Page last updated: 2024-10-28

hydralazine and Muscle Contraction

hydralazine has been researched along with Muscle Contraction in 59 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"We studied the effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam (a dopamine D1-agonist) on isolated human umbilical arteries (HUA) from patients classified as normotensive and with pregnancy-induced hypertension (PIH)."3.72The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. ( Arias, ME; Levy, JH; Sato, N; Szlam, F; Tanaka, KA; Tsuda, A, 2003)
" Budralazine was orally effective against various types of hypertension in rats and it, like reserpine but unlike hydralazine, produced a much greater pressure reduction in hypertensive than in normotensive rats."3.66Pharmacology of budralazine, a new antihypertensive drug. ( Akashi, A; Chiba, T; Hashimoto, H; Suzuki, I, 1978)
"Hydralazine is a hydrazine derivative used clinically as a vasodilator and antihypertensive agent."1.32Effects of hydrazine derivatives on vascular smooth muscle contractility, blood pressure and cGMP production in rats: comparison with hydralazine. ( Alvarez, E; Fernández, G; Medina, M; Orallo, F; Vidrio, H, 2003)
"Treatment with ramipril reduced blood pressure and force development in response to Bay K8644 in adult SHRSP, although not to levels of WKY rats, whereas WKY rats were unaffected by treatment."1.29Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats. ( Traub, O; Webb, RC, 1993)
"The combination of hydralazine and nitrates has been shown to provide long-term benefit in congestive heart failure, despite a nitrate dosage that should induce tolerance."1.29Interaction between hydralazine and nitrovasodilators in vascular smooth muscle. ( Berkenboom, G; Fontaine, J; Unger, P, 1993)
"Amlodipine is a dihydropyridine that blocks L-type channels, thereby preventing entry of Ca2+ into the muscle."1.29Effect of chronic blood pressure reduction on soleus muscle contractile properties in spontaneously hypertensive rats. ( Atherley, R; Carlsen, RC; Gray, SD, 1994)
"Hydralazine (0."1.28Comparison of the effects of hydralazine and nifedipine on contractions and 45Ca influx of rat aorta. ( Bardán, B; Calleja, JM; Gil-Longo, J; Orallo, F, 1991)
"Phentolamine (10(-6) M) pretreatment had no effect on the ouabain-induced contraction but partially suppressed it in both SHR and WKY aortas when diltiazem (10(-5) M) was also added."1.27Ouabain-induced contraction of vascular smooth muscle in spontaneously hypertensive rats and the effect of hydralazine. ( Iwasaki, T; Kawai, Y; Miyata, S; Morita, S; Nagai, K, 1988)
" Substantially, cadralazine does not exert any effect on cumulative dose-response curves of these agonists in both vessel preparations even with the highest concentration of 10(-4) mol/l."1.27Effects of cadralazine on contractions induced by norepinephrine, serotonin, angiotensin II and K+ in rabbit aortic and renal arterial strips. ( Higashio, T; Kuroda, K, 1988)
" CaCl2 dose-response (in the presence of 10(-5) mol."1.27Mechanism of hydralazine-induced relaxation of arterial smooth muscle. ( Aloamaka, CP; Ebeigbe, AB, 1985)
"Hydralazine prevented the increase of arterial pressure and the decrease of stress developed to NA by the aortic strips from both SHR and DOCA/salt rats."1.26Hydralazine prevents changes in the contractile response of aortic but not portal vein strips in hypertensive rats. ( Pang, CC; Sutter, MC, 1980)
"Dihydralazine was found to have a very low potency in all types of vessels, and no difference between the effects on arterial and venous preparations was found."1.26Comparison of the in vitro effects of prazosin, nifedipine, and dihydralazine in isolated human mesenteric and crural vessels. ( Andersson, KE; Mikkelsen, E; Pedersen, OL, 1979)
" Dose-response relationships to K+ were determined in isolated strips of rabbit aorta."1.26Comparative evaluation of the in vitro effects of hydralazine and hydralazine acetonide on arterial smooth muscle. ( Barron, K; Carrier, O; Du Souich, P; Haegele, KD; McLean, AJ; McNay, JL, 1977)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199043 (72.88)18.7374
1990's13 (22.03)18.2507
2000's2 (3.39)29.6817
2010's1 (1.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chapleo, CB1
Doxey, JC1
Myers, PL1
Evans, JM1
Fake, CS1
Hamilton, TC1
Poyser, RH1
Watts, EA1
Lemkens, P1
Spijkers, LJ1
Meens, MJ1
Nelissen, J1
Janssen, B1
Peters, SL1
Schiffers, PM1
De Mey, JG1
Sato, N1
Tanaka, KA1
Szlam, F1
Tsuda, A1
Arias, ME1
Levy, JH1
Vidrio, H1
Fernández, G1
Medina, M1
Alvarez, E1
Orallo, F5
Kreye, VA2
Mellow, MH1
Jacobs, M1
Diamond, J4
Janis, RA3
Albrecht, T1
Speelman, DJ1
Steinsland, OS1
Lipe, S2
Moulds, RF3
Wilson, JR1
Hoyt, RW1
Ferraro, N1
Janicki, JS1
Weber, KT1
Hermsmeyer, K2
Trapani, A1
Abel, PW1
Worcel, M3
Hay, DW1
Wadsworth, RM1
Elkayam, U1
McKay, CR1
Weber, L1
Eisenberg, D1
Rahimtoola, SH1
Khayyal, M1
Gross, F1
Krishnamurty, VS1
Shaikh, MI1
Pang, CC2
Sutter, MC2
Traub, O2
Webb, RC2
Unger, P1
Berkenboom, G1
Fontaine, J1
Moina, MJ1
Bardan, B2
Campos Toimil, M1
Alzueta, AF1
Gil-Longo, J3
Gray, SD1
Carlsen, RC1
Atherley, R1
Campos-Toimil, M2
Verde, I1
Loza, I1
Fernández-Alzueta, A1
Lloyd, MC1
Nasu, T2
Yanagimoto, S2
Shimamura, K1
Matsuda, K1
Sekiguchi, F1
Sunano, S1
Shibata, H1
Estévez, I1
Raviña, E1
Ezimokhai, M1
Ishii, A1
Kubo, K1
Deguchi, T1
Tanaka, M1
Pedersen, OL1
Mikkelsen, E1
Andersson, KE1
Barron, K4
Carrier, O4
Haegele, KD4
McLean, AJ4
McNay, JL4
Du Souich, P4
Briggs, A1
Laquer, J1
Akashi, A1
Chiba, T1
Suzuki, I1
Hashimoto, H1
Baker, JR1
Hedwall, PR1
Calleja, JM1
Nakajima, S1
Kurokawa, K1
Imamura, N1
Ueda, M1
Sada, T1
Koike, H1
Miyamoto, M1
DeFeo, TT1
Morgan, KG1
Morita, S1
Iwasaki, T1
Nagai, K1
Miyata, S1
Kawai, Y1
Nelson, SH1
Suresh, MS1
Higashio, T2
Kuroda, K2
Ebeigbe, AB1
Aloamaka, CP1
Perry, HM1
Schoepfle, E1
Bourgoignie, J1
Ward, CO1
Gautieri, RF1
Lamid, S1
Wolff, FW1
Loev, B1
Goodman, MM1
Snader, MK1
Tedeschi, R1
Macko, E1
Uchida, E1
Bohr, DF1

