hydralazine has been researched along with Malignant Hypertension in 60 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to study the role of elastin in arteries with respect to hypertension and hypertensive arterial disease, aortic elastin content and elastase-like enzyme activity were examined and compared in stroke-prone spontaneously hypertensive rats (SHRSP), which show malignant hypertension, and Wistar-Kyoto normotensive rats (WKY)." | 7.67 | Elastin and elastase-like enzyme change in aorta of rat with malignant hypertension. ( Daniel, EE; Ito, H; Kwan, CY, 1987) |
| "We investigated the role of angiotensin II and endothelin-1 using the angiotensin AT1 receptor antagonist losartan and the endothelin ETA receptor antagonist atrasentan, in malignant hypertension and renal failure and damage induced by nitric oxide (NO) synthase inhibition in Harlan Sprague-Dawley (SD) rats." | 3.75 | Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat. ( Agharazii, M; Bélanger, S; Larivière, R; Lebel, M; Lemieux, P; Therrien, F, 2009) |
| "The blood pressure was decreased after chronic treatment with enalapril, MK-954, and hydralazine in deoxycorticosterone acetate (DOCA)-salt-induced malignant hypertension of spontaneously hypertensive rats (SHR); however, ventricular weight and plasma brain natriuretic peptide (BNP) concentration were decreased after enalapril and MK-954 but not after hydralazine." | 3.69 | Cardiac hypertrophy and brain natriuretic peptide in experimental hypertension. ( Fukui, T; Horio, T; Kohno, M; Kurihara, N; Takeda, T; Yasunari, K; Yokokawa, K; Yoshiyama, M, 1994) |
| "In order to study the role of elastin in arteries with respect to hypertension and hypertensive arterial disease, aortic elastin content and elastase-like enzyme activity were examined and compared in stroke-prone spontaneously hypertensive rats (SHRSP), which show malignant hypertension, and Wistar-Kyoto normotensive rats (WKY)." | 3.67 | Elastin and elastase-like enzyme change in aorta of rat with malignant hypertension. ( Daniel, EE; Ito, H; Kwan, CY, 1987) |
| "A 31-year-old woman developed bilateral posterior ischemic optic neuropathy and infarctions of the cerebral arterial border zones and spinal cord after correction of malignant hypertension." | 1.35 | Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension. ( An, SJ; Choi, JH; Choi, KD; Kim, HJ; Kim, JS; Lee, JE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (90.00) | 18.7374 |
| 1990's | 4 (6.67) | 18.2507 |
| 2000's | 2 (3.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, JH | 1 |
| Choi, KD | 1 |
| Kim, JS | 1 |
| Kim, HJ | 1 |
| Lee, JE | 1 |
| An, SJ | 1 |
| Therrien, F | 1 |
| Lemieux, P | 1 |
| Bélanger, S | 1 |
| Agharazii, M | 1 |
| Lebel, M | 1 |
| Larivière, R | 1 |
| ROQUE, JA | 1 |
| STURUP, H | 2 |
| GRUNER, A | 2 |
| FARMER, RG | 1 |
| GIFFORD, RW | 1 |
| HINES, EA | 1 |
| PERRY, HM | 1 |
| GILL, JR | 1 |
| GEORGE, JM | 1 |
| SOLOMON, A | 1 |
| BARTTER, FC | 1 |
| CHIRONE, E | 1 |
| Almazov, VA | 1 |
| Bondarenko, BB | 1 |
| Shabrov, AV | 1 |
| Vaziri, ND | 1 |
| Moyer, JH | 1 |
| Ram, CV | 1 |
| Grim, CE | 2 |
| Kohno, M | 2 |
| Fukui, T | 1 |
| Horio, T | 1 |
| Yokokawa, K | 2 |
| Yasunari, K | 2 |
| Yoshiyama, M | 1 |
| Kurihara, N | 1 |
| Takeda, T | 1 |
| Kano, H | 1 |
| Minami, M | 1 |
| Ueda, M | 1 |
