hydralazine has been researched along with Libman-Sacks Disease in 261 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Following the publication of A-HeFT, an increase in the amount of hydralazine prescribed in patients with heart failure has been noted." | 8.83 | Hydralazine-induced lupus: maintaining vigilance with increased use in patients with heart failure. ( Finks, AL; Finks, SW; Self, TH, 2006) |
| "This is the second case report of hydralazine induced Sweet's syndrome and lupus erythematosus." | 8.78 | Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature. ( Franz, T; Medsger, TA; Ramsey-Goldman, R; Solano, FX, 1990) |
| "A 52-year-old Hispanic woman with a medical history of resistant hypertension treated with hydralazine 10 mg twice daily for 1 year presented with generalized weakness, dizziness, nausea, vomiting, and gross hematuria." | 8.31 | Overlapping drug-induced vasculitis, ANCA-associated vasculitis, and lupus nephritis caused by low-dose hydralazine. ( Agaronov, A; Akhondi, H; Bhatnagar, M; Pepito, D; Sarkisyan, E; Sotoudeh Deilamy, I, 2023) |
| "Hydralazine is an antihypertensive medication that has been associated with drug-induced lupus erythematosus (DIL) as well as ANCA-associated vasculitis (AAV)." | 7.88 | Hydralazine-associated vasculitis: Overlapping features of drug-induced lupus and vasculitis. ( Kumar, B; Lenert, P; Strouse, J; Suneja, M; Swee, M, 2018) |
| " The present study was aimed to investigate distribution of anti-lactoferrin antibodies in systemic lupus erythematosus, the hydralazine-induced SLE-like syndrome, and in rheumatoid arthritis compared to RA complicated with vasculitis." | 7.69 | Occurrence of anti-lactoferrin antibodies in patients with systemic lupus erythematosus, hydralazine-induced lupus, and rheumatoid arthritis. ( Hultquist, R; Nässberger, L; Sturfelt, G, 1994) |
| "A patient who developed pulmonary hypertension and systemic lupus erythematosus as a complication of hydralazine therapy is reported." | 7.67 | Pulmonary hypertension in hydralazine induced systemic lupus erythematosus: association with C4 null allele. ( Asherson, RA; Benbow, AG; Hughes, GR; Jackson, N; Speirs, CJ, 1986) |
| " Immune complex glomerulonephritis has been demonstrated in a few cases of SLE following procainamide or anticonvulsant therapy but has not been documented in association with hydralazine-induced SLE despite the recognition of this syndrome 30 years ago." | 7.67 | Immune complex glomerulonephritis in hydralazine-induced SLE. ( Harrington, JT; Levey, AS; Pinn, VW; Shapiro, KS, 1984) |
| "A 48-year-old white woman who for 3 years had been taking hydralazine, 100 mg three times a day, propranolol, 160 mg twice a day, and chlorothiazide, 500 mg/day, for hypertension suddenly developed rapidly expanding ulcers that looked like pyoderma gangrenosum." | 7.67 | Hydralazine-induced systemic lupus erythematosus presenting as pyoderma gangrenosum-like ulcers. ( Peterson, LL, 1984) |
| " Hoarseness developed in a 60-year-old man that was secondary to ulcerated lesions, which involved the epiglottis and aryteno-epiglottic folds, with serologic evidence of SLE after he had been treated with hydralazine for six months." | 7.67 | Hydralazine hoarseness. A new appearance of drug-induced systemic lupus erythematosus. ( Forouhar, FA; Weiser, GA; White, WB, 1984) |
| "A reversible syndrome resembling systemic lupus erythematosus and induced by hydralazine hydrochloride therapy is a well-recognized phenomenon in adults but does not seem to have been reported in children." | 7.65 | Hydralazine-induced lupus erythematosus-like syndrome. ( Irias, JJ, 1975) |
| "Following the publication of A-HeFT, an increase in the amount of hydralazine prescribed in patients with heart failure has been noted." | 4.83 | Hydralazine-induced lupus: maintaining vigilance with increased use in patients with heart failure. ( Finks, AL; Finks, SW; Self, TH, 2006) |
| "This is the second case report of hydralazine induced Sweet's syndrome and lupus erythematosus." | 4.78 | Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature. ( Franz, T; Medsger, TA; Ramsey-Goldman, R; Solano, FX, 1990) |
| " Some of this information includes: the unexpected yet very real hazards as well as benefits associated with the long-term use of powerful drugs, in particular the original description of hydralazine-induced lupus, its relation to genetic markers and its association with control of hypertension; the apparently decreasing need for antihypertensive drugs in subjects with well-controlled severe and moderate hypertension; the identification of risk factors for the complications of hypertension and the quantitation of their effects; the decrease in the incidence of hypertensive complications associated with the pharmacologic treatment of severe, moderate and, at least, the upper ranges of mild hypertension; the possibility of designing a chemical to block a specific reaction and the realization that it would have broader than expected effects; and the primary prevention of myocardial infarction in very high risk subjects." | 4.77 | The evolution of antihypertensive therapy. ( Perry, HM, 1985) |
| "A 52-year-old Hispanic woman with a medical history of resistant hypertension treated with hydralazine 10 mg twice daily for 1 year presented with generalized weakness, dizziness, nausea, vomiting, and gross hematuria." | 4.31 | Overlapping drug-induced vasculitis, ANCA-associated vasculitis, and lupus nephritis caused by low-dose hydralazine. ( Agaronov, A; Akhondi, H; Bhatnagar, M; Pepito, D; Sarkisyan, E; Sotoudeh Deilamy, I, 2023) |
| "Hydralazine is an antihypertensive medication that has been associated with drug-induced lupus erythematosus (DIL) as well as ANCA-associated vasculitis (AAV)." | 3.88 | Hydralazine-associated vasculitis: Overlapping features of drug-induced lupus and vasculitis. ( Kumar, B; Lenert, P; Strouse, J; Suneja, M; Swee, M, 2018) |
| " The present study was aimed to investigate distribution of anti-lactoferrin antibodies in systemic lupus erythematosus, the hydralazine-induced SLE-like syndrome, and in rheumatoid arthritis compared to RA complicated with vasculitis." | 3.69 | Occurrence of anti-lactoferrin antibodies in patients with systemic lupus erythematosus, hydralazine-induced lupus, and rheumatoid arthritis. ( Hultquist, R; Nässberger, L; Sturfelt, G, 1994) |
| "A patient who developed pulmonary hypertension and systemic lupus erythematosus as a complication of hydralazine therapy is reported." | 3.67 | Pulmonary hypertension in hydralazine induced systemic lupus erythematosus: association with C4 null allele. ( Asherson, RA; Benbow, AG; Hughes, GR; Jackson, N; Speirs, CJ, 1986) |
| "Respiratory stridor and hoarseness were the predominant presenting symptoms in a 63-year-old woman with an hydralazine induced lupus syndrome." | 3.67 | Laryngeal manifestations of drug induced lupus. ( Maxwell, D; Silver, R, 1987) |
| " Immune complex glomerulonephritis has been demonstrated in a few cases of SLE following procainamide or anticonvulsant therapy but has not been documented in association with hydralazine-induced SLE despite the recognition of this syndrome 30 years ago." | 3.67 | Immune complex glomerulonephritis in hydralazine-induced SLE. ( Harrington, JT; Levey, AS; Pinn, VW; Shapiro, KS, 1984) |
| "A 48-year-old white woman who for 3 years had been taking hydralazine, 100 mg three times a day, propranolol, 160 mg twice a day, and chlorothiazide, 500 mg/day, for hypertension suddenly developed rapidly expanding ulcers that looked like pyoderma gangrenosum." | 3.67 | Hydralazine-induced systemic lupus erythematosus presenting as pyoderma gangrenosum-like ulcers. ( Peterson, LL, 1984) |
