynecology & obstetrics, 1953, Volume: 97, Issue:4

    Topics: Anesthesia, Spinal; Essential Hypertension; Female; Hemodynamics; Hydralazine; Hypertension; Pre-Ecl

1953
Cerebral circulation and metabolism in toxemia of pregnancy; observations on the effects of veratrum viride and apresoline (1-hydrazinophthalazine).
    American journal of obstetrics and gynecology, 1953, Volume: 66, Issue:5

    Topics: Brain; Cerebrovascular Circulation; Female; Hydralazine; Pre-Eclampsia; Pregnancy; Sympatholytics; V

1953
Apresoline (l-hydrazinophthalazine) in the experimental eclampsia-like syndrome and related aspects of water metabolism.
    The American journal of physiology, 1953, Volume: 175, Issue:2

    Topics: Eclampsia; Edema; Female; Hydralazine; Kidney; Pregnancy; Sympatholytics; Syndrome; Water

1953
[Clinico-experimental research on circulatory action of some hydrazinophthalazine derivatives with hypotensive action].
    Annali di ostetricia e ginecologia, 1953, Volume: 75, Issue:8

    Topics: Antihypertensive Agents; Female; Hydralazine; Hypertension; Hypotension; Pregnancy; Pregnancy Compli

1953
Experience with hydrazinophthalazine in hypertensive states of pregnancy.
    American journal of obstetrics and gynecology, 1954, Volume: 67, Issue:5

    Topics: Female; Hydralazine; Hypertension; Pregnancy; Pregnancy Complications; Sympatholytics

1954
The use of 1-hydrazinophthalazine (apresoline) in the management of hypertension appearing early in pregnancy.
    The American journal of the medical sciences, 1954, Volume: 228, Issue:2

    Topics: Disease Management; Female; Hydralazine; Hypertension; Pregnancy; Pregnancy Complications; Sympathol

1954
Apresoline (hydralazine hydrochloride) and its use in cases of hypertensive pregnancy.
    American journal of obstetrics and gynecology, 1954, Volume: 68, Issue:2

    Topics: Eclampsia; Female; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Sympatholytics

1954
[Trial of hydrazinophthalazine therapy of hypertension in two cases of grave eclampsia].
    Bulletin de la Federation des societes de gynecologie et dobstetrique de langue francaise, 1953, Volume: 5, Issue:5

    Topics: Eclampsia; Female; Hydralazine; Hypertension; Pregnancy; Sympatholytics

1953
The clinical use of apresoline in the toxemias of pregnancy: a preliminary report.
    American journal of obstetrics and gynecology, 1954, Volume: 68, Issue:4

    Topics: Female; Hydralazine; Pre-Eclampsia; Pregnancy; Sympatholytics; Toxemia

1954
[Experimental hydralazine therapy of hypertension in two cases of severe eclampsia].
    Bruxelles medical, 1954, Sep-05, Volume: 34, Issue:36

    Topics: Eclampsia; Female; Hydralazine; Hypertension; Pregnancy; Sympatholytics; Therapies, Investigational

1954
Continuing vasodilator infusion therapy; utilization of a blend of 1-hydrazinophthalazine (apresoline) and cryptenamine (unitensen) in toxemia of pregnancy.
    Obstetrics and gynecology, 1954, Volume: 4, Issue:4

    Topics: Female; Hydralazine; Pre-Eclampsia; Pregnancy; Protoveratrines; Sympatholytics; Vasodilator Agents;

1954
Further experience with apresoline in toxemia and hypertension of pregnancy.
    American journal of obstetrics and gynecology, 1956, Volume: 72, Issue:1

    Topics: Female; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Sepsis; Sympat

1956
[Hydrazinophthalazine compounds in the treatment of hypertension in obstetrics and gynecology].
    Minerva ginecologica, 1956, Mar-15, Volume: 8, Issue:5

    Topics: Female; Gynecology; Humans; Hydralazine; Hypertension; Kidney Diseases; Obstetrics; Pregnancy; Pregn

1956
[Treatment of gestosis by new hypotensive drugs].
    Casopis lekaru ceskych, 1957, Jan-18, Volume: 96, Issue:3

    Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Reserpine; Sympathol

1957
Antihypertension therapy in toxemia of pregnancy; a 30 month progress report.
    American journal of obstetrics and gynecology, 1957, Volume: 74, Issue:5

    Topics: Female; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Research Report; Veratrum Alkal

1957
Hypotensive drugs in the management of toxemia of pregnancy.
    Postgraduate medicine, 1957, Volume: 22, Issue:4

    Topics: Antihypertensive Agents; Disease Management; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy;

1957
[Nepresol therapy of eclampsia & pre-eclampsia].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1957, Nov-01, Volume: 77, Issue:21

    Topics: Eclampsia; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Sympatholytics

1957
A clinical trial of intravenous apresoline in the management of toxaemia of late pregnancy.
    The Journal of obstetrics and gynaecology of the British Empire, 1958, Volume: 65, Issue:3

    Topics: Bacterial Infections; Disease Management; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Sep

1958
[Anuria after or caused by obstetrical collapse treated with a nepresol-hibernalpethidine preparation].
    Svenska lakartidningen, 1958, May-30, Volume: 55, Issue:22

    Topics: Anuria; Chlorpromazine; Female; Humans; Hydralazine; Meperidine; Obstetric Labor Complications; Obst

1958
Antihypertensive drugs in toxemia: a practical integrated plan of management.
    Obstetrics and gynecology, 1959, Volume: 13, Issue:2

    Topics: Antihypertensive Agents; Bacterial Infections; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy

1959
Routine use of intramuscular apresoline for the prevention of eclampsia.
    Obstetrics and gynecology, 1959, Volume: 13, Issue:4

    Topics: Biomedical Research; Eclampsia; Female; Humans; Hydralazine; Injections, Intramuscular; Pregnancy

1959
[Can infant mortality in late pregnancy toxemia be reduced by treatment with hypotensive drugs].
    Geburtshilfe und Frauenheilkunde, 1959, Volume: 19, Issue:5

    Topics: Antihypertensive Agents; Bacterial Infections; Female; Hydralazine; Infant Mortality; Pre-Eclampsia;

1959
Treatment of severe toxemia of pregnancy with intravenous magnesium sulfate and apresoline.
    Obstetrics and gynecology, 1959, Volume: 14, Issue:2

    Topics: Administration, Intravenous; Female; Humans; Hydralazine; Magnesium Sulfate; Pre-Eclampsia; Pregnanc

