hydralazine has been researched along with Kidney Diseases in 49 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To compare the effects of captopril with more conventional drugs on proteinuria and progression of renal disease, we conducted a prospective, 18-month study in 42 proteinuric (> 500 mg/day) NIDDM and, for comparison, in 31 nondiabetic patients with a variety of renal diseases (NDRD)." | 9.08 | Effect of long-term therapy with captopril on proteinuria and renal function in patients with non-insulin-dependent diabetes and with non-diabetic renal diseases. ( Campese, VM; Huang, TP; Liou, HH, 1995) |
| " In this study, we have evaluated the potential of one such agent under study, namely hydralazine, which was shown earlier to enhance hypoxia inducible factor-1α (HIF-1α) levels in experimental animal systems." | 7.75 | Hypoxic pre-conditioning in a rat renal ischemia model: an evaluation of the use of hydralazine. ( Chander, P; Choudhury, M; Dorai, T; Grasso, M; Michels, C, 2009) |
| "Renal cell carcinoma and hydralazine drug therapy has each been reported as rare associations with pauci-immune renal vasculitis." | 7.72 | P-ANCA positive renal vasculitis in association with renal cell carcinoma and prolonged hydralazine therapy. ( Jeffrey, RF; Leeds, J; Norris, JH, 2003) |
| " Immune complex glomerulonephritis has been demonstrated in a few cases of SLE following procainamide or anticonvulsant therapy but has not been documented in association with hydralazine-induced SLE despite the recognition of this syndrome 30 years ago." | 7.67 | Immune complex glomerulonephritis in hydralazine-induced SLE. ( Harrington, JT; Levey, AS; Pinn, VW; Shapiro, KS, 1984) |
| " To compare the effects of captopril with more conventional drugs on proteinuria and progression of renal disease, we conducted a prospective, 18-month study in 42 proteinuric (> 500 mg/day) NIDDM and, for comparison, in 31 nondiabetic patients with a variety of renal diseases (NDRD)." | 5.08 | Effect of long-term therapy with captopril on proteinuria and renal function in patients with non-insulin-dependent diabetes and with non-diabetic renal diseases. ( Campese, VM; Huang, TP; Liou, HH, 1995) |
| " In this study, we have evaluated the potential of one such agent under study, namely hydralazine, which was shown earlier to enhance hypoxia inducible factor-1α (HIF-1α) levels in experimental animal systems." | 3.75 | Hypoxic pre-conditioning in a rat renal ischemia model: an evaluation of the use of hydralazine. ( Chander, P; Choudhury, M; Dorai, T; Grasso, M; Michels, C, 2009) |
| "We investigated whether gender differences in renal damage in DOCA-salt hypertension are associated with effects of ovarian hormones and/or endothelin-1 (ET-1)." | 3.73 | Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats. ( Callera, GE; Carvalho, MH; Fortes, ZB; Montezano, AC; Mota, AL; Nigro, D; Tostes, RC; Zorn, TM, 2005) |
| "Renal cell carcinoma and hydralazine drug therapy has each been reported as rare associations with pauci-immune renal vasculitis." | 3.72 | P-ANCA positive renal vasculitis in association with renal cell carcinoma and prolonged hydralazine therapy. ( Jeffrey, RF; Leeds, J; Norris, JH, 2003) |