| " Hoarseness developed in a 60-year-old man that was secondary to ulcerated lesions, which involved the epiglottis and aryteno-epiglottic folds, with serologic evidence of SLE after he had been treated with hydralazine for six months." | 3.67 | Hydralazine hoarseness. A new appearance of drug-induced systemic lupus erythematosus. ( Forouhar, FA; Weiser, GA; White, WB, 1984) |
| "The immunological side-effects under treatment with antihypertensive drugs are mainly limited to autoimmunity and autoimmune disease caused by alpha-methyldopa and hydralazine." | 3.66 | Immunological side-effects of antihypertensive drugs. ( Holm, G, 1979) |
| "An 82-year-old woman developed symptomatic reactive hypoglycemia in the same year she developed a lupus-like syndrome, probably secondary to the administration of procainamide or hydralazine." | 3.66 | Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosus. ( Blackshear, PJ; Kahn, CR; Kriauciunas, KA; Rotner, HE, 1983) |
| "A reversible syndrome resembling systemic lupus erythematosus and induced by hydralazine hydrochloride therapy is a well-recognized phenomenon in adults but does not seem to have been reported in children." | 3.65 | Hydralazine-induced lupus erythematosus-like syndrome. ( Irias, JJ, 1975) |
| "Hydralazine has been known to cause a lupus-like syndrome that can produce the clinical manifestations of SLE." | 2.40 | Hydralazine-induced lupus and vocal fold paralysis. ( Clayton, MI; Hari, CK; Raza, SA, 1998) |
| "Two patients with bullous systemic lupus erythematosus are reported." | 2.38 | Bullous systemic lupus erythematosus. ( Benedetto, EA; Bergfeld, WF; Fleming, MG; Norris, M; Tomecki, KJ; Tuthill, RJ; Weber, LA, 1989) |
| "Further study of drug-induced systemic lupus erythematosus is necessary in order to resolve these problems regarding pathogenesis." | 2.36 | Drug-induced systemic lupus erythematosus. ( Weinstein, A, 1980) |
| "Hydralazine hydrochloride was orally administered in a concentration of 25 mg/kg to the five mice groups once weekly for a period of 5 weeks to induce a lupus-like condition." | 1.91 | In vivo ameliorative effects of vitamin E against hydralazine-induced lupus. ( Githaiga, FM; Ngugi, MP; Omwenga, GI, 2023) |
| "We analysed all ICSRs classified as 'systemic lupus erythematosus' according to the Medical Dictionary for Drug Regulatory Activities term (preferred term level) in VigiBase." | 1.51 | Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database. ( Arnaud, L; Chasset, F; Gavand, PE; Lambert, A; Lebrun-Vignes, B; Martin, T; Mertz, P; Muller, C; Salem, JE; Sibilia, J; Tebacher-Alt, M, 2019) |
| "Procainamide is a competitive DNA methyltransferase (Dnmt) inhibitor, hydralazine inhibits ERK pathway signaling thereby decreasing Dnmt expression, and in lupus T cells decreased ERK pathway signaling causing a similar Dnmt decrease." | 1.33 | Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. ( Lu, Q; Richardson, BC; Wu, A, 2005) |
| " The DIL-causing potential of each chemical group is a measurable intrinsic characteristic of that group, and the probability of DIL appearance is directly proportional to the total dosage of the drug in question." | 1.32 | A predictive equation for drug-induced lupus. ( Adhami, E, 2003) |
| "Hydralazine was stopped and the patient gradually became asymptomatic." | 1.29 | Effect of acute cytomegalovirus infection on drug-induced SLE. ( Geltner, D; Schattner, A; Sthoeger, Z, 1994) |
| "21 patients with systemic lupus erythematosus induced by long-term treatment with hydralazine were investigated to see whether susceptibility to this syndrome was associated with deficiency of the classical pathway complement protein, C4." | 1.28 | Complement system protein C4 and susceptibility to hydralazine-induced systemic lupus erythematosus. ( Batchelor, JR; Chapel, H; Davey, NJ; Fielder, AH; Speirs, C, 1989) |
| "Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases." | 1.27 | [Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. ( Wollina, U, 1984) |
| "Hydralazine is an effective antihypertensive drug that has come to be used in restricted dosage (not more than 200 mg daily) because of its risk of inducing the lupus syndrome." | 1.27 | The lupus syndrome induced by hydralazine: a common complication with low dose treatment. ( Cameron, HA; Ramsay, LE, 1984) |
| "Six women with hypertension are described who developed an immune complex glomerulonephritis after taking 50-300 mg hydralazine daily for 6 months to 7 years." | 1.27 | Hydralazine and lupus nephritis. ( Dowling, JP; Ihle, BU; Kincaid-Smith, P; Whitworth, JA, 1984) |
| "The syndrome resembling systemic lupus erythematosus (SLE) associated with long-term treatment with hydralazine and isoniazid seems to be due to the drugs themselves rather than their metabolites." | 1.27 | Drugs that induce systemic lupus erythematosus inhibit complement component C4. ( Gill, EW; Sim, E; Sim, RB, 1984) |
| "A 23-year-old woman with systemic lupus erythematosus was found to have severe pulmonary hypertension with secondary patency of the foramen ovale." | 1.27 | Danger of vasodilator therapy for pulmonary hypertension in patent foramen ovale. ( Girard, P; Laine, JF; Motté, G; Petitpretz, P; Slama, M, 1986) |
| "Five drugs associated with systemic lupus erythematosus were studied for their effect on the salt-induced right-handed (B) to left-handed (Z) transition of poly(dG-me5dC) X poly(dG-me5dC)." | 1.27 | Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA. ( Messner, RP; Thomas, TJ, 1986) |
| "Drugs which induce systemic lupus erythematosus as a toxic side effect have been shown to inhibit the covalent binding of C4, which is an important event in immune complex clearance in normal individuals." | 1.27 | Interaction of nucleophilic compounds with complement component C4. ( Jones, A; Parker, KE; Sim, E; Wood, M, 1988) |
| "Hydralazine was shown to interact with a soluble DNA-histone complex, and the resulting interaction rendered the histone moiety resistant to trypsin digestion." | 1.26 | The role of histones as nuclear autoantigens in drug-related lupus erythematosus. ( Portanova, JP; Tan, EM, 1981) |
| "Hydralazine treatment did not alter cell-mediated immune responses." | 1.26 | Prospective study of immunologic effects of hydralazine in hypertensive patients. ( Adams, LE; Foad, B; Hess, EV; Litwin, A; Loggie, JH; Zimmer, H, 1981) |
| " It was found that long-term administration of hydralazine caused a decrease of erythrocyte count, a decrease of haemoglobin concentration and a decrease of haemoglobin content in individual red blood cell as well as a decrease of a single erythrocyte volume." | 1.26 | Haematological changes in experimental hydralazine-induced collagen-like syndrome in guinea pigs. ( Dróźdź, M; Kucharz, E, 1978) |
| "Hydralazine treatment did not alter cell-mediated immune responses and hydralazine antibodies were not detected." | 1.26 | Immunologic effects of hydralazine in hypertensive patients. ( Adams, LE; Hess, EV; Litwin, A; Zimmer, H, 1981) |
| "26 patients with systemic lupus erythematosus (SLE) induced by treatment with the antihypertensive drug hydralazine were investigated to determine if predisposition to the toxic effect was associated with an HLA-DR antigen." | 1.26 | Hydralazine-induced systemic lupus erythematosus: influence of HLA-DR and sex on susceptibility. ( Aber, GM; Batchelor, JR; Bernstein, R; Bing, RF; Dollery, CT; Hughes, GR; Naish, PF; Russell, GI; Ryan, P; Tinoco, RM; Welsh, KI, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 208 (79.69) | 18.7374 |
| 1990's | 23 (8.81) | 18.2507 |
| 2000's | 17 (6.51) | 29.6817 |
| 2010's | 9 (3.45) | 24.3611 |