| Tatsumi, Y | 1 |
| Yoshikawa, J | 1 |
| Moorthy, AV | 1 |
| Wu, MJ | 1 |
| Beirne, GJ | 1 |
| Sundstrom, WS | 1 |
| Markenson, JA | 1 |
| Sherman, RL | 1 |
| Kissin, MW | 1 |
| Williamson, RC | 1 |
| Woods, JW | 2 |
| Mitnick, PD | 1 |
| Feig, PU | 1 |
| Fleischmann, LE | 1 |
| Mroczek, WJ | 1 |
| Brodwall, EK | 1 |
| Flatmark, A | 1 |
| Diethelm, AG | 1 |
| Hartley, MW | 1 |
| Aldrete, JS | 1 |
| Sterling, WA | 1 |
| Morgan, JM | 1 |
| Okamoto, K | 2 |
| Ohta, Y | 2 |
| Chikugo, T | 2 |
| Shiokawa, H | 2 |
| Morita, N | 2 |
| Hamada, Y | 1 |
| Ferguson, RK | 1 |
| Vlasses, PH | 1 |
| Ito, H | 1 |
| Kwan, CY | 1 |
| Daniel, EE | 1 |
| Seedat, YK | 1 |
| Redgrave, JE | 1 |
| Swartz, SL | 1 |
| Burris, JF | 1 |
| Perret, C | 1 |
| Girardet, P | 1 |
| Philipp, T | 1 |
| Nast, HP | 1 |
| Mühlberg, H | 1 |
| Mühlberg, G | 1 |
| Mashaly, M | 1 |
| el-Ebrashy, N | 1 |
| Higazi, AM | 1 |
| el-Din Moustafa, S | 1 |
| Abul-Einen, M | 1 |
| Finnerty, FA | 2 |
| Tuckman, J | 1 |
| Messerli, F | 1 |
| Hodler, J | 1 |
| Zimmerman, SW | 1 |
| Bergin, JJ | 1 |
| Siegler, RL | 1 |
| Acchiardo, SR | 1 |
| Black, WD | 1 |
| Britt, L | 1 |
| McKeown, JW | 1 |
| Johnson, JG | 1 |
| Hatch, F | 1 |
| Fillastre, JP | 1 |
| Malandain, M | 1 |
| Gray, H | 1 |
| Dubois, D | 1 |
| Kim, KE | 1 |
| Onesti, G | 1 |
| Swartz, C | 1 |
| Freis, ED | 1 |
| Ahearn, DJ | 1 |
| Gittes, RF | 1 |
| McLaughlin, AP | 1 |
| Blythe, WB | 1 |
| Huffines, WD | 1 |
| Tucker, RM | 1 |
| Hunt, JC | 1 |
| Moser, M | 1 |
| Bock, KD | 1 |
| Mattern, WD | 1 |
| Sommers, SC | 1 |
| Kassirer, JP | 1 |
| Sevitt, LH | 1 |
| Evans, DJ | 1 |
| Wrong, OM | 1 |
| McAllister, RG | 1 |
| Van Way, CW | 1 |
| Dayani, K | 1 |
| Anderson, WJ | 1 |
| Temple, E | 1 |
| Michelakis, AM | 1 |
| Coppage, WS | 1 |
| Oates, JA | 1 |
| Bernsmeier, A | 1 |
| Pavesi, V | 1 |
| Campus, G | 1 |
| Pomerantz, HZ | 1 |
| Repetto, S | 1 |
| Rezzonico, A | 1 |
| Gervasini, N | 1 |
9 reviews available for hydralazine and Malignant Hypertension
| Article | Year |
|---|---|
[MALIGNANT HYPERTENSION].
Topics: Adrenalectomy; Angiotensins; Bretylium Compounds; Chlorisondamine; Diagnosis; Diet, Sodium-Restricte | 1964 |
[Mechanism of development and principles of treatment of malignant arterial hypertension].
Topics: Adrenergic beta-Antagonists; Anemia, Hemolytic; Animals; Antihypertensive Agents; Cyclic AMP; Factor | 1983 |
Malignant or accelerated hypertension.
Topics: Blood Coagulation Disorders; Brain Diseases; Diazoxide; Glomerulosclerosis, Focal Segmental; Humans; | 1984 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazin | 1984 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
Hypertensive emergencies and urgencies.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; | 1986 |
[Treatment of the hypertensive crisis].
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Diaz | 1973 |
Recent advances in the medical and surgical treatment of hypertension.
Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni | 1968 |
Treatment of "hypertensive encephalopathy" (accelerated hypertension). II.
Topics: Antihypertensive Agents; Diazoxide; Glomerulonephritis; Guanethidine; Humans; Hydralazine; Hypertens | 1969 |
2 trials available for hydralazine and Malignant Hypertension
| Article | Year |
|---|---|
[Ambulant long-term treatment of arterial hypertension].
