hydralazine has been researched along with Muscle Relaxation in 17 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the potency of vasodilatory drugs in hypoxia, we studied the effects of nitroglycerin (NTG), prostaglandin E1 (PGE1), and hydralazine on porcine coronary artery constricted with endothelin-1 (ET-1) in both oxygenated and hypoxic conditions." | 7.69 | Hypoxia modifies the vasodilatory effects of nitroglycerin, prostaglandin E1, and hydralazine on isolated porcine coronary arteries. ( Fujihara, H; Fujiwara, N; Fukuda, S; Sakuma, K; Shimoji, K; Tanaka, T; Toriumi, T; Tsukui, A, 1994) |
| "To evaluate the potency of vasodilatory drugs in hypoxia, we studied the effects of nitroglycerin (NTG), prostaglandin E1 (PGE1), and hydralazine on porcine coronary artery constricted with endothelin-1 (ET-1) in both oxygenated and hypoxic conditions." | 3.69 | Hypoxia modifies the vasodilatory effects of nitroglycerin, prostaglandin E1, and hydralazine on isolated porcine coronary arteries. ( Fujihara, H; Fujiwara, N; Fukuda, S; Sakuma, K; Shimoji, K; Tanaka, T; Toriumi, T; Tsukui, A, 1994) |
| "Hydralazine-treated SHR had normalized blood pressure but unaltered low ICP response." | 1.33 | Increased intracavernosal pressure response in hypertensive rats after chronic hemin treatment. ( Shamloul, R; Wang, R, 2006) |
| "When adenosine was added, relaxation was elicited with concomitant increase in cAMP, but with no significant change in cGMP." | 1.27 | Augmentation of adenosine-induced relaxation response with hydralazine in aortic strips. ( Azuma, H; Ishikawa, M; Mizushima-Kasahara, K; Sekizaki, S, 1988) |
| "Hydralazine was effective at similar concentrations on these three types of contraction." | 1.27 | Relaxant effects of pinacidil, nicorandil, hydralazine and nifedipine as studied in the porcine coronary artery and guinea-pig taenia coli. ( Imai, S; Matsui, K; Ogawa, Y, 1986) |
| " CaCl2 dose-response (in the presence of 10(-5) mol." | 1.27 | Mechanism of hydralazine-induced relaxation of arterial smooth muscle. ( Aloamaka, CP; Ebeigbe, AB, 1985) |
| "Dihydralazine was found to have a very low potency in all types of vessels, and no difference between the effects on arterial and venous preparations was found." | 1.26 | Comparison of the in vitro effects of prazosin, nifedipine, and dihydralazine in isolated human mesenteric and crural vessels. ( Andersson, KE; Mikkelsen, E; Pedersen, OL, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grisk, O | 1 |
| Lother, U | 1 |
| Gabriëls, G | 1 |
| Rettig, R | 1 |
| Vidrio, H | 1 |
| González-Romo, P | 1 |
| Alvarez, E | 1 |
| Alcaide, C | 1 |
| Orallo, F | 3 |
| Shamloul, R | 1 |
| Wang, R | 1 |
| Chevillard, C | 1 |
| Saiag, B | 1 |
| Worcel, M | 1 |
| Fukuda, S | 1 |
| Sakuma, K | 1 |
| Tsukui, A | 1 |
| Fujiwara, N | 1 |
| Tanaka, T | 1 |
| Fujihara, H | 1 |
| Toriumi, T | 1 |
| Shimoji, K | 1 |
| Gil-Longo, J | 1 |
| de los Reyes Laguna, M | 1 |
| Verde, I | 1 |
| Castro, ME | 1 |
| Fontenla, JA | 1 |
| Calleja, JM | 1 |
| Ravina, E | 1 |
| Teran, C | 1 |
| Wei, S | 1 |
| Kasuya, Y | 1 |
| Yanagisawa, M | 1 |
| Kimura, S | 1 |
| Masaki, T | 1 |
| Goto, K | 1 |
| Ezimokhai, M | 1 |
| Janis, RA | 1 |
| Diamond, J | 1 |
| Pedersen, OL | 1 |
| Mikkelsen, E | 1 |
| Andersson, KE | 1 |
| Haegele, KD | 1 |
| McLean, AJ | 1 |
| du Souich, P | 1 |
| Barron, K | 1 |
| Laquer, J | 1 |
| McNay, JL | 1 |
| Carrier, O | 1 |
| Grichois, ML | 1 |
| Blanc, J | 1 |
| Deckert, V | 1 |
| Elghozi, JL | 1 |
| DeFeo, TT | 1 |
| Morgan, KG | 1 |
| Azuma, H | 1 |
| Mizushima-Kasahara, K | 1 |
| Sekizaki, S | 1 |
| Ishikawa, M | 1 |
| Matsui, K | 1 |
| Ogawa, Y | 1 |
| Imai, S | 1 |
| Eleno, N | 1 |
| Botana, L | 1 |
| Espinosa, J | 1 |
| Cadavid, I | 1 |
| Ebeigbe, AB | 1 |
| Aloamaka, CP | 1 |
17 other studies available for hydralazine and Muscle Relaxation
| Article | Year |
|---|---|
Influence of neonatal sympathectomy on proximal renal resistance artery function in spontaneously hypertensive rats.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Channels, L-Typ | 2005 |
Hydralazine decreases sodium nitroprusside-induced rat aortic ring relaxation and increased cGMP production by rat aortic myocytes.