| 2020's | 4 (1.53) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatnagar, M | 1 |
| Agaronov, A | 1 |
| Sarkisyan, E | 1 |
| Sotoudeh Deilamy, I | 1 |
| Pepito, D | 1 |
| Akhondi, H | 1 |
| Githaiga, FM | 1 |
| Omwenga, GI | 1 |
| Ngugi, MP | 1 |
| Rubin, RL | 5 |
| Haluptzok, RF | 1 |
| Davila, LM | 1 |
| Kumar, B | 1 |
| Strouse, J | 1 |
| Swee, M | 1 |
| Lenert, P | 1 |
| Suneja, M | 1 |
| He, Y | 1 |
| Sawalha, AH | 2 |
| Arnaud, L | 1 |
| Mertz, P | 1 |
| Gavand, PE | 1 |
| Martin, T | 1 |
| Chasset, F | 1 |
| Tebacher-Alt, M | 1 |
| Lambert, A | 1 |
| Muller, C | 1 |
| Sibilia, J | 1 |
| Lebrun-Vignes, B | 1 |
| Salem, JE | 1 |
| Pan, Q | 1 |
| Guo, Y | 1 |
| Guo, L | 1 |
| Liao, S | 1 |
| Zhao, C | 1 |
| Wang, S | 1 |
| Liu, HF | 1 |
| Chamsi-Pasha, MA | 1 |
| Bassiouny, M | 1 |
| Kim, ES | 1 |
| Vedove, CD | 1 |
| Del Giglio, M | 1 |
| Schena, D | 1 |
| Girolomoni, G | 1 |
| Sangala, N | 1 |
| Lee, RW | 1 |
| Horsfield, C | 1 |
| Goldsmith, DJ | 1 |
| Marzano, AV | 1 |
| Vezzoli, P | 1 |
| Crosti, C | 1 |
| Katz, U | 1 |
| Zandman-Goddard, G | 1 |
| Akahoshi, T | 1 |
| Wada, T | 1 |
| Takemoto, T | 1 |
| Handler, J | 1 |
| Cartee, TV | 1 |
| Chen, SC | 1 |
| Oh, JY | 1 |
| Park, SJ | 1 |
| Shin, JI | 1 |
| Deng, C | 1 |
| Lu, Q | 3 |
| Zhang, Z | 1 |
| Rao, T | 1 |
| Attwood, J | 1 |
| Yung, R | 1 |
| Richardson, B | 3 |
| REINHARDT, DJ | 1 |
| WALDRON, JM | 1 |
| SHACKMAN, NH | 1 |
| SWILLER, AI | 1 |
| MORRISON, M | 1 |
| COMENS, P | 2 |
| SCHROEDER, HA | 1 |
| DUBOIS, EL | 1 |
| KATZ, YJ | 1 |
| FREEMAN, V | 1 |
| GARBAK, F | 1 |
| SIGUIER, F | 1 |
| BETOURNE, C | 1 |
| BONNET DE LA TOUR, J | 1 |
| Adhami, E | 1 |
| CIOBANU, V | 1 |
| VELICAN, D | 1 |
| HEINE, WI | 3 |
| FRIEDMAN, H | 3 |
| BRAVERMAN, IM | 1 |
| LERNER, AB | 1 |
| SHULMAN, LE | 1 |
| LEOPOLD, HC | 1 |
| GODWIN, B | 1 |
| STERNBERG, TH | 1 |
| BIERMAN, SM | 1 |
| VACHTENHEIM, J | 1 |
| HOLLEY, HL | 1 |
| OSHIMA, Y | 1 |
| HAZAMA, T | 1 |
| DEMARCO, P | 1 |
| SHOHOV, P | 1 |
| KRESKY, B | 1 |
| ZAINO, EC | 1 |
| GOLDBERG, LC | 1 |
| YAMAGUCHI, S | 1 |
| KOMIYA, M | 1 |
| ALARCON SEGOVIA, D | 1 |
| WORTHINGTON, JW | 2 |
| WARD, LE | 2 |
| WAKIM, KG | 2 |
| BONDARENKO, BB | 1 |
| ALARCON-SEGOVIA, D | 6 |
| SMITH, FG | 1 |
| LITMAN, N | 1 |
| LATTA, H | 1 |
| LANSBURY, J | 1 |
| ROGERS, FB | 1 |
| HENN, MJ | 1 |
| PARKIN, TW | 1 |
| HARGRAVES, MM | 1 |
| ODEL, HM | 1 |
| LELIS, II | 1 |
| Eisenberger, AB | 1 |
| Wu, A | 2 |
| Richardson, BC | 1 |
| Suwa, A | 1 |
| Singh, S | 1 |
| Finks, SW | 1 |
| Finks, AL | 1 |
| Self, TH | 1 |
| Birnbaum, B | 1 |
| Sidhu, GS | 1 |
| Smith, RL | 1 |
| Pillinger, MH | 1 |
| Tagoe, CE | 1 |
| Mazari, L | 1 |
| Ouarzane, M | 1 |
| Zouali, M | 1 |
| Gorelik, G | 1 |
| Fang, JY | 1 |
| Nonaka, Y | 1 |
| Takei, S | 1 |
| Zhou, Y | 1 |
| Siegel, M | 1 |
| Lee, SL | 2 |
| Peress, NS | 1 |
| Batchelor, JR | 5 |
| Welsh, KI | 1 |
| Tinoco, RM | 1 |
| Dollery, CT | 3 |
| Hughes, GR | 6 |
| Bernstein, R | 2 |
| Ryan, P | 2 |
| Naish, PF | 1 |
| Aber, GM | 1 |
| Bing, RF | 3 |
| Russell, GI | 3 |
| Brand, C | 1 |
| Davidson, A | 1 |
| Littlejohn, G | 1 |
| DeSwarte, RD | 1 |
| Sim, E | 8 |
| Gill, EW | 1 |
| Sim, RB | 2 |
| Christophidis, N | 1 |
| Reidenberg, MM | 2 |
| Shapiro, KS | 1 |
| Pinn, VW | 1 |
| Harrington, JT | 1 |
| Levey, AS | 1 |
| Peterson, LL | 1 |
| Ihle, BU | 1 |
| Whitworth, JA | 1 |
| Dowling, JP | 1 |
| Kincaid-Smith, P | 2 |
| Jacobs, RP | 1 |
| Blackshear, PJ | 1 |
| Rotner, HE | 1 |
| Kriauciunas, KA | 1 |
| Kahn, CR | 1 |
| Shoenfeld, Y | 1 |
| Isenberg, D | 1 |
| Cameron, HA | 2 |
| Ramsay, LE | 4 |
| Petty, R | 1 |
| Medley, DR | 1 |
| Merk, H | 1 |
| Weiser, GA | 1 |
| Forouhar, FA | 1 |
| White, WB | 1 |
| French, WJ | 1 |
| Conoley, S | 1 |
| Holt, RJ | 1 |
| Gaskins, JD | 1 |
| Wollina, U | 1 |
| Naparstek, Y | 1 |
| Kopolovic, J | 1 |
| Tur-Kaspa, R | 1 |
| Rubinger, D | 1 |
| Mansilla-Tinoco, R | 1 |
| Harland, SJ | 2 |
| Ryan, PJ | 1 |
| Bernstein, RM | 4 |
| Bulpitt, CJ | 1 |
| Morgan, A | 1 |
| Jones, JM | 1 |
| Silas, J | 1 |
| Freestone, S | 2 |
| Harmon, CE | 1 |
| Portanova, JP | 3 |
| Walport, MJ | 1 |
| Black, CM | 1 |
| Macleod, WN | 1 |
| Aylward, PE | 1 |
| Tonkin, AM | 1 |
| Bune, A | 1 |
| Carpenter, JR | 1 |
| McDuffie, FC | 1 |
| Sheps, SG | 1 |
| Spiekerman, RE | 1 |
| Brumfield, H | 1 |
| King, R | 1 |
| Thurston, H | 2 |
| Swales, JD | 2 |
| Litwin, A | 3 |
| Adams, LE | 2 |
| Zimmer, H | 3 |
| Foad, B | 1 |
| Loggie, JH | 1 |
| Hess, EV | 5 |
| Balazs, T | 1 |
| Robinson, CJ | 1 |
| Balter, N | 1 |
| Holborow, EJ | 1 |
| Rynes, RI | 1 |
| Gharavi, A | 1 |
| Ryan, PF | 2 |
| Sewell, J | 1 |
| Mansilla, R | 2 |
| Dubroff, LM | 2 |
| Reid, R | 1 |
| Papalian, M | 1 |
| Weinstein, A | 1 |
| Schoen, RT | 1 |
| Trentham, DE | 1 |
| Tan, EM | 4 |
| Ohe, A | 1 |
| Koda, S | 1 |
| Negoro, N | 1 |
| Okamura, M | 1 |
| Amatsu, K | 1 |
| Kohno, M | 1 |
| Kanayama, Y | 1 |
| Inoue, T | 1 |
| Takeda, T | 1 |
| Chisholm, JC | 1 |
| Perry, HM | 5 |
| Parker, CW | 1 |
| Neville, E | 1 |
| Graham, PY | 1 |
| Brewis, RA | 1 |
| Bass, BH | 1 |
| Reid, RJ | 1 |
| Drozdz, M | 4 |
| Facchini, V | 1 |
| Timbrell, JA | 1 |
| Santini, D | 1 |
| Fox, D | 1 |
| Kloner, RA | 1 |
| Konstam, M | 1 |
| Rude, RE | 1 |
| Lorell, BH | 1 |
| Alloway, JA | 1 |
| Salata, MP | 1 |
| Pauls, JD | 2 |
| Edworthy, SM | 1 |
| Fritzler, MJ | 2 |
| Schattner, A | 1 |
| Sthoeger, Z | 1 |
| Geltner, D | 1 |
| Jiang, X | 1 |
| Khursigara, G | 1 |
| Cohen, MG | 1 |
| Nässberger, L | 3 |
| Hultquist, R | 1 |
| Sturfelt, G | 2 |
| Cambridge, G | 1 |
| Wallace, H | 1 |
| Leaker, B | 1 |
| Miyasaka, N | 1 |
| Pirmohamed, M | 1 |
| Hari, CK | 1 |
| Raza, SA | 1 |
| Clayton, MI | 1 |
| Amano, K | 1 |
| Takeuchi, T | 1 |
| Drayer, DE | 1 |
| Jones, WN | 1 |
| Trinca, CE | 1 |
| Walson, PD | 1 |
| Irias, JJ | 1 |
| CHase, PH | 1 |
| Kucharz, E | 1 |
| Carel, RS | 1 |
| Shapiro, MS | 1 |
| Cordoba, O | 1 |
| Taragan, R | 1 |
| Gutman, A | 1 |
| Chatterjee, K | 1 |
| Massie, B | 1 |
| Rubin, S | 1 |
| Gelberg, H | 1 |
| Brundage, BH | 1 |
| Ports, TA | 1 |
| Holm, G | 1 |
| Pinnas, JL | 1 |
| Fenster, PE | 1 |
| Dandavino, R | 1 |
| Bach, JF | 1 |
| Yamauchi, Y | 2 |
| Anderson, B | 1 |
| Stillman, MT | 1 |
| Kissin, MW | 1 |
| Williamson, RC | 1 |
| Fakri, E | 1 |
| François, B | 1 |
| Wechsler, B | 1 |
| Brion, NO | 1 |
| Colau, C | 1 |
| Ximenes, H | 1 |
| Godeau, P | 1 |
| Schwarz, JA | 1 |
| Weinstein, J | 1 |
| Jensen, HE | 1 |
| Rasmussen, K | 2 |
| Koch-Weser, J | 2 |
| Adams, L | 1 |
| Schubothe, H | 1 |
| Maas, D | 2 |
| Berkowitz, HS | 1 |
| Strandberg, I | 1 |
| Boman, G | 1 |
| Hassler, L | 2 |
| Sjöqvist, F | 1 |
| Fishbein, E | 2 |
| Cohmen, G | 1 |
| Johansson, M | 1 |
| Manhem, P | 1 |
| Yonga, GO | 1 |
| Kraus, A | 1 |
| Zacharias, W | 1 |
| Koopman, WJ | 1 |
| Gohill, J | 1 |
| Gatenby, PA | 1 |
| Juanola, X | 1 |
| Nolla, JM | 1 |
| Servitje, O | 1 |
| Valverde, J | 1 |
| Sjöholm, AG | 1 |
| Jonsson, H | 1 |
| Akesson, A | 1 |
| Ramsey-Goldman, R | 1 |
| Franz, T | 1 |
| Solano, FX | 1 |
| Medsger, TA | 1 |
| Mulder, H | 1 |
| Richards, FM | 1 |
| Fulkerson, WJ | 1 |
| Jendryczko, A | 1 |
| Magner, K | 1 |
| Arndt, RE | 1 |
| Kotzin, BL | 1 |
| Craft, JE | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Monitoring the IMmUological TOXicity of Drugs[NCT03480529] | 662 participants (Actual) | Observational [Patient Registry] | 2018-03-01 | Completed | |||
| Fasting Hypoglycemia: Diagnosis and Treatment[NCT00001276] | 1,500 participants (Anticipated) | Observational | 1991-05-21 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
44 reviews available for hydralazine and Libman-Sacks Disease
| Article | Year |
|---|---|
Drug-induced lupus erythematosus: an update on drugs and mechanisms.