| "To evaluate the relation of tissue-localized angiotensin II (Ang II) concentration with cardiac hypertrophy and glomerulosclerosis in Tsukuba hypertensive mice (THM) carrying both human renin and angiotensinogen genes." | 3.70 | Tissue-localized angiotensin II enhances cardiac and renal disorders in Tsukuba hypertensive mice. ( Fukamizu, A; Ishikawa, K; Kai, T; Kurooka, A; Murakami, K; Shimada, S; Sugimura, K; Takenaka, T, 1998) |
| " The role of the renin-angiotensin system (RAS) in cardiac hypertrophy and nephropathy was examined in Tsukuba hypertensive mice (THM) carrying both human renin and angiotensinogen genes." | 3.70 | Renin-angiotensin system stimulates cardiac and renal disorders in Tsukuba hypertensive mice. ( Ishikawa, K; Kai, T; Kurooka, A; Shimada, S; Sugimura, K, 1999) |
| " Immune complex glomerulonephritis has been demonstrated in a few cases of SLE following procainamide or anticonvulsant therapy but has not been documented in association with hydralazine-induced SLE despite the recognition of this syndrome 30 years ago." | 3.67 | Immune complex glomerulonephritis in hydralazine-induced SLE. ( Harrington, JT; Levey, AS; Pinn, VW; Shapiro, KS, 1984) |
| "Aliskiren treatment almost completely suppressed angiotensin I and resulted in lower angiotensin II concentration than ramipril treatment." | 1.40 | Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading. ( Ayuzawa, N; Fujita, T; Ishizawa, K; Kawarazaki, W; Nagase, M; Takeuchi, M; Ueda, K; Yoshida, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (65.31) | 18.7374 |
| 1990's | 5 (10.20) | 18.2507 |
| 2000's | 4 (8.16) | 29.6817 |
| 2010's | 7 (14.29) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Matsuyama, T | 1 |
| Ohashi, N | 1 |
| Aoki, T | 1 |
| Ishigaki, S | 1 |
| Isobe, S | 1 |
| Sato, T | 1 |
| Fujikura, T | 1 |
| Kato, A | 1 |
| Miyajima, H | 1 |
| Yasuda, H | 1 |
| Baloch, NU | 1 |
| Ibeabuchi, AN | 1 |
| Yoshida, S | 1 |
| Ishizawa, K | 1 |
| Ayuzawa, N | 1 |
| Ueda, K | 1 |
| Takeuchi, M | 1 |
| Kawarazaki, W | 1 |
| Fujita, T | 1 |
| Nagase, M | 1 |
| Michels, C | 1 |
| Dorai, T | 1 |
| Chander, P | 1 |
| Choudhury, M | 1 |
| Grasso, M | 1 |
| Helle, F | 1 |
| Iversen, BM | 1 |
| Chatziantoniou, C | 1 |
| Leelahavanichkul, A | 1 |
| Yan, Q | 1 |
| Hu, X | 1 |
| Eisner, C | 1 |
| Huang, Y | 1 |
| Chen, R | 1 |
| Mizel, D | 1 |
| Zhou, H | 1 |
| Wright, EC | 1 |
| Kopp, JB | 1 |
| Schnermann, J | 1 |
| Yuen, PS | 1 |
| Star, RA | 1 |
| Landgraf, SS | 1 |
| Wengert, M | 1 |
| Silva, JS | 1 |
| Zapata-Sudo, G | 1 |
| Sudo, RT | 1 |
| Takiya, CM | 1 |
| Pinheiro, AA | 1 |
| Caruso-Neves, C | 1 |
| Azegami, T | 1 |
| Sasamura, H | 1 |
| Hayashi, K | 1 |
| Itoh, H | 1 |
| Sugiyama, F | 1 |
| Kobayashi, N | 1 |
| Ishikawa, M | 1 |
| Onoda, S | 1 |
| Ishimitsu, T | 1 |
| Norris, JH | 1 |
| Leeds, J | 1 |
| Jeffrey, RF | 1 |
| QUINZANI, F | 1 |
| GARDNER, DL | 1 |
| WERKOE, L | 1 |
| MIHAILESCU, VV | 1 |
| CLEJ, V | 1 |
| ENESCU, R | 1 |
| SBENGHE, S | 1 |
| SARLES, HE | 1 |
| HERRING, ME | 1 |
| WATSON, TF | 1 |
| GREGORY, RL | 1 |
| REMMERS, AR | 1 |
| MCQUIGGAN, MC | 1 |
| OLIVER, WJ | 1 |
| LITTLER, ER | 1 |
| CERNY, JC | 1 |