Reviews

2 reviews available for hydralazine and Muscle Contraction

ArticleYear
Direct vasodilators with unknown modes of action: the nitro-compounds and hydralazine.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 4

    Topics: Animals; Calcium; Cell Membrane; Cyclic GMP; Humans; Hydralazine; Muscle Contraction; Muscle Protein

1984
Calcium, drug action and hypertension.
    Pharmacology & therapeutics, 1983, Volume: 22, Issue:2

    Topics: Animals; Arteries; Calcium; Chelating Agents; Humans; Hydralazine; Hypertension; Lanthanum; Muscle C

1983

Trials

1 trial available for hydralazine and Muscle Contraction

ArticleYear
Long-term inhibition of angiotensin converting enzyme suppresses calcium channel agonist-induced contraction of aorta in hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 14, Issue:6

    Topics: Animals; Aorta; Blood Pressure; Calcium Channel Agonists; Calcium Chloride; Dose-Response Relationsh

1989

Other Studies

56 other studies available for hydralazine and Muscle Contraction

ArticleYear
Synthesis of some potential antihypertensive phthalazinyl- and quinoxalinylguanidines.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:7

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Chemical Phenomena;

1982
Synthesis and antihypertensive activity of substituted trans-4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ols.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:11

    Topics: Animals; Antihypertensive Agents; Benzopyrans; Biological Assay; Hypertension; Indicators and Reagen

1983
Dual NEP/ECE inhibition improves endothelial function in mesenteric resistance arteries of 32-week-old SHR.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2017, Volume: 40, Issue:8

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzazepines; Bosentan; Endothelin-Converting Enzy