Topics: Autoimmunity; Genetic Predisposition to Disease; Humans; Hydralazine; Immunologic Factors; Lupus Ery | 2018 |
Mechanistic Insights of Chemicals and Drugs as Risk Factors for Systemic Lupus Erythematosus.
Topics: Autoimmune Diseases; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Risk | 2020 |
Drug-induced lupus erythematosus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Antibodies; Antifungal Ag | 2009 |
Drug-induced lupus: an update on its dermatologic aspects.
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Antitubercular Agents; Autoa | 2009 |
Drug-induced lupus: an update.
Topics: Anti-Arrhythmia Agents; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Tumor Necr | 2010 |
[Fever induced by various drugs].
Topics: Amphetamine; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Body Temperature Regulation; | 2009 |
DNA methylation and autoimmune disease.
Topics: Animals; Autoimmune Diseases; Autoimmunity; Azacitidine; Cell Communication; DNA Methylation; Humans | 2003 |
[Immunologic tests: Anti-histone antibodies].
Topics: Antibodies, Antinuclear; Biomarkers; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Techniq | 2005 |
Hydralazine-induced lupus: maintaining vigilance with increased use in patients with heart failure.
Topics: Heart Failure; Humans; Hydralazine; Lupus Erythematosus, Systemic; Risk Factors; Sex Factors; Vasodi | 2006 |
[Drug-induced lupus erythematosus].
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; Hu | 2007 |
DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients.
Topics: Autoantibodies; B-Lymphocytes; CD4-Positive T-Lymphocytes; Cytokines; Cytotoxicity, Immunologic; DNA | 2008 |
Drug-induced lupus: clinical and serological studies.
Topics: Acetyltransferases; Adult; Antibodies, Antinuclear; Anticonvulsants; Arthritis; Chlorpromazine; Cros | 1982 |
The immunogenetics of SLE.
Topics: Animals; Antibodies, Antinuclear; Autoantibodies; Female; Gene Frequency; Genes, MHC Class II; Histo | 1982 |
Drug-induced systemic lupus erythematosus.
Topics: Antibodies, Antinuclear; Anticonvulsants; Chlorpromazine; Humans; Hydralazine; Isoniazid; Lupus Eryt | 1980 |
Drug-induced lupus: an adjuvant disease?
Topics: Adjuvants, Immunologic; Animals; Autoimmune Diseases; Humans; Hydralazine; Lupus Erythematosus, Syst | 1981 |
Quinidine-induced rheumatic syndromes.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Atrial Fibrillation; Child; Diagnosis, Diff | 1995 |
Drug-induced lupus.
Topics: Antibodies, Antinuclear; Anticonvulsants; Ethosuximide; Female; Humans; Hydralazine; Lupus Erythemat | 1996 |
Hydralazine-induced lupus and vocal fold paralysis.
Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Middle Aged; Vo | 1998 |
[Drug-induced lupus erythematosus].
Topics: Autoimmunity; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydr | 2000 |
Drug-induced systemic lupus erythematosus: a critical review.
Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agen | 1975 |
Drug therapy. Hydralazine.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Blood Pressure; Cardiac Output; Chronic Disease; Dru | 1976 |
Drug-related lupus syndromes and their relationship to spontaneously occurring systemic lupus erythematosus.
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus Erythematosus, Systemic; | 1991 |
Drug-induced immune complex disease.
Topics: Amino Acid Sequence; Antigen-Antibody Complex; Complement Activation; Complement C4; Humans; Hydrala | 1991 |
The role of complement in the aetiopathogenesis of systemic lupus erythematosus.
Topics: Antigen-Antibody Complex; Complement Pathway, Classical; Complement System Proteins; HLA Antigens; H | 1991 |
Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature.
Topics: Acute Disease; Adult; Fever; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Neutrophils; | 1990 |
Drug-induced immune-complex disease.
Topics: Humans; Hydralazine; Immune Complex Diseases; Isoniazid; Lupus Erythematosus, Systemic; Penicillamin | 1989 |
Bullous systemic lupus erythematosus.
Topics: Adult; Aged; Dapsone; Female; Fluorescent Antibody Technique; Humans; Hydralazine; Lupus Erythematos | 1989 |
[Drug-induced lupus].
Topics: Acetylation; Adrenergic beta-Antagonists; Antibodies, Antinuclear; Anticonvulsants; B-Lymphocytes; D | 1985 |
The evolution of antihypertensive therapy.
Topics: Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood Pressure; Calcium Channel Blockers; | 1985 |
Drug-induced autoimmune disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Gold; HLA Antigens; Humans; Hydralazine; Lupus Erythemat | 1987 |
[Pathogenesis of drug-induced collagenosis-like syndrome].
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide | 1987 |
Connective tissue disease in the elderly.
Topics: Aged; Connective Tissue Diseases; Dermatomyositis; Female; Giant Cell Arteritis; Humans; Hydralazine | 1986 |
Drug-induced systemic lupus erythematosus. Differentiating it from the real thing.
Topics: Diagnosis, Differential; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male | 1985 |
Drug-induced lupus: clinical spectrum and pathogenesis.
Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Black | 1985 |
Systemic lupus erythematosus.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Hepatitis; Humans; Hydralazine; Immunoglobul | 1973 |
[Iatrogenic lupus: present status of the problem. II. Physiopathology of induced lupus].
Topics: Animals; Antibodies, Antinuclear; Disease Models, Animal; DNA, Viral; Drug-Related Side Effects and | 1972 |
Antinuclear antibodies.
Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Autoantigens; Cytotoxic | 1972 |
Lupus-like syndromes induced by drugs.
Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stra | 1974 |
[Generalized lupus erythematosus caused by methyl-phenyl-ethyl-hydantoin].
Topics: Adult; Autoimmune Diseases; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; M | 1967 |
[Antinuclear factors. Demonstration and clinico-diagnostic significance].
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Chronic Disease | 1969 |
Late toxicity to hydralazine resembling systemic lupus erythematosus or rheumatoid arthritis.
Topics: Acetylation; Adult; Antibodies, Antinuclear; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Bloo | 1973 |
Vasodilator drugs in the treatment of hypertension.
Topics: Administration, Oral; Cardiac Output; Diazoxide; Diuretics; Dose-Response Relationship, Drug; Drug S | 1974 |
Drug-induced lupus syndromes.
Topics: Antibodies, Antinuclear; Anticonvulsants; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Syste | 1969 |
[Lupus erythematosus and the hydralazine syndrome].
Topics: Animals; Dogs; Guinea Pigs; Humans; Hydralazine; Lupus Erythematosus, Systemic | 1966 |
1 trial available for hydralazine and Libman-Sacks Disease
| Article | Year |
|---|---|
[Experience with the combination of beta receptor blockader and hydralazine in the treatment of hypertension].
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Headache; Human | 1976 |
216 other studies available for hydralazine and Libman-Sacks Disease
| Article | Year |
|---|---|
Overlapping drug-induced vasculitis, ANCA-associated vasculitis, and lupus nephritis caused by low-dose hydralazine.
Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; | 2023 |
In vivo ameliorative effects of vitamin E against hydralazine-induced lupus.
Topics: Animals; Humans; Hydralazine; Lupus Erythematosus, Systemic; Mice; Vitamin E | 2023 |
Severe hydralazine-induced lupus presenting as systemic lupus erythematosus.
Topics: Adult; Antibodies, Antinuclear; Autoantibodies; Drug Eruptions; Female; Humans; Hydralazine; Lupus E | 2020 |
Hydralazine-associated vasculitis: Overlapping features of drug-induced lupus and vasculitis.
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Female; Humans; Hydralazine; | 2018 |
Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database.
Topics: Adalimumab; Adult; Antirheumatic Agents; Databases, Factual; Etanercept; Female; Humans; Hydralazine | 2019 |
Hydralazine-induced lupus syndrome presenting with large pericardial effusion.
Topics: Aged; Antihypertensive Agents; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Pericardi | 2014 |
Combined ANCA-associated vasculitis and lupus syndrome following prolonged use of hydralazine: a timely reminder of an old foe.
Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antihypertensive Agents; Female; Humans; | 2010 |
Hydralazine-induced lupus erythematosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Drug Therapy, Combination; F | 2012 |
Sweet syndrome associated with hydralazine-induced lupus erythematosus.
Topics: Antibodies, Antinuclear; Antihypertensive Agents; Diagnosis, Differential; Humans; Hydralazine; Hype | 2012 |
Hydralazine-induced lupus erythematosus: what is the mechanism?
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Humans; Hydralazine; Hypertension; Interl | 2012 |
Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling.
Topics: Animals; Autoimmunity; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine- | 2003 |
Lupus erythematosus-like syndrome complicating hydralazine (apresoline) therapy.
Topics: Arthritis; Arthritis, Rheumatoid; Diagnosis, Differential; Humans; Hydralazine; Lupus Erythematosus, | 1954 |
Syndrome simulating acute disseminated lupus erythematosus: appearance after hydralazine (apresoline) therapy.
Topics: Diagnosis, Differential; Humans; Hydralazine; Lupus Erythematosus, Systemic; Sympatholytics; Syndrom | 1954 |
The L. E. cell as a manifestation of delayed hydralazine intoxication.
Topics: Child; Death; Death, Sudden; Humans; Hydralazine; Infant; Lupus Erythematosus, Systemic; Poisoning; | 1956 |
Experimental hydralazine disease and its similarity to disseminated lupus erythematosus.
