Page last updated: 2024-10-28

hydralazine and Hypertension, Renal

hydralazine has been researched along with Hypertension, Renal in 134 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.

Research Excerpts

ExcerptRelevanceReference
"The effect of long-term treatment of hypertension with propranolol, alone or in combination with hydrochlorothiazide and/or dihydralazine, was investigated in 93 patients with various types of hypertension."7.66[Long-term treatment of arterial hypertension with propranolol. Combination with diuretics and dihydrazinophthalazine]. ( Ambrosio, G; Corgnati, A; Dal Palù, C; Palatini, P; Pessina, AC, 1978)
"The effect of alprenolol alone and in combination with hydralazine on plasma renin concentration has been studied in 25 patients with arterial hypertension."7.65Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension. ( Kornerup, HJ; Pedersen, EB, 1975)
" It has also been used intravenously in phaeochromocytoma, tetanus, clonidine withdrawal, and as an adjunct to halothane to produce hypotensive anaesthesia."4.76Combined alpha- and beta-receptor inhibition in the treatment of hypertension. ( Prichard, BN, 1984)
" We have previously reported that mice overexpressing angiotensinogen in renal proximal tubular cells (RPTC) develop hypertension, albuminuria, and renal injury."3.74Overexpression of angiotensinogen increases tubular apoptosis in diabetes. ( Brezniceanu, ML; Chan, JS; Chénier, I; Filep, JG; Ingelfinger, JR; Liu, F; Sachetelli, S; Wei, CC; Zhang, SL, 2008)
" However, although chronic enalapril and hydralazine protect against the loss of renal function, only enalapril limits renal growth and proteinuria, and neither significantly limits tubulointerstitial fibrosis."3.70Hypertension and renal injury in experimental polycystic kidney disease. ( Al-Nimri, MA; Anderson, S; Chapman, JG; Kelly, FJ; Kennefick, TM; Oyama, TT; Thompson, MM, 1999)
"Hydralazine (H) induces hypotension accompanied by cardiac stimulation due to activation of the arterial baroreflex."3.69Patterns of heart rate responses to hydralazine in normotensive and hypertensive rats. ( Vidrio, H, 1996)
"The effect of long-term treatment of hypertension with propranolol, alone or in combination with hydrochlorothiazide and/or dihydralazine, was investigated in 93 patients with various types of hypertension."3.66[Long-term treatment of arterial hypertension with propranolol. Combination with diuretics and dihydrazinophthalazine]. ( Ambrosio, G; Corgnati, A; Dal Palù, C; Palatini, P; Pessina, AC, 1978)
"The effect of alprenolol alone and in combination with hydralazine on plasma renin concentration has been studied in 25 patients with arterial hypertension."3.65Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension. ( Kornerup, HJ; Pedersen, EB, 1975)
"Renal fibrosis is one of the major complications associated with the development of hypertension."1.32Regression of renal vascular and glomerular fibrosis: role of angiotensin II receptor antagonism and matrix metalloproteinases. ( Boffa, JJ; Chatziantoniou, C; Dussaule, JC; Lu, Y; Placier, S; Stefanski, A, 2003)
"Prevention or retardation of diabetic nephropathy (DN) includes anti-hypertensive treatment with angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II type 1 receptor blockers (ARB) on the premises that these drugs have an added protective effect beyond their influence on BP."1.32Anti-hypertensive agents inhibit in vivo the formation of advanced glycation end products and improve renal damage in a type 2 diabetic nephropathy rat model. ( Inagi, R; Ishikawa, N; Koike, H; Kurokawa, K; Miyata, T; Mizuno, M; Nangaku, M; Sada, T; Ueda, Y; van Ypersele de Strihou, C; Yuzawa, H, 2003)
"Perindopril was associated with significantly lower AER than lacidipine, whereas lacidipine was more potent in preventing increases in ocular AVC."1.29Organ specificity of antihypertensive therapy on ocular albumin vascular clearance and albuminuria in the hypertensive diabetic rat. ( Cooper, M; Gin, T; Jerums, G; Joon, TL; Panagiotopoulos, S; Taylor, H, 1996)
" In the second protocol, young SHRs (4 weeks of age) were treated with the same dosage of hydralazine until 16 weeks of age."1.27Independence of blood pressure and locomotor hyperactivity in normotensive and genetically hypertensive rat. ( Atwater, DG; Gellis, JE; Hendley, ED; Low, WC; Whitehorn, D, 1983)
"Pretreatment with atenolol attenuated the cardiac stimulation and thereby accentuated the hypotensive effect of hydralazine, 0."1.27Interaction of atenolol with the systemic and regional hemodynamic effects of hydralazine in conscious renal hypertensive rabbits. ( Bolt, GR; Saxena, PR, 1984)
" Daily oral dosing of hydralazine (2 mg/kg/day) for 14 weeks had little or no effect on SBP, but potentiated the antihypertensive effect of SA446."1.27[Antihypertensive effects of SA446, hydralazine and the combination on renal hypertensive rats and spontaneously hypertensive rats by long-term treatment]. ( Iso, T; Nakata, K; Nishimura, K; Takada, T; Yamauchi, H, 1986)
" Nisoldipine had the lowest maximum plasma concentration and the longest elimination half-life among the four 1,4-dihydropyridines, resulting in no significant difference in the area under the plasma concentration-time curve."1.27Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs. ( Kato, H; Takata, Y, 1986)
" produced a gradual, progressive and significant fall in blood pressure which reached a maximum 3--4 h after dosing and persisted for 6--10 h."1.26Hypotensive and cardiovascular action of budralazine in unanesthetized and unrestrained dogs. ( Konno, K; Nonaka, K; Ueno, A, 1981)
"Nitrendipine was found about 20 times more potent in its antihypertensive action than hydralazine."1.26Effect of a new calcium antagonist, nitrendipine, on blood pressure and heart rate of conscious, unrestrained dogs. ( Knorr, A; Stoepel, K, 1981)
" Substantial and prolonged falls in blood pressure were observed following oral dosing with 3 mg/kg of nifedipine in renal hypertensive rats, with 10 mg/kg of nifedipine in normotensive and spontaneously hypertensive rats and with 10 mg/dg of hydralazine in all three groups of animals."1.26Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats. ( Fujie, K; Kubo, T; Misu, Y; Yamashita, M, 1981)
"Propranolol was given to 10 hypertensive patients with CGN and hypotensive effect on renal function was observed."1.25Therapy and prognosis of hypertension in chronic nephritis. ( Kajiwara, N, 1975)

