hydralazine has been researched along with Hypertrophy in 14 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertrophy was estimated by immunohistochemical staining of alpha-actin." | 5.29 | The role of activated vascular angiotensin II generation in vascular hypertrophy in one-kidney, one clip hypertensive rats. ( Higaki, J; Mikami, H; Morishita, R; Ogihara, T; Rakugi, H; Yu, H, 1993) |
| " The aim of this study was to compare the effects of an equivalent reduction in blood pressure produced by the angiotensin-converting enzyme (ACE) inhibitor spirapril (SPI) and an antihypertensive triple drug combination of hydralazine, reserpine and hydrochlorothiazide (HRH) on kidney function, proteinuria and renal structure in hypertensive diabetic rats." | 3.70 | Control of glomerular hyperfiltration and renal hypertrophy by an angiotensin converting enzyme inhibitor prevents the progression of renal damage in hypertensive diabetic rats. ( Armini, L; Bardelli, M; Calci, M; Campanacci, L; Candido, R; Carretta, R; Fabris, B; Fazio, M; Fischetti, F, 1999) |
| "This study was designed to investigate the effects of antihypertensive drugs on vascular hypertrophy and vascular angiotensin II in vivo in spontaneously hypertensive rats (SHR)." | 3.68 | Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat. ( Higaki, J; Mikami, H; Morishita, R; Nagano, M; Nakamura, F; Ogihara, T; Tomita, N; Yu, H, 1992) |
| " Treatment of hypertension was begun at 3 months of age with cilazapril (45 mg/kg/day), an angiotensin converting enzyme (ACE) inhibitor, or with hydralazine (18 mg/kg/day)." | 3.68 | Effects of antihypertensive therapy on mechanics of cerebral arterioles in rats. ( Baumbach, GL; Hajdu, MA; Heistad, DD, 1991) |
| "Perindopril treatment also effectively prevented the development of vascular hypertrophy; however, treatment with hydralazine and hydrochlorothiazide was not as effective despite equivalent blood pressure reduction." | 1.30 | Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27. ( Brosnan, MJ; Clark, JS; Devlin, AM; Dominiczak, AF; Mullins, JJ, 1999) |
| "Hypertrophy was estimated by immunohistochemical staining of alpha-actin." | 1.29 | The role of activated vascular angiotensin II generation in vascular hypertrophy in one-kidney, one clip hypertensive rats. ( Higaki, J; Mikami, H; Morishita, R; Ogihara, T; Rakugi, H; Yu, H, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 9 (64.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishiguro, K | 1 |
| Hayashi, K | 1 |
| Sasamura, H | 1 |
| Sakamaki, Y | 1 |
| Itoh, H | 1 |
| Johnsen, DD | 1 |
| Kacimi, R | 1 |
| Anderson, BE | 1 |
| Thomas, TA | 1 |
| Said, S | 1 |
| Gerdes, AM | 1 |
| Yu, H | 2 |
| Rakugi, H | 1 |
| Higaki, J | 2 |
| Morishita, R | 2 |
| Mikami, H | 2 |
| Ogihara, T | 2 |
| Odum, J | 1 |
| Purkiss, J | 1 |
| Naish, PF | 1 |
| Su, EJ | 1 |
| Lombardi, DM | 1 |
| Siegal, J | 1 |
| Schwartz, SM | 1 |
| Brosnan, MJ | 1 |
| Devlin, AM | 1 |
| Clark, JS | 1 |
| Mullins, JJ | 1 |
| Dominiczak, AF | 1 |
| Fabris, B | 1 |
| Candido, R | 1 |
| Armini, L | 1 |
| Fischetti, F | 1 |
| Calci, M | 1 |
| Bardelli, M | 1 |
| Fazio, M | 1 |
| Campanacci, L | 1 |
| Carretta, R | 1 |
| Nakamura, F | 1 |
| Tomita, N | 1 |
| Nagano, M | 1 |
| Baumbach, GL | 2 |
| Heistad, DD | 2 |
| Hajdu, MA | 1 |
| Canby, CA | 1 |
| Tomanek, RJ | 1 |
| Yoshida, Y | 1 |
| Kawamura, T | 1 |
| Ikoma, M | 1 |
| Fogo, A | 1 |
| Ichikawa, I | 1 |
| Jasmin, G | 1 |
| Slany, J | 1 |
2 reviews available for hydralazine and Hypertrophy
| Article | Year |
|---|---|
Drug-induced changes in mechanics and structure of cerebral arterioles.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Brain; Chronic Disease; Compliance; H | 1992 |
[Cardiac complications in hypertension].
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Diseas | 1972 |
12 other studies available for hydralazine and Hypertrophy
| Article | Year |
|---|---|
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2009 |
Protein kinase C isozymes in hypertension and hypertrophy: insight from SHHF rat hearts.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Enzyme Activation; Female; Hear | 2005 |
The role of activated vascular angiotensin II generation in vascular hypertrophy in one-kidney, one clip hypertensive rats.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 1993 |
Influence of differing classes of antihypertensive agents on mesangial kinetics following partial renal ablation in rats.
Topics: Albuminuria; Animals; Antihypertensive Agents; Biological Transport, Active; Enalapril; Glomerular M | 1994 |
Angiotensin II induces vascular smooth muscle cell replication independent of blood pressure.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Cell Division; D | 1998 |
Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive A | 1999 |
Control of glomerular hyperfiltration and renal hypertrophy by an angiotensin converting enzyme inhibitor prevents the progression of renal damage in hypertensive diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Diabetic | 1999 |
Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, A | 1992 |
Effects of antihypertensive therapy on mechanics of cerebral arterioles in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Blood Pressure; Cerebral Arteries; Ce | 1991 |
Regression of ventricular hypertrophy abolishes cardiocyte vulnerability to acute hypoxia.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Heart; Hemodynami | 1990 |
Effects of antihypertensive drugs on glomerular morphology.
Topics: Animals; Antihypertensive Agents; Enalapril; Glomerulonephritis; Glomerulosclerosis, Focal Segmental | 1989 |
Factors influencing the production of cardiomyopathies by methoxamine and metaraminol.
Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Aortic Aneurysm; Blood Pressure; Diet; Edema; F | 1969 |