Page last updated: 2024-10-28

hydralazine and Genetic Predisposition

hydralazine has been researched along with Genetic Predisposition in 10 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Research Excerpts

ExcerptRelevanceReference
" Stroke-prone spontaneously hypertensive Izumo strain rats were divided into four groups, treated with vehicle, the angiotensin-converting enzyme inhibitor (ACEI) delapril (40 mg/kg per d), the angiotensin receptor antagonist (AT1R-Ant) candesartan cilexetil (1 mg/kg per d), or the vasodilator hydralazine (25 mg/kg per d) from weaning to puberty (3 to 10 wk of age), and then monitored without treatment for 6 mo."3.71Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis. ( Hayashi, M; Nakaya, H; Saruta, T; Sasamura, H, 2001)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (80.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, Y1
Sawalha, AH1
Rame, JE1
Tam, SW1
McNamara, D1
Worcel, M1
Sabolinski, ML1
Wu, AH1
Dries, DL1
Leelahavanichkul, A1
Yan, Q1
Hu, X1
Eisner, C1
Huang, Y1
Chen, R1
Mizel, D1
Zhou, H1
Wright, EC1
Kopp, JB1
Schnermann, J1
Yuen, PS1
Star, RA1
Wassmann, S1
Czech, T1
van Eickels, M1
Fleming, I1
Böhm, M1
Nickenig, G1
Puckrein, G1
Yancy, CW2
Echols, MR1
Hoover, EL1
Sade, RM1
Nakaya, H1
Sasamura, H1
Hayashi, M1
Saruta, T1

Reviews

2 reviews available for hydralazine and Genetic Predisposition

ArticleYear
Drug-induced lupus erythematosus: an update on drugs and mechanisms.
    Current opinion in rheumatology, 2018, Volume: 30, Issue:5

    Topics: Autoimmunity; Genetic Predisposition to Disease; Humans; Hydralazine; Immunologic Factors; Lupus Ery

2018
Isosorbide dinitrate-hydralazine combination therapy in African Americans with heart failure.
    Vascular health and risk management, 2006, Volume: 2, Issue:4

    Topics: Black or African American; Disease Progression; Drug Combinations; Endothelium, Vascular; Genetic Pr

2006

Other Studies

8 other studies available for hydralazine and Genetic Predisposition

ArticleYear
Dysfunctional corin i555(p568) allele is associated with impaired brain natriuretic peptide processing and adverse outcomes in blacks with systolic heart failure: results from the Genetic Risk Assessment in Heart Failure substudy.
    Circulation. Heart failure, 2009, Volume: 2, Issue:6

    Topics: Black or African American; Cardiovascular Agents; Double-Blind Method; Drug Combinations; Female; Ge

2009
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
    Kidney international, 2010, Volume: 78, Issue:11

    Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertens

2010
Inhibition of diet-induced atherosclerosis and endothelial dysfunction in apolipoprotein E/angiotensin II type 1A receptor double-knockout mice.
    Circulation, 2004, Nov-09, Volume: 110, Issue:19

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Diseases; Apolipoproteins E; Arterioscleros

2004
Illuminating BiDil.
    Nature biotechnology, 2005, Volume: 23, Issue:8

    Topics: Black or African American; Drug Approval; Drug Combinations; Genetic Predisposition to Disease; Hear

2005
BiDil's impact.
    Nature biotechnology, 2005, Volume: 23, Issue:11

    Topics: Black or African American; Drug Approval; Drug Combinations; Genetic Predisposition to Disease; Hear

2005
There is no scientific rationale for race-based research.
    Journal of the National Medical Association, 2007, Volume: 99, Issue:6

    Topics: Biomarkers; Biomedical Research; Black or African American; Clinical Trials as Topic; Drug Combinati

2007
What's right (and wrong) with racially stratified research and therapies.
    Journal of the National Medical Association, 2007, Volume: 99, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Biomedical Research; Black or African American

2007
Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angioten

2001