Page last updated: 2024-10-28

hydralazine and Prediabetic State

hydralazine has been researched along with Prediabetic State in 3 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Prediabetic State: The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
" placebo (H-HeFT) and 2) if metformin reduces the incidence of death, worsening heart failure, acute myocardial infarction, and stroke vs."9.41The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chr ( Abdulla, J; Barasa, A; Bibby, BM; Bruun, NE; Brønnum-Schou, J; Bøtker, HE; Bøttcher, M; Dodt, K; Eiskjær, H; Gislason, G; Gustafsson, F; Hansen, VB; Hassager, C; Hollingdal, M; Høfsten, DE; Jonczy, B; Knudsen, AS; Kristensen, SL; Køber, L; Larsen, AH; Lomholdt, J; Madsen, JS; Mahboubi, K; Mellemkjær, S; Mikkelsen, KV; Møller, J; Nielsen, G; Nielsen, OW; Nørrelund, H; Poenaru, MP; Poulsen, MK; Raymond, I; Refsgaard, J; Schou, M; Serup-Hansen, K; Sillesen, K; Steffensen, FH; Torp-Petersen, C; Vraa, S; Wiggers, H, 2021)
" placebo (H-HeFT) and 2) if metformin reduces the incidence of death, worsening heart failure, acute myocardial infarction, and stroke vs."5.41The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chr ( Abdulla, J; Barasa, A; Bibby, BM; Bruun, NE; Brønnum-Schou, J; Bøtker, HE; Bøttcher, M; Dodt, K; Eiskjær, H; Gislason, G; Gustafsson, F; Hansen, VB; Hassager, C; Hollingdal, M; Høfsten, DE; Jonczy, B; Knudsen, AS; Kristensen, SL; Køber, L; Larsen, AH; Lomholdt, J; Madsen, JS; Mahboubi, K; Mellemkjær, S; Mikkelsen, KV; Møller, J; Nielsen, G; Nielsen, OW; Nørrelund, H; Poenaru, MP; Poulsen, MK; Raymond, I; Refsgaard, J; Schou, M; Serup-Hansen, K; Sillesen, K; Steffensen, FH; Torp-Petersen, C; Vraa, S; Wiggers, H, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Wiggers, H1
Køber, L1
Gislason, G1
Schou, M1
Poulsen, MK1
Vraa, S1
Nielsen, OW1
Bruun, NE1
Nørrelund, H1
Hollingdal, M1
Barasa, A1
Bøttcher, M1
Dodt, K1
Hansen, VB1
Nielsen, G1
Knudsen, AS1
Lomholdt, J1
Mikkelsen, KV1
Jonczy, B1
Brønnum-Schou, J1
Poenaru, MP1
Abdulla, J1
Raymond, I1
Mahboubi, K1
Sillesen, K1
Serup-Hansen, K1
Madsen, JS1
Kristensen, SL1
Larsen, AH1
Bøtker, HE1
Torp-Petersen, C1
Eiskjær, H1
Møller, J1
Hassager, C1
Steffensen, FH1
Bibby, BM1
Refsgaard, J1
Høfsten, DE1
Mellemkjær, S1
Gustafsson, F1
Satoh, M1
Nagasu, H1
Haruna, Y1
Ihoriya, C1
Kadoya, H1
Sasaki, T1
Kashihara, N1
Nagai, Y1
Yao, L1
Kobori, H1
Miyata, K1
Ozawa, Y1
Miyatake, A1
Yukimura, T1
Shokoji, T1
Kimura, S1
Kiyomoto, H1
Kohno, M1
Abe, Y1
Nishiyama, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-blind, Placebo Controlled Study (DANHEART): Hydralazine-ISDN in Patients With Chronic Heart Failure - Hydralazine Heart Failure Trial (H-HeFT) and Metformin in Patients With Chronic Heart Failure and Diabetes or Insulin Resistance - M[NCT03514108]Phase 41,500 participants (Anticipated)Interventional2018-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for hydralazine and Prediabetic State

ArticleYear
The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chr
    American heart journal, 2021, Volume: 231

    Topics: Aged; Chronic Disease; Denmark; Diabetes Mellitus; Double-Blind Method; Drug Combinations; Female; H

2021

Other Studies

2 other studies available for hydralazine and Prediabetic State

ArticleYear
Hypertension promotes islet morphological changes with vascular injury on pre-diabetic status in SHRsp rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:3

    Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Hydral

2014
Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; A

2005