Topics: Diagnosis, Differential; Humans; Hydralazine; Lupus Erythematosus, Systemic; Sympatholytics | 1956 |
Chronic toxicity studies of hydralazine (apresoline) in dogs with particular reference to the production of the hydralazine syndrome.
Topics: Animals; Dogs; Hydralazine; Lupus Erythematosus, Systemic | 1957 |
[Hydralazine-induced lupus erythematosus].
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic | 1958 |
A predictive equation for drug-induced lupus.
Topics: Autoantibodies; Humans; Hydralazine; Lupus Erythematosus, Systemic; Models, Theoretical; Vasodilator | 2003 |
[Hydralazine syndrome after prolonged treatment with adelphan].
Topics: Hydralazine; Hydrazines; Hypertension; Lupus Erythematosus, Systemic; Reserpine | 1961 |
Hydralazine lupus syndrome associated with a possible antihydralazine antibody.
Topics: Angina Pectoris; Antibodies; Humans; Hydralazine; Hypertension; Immunoglobulins; Lupus Erythematosus | 1962 |
Hydralazine-induced lupus erythematosus associated with a possible anti-hydralazine antibody.
Topics: Antigen-Antibody Reactions; Hemagglutination; Hemagglutination Tests; Humans; Hydralazine; Lupus Ery | 1962 |
Demonstration of anti-hydralazine antibody in hydralazine induced lupus erythematosus.
Topics: Antibodies; Humans; Hydralazine; Lupus Erythematosus, Systemic | 1963 |
Hydralazine disease in the guinea-pig as an experimental model for lupus erythematosus.
Topics: Guinea Pigs; Humans; Hydralazine; Lupus Erythematosus, Systemic; Models, Theoretical | 1962 |
INDUCING AGENTS AND RELATIONSHIP TO OTHER DISEASES.
Topics: Anticonvulsants; Drug Hypersensitivity; Humans; Hydralazine; Lupus Erythematosus, Discoid; Lupus Ery | 1963 |
LE CELLS IN CHRONIC BRONCHIAL ASTHMA.
Topics: Antigen-Antibody Reactions; Asthma; DNA; Hydralazine; Lupus Erythematosus, Systemic; Neutrophils; To | 1963 |
UNIQUE SYNDROMES INVOLVING THE SKIN INDUCED BY DRUGS, FOOD ADDITIVES, AND ENVIRONMENTAL CONTAMINANTS.
Topics: Aniline Compounds; Anti-Bacterial Agents; Dermatitis, Contact; Diagnosis, Differential; Drug Eruptio | 1963 |
[PROVOCATING FACTORS IN SYSTEMIC LUPUS ERYTHEMATOSUS (WITH REFERENCE TO THERAPEUTIC AGENTS)].
Topics: Anticonvulsants; Antitubercular Agents; Autoimmune Diseases; Drug Hypersensitivity; Drug Therapy; Go | 1963 |
[IMMUNOLOGICAL ASPECTS OF COLLAGEN DISEASES].
Topics: Agammaglobulinemia; Allergy and Immunology; Anticonvulsants; Antigens; Autoantibodies; Collagen Dise | 1964 |
DRUGS AND THE 'LUPUS DIATHESIS'.
Topics: Anticonvulsants; Autoantibodies; Disease Susceptibility; Drug Hypersensitivity; gamma-Globulins; Hyd | 1964 |
[COLLAGEN DISEASES].
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Rheumatoid; Behcet Syndrome; Child; Collagen Disease | 1964 |
DISSEMINATED LUPUS ERYTHEMATOSUS IN A 28-MONTH-OLD INFANT WITH ONSET DURING HYDRALAZINE THERAPY.
Topics: Blood Transfusion; Cerebral Palsy; Child; Diseases in Twins; Erythroblastosis, Fetal; Fetus; Hydrala | 1964 |
A THIRTY YEAR EVALUATION OF LUPUS ERYTHEMATOSUS.
Topics: Adrenal Cortex Hormones; Anticonvulsants; Antitubercular Agents; Appetite Depressants; Chloroquine; | 1964 |
[ERYTHEMATOSUS AND AUTOIMMUNITY].
Topics: Animals; Autoantibodies; Autoimmune Diseases; Autoimmunity; DNA; Hydralazine; Lupus Erythematosus, S | 1964 |
LUPUS DIATHESIS AND THE HYDRALAZINE SYNDROME.
Topics: Disease Susceptibility; Drug Therapy; Genetics, Medical; Hydralazine; Hypertension; Lupus Erythemato | 1965 |
[UNUSUAL COURSE OF THE HYDRALAZINE SYNDROME].
Topics: Drug Therapy; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Toxicology | 1965 |
LUPUS DIATHESIS.
Topics: Allergy and Immunology; Disease Susceptibility; Drug Hypersensitivity; Humans; Hydralazine; Hyperten | 1965 |
LUPUS GLOMERULONEPHRITIS. THE EFFECT OF LARGE DOSES OF CORTICOSTEROIDS ON RENAL FUNCTION AND RENAL LESIONS IN TWO CHILDREN.
Topics: Adolescent; Adrenal Cortex Hormones; Cortisone; Drug Therapy; Glomerulonephritis; Guanethidine; Hydr | 1965 |
The hydralazine syndrome.
Topics: Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Rheumatic Diseases; Sympatholytics | 1955 |
Acute systemic lupus erythematosus syndrome from hydralazine hydrochloride.
Topics: Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Sympatholytics; Syndrome | 1955 |
[Hydralazine syndrome and experimental lupus erythematosus].
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic | 1962 |
Isosorbide dinitrate and hydralazine in blacks with heart failure.
Topics: Black People; Drug Therapy, Combination; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; L | 2005 |
Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs.
Topics: 5' Flanking Region; Adult; Antigens, CD; Base Sequence; CD27 Ligand; Cells, Cultured; DNA Methylatio | 2005 |
Hydralazine-induced lupus.
Topics: Female; Heart Failure; Humans; Hydralazine; Lupus Erythematosus, Systemic; Risk Factors; Vasodilator | 2006 |
Fulminating hydralazine-induced lupus pneumonitis.
Topics: Adult; Antihypertensive Agents; Fatal Outcome; Female; Humans; Hydralazine; Lung; Lung Diseases, Int | 2006 |
Subversion of B lymphocyte tolerance by hydralazine, a potential mechanism for drug-induced lupus.
Topics: Animals; Autoantibodies; B-Lymphocytes; DNA-Binding Proteins; Flavonoids; Gene Expression Regulation | 2007 |
Impaired T cell protein kinase C delta activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus.
Topics: Adult; Aged; CD27 Ligand; Cells, Cultured; DNA Methylation; Down-Regulation; Extracellular Signal-Re | 2007 |
Clinical and experimental studies on the hydralazine syndrome and its relationship to systemic lupus erythematosus.
Topics: Adult; Aged; Animals; Collagen Diseases; Dogs; Female; Humans; Hydralazine; Lupus Erythematosus, Sys | 1967 |
The epidemiology of drug-induced systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension; | 1967 |
Hydralazine-induced systemic lupus erythematosus: influence of HLA-DR and sex on susceptibility.
Topics: Acetylation; Female; Genes, MHC Class II; HLA Antigens; Humans; Hydralazine; Lupus Erythematosus, Sy | 1980 |
Hypotensive agents, beta-blockers, and drug-induced lupus.
Topics: Adrenergic beta-Antagonists; Antibodies, Antinuclear; Humans; Hydralazine; Lupus Erythematosus, Syst | 1982 |
Hydralazine-induced lupus: no association with HLA-DR4.
Topics: Disease Susceptibility; Female; Histocompatibility Antigens Class II; HLA-DR4 Antigen; Humans; Hydra | 1984 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons | 1984 |
Drugs that induce systemic lupus erythematosus inhibit complement component C4.
Topics: Acetylation; Complement C4; Complement Pathway, Classical; Humans; Hydralazine; Iproniazid; Isoniazi | 1984 |
Complement C4 and drug-induced SLE.
Topics: Complement C4; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic | 1984 |
Drug-induced lupus.
Topics: Histocompatibility Antigens Class II; HLA-DR3 Antigen; Humans; Hydralazine; Lupus Erythematosus, Sys | 1984 |
The chemical induction of systemic lupus erythematosus and lupus-like illnesses.
Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythemato | 1981 |
Immune complex glomerulonephritis in hydralazine-induced SLE.
Topics: Aged; Arteritis; Female; Glomerulonephritis; Humans; Hydralazine; Immune Complex Diseases; Kidney Di | 1984 |
Hydralazine-induced systemic lupus erythematosus presenting as pyoderma gangrenosum-like ulcers.
Topics: Antibodies, Antinuclear; Autoantibodies; Drug Eruptions; Female; Humans; Hydralazine; Lupus Erythema | 1984 |
Hydralazine and lupus nephritis.
Topics: Adult; Aged; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Immune Complex Diseases; | 1984 |
Drug-induced rheumatic diseases.
Topics: Adrenal Cortex Hormones; Anticonvulsants; Antineoplastic Agents; Diuretics; Gout; Heparin; Humans; H | 1984 |
Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosus.
Topics: Aged; Autoantibodies; Autoimmune Diseases; Female; Glucose Tolerance Test; Humans; Hydralazine; Hypo | 1983 |
Transient monoclonal gammopathy in hydralazine induced lupus erythematosus.
Topics: Antibodies, Monoclonal; Humans; Hydralazine; Hypergammaglobulinemia; Lupus Erythematosus, Systemic | 1983 |
The lupus syndrome induced by hydralazine: a common complication with low dose treatment.
