hydralazine has been researched along with Ischemia in 12 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Streptozotocin-induced diabetic mice were administered with either aliskiren (5 or 25 mg/kg/day) using an osmotic pump or hydralazine (2 or 10 mg/kg/day) given in drinking water for two weeks prior to a hind-limb ischemia surgery." | 7.81 | Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism. ( Chang, TT; Chen, JS; Chen, JW; Huang, PH; Lin, CP; Lin, LY; Lin, SJ; Wu, TC, 2015) |
| " In this study, we have evaluated the potential of one such agent under study, namely hydralazine, which was shown earlier to enhance hypoxia inducible factor-1α (HIF-1α) levels in experimental animal systems." | 7.75 | Hypoxic pre-conditioning in a rat renal ischemia model: an evaluation of the use of hydralazine. ( Chander, P; Choudhury, M; Dorai, T; Grasso, M; Michels, C, 2009) |
| " To determine if the TI injury accompanying cyclosporine A (CsA) nephropathy was associated with accelerated apoptosis and ischemia, we treated rats for five weeks with CsA with or without losartan (to block angiotensin II type 1 receptor), or hydralazine/furosemide (H/F) (protocol #1)." | 7.70 | Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis. ( Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE, 1998) |
| "Pretreatment with hydralazine (0." | 5.27 | Protective effects of hydralazine in a renal ischemia model in the rat. ( Agnello, A; Hirkaler, G; Rosenberger, L; Urbano, S; Vergona, RA, 1987) |
| "Streptozotocin-induced diabetic mice were administered with either aliskiren (5 or 25 mg/kg/day) using an osmotic pump or hydralazine (2 or 10 mg/kg/day) given in drinking water for two weeks prior to a hind-limb ischemia surgery." | 3.81 | Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism. ( Chang, TT; Chen, JS; Chen, JW; Huang, PH; Lin, CP; Lin, LY; Lin, SJ; Wu, TC, 2015) |
| " In this study, we have evaluated the potential of one such agent under study, namely hydralazine, which was shown earlier to enhance hypoxia inducible factor-1α (HIF-1α) levels in experimental animal systems." | 3.75 | Hypoxic pre-conditioning in a rat renal ischemia model: an evaluation of the use of hydralazine. ( Chander, P; Choudhury, M; Dorai, T; Grasso, M; Michels, C, 2009) |
| " Ischemia was induced by right femoral artery ligature in Wistar Kyoto rats (WKY) or spontaneously hypertensive rats (SHR) treated with or without angiotensin-converting enzyme inhibitor (Perindopril, 0." | 3.74 | Hypertension impairs postnatal vasculogenesis: role of antihypertensive agents. ( Cochain, C; Duriez, M; Lévy, BI; Loinard, C; Mees, B; Silvestre, JS; Vilar, J; You, D, 2008) |
| " To determine if the TI injury accompanying cyclosporine A (CsA) nephropathy was associated with accelerated apoptosis and ischemia, we treated rats for five weeks with CsA with or without losartan (to block angiotensin II type 1 receptor), or hydralazine/furosemide (H/F) (protocol #1)." | 3.70 | Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis. ( Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE, 1998) |
| "Preeclampsia is characterized by blood pressure greater than 140/90 mmHg in the second half of pregnancy." | 2.55 | Pathophysiology and Current Clinical Management of Preeclampsia. ( Amaral, LM; LaMarca, B; Owens, M; Wallace, K, 2017) |
| "Pretreatment with hydralazine (0." | 1.27 | Protective effects of hydralazine in a renal ischemia model in the rat. ( Agnello, A; Hirkaler, G; Rosenberger, L; Urbano, S; Vergona, RA, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, TT | 2 |
| Chen, JW | 2 |