1959
[On the treatment of pre-eclampsia with Esidrex and Adelphan-Esidrex].
    Wiener medizinische Wochenschrift (1946), 1961, Jun-10, Volume: 111

    Topics: Chlorothiazide; Drug Combinations; Female; Hydralazine; Hydrazines; Hydrochlorothiazide; Pre-Eclamps

1961
Peripheral vascular response to hydralazine in toxemia of pregnancy.
    Obstetrics and gynecology, 1961, Volume: 18

    Topics: Blood Vessels; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy

1961
[On the treatment of eclampsia].
    Zeitschrift fur Geburtshilfe und Gynakologie, 1962, Volume: 159

    Topics: Eclampsia; Female; Hibernation; Humans; Hydralazine; Hypothermia, Induced; Pregnancy; Rauwolfia

1962
PRE-ECLAMPTIC TOXAEMIA OF PREGNANCY AND THE USE OF ANTI-HYPERTENSIVE DRUGS.
    The Journal of the Egyptian Medical Association, 1963, Volume: 46

    Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hydrochlorothiazide; Pre-Eclampsia; Pregnancy;

1963
A SYSTEMATIC APPROACH TO THE THERAPY OF SEVERE PRE-ECLAMPSIA AND ECLAMPSIA.
    Connecticut medicine, 1963, Volume: 27

    Topics: Abortion, Therapeutic; Anesthesia; Anesthesia, Obstetrical; Anticonvulsants; Antihypertensive Agents

1963
A THIRTY YEAR EVALUATION OF LUPUS ERYTHEMATOSUS.
    Medical times, 1964, Volume: 92

    Topics: Adrenal Cortex Hormones; Anticonvulsants; Antitubercular Agents; Appetite Depressants; Chloroquine;

1964
THE CONTINUING PROBLEM OF ECLAMPSIA.
    Surgery, gynecology & obstetrics, 1964, Volume: 118

    Topics: Amobarbital; Antihypertensive Agents; Cesarean Section; Eclampsia; Female; Humans; Hydralazine; Hype

1964
[MEDICAL TREATMENT OF HYPERTENSIVE CRISES].
    Ugeskrift for laeger, 1964, Apr-23, Volume: 126

    Topics: Diuretics; Female; Ganglionic Blockers; Glomerulonephritis; Hexamethonium Compounds; Humans; Hydrala

1964
RAPID STABILIZATION BY HYPOTENSIVE DRUGS FOLLOWED BY EARLY DELIVERY IN ANTEPARTUM ECLAMPSIA TREATMENT.
    American journal of obstetrics and gynecology, 1964, May-01, Volume: 89

    Topics: Adolescent; Antihypertensive Agents; Cesarean Section; Delivery, Obstetric; Eclampsia; Female; Human

1964
[THERAPEUTICS OF ARTERIAL HYPERTENSION IN PREGNANCY].
    Revista de la Asociacion Medica Argentina, 1964, Volume: 78

    Topics: Female; Guanethidine; Hibernation; Humans; Hydralazine; Hypertension; Hypothermia, Induced; Maternal

1964
CESAREAN SECTION IN THE ECLAMPTIC PATIENT ON ANTIHYPERTENSIVE THERAPY: A REVIEW OF FOURTEEN CASES.
    Southern medical journal, 1964, Volume: 57

    Topics: Adolescent; Anesthesia; Antihypertensive Agents; Cesarean Section; Child; Drug Therapy; Eclampsia; F

1964
THE NEPHROTIC SYNDROME DUE TO PRE-ECLAMPTIC NEPHROPATHY; REPORT OF A CASE.
    Annals of internal medicine, 1964, Volume: 61

    Topics: Blood Pressure; Blood Pressure Determination; Drug Therapy; Female; Humans; Hydralazine; Kidney Dise

1964
[TREATMENT OF PREGNANCY TOXICOSIS WITH ADELPHIN-ESIDREX-K].
    Svenska lakartidningen, 1964, Oct-21, Volume: 61

    Topics: Drug Therapy; Female; Hydralazine; Hydrochlorothiazide; Pre-Eclampsia; Pregnancy; Reserpine

1964
EFFECT OF CERTAIN DRUGS ON PERFUSED HUMAN PLACENTA. IV. DETECTION OF SPECIFIC RECEPTOR SITES.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Epinephrine; Female; Histamine; Humans; Hydralazine; Norepinephrine; Perfusion; Pharmacology; Phento

1964
PROGRAM FOR TOXEMIA CONTROL: STUDY OF 551 CASES.
    American journal of obstetrics and gynecology, 1965, May-01, Volume: 92

    Topics: Anticonvulsants; Delivery, Obstetric; Drug Therapy; Eclampsia; Female; Humans; Hydralazine; Pre-Ecla

1965
Hexamethonium chloride and apresoline in toxemia of pregnancy; a preliminary report.
    Obstetrics and gynecology, 1955, Volume: 5, Issue:3

    Topics: Female; Hexamethonium; Hydralazine; Muscle Relaxants, Central; Pre-Eclampsia; Pregnancy; Sympatholyt

1955
Maternal benefit of high-dose intravenous corticosteroid therapy for HELLP syndrome.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:3

    Topics: Adolescent; Adult; Alanine Transaminase; Antihypertensive Agents; Aspartate Aminotransferases; Betam

2003
Late postpartum eclampsia coincident with postdural puncture headache: a case report.
    AANA journal, 2003, Volume: 71, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anticonvulsants; Antihypertensive Agents; Bloo

2003
Anti-hypertensive therapy and the feto-placental circulation: effects on umbilical artery resistance.
    Journal of perinatal medicine, 2004, Volume: 32, Issue:4

    Topics: Adult; Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Fetus; Humans; Hydralazine

2004
The treatment of severe hypertension in pregnancy: a review of current practice and knowledge in West-Midlands maternity units.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2004, Volume: 24, Issue:8

    Topics: Antihypertensive Agents; Female; Hospital Units; Humans; Hydralazine; Hypertension, Pregnancy-Induce

2004
Antihypertensive drugs clonidine, diazoxide, hydralazine and furosemide regulate the production of cytokines by placentas and peripheral blood mononuclear cells in normal pregnancy.
    Journal of hypertension, 2006, Volume: 24, Issue:5

    Topics: Antihypertensive Agents; Cell Culture Techniques; Cells, Cultured; Clonidine; Culture Media, Conditi

