hydralazine has been researched along with Hypertension, Pregnancy-Induced in 24 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Hypertension, Pregnancy-Induced: A condition in pregnant women with elevated systolic (
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy." | 9.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy." | 9.22 | Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022) |
| "Diazoxide is one of few available agents for treatment of hypertensive emergencies in pregnancy." | 9.12 | A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial. ( Child, A; Gillin, AG; Henderson-Smart, DJ; Hennessy, A; Makris, A; Ogle, RF; Thornton, CE, 2007) |
| "Magnesium sulfate was promptly administered on admission to every woman to prevent seizure." | 5.56 | Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women. ( Chera-Aree, P; Leetheeragul, J; Sampaojarean, U; Surasereewong, S; Tengtrakulcharoen, P; Wataganara, T, 2020) |
| "We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy." | 5.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy." | 5.22 | Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022) |
| "Diazoxide is one of few available agents for treatment of hypertensive emergencies in pregnancy." | 5.12 | A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial. ( Child, A; Gillin, AG; Henderson-Smart, DJ; Hennessy, A; Makris, A; Ogle, RF; Thornton, CE, 2007) |
| "Oral nifedipine, and possibly labetalol and methyldopa, are suitable options for treatment of severe hypertension in pregnancy/postpartum." | 4.90 | Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review. ( Firoz, T; Gordon, R; MacDonell, K; Magee, LA; Payne, BA; Vidler, M; von Dadelszen, P, 2014) |
| " The American College of Obstetricians and Gynecologists recommends that acute-onset, severe hypertension be treated with first line-therapy (intravenous labetalol, intravenous hydralazine or oral nifedipine) within 60 minutes to reduce risk of maternal morbidity and death." | 3.96 | Identification of factors associated with delayed treatment of obstetric hypertensive emergencies. ( Akerman, MB; Elsayad, A; Halpern, TA; Heiselman, CJ; Heo, HJ; Kantorowska, A; Muscat, JC; Sicuranza, GB; Vintzileos, AM, 2020) |
| "To determine whether the incidence of hypotension or adverse fetal heart tracing (FHT) category change differed following antepartum administration of intravenous (IV) labetalol versus hydralazine." | 3.83 | Risks of parenteral antihypertensive therapy for the treatment of severe maternal hypertension are low. ( Aghajanian, P; Greene, N; Kilpatrick, SJ; Rodriguez, M; Sharma, KJ, 2016) |
| "Magnesium sulfate was promptly administered on admission to every woman to prevent seizure." | 1.56 | Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women. ( Chera-Aree, P; Leetheeragul, J; Sampaojarean, U; Surasereewong, S; Tengtrakulcharoen, P; Wataganara, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 15 (62.50) | 24.3611 |
| 2020's | 4 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, HZ | 1 |
| Cheng, Y | 1 |
| Yu, D | 1 |
| Li, JB | 1 |
| Jiang, YF | 1 |
| Zhu, ZN | 1 |
| Antza, C | 1 |
| Dimou, C | 1 |
| Doundoulakis, I | 1 |
| Akrivos, E | 1 |
| Stabouli, S | 1 |
| Haidich, AB | 1 |
| Goulis, DG | 1 |
| Kotsis, V | 1 |
| Kantorowska, A | 1 |
| Heiselman, CJ | 1 |
| Halpern, TA | 1 |
| Akerman, MB | 1 |
| Elsayad, A | 1 |
| Muscat, JC | 1 |
| Sicuranza, GB | 1 |
| Vintzileos, AM | 1 |
| Heo, HJ | 1 |
| Chera-Aree, P | 1 |
| Tengtrakulcharoen, P | 1 |
| Leetheeragul, J | 1 |
| Sampaojarean, U | 1 |
| Surasereewong, S | 1 |
| Wataganara, T | 1 |
| Sharma, KJ | 2 |
| Kilpatrick, SJ | 3 |
| Sharma, C | 1 |
| Soni, A | 1 |
| Gupta, A | 1 |
| Verma, A | 1 |
| Verma, S | 1 |
| Maaløe, N | 1 |
| Andersen, CB | 1 |
| Housseine, N | 1 |
| Meguid, T | 1 |
| Bygbjerg, IC | 1 |
| van Roosmalen, J | 1 |
| Leavitt, K | 1 |
| Običan, S | 1 |
| Yankowitz, J | 1 |
| Arulkumaran, N | 1 |
| Lightstone, L | 1 |
| Homam, H | 1 |
| Moukhah, S | 1 |
| Alizadeh, M | 1 |
| Firoz, T | 1 |
| Magee, LA | 1 |
| MacDonell, K | 1 |
| Payne, BA | 1 |
| Gordon, R | 1 |
| Vidler, M | 1 |
| von Dadelszen, P | 1 |
| Vadhera, RB | 1 |
| Simon, M | 1 |
| Morris, R | 1 |
| Sunesara, I | 1 |
| Darby, M | 1 |
| Novotny, S | 1 |
| Kiprono, L | 1 |
| Bautista, L | 1 |
| Sawardecker, S | 1 |
| Bofill, J | 1 |
| Anderson, B | 1 |
| Martin, JN | 1 |
| Olson-Chen, C | 1 |
| Seligman, NS | 1 |
| Abreo, A | 1 |
| Greene, N | 2 |
| Melsop, K | 1 |
| Peterson, N | 1 |
| Shields, LE | 1 |
| Main, EK | 1 |
| Rodriguez, M | 1 |
| Aghajanian, P | 1 |
| Kawasaki, S | 1 |
| Kako, K | 1 |
| Nagashima, Y | 1 |
| Kanou, A | 1 |
| Ishida, J | 1 |
| Fukamizu, A | 1 |
| Osol, G | 2 |
| Barron, C | 2 |
| Gokina, N | 1 |
| Mandala, M | 2 |
| Ishii, M | 1 |
| Hattori, A | 1 |
| Numaguchi, Y | 1 |
| Ma, X | 1 |
| Nagasaka, T | 1 |
| Tsujimoto, M | 1 |
| Murohara, T | 1 |
| Kobayashi, H | 1 |
| Mizutani, S | 1 |
| Heazell, AE | 1 |
| Mahomoud, S | 1 |
| Pirie, AM | 1 |
| Vigil-De Gracia, P | 1 |
| Ruiz, E | 1 |
| López, JC | 1 |
| de Jaramillo, IA | 1 |
| Vega-Maleck, JC | 1 |
| Pinzón, J | 1 |
| Hennessy, A | 1 |
| Thornton, CE | 1 |
| Makris, A | 1 |
| Ogle, RF | 1 |
| Henderson-Smart, DJ | 1 |