Research

Studies (134)

TimeframeStudies, this research(%)All Research%
pre-1990113 (84.33)18.7374
1990's8 (5.97)18.2507
2000's12 (8.96)29.6817
2010's1 (0.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diana, GD1
Hinshaw, WB1
Lape, HE1
Bellasio, E1
Campi, A1
Di Mola, N1
Baldoli, E1
Archibald, JL1
Beardsley, DR1
Ward, TJ1
Waterfall, JF1
White, JF1
Sogawa, Y1
Nagasu, H1
Itano, S1
Kidokoro, K1
Taniguchi, S1
Takahashi, M1
Kadoya, H1
Satoh, M1
Sasaki, T1
Kashihara, N1
Kim, SM1
Eisner, C1
Faulhaber-Walter, R1
Mizel, D1
Wall, SM1
Briggs, JP1
Schnermann, J1
Grisk, O1
Rose, HJ1
Lorenz, G1
Rettig, R1
Boffa, JJ1
Lu, Y1
Placier, S1
Stefanski, A1
Dussaule, JC1
Chatziantoniou, C1
Nangaku, M1
Miyata, T1
Sada, T1
Mizuno, M1
Inagi, R1
Ueda, Y1
Ishikawa, N1
Yuzawa, H1
Koike, H1
van Ypersele de Strihou, C1
Kurokawa, K1
HEJTMANCIK, MR1
TAKEUCHI, J1
TAKEDA, T1
UCHIDA, E1
OKADA, R1
SHINTANI, F1
SANCHETTI, P1
FAVERO, S1
LONGARETTI, A1
BELSITO, F1
BRUSCA, A1
SCHRIEVER, K1
TAKATSU, T1
JAMES, JA1
FINK, CW1
SAMBHI, MP1
VENNING, EH1
BECK, JC1
BENDERLY, A1
MEIRING, PD1
Griffin, KA1
Picken, MM1
Bidani, AK1
Soto, K1
Gómez-Garre, D1
Largo, R1
Gallego-Delgado, J1
Tejera, N1
Catalán, MP1
Ortiz, A1
Plaza, JJ1
Alonso, C1
Egido, J1
Lee, TM1
Lin, MS1
Tsai, CH1
Chang, NC1
Liu, F1
Brezniceanu, ML1
Wei, CC1
Chénier, I1
Sachetelli, S1
Zhang, SL1
Filep, JG1
Ingelfinger, JR1
Chan, JS1
Westhoff, JH1
Hilgers, KF1
Steinbach, MP1
Hartner, A1
Klanke, B1
Amann, K1
Melk, A1
Michaels, RS1
Duchin, KL1
Akbar, S1
Meister, J1
Levin, NW1
Prichard, BN1
Whitehorn, D1
Atwater, DG1
Low, WC1
Gellis, JE1
Hendley, ED1
Cushman, DW1
Ondetti, MA1
Cheung, HS1
Antonaccio, MJ3
Murthy, VS1
Rubin, B2
Gomes, AS1
Sinaiko, AR1
Tobian, L1
Cohn, JN1
Formanek, G1
Amplatz, K1
Bolt, GR1
Saxena, PR1
Maeda, T1
Onoyama, K1
Omae, T2
Fujimi, S1
Konno, K1
Nonaka, K1
Ueno, A1
Knorr, A1
Stoepel, K1
Kubo, T1
Fujie, K1
Yamashita, M1
Misu, Y1
Arrigoni-Martelli, E1
Nielsen, CK1
Olsen, UB1
Petersen, HJ1
Talseth, T1
McNay, JL1
Clementi, WA1
Webb, DB1
White, JP1
Ishii, H1
Itoh, K1
Nose, T1
Gin, T1
Joon, TL1
Panagiotopoulos, S1
Cooper, M1
Taylor, H1
Jerums, G1
Vidrio, H1
Casellas, D1
Benahmed, S1
Artuso, A1
Jover, B1
Nishimura, M1
Ohtsuka, K1
Iwai, N1
Takahashi, H1
Yoshimura, M1
Matsumoto, K1
Morishita, R1
Moriguchi, A1
Tomita, N1
Yo, Y1
Nishii, T1
Nakamura, T2
Higaki, J1
Ogihara, T1
Kennefick, TM1
Al-Nimri, MA1
Oyama, TT1
Thompson, MM1
Kelly, FJ1
Chapman, JG1
Anderson, S3
Sabbatini, M1
Leonardi, A1
Testa, R1
Vitaioli, L1
Amenta, F1
Obata, J1
Takano, H1
Naito, A1
Kimura, H1
Yoshida, Y1
Shimizu, F1
Guo, DF1
Inagami, T1
Hassan, K1
Weissmam, I1
Osman, S1
Gery, R1
Oettinger, M1
Shasha, SM1
Kristal, B1
Zabicka, H1
Chrzanowski, W1
Kubala, L1
Orlowski, Z1
Dorigotti, L1
Rolandi, R1
Carpi, C1
Petty, MA1
Reid, JL1
Markenson, JA1
Sherman, RL1
Herlitz, H2
Aurell, M2
Granerus, G2
Sullivan, JM1
Horovitz, ZP1
Panasevich, RE1
Klevans, LR1
Hirkaler, G1
Kovacs, JL1
Hiwatari, M1
Satoh, K1
Taira, N1
Pessina, AC1
Corgnati, A1
Palatini, P1
Ambrosio, G1
Dal Palù, C1
Falch, DK1
Norman, N2
Adelman, RD1
Merten, D1
Vogel, J1
Goetzman, BW1
Wennberg, RP1
Cangiano, JL3
Rodriguez-Sargent, C2
Martinez-Maldonado, M2
Lam, M1
Ricanati, ES1
Khan, MA1
Kushner, I1
Munoz, AI1
Baralt, JF1
Melendez, MT1
Fleischmann, LE1
Siegler, RL1
Brinkman, CR2
Assali, NS1
Holland, NH1
Kotchen, T1
Bhathena, D1
Doyle, TJ1
McGregor, WR1
Fox, PS1
Maddison, FE1
Rodgers, RE1
Kauffman, HM1
Groover, ME1
Simpson, WE1
Fulghum, JE1
Massingham, R1
Hayden, ML1
Forsythe, WE1
Persky, L1
Sundsfjord, JA1
Stiris, G1
Kajiwara, N1
Tanaka, K1
Fukiyama, K1
Kumamoto, K1
Yamamoto, Y1
Oniki, H1
Johansson, M1
Manhem, P1
Constantine, JW1
McShane, WK1
Scriabine, A1
Hess, HJ1
Pedersen, EB1
Kornerup, HJ1
Woods, JR1
Langevitz, P1
Buskila, D1
Lee, P1
Hercz, G1
Camacho, AA1
Salgado, MC1
Krieger, EM1
Rennke, HG2
Garcia, DL1
Brenner, BM2
Yamashita, W1
Delin, K1
Hedner, T1
Loeb, AL1
Bean, BL1
Harper, SL1
Dworkin, LD1
Feiner, HD1
Randazzo, J1
Nakata, K1
Nishimura, K1
Takada, T1
Yamauchi, H1
Iso, T1
Smith, SH1
Bishop, SP1
Takata, Y1
Kato, H1
Neugarten, J1
Kaminetsky, B1
Feiner, H1
Schacht, RG1
Liu, DT1
Baldwin, DS1
Groth, H1
Vetter, H1
Achermann, R1
Kuhlmann, U1
Siegenthaler, W1
Vetter, W1
Kühns, K1
Kaufmann, W1
Brunner, H1
Hedwall, PR1
Loggie, J1
Finnerty, FA1
Freis, ED1
Teichmann, G2
Harms, R1
Wedler, B1
Rohmann, H1
Jung, D1
Wulff, E1
Fröhling, P1
Lemke, E1
Lindenau, K1
Behla, M1
Rosenthal, J1
Gottwick, M1
Hollander, W1
Kim, KE1
Onesti, G1
Swartz, C1
Robson, RD1
Povalski, HS1
Rorive, G1
Klumpp, F2
Klaus, D2
Rössler, R2
Sadowski, P2
Isdale, JM1
Thomson, PD1
Katz, S1
Dzúrik, R1
Reznícek, J1
Krídl, J1
Gittes, RF1
McLaughlin, AP1
Bennett, SP1
Levine, LS1
Siegal, EJ1
Lewy, JE1
Susin, M1
Peterson, RE1
New, MI1
Belman, AB1
Lewy, PR1
Chassin, MR1
Sulivan, JM1
Tucker, RM1
Hunt, JC1
Bock, KD1
Kirkendall, WM1
Kioschos, JM1
Brodwall, EK1
Myhre, E1
Stenbaek, O1
Baum, T1
Shropshire, AT1
Varner, LL1
Hirasawa, Y1
Omori, H1
Takahashi, Y1
Imai, H1
Takahashi, S1
Ebihara, A1
Martz, BL1
Nestor, G1
Beroniade, V1
Tutunaru, M1
Frotscher, U1
Wilbrandt, R1
Piehl, W1
Freyland, MD1
Messerschmidt, W1
Sheps, SG1
Bernsmeier, A1
Ramalho, PS1
Dollery, CT1
Pavesi, V1
Campus, G1
Ueda, H1
Yagi, S1
Kaneko, Y1
Richet, G1
Ducrot, H1
Hamburger, J1
Legrain, M1
Maxwell, M1
Péquignot, MH1
Ayers, CR1
Harris, RH1
Lefer, LG1
Vertes, V1
Berman, LB1
Gould, A1
Repetto, S1
Rezzonico, A1
Gervasini, N1
Mannick, JA1
Huvos, A1
Hollander, WE1
Hutchings, RH1
Hickman, R1
Scribner, BH1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Delaying the Progression of Diabetic Nephropathy in Pima Indians[NCT00353600]25 participants (Anticipated)Observational1994-08-19Completed
Renoprotection in Early Diabetic Nephropathy in Pima Indians[NCT00340678]Phase 3170 participants (Actual)Interventional1995-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Glomerular Volume