Topics: Adult; Aged; Drug Administration Schedule; England; Female; Humans; Hydralazine; Longitudinal Studie | 1984 |
The lupus syndrome induced by hydralazine.
Topics: Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Statistics as Topic | 1984 |
Cutaneous manifestations of hydrallazine toxicity.
Topics: Adult; Drug Eruptions; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Pregnancy; Pregna | 1980 |
Renal failure, dyspnea and anemia in a 57 year old woman. Clinicopathologic conference.
Topics: Anemia; Diagnosis, Differential; Dyspnea; Female; Glomerulonephritis; Humans; Hydralazine; Hypertens | 1981 |
[Pathogenesis of systemic lupus erythematosus: effect of aromatic amines].
Topics: Acetylation; Acyltransferases; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Phenotype | 1984 |
Hydralazine hoarseness. A new appearance of drug-induced systemic lupus erythematosus.
Topics: Epiglottis; Hoarseness; Humans; Hydralazine; Laryngeal Diseases; Lupus Erythematosus, Systemic; Male | 1984 |
Hydralazine-induced lupus syndrome.
Topics: Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged; Prednisone | 1984 |
Arthritis as an iatrogenic disease.
Topics: Arthritis; Humans; Hydralazine; Iatrogenic Disease; Lupus Erythematosus, Systemic; Sulfadiazine | 1984 |
Pharmacokinetics of hydralazine and the first pass effect.
Topics: Humans; Hydralazine; Intestinal Absorption; Intestinal Mucosa; Kidney; Kidney Failure, Chronic; Kine | 1983 |
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus | 1984 |
Focal glomerulonephritis in the course of hydralazine-induced lupus syndrome.
Topics: Biopsy; Glomerulonephritis; Humans; Hydralazine; Hypertension; Kidney; Lupus Erythematosus, Systemic | 1984 |
Hydralazine, antinuclear antibodies, and the lupus syndrome.
Topics: Acetylation; Antibodies, Antinuclear; Dose-Response Relationship, Drug; Female; Humans; Hydralazine; | 1982 |
Hydralazine antinuclear antibodies and the lupus syndrome.
Topics: Antibodies, Antinuclear; Humans; Hydralazine; Lupus Erythematosus, Systemic | 1982 |
Transient monoclonal gammopathy in hydralazine-induced lupus erythematosus.
Topics: Female; Humans; Hydralazine; Hypergammaglobulinemia; Immunoglobulin M; Lupus Erythematosus, Systemic | 1982 |
Anaemia in the hydrallazine-induced Lupus syndrome.
Topics: Aged; Anemia; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Syndrome; Vasculitis | 1983 |
Cardiac tamponade in hydrallazine-induced systemic lupus erythematosus.
Topics: Cardiac Tamponade; DNA; Echocardiography; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; | 1982 |
Prospective study of immune response to hydralazine and development of antideoxyribonucleoprotein in patients receiving hydralazine.
Topics: Antibodies; Antibodies, Antinuclear; Antibody Formation; Deoxyribonucleoproteins; DNA; Humans; Hydra | 1980 |
Hydrallazine in hypertension: is there a safe dose?
Topics: Adult; Antibodies; Antibodies, Antinuclear; DNA; Female; Humans; Hydralazine; Hypertension; Lupus Er | 1980 |
Prospective study of immunologic effects of hydralazine in hypertensive patients.
Topics: Acetylation; Adolescent; Adult; Antibodies, Antinuclear; Autoimmune Diseases; Female; Humans; Hydral | 1981 |
Hydralazine-induced antinuclear antibodies in beagle dogs.
Topics: Animals; Antibodies, Antinuclear; Antibody Specificity; Disease Models, Animal; Dogs; Female; Heart | 1981 |
Drug effects on autoantibodies and immune complexes.
Topics: Acetylation; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodie | 1980 |
The heterogeneity of serologic findings and predisposing host factors in drug-induced lupus erythematosus.
Topics: Acetylation; Antibodies, Antinuclear; Antilymphocyte Serum; Arthritis, Rheumatoid; Complement Fixati | 1981 |
Immunologic effects of hydralazine in hypertensive patients.
Topics: Acetylation; Adult; Antibodies, Antinuclear; Autoimmune Diseases; Binding Sites, Antibody; Coombs Te | 1981 |
Molecular models for hydralazine-related systemic lupus erythematosus.
Topics: Antibodies, Antinuclear; Chromatin; DNA; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemi | 1981 |
The role of histones as nuclear autoantigens in drug-related lupus erythematosus.
Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Antibody Specificity; Antigens; Autoantigens; | 1981 |
Drug-related lupus.
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide | 1982 |
A case of hydralazine-induced lupus erythematosus with circulating antibodies to native DNA.
Topics: Antibodies; DNA; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Middle Aged | 1982 |
Acute low-dose hydralazine induced lupus syndrome (HILS).
Topics: Adult; Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic | 1981 |
Introduction to drug-related lupus.
Topics: Acetylation; Acetyltransferases; Animals; Anticonvulsants; Autoimmune Diseases; Child; Chlorpromazin | 1981 |
Possible mechanisms of the hydralazine-related lupus-like syndrome.
Topics: Anemia, Hypochromic; Anticholesteremic Agents; Blood Pressure; Diastole; Dose-Response Relationship, | 1981 |
Hapten immunology and allergic reactions in humans.
Topics: Animals; Autoimmune Diseases; Carrier Proteins; Drug Hypersensitivity; Environmental Health; Haptens | 1981 |
Orogenital ulcers, SLE and hydralazine.
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Middle Aged; Mouth Diseases; Penile Diseas | 1981 |
Hydralazine lung.
Topics: Female; Humans; Hydralazine; Lung Diseases; Lupus Erythematosus, Systemic; Middle Aged | 1981 |
Hydralazine-pyrimidine interactions may explain hydralazine-induced lupus erythematosus.
Topics: DNA; Hydralazine; Lupus Erythematosus, Systemic; Photochemistry; Pyrimidines | 1980 |
[Studies on metabolism of collagen in rats with experimentally induced collagen-like syndrome (author's transl)].
Topics: Animals; Collagen; Hydralazine; Lupus Erythematosus, Systemic; Rats; Todralazine | 1980 |
Hydrallazine-induced lupus erythematosus-like syndrome in a patient of the rapid acetylator phenotype.
Topics: Acetylation; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Middle Aged; Phenotype; Sul | 1980 |
Pulmonary hypertension in systemic lupus erythematosus: hemodynamics and effects of vasodilator therapy.
Topics: Adult; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Lupus Erythematosus, Syst | 1980 |
Epitope mapping of histone 5 (H5) with systemic lupus erythematosus, procainamide-induced lupus and hydralazine-induced lupus sera.
Topics: Amino Acid Sequence; Antibody Specificity; Autoantibodies; Blotting, Western; Epitopes; Histones; Hu | 1993 |
Effect of acute cytomegalovirus infection on drug-induced SLE.
Topics: Acute Disease; Autoimmune Diseases; Cytomegalovirus Infections; Disease Susceptibility; Female; Huma | 1994 |
Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils.
Topics: Animals; Biological Assay; Biotransformation; Cell Death; Chlorpromazine; Humans; Hydralazine; Hydro | 1994 |
Antibodies to dsDNA in drug induced lupus erythematosus.
Topics: Antibodies, Antinuclear; Artifacts; DNA; Humans; Hydralazine; Lupus Erythematosus, Systemic; Nucleic | 1994 |
Occurrence of anti-lactoferrin antibodies in patients with systemic lupus erythematosus, hydralazine-induced lupus, and rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Female; Humans; H | 1994 |
Autoantibodies to myeloperoxidase in idiopathic and drug-induced systemic lupus erythematosus and vasculitis.
Topics: Adolescent; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic; Antibody Specificity; Autoantibodie | 1994 |
Hydralazine-induced lupus: yet another autoantibody!
Topics: Antibodies, Antinuclear; Antihypertensive Agents; DNA; Humans; Hydralazine; Lupus Erythematosus, Sys | 1996 |
Clinical consequences of polymorphic acetylation of basic drugs.
Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Hum | 1977 |
Drug-induced systemic lupus erythematosus.
Topics: Anticonvulsants; Antihypertensive Agents; Antipsychotic Agents; Antitubercular Agents; Female; Human | 1978 |
Hydralazine-induced lupus erythematosus-like syndrome.
Topics: Acetylation; Acetyltransferases; Antibodies, Antinuclear; Arthritis, Rheumatoid; Child; DNA; Drug Hy | 1975 |
Haematological changes in experimental hydralazine-induced collagen-like syndrome in guinea pigs.
Topics: Animals; Cell Count; Collagen Diseases; Erythrocytes; Guinea Pigs; Hematocrit; Hemoglobins; Hydralaz | 1978 |
LE cells in pleural fluid.
Topics: Aged; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Neutrophils; Pleural Effusion; Pro | 1979 |
Lymphocytotoxic antibodies in hydralazine-induced lupus erythematosus.
Topics: Antibodies, Antinuclear; Antibody-Dependent Cell Cytotoxicity; Humans; Hydralazine; Hypertension; Lu | 1979 |
Long-term outpatient vasodilator therapy of congestive heart failure. Consideration of agents at rest and during exercise.
Topics: Chronic Disease; Drug Therapy, Combination; Heart Failure; Heart Ventricles; Hemodynamics; Humans; H | 1978 |
Immunological side-effects of antihypertensive drugs.
Topics: Anemia, Hemolytic, Autoimmune; Antihypertensive Agents; Autoimmune Diseases; Female; Humans; Hydrala | 1979 |
ANA, DNA, and SLE.
Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; DNA; Humans; Hydralazine; Lupus Erythematosus | 1977 |
[Disseminated lupus erythematosus: etiopathogenic factors].
Topics: Animals; Antibodies; Autoantibodies; B-Lymphocytes; Female; Humans; Hydantoins; Hydralazine; Isoniaz | 1977 |
[Studies on the pathogenesis of hydralazine-induced lupus erythematosus-like syndrome (author's transl)].
Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Antigen-Antibody Reactions; DNA; Hydralazine; | 1979 |
False-positive FTA-ABS in hydralazine-induced lupus.
Topics: Aged; False Positive Reactions; Female; Fluorescent Antibody Technique; Humans; Hydralazine; Lupus E | 1978 |
Hydrallazine-induced SLE-like syndrome presenting as a leg ulcer.
Topics: Humans; Hydralazine; Hypertension, Malignant; Leg Ulcer; Lupus Erythematosus, Systemic; Male; Middle | 1979 |
[Can lupus be caused by dihydralazine?].
Topics: Adult; Aged; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic | 1979 |
[Lupus erythematosus induced by dihydralazine].
Topics: Dihydralazine; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Middle Aged | 1979 |
[Drug-induced disorders of lupus erythematosus type (author's transl)].
Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse | 1977 |
Hypocomplementemia in hydralazine-associated systemic lupus erythematosus.
Topics: Aged; Blood Coagulation Tests; Complement System Proteins; Humans; Hydralazine; Lupus Erythematosus, | 1978 |
Induction of antibodies to nuclear antigens in rabbits by immunization with hydralazine-human serum albumin conjugates.
Topics: Animals; Antibodies; Antibodies, Antinuclear; Antibody Formation; Antigens; Binding Sites, Antibody; | 1975 |
[Dihydralazine-induced hepatitis].
Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Hypertension; Lupus Eryt | 1977 |
[Drug-induced systemic lupus erythematosus (author's transl)].
Topics: Adolescent; Aged; Anti-Bacterial Agents; Antibody Formation; Autoantibodies; Child; Chlorpromazine; | 1977 |
Letter: Disseminated lupus erythematosus syndrome associated with hydrazaline.
Topics: Adult; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic | 1976 |
Acetylator phenotype in patients with hydralazine-induced lupoid syndrome.
Topics: Acetylation; Administration, Oral; Adult; Age Factors; Aged; Female; Half-Life; Humans; Hydralazine; | 1976 |
Patterns of antinuclear antibodies and lupus-activating drugs.
Topics: Antibodies, Antinuclear; Anticonvulsants; Antigens; Chlorpromazine; Female; Humans; Hydralazine; Iso | 1975 |
[Drug-induced lupus erythematosus-like syndromes].
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Anticonvulsants; Drug-Related Side Effects and Adv | 1976 |
[SLE-syndrome with exophthalmus after treatment with hydralazine].
Topics: Exophthalmos; Humans; Hydralazine; Hypertension, Renal; Lupus Erythematosus, Systemic; Male; Middle | 1975 |
Re: Low dose hydralazine induced lupus.
Topics: Adult; Female; Hospitals, Public; Humans; Hydralazine; Kenya; Lupus Erythematosus, Systemic; Middle | 1992 |
Autoantibody specificity in drug-induced lupus and neutrophil-mediated metabolism of lupus-inducing drugs.
Topics: Antibody Specificity; Autoantibodies; Chromatin; Histones; Humans; Hydralazine; Lupus Erythematosus, | 1992 |
Lupus-inducing drugs alter the structure of supercoiled circular DNA domains.
Topics: Acecainide; Animals; Antibodies; Canavanine; DNA, Superhelical; Electrophoresis, Agar Gel; Escherich | 1990 |
Antibodies from patients with systemic lupus erythematosus and drug-induced lupus bind determinants on histone 5 (H5).
Topics: Amino Acid Sequence; Animals; Autoantibodies; Chickens; Cross Reactions; Epitopes; Histones; Humans; | 1990 |
[Antibodies against lysosomal enzymes in neutrophil granulocytes are markers in systemic vasculites].
Topics: Autoantibodies; Biomarkers; Humans; Hydralazine; Lupus Erythematosus, Systemic; Lysosomes; Neutrophi | 1991 |
Hydralazine induced lupus and Sweet's syndrome.
Topics: Aged; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Skin Diseases; Syndrome | 1991 |
Autoantibodies against neutrophil cytoplasm components in systemic lupus erythematosus and in hydralazine-induced lupus.
Topics: Autoantibodies; Autoantigens; Cytoplasm; Female; Follow-Up Studies; Humans; Hydralazine; Lupus Eryth | 1990 |
Conversion of drug-induced SLE-syndrome by the vasodilating agent cadralazine.
Topics: Adult; Blood Pressure; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Pyrid | 1990 |
Constrictive pericarditis due to hydralazine-induced lupus erythematosus.
Topics: Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged; Pericarditis, C | 1990 |
Antilupus activity of copper (II).
Topics: Animals; Collagen Diseases; Copper; Free Radicals; Hydralazine; Lupus Erythematosus, Systemic; Male; | 1985 |
Anti-histone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Epitopes; Histones; Humans; H | 1987 |
Autoantigenic histone epitopes: a comparison between procainamide- and hydralazine-induced lupus.
Topics: Autoantigens; Epitopes; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide | 1987 |
Complement system protein C4 and susceptibility to hydralazine-induced systemic lupus erythematosus.
Topics: Alleles; Complement C3; Complement C3a; Complement C4; Complement C4a; Disease Susceptibility; Genet | 1989 |
CR1 polymorphism in hydralazine-induced systemic lupus erythematosus: DNA restriction fragment length polymorphism.
Topics: Alleles; Antigen-Antibody Complex; Erythrocytes; Hydralazine; Lupus Erythematosus, Systemic; Polymor | 1989 |
Size polymorphism of the erythrocyte complement receptor type 1 (CR1) in systemic lupus erythematosus induced by hydralazine.
Topics: Erythrocyte Membrane; Gene Frequency; Genes; Humans; Hydralazine; Lupus Erythematosus, Systemic; Phe | 1989 |
Cadralazine challenge in patients with previous hydralazine-induced lupus: a 6-month study.
Topics: Acetylation; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Lupu | 1989 |
Effects of hydrazyl group containing drugs on leucocyte functions: an immunoregulatory model for the hydralazine-induced lupus-like syndrome.
Topics: Concanavalin A; Humans; Hydralazine; In Vitro Techniques; Isoniazid; Leukocytes; Luminescent Measure | 1985 |
Systemic vasculitis resembling periarteritis nodosa in the lupus-like syndrome induced by hydralazine.
Topics: Adult; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Polyarteritis Nodosa; Vasculitis | 1987 |
Antibodies to the five histones and poly(adenosine diphosphate-ribose) in drug induced lupus: implications for pathogenesis.
Topics: Antibodies, Antinuclear; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Nucleoside Di | 1987 |
Fatal hydralazine-induced systemic lupus erythematosus.
Topics: Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Middle Aged | 1988 |
Neutrophilic dermatosis (Sweet's syndrome). Association with a hydralazine-induced lupus syndrome.
Topics: Drug Eruptions; Female; Fever; Humans; Hydralazine; Leukocytosis; Lupus Erythematosus, Systemic; Mid | 1986 |
Erythrocyte complement receptor type 1 (CR1) expression and circulating immune complex (CIC) levels in hydralazine-induced SLE.
Topics: Antigen-Antibody Complex; England; Erythrocytes; Female; Humans; Hydralazine; Longitudinal Studies; | 1987 |
[Primary investigation of drug-induced lupus].
Topics: Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Phenytoin | 1988 |
Interaction of nucleophilic compounds with complement component C4.
Topics: Animals; Chemical Phenomena; Chemistry; Complement C4; Complement C4a; Disease Models, Animal; Guine | 1988 |
Acute laryngeal stridor with respiratory arrest in drug induced systemic lupus erythematosus.
Topics: Aged; Cranial Nerve Diseases; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Paralysis; | 1988 |
Influence of long-term treatment with hydrazinophthalazines on the activity of lysosomal exoglycosidases in rat tissues.
Topics: Animals; Antibodies, Anti-Idiotypic; Disease Models, Animal; Glycoside Hydrolases; Hydralazine; Hydr | 1988 |
Hydralazine sensitivity: clinical features, autoantibody changes and HLA-DR phenotype.
Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Captopril; Drug Hypersensitivity; Female; HLA-DR | 1987 |
Side-effects in long-term treatment with hydralazine.
Topics: Aged; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; | 1986 |
[Procainamide- and hydralazine-induced antinuclear antibodies in Japanese].
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Asian People; Female; Humans; Hydralazine; | 1987 |
Antiguanosine antibodies: a new marker for procainamide-induced systemic lupus erythematosus.
Topics: Adult; Aged; Antibodies, Antinuclear; DNA, Single-Stranded; Female; Fluorescent Antibody Technique; | 1986 |
Cadralazine did not produce the SLE-syndrome when hydralazine did.
Topics: Adult; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Pyridazines | 1987 |
Laryngeal manifestations of drug induced lupus.
Topics: Female; Hoarseness; Humans; Hydralazine; Hypertension; Laryngeal Diseases; Lupus Erythematosus, Syst | 1987 |
Drug-induced lupus caused by very-low-dose hydralazine.
Topics: Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Middle Aged; Mouth Diseases; Palate; Ski | 1986 |
Danger of vasodilator therapy for pulmonary hypertension in patent foramen ovale.
Topics: Adult; Blood Pressure; Cardiomyopathies; Female; Heart Septum; Humans; Hydralazine; Hypertension, Pu | 1986 |
Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA.
