hydralazine has been researched along with Hepatolenticular Degeneration in 2 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Slow turnover rates of the metal were demonstrated in seven out of eight patients with active rheumatoid arthritis, in one with hydralazine disease, but not in one arthritic undergoing an impressive, spontaneous remission." | 9.03 | Slow turnover of manganese in active rheumatoid arthritis accelerated by prednisone. ( Borg, DC; Cotzias, GC; Hughes, ER; Papavasiliou, PS; Tang, L, 1968) |
| " Slow turnover rates of the metal were demonstrated in seven out of eight patients with active rheumatoid arthritis, in one with hydralazine disease, but not in one arthritic undergoing an impressive, spontaneous remission." | 5.03 | Slow turnover of manganese in active rheumatoid arthritis accelerated by prednisone. ( Borg, DC; Cotzias, GC; Hughes, ER; Papavasiliou, PS; Tang, L, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thiele, KG | 1 |
| Muehrcke, RC | 1 |
| Berning, H | 1 |
| Cotzias, GC | 1 |
| Papavasiliou, PS | 1 |
| Hughes, ER | 1 |
| Tang, L | 1 |
| Borg, DC | 1 |
1 trial available for hydralazine and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Slow turnover of manganese in active rheumatoid arthritis accelerated by prednisone.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Hepatolenticular Degeneration; Humans; Hydralazine; | 1968 |
1 other study available for hydralazine and Hepatolenticular Degeneration
| Article | Year |
|---|---|
[Kidney diseases caused by drugs].
Topics: Acute Kidney Injury; Adult; Anemia; Arthritis, Rheumatoid; Dextrans; Drug-Related Side Effects and A | 1967 |