hydralazine has been researched along with Endomyocardial Fibrosis in 5 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Endomyocardial Fibrosis: A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We evaluated the effects of combining an angiotensin II type 1 (AT1) receptor blocker (ARB, valsartan) and a NEPI (CGS 25354) in comparison with a dual ACEI/NEPI (CGS 30440) in stroke-prone spontaneously hypertensive rats (SHRSP)." | 3.74 | Effects of combined AT1 receptor antagonist/NEP inhibitor on vascular remodeling and cardiac fibrosis in SHRSP. ( Amiri, F; Brassard, P; Iglarz, M; Javeshghani, DM; Pu, Q; Schiffrin, EL; Webb, RL, 2008) |
| "Azelnidipine suppressed cardiac hypertrophy, fibrosis, NADPH oxidase and superoxide in spSHRs more potently than amlodipine, and was associated with lower heart rates than amlodipine." | 3.73 | Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis. ( Ito, T; Kataoka, K; Kim-Mitsuyama, S; Lai, ZF; Ogawa, H; Tanaka, T; Tokutomi, Y; Yamamoto, E; Yamashita, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seymour, EM | 1 |
| Singer, AA | 1 |
| Bennink, MR | 1 |
| Parikh, RV | 1 |
| Kirakosyan, A | 1 |
| Kaufman, PB | 1 |
| Bolling, SF | 1 |
| Yamamoto, E | 1 |
| Lai, ZF | 1 |
| Yamashita, T | 1 |
| Tanaka, T | 1 |
| Kataoka, K | 1 |
| Tokutomi, Y | 1 |
| Ito, T | 1 |
| Ogawa, H | 1 |
| Kim-Mitsuyama, S | 1 |
| Pu, Q | 1 |
| Brassard, P | 1 |
| Javeshghani, DM | 1 |
| Iglarz, M | 1 |
| Webb, RL | 1 |
| Amiri, F | 1 |
| Schiffrin, EL | 1 |
| Li, D | 1 |
| Shinagawa, K | 1 |
| Pang, L | 1 |
| Leung, TK | 1 |
| Cardin, S | 1 |
| Wang, Z | 1 |
| Nattel, S | 1 |
| Lalich, JJ | 1 |
| Paik, WC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| GRAPe Seed Extract and Ventriculovascular Investigation in Normal Ejection-Fraction Heart Failure[NCT01185067] | Phase 1 | 15 participants (Actual) | Interventional | 2010-10-31 | Completed | ||
| Cardioprotective Effects of Freeze Dried Grape Powder Supplementation on Blood Pressure and Plasma Lipids/Lipoproteins: A Pilot Study[NCT03659695] | 20 participants (Anticipated) | Interventional | 2020-01-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for hydralazine and Endomyocardial Fibrosis
| Article | Year |
|---|---|
Chronic intake of a phytochemical-enriched diet reduces cardiac fibrosis and diastolic dysfunction caused by prolonged salt-sensitive hypertension.
Topics: Analysis of Variance; Animals; Diet; Endomyocardial Fibrosis; Fruit; Heart Failure, Diastolic; Hydra | 2008 |
Chronic intake of a phytochemical-enriched diet reduces cardiac fibrosis and diastolic dysfunction caused by prolonged salt-sensitive hypertension.
Topics: Analysis of Variance; Animals; Diet; Endomyocardial Fibrosis; Fruit; Heart Failure, Diastolic; Hydra | 2008 |
Chronic intake of a phytochemical-enriched diet reduces cardiac fibrosis and diastolic dysfunction caused by prolonged salt-sensitive hypertension.
Topics: Analysis of Variance; Animals; Diet; Endomyocardial Fibrosis; Fruit; Heart Failure, Diastolic; Hydra | 2008 |
Chronic intake of a phytochemical-enriched diet reduces cardiac fibrosis and diastolic dysfunction caused by prolonged salt-sensitive hypertension.
Topics: Analysis of Variance; Animals; Diet; Endomyocardial Fibrosis; Fruit; Heart Failure, Diastolic; Hydra | 2008 |
Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis.
Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Cardiomegaly; Dihydropyridines; Endomyocardial Fibros | 2006 |
Effects of combined AT1 receptor antagonist/NEP inhibitor on vascular remodeling and cardiac fibrosis in SHRSP.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Drug Ther | 2008 |
Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Fibrillation; Dogs; Electr | 2001 |
Influence of hydralazine consumption on allylamine induced myocardial fibrosis and hypertrophy in rats.
Topics: Allyl Compounds; Amines; Animals; Aorta, Thoracic; Cardiomegaly; Coronary Vessels; Diet; Endomyocard | 1974 |