Topics: Animals; Antihypertensive Agents; Chlorothiazide; Clinical Trials as Topic; Diuretics; Female; Gangl | 1965 |
Treatment of hypertension with large doses of the beta-adrenergic blocking drug oxprenolol, alone, and in combination with the vasodilator dihydralazine.
Topics: Chlorothiazide; Clinical Trials as Topic; Drug Synergism; Furosemide; Heart Rate; Hydralazine; Hyper | 1973 |
49 other studies available for hydralazine and Malignant Hypertension
| Article | Year |
|---|---|
Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension.
Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain; Brain Stem Infarctions; C | 2008 |
Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrasenta | 2009 |
Hexamethonium and apresoline (L-hydrazinophthalazine) in the treatment of malignant hypertension; report of a case.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypertension, Malignant; Muscle Rel | 1954 |
[Combined medication over a long period in severe non-malignant hypertension].
Topics: Aged; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Muscle Relaxants, Central; Reserpi | 1957 |
Long-term combined drug therapy in non-malignant hypertension.
Topics: Cardiovascular Agents; Hydralazine; Hypertension; Hypertension, Malignant; Muscle Relaxants, Central | 1958 |
Effect of medical treatment of severe hypertension. A follow-up study of 161 patients with group 3 and group 4 hypertension.
Topics: Follow-Up Studies; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Hypertension, Maligna | 1963 |
CARCINOMA AND HYDRALAZINE TOXICITY IN PATIENTS WITH MALIGNANT HYPERTENSION.
Topics: Breast Neoplasms; Carcinoma; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Lung Neopla | 1963 |
HYPERALDOSTERONISM AND RENAL SODIUM LOSS REVERSED BY DRUG TREATMENT FOR MALIGNANT HYPERTENSION.
Topics: Blood Chemical Analysis; Chlorambucil; Guanethidine; Humans; Hydralazine; Hyperaldosteronism; Hypert | 1964 |
Management of malignant hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Drug | 1980 |
Cardiac hypertrophy and brain natriuretic peptide in experimental hypertension.
Topics: Animals; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Pressure; Blood Urea Nitrogen; Cardiom | 1994 |
Renoprotective effects of a combined endothelin type A/type B receptor antagonist in experimental malignant hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Endothelin Receptor Antagoni | 1997 |
Control of hypertension with acute renal failure in scleroderma without nephrectomy.
Topics: Acute Kidney Injury; Humans; Hydralazine; Hypertension, Malignant; Male; Middle Aged; Propranolol; R | 1978 |
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide | 1979 |
Hydrallazine-induced SLE-like syndrome presenting as a leg ulcer.
Topics: Humans; Hydralazine; Hypertension, Malignant; Leg Ulcer; Lupus Erythematosus, Systemic; Male; Middle | 1979 |
Malignant hypertension: clinical recognition and management.
Topics: Adult; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Kidney; Male; | 1978 |
Control of hypertension and reversal of renal failure in scleroderma.
Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Humans; Hydralazine; Hypertension, Malignant; M | 1978 |
Management of hypertensive crisis in children.
Topics: Acute Disease; Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Diazoxide; Humans; Hy | 1977 |
Malignant hypertension.
Topics: Diazoxide; Diuretics; Humans; Hydralazine; Hypertension, Malignant; Kidney; Nephrectomy; Nitroprussi | 1977 |
[Treatment of malignant hypertension].
Topics: Adolescent; Adult; Diazoxide; Humans; Hydralazine; Hypertension, Malignant; Male; Reserpine | 1976 |
Treatment of accelerated hypertension and end stage renal failure by bilateral nephrectomy and renal transplantation.
Topics: Acute Kidney Injury; Adult; Biopsy; Blood Pressure; Child; Creatinine; Female; Graft Rejection; Guan | 1975 |
Chronic treatment with captopril, SQ29,852, hydralazine and a 33% fish meal diet in malignant stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Captopril; Cerebrova | 1991 |
Therapy and prevention of hypertension of M-SHRSP.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cerebrovascular Disorders; Diet; Disea | 1991 |
Elastin and elastase-like enzyme change in aorta of rat with malignant hypertension.
Topics: Aging; Animals; Aorta; Blood Pressure; Cell Membrane; Elastin; Hydralazine; Hypertension, Malignant; | 1987 |
Patient with malignant hypertension alive after 25 years. A case report.