(NCT00340678)
Timeframe: 6 years after first treatment

Intervention*10^6 cubic microns (Mean)
Normoalbuminuria Losartan5.4
Normoalbuminuria Placebo5.6
Microalbuminuria Losartan6.4
Microalbuminuria Placebo7.0

Number of Participants With Decline in GFR

Participants were monitored for up to 6 years. This is the number of participants who had a decline in GFR to less than or equal to 60 ml/min or to half the baseline value in subjects that enter the study with a GFR of less than 120 ml/min during the time of observation. (NCT00340678)
Timeframe: Up to 6 years

Interventionparticipants (Number)
Normoalbuminuria Losartan2
Normoalbuminuria Placebo2
Microalbuminuria Losartan1
Microalbuminuria Placebo4

Reviews

9 reviews available for hydralazine and Hypertension, Renal

ArticleYear
[THERAPY OF ESSENTIAL HYPERTENSION].
    Aggiornamenti clinicoterapeutici, 1963, Volume: 4

    Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Coronary Disease; Diazoxide; Diet; Dihydr

1963
[THE GROUP OF ANTIHYPERTENSIVE DRUGS].
    Medizinische Monatsschrift, 1963, Volume: 17

    Topics: Alkaloids; Antihypertensive Agents; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertensio

1963
[DRUG THERAPY OF CIRCULATORY DISEASES].
    Naika. Internal medicine, 1964, Volume: 13

    Topics: Antihypertensive Agents; Arteriosclerosis; Bretylium Compounds; Cardiovascular Diseases; Chlorothiaz

1964
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
    Drugs, 1984, Volume: 28 Suppl 2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihyp

1984
[Long-term dialysis and its problems: hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1980, Volume: 38, Issue:6

    Topics: Humans; Hydralazine; Hypertension, Renal; Japan; Kidney Failure, Chronic; Propranolol; Renal Dialysi

1980
Physiologic and biochemical profile of hypertension for rational clinical management.
    Advances in internal medicine, 1978, Volume: 23

    Topics: Adrenal Gland Diseases; Angiotensins; Body Fluid Compartments; Chlorthalidone; Diuretics; Guanethidi

