Page last updated: 2024-10-28

hydralazine and Mitral Incompetence

hydralazine has been researched along with Mitral Incompetence in 28 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Research Excerpts

ExcerptRelevanceReference
"Eleven dogs with mitral regurgitation and severe cough were given hydralazine for reduction of systemic arterial pressure."7.66Clinical experience with hydralazine for treatment of otherwise intractable cough in dogs with apparent left-side heart failure. ( Hamlin, RL; Kittleson, MD, 1982)
"Hydralazine is a smooth muscle relaxant and a potent arteriolar dilator."6.36Hydralazine in heart failure. ( Chatterjee, K, 1983)
"We evaluated long-term combined vasodilator therapy (hydralazine or ecarazine + isosorbide dinitrate) in 29 patients with chronic congestive heart failure resistant to the optimal conventional therapy."3.67Ambulatory long-term vasodilator therapy for chronic refractory heart failure: hemodynamic evaluation and clinical response. ( Hatano, M; Hibiya, K; Ichikawa, M; Nagasawa, M; Ozawa, Y; Saito, S; Tamura, Y; Tomobe, K; Yumikura, S, 1984)
"Eleven dogs with mitral regurgitation and severe cough were given hydralazine for reduction of systemic arterial pressure."3.66Clinical experience with hydralazine for treatment of otherwise intractable cough in dogs with apparent left-side heart failure. ( Hamlin, RL; Kittleson, MD, 1982)
"Hydralazine is a smooth muscle relaxant and a potent arteriolar dilator."2.36Hydralazine in heart failure. ( Chatterjee, K, 1983)
"The effect on myocardial function and structure of long-term administration of quinapril (10-20 mg daily), an angiotensin-converting-enzyme (ACE) inhibitor, was investigated in 24 patients (18 men, 6 women; mean age 48 [20-65] years) with chronic isolated asymptomatic aortic or mitral regurgitation."1.29[Long-term treatment with quinapril in chronic aortic and mitral insufficiency]. ( Schömig, A; Schön, HR, 1995)
"Furosemide was added after the 3-week examination, and at 6 months, dogs had received furosemide for at least 4 months."1.29Effects of long-term treatment with enalapril or hydralazine on the renin-angiotensin-aldosterone system and fluid balance in dogs with naturally acquired mitral valve regurgitation. ( Häggström, J; Hansson, K; Karlberg, BE; Kvart, C; Madej, A; Olsson, K, 1996)
"Atrial volumes and mitral and tricuspid regurgitation, in addition to left ventricular ejection fraction and indexes of left ventricular contractility (mean acceleration, ejection time and peak systolic pressure/end-systolic volume index), were measured using 2-dimensional and Doppler echocardiography and color flow imaging in 30 patients with advanced CHF, before and after acute vasodilator and diuretic therapy tailored to hemodynamic goals."1.28Acute reduction of atrial overload during vasodilator and diuretic therapy in advanced congestive heart failure. ( Child, JS; Hamilton, MA; Moriguchi, JD; Stevenson, LW; Woo, M, 1990)
"The severity of mitral regurgitation is, in part, determined by aortic impedance to left ventricular outflow."1.26Beneficial effects of hydralazine in severe mitral regurgitation. ( Botvinick, EH; Brundage, BH; Chatterjee, K; Greenberg, BH; Massie, BM; Parmley, WW, 1978)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199018 (64.29)18.7374
1990's8 (28.57)18.2507
2000's2 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levine, TB1
Levine, AB1
Bolenbaugh, J1
Green, PR1
Prasad, GV1
Vincent, L1
Hamilton, R1
Lim, K1
Beekman, RH1
Rocchini, AP1
Dick, M1
Crowley, DC1
Rosenthal, A1
Chatterjee, K4
Saito, S1
Ichikawa, M1
Ozawa, Y1
Yumikura, S1
Nagasawa, M1
Hibiya, K1
Tamura, Y1
Tomobe, K1
Hatano, M1
Sterz, H1
Greenberg, BH5
Rahimtoola, SH3
Cohn, JN1
Wagner, GC1
Robinson, PH1
Kittleson, MD4
Eyster, GE1
Olivier, NB1
Anderson, LK1
Rouleau, JL1
Massie, BM4
DeMots, H1
Murphy, E1
Hamlin, RL2
Schön, HR1
Schömig, A1
Roth, A1
Shotan, A1
Elkayam, U1
Häggström, J1
Hansson, K1
Karlberg, BE1
Kvart, C1
Madej, A1
Olsson, K1
Uehara, Y1
Takahashi, M1
Francoual, M1
Lellouche, D1
Castaigne, A1
Estampes, B1
Vernant, P1
Brundage, BH1
Botvinick, EH1
Parmley, WW1
Haeusslein, EA1
Zhilin, SV1
Vorob'ev, BI1
Kastanaian, AA1
Masalitinova, IV1
Lin, WW1
Chang, FJ1
Hwang, JF1
Tsai, ZH1
Lee, DY1
Chen, YT1
Hamilton, MA1
Stevenson, LW1
Child, JS1
Moriguchi, JD1
Woo, M1
Lavítola, Pde L1
de Moraes, AV1
Dallan, L1
Grinberg, M1
Sosa, EA1
Higa, SS1
Bessegato, L1
Pileggi, F1
Johnson, LE1
Oliver, NB1