2017
The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Dopamine; Dose-Response Relation

2003
Effects of hydrazine derivatives on vascular smooth muscle contractility, blood pressure and cGMP production in rats: comparison with hydralazine.
    Vascular pharmacology, 2003, Volume: 40, Issue:1

    Topics: Animals; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Hydralazine; Hydrazines; Male

2003
Effect of isosorbide and hydralazine in painful primary esophageal motility disorders.
    Gastroenterology, 1982, Volume: 83, Issue:2

    Topics: Adult; Aged; Bethanechol; Bethanechol Compounds; Deglutition Disorders; Esophageal Diseases; Esophag

1982
Mechanism of action of hydralazine on vascular smooth muscle.
    Biochemical pharmacology, 1984, Sep-15, Volume: 33, Issue:18

    Topics: Actomyosin; Adenosine Triphosphatases; Animals; Calcium; Cattle; Enzyme Activation; Hydralazine; Mus

1984
Effects of hydralazine and verapamil on phosphorylase activity and guanosine cyclic 3',5'-monophosphate levels in guinea-pig taenia coli.
    British journal of pharmacology, 1980, Volume: 68, Issue:2

    Topics: Animals; Calcium; Colon; Cyclic GMP; Female; Guinea Pigs; Hydralazine; In Vitro Techniques; Muscle C

1980
Similarities between cytomegalovirus-induced cell rounding and contraction of smooth muscle cells.
    Life sciences, 1983, May-09, Volume: 32, Issue:19

    Topics: Cytomegalovirus; Cytomegalovirus Infections; Cytopathogenic Effect, Viral; Diazoxide; Fibroblasts; H

1983
Effect of hydralazine on nutritive flow to working canine gracilis skeletal muscle.
    Journal of the American College of Cardiology, 1984, Volume: 4, Issue:3

    Topics: Animals; Dogs; Hydralazine; In Vitro Techniques; Lactates; Muscle Contraction; Muscles; Oxygen; Oxyg

1984
Effect of hydralazine on tension and membrane potential in the rat caudal artery.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Animals; Arteries; Hydralazine; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle

1983
The effects of calcium channel inhibitors and other procedures affecting calcium translocation on drug-induced rhythmic contractions in the rat vas deferens.
    British journal of pharmacology, 1983, Volume: 79, Issue:2

    Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Hydralazine; In Vitro Techniques; Magnesium; Mal

1983
Favorable effects of hydralazine on the hemodynamic response to isometric exercise in chronic severe aortic regurgitation.
    The American journal of cardiology, 1984, Jun-01, Volume: 53, Issue:11

    Topics: Adult; Aged; Aortic Valve Insufficiency; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; H

1984
Differential effects of hydralazine on the biphasic responses of helical strips from rat tail arteries.
    General pharmacology, 1983, Volume: 14, Issue:1

    Topics: Animals; Arteries; Calcium; Cell Membrane; Hydralazine; In Vitro Techniques; Muscle Contraction; Mus

1983
In vitro differences between human arteries and veins in their responses to hydralazine.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:1

    Topics: Arteries; Calcium; Humans; Hydralazine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vas

1981
Dual influence of hydralazine on constrictor response to noradrenaline in isolated arterial smooth muscle.
    Canadian journal of physiology and pharmacology, 1981, Volume: 59, Issue:11

    Topics: Animals; Arteries; Electric Stimulation; Female; Guanethidine; Hydralazine; Magnesium; Male; Muscle

1981
Effects of hydralazine and D-600 on KCl induced contraction and phosphorylase activation in rabbit aorta.
    Proceedings of the Western Pharmacology Society, 1980, Volume: 23

    Topics: Animals; Aorta; Drug Interactions; Enzyme Activation; Gallopamil; Hydralazine; In Vitro Techniques;

1980
Hydralazine prevents changes in the contractile response of aortic but not portal vein strips in hypertensive rats.
    Blood vessels, 1980, Volume: 17, Issue:6

    Topics: Animals; Aorta; Blood Pressure; Desoxycorticosterone; Hydralazine; Hypertension; In Vitro Techniques

1980
Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Interaction between hydralazine and nitrovasodilators in vascular smooth muscle.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:3

    Topics: Animals; Aorta, Thoracic; Drug Interactions; Drug Tolerance; Hydralazine; In Vitro Techniques; Isoni

1993
Effects of hydralazine on contractile responses to alpha 1 and alpha 2-adrenoceptor agonists in isolated rubbed rat aorta.
    General pharmacology, 1994, Volume: 25, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Drug Interactions; Endothelium, Vascular; Femal