2006
Presentation and outcome of eclampsia at a Nigerian university hospital.
    Nigerian journal of clinical practice, 2007, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Diazepam; Eclampsia; Female; Hospitals, University; Humans; Hydralazine; Incidenc

2007
Magnesium sulphate therapy in women with pre-eclampsia and eclampsia in Kuwait.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2008, Volume: 17, Issue:3

    Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Eclampsia; Fema

2008
Medical grand rounds from the University of Alabama Medical Center.
    Southern medical journal, 1967, Volume: 60, Issue:6

    Topics: Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics

1967
[Antihypertensive therapy in pregnancy].
    Der Gynakologe, 1982, Volume: 15, Issue:3

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Clonidine; Female; Humans; Hydralazine; Hydro

1982
Adrenergic beta-receptor blockers in hypertension of pregnancy.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1982, Volume: 1, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Birth Weight; Blood Pressure; Delivery, Obstetric; F

1982
Drug selection in the treatment of pregnancy hypertension. A survey.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Adrenal Glands; Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Card

1984
Clinical trials of adrenergic antagonists in pregnancy hypertension.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Apgar Score; Birth Weight; Female; Fetal Growt

1984
[Influence of blood pressure control on delivery in pregnant rats in a warm environment].
    Jikken dobutsu. Experimental animals, 1984, Volume: 33, Issue:3

    Topics: Animals; Blood Pressure; Etilefrine; Female; Hot Temperature; Hydralazine; Labor, Obstetric; Pregnan

1984
Therapeutic regime on pregnancy induced hypertension.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1982, Volume: 1, Issue:4

    Topics: Dextrans; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydralazine; Hypertension; I

1982
[Forum on hypertension. Part 8. Hypertension management in pregnancy].
    MMW, Munchener medizinische Wochenschrift, 1981, Jun-12, Volume: 123, Issue:24

    Topics: Antihypertensive Agents; Dihydralazine; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyl

1981
Cutaneous manifestations of hydrallazine toxicity.
    British medical journal, 1980, Feb-16, Volume: 280, Issue:6212

    Topics: Adult; Drug Eruptions; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Pregnancy; Pregna

1980
[Hemodynamic response to hydralazine in pregnant women with hypertension].
    Ginekologia polska, 1984, Volume: 55, Issue:3

    Topics: Female; Hemodynamics; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complic

1984
Longitudinal evaluation of hemodynamic changes in eclampsia.
    American journal of obstetrics and gynecology, 1984, Nov-01, Volume: 150, Issue:5 Pt 1

    Topics: Adolescent; Adult; Cardiac Output; Delivery, Obstetric; Diuresis; Eclampsia; Female; Fluid Therapy;

1984
Disposition of the adrenergic blocker metoprolol in the late-pregnant woman, the amniotic fluid, the cord blood and the neonate.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Amniotic Fluid; Drug Therapy, Combination; Female; Fetal Blood; Humans; Hydralazine; Hypertension; I

1984
Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy.
    Gynecologic and obstetric investigation, 1983, Volume: 16, Issue:5

    Topics: Blood Pressure; Dihydralazine; Female; Heart Rate; Humans; Hydralazine; Hypertension; Placenta; Pre-

1983
[Acute liver disease during treatment of severe preeclampsia].
    Harefuah, 1983, May-01, Volume: 104, Issue:9

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Hydralazine; Liver Dis

1983
[Eclampsia: critical considerations on its therapy].
    La Clinica terapeutica, 1983, May-15, Volume: 105, Issue:3

    Topics: Anesthesia, Epidural; Benzothiadiazines; Diuresis; Eclampsia; Female; Humans; Hydralazine; Magnesium

1983
The Parkland Memorial Hospital protocol for treatment of eclampsia: evaluation of 245 cases.
    American journal of obstetrics and gynecology, 1984, Apr-01, Volume: 148, Issue:7

    Topics: Analgesics; Anesthetics; Delivery, Obstetric; Eclampsia; Female; Fetal Death; Fluid Therapy; Humans;

1984
Cortical blindness as a complication of eclampsia.
    Annals of emergency medicine, 1984, Volume: 13, Issue:5

    Topics: Adult; Blindness; Eclampsia; Female; Humans; Hydralazine; Hypertension; Labor, Induced; Oxytocin; Pr

1984
Intrapartum treatment of preeclamptic hypertension by ketanserin--a serotonin receptor antagonist.
    American journal of obstetrics and gynecology, 1984, Jul-01, Volume: 149, Issue:5

    Topics: Adult; Antihypertensive Agents; Delivery, Obstetric; Female; Humans; Hydralazine; Hypertension; Infa

1984
Shock after phenothiazine administration in a pregnant patient with a pheochromocytoma. A case report and literature review.
    The Journal of reproductive medicine, 1983, Volume: 28, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Diagnosis, Differential; Female; Humans; Hydralazine; Hypertension;

1983
Antihypertensive therapy during pregnancy.
    Comprehensive therapy, 1983, Volume: 9, Issue:3

    Topics: Antihypertensive Agents; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyldopa; Pregnancy

1983
Severe consequence of hypertension in pregnancy.
    American journal of obstetrics and gynecology, 1983, Jan-01, Volume: 145, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pr

1983
Eclampsia: treatment and referral.
    Southern medical journal, 1982, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Delivery, Obstetric; Eclampsia; Female; Humans; Hydralazine; Infant Mortality; In

1982
[Significance & treatment of abnormal blood viscosities in pre-eclamptic patients (author's transl)].
    Nihon Sanka Fujinka Gakkai zasshi, 1982, Volume: 34, Issue:5

    Topics: Adenosine Triphosphate; Adult; Blood Viscosity; Blood Volume Determination; Erythrocyte Count; Femal

1982
The effect of low-dose dihydrallazine on the fetus in the emergency treatment of hypertension in pregnancy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Sep-25, Volume: 62, Issue:14

    Topics: Blood Pressure; Depression, Chemical; Dihydralazine; Female; Fetal Growth Retardation; Fetal Heart;

1982
Transplacental passage and breast milk concentrations of hydralazine.
    European journal of clinical pharmacology, 1982, Volume: 21, Issue:5

    Topics: Adult; Breast Feeding; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Maternal-Fetal Ex

1982
Adverse effects of a combination of diazoxide and hydrallazine therapy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Mar-28, Volume: 59, Issue:14

    Topics: Adolescent; Adult; Blood Pressure; Diazoxide; Drug Interactions; Drug Therapy, Combination; Female;