| SKINNER, DG | 1 |
| HAYES, MA | 1 |
| REUBI, F | 1 |
| GOSSWEILER, N | 1 |
| GUERTLER, R | 1 |
| HUBER, A | 1 |
| SCHMID, M | 1 |
| Montezano, AC | 1 |
| Callera, GE | 1 |
| Mota, AL | 1 |
| Fortes, ZB | 1 |
| Nigro, D | 1 |
| Carvalho, MH | 1 |
| Zorn, TM | 1 |
| Tostes, RC | 1 |
| Thiele, KG | 1 |
| Muehrcke, RC | 1 |
| Berning, H | 1 |
| DeSwarte, RD | 1 |
| Shapiro, KS | 1 |
| Pinn, VW | 1 |
| Harrington, JT | 1 |
| Levey, AS | 1 |
| Burdmann, EA | 1 |
| Andoh, TF | 1 |
| Nast, CC | 1 |
| Evan, A | 1 |
| Connors, BA | 1 |
| Coffman, TM | 1 |
| Lindsley, J | 1 |
| Bennett, WM | 1 |
| Liou, HH | 1 |
| Huang, TP | 1 |
| Campese, VM | 1 |
| Kai, T | 2 |
| Shimada, S | 2 |
| Sugimura, K | 2 |
| Kurooka, A | 2 |
| Takenaka, T | 1 |
| Fukamizu, A | 1 |
| Murakami, K | 1 |
| Ishikawa, K | 2 |
| Suganami, T | 1 |
| Mukoyama, M | 1 |
| Sugawara, A | 1 |
| Mori, K | 1 |
| Nagae, T | 1 |
| Kasahara, M | 1 |
| Yahata, K | 1 |
| Makino, H | 1 |
| Fujinaga, Y | 1 |
| Ogawa, Y | 1 |
| Tanaka, I | 1 |
| Nakao, K | 1 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Markenson, JA | 1 |
| Sherman, RL | 1 |
| Woods, JR | 1 |
| Brinkman, CR | 1 |
| Franks, PJ | 1 |
| Hartley, K | 1 |
| Bulpitt, PF | 1 |
| Bulpitt, CJ | 1 |
| Rambausek, M | 1 |
| Ritz, E | 1 |
| Mall, G | 1 |
| Mehls, O | 1 |
| Katus, H | 1 |
| Anderson, S | 1 |
| Rennke, HG | 1 |
| Brenner, BM | 1 |
| Grausz, H | 1 |
| Earley, LE | 1 |
| Stephens, BG | 1 |
| Lee, JC | 1 |
| Hopper, J | 1 |
| Groover, ME | 1 |
| Fulghum, JE | 1 |
| Simpson, WG | 1 |
| Abella, R | 1 |
| Blondeel, NJ | 1 |
| Roguska, J | 1 |
| Walker, C | 1 |
| Simon, NM | 1 |
| Del Greco, F | 1 |
| Arnold, OH | 1 |
| Amery, A | 1 |
| Fagard, R | 1 |
| Misotten, A | 1 |
| Vrcelj, S | 1 |
| Wilber, JA | 1 |
| Rorive, G | 1 |
| Rahill, WJ | 1 |
| Rubin, MI | 1 |
| Filipecki, S | 1 |
| Wocial, B | 1 |
| Pruszyński, B | 1 |
| Rajszys, R | 1 |
| Spechtmeyer, H | 1 |
| Krees, SV | 1 |
| Wolff, FW | 1 |
| Nestor, G | 1 |
| Beroniade, V | 1 |
| Tutunaru, M | 1 |
| Vertes, V | 1 |
| Cangiano, JL | 1 |
| Berman, LB | 1 |
| Gould, A | 1 |
| White, AB | 1 |
| Onesti, G | 1 |
| Tretenhahn, W | 1 |
1 review available for hydralazine and Kidney Diseases
| Article | Year |
|---|---|
Prazosin: a review of its pharmacological properties and therapeutic efficacy in hypertension.
Topics: Animals; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Eruptions; Dru | 1977 |
2 trials available for hydralazine and Kidney Diseases
| Article | Year |
|---|---|
Effect of long-term therapy with captopril on proteinuria and renal function in patients with non-insulin-dependent diabetes and with non-diabetic renal diseases.
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Ne | 1995 |
Prazosin: a review of its pharmacological properties and therapeutic efficacy in hypertension.
Topics: Animals; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Eruptions; Dru | 1977 |
47 other studies available for hydralazine and Kidney Diseases
| Article | Year |
|---|---|
Circadian rhythm of the intrarenal renin-angiotensin system is caused by glomerular filtration of liver-derived angiotensinogen depending on glomerular capillary pressure in adriamycin nephropathy rats.