| Gillin, AG | 1 |
| Child, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The PartoMa Project for Saving Lives at Birth - An Intervention Based Study to Strengthen the Quality of Monitoring, Action and Triage During Labour at an East African Referral Hospital[NCT02318420] | 3,087 participants (Actual) | Interventional | 2014-10-01 | Completed | |||
| Use of Sildenafil Citrate in Management of Mild Pre-eclampsia: A Randomized Controlled Trial[NCT03262961] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2016-09-15 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for hydralazine and Hypertension, Pregnancy-Induced
| Article | Year |
|---|---|
Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Hypertension, Pr | 2022 |
The flipside of hydralazine in pregnancy: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Birth Weight; Female; Heart Rate; Humans; Hydralazine; Hypertension; Hypert | 2020 |
Postpartum Hypertension: Etiology, Diagnosis, and Management.
Topics: Antihypertensive Agents; Blood Pressure; Disease Management; Female; Humans; Hydralazine; Hypertensi | 2017 |
Treatment and Prevention of Hypertensive Disorders During Pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Chronic Dis | 2019 |
Severe pre-eclampsia and hypertensive crises.
Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Critical Care; Early Dia | 2013 |
Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review.
Topics: Administration, Oral; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Pregnancy- | 2014 |
Hypertensive emergencies in pregnancy.
Topics: Antihypertensive Agents; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hyperten | 2014 |
Hypertensive Emergencies in Pregnancy.
Topics: Antihypertensive Agents; Cesarean Section; Chronic Disease; Congenital Abnormalities; Emergencies; E | 2016 |
4 trials available for hydralazine and Hypertension, Pregnancy-Induced
| Article | Year |
|---|---|
Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Apgar Score; Double-Blind Method; Emergencies; Female; Humans; Hyd | 2017 |
Impedance cardiography assessed treatment of acute severe pregnancy hypertension: a randomized trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Cardiography, Impedance; Female; Hum | 2016 |
Management of severe hypertension in the postpartum period with intravenous hydralazine or labetalol: a randomized clinical trial.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; H | 2007 |
A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial.
Topics: Adult; Antihypertensive Agents; Cardiotocography; Cesarean Section; Diazoxide; Female; Humans; Hydra | 2007 |
12 other studies available for hydralazine and Hypertension, Pregnancy-Induced
| Article | Year |
|---|---|
Identification of factors associated with delayed treatment of obstetric hypertensive emergencies.
Topics: Administration, Intravenous; Administration, Oral; Adult; After-Hours Care; Antihypertensive Agents; | 2020 |
Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women.
Topics: Administration, Intravenous; Adult; Antihypertensive Agents; Apgar Score; Asian People; Blood Pressu | 2020 |
Effect of locally tailored clinical guidelines on intrapartum management of severe hypertensive disorders at Zanzibar's tertiary hospital (the PartoMa study).
Topics: Anticonvulsants; Antihypertensive Agents; Apgar Score; Delivery, Obstetric; Female; Humans; Hydralaz | 2019 |
Asymptomatic torsion of a gravid uterus.
Topics: Adult; Antihypertensive Agents; Asymptomatic Diseases; Cesarean Section; Female; Humans; Hydralazine | 2013 |
Severe maternal morbidity in a large cohort of women with acute severe intrapartum hypertension.
Topics: Adult; Antihypertensive Agents; California; Female; Humans; Hydralazine; Hypertension, Pregnancy-Ind | 2016 |
Risks of parenteral antihypertensive therapy for the treatment of severe maternal hypertension are low.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension, Pregnancy | 2016 |
Hydralazine is involved in tele-methylhistamine metabolism by inhibiting monoamine oxidase B in pregnancy-associated hypertensive mice.
Topics: Amines; Animals; Antihypertensive Agents; Biocatalysis; Chromatography, High Pressure Liquid; Female | 2017 |
Inhibition of nitric oxide synthases abrogates pregnancy-induced uterine vascular expansive remodeling.
Topics: Animals; Arteries; Blood Pressure; Enzyme Inhibitors; Female; Fertility; Hydralazine; Hypertension, | 2009 |
The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs).
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compoun | 2009 |
Effects of pregnancy, hypertension and nitric oxide inhibition on rat uterine artery myogenic reactivity.
Topics: Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Female; Hydralazine; Hypertensio | 2010 |
Committee Opinion no. 514: emergent therapy for acute-onset, severe hypertension with preeclampsia or eclampsia.
Topics: Algorithms; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Pregnancy-Induced; L | 2011 |
The treatment of severe hypertension in pregnancy: a review of current practice and knowledge in West-Midlands maternity units.
Topics: Antihypertensive Agents; Female; Hospital Units; Humans; Hydralazine; Hypertension, Pregnancy-Induce | 2004 |