1981
Preeclampsia and eclampsia.
    The Western journal of medicine, 1981, Volume: 135, Issue:1

    Topics: Adult; Diazoxide; Eclampsia; Female; Humans; Hydralazine; Magnesium Sulfate; Pre-Eclampsia; Pregnanc

1981
Hope in primary pulmonary hypertension.
    The New England journal of medicine, 1980, Jan-10, Volume: 302, Issue:2

    Topics: Child; Diazoxide; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Pregnancy; Tim

1980
Propranolol and hydrallazine in the management of essential hypertension in pregnancy.
    British journal of obstetrics and gynaecology, 1980, Volume: 87, Issue:2

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Hypoglycemia; Infant, N

1980
Effect of dihydralazine on the fetus in the treatment of maternal hypertension.
    Obstetrics and gynecology, 1980, Volume: 55, Issue:4

    Topics: Birth Weight; Dihydralazine; Female; Fetal Death; Fetal Growth Retardation; Fetal Heart; Fetal Monit

1980
Hydralazine-induced neonatal thrombocytopenia.
    The New England journal of medicine, 1980, Nov-20, Volume: 303, Issue:21

    Topics: Adult; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Infant, Newborn, Diseases; Pre-Ec

1980
Blood pressure response in hypertensive pregnancies treated with cortisol.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:5

    Topics: Adolescent; Adult; Blood Pressure; Drug Therapy, Combination; Ethanol; Female; Humans; Hydralazine;

1980
Primary pulmonary hypertension: new approaches to therapy.
    American heart journal, 1980, Volume: 100, Issue:5

    Topics: Diazoxide; Female; Humans; Hydralazine; Hypertension, Pulmonary; Phentolamine; Pregnancy

1980
Depressed sodium-calcium exchange in human umbilical arteries from women with preeclampsia.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:2

    Topics: Adult; Blood Pressure; Calcium; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Sodium; Umbil

1995
Regulation of lysyl oxidase mRNA in dermal fibroblasts from normal donors and patients with inherited connective tissue disorders.
    Archives of biochemistry and biophysics, 1994, Volume: 308, Issue:1

    Topics: Aminopropionitrile; Ascorbic Acid; Bleomycin; Cell Line; Collagen; Connective Tissue Diseases; DNA P

1994
Effect of inhibition of nitric oxide synthase and guanylate cyclase on hydralazine-induced vasodilatation of the human fetal placental circulation.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Amino Acid Oxidoreductases; Aminoquinolines; Arginine; Blood Pressure; Dose-Respo

1994
Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia.
    British journal of obstetrics and gynaecology, 1995, Volume: 102, Issue:7

    Topics: Female; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Randomized Controlled Trials as

1995
Pre-eclampsia and gestational age differently alter binding of endothelin-1 to placental and trophoblast membrane preparations.
    Molecular and cellular endocrinology, 1995, Apr-28, Volume: 110, Issue:1-2

    Topics: Adult; Cell Membrane; Endothelins; Female; Humans; Hydralazine; Placenta; Pre-Eclampsia; Pregnancy;

1995
Pre-eclampsia and hypertension in pregnancy.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Antihypertensive Agents; Contraindications; Female; Guidelines as Topic; Hospitalization; Humans; Hy

1994
Human umbilical vessels: responses to agents frequently used in obstetric patients.
    American journal of obstetrics and gynecology, 1995, Volume: 172, Issue:5

    Topics: Analysis of Variance; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hydralazine; In Vi

1995
Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia.
    British journal of obstetrics and gynaecology, 1995, Volume: 102, Issue:1

    Topics: Female; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy

1995
Hydralazine injection still available.
    American journal of hospital pharmacy, 1994, Dec-15, Volume: 51, Issue:24

    Topics: Female; Humans; Hydralazine; Injections, Intravenous; Pre-Eclampsia; Pregnancy; United States

1994
Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia.
    British journal of obstetrics and gynaecology, 1994, Volume: 101, Issue:5

    Topics: Adult; Blood Pressure; Clinical Protocols; Female; Gestational Age; Humans; Hydralazine; Hydrogen-Io

1994
Effects of hydralazine on pregnant rats and their fetuses.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:4

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Birth Weight; Dose-Response Relationship

1993
Periarterial lidocaine/hydralazine aids arterial catheter insertion in patients with preeclampsia.
    Anesthesiology, 1993, Volume: 79, Issue:2

    Topics: Arteries; Catheterization, Peripheral; Female; Humans; Hydralazine; Lidocaine; Pre-Eclampsia; Pregna

1993
Neonatal adaptation in hypertensive pregnancy--a study of labetalol vs hydralazine treatment.
    Journal of perinatal medicine, 1993, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Female; Fetal Hypoxia; Hemodynamics; Humans; Hydralazine; Infant, Newborn; Labeta

1993
Cyclic guanosine 3',5' monophosphate concentrations in pre-eclampsia: effects of hydralazine.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:1

    Topics: Adult; Arginine; Birth Weight; Blood Pressure; Cyclic GMP; Female; Humans; Hydralazine; Nitric Oxide

1996
Low-dose dopamine in treating acute renal failure caused by preeclampsia.
    Gynecologic and obstetric investigation, 1996, Volume: 42, Issue:2

    Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Blood Urea Nitrogen; Cesarean Section; Creatini

1996
Fos expression in brain stem nuclei of pregnant rats after hydralazine-induced hypotension.
    The American journal of physiology, 1999, Volume: 277, Issue:2

    Topics: Animals; Antihypertensive Agents; Brain Stem; Cerebral Ventricles; Female; Hydralazine; Hypotension;

1999
Anticardiolipin antibodies and the severity of preeclampsia-eclampsia.
    Gynecologic and obstetric investigation, 1999, Volume: 48, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Antibodies, Anticardiolipin; Antihypertensive Agents; Cross-Sectiona

1999
Ex vivo human placental transfer and the vasoactive properties of hydralazine.
    American journal of obstetrics and gynecology, 2000, Volume: 182, Issue:1 Pt 1

    Topics: Chromatography, High Pressure Liquid; Female; Fetal Blood; Humans; Hydralazine; In Vitro Techniques;

2000
Pre-eclampsia is associated with marked alterations in sleep architecture.
    Sleep, 2000, Aug-01, Volume: 23, Issue:5

    Topics: Adult; Antihypertensive Agents; Clonidine; Electroencephalography; Electrooculography; Female; Human