Reviews

4 reviews available for hydralazine and Mitral Incompetence

ArticleYear
Hydralazine in heart failure.
    Herz, 1983, Volume: 8, Issue:4

    Topics: Animals; Aortic Valve Insufficiency; Cardiac Output; Cats; Coronary Circulation; Exercise Test; Hear

1983
Vasodilator therapy of congestive heart failure.
    Advances in internal medicine, 1980, Volume: 26

    Topics: Aortic Valve Insufficiency; Captopril; Dobutamine; Heart Failure; Humans; Hydralazine; Isosorbide Di

1980
Vasodilator therapy of pump failure complicating acute myocardial infarction.
    The Medical clinics of North America, 1979, Volume: 63, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output; Heart Arrest; Heart Rate; Hemodynamics; Humans; Hydralazine

1979
[Vasodilators: treatment of cardiac insufficiency].
    La Revue du praticien, 1977, Oct-21, Volume: 27, Issue:47

    Topics: Heart Failure; Humans; Hydralazine; Mitral Valve Insufficiency; Myocardial Infarction; Nitroglycerin

1977

Trials

3 trials available for hydralazine and Mitral Incompetence

ArticleYear
A randomized comparison between the hemodynamic effects of hydralazine and nitroglycerin alone and in combination at rest and during isometric exercise in patients with chronic mitral regurgitation.
    American heart journal, 1993, Volume: 125, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Chronic Disease; Drug Therapy, Combination; Exercise;

1993
[Differential use of peripheral vasodilators in the treatment of chronic circulatory failure in patients with mitral valve insufficiency].
    Kardiologiia, 1990, Volume: 30, Issue:3

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Heart Failure; Hemodynamics; Humans; Hydralazine;

1990
[Comparative study of vasodilator drugs in heart valve diseases].
    Arquivos brasileiros de cardiologia, 1987, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aortic Valve Insufficiency; Clinical Trials as Topic; Echocardiography; Female; H

1987

Other Studies

21 other studies available for hydralazine and Mitral Incompetence

ArticleYear
Reversal of heart failure remodeling: is it maintained?
    Clinical cardiology, 2003, Volume: 26, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiomyopathies; Echocardiography; Female

2003
Minimal change disease in association with fire coral (Millepora species) exposure.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 47, Issue:1

    Topics: Acute Kidney Injury; Animals; Anthozoa; Barbados; Bites and Stings; Combined Modality Therapy; Divin

2006
Vasodilator therapy in children: acute and chronic effects in children with left ventricular dysfunction or mitral regurgitation.
    Pediatrics, 1984, Volume: 73, Issue:1

    Topics: Adolescent; Captopril; Cardiac Catheterization; Child; Child, Preschool; Digoxin; Heart Failure; Hea

1984
Ambulatory long-term vasodilator therapy for chronic refractory heart failure: hemodynamic evaluation and clinical response.
    Japanese circulation journal, 1984, Volume: 48, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Cardiac Catheterization; Cardiomyopathy, Dilated; Chronic Disease; Dru

1984
[Causes of acute valve-conditioned left ventricular insufficiency-- attempt at a tabulated review].
    Wiener medizinische Wochenschrift (1946), 1984, Mar-15, Volume: 134, Issue:5

    Topics: Aortic Valve Insufficiency; Cardiac Glycosides; Dyspnea; Endocarditis, Bacterial; Humans; Hydralazin

1984
Usefulness of vasodilator therapy in acute and chronic valvular regurgitation.
    Current problems in cardiology, 1984, Volume: 9, Issue:4