Topics: Angiotensinogen; Animals; Circadian Rhythm; Doxorubicin; Glomerular Filtration Rate; Hydralazine; Hy | 2021 |
Hydralazine-induced MPO-ANCA Renal-Limited Vasculitis Masquerading as Lupus Nephritis.
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Diagnosis, Differential; Fema | 2018 |
Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading.
Topics: Albuminuria; Amides; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiot | 2014 |
Hypoxic pre-conditioning in a rat renal ischemia model: an evaluation of the use of hydralazine.
Topics: Animals; Blood Urea Nitrogen; Disease Models, Animal; Hydralazine; Hypoxia; Hypoxia-Inducible Factor | 2009 |
Losartan increases NO release in afferent arterioles during regression of L-NAME-induced renal damage.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Blood Pressur | 2010 |
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertens | 2010 |
Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Collagen; Cyclic AMP-Dependent Protein | 2011 |
Vaccination against the angiotensin type 1 receptor for the prevention of L-NAME-induced nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Enzyme Inhibit | 2012 |
Renoprotective mechanisms of telmisartan on renal injury and inflammation in SHRSP.Z-Leprfa/IzmDmcr rats.
Topics: Animals; Benzimidazoles; Benzoates; Cell Cycle Proteins; Desmin; Epithelial-Mesenchymal Transition; | 2013 |
P-ANCA positive renal vasculitis in association with renal cell carcinoma and prolonged hydralazine therapy.
Topics: Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Carcinoma, Renal Cell; Humans; Hydr | 2003 |
[Hydrazinophthalazine compounds in the treatment of hypertension in obstetrics and gynecology].
Topics: Female; Gynecology; Humans; Hydralazine; Hypertension; Kidney Diseases; Obstetrics; Pregnancy; Pregn | 1956 |
Lesions in the hypertensive rat kidney produced by hydralazine.
Topics: Animals; Hydralazine; Hypertension; Kidney Diseases; Rats | 1958 |
[HYPERTENSION].
Topics: Cerebral Hemorrhage; Diuretics; Ganglionic Blockers; Heart Arrest; Hydralazine; Hypertension; Kidney | 1963 |
[CONSIDERATIONS ON THE RENAL SIDE-EFFECTS DURING TREATMENT OF ARTERIAL HYPERTENSION].
Topics: Bretylium Compounds; Chlorothiazide; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; K | 1964 |
THE NEPHROTIC SYNDROME DUE TO PRE-ECLAMPTIC NEPHROPATHY; REPORT OF A CASE.
Topics: Blood Pressure; Blood Pressure Determination; Drug Therapy; Female; Humans; Hydralazine; Kidney Dise | 1964 |
HEMOLYTIC UREMIC SYNDROME.
Topics: Acute Kidney Injury; Anemia, Hemolytic; Child; Diagnosis; Dialysis; Diarrhea; Drug Therapy; Glomerul | 1965 |
EFFECT OF STAPHYLOCOCCAL TOXIN ON RENAL FUNCTION: IRREVERSIBLE SHOCK.
Topics: Angiotensins; Antitoxins; Dogs; Hydralazine; Hypotension; Kidney Diseases; Kidney Function Tests; Pa | 1965 |
[THE DETERMINATION OF THE RENAL BLOOD FLOW BY MEANS OF A METHOD OF DILUTION].
Topics: Anuria; Blood Flow Velocity; Dye Dilution Technique; Glomerulonephritis; Humans; Hydralazine; Kidney | 1964 |
Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats.
Topics: Animals; Dansyl Compounds; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Estrogens; Fe | 2005 |
[Kidney diseases caused by drugs].
Topics: Acute Kidney Injury; Adult; Anemia; Arthritis, Rheumatoid; Dextrans; Drug-Related Side Effects and A | 1967 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons | 1984 |
Immune complex glomerulonephritis in hydralazine-induced SLE.
Topics: Aged; Arteritis; Female; Glomerulonephritis; Humans; Hydralazine; Immune Complex Diseases; Kidney Di | 1984 |
Prevention of experimental cyclosporin-induced interstitial fibrosis by losartan and enalapril.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Cyclosporine; Enalapril; Furosemide; Hydralazine; Imida | 1995 |
Tissue-localized angiotensin II enhances cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cat | 1998 |
Renin-angiotensin system stimulates cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Humans; Hydralazine; Hyperte | 1999 |
Overexpression of brain natriuretic peptide in mice ameliorates immune-mediated renal injury.