1978
The treatment of hypertension. Why, when and how.
    The American journal of medicine, 1972, Volume: 52, Issue:5

    Topics: Arteriosclerosis; Cardiovascular Diseases; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hyd

1972
Recent advances in the medical and surgical treatment of hypertension.
    The Medical clinics of North America, 1968, Volume: 52, Issue:5

    Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni

1968
Studies on patients with renal artery stenosis (the diagnostic value of plasma renin activity measurements).
    Transactions of the American Clinical and Climatological Association, 1971, Volume: 82

    Topics: Female; Humans; Hydralazine; Hypertension, Renal; Kidney Function Tests; Male; Methyldopa; Renal Art

1971

Trials

2 trials available for hydralazine and Hypertension, Renal

ArticleYear
[Diuretics and antihypertensive agents in chronic kidney insufficiency: comparison of the effects of metolazone and furosemide].
    Schweizerische medizinische Wochenschrift, 1985, Jan-12, Volume: 115, Issue:2

    Topics: Adult; Aged; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Hydralazine; Hyperten

1985
[Clinical administration of hydralazin (Depressan) in essential and renal hypertension].
    Zeitschrift fur arztliche Fortbildung, 1972, Nov-01, Volume: 66, Issue:21

    Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Humans; Hydralazine; Hypert

1972

Other Studies

123 other studies available for hydralazine and Hypertension, Renal

ArticleYear
Synthesis and antihypertensive activity of 1-amino-3,4-dihydroisoquinolines.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Hypertension, Renal; Isoquin

1977
Antihypertensives. N-1H-Pyrrol-1-yl-3-pyridazinamines.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:8

    Topics: Animals; Antihypertensive Agents; Dogs; Heart Rate; Hydralazine; Hypertension; Hypertension, Renal;

1984
synthesis and antihypertensive activity of 2-sulfonamido- and 2-sulfamido-1,3,4,6,7,11b alpha-hexahydro-2H-benzo[a]quinolizines.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cats; Female; Heart Rate; Hypertension, Renal; Iso

1983
The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Aldosterone; Animals; Antihypertensive Agents; Disease Models, Animal; Endothelium; Fibrosis; Humans

2018
Salt sensitivity of blood pressure in NKCC1-deficient mice.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:4

    Topics: Adrenergic beta-Agonists; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Circadian R

2008
Sympathetic-renal interaction in chronic arterial pressure control.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 283, Issue:2

    Topics: Animals; Animals, Newborn; Arteriosclerosis; Blood Pressure; Body Weight; Creatinine; Crosses, Genet

2002
Regression of renal vascular and glomerular fibrosis: role of angiotensin II receptor antagonism and matrix metalloproteinases.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:5

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Collagen; Enzyme

2003
Anti-hypertensive agents inhibit in vivo the formation of advanced glycation end products and improve renal damage in a type 2 diabetic nephropathy rat model.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:5

    Topics: Animals; Antihypertensive Agents; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mel

2003
Systemic hypertension. Present status of medical management.
    Texas state journal of medicine, 1962, Volume: 58

    Topics: Chlorothiazide; Ganglionic Blockers; Guanethidine; Hydralazine; Hypertension; Hypertension, Renal; R

1962
Vascular lesions in experimental renal hypertension, with special reference to effect of hypotensive treatment.
    Japanese heart journal, 1963, Volume: 4

    Topics: Arteries; Cerebral Hemorrhage; Coronary Vessels; Guanethidine; Humans; Hydralazine; Hydrochlorothiaz

1963
[CLINICAL STUDY OF A NEW COMPLEX HYPOTENSIVE DRUG COMBINATION].
    Gazzetta medica italiana, 1963, Volume: 122

    Topics: Antihypertensive Agents; Arteriosclerosis; Carbamates; Cerebrovascular Disorders; Coronary Disease;

1963
[CLINICAL RESEARCH WITH A COMPOUND HYPOTENSIVE PREPARATION (MEBUTAMATE + 1-4 DIHYDRAZINOPHTHALAZINE + DIHYDROCHLOROTHIAZIDE + POTASSIUM)].
    Gazzetta medica italiana, 1963, Volume: 122

    Topics: Antihypertensive Agents; Arteriosclerosis; Carbamates; Humans; Hydralazine; Hydrochlorothiazide; Hyp

1963
ACUTE GLOMERULONEPHRITIS.
    Clinical pediatrics, 1964, Volume: 3

    Topics: Blood Chemical Analysis; Child; Convalescence; Edema; Electrocardiography; Erythromycin; Glomerulone

1964
ALDOSTERONE SECRETION RATE AND ELECTROLYTE BALANCE STUDIES ON THREE PATIENTS WITH HYPERTENSION. INFLUENCE OF GUANETHIDINE, HYDRALAZINE AND METHYCLOTHIAZIDE.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Aldosterone; Diet, Sodium-Restricted; Diuretics; Guanethidine; Heart Diseases; Humans; Hydralazine;

1964
[TREATMENT OF HYPERTENSION DUE TO ACUTE GLOMERULONEPHRITIS WITH PARENTERAL RESERPINE AND HYDRALAZINE].
    Harefuah, 1964, Jun-01, Volume: 66

    Topics: Glomerulonephritis; Hydralazine; Hypertension; Hypertension, Renal; Infusions, Parenteral; Kidney; R

1964
EXPERIENCES WITH THE LONG-TERM USE OF METHYLDOPA ("ALDOMET") IN HYPERTENSION.
    The Medical journal of Australia, 1965, Mar-20, Volume: 1, Issue:12

    Topics: Benzothiadiazines; Blood Pressure Determination; Depression; Drug Therapy; Drug Tolerance; Glomerulo

1965
Blood pressure lability and glomerulosclerosis after normotensive 5/6 renal mass reduction in the rat.
    Kidney international, 2004, Volume: 65, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Enalapril; Glomeruloscl

2004
Tight blood pressure control decreases apoptosis during renal damage.
    Kidney international, 2004, Volume: 65, Issue:3

    Topics: Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Cell Division; Drug Therapy, Combinatio

2004
Effect of pravastatin on left ventricular mass in the two-kidney, one-clip hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Natriuretic Factor; Echocardiography; Gene Expression Regula

2006
Overexpression of angiotensinogen increases tubular apoptosis in diabetes.
    Journal of the American Society of Nephrology : JASN, 2008, Volume: 19, Issue:2