    Topics: Aortic Valve; Aortic Valve Insufficiency; Combined Modality Therapy; Digoxin; Drug Therapy, Combinat

1984
The role of vasodilator therapy in the management of the patient with acute myocardial infarction.
    Primary care, 1981, Volume: 8, Issue:3

    Topics: Heart Failure; Heart Rupture; Hemodynamics; Humans; Hydralazine; Mitral Valve Insufficiency; Myocard

1981
Oral hydralazine therapy for chronic mitral regurgitation in the dog.
    Journal of the American Veterinary Medical Association, 1983, Jun-01, Volume: 182, Issue:11

    Topics: Administration, Oral; Animals; Cardiac Output; Chronic Disease; Dog Diseases; Dogs; Female; Heart Ra

1983
Hydralazine in chronic CHF.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 652

    Topics: Administration, Oral; Aortic Valve Insufficiency; Cardiac Output; Chronic Disease; Drug Therapy, Com

1981
Arterial dilators in mitral regurgitation: effects on rest and exercise hemodynamics and long-term clinical follow-up.
    Circulation, 1982, Volume: 65, Issue:1

    Topics: Aged; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Female; Follow-Up Studies; H

1982
Clinical experience with hydralazine for treatment of otherwise intractable cough in dogs with apparent left-side heart failure.
    Journal of the American Veterinary Medical Association, 1982, Jun-01, Volume: 180, Issue:11

    Topics: Animals; Blood Pressure; Cough; Dog Diseases; Dogs; Female; Heart Failure; Heart Rate; Hydralazine;

1982
Vasodilator therapy for valvular heart disease.
    JAMA, 1981, Jul-17, Volume: 246, Issue:3

    Topics: Aortic Valve Insufficiency; Cardiac Output, Low; Heart Valve Diseases; Hemodynamics; Humans; Hydrala

1981
Hydralazine Therapy for severe mitral regurgitation in a dog.
    Journal of the American Veterinary Medical Association, 1981, Nov-01, Volume: 179, Issue:9

    Topics: Animals; Cardiac Output; Cardiac Volume; Dog Diseases; Dogs; Hydralazine; Male; Mitral Valve Insuffi

1981
[Long-term treatment with quinapril in chronic aortic and mitral insufficiency].
    Deutsche medizinische Wochenschrift (1946), 1995, Mar-31, Volume: 120, Issue:13

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; Chronic Disease;

1995
Effects of long-term treatment with enalapril or hydralazine on the renin-angiotensin-aldosterone system and fluid balance in dogs with naturally acquired mitral valve regurgitation.
    American journal of veterinary research, 1996, Volume: 57, Issue:11

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Dog Dis

1996
Hemodynamic changes during administration of drugs for mitral regurgitation in dogs.
    The Journal of veterinary medical science, 1998, Volume: 60, Issue:2

    Topics: Animals; Captopril; Cardiotonic Agents; Digoxin; Dog Diseases; Dogs; Echocardiography, Doppler, Colo

1998
Beneficial effects of hydralazine in severe mitral regurgitation.
    Circulation, 1978, Volume: 58, Issue:2

    Topics: Adult; Aged; Arterioles; Blood Pressure; Cardiac Output; Coronary Vessels; Female; Heart Rate; Human

1978
Does the magnitude of mitral regurgitation determine hemodynamic response to vasodilation in chronic congestive heart failure?
    Chest, 1991, Volume: 100, Issue:5

    Topics: Adult; Aged; Chronic Disease; Heart Failure; Heart Valve Prosthesis; Hemodynamics; Humans; Hydralazi

1991
Hemodynamic effects of hydralazine in mitral valve prolapse with regurgitation.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1990, Volume: 46, Issue:5

    Topics: Adult; Aged; Female; Hemodynamics; Humans; Hydralazine; Male; Middle Aged; Mitral Valve Insufficienc

1990
Acute reduction of atrial overload during vasodilator and diuretic therapy in advanced congestive heart failure.
    The American journal of cardiology, 1990, May-15, Volume: 65, Issue:18

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Captopril; Diuretics; Drug Therapy, Combination; Female;

1990
Acute hemodynamic effects of hydralazine in dogs with chronic mitral regurgitation.
    Journal of the American Veterinary Medical Association, 1985, Aug-01, Volume: 187, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Dog Diseases; Dogs; Heart Failure; Hemodynamics; Hydralazin

1985