2000
Bradykinin B2 null mice are prone to renal dysplasia: gene-environment interactions in kidney development.
    Physiological genomics, 2000, Sep-08, Volume: 3, Issue:3

    Topics: Angiotensinogen; Animals; Animals, Newborn; Antihypertensive Agents; Aquaporin 2; Aquaporin 6; Aquap

2000
Successful pregnancy in a patient with polycystic kidney disease and advanced renal failure without prophylactic dialysis.
    Nephron, 2001, Volume: 87, Issue:1

    Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Rena

2001
Factor analysis, including antihypertensive medication, of the outcome of pregnancy in pregnancy-associated hypertension.
    Kidney & blood pressure research, 2001, Volume: 24, Issue:2

    Topics: Antihypertensive Agents; Apgar Score; Cesarean Section; Comorbidity; Disease Susceptibility; Female;

2001
Antihypertensive treatment decreased serum leptin levels in severe preeclampsia during pregnancy.
    Annals of nutrition & metabolism, 2001, Volume: 45, Issue:5

    Topics: Adult; Antihypertensive Agents; Body Mass Index; Enzyme-Linked Immunosorbent Assay; Female; Gestatio

2001
[Value of hydralazine-beta blockader association in hypertension of pregnancy].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1978, Volume: 23, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female; Fetus; Humans; Hydralazine; H

1978
Review: the significance and management of raised blood pressure in pregnancy.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1979, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Chlormethiazole; Clonidine; Diazepam; D

1979
The metabolic clearance rate of dehydroisoandrosterone sulfate. IV. Acute effects of induced hypertension, hypotension, and naturesis in normal and hypertensive pregnancies.
    American journal of obstetrics and gynecology, 1976, Jan-15, Volume: 124, Issue:2

    Topics: Adult; Angiotensin II; Blood Pressure; Dehydroepiandrosterone; Female; Furosemide; Humans; Hydralazi

1976
Evaluation of a program of bed rest in the treatment of chronic hypertension in pregnancy.
    Obstetrics and gynecology, 1979, Volume: 53, Issue:3

    Topics: Bed Rest; Birth Weight; Chronic Disease; Female; Fetal Death; Humans; Hydralazine; Hypertension; Inf

1979
Hypertensive emergencies.
    The Medical clinics of North America, 1979, Volume: 63, Issue:1

    Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases

1979
Antihypertensive treatment and pregnancy outcome in patients with mild chronic hypertension.
    Obstetrics and gynecology, 1979, Volume: 53, Issue:4

    Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Fetal Growth Retardation; Fetus; Growth; Hu

1979
Hypotensive sequelae of diazoxide and hydralazine therapy.
    JAMA, 1977, Jan-17, Volume: 237, Issue:3

    Topics: Adult; Diazoxide; Drug Synergism; Female; Humans; Hydralazine; Hypotension; Male; Middle Aged; Pregn

1977
Glucocorticoid therapy for the induction of pulmonary maturity in severely hypertensive gravid women.
    American journal of obstetrics and gynecology, 1979, Feb-15, Volume: 133, Issue:4

    Topics: Betamethasone; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Labor, Induced; Pre-Eclam

1979
Clinical management of pregnancy-induced hypertension.
    Clinical obstetrics and gynecology, 1978, Volume: 21, Issue:2

    Topics: Age Factors; Ambulatory Care; Delivery, Obstetric; Female; Gestational Age; Hospitalization; Humans;

1978
Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report.
    Israel journal of medical sciences, 1978, Volume: 14, Issue:4

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Pregnancy; Pregnancy Co

1978
Nonsurgical management of renovascular hypertension in the neonate.
    Pediatrics, 1978, Volume: 62, Issue:1

    Topics: Adult; Antihypertensive Agents; Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertension, Ren

1978
Pre-eclampsia and eclampsia.
    Tropical doctor, 1978, Volume: 8, Issue:4

    Topics: Anesthesia, Obstetrical; Bed Rest; Cesarean Section; Delivery, Obstetric; Eclampsia; Female; Humans;

1978
Management of severe preeclampsia and eclampsia.
    Seminars in perinatology, 1978, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Delivery, Obstetric; Eclampsia; Female; Humans; Hydralazine; Magnesium Sulfate; P

1978
Antihypertensive treatment with the adrenergic beta-receptor blocker metoprolol during pregnancy.
    Gynecologic investigation, 1978, Volume: 9, Issue:4

    Topics: Apgar Score; Drug Evaluation; Drug Therapy, Combination; Female; Fetal Growth Retardation; Fetus; Hu

1978
The management of severe pre-eclampsia and eclampsia.
    British journal of anaesthesia, 1977, Volume: 49, Issue:1

    Topics: Chlormethiazole; Delivery, Obstetric; Diazepam; Diuretics; Eclampsia; Female; Humans; Hydralazine; H

1977
Drugs used in the management of toxemia of pregnancy.
    Clinical obstetrics and gynecology, 1977, Volume: 20, Issue:2

    Topics: Anticonvulsants; Antihypertensive Agents; Barbiturates; Benzothiadiazines; Blood Volume; Diazepam; D

1977
Comparison of nitroprusside and hydralazine in hypertensive pregnant ewes.
    Obstetrics and gynecology, 1977, Volume: 50, Issue:5

    Topics: Animals; Cardiac Output; Female; Ferricyanides; Heart Rate; Hydralazine; Hypertension; Nitroprusside

1977
Management of eclampsia.
    British medical journal, 1976, Jul-24, Volume: 2, Issue:6029

    Topics: Adult; Chlormethiazole; Clonidine; Eclampsia; Female; Humans; Hydralazine; Pregnancy

1976
Uteroplacental hemodynamic response to antihypertensive drugs in hypertensive pregnant sheep.
    Perspectives in nephrology and hypertension, 1976, Volume: 5

    Topics: Animals; Blood Pressure; Female; Heart Rate; Hydralazine; Hypertension, Renal; Placenta; Pregnancy;

1976
Standardized treatment of 154 consecutive cases of eclampsia.
    American journal of obstetrics and gynecology, 1975, Nov-01, Volume: 123, Issue:5

    Topics: Abruptio Placentae; Anesthesia; Bradycardia; Delivery, Obstetric; Diuretics; Eclampsia; Female; Feta

1975
The treatment of gestational hypertension.
    The Journal of reproductive medicine, 1975, Volume: 15, Issue:5

    Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype

1975
Effect of treatment on longevity in spontaneously hypertensive rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 150, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Chlorothiazide; Female; Hydralazine; Hypertension; Longevity;