Topics: Albuminuria; Animals; Antihypertensive Agents; Blood Pressure; Chemokine CCL2; Complement C3; Glomer | 2001 |
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide | 1979 |
The treatment of gestational hypertension.
Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype | 1975 |
Risk of serious morbidity associated with hydralazine versus methyldopa treatment in hypertensive patients.
Topics: Cardiovascular Diseases; Female; Humans; Hydralazine; Hypertension; Kidney Diseases; Male; Medical R | 1991 |
Myocardial hypertrophy in rats with renal insufficiency.
Topics: Adenosine Triphosphatases; Animals; Blood Pressure; Blood Transfusion; Calcium; Cardiomegaly; Hydral | 1985 |
Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Glomerular Filtration Rate; Hydralazin | 1986 |
Diagnostic import of virus-like particles in the glomerular endothelium of patients with systemic lupus erythematosus.
Topics: Adult; Aged; Biopsy; Cytoplasm; Female; Humans; Hydralazine; Inclusion Bodies, Viral; Kidney; Kidney | 1970 |
Arterial hypertension--northwest Florida public health survey. II. Diagnosis and treatment.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Chlorothiazide; Diuretics | 1974 |
Periodic dialysis in terminal uremia.
Topics: Adolescent; Adult; Anemia; Arthritis; Child; Female; Gastrointestinal Hemorrhage; Glaucoma; Glomerul | 1967 |
[Therapy of arterial hypertension. Results, possibilities, methods].
Topics: Adrenergic beta-Antagonists; Cerebrovascular Circulation; Coronary Disease; Diet; Diuretics; Electri | 1970 |
[Indications of antihypertensive treatment in non-malignant hypertension].
Topics: Antihypertensive Agents; Aortic Aneurysm; Benzothiadiazines; Cerebrovascular Disorders; Coronary Dis | 1974 |
[Arterial hypertension in elderly persons].
Topics: Aged; Central Nervous System Diseases; Coronary Disease; Humans; Hydralazine; Hypertension; Kidney D | 1972 |
The management of hypertension during pregnancy.
Topics: Adolescent; Adult; Blood Pressure; Clinical Laboratory Techniques; Diagnosis, Differential; Dihydrox | 1972 |
[Hypertension of renal origin].
Topics: Clonidine; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydralazine; Hypertension, Renal; Ki | 1973 |
Hypertension in infantile polycystic renal disease. The importance of early recognition and treatment of severe hypertension in polycystic renal disease.
Topics: Aluminum; Child, Preschool; Glomerular Filtration Rate; Humans; Hydralazine; Hydroxides; Hypertensio | 1972 |
[Effect of dihydralazine on renin activity in hypertensive patients].
Topics: Adult; Female; Humans; Hydralazine; Hypertension; Kidney Diseases; Male; Middle Aged; Renal Artery O | 1972 |
Some effects of hydralazine on hypertensive patients with impaired kidney function.
Topics: Animals; Glomerular Filtration Rate; Humans; Hydralazine; Hypertension; Injections, Intravenous; Kid | 1968 |
[Secondary effects of hypotensive drugs in arterial hypertension of renal origin].
Topics: Adult; Antihypertensive Agents; Female; Guanethidine; Humans; Hydralazine; Hypertension, Renal; Kidn | 1970 |
Hypertension in end-stage renal disease.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Black People; Blood Pressure; Body Weight; Chronic | 1969 |
Hydralazine (Apresoline) lupus with fatal renal failure.
Topics: Aged; Anemia, Pernicious; Blood; Female; Humans; Hydralazine; In Vitro Techniques; Kidney Diseases; | 1966 |
Renal pharmacodynamics of antihypertensive drugs: clinical applications.
Topics: Glomerular Filtration Rate; Guanethidine; Humans; Hydralazine; Hypertension; Kidney Diseases; Methyl | 1966 |
[The treatment of hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Child; Child, Preschool; Coronar | 1966 |