| Fujita, Y | 1 |
| Ichikawa, D | 1 |
| Sugaya, T | 2 |
| Ohata, K | 1 |
| Tanabe, J | 1 |
| Inoue, K | 1 |
| Hoshino, S | 1 |
| Togo, T | 1 |
| Watanabe, M | 1 |
| Kimura, K | 1 |
| Shibagaki, Y | 1 |
| Kamijo-Ikemori, A | 1 |
| Amaral, LM | 1 |
| Wallace, K | 1 |
| Owens, M | 1 |
| LaMarca, B | 1 |
| Wu, TC | 1 |
| Huang, PH | 1 |
| Lin, CP | 1 |
| Chen, JS | 1 |
| Lin, LY | 1 |
| Lin, SJ | 1 |
| Michels, C | 1 |
| Dorai, T | 1 |
| Chander, P | 1 |
| Choudhury, M | 1 |
| Grasso, M | 1 |
| Dikow, R | 1 |
| Kihm, LP | 1 |
| Zeier, M | 1 |
| Kapitza, J | 1 |
| Törnig, J | 1 |
| Amann, K | 1 |
| Tiefenbacher, C | 1 |
| Ritz, E | 1 |
| You, D | 1 |
| Cochain, C | 1 |
| Loinard, C | 1 |
| Vilar, J | 1 |
| Mees, B | 1 |
| Duriez, M | 1 |
| Lévy, BI | 1 |
| Silvestre, JS | 1 |
| Thomas, SE | 1 |
| Andoh, TF | 1 |
| Pichler, RH | 1 |
| Shankland, SJ | 1 |
| Couser, WG | 1 |
| Bennett, WM | 1 |
| Johnson, RJ | 1 |
| Tang, AT | 1 |
| Hooper, TL | 1 |
| Sasaki, K | 1 |
| Murohara, T | 1 |
| Ikeda, H | 1 |
| Shimada, T | 1 |
| Shintani, S | 1 |
| Imaizumi, T | 1 |
| Hachida, M | 1 |
| Morton, DL | 1 |
| Vergona, RA | 1 |
| Agnello, A | 1 |
| Hirkaler, G | 1 |
| Urbano, S | 1 |
| Rosenberger, L | 1 |
1 review available for hydralazine and Ischemia
| Article | Year |
|---|---|
Pathophysiology and Current Clinical Management of Preeclampsia.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delivery, Obstetric; Endothelium, | 2017 |
11 other studies available for hydralazine and Ischemia
| Article | Year |
|---|---|
Hydralazine improves ischemia-induced neovasculogenesis via xanthine-oxidase inhibition in chronic renal insufficiency.
Topics: Allopurinol; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Enzyme Inhibitors; H | 2020 |
Angiotensin II type 1a receptor loss ameliorates chronic tubulointerstitial damage after renal ischemia reperfusion.
Topics: Angiotensin II; Animals; Blood Pressure; Hydralazine; Ischemia; Kidney; Male; Mice; Mice, Knockout; | 2021 |
Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism.
Topics: Amides; Animals; Antibodies, Monoclonal; Blood Pressure; Chemokine CXCL12; Diabetes Mellitus, Experi | 2015 |
Hypoxic pre-conditioning in a rat renal ischemia model: an evaluation of the use of hydralazine.
Topics: Animals; Blood Urea Nitrogen; Disease Models, Animal; Hydralazine; Hypoxia; Hypoxia-Inducible Factor | 2009 |
Increased infarct size in uremic rats: reduced ischemia tolerance?
Topics: Animals; Body Weight; Coronary Vessels; Heart Ventricles; Hydralazine; Imidazoles; Ischemia; Male; M | 2004 |
Hypertension impairs postnatal vasculogenesis: role of antihypertensive agents.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Bone Marrow Cells; Cell Differentiation; Disease M | 2008 |
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; Argin | 1998 |
Acute muscle damage in latissimus dorsi grafts mobilized for cardiac assist: is vasospasm an important factor?
Topics: Administration, Topical; Animals; Cardiomyoplasty; Hydralazine; Image Processing, Computer-Assisted; | 1998 |
Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis.
Topics: Angiotensin Receptor Antagonists; Animals; Blood Pressure; Capillaries; Chemokine CCL2; Endothelial | 2002 |
The protection of ischemic lung with verapamil and hydralazine.
Topics: Animals; Biopsy; Dogs; Drug Evaluation, Preclinical; Hemodynamics; Hydralazine; Ischemia; Lung; Lung | 1988 |
Protective effects of hydralazine in a renal ischemia model in the rat.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Biological Transport; Blood Pressure; Creatini | 1987 |