1975
[Reduction of the arterial pressure with the help of dihydralazin in late toxemia of pregnancy].
    Akusherstvo i ginekologiia, 1975, Issue:11

    Topics: Blood Pressure; Dihydralazine; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy

1975
Differential effects of intravenous hydralazine on myoendometrial and placental blood flow in hypertensive pregnant ewes.
    American journal of obstetrics and gynecology, 1992, Volume: 167, Issue:6

    Topics: Adrenal Glands; Angiotensin II; Animals; Endometrium; Female; Hydralazine; Hypertension; Injections,

1992
[Antepartum CTG: extreme growth retardation and choice of delivery time].
    Der Gynakologe, 1992, Volume: 25, Issue:1

    Topics: Adult; Cardiotocography; Delivery, Obstetric; Female; Fetal Growth Retardation; Gestational Age; Hum

1992
Hydralazine does not restore uterine blood flow during cocaine-induced hypertension in the pregnant ewe.
    Anesthesiology, 1992, Volume: 76, Issue:4

    Topics: Animals; Blood Pressure; Catecholamines; Cocaine; Female; Fetus; Heart Rate; Hydralazine; Hypertensi

1992
How do perinatologists manage preeclampsia?
    American journal of perinatology, 1991, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure Determination; Data Collection; Delivery, Obstetr

1991
Maternal and fetal haemodynamics in hypertensive pregnancies during maternal treatment with intravenous hydralazine or labetalol.
    British journal of obstetrics and gynaecology, 1991, Volume: 98, Issue:11

    Topics: Female; Heart Rate, Fetal; Hemodynamics; Humans; Hydralazine; Hypertension; Labetalol; Pregnancy; Pr

1991
Effects of vasodilators on isolated human uteroplacental arteries.
    Obstetrics and gynecology, 1991, Volume: 77, Issue:5

    Topics: Angiotensin II; Arteries; Chorionic Villi; Dinoprost; Female; Humans; Hydralazine; Labetalol; Nitren

1991
Should continuous hydralazine infusions be utilized in severe pregnancy-induced hypertension?
    American journal of perinatology, 1991, Volume: 8, Issue:3

    Topics: Apgar Score; Blood Pressure; Female; Fetal Distress; Hemodynamics; Humans; Hydralazine; Infant, Newb

1991
Cocaine intoxication associated with abruptio placentae.
    Journal of the National Medical Association, 1991, Volume: 83, Issue:3

    Topics: Abruptio Placentae; Adult; Cocaine; Female; Humans; Hydralazine; Hypertension; Magnesium Sulfate; Pr

1991
Outcome of pregnancies complicated by severe hypertension and delivered before 34 weeks; stepwise logistic regression analysis of prognostic factors.
    British journal of obstetrics and gynaecology, 1989, Volume: 96, Issue:10

    Topics: Adult; Birth Weight; Cerebral Hemorrhage; Cesarean Section; Female; Fetal Growth Retardation; Gestat

1989
Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report.
    European journal of obstetrics, gynecology, and reproductive biology, 1989, Volume: 30, Issue:2

    Topics: Adult; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Lupus Vulgaris; Pregnancy; Pregna

1989
Implications of sino-aortic baroreceptor reflex dysfunction in severe preeclampsia.
    Obstetrics and gynecology, 1989, Volume: 74, Issue:1

    Topics: Adult; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hydralazine; Pre-Ec

1989
[Hypertension in pregnancy: proposed monitoring and therapy].
    Minerva ginecologica, 1985, Volume: 37, Issue:10

    Topics: Adrenergic beta-Antagonists; Captopril; Diuretics; Female; Follow-Up Studies; Humans; Hydralazine; H

1985
Antihypertensive therapy in pregnancy directed by noninvasive hemodynamic monitoring.
    American journal of perinatology, 1989, Volume: 6, Issue:1

    Topics: Atenolol; Cardiac Output; Female; Hemodynamics; Humans; Hydralazine; Hypertension; Pregnancy; Pregna

1989
Fetal premature atrial contractions associated with hydralazine.
    American journal of obstetrics and gynecology, 1989, Volume: 160, Issue:1

    Topics: Adult; Arrhythmias, Cardiac; Blood Pressure; Echocardiography; Female; Fetal Diseases; Heart Rate; H

1989
Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes.
    The Journal of biological chemistry, 1989, Feb-05, Volume: 264, Issue:4

    Topics: Carrier Proteins; Cations, Monovalent; Desipramine; Female; Humans; Hydralazine; Imipramine; Kinetic

1989
Elevated blood pressure during pregnancy.
    Hospital practice (Office ed.), 1986, Feb-15, Volume: 21, Issue:2

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Me

1986
The effect of hydralazine on steady-state plasma concentrations of metoprolol in pregnant hypertensive women.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:2

    Topics: Adult; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Meto

1988
Dihydralazine and the uteroplacental blood flow.
    American journal of obstetrics and gynecology, 1988, Volume: 158, Issue:2

    Topics: Dihydralazine; Female; Humans; Hydralazine; Hypertension; Placenta; Pregnancy; Pregnancy Complicatio

1988
Hypertensive crisis in L & D.
    The American journal of nursing, 1988, Volume: 88, Issue:3

    Topics: Adult; Critical Care; Diazoxide; Female; Humans; Hydralazine; Hypertension; Magnesium Sulfate; Nitro

1988
Comparison of nitroprusside and hydralazine in isolated uterine arteries from pregnant and nonpregnant patients.
    Anesthesiology, 1988, Volume: 68, Issue:4

    Topics: Arteries; Female; Ferricyanides; Humans; Hydralazine; In Vitro Techniques; Muscle Contraction; Muscl

1988
Effect of the antihypertensive drug hydralazine on mineral metabolism in the rat.
    Toxicology letters, 1988, Volume: 41, Issue:3

    Topics: Animals; Copper; Dose-Response Relationship, Drug; Female; Hydralazine; Iron; Manganese; Minerals; P

1988
Prenatal and postnatal hydralazine treatment does not prevent renal vessel wall thickening in SHR despite the absence of hypertension.
    Circulation research, 1988, Volume: 63, Issue:3

    Topics: Animals; Animals, Newborn; Blood Pressure; Blood Vessels; Female; Hydralazine; Muscle, Smooth, Vascu

1988
Chronic measurement, using a Doppler probe, of uterine artery flow in the gravid guinea-pig.
    Journal of reproduction and fertility, 1986, Volume: 77, Issue:1