Topics: Canavanine; Circular Dichroism; DNA; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Nucleic | 1986 |
Cardiac tamponade, associated with hydralazine therapy, in a patient with rapid acetylator status.
Topics: Acetylation; Cardiac Tamponade; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Middle A | 1986 |
[Adverse effects of prolonged treatment with hydralazine--a retrospective study].
Topics: Aged; Female; Glomerulonephritis; Humans; Hydralazine; Kidney; Lupus Erythematosus, Systemic; Male; | 1986 |
IgG subclasses of autoantibodies in systemic lupus erythematosus, Sjogren's syndrome, and drug-induced autoimmunity.
Topics: Antibodies, Monoclonal; Autoantibodies; Autoimmune Diseases; DNA; Enzyme-Linked Immunosorbent Assay; | 1986 |
Pulmonary hypertension in hydralazine induced systemic lupus erythematosus: association with C4 null allele.
Topics: Alleles; Female; HLA Antigens; HLA-C Antigens; Humans; Hydralazine; Hypertension, Pulmonary; Lupus E | 1986 |
Hydralazine binds covalently to complement component C4. Different reactivity of C4A and C4B gene products.
Topics: Complement C4; Complement C4a; Complement C4b; Female; Humans; Hydralazine; Lupus Erythematosus, Sys | 1985 |
Drug-induced lupus. Genetic, clinical, and laboratory features.
Topics: Aged; Antibodies, Antinuclear; Diagnosis, Differential; Humans; Hydralazine; Immunoglobulins; Lupus | 1985 |
The diagnostic value of antihistone antibodies in drug-induced lupus erythematosus.
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Child; Disopyramide; Female; Fluor | 1985 |
Hydralazine induced lupus syndrome with eye disease.
Topics: Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Middle Aged; Retinitis; Sy | 1985 |
Lupus after six years of mild hypertension.
Topics: Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Middle Aged; Time Factors | 1985 |
Hydralazine--is there a safe dose?
Topics: Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Syndrome | 1985 |
Hydralazine and isoniazid reduce the formation of soluble immune complexes by complement.
Topics: Antigen-Antibody Complex; Complement C3; Complement C4; Complement System Proteins; Humans; Hydralaz | 1985 |
Pulmonary hypertension in systemic lupus erythematosus.
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension, Pulmona | 1985 |
[Lupus erythematosus syndrome in the mouse].
Topics: Animals; Antibodies, Antinuclear; Female; Hydralazine; Kidney; Lupus Erythematosus, Discoid; Lupus E | 1971 |
[Drug-induced lupus erythematosus disseminatus].
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Antihypert | 1972 |
Systemic lupus erythematosus following prolonged treatment with hydralazine.
Topics: Blood Cell Count; Fluorescent Antibody Technique; Hemoglobinometry; Humans; Hydralazine; Hypertensio | 1971 |
Hydralazine-induced Lupoid syndrome. Biochemical and immunological studies.
Topics: Adult; Biopsy; Blood Sedimentation; Chemical Precipitation; Complement System Proteins; DNA; Fluores | 1974 |
Connective-tissue effects of drugs causing lupoid syndrome.
Topics: Animals; Carbon Radioisotopes; Chick Embryo; Chlorpromazine; Collagen; Depression, Chemical; Glucosa | 1974 |
Drug-induced autoimmune disease.
Topics: Acetyltransferases; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Binding Site | 1974 |
Drug-induced lupus erythematosus syndrome. Immuno-pathological, electronmicroscopical and serological studies.
Topics: Adult; Animals; Antibodies, Antinuclear; Biopsy; Complement Fixation Tests; Female; Fluorescent Anti | 1974 |
Letter: Aetiology of systemic lupus erythematosus.
Topics: Acetylation; Antibody Formation; DNA; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; | 1974 |
Experimental "hydralazine erythematodes" of the guinea pig.
Topics: Adrenal Glands; Alpha-Globulins; Animals; Blood Proteins; Cartilage; Erythrocytes; Eye; Female; Freu | 1967 |
[Prolonged administration of hydralazine in the guinea pig. Serologic and clinico-pathologic changes].
Topics: Animals; Antibodies, Anti-Idiotypic; Antibody Formation; Cell Nucleus; Dogs; Female; Fluorescent Ant | 1968 |
Diagnostic import of virus-like particles in the glomerular endothelium of patients with systemic lupus erythematosus.
Topics: Adult; Aged; Biopsy; Cytoplasm; Female; Humans; Hydralazine; Inclusion Bodies, Viral; Kidney; Kidney | 1970 |
[Possible causes of drug induced side effects in elderly people].
Topics: Aged; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Geriatrics; Humans; Hy | 1973 |
The interaction of lupus-inducing drugs with deoxyribonucleic acid.
Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immu | 1974 |
Drug-induced arthritis.
Topics: Acute Disease; Anticoagulants; Antihypertensive Agents; Arteritis; Arthritis; Barbiturates; Contrace | 1974 |
Immune responses to hydralazine and nuclear antigens in hydralazine-induced lupus erythematosus.
Topics: Adult; Antibodies, Antinuclear; Antibody Formation; Complement Fixation Tests; DNA; Drug Hypersensit | 1972 |
[Iatrogenic lupus: current status of the question. I. Clinical study and main drugs responsible].
Topics: Antibodies, Antinuclear; Contraceptives, Oral; Diagnosis, Differential; Humans; Hydralazine; Iatroge | 1972 |
Medical grand rounds--from the Medical College of Virginia. Drug-induced lupus erythematosus.
Topics: Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Disease Susceptibility; DNA; DNA, Single-Strand | 1974 |
Studies on drug induced lupus erythematosus in mice. I. Drug induced antinuclear antibodies (ANA).
Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Antibody Formation; Chlorthalidone; Coombs T | 1972 |
Studies on drug-induced lupus erythematosus in mice. II. Drug-induced smooth muscle and skeletal muscle antibodies.
Topics: Animals; Antibody Formation; Autoantibodies; Cell Membrane; Chlorthalidone; Fluorescent Antibody Tec | 1973 |
[A difficult diagnosis?].
Topics: Aged; Arthritis, Rheumatoid; Diagnosis, Differential; Female; Humans; Hydralazine; Hypertension; Lup | 1972 |
Pericardial tamponade: a major presenting manifestation of hydralazine-induced lupus syndrome.
Topics: Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Hydralazine; Lupus Erythematosus, Sy | 1973 |
Drug-induced lupus erythematosus.
Topics: Antibodies; Cell Membrane; DNA; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythem | 1973 |
[Medicaments as iatrogenic factors in the onset of lupoid syndromes].
Topics: Adolescent; Adult; Anticonvulsants; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythe | 1974 |
Drug-induced lupus syndrome.
Topics: Acetylation; Anticonvulsants; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; | 1974 |
Antinuclear antibodies following hydralazine toxicity.
Topics: Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Drug Hypersensitivity; Female; Humans; Hydrala | 1967 |
Immunological studies of collagens modified by reaction with hydralazine.
Topics: Animals; Antibody Formation; Autoantibodies; Collagen; Complement Fixation Tests; Cross Reactions; H | 1972 |
Pulmonary infiltrations during dihydralazine treatment in a slow isoniazid-inactivator.
Topics: Diagnosis, Differential; Half-Life; Humans; Hydralazine; Hypertension; Isoniazid; Lung; Lung Disease | 1972 |
Immunologic concepts of light reactions in lupus erythematosus and polymorphous light eruptions. I. The mechanism of action of hydroxychloroquine.
Topics: Antibodies, Antinuclear; Autoantibodies; Chloroquine; DNA; Erythema; Humans; Hydralazine; Hydroxychl | 1967 |
Induction by isoniazid and hydrallazine of antinuclear factors in mice.
Topics: Age Factors; Animals; Antibodies, Antinuclear; Autoantibodies; Female; Hydralazine; Isoniazid; Lupus | 1968 |
Antibodies to nucleoprotein and to hydrazide-altered soluble nucleoprotein in tuberculous patients receiving isoniazid.
Topics: Adult; Age Factors; Animals; Antigens; Autoantibodies; Cattle; Child; Complement Fixation Tests; DNA | 1969 |
Drug-induced lupus syndromes.
Topics: Anticonvulsants; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemi | 1970 |
[Activation of lupus erythematosus disseminatus caused by drugs].
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic | 1967 |
Chronic toxicity of carboethoxyphthalazinohydrazine and its influence on the excretion of 5-hydroxyindoleacetic acid and the activity of 5-htp-decarboxylase in white rats.
Topics: Animals; Anura; Aromatic Amino Acid Decarboxylase Inhibitors; Culture Techniques; Dopa Decarboxylase | 1968 |
Effect of hydrazinophthalazines on the serum glycoprotein levels. I. Effect of hydralazine.
Topics: Animals; Blood Proteins; Female; Glycoproteins; Hexosamines; Hexoses; Hydralazine; Lupus Erythematos | 1968 |
Drug-induced systemic lupus erythematosus.
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide | 1969 |
[The pathogenesis of systemic lupus erythematosus (experimental research)].
Topics: Animals; Guinea Pigs; Humans; Hydralazine; Lupus Erythematosus, Systemic; Rabbits | 1965 |
Hydralazine (Apresoline) lupus with fatal renal failure.
Topics: Aged; Anemia, Pernicious; Blood; Female; Humans; Hydralazine; In Vitro Techniques; Kidney Diseases; | 1966 |
Drug-induced systemic lupus erythematosus. Primidone as a possible cause.
Topics: Electroencephalography; Epilepsy; Female; Humans; Hydralazine; Hydroxychloroquine; Lupus Erythematos | 1966 |