hydralazine has been researched along with Osteogenic Sarcoma in 3 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to investigate the effects of sodium valproate (VPA), a histone deacetylase inhibitor, in combination with hydralazine hydrochloride (Hy), a DNA methylation inhibitor, on the expression of VEGI and its related receptors in human osteosarcoma (OS) cell lines and human microvascular endothelial (HMVE) cells." | 7.91 | Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells. ( Fujihara, Y; Futani, H; Kobayashi, K; Kumanishi, S; Nakasho, K; Nishiura, H; Yamanegi, K; Yoshiya, S, 2019) |
| "We investigated the effects of valproic acid (VPA), a histone deacetylase inhibitor, in combination with hydralazine, a DNA methylation inhibitor, on the expression of cell-surface Fas and MHC-class I-related chain molecules A and B (MICA and B), the ligands of NKG2D which is an activating receptor of NK cells, and on production of their soluble forms in HOS, U-2 OS and SaOS-2 human osteosarcoma cell lines." | 7.78 | Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma cells to Fas- and NK cell-mediated cell death. ( Fukunaga, S; Futani, H; Hata, M; Kato-Kogoe, N; Kobayashi, K; Nakasho, K; Ohyama, H; Okamura, H; Terada, N; Yamada, N; Yamane, J; Yamanegi, K, 2012) |
| " The aim of the present study was to investigate the effects of sodium valproate (VPA), a histone deacetylase inhibitor, in combination with hydralazine hydrochloride (Hy), a DNA methylation inhibitor, on the expression of VEGI and its related receptors in human osteosarcoma (OS) cell lines and human microvascular endothelial (HMVE) cells." | 3.91 | Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells. ( Fujihara, Y; Futani, H; Kobayashi, K; Kumanishi, S; Nakasho, K; Nishiura, H; Yamanegi, K; Yoshiya, S, 2019) |
| "We investigated the effects of valproic acid (VPA), a histone deacetylase inhibitor, in combination with hydralazine, a DNA methylation inhibitor, on the expression of cell-surface Fas and MHC-class I-related chain molecules A and B (MICA and B), the ligands of NKG2D which is an activating receptor of NK cells, and on production of their soluble forms in HOS, U-2 OS and SaOS-2 human osteosarcoma cell lines." | 3.78 | Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma cells to Fas- and NK cell-mediated cell death. ( Fukunaga, S; Futani, H; Hata, M; Kato-Kogoe, N; Kobayashi, K; Nakasho, K; Ohyama, H; Okamura, H; Terada, N; Yamada, N; Yamane, J; Yamanegi, K, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumanishi, S | 1 |
| Yamanegi, K | 2 |
| Nishiura, H | 1 |
| Fujihara, Y | 1 |
| Kobayashi, K | 2 |
| Nakasho, K | 2 |
| Futani, H | 2 |
| Yoshiya, S | 1 |
| Yamane, J | 1 |
| Kato-Kogoe, N | 1 |
| Ohyama, H | 1 |
| Yamada, N | 1 |
| Hata, M | 1 |
| Fukunaga, S | 1 |
| Okamura, H | 1 |
| Terada, N | 1 |
| Fried, R | 1 |
| Steinherz, LJ | 1 |
| Levin, AR | 1 |
| Linday, L | 1 |
| Tan, CT | 1 |
| Miller, D | 1 |
3 other studies available for hydralazine and Osteogenic Sarcoma
| Article | Year |
|---|---|
Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells.
Topics: Bone Neoplasms; Cell Line; Cell Line, Tumor; Drug Synergism; Endothelial Cells; Enzyme Inhibitors; E | 2019 |
Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma cells to Fas- and NK cell-mediated cell death.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytotoxicity, Immunologi | 2012 |
Use of hydralazine for intractable cardiac failure in childhood.
Topics: Antineoplastic Agents; Child; Chronic Disease; Female; Heart Failure; Humans; Hydralazine; Maxillary | 1980 |