Topics: Animals; Aorta; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Hydralazine; Male; Multienzyme C | 2005 |
Increased intracavernosal pressure response in hypertensive rats after chronic hemin treatment.
Topics: Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug | 2006 |
Hydralazine: mode of action at the neuroarterial junction.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Hydralazine; Hypertension; In Vitro Techniques; | 1980 |
Hypoxia modifies the vasodilatory effects of nitroglycerin, prostaglandin E1, and hydralazine on isolated porcine coronary arteries.
Topics: Alprostadil; Analysis of Variance; Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Endothelins; H | 1994 |
Pyridazine derivatives. XI: Antihypertensive activity of 3-hydrazinocycloheptyl[1,2-c]pyridazine and its hydrazone derivatives.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium; Calcium Radioisotopes; Female; Hydralazi | 1993 |
Studies on endothelium-dependent vasorelaxation by hydralazine in porcine coronary artery.
Topics: Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Dactinomycin; Endothel | 1997 |
The alterations of vascular smooth muscle reactivity in vitro by human chorionic gonadotrophin.
Topics: Acetylcholine; Animals; Blood Pressure; Chorionic Gonadotropin; Estradiol; Female; Hydralazine; In V | 1998 |
Relationship between cyclic nucleotide levels and drug-induced relaxation of smooth muscle.
Topics: Animals; Cyclic AMP; Cyclic GMP; Diazoxide; Drug Interactions; Female; Guinea Pigs; Hydralazine; In | 1979 |
Comparison of the in vitro effects of prazosin, nifedipine, and dihydralazine in isolated human mesenteric and crural vessels.
Topics: Adolescent; Adult; Aged; Calcium; Dihydralazine; Humans; Hydralazine; In Vitro Techniques; Leg; Mese | 1979 |
Identification of hydrallazine and hydrallazine hydrazone metabolites in human body fluids and quantitative in vitro comparisons of their smooth muscle relaxant activity.
Topics: Animals; Aorta; Humans; Hydralazine; Hydrazones; In Vitro Techniques; Mass Spectrometry; Muscle Cont | 1978 |
Differential effects of enalapril and hydralazine on short-term variability of blood pressure and heart rate in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Drinking Behavior; Enalapril; Heart Rate; Hydr | 1992 |
Calcium-force coupling mechanisms during vasodilator-induced relaxation of ferret aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Carnivora; Colforsin; Ferrets; Hydralazine; In Vitro Techniques; | 1989 |
Augmentation of adenosine-induced relaxation response with hydralazine in aortic strips.
Topics: Adenosine; Animals; Aorta; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactio | 1988 |
Relaxant effects of pinacidil, nicorandil, hydralazine and nifedipine as studied in the porcine coronary artery and guinea-pig taenia coli.
Topics: Animals; Caffeine; Colon; Coronary Vessels; Female; Guanidines; Guinea Pigs; Hydralazine; In Vitro T | 1986 |
Hydralazine-relaxing effect on rat aorta is not mediated through changes in ATPase activity.
Topics: Adenosine Triphosphatases; Animals; Aorta, Thoracic; Hydralazine; In Vitro Techniques; Male; Muscle | 1987 |
Mechanism of hydralazine-induced relaxation of arterial smooth muscle.
Topics: Animals; Barium; Barium Compounds; Calcium; Calcium Chloride; Chlorides; Dose-Response Relationship, | 1985 |