Topics: Adult; Chlorothiazide; Drug Therapy, Combination; Follow-Up Studies; Guanethidine; Humans; Hydralazi | 1986 |
Diagnosis and management of malignant hypertension.
Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Malignant; Kidney Function Tests | 1985 |
Hypertensive emergencies.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hyp | 1985 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; | 1974 |
Management of renal hypertension complicated by renal insufficiency.
Topics: Blood Urea Nitrogen; Chlorothiazide; Guanethidine; Humans; Hydralazine; Hypertension, Malignant; Met | 1967 |
Treatment of hypertensive crisis.
Topics: Adrenergic alpha-Antagonists; Diazoxide; Ethacrynic Acid; Ferricyanides; Furosemide; Humans; Hydrala | 1970 |
Dietary sodium restriction and natriuresis in management of hypertension.
Topics: Adult; Aged; Benzothiadiazines; Diet, Sodium-Restricted; Diuretics; Ethacrynic Acid; Female; Furosem | 1974 |
Aggressive drug therapy in accelerated hypertension.
Topics: Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Ferr | 1974 |
Heparin therapy for the renal disease of malignant hypertension.
Topics: Adult; Anemia, Hemolytic; Creatinine; Dipyridamole; Female; Guanethidine; Hematoma; Heparin; Humans; | 1974 |
Malignant hypertension in children; a patient treated with bilateral nephrectomy.
Topics: Blood Pressure; Child; Creatinine; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; H | 1974 |
Experience with hemodialysis and renal transplantation in patients with malignant hypertension.
Topics: Acute Kidney Injury; Adult; Brain Diseases; Diazoxide; Diet Therapy; Female; Follow-Up Studies; Furo | 1974 |
[Treatment of malignant nephroangiosclerosis with diazoxide].
Topics: Diazoxide; Glomerular Filtration Rate; Humans; Hydralazine; Hypertension, Malignant; Injections, Int | 1972 |
Problems in therapy for the hypertensive patient.
Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic | 1973 |
Hypertension: challenge in preventive medicine.
Topics: Aged; Aneurysm; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Drug Therap | 1973 |
Treatment of malignant hypertension with sodium nitroprusside.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Chemical Phenomena; Chemistry; Diazoxide; Drug Re | 1974 |
Unilateral operation for bilateral renovascular disease.
Topics: Arteriosclerosis; Endarterectomy; Humans; Hydralazine; Hypertension, Malignant; Hypertension, Renal; | 1974 |
Management of malignant hypertension complicated by renal insufficiency. A follow-up study.
Topics: Adult; Aged; Arteries; Autopsy; Benzothiadiazines; Diuretics; Drug Therapy, Combination; Female; Fol | 1974 |
Editorial: Malignant hypertension.
Topics: Blood Pressure; Cardiac Output; Diazoxide; Ferricyanides; Furosemide; Humans; Hydralazine; Hypertens | 1974 |
[What is reliable in the therapy of hypertension?].
Topics: Arteriosclerosis; Cerebral Hemorrhage; Diet, Reducing; Diet, Sodium-Restricted; Guanethidine; Health | 1970 |
Oliguric acute renal failure in malignant hypertension.
Topics: Acute Kidney Injury; Adult; Anuria; Blood Urea Nitrogen; Diagnosis, Differential; Female; Glomerulon | 1972 |
Acute oliguric renal failure due to accelerated (malignant) hypertension.
Topics: Acute Kidney Injury; Adolescent; Adult; Antihypertensive Agents; Anuria; Blood Urea Nitrogen; Diazox | 1971 |
Malignant hypertension: effect of therapy on renin and aldosterone.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Antihypertensive Agents; Blood | 1971 |
[Clinical picture and therapy of hypertension].
Topics: Adult; Aged; Blood Pressure; Diagnosis, Differential; Diet Therapy; Diet, Sodium-Restricted; Drug Sy | 1967 |
[Results of hypotensive treatment in a hospital environment].
Topics: Adult; Aged; Arteriosclerosis; Carbamates; Female; Humans; Hydralazine; Hydrochlorothiazide; Hyperte | 1968 |
Fourteen-year survival in a case of malignant hypertension under hypotensive drug therapy.
Topics: Adult; Antihypertensive Agents; Chlorothiazide; Guanethidine; Hexamethonium Compounds; Humans; Hydra | 1968 |
[Considerations on ambulatory therapy in a group of hypertensive patients].
Topics: Adult; Aged; Ambulatory Care; Carbamates; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothia | 1969 |