Page last updated: 2024-10-28

hydralazine and Cutis Elastica

hydralazine has been researched along with Cutis Elastica in 3 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Research Excerpts

ExcerptRelevanceReference
"Hydralazine treatment, with or without ascorbate, severely decreased the alpha 1(I) collagen mRNAs in fibroblasts from both AT750 and the normal donor; total collagen synthesis was similarly reduced."5.29The mRNA and the activity of lysyl hydroxylase are up-regulated by the administration of ascorbate and hydralazine to human skin fibroblasts from a patient with Ehlers-Danlos syndrome type VI. ( Marshall, MK; Murad, S; Pinnell, SR; Walker, LC; Yeowell, HN, 1995)
"Hydralazine treatment, with or without ascorbate, severely decreased the alpha 1(I) collagen mRNAs in fibroblasts from both AT750 and the normal donor; total collagen synthesis was similarly reduced."1.29The mRNA and the activity of lysyl hydroxylase are up-regulated by the administration of ascorbate and hydralazine to human skin fibroblasts from a patient with Ehlers-Danlos syndrome type VI. ( Marshall, MK; Murad, S; Pinnell, SR; Walker, LC; Yeowell, HN, 1995)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yeowell, HN2
Walker, LC2
Marshall, MK1
Murad, S2
Pinnell, SR2
Gallop, PM1
Paz, MA1

Reviews

1 review available for hydralazine and Cutis Elastica

ArticleYear
Posttranslational protein modifications, with special attention to collagen and elastin.
    Physiological reviews, 1975, Volume: 55, Issue:3

    Topics: Amino Acid Sequence; Animals; Antibody Specificity; Ascorbic Acid; Collagen; Connective Tissue; Copp

1975

Other Studies

2 other studies available for hydralazine and Cutis Elastica

ArticleYear
The mRNA and the activity of lysyl hydroxylase are up-regulated by the administration of ascorbate and hydralazine to human skin fibroblasts from a patient with Ehlers-Danlos syndrome type VI.
    Archives of biochemistry and biophysics, 1995, Aug-20, Volume: 321, Issue:2

    Topics: Ascorbic Acid; Blotting, Northern; Cell Line; Cells, Cultured; Collagen; Ehlers-Danlos Syndrome; Fib

1995
A common duplication in the lysyl hydroxylase gene of patients with Ehlers Danlos syndrome type VI results in preferential stimulation of lysyl hydroxylase activity and mRNA by hydralazine.
    Archives of biochemistry and biophysics, 1997, Nov-01, Volume: 347, Issue:1

    Topics: 2,2'-Dipyridyl; Ascorbic Acid; Blotting, Northern; Ehlers-Danlos Syndrome; Enzyme Activation; Fibrob

1997