    Topics: Albuminuria; Angiotensinogen; Animals; Antihypertensive Agents; Apoptosis; bcl-2-Associated X Protei

2008
Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Antihypertensive Ag

2008
Nadolol in hypertensive patients maintained on long-term hemodialysis.
    American heart journal, 1984, Volume: 108, Issue:4 Pt 2

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Drug Therapy, Combination; Female; Furosemide; Half-Lif

1984
Independence of blood pressure and locomotor hyperactivity in normotensive and genetically hypertensive rat.
    Behavioral and neural biology, 1983, Volume: 37, Issue:2

    Topics: Animals; Blood Pressure; Hot Temperature; Humans; Hydralazine; Hyperkinesis; Hypertension; Hypertens

1983
Inhibitors of angiotensin-converting enzyme.
    Advances in experimental medicine and biology, 1980, Volume: 130

    Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitiv

1980
Hydralazine and the tourniquet test in renal vein renin sampling: a comparison.
    Radiology, 1983, Volume: 146, Issue:3

    Topics: Blood Pressure; Humans; Hydralazine; Hypertension, Renal; Hypertension, Renovascular; Renal Veins; R

1983
Interaction of atenolol with the systemic and regional hemodynamic effects of hydralazine in conscious renal hypertensive rabbits.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:1

    Topics: Animals; Atenolol; Blood Gas Analysis; Drug Interactions; Electric Conductivity; Heart Rate; Hemodyn

1984
Hypotensive and cardiovascular action of budralazine in unanesthetized and unrestrained dogs.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:7

    Topics: Animals; Antihypertensive Agents; Coronary Circulation; Dogs; Female; Heart Rate; Hemodynamics; Hydr

1981
Effect of a new calcium antagonist, nitrendipine, on blood pressure and heart rate of conscious, unrestrained dogs.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:12

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Dose-Response Relationship, Drug; Female; H

1981
Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hydralazine; Hypertension; Hypertensio

1981
N''-cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine, monohydrate (P 1134): a new, potent vasodilator.
    Experientia, 1980, Apr-15, Volume: 36, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Dose-Response Relationship, Drug; Guanidines; Heart R

1980
Route and rate of hydrallazine administration as determinants to its hypotensive effect in rabbits.
    Clinical and experimental pharmacology & physiology, 1980, Volume: 7, Issue:4

    Topics: Animals; Blood Pressure; Hydralazine; Hypertension, Renal; Injections, Intraperitoneal; Injections,

1980
Hypertension after taking hydrallazine.
    British medical journal, 1980, Jun-28, Volume: 280, Issue:6231

    Topics: Adolescent; Female; Humans; Hydralazine; Hypertension; Hypertension, Renal

1980
Different antihypertensive effects of nifedipine in conscious experimental hypertensive and normotensive rats.
    European journal of pharmacology, 1980, May-30, Volume: 64, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Heart Rate; Hydralazine; Hyp

1980
Organ specificity of antihypertensive therapy on ocular albumin vascular clearance and albuminuria in the hypertensive diabetic rat.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:2

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press

1996
Patterns of heart rate responses to hydralazine in normotensive and hypertensive rats.
    Archives of medical research, 1996,Autumn, Volume: 27, Issue:3

    Topics: Animals; Antihypertensive Agents; Baroreflex; Bradycardia; Female; Heart Rate; Hydralazine; Hyperten

1996
Candesartan and progression of preglomerular lesions in N(G)-nitro-L-arginine methyl ester hypertensive rats.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Bip

1999
Regulation of brain renin-angiotensin system by benzamil-blockable sodium channels.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Amiloride; Animals; Arginine Vasopressin; Blood Pressure; Brain; Brain Chemistry; Desoxycorticostero

1999
Prevention of renal damage by angiotensin II blockade, accompanied by increased renal hepatocyte growth factor in experimental hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals;

1999
Hypertension and renal injury in experimental polycystic kidney disease.
    Kidney international, 1999, Volume: 56, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Enalapril; Fibrosis; Hydralazine; Hypertension, Re

1999
Effect of calcium antagonists on glomerular arterioles in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:3

    Topics: Albuminuria; Animals; Arterioles; Calcium; Calcium Channel Blockers; Dihydropyridines; Hydralazine;

2000
Increased gene expression of components of the renin-angiotensin system in glomeruli of genetically hypertensive rats.
    Journal of hypertension, 2000, Volume: 18, Issue:9

    Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biph

2000
Successful pregnancy in a patient with polycystic kidney disease and advanced renal failure without prophylactic dialysis.
    Nephron, 2001, Volume: 87, Issue:1

    Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Rena

2001
[Combined treatment with hydrazinophthalazines and beta sympatholytic agents of nephrogenic hypertension].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, Dec-27, Volume: 31, Issue:52

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Female; Humans; Hyd

1976
A new antihypertensive compound: 3 hydrazino-6- [(2-hydroxypropyl)methylamino] pyridazine dihydrochloride (ISF 2123).
    Pharmacological research communications, 1976, Volume: 8, Issue:3

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Cats; Disease Models, Animal

1976
Brain catecholamines and catecholamine-synthesizing enzymes in renovascular hypertension in the rat.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Animals; Brain; Brain Chemistry; Catecholamines; Hydralazine; Hypertension, Renal; Hypertension, Ren

1978
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:10

    Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide

1979
Cyclic AMP, renal function and dihydralazine-stimulated renin secretion in hypertensive patients.
    Scandinavian journal of clinical and laboratory investigation, 1979, Volume: 39, Issue:4

    Topics: Aged; Cyclic AMP; Dihydralazine; Female; Glomerular Filtration Rate; Humans; Hydralazine; Hypertensi

1979
Influence of various antihypertensive agents on lifespan of renal hypertensive rats.
    British journal of clinical pharmacology, 1979, Volume: 7 Suppl 2

    Topics: Animals; Blood Pressure; Disease Models, Animal; Diuretics; Hydralazine; Hydrochlorothiazide; Hypert

1979
Indirect blood pressure determination by Doppler technique in renal hypertensive cats.
    The American journal of physiology, 1979, Volume: 237, Issue:6

    Topics: Animals; Blood Pressure; Blood Pressure Determination; Cats; Diastole; Hydralazine; Hypertension, Re

1979
Antihypertensive effect of nifedipine on conscious renal-hypertensive dogs.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:2