1994
Effect of chronic blood pressure reduction on soleus muscle contractile properties in spontaneously hypertensive rats.
    The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 2

    Topics: Amlodipine; Animals; Blood Pressure; Hindlimb; Hydralazine; Male; Muscle Contraction; Rats; Rats, In

1994
Pharmacological study of several effects of hydralazine in the bisected rat vas deferens.
    European journal of pharmacology, 1994, Jan-04, Volume: 251, Issue:1

    Topics: Animals; Calcium; Calcium Chloride; Calcium Radioisotopes; Cocaine; Hydralazine; In Vitro Techniques

1994
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:3

    Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; B

1995
Inhibition of calcium influx and tonic response to K+ of intestinal smooth muscle by hydralazine.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:3

    Topics: Animals; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response

1996
Blood pressure and age-dependent changes of endothelium-dependent tension oscillations in different strains of spontaneously hypertensive rats.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1996, Volume: 32, Issue:4

    Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Endotheliu

1996
Effects of hydralazine on responses to histamine and caffeine in ileal longitudinal muscle and taenia coli of the guinea pig.
    General pharmacology, 1997, Volume: 28, Issue:3

    Topics: Animals; Caffeine; Calcium; Calcium Channels; Colon; Guinea Pigs; Histamine; Hydralazine; Ileum; In

1997
Pyridazine derivatives XIV. Study of the vasorelaxant action of 6-aryl-5-piperidino-3-hydrazinopyridazines in isolated rat thoracic aorta: comparison with hydralazine.
    General pharmacology, 1998, Volume: 30, Issue:2

    Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Hydralazine; In Vitro Techniques; Male; Muscle Contract

1998
The alterations of vascular smooth muscle reactivity in vitro by human chorionic gonadotrophin.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1998, Volume: 198, Issue:4

    Topics: Acetylcholine; Animals; Blood Pressure; Chorionic Gonadotropin; Estradiol; Female; Hydralazine; In V

1998
Increases in cyclic GMP levels may not mediate relaxant effects of sodium nitroprusside, verapamil and hydralazine in rat vas deferens.
    Nature, 1978, Feb-02, Volume: 271, Issue:5644

    Topics: Animals; Cyclic GMP; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nit

1978
Relationship between cyclic nucleotide levels and drug-induced relaxation of smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 211, Issue:3

    Topics: Animals; Cyclic AMP; Cyclic GMP; Diazoxide; Drug Interactions; Female; Guinea Pigs; Hydralazine; In

1979
[Inhibition of cyclic AMP phosphodiesterase activity by ecarazine hydrochloride, hydralazine and their metabolites (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1979, Volume: 99, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Guinea Pigs; Hydralazine; Hydrazines; In Vitro Techniq

1979
Comparison of the in vitro effects of prazosin, nifedipine, and dihydralazine in isolated human mesenteric and crural vessels.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 241, Issue:2

    Topics: Adolescent; Adult; Aged; Calcium; Dihydralazine; Humans; Hydralazine; In Vitro Techniques; Leg; Mese

1979
Comparative evaluation of the in vitro effects of hydralazine and hydralazine acetonide on arterial smooth muscle.
    British journal of pharmacology, 1977, Volume: 61, Issue:3

    Topics: Animals; Aorta; Blood Vessels; Drug Interactions; Hydralazine; In Vitro Techniques; Muscle Contracti

1977
Mechanism of action of hydralazine and ISF 2123 on arterial smooth muscle [proceedings].
    British journal of pharmacology, 1978, Volume: 62, Issue:3

    Topics: Animals; Arteries; Hydralazine; Hydrazines; In Vitro Techniques; Male; Muscle Contraction; Muscle, S

1978
Interaction of hydralazine and hydrazone derivatives with contractile mechanisms in rabbit aortic smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 205, Issue:2

    Topics: Animals; Aorta, Thoracic; Blood Vessels; Calcium; Depression, Chemical; Drug Interactions; Hydralazi

1978
Identification of hydrallazine and hydrallazine hydrazone metabolites in human body fluids and quantitative in vitro comparisons of their smooth muscle relaxant activity.
    British journal of clinical pharmacology, 1978, Volume: 5, Issue:6

    Topics: Animals; Aorta; Humans; Hydralazine; Hydrazones; In Vitro Techniques; Mass Spectrometry; Muscle Cont

1978
Relationship between the direct inhibitory effect of hydralazine and propildazine on arterial smooth muscle contractility and sympathetic innervation.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 207, Issue:2