    Topics: Angiotensin II; Animals; Blood Flow Velocity; Epinephrine; Female; Guinea Pigs; Hydralazine; Models,

1986
Cardiovascular actions of dihydralazine as modified by dietary linoleic acid.
    Biomedica biochimica acta, 1986, Volume: 45, Issue:8

    Topics: Animals; Aorta, Abdominal; Aspirin; Blood Pressure; Dietary Fats; Dihydralazine; Epoprostenol; Fatty

1986
The use of dihydralazine infusion in the management of severe hypertension in pregnancy.
    The Central African journal of medicine, 1986, Volume: 32, Issue:6

    Topics: Adult; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Infusions, Intravenous; Pregnancy;

1986
The management of severe preeclampsia with intravenous magnesium sulphate, hydralazine and central venous catheterization.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1987, Volume: 27, Issue:2

    Topics: Acute Disease; Catheterization, Central Venous; Drug Therapy, Combination; Female; Humans; Hydralazi

1987
Fetal distress after hydralazine therapy for severe pregnancy-induced hypertension.
    Southern medical journal, 1986, Volume: 79, Issue:5

    Topics: Acute Disease; Cesarean Section; Eclampsia; Female; Fetal Distress; Gestational Age; Humans; Hydrala

1986
Effect of antihypertensive drugs on catechol-O-methyltransferase and monoamine oxidase activity in human term placental explants.
    Gynecologic and obstetric investigation, 1986, Volume: 21, Issue:3

    Topics: Antihypertensive Agents; Catechol O-Methyltransferase; Dose-Response Relationship, Drug; Female; Hum

1986
[Studies of heart function using apex cardiography in pregnancy-induced hypertension before and following therapy with dihydralazine sulfate].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1986, Apr-15, Volume: 41, Issue:8

    Topics: Blood Pressure; Dihydralazine; Female; Hemodynamics; Humans; Hydralazine; Kinetocardiography; Myocar

1986
Acute effects of dihydralazine mesylate, furosemide, and metoprolol on maternal hemodynamics in pregnancy-induced hypertension.
    American journal of obstetrics and gynecology, 1986, Volume: 155, Issue:1

    Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Chorionic Villi; Dihydralazine; Female; Furosem

1986
Beta-blockade-vasodilator therapy in peripartum cardiomyopathy.
    The Journal of the Association of Physicians of India, 1986, Volume: 34, Issue:7

    Topics: Adolescent; Cardiomyopathy, Dilated; Female; Humans; Hydralazine; Pregnancy; Propranolol

1986
Fetal distress with hydralazine.
    Southern medical journal, 1987, Volume: 80, Issue:3

    Topics: Female; Fetal Distress; Humans; Hydralazine; Pregnancy

1987
The effect of hydralazine on placental perfusion in the spontaneously hypertensive rat.
    American journal of obstetrics and gynecology, 1987, Volume: 156, Issue:2

    Topics: Animals; Antihypertensive Agents; Female; Hydralazine; Hypertension; Perfusion; Placenta; Pregnancy;

1987
Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids.
    Obstetrics and gynecology, 1985, Volume: 65, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Blood Pressure; Dihydralazine; Female; Fetal Heart; Humans; Hydralazin

1985
Studies on the kinetics and distribution of dihydralazine in pregnancy.
    Biological research in pregnancy and perinatology, 1986, Volume: 7, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Amniotic Fluid; Dihydralazine; Female; Fetal Blood; Humans;

1986
Severe preeclampsia with persistent postpartum hemolysis and thrombocytopenia treated by plasmapheresis.
    Obstetrics and gynecology, 1985, Volume: 65, Issue:3 Suppl

    Topics: Adult; Anemia, Hemolytic; Aspartate Aminotransferases; Blood Transfusion; Blood Urea Nitrogen; Femal

1985
Diagnosis and management of malignant hypertension.
    Comprehensive therapy, 1985, Volume: 11, Issue:3

    Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Malignant; Kidney Function Tests

1985
Plasma prolactin concentrations and pregnancy-induced hypertension.
    Southern medical journal, 1985, Volume: 78, Issue:5

    Topics: Adult; Apgar Score; Birth Weight; Circadian Rhythm; Female; Gestational Age; Humans; Hydralazine; Hy

1985
Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester.
    American journal of obstetrics and gynecology, 1985, May-01, Volume: 152, Issue:1

    Topics: Administration, Oral; Antihypertensive Agents; Bed Rest; Birth Weight; Delivery, Obstetric; Diuretic

1985
Hypertension in pregnancy. A study of 142 women presenting before 32 weeks' gestation.
    The Medical journal of Australia, 1985, Jul-08, Volume: 143, Issue:1

    Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hydralazine; Hypertension; Infant Mor

1985
Cardiovascular alterations in severe pregnancy-induced hypertension seen with an intravenously given hydralazine bolus.
    Surgery, gynecology & obstetrics, 1985, Volume: 161, Issue:3

    Topics: Adult; Blood Pressure; Cardiac Output; Female; Heart Rate; Humans; Hydralazine; Hypertension; Pregna

1985
Management of autonomic hyperreflexia associated with a low thoracic spinal cord lesion.
    American journal of obstetrics and gynecology, 1985, Sep-15, Volume: 153, Issue:2

    Topics: Adult; Autonomic Nervous System Diseases; Cesarean Section; Female; Humans; Hydralazine; Obstetric L

1985
Hemodynamic effects of intravenous hydralazine in pregnant women with severe hypertension.
    Obstetrics and gynecology, 1985, Volume: 66, Issue:4

    Topics: Blood Pressure; Body Surface Area; Cardiac Output; Echocardiography; Female; Hemodynamics; Humans; H

1985
Management of severe hypertension.
    The American journal of cardiology, 1973, Sep-20, Volume: 32, Issue:4

    Topics: Benzothiadiazines; Blood Pressure; Clonidine; Diazoxide; Diet, Sodium-Restricted; Disseminated Intra

1973
Periodic dialysis in terminal uremia.
    JAMA, 1967, Feb-06, Volume: 199, Issue:6

    Topics: Adolescent; Adult; Anemia; Arthritis; Child; Female; Gastrointestinal Hemorrhage; Glaucoma; Glomerul

1967
Effect of certain drugs on perfused human placenta. 8. Angiotensin-II antagonists.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:2

    Topics: Acetates; Angiotensin II; Atropine; Blood Pressure Determination; Cobalt; Cocaine; Cyproheptadine; D