    Topics: Animals; Antihypertensive Agents; Dogs; Female; Hemodynamics; Hydralazine; Hypertension, Renal; Male

1979
[Long-term treatment of arterial hypertension with propranolol. Combination with diuretics and dihydrazinophthalazine].
    Minerva medica, 1978, Feb-11, Volume: 69, Issue:7

    Topics: Adult; Dihydralazine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydro

1978
The cardiac response to a small i.v. dose of dihydralazine, a safe drug for diagnostic tests?
    Acta medica Scandinavica, 1978, Volume: 203, Issue:5

    Topics: Adult; Blood Pressure; Cardiac Output; Coronary Vessels; Dihydralazine; Dose-Response Relationship,

1978
Nonsurgical management of renovascular hypertension in the neonate.
    Pediatrics, 1978, Volume: 62, Issue:1

    Topics: Adult; Antihypertensive Agents; Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertension, Ren

1978
Modification of experimental renal hypertension in the rat by indomethacin and hydralazine.
    The Journal of laboratory and clinical medicine, 1978, Volume: 92, Issue:4

    Topics: Animals; Disease Models, Animal; Female; Hydralazine; Hypertension, Renal; Indomethacin; Potassium;

1978
Reversal of severe renal failure in systemic sclerosis.
    Annals of internal medicine, 1978, Volume: 89, Issue:5 Pt 1

    Topics: Acute Kidney Injury; Biopsy; Female; Humans; Hydralazine; Hypertension, Renal; Kidney; Methyldopa; M

1978
Effects of antihypertensive treatment on systolic blood pressure and renin in experimental hypertension in rats.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Female; Hydralazine; Hypertension, Renal; Hyperten

1979
Arterial hypertension in infants with hydronephrosis. Report of six cases.
    American journal of diseases of children (1960), 1977, Volume: 131, Issue:1

    Topics: Blood Pressure; Female; Humans; Hydralazine; Hydronephrosis; Hypertension, Renal; Infant; Infant, Ne

1977
Management of hypertensive crisis in children.
    Pediatric annals, 1977, Volume: 6, Issue:6

    Topics: Acute Disease; Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Diazoxide; Humans; Hy

1977
Conservative management of neonatal renal artery embolism.
    Urology, 1976, Volume: 8, Issue:5

    Topics: Aortography; Blood Flow Velocity; Catheterization; Drug Therapy, Combination; Embolism; Humans; Hydr

1976
Uteroplacental hemodynamic response to antihypertensive drugs in hypertensive pregnant sheep.
    Perspectives in nephrology and hypertension, 1976, Volume: 5

    Topics: Animals; Blood Pressure; Female; Heart Rate; Hydralazine; Hypertension, Renal; Placenta; Pregnancy;

1976
Hypertension in children with chronic pyelonephritis.
    Kidney international. Supplement, 1975

    Topics: Blood Pressure; Child; Child, Preschool; Female; Humans; Hydralazine; Hypertension, Renal; Kidney; M

1975
Homotransplant renal artery stenosis.
    Surgery, 1975, Volume: 77, Issue:1

    Topics: Angiography; Benzothiadiazines; Child; Guanethidine; Humans; Hydralazine; Hypertension, Renal; Kidne

1975
The early detection and treatment of hypertension.
    Angiology, 1975, Volume: 26, Issue:1 Pt. 1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorothiazide; Diuretics; Female; Florida; Furose

1975
A comparsion of the effects of prazosin and hydrallazine on blood pressure, heart rate and plasma renin activity in conscious renal hypertensive dogs.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Furans; Hydralazine; Hypertension, Renal; Ma

1975
A case of renovascular hypertension in a 9-month-old child.
    The Journal of urology, 1975, Volume: 113, Issue:5

    Topics: Age Factors; Diazoxide; Female; Humans; Hydralazine; Hypertension, Renal; Infant; Renal Artery; Rena

1975
Effective renal plasma flow (ERPF) of the individual kidney and renal venous renin activity (RVRA) determined simultaneoulsy before and after the administration of dihydralazine in renovascular hypertension.
    Scandinavian journal of clinical and laboratory investigation, 1975, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Blood Pressure; Female; Humans; Hydralazine; Hypertension, Renal; Kidney; Kidney

1975
Therapy and prognosis of hypertension in chronic nephritis.
    Japanese circulation journal, 1975, Volume: 39, Issue:7

    Topics: Adult; Aldosterone; Angiotensin II; Blood Volume; Catecholamines; Chronic Disease; Creatinine; Extra

1975
Relationship between plasma renin activity and blood pressure response to antihypertensive agents. A proposal for management of essential and renal hypertension.
    Japanese circulation journal, 1975, Volume: 39, Issue:7

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Body Weight; Furosemide; Humans; Hydralazine; Hypert

1975
[SLE-syndrome with exophthalmus after treatment with hydralazine].
    Lakartidningen, 1975, Jan-15, Volume: 72, Issue:3

    Topics: Exophthalmos; Humans; Hydralazine; Hypertension, Renal; Lupus Erythematosus, Systemic; Male; Middle

1975
Analysis of the hypotensive action of prazosin.
    Postgraduate medicine, 1975, Volume: Spec No

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Cats; Dogs; Drug Interactions; Ele

1975
Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension.
    Acta medica Scandinavica, 1975, Volume: 198, Issue:5

    Topics: Adult; Aged; Alprenolol; Depression, Chemical; Drug Therapy, Combination; Female; Humans; Hydralazin

1975
The treatment of gestational hypertension.
    The Journal of reproductive medicine, 1975, Volume: 15, Issue:5

    Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype

1975
Scleroderma hypertensive renal crisis and the changing pattern of mortality in systemic sclerosis (scleroderma)
    Nephron, 1991, Volume: 57, Issue:1

    Topics: Adult; Captopril; Female; Humans; Hydralazine; Hypertension, Renal; Kidney; Male; Middle Aged; Minox

1991
Reversal of hyperreactivity to bradykinin in renal hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:2 Suppl

    Topics: Animals; Blood Pressure; Bradykinin; Constriction; Dose-Response Relationship, Drug; Hydralazine; Hy

1990
Short and long term effects of antihypertensive therapy in the diabetic rat.
    Kidney international, 1989, Volume: 36, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetic Nephropathies; Drug Administra

