hydralazine has been researched along with Lupus Vulgaris in 14 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Lupus Vulgaris: A form of cutaneous tuberculosis. It is seen predominantly in women and typically involves the NASAL MUCOSA; BUCCAL MUCOSA; and conjunctival mucosa.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension." | 7.67 | Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report. ( Bar-Khayim, Y; Dgani, R; Lancet, M; Mogilner, BM; Nissim, F; Shoham, Z; Yemini, M, 1989) |
| " Current recommendations on hydralazine dosage are unsatisfactory for the 40% of hypertensive patients who are rapid acetylators." | 5.27 | Should the acetylator phenotype be determined when prescribing hydralazine for hypertension? ( Freestone, S; Ollerenshaw, JD; Phillips, FC; Ramsay, LE; Silas, JH; Tucker, GT, 1984) |
| " The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension." | 3.67 | Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report. ( Bar-Khayim, Y; Dgani, R; Lancet, M; Mogilner, BM; Nissim, F; Shoham, Z; Yemini, M, 1989) |
| " Current recommendations on hydralazine dosage are unsatisfactory for the 40% of hypertensive patients who are rapid acetylators." | 1.27 | Should the acetylator phenotype be determined when prescribing hydralazine for hypertension? ( Freestone, S; Ollerenshaw, JD; Phillips, FC; Ramsay, LE; Silas, JH; Tucker, GT, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suwa, A | 1 |
| Reidenberg, MM | 1 |
| Timbrell, JA | 1 |
| Facchini, V | 1 |
| Harland, SJ | 1 |
| Mansilla-Tinoco, R | 1 |
| Ramsay, LE | 1 |
| Silas, JH | 1 |
| Ollerenshaw, JD | 1 |
| Tucker, GT | 1 |
| Phillips, FC | 1 |
| Freestone, S | 1 |
| Sinclair, AJ | 1 |
| Warrington, SJ | 1 |
| Hofstra, AH | 2 |
| Yung, R | 1 |
| Chang, S | 1 |
| Hemati, N | 1 |
| Johnson, K | 1 |
| Richardson, B | 2 |
| Matassa, LC | 1 |
| Uetrecht, JP | 1 |
| Hess, EV | 1 |
| Burlingame, RW | 1 |
| Rubin, RL | 1 |
| Yemini, M | 1 |
| Shoham, Z | 1 |
| Dgani, R | 1 |
| Lancet, M | 1 |
| Mogilner, BM | 1 |
| Nissim, F | 1 |
| Bar-Khayim, Y | 1 |
| Cornacchia, E | 1 |
| Golbus, J | 1 |
| Maybaum, J | 1 |
| Strahler, J | 1 |
| Hanash, S | 1 |
| Beickert, A | 1 |
| Wiesenthal, F | 1 |
| Franow, KJ | 1 |
| McNay, JL | 1 |
3 reviews available for hydralazine and Lupus Vulgaris
| Article | Year |
|---|---|
[Immunologic tests: Anti-histone antibodies].
Topics: Antibodies, Antinuclear; Biomarkers; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Techniq | 2005 |
Metabolism of hydralazine: relevance to drug-induced lupus.
Topics: Animals; Humans; Hydralazine; Lupus Vulgaris | 1994 |
Drug-related lupus.
Topics: Antibodies, Antinuclear; Chlorpromazine; Drug Hypersensitivity; Eosinophilia-Myalgia Syndrome; Human | 1991 |
11 other studies available for hydralazine and Lupus Vulgaris
| Article | Year |
|---|---|
The chemical induction of systemic lupus erythematosus and lupus-like illnesses.
Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythemato | 1981 |
Hydralazine-induced lupus: is there a toxic metabolic pathway?
Topics: Acetylation; Biotransformation; Creatinine; Female; Humans; Hydralazine; Kinetics; Lupus Vulgaris; M | 1984 |
Should the acetylator phenotype be determined when prescribing hydralazine for hypertension?
Topics: Acetylation; Adult; Aged; Blood Pressure; Chemistry, Organic; Female; Humans; Hydralazine; Hypertens | 1984 |
Severe renal failure in hydralazine-induced lupus.
Topics: Acute Kidney Injury; Aged; Female; Humans; Hydralazine; Lupus Vulgaris | 1981 |
Mechanisms of drug-induced lupus. IV. Comparison of procainamide and hydralazine with analogs in vitro and in vivo.
Topics: Animals; Antibody Formation; Autoantibodies; Autoimmunity; DNA Methylation; Female; Gene Expression; | 1997 |
Metabolism of hydralazine by activated leukocytes: implications for hydralazine induced lupus.
Topics: Chromatography, High Pressure Liquid; Humans; Hydralazine; Leukocytes; Lupus Vulgaris; Mass Spectrom | 1991 |
Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin.
Topics: Autoantibodies; Chlorpromazine; Chromatin; DNA; Enzyme-Linked Immunosorbent Assay; Histones; Humans; | 1991 |
Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report.
Topics: Adult; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Lupus Vulgaris; Pregnancy; Pregna | 1989 |
Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity.
Topics: Autoimmune Diseases; DNA (Cytosine-5-)-Methyltransferases; Humans; Hydralazine; Immunosuppressive Ag | 1988 |
[Effect of hydralazine treatment on the LE phenomenon in NZB and A mice].
Topics: Animals; Disease Susceptibility; Female; Hydralazine; Lupus Vulgaris; Male; Mice; Neutrophils | 1970 |
Adrenolytic and vasodilator therapy.
Topics: Adrenergic beta-Antagonists; Benzyl Compounds; Blood Circulation; Cardiac Output; Clonidine; Diazoxi | 1974 |