1968
Dynamics of uterine circulation in pregnant and nonpregnant sheep.
    The American journal of physiology, 1970, Volume: 218, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Female; Homeostasis; Hydralazine; Injections, Intra-Arteria

1970
Effect of certain drugs on perfused human placenta. IX. Mode of action of angiotensin.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:5

    Topics: Angiotensin II; Blood Vessels; Constriction; Dipyridamole; Ethanolamines; Female; Humans; Hydralazin

1969
A critical survey of drugs used in the treatment of hypertensive crises of pregnancy.
    The Medical journal of Australia, 1974, Aug-17, Volume: 2, Issue:7

    Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Barbiturates; Chlormethiazole; Clonidine; Diazepam;

1974
[Pregnancy toxemia. Mechanism, prevention and treatment].
    La Revue du praticien, 1974, Nov-11, Volume: 24, Issue:51

    Topics: Blood Coagulation Disorders; Diet, Sodium-Restricted; Diuretics; Eclampsia; Edema; Female; Hospitali

1974
Intravenous chlormethiazole in the management of severe pre-eclampsia.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1973, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Chlormethiazole; Chlo

1973
The use of diazepam and hydrallazine in the treatment of severe pre-eclampsia.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1972, Volume: 79, Issue:3

    Topics: Adult; Blood Pressure; Diazepam; Ethanol; Female; Gestational Age; Humans; Hydralazine; Hypothermia;

1972
The management of hypertension during pregnancy.
    The Journal of reproductive medicine, 1972, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Blood Pressure; Clinical Laboratory Techniques; Diagnosis, Differential; Dihydrox

1972
[Therapy of EPH gestosis].
    Deutsche medizinische Wochenschrift (1946), 1973, Jul-06, Volume: 98, Issue:27

    Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans;

1973
Diuretic-hypotensive therapy and fetal prognosis in toxaemia of pregnancy. 1. Fetal prognosis in 705 selected cases.
    Annales chirurgiae et gynaecologiae Fenniae, 1973, Volume: 62, Issue:3

    Topics: Acetazolamide; Ammonium Chloride; Antihypertensive Agents; Barbiturates; Birth Weight; Chlorothiazid

1973
Active management of severe pre-eclampsia.
    Canadian Medical Association journal, 1973, Dec-15, Volume: 109, Issue:12

    Topics: Adult; Animals; Apgar Score; Birth Weight; Delivery, Obstetric; Diazepam; Female; Fetal Death; Human

1973
Galactorrhea and Parkinson-like syndrome: an adverse effect of alpha-methyldopa.
    Metabolism: clinical and experimental, 1970, Volume: 19, Issue:12

    Topics: Adolescent; Amenorrhea; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Kidney Transp

1970
Effect of toxemia therapy on uterine dynamics.
    American journal of obstetrics and gynecology, 1969, Sep-01, Volume: 105, Issue:1

    Topics: Amniotic Fluid; Animals; Arteries; Blood Pressure; Eclampsia; Female; Haplorhini; Humans; Hydralazin

1969
[Therapy of pregnancy toxemias (EPH-gestosis, preeclampsia)].
    Deutsche medizinische Wochenschrift (1946), 1972, Apr-28, Volume: 97, Issue:17

    Topics: Blood Pressure Determination; Chlorpromazine; Dextrans; Diazepam; Diet Therapy; Edema; Female; Human

1972
[Indication for cesarean section: pregnancy toxemia].
    Sanfujinka no jissai. Practice of gynecology and obstetrics, 1972, Volume: 21, Issue:1

    Topics: Adult; Cesarean Section; Chlorpromazine; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Rese

1972
Coexistent trophoblastic tumor and viable pregnancy.
    Obstetrics and gynecology, 1971, Volume: 38, Issue:6

    Topics: Adult; Choriocarcinoma; Chorionic Gonadotropin; Female; Humans; Hydatidiform Mole; Hydralazine; Hype

1971
[On a new hypotensive pharmacological association in pregnancy with hypertension].
    Minerva ginecologica, 1971, Sep-30, Volume: 23, Issue:18

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Carbamates; Creatinine; Electrolytes; Female; Humans

1971
Clinical and laboratory observations on eclampsia.
    American journal of obstetrics and gynecology, 1967, Nov-15, Volume: 99, Issue:6

    Topics: Blood Chemical Analysis; Blood Volume Determination; Cesarean Section; Delivery, Obstetric; Eclampsi

1967
[Cerebral anoxia during treatment of severe toxemias with hypotensive infusion].
    Ugeskrift for laeger, 1969, Nov-06, Volume: 131, Issue:45

    Topics: Adult; Chlorpromazine; Female; Humans; Hydralazine; Hypoxia, Brain; Pre-Eclampsia; Pregnancy

1969
Effects of hydralazine on uteroplacental and fetal circulations.
    American journal of obstetrics and gynecology, 1970, Oct-01, Volume: 108, Issue:3

    Topics: Animals; Animals, Newborn; Arteries; Blood Pressure; Carbon Dioxide; Female; Fetus; Heart Rate; Hydr

1970
Pharmacogenetics.
    Transactions of the Medical Society of London, 1970, Volume: 86

    Topics: Aged; Cortisone; Enzyme Induction; Female; Glaucoma; Humans; Hydralazine; Intraocular Pressure; Ison

1970
[Therapy of hypertension].
    Die Medizinische Welt, 1971, Jan-16, Volume: 3

    Topics: Adrenal Gland Neoplasms; Aniline Compounds; Antihypertensive Agents; Diuretics; Female; Guanethidine

1971
Aggressive toxemia management (preeclampsia and eclampsia).
    Obstetrics and gynecology, 1969, Volume: 33, Issue:5

    Topics: Antihypertensive Agents; Cesarean Section; Female; Humans; Hydralazine; Magnesium Sulfate; Pre-Eclam

1969
Essential hypertension complicating pregnancy: Factors affecting the fetal mortality.
    Proceedings of the Royal Society of Medicine, 1966, Volume: 59, Issue:9

    Topics: Adult; Female; Fetal Death; Humans; Hydralazine; Hypertension; Middle Aged; Pregnancy; Pregnancy Com

1966
[How can the difficulties in the antihypertensive therapy of prolonged pregnancy be prevented?].
    Zentralblatt fur Gynakologie, 1966, Jun-11, Volume: 88, Issue:24

    Topics: Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Phytotherapy; Plants, Med

1966