1989
Short and long term effects of antihypertensive therapy in the diabetic rat.
    Kidney international, 1989, Volume: 36, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetic Nephropathies; Drug Administra

1989
Short and long term effects of antihypertensive therapy in the diabetic rat.
    Kidney international, 1989, Volume: 36, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetic Nephropathies; Drug Administra

1989
Short and long term effects of antihypertensive therapy in the diabetic rat.
    Kidney international, 1989, Volume: 36, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetic Nephropathies; Drug Administra

1989
Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Glomerular Filtration Rate; Hydralazin

1986
Amelioration by antihypertensive therapy in Dahl-salt sensitive rats with immune complex nephritis and hypertension.
    Igaku kenkyu. Acta medica, 1988, Volume: 58, Issue:5

    Topics: Animals; Antigen-Antibody Complex; Creatinine; Hydralazine; Hypertension, Renal; In Vitro Techniques

1988
Dissociation of renin and noradrenaline release in the renal circulation. Studies on patients with renal hypertension.
    Scandinavian journal of urology and nephrology, 1986, Volume: 20, Issue:3

    Topics: Adult; Aged; Diagnosis, Differential; Dihydralazine; Female; Humans; Hydralazine; Hypertension, Rena

1986
Antihypertensive drugs inhibit hypertension-associated aortic DNA synthesis in the rat.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:12

    Topics: Animals; Antihypertensive Agents; Captopril; DNA; Female; Hydralazine; Hypertension; Hypertension, R

1986
Antihypertensive drug therapy prevents cerebral microvascular abnormalities in hypertensive rats.
    Circulation research, 1987, Volume: 60, Issue:2

    Topics: Adaptation, Physiological; Animals; Antihypertensive Agents; Blood Flow Velocity; Cerebrovascular Ci

1987
Glomerular hypertension and injury in desoxycorticosterone-salt rats on antihypertensive therapy.
    Kidney international, 1987, Volume: 31, Issue:3

    Topics: Animals; Blood Pressure; Capillaries; Desoxycorticosterone; Hydralazine; Hydrochlorothiazide; Hypert

1987
[Antihypertensive effects of SA446, hydralazine and the combination on renal hypertensive rats and spontaneously hypertensive rats by long-term treatment].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 87, Issue:2

    Topics: 3-Mercaptopropionic Acid; Animals; Antihypertensive Agents; Body Weight; Diuresis; Drinking; Drug Th

1986
Selection criteria for drug-treated animals in two-kidney, one clip renal hypertension.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:8

    Topics: Animals; Atrophy; Constriction; Hydralazine; Hypertension, Renal; Kidney; Male; Organ Size; Rats; Ra

1986
Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:10

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relation

1986
Nephrotoxic serum nephritis with hypertension: amelioration by antihypertensive therapy.
    Kidney international, 1985, Volume: 28, Issue:2

    Topics: Animals; Antihypertensive Agents; Dietary Proteins; Glomerular Filtration Rate; Hydralazine; Hydroch

1985
[Drug therapy of hypertension].
    Munchener medizinische Wochenschrift (1950), 1965, Dec-10, Volume: 107, Issue:50

    Topics: Antihypertensive Agents; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Hyper

1965
[Principles of hypertension therapy].
    Munchener medizinische Wochenschrift (1950), 1967, Apr-21, Volume: 109, Issue:16

    Topics: Adult; Antihypertensive Agents; Aortic Valve Stenosis; Brain Neoplasms; Cushing Syndrome; Diagnosis,

1967
[Significance of adrenal catecholamines for reflex cardiovascular counterregulation in rats with renal hypertension].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 265, Issue:5

    Topics: 1-Propanol; Adrenal Medulla; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pr

1970
Essential hypertension in adolescents.
    Postgraduate medicine, 1974, Volume: 56, Issue:6

    Topics: Adolescent; Adult; Antihypertensive Agents; Child; Contraceptives, Oral, Synthetic; Diet, Sodium-Res

1974
Aggressive drug therapy in accelerated hypertension.
    The American journal of nursing, 1974, Volume: 74, Issue:12

    Topics: Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Ferr

1974
[Frequency of hematologic side effects in antihypertensive long-term therapy].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Feb-15, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antihypertensive Agents; Arteriosclerosis; Blood C

1973
[Long-term therapy of renal hypertension with various antihypertensive combinations in nephrologic dispensary consultations].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Feb-15, Volume: 28, Issue:4

    Topics: Drug Combinations; Guanethidine; Humans; Hydralazine; Hypertension, Renal; Imidazoles; Long-Term Car

1973
[Apresoline stimulation of renal-vein plasma renin activity in the diagnosis of renovascular hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1972, Volume: 78

    Topics: Adult; Aged; Female; Humans; Hydralazine; Hypertension, Renal; Male; Middle Aged; Renal Veins; Renin

1972
Problems in therapy for the hypertensive patient.
    Geriatrics, 1973, Volume: 28, Issue:3

    Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic

1973
Modification by antihypertensive drugs of reflex circulatory responses induced by vertical tilting or bilateral carotid occlusion.
    European journal of pharmacology, 1973, Volume: 22, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Clonidine; Dibenzylchlorethamine

1973
[Hypertension of renal origin].
    Revue medicale de Liege, 1973, Volume: 28, Issue:13

    Topics: Clonidine; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydralazine; Hypertension, Renal; Ki

1973
[Plasma renin activity in venous renal blood and its stimulation by hydralazine and theophylline (author's transl)].
    Klinische Wochenschrift, 1973, Sep-01, Volume: 51, Issue:17

    Topics: Blood Pressure; Chemoreceptor Cells; Humans; Hydralazine; Hypertension; Hypertension, Renal; Juxtagl

1973
Infantile polycystic disease of the kidneys.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Oct-13, Volume: 47, Issue:40

    Topics: Child, Preschool; Chlorothiazide; Female; Guanethidine; Humans; Hydralazine; Hypertension, Renal; In

1973
[Renin activity in renal vein blood and its stimulation by various drugs].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79

    Topics: Humans; Hydralazine; Hypertension; Hypertension, Renal; Renal Veins; Renin; Theophylline

1973
[Dihydralazin treatment of hypertension during hemodialysis].
    Zeitschrift fur Urologie und Nephrologie, 1973, Volume: 66, Issue:12

