hydralazine has been researched along with Glomerulosclerosis, Focal Segmental in 10 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Glomerulosclerosis, Focal Segmental: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One week after disease induction, animals were randomly assigned to chronic glomerulosclerosis, chronic glomerulosclerosis plus Bay 41-2272 (10 mg/kg body weight/day) or chronic glomerulosclerosis plus hydralazine (15 mg/kg body weight/day)." | 3.73 | Stimulation of soluble guanylate cyclase slows progression in anti-thy1-induced chronic glomerulosclerosis. ( Kawachi, H; Krämer, S; Kron, S; Loof, T; Martini, S; Neumayer, HH; Peters, H; Shimizu, F; Wang, Y, 2005) |
| "Renal fibrosis is one of the major complications associated with the development of hypertension." | 1.32 | Regression of renal vascular and glomerular fibrosis: role of angiotensin II receptor antagonism and matrix metalloproteinases. ( Boffa, JJ; Chatziantoniou, C; Dussaule, JC; Lu, Y; Placier, S; Stefanski, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boffa, JJ | 1 |
| Lu, Y | 1 |
| Placier, S | 1 |
| Stefanski, A | 1 |
| Dussaule, JC | 1 |
| Chatziantoniou, C | 1 |
| Griffin, KA | 1 |
| Picken, MM | 1 |
| Bidani, AK | 1 |
| Wang, Y | 1 |
| Krämer, S | 1 |
| Loof, T | 1 |
| Martini, S | 1 |
| Kron, S | 1 |
| Kawachi, H | 1 |
| Shimizu, F | 2 |
| Neumayer, HH | 1 |
| Peters, H | 1 |
| Nagase, M | 1 |
| Shibata, S | 1 |
| Yoshida, S | 1 |
| Nagase, T | 1 |
| Gotoda, T | 1 |
| Fujita, T | 1 |
| Vaziri, ND | 1 |
| Kai, T | 1 |
| Kino, H | 1 |
| Ishikawa, K | 1 |
| Obata, J | 1 |
| Nakamura, T | 1 |
| Takano, H | 1 |
| Naito, A | 1 |
| Kimura, H | 1 |
| Yoshida, Y | 2 |
| Guo, DF | 1 |
| Inagami, T | 1 |
| Almroth, G | 1 |
| Eneström, S | 1 |
| Hed, J | 1 |
| Samuelsson, I | 1 |
| Sjöström, P | 1 |
| Kawamura, T | 1 |
| Ikoma, M | 1 |
| Fogo, A | 1 |
| Ichikawa, I | 1 |
| Raij, L | 1 |
| Chiou, XC | 1 |
| Owens, R | 1 |
| Wrigley, B | 1 |
1 review available for hydralazine and Glomerulosclerosis, Focal Segmental
| Article | Year |
|---|---|
Malignant or accelerated hypertension.
Topics: Blood Coagulation Disorders; Brain Diseases; Diazoxide; Glomerulosclerosis, Focal Segmental; Humans; | 1984 |
9 other studies available for hydralazine and Glomerulosclerosis, Focal Segmental
| Article | Year |
|---|---|
Regression of renal vascular and glomerular fibrosis: role of angiotensin II receptor antagonism and matrix metalloproteinases.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Collagen; Enzyme | 2003 |
Blood pressure lability and glomerulosclerosis after normotensive 5/6 renal mass reduction in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Enalapril; Glomeruloscl | 2004 |
Stimulation of soluble guanylate cyclase slows progression in anti-thy1-induced chronic glomerulosclerosis.
Topics: Animals; Biomarkers; Blood Pressure; Body Weight; Chronic Disease; Disease Progression; Eating; Enzy | 2005 |
Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker.
Topics: Animals; Apoptosis; Biomarkers; Blood Pressure; Eplerenone; Fibrosis; Glomerulosclerosis, Focal Segm | 2006 |
Role of the renin-angiotensin system in cardiac hypertrophy and renal glomerular sclerosis in transgenic hypertensive mice carrying both human renin and angiotensinogen genes.
Topics: Albuminuria; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Drinking; Fibronectins; Gene Ex | 1998 |
Increased gene expression of components of the renin-angiotensin system in glomeruli of genetically hypertensive rats.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biph | 2000 |
Autoantibodies to leucocyte antigens in hydralazine-associated nephritis.
Topics: Antibodies, Antinuclear; Female; Glomerulosclerosis, Focal Segmental; HLA Antigens; Humans; Hydralaz | 1992 |
Effects of antihypertensive drugs on glomerular morphology.
Topics: Animals; Antihypertensive Agents; Enalapril; Glomerulonephritis; Glomerulosclerosis, Focal Segmental | 1989 |
Therapeutic implications of hypertension-induced glomerular injury. Comparison of enalapril and a combination of hydralazine, reserpine, and hydrochlorothiazide in an experimental model.
Topics: Animals; Enalapril; Glomerular Filtration Rate; Glomerular Mesangium; Glomerulonephritis; Glomerulos | 1985 |