    Topics: Animals; Arteries; Dose-Response Relationship, Drug; Hydralazine; Hydrazines; In Vitro Techniques; M

1978
Pharmacology of budralazine, a new antihypertensive drug.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 235, Issue:1

    Topics: Animals; Antihypertensive Agents; Dogs; Female; Heart Rate; Hydralazine; Hypertension; Male; Methyld

1978
Study of in vitro effects of hydralazine metabolites--comparative evaluation of products of hydroxylation, hydrolysis and conjugation.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 235, Issue:1

    Topics: Animals; Hydralazine; Hydrolysis; Hydroxylation; In Vitro Techniques; Muscle Contraction; Muscle, Sm

1978
Subcellular distribution of hydralazine in rat single vascular muscle cells.
    Cell biology international reports, 1992, Volume: 16, Issue:10

    Topics: Animals; Aorta; Cells, Cultured; Hydralazine; Microscopy, Electron; Muscle Contraction; Muscle, Smoo

1992
Comparison of the effects of hydralazine and nifedipine on contractions and 45Ca influx of rat aorta.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:5

    Topics: Animals; Calcium Radioisotopes; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Muscle,

1991
A study on the hypotensive mechanism of pinacidil: relationship between its vasodilating effect and intracellular Ca2+ levels.
    Japanese journal of pharmacology, 1989, Volume: 49, Issue:2

    Topics: Animals; Antihypertensive Agents; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug;

1989
Calcium-force coupling mechanisms during vasodilator-induced relaxation of ferret aorta.
    The Journal of physiology, 1989, Volume: 412

    Topics: Animals; Aorta, Thoracic; Calcium; Carnivora; Colforsin; Ferrets; Hydralazine; In Vitro Techniques;

1989
Clinical pharmacology of vasodilator drugs.
    The Medical journal of Australia, 1985, Apr-01, Volume: 142, Issue:7

    Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Coronary Disease; Humans; Hydralazine; Hyper

1985
Ouabain-induced contraction of vascular smooth muscle in spontaneously hypertensive rats and the effect of hydralazine.
    European journal of pharmacology, 1988, Jul-14, Volume: 151, Issue:3

    Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium; Calcium Radioisotopes; Hydralazine; Hypertensi

1988
Comparison of nitroprusside and hydralazine in isolated uterine arteries from pregnant and nonpregnant patients.
    Anesthesiology, 1988, Volume: 68, Issue:4

    Topics: Arteries; Female; Ferricyanides; Humans; Hydralazine; In Vitro Techniques; Muscle Contraction; Muscl

1988
Effects of cadralazine on contractions induced by norepinephrine, serotonin, angiotensin II and K+ in rabbit aortic and renal arterial strips.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Hydralazine; In Vitro Techniques; Male; Muscle Contractio

1988
Effects of cadralazine on contractions induced by Ca2+ and norepinephrine in isolated rabbit aortic strips.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:3

    Topics: Animals; Aorta, Abdominal; Calcium; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Musc

1988
Mechanism of hydralazine-induced relaxation of arterial smooth muscle.
    Cardiovascular research, 1985, Volume: 19, Issue:7

    Topics: Animals; Barium; Barium Compounds; Calcium; Calcium Chloride; Chlorides; Dose-Response Relationship,

1985
Chronic treatment of rats with D-600 causes a compensatory decrease in the calcium requirement for contractility of vascular smooth and cardiac muscles.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:5

    Topics: Animals; Blood Pressure; Calcium; Gallopamil; Heart Rate; Hydralazine; In Vitro Techniques; Isoprote

1985
In vitro production and inhibition of aortic vasoconstriction by mercuric, cadmium, and other metal ions.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Cadmium; Cyanides; Edetic Acid; Epinephrine; Ethylmaleimid

1967
Effect of certain drugs on perfused human placenta. IX. Mode of action of angiotensin.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:5

    Topics: Angiotensin II; Blood Vessels; Constriction; Dipyridamole; Ethanolamines; Female; Humans; Hydralazin

1969
Drug failure in reducing pressor effect of isometric handgrip stress test in hypertension.
    American heart journal, 1973, Volume: 86, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Electrocardiogra

1973
"Hantzsch-type" dihydropyridine hypotensive agents. 3.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:9

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Cats; Central Nervous System; De

1974
Myogenic tone in isolated perfused resistance vessels from rats.
    The American journal of physiology, 1969, Volume: 216, Issue:6

    Topics: Animals; Blood Vessels; Calcium; Hydralazine; Jejunum; Male; Methods; Muscle Contraction; Muscle, Sm

1969