    Topics: Humans; Hydralazine; Hypertension, Renal; Injections, Intravenous; Kidney Failure, Chronic; Renal Di

1973
Unilateral operation for bilateral renovascular disease.
    The Journal of urology, 1974, Volume: 111, Issue:3

    Topics: Arteriosclerosis; Endarterectomy; Humans; Hydralazine; Hypertension, Malignant; Hypertension, Renal;

1974
Juvenile hypertension caused by overproduction of renin within a renal segment.
    The Journal of pediatrics, 1974, Volume: 84, Issue:5

    Topics: Child; Humans; Hydralazine; Hyperaldosteronism; Hypertension, Renal; Juxtaglomerular Apparatus; Kidn

1974
Acute transient renin-mediated hypertension in children following urinary diversion.
    Urology, 1974, Volume: 3, Issue:6

    Topics: Acute Disease; Adolescent; Blood Volume; Child; Creatinine; Dermatologic Surgical Procedures; Female

1974
Pharmacologic management of renovascular hypertension.
    JAMA, 1974, Jan-28, Volume: 227, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Blood Pressure Determination; Diuretics; Dru

1974
[What is reliable in the therapy of hypertension?].
    Der Internist, 1970, Volume: 11, Issue:12

    Topics: Arteriosclerosis; Cerebral Hemorrhage; Diet, Reducing; Diet, Sodium-Restricted; Guanethidine; Health

1970
[Treatment of hypertension in renal failure].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Apr-10, Volume: 92, Issue:10

    Topics: Humans; Hydralazine; Hypertension, Renal; Kidney Failure, Chronic; Methyldopa; Water-Electrolyte Bal

1972
Contribution of the central nervous system to the action of several antihypertensive agents (methyldopa, hydralazine and guanethidine).
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:1

    Topics: Acetylcholine; Administration, Oral; Animals; Asphyxia; Blood Pressure; Central Nervous System; Elec

1972
[Chronic kidney failure].
    Naika. Internal medicine, 1971, Volume: 27, Issue:6

    Topics: Adult; Blood Urea Nitrogen; Diet Therapy; Dihydroxyphenylalanine; Humans; Hydralazine; Hypertension,

1971
Comparative effects of currently available antihypertensive agents on spontaneously and renal hypertensive rats.
    The American journal of the medical sciences, 1970, Volume: 259, Issue:4

    Topics: Animals; Antihypertensive Agents; Chlorothiazide; Guanethidine; Hydralazine; Hypertension; Hypertens

1970
[Secondary effects of hypotensive drugs in arterial hypertension of renal origin].
    Medicina interna, 1970, Volume: 22, Issue:7

    Topics: Adult; Antihypertensive Agents; Female; Guanethidine; Humans; Hydralazine; Hypertension, Renal; Kidn

1970
[Influence of a combinated adelphan-esidrix and clonidin therapy on blood pressure and renal function in renal hypertension].
    Deutsche medizinische Wochenschrift (1946), 1971, Aug-27, Volume: 96, Issue:35

    Topics: Adult; Aniline Compounds; Blood Pressure Determination; Blood Urea Nitrogen; Drug Synergism; Female;

1971
Hypertensive crisis.
    Postgraduate medicine, 1971, Volume: 49, Issue:5

    Topics: Administration, Oral; Adolescent; Aged; Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertens

1971
[Clinical picture and therapy of hypertension].
    Munchener medizinische Wochenschrift (1950), 1967, Sep-08, Volume: 109, Issue:36

    Topics: Adult; Aged; Blood Pressure; Diagnosis, Differential; Diet Therapy; Diet, Sodium-Restricted; Drug Sy

1967
Hypertensive retinopathy. Caliber changes in retinal blood vessels following blood-pressure reduction and inhalation of oxygen.
    Circulation, 1968, Volume: 37, Issue:4

    Topics: Adolescent; Adult; Blood Circulation; Female; Humans; Hydralazine; Hypertension, Renal; Male; Middle

1968
[Results of hypotensive treatment in a hospital environment].
    Minerva medica, 1968, May-19, Volume: 59, Issue:40

    Topics: Adult; Aged; Arteriosclerosis; Carbamates; Female; Humans; Hydralazine; Hydrochlorothiazide; Hyperte

1968
Hydralazine and plasma renin activity.
    Archives of internal medicine, 1968, Volume: 122, Issue:5

    Topics: Adolescent; Adult; Blood Pressure; Diagnosis, Differential; Diet, Sodium-Restricted; Female; Heart R

1968
[May medical therapy of arterial hypertension by used in patients with renal failure?].
    La Presse medicale, 1968, Nov-16, Volume: 76, Issue:44

    Topics: Antihypertensive Agents; Diazoxide; Drug Tolerance; Guanethidine; Humans; Hydralazine; Hypertension;

1968
Control of renin release in experimental hypertension.
    Circulation research, 1969, Volume: 24, Issue:5 Suppl

    Topics: Acetylcholine; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Catheterization; Chronic Dise

1969
Hypertension in end-stage renal disease.
    The New England journal of medicine, 1969, May-01, Volume: 280, Issue:18

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Black People; Blood Pressure; Body Weight; Chronic

1969
[Considerations on ambulatory therapy in a group of hypertensive patients].
    Minerva medica, 1969, Jun-27, Volume: 60, Issue:51

    Topics: Adult; Aged; Ambulatory Care; Carbamates; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothia

1969
Post-hydralazine renin release in the diagnosis of renovascular hypertension.
    Annals of surgery, 1969, Volume: 170, Issue:3

    Topics: Adult; Aged; Aortography; Blood Pressure; Female; Humans; Hydralazine; Hypertension, Renal; Kidney;

1969
Clinical rounds from the Massachusetts General Hospital. Childhood hypertension: etiology, investigation and treatment.
    Clinical pediatrics, 1966, Volume: 5, Issue:1

    Topics: Adolescent; Adrenal Gland Neoplasms; Aortic Coarctation; Child; Child, Preschool; Cushing Syndrome;

1966
Chronic hemodialysis in a pre-adolescent.
    Pediatrics, 1966, Volume: 37, Issue:1

    Topics: Adolescent; Child; Diet, Sodium-Restricted; Female; Glomerulonephritis; Hematocrit; Humans; Hydralaz

1966