hydralazine has been researched along with Coronary Heart Disease in 49 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fifty patients with symptoms due to chronic heart failure despite diuretic therapy were randomised to receive additional treatment with either hydralazine or captopril." | 9.07 | Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine. ( Brooks, NH; Lawrence, GP; Schofield, PM; Testa, HJ; Ward, C, 1991) |
| "A 14-year-old patient with pheochromocytoma is described in whom myocardial ischaemia occurred following hydralazine administration." | 7.67 | Pheochromocytoma and hydralazine-induced myocardial ischaemia in a 14-year-old boy. ( Friedman, E; Katznelson, D; Mandel, M; Sack, J, 1986) |
| "Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates." | 7.66 | Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978) |
| " Fifty patients with symptoms due to chronic heart failure despite diuretic therapy were randomised to receive additional treatment with either hydralazine or captopril." | 5.07 | Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine. ( Brooks, NH; Lawrence, GP; Schofield, PM; Testa, HJ; Ward, C, 1991) |
| "Organic nitrates still are one of the most important drug classes used in the treatment of an acute coronary syndrome and stable coronary artery disease as well as acute and chronic congestive heart failure." | 4.84 | [Recent findings on nitrates: their action, bioactivation and development of tolerance]. ( Münzel, T, 2008) |
| "Although hydralazine is a commonly prescribed antihypertensive agent, reports of acute human poisoning are uncommon." | 3.68 | Acute hydralazine overdose: marked ECG abnormalities in a young adult. ( Ferguson, DB; Smith, BA, 1992) |
| "A 14-year-old patient with pheochromocytoma is described in whom myocardial ischaemia occurred following hydralazine administration." | 3.67 | Pheochromocytoma and hydralazine-induced myocardial ischaemia in a 14-year-old boy. ( Friedman, E; Katznelson, D; Mandel, M; Sack, J, 1986) |
| "Although hydralazine provokes myocardial ischemic events in hypertensive patients not in heart failure by producing reflex tachycardia, the frequency of and mechanisms underlying ischemic events when this drug is administered as a vasodilator agent to patients with heart failure is unknown." | 3.66 | Provocation of myocardial ischemic events during initiation of vasodilator therapy for severe chronic heart failure. Clinical and hemodynamic evaluation of 52 consecutive patients with ischemic cardiomyopathy. ( Gorlin, R; Medina, N; Meller, J; Packer, M; Yushak, M, 1981) |
| "A regimen consisting of chlorthalidone, hydralazine and propranolol would be useful in some hypertensive patients with coronary artery disease or aortic dissection if it could be shown that reflex cardiac stimulation induced by hydralazine is completely neutralized by propranolol." | 3.66 | Echocardiographic assessment of the effect of an antihypertensive regimen on left ventricular performance. ( Belasco, RN; Moyer, JP; Pittman, AW; Woods, JW, 1979) |
| "Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates." | 3.66 | Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978) |
| "Heart failure is a substantial cause of increased morbidity and mortality in the African-American population, with poorer prognosis versus white patients." | 2.41 | Contemporary treatment of heart failure: is there adequate evidence to support a unique strategy for African-Americans? Con position. ( Ferdinand, DP; Ferdinand, KC; Serrano, CC, 2002) |
| "With hydralazine there were parallel changes in the rate-pressure product and MVO2." | 1.26 | Vasodilators in heart failure secondary to coronary artery disease. ( Chatterjee, K; Parmley, WW; Rouleau, JL, 1982) |
| "The treatment of both hyperlipidemia and hypertension appeared to be more effective than the treatment of hyperlipidemia, alone." | 1.26 | Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta. ( Hollander, W; Kirkpatrick, B; Madoff, I; Paddock, J, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (81.63) | 18.7374 |
| 1990's | 6 (12.24) | 18.2507 |
| 2000's | 3 (6.12) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Münzel, T | 1 |
| Ferdinand, KC | 1 |
| Serrano, CC | 1 |
| Ferdinand, DP | 1 |
| HUEGIN, W | 1 |
| SANCHETTI, P | 1 |
| FAVERO, S | 1 |
| BRUSCA, A | 1 |
| Moran, AE | 1 |
| Cooper, RS | 1 |
| Menard, J | 1 |
| Michel, JB | 1 |
| Dussaule, JC | 1 |
| Alhenc-Gelas, F | 1 |
| Corvol, P | 1 |
| Miettinen, TA | 1 |
| Vanhanen, H | 1 |
| Huttunen, JK | 1 |
| Naukkarinen, V | 1 |
| Mattila, S | 1 |
| Strandberg, T | 1 |
| Kumlin, T | 1 |
| Shevchenko, VA | 1 |
| Schapel, GJ | 1 |
| Ram, CV | 1 |
| Bolte, HD | 1 |
| Reifart, N | 1 |
| Kaltenbach, M | 1 |
| Bussmann, WD | 1 |
| Klepzig, M | 1 |
| Kment, A | 1 |
| Kleinhans, E | 1 |
| Büll, U | 1 |
| Strauer, BE | 2 |
| Chatterjee, K | 3 |
| Rouleau, JL | 3 |
| Benge, W | 1 |
| Parmley, WW | 2 |
| Hiramatsu, B | 1 |
| Packer, M | 1 |
| Meller, J | 1 |
| Medina, N | 1 |
| Yushak, M | 1 |
| Gorlin, R | 1 |
| Hindman, MC | 1 |
| Slosky, DA | 1 |
| Peter, RH | 1 |
| Newman, GE | 1 |
| Jones, RH | 1 |
| Wallace, AG | 1 |
| Wilhelmsen, L | 1 |
| Berglund, G | 1 |
| Sannerstedt, R | 1 |
| Hansson, L | 1 |
| Andersson, O | 1 |
| Sievertsson, R | 1 |
| Wikstrand, J | 1 |
| Moyer, JP | 1 |
| Pittman, AW | 1 |
| Belasco, RN | 1 |
| Woods, JW | 1 |
| Laslett, LJ | 1 |
| DeMaria, AN | 1 |
| Amsterdam, EA | 1 |
| Mason, DT | 1 |
| Hollander, W | 1 |
| Madoff, I | 1 |
| Paddock, J | 1 |
| Kirkpatrick, B | 1 |
| Cohen, JD | 1 |
| Smith, BA | 1 |
| Ferguson, DB | 1 |
| Priebe, HJ | 1 |
| Morita, S | 1 |
| Takahashi, H | 1 |
| Kono, M | 1 |
| Uno, Y | 1 |
| Ozawa, M | 1 |
| Sato, T | 1 |
| Schofield, PM | 1 |
| Brooks, NH | 1 |
| Lawrence, GP | 1 |
| Testa, HJ | 1 |
| Ward, C | 1 |
| Moulds, RF | 1 |
| Langnickel, R | 1 |
| Bluth, R | 1 |
| Löllgen, H | 1 |
| Schmidt, A | 1 |
| Upmeyer, HJ | 1 |
| Ktsoeva, TV | 1 |
| Sivkov, SI | 1 |
| Lesniak, EA | 1 |
| Khomenko, VL | 1 |
| Friedman, E | 1 |
| Mandel, M | 1 |
| Katznelson, D | 1 |
| Sack, J | 1 |
| Buchborn, E | 1 |
| Holzgreve, H | 1 |
| Kilcoyne, MM | 1 |
| Thomson, GE | 1 |
| Branche, G | 1 |
| Williams, M | 1 |
| Garnier, C | 1 |
| Chiles, B | 1 |
| Soland, T | 1 |
| Freis, ED | 1 |
| Arnold, OH | 1 |
| Amery, A | 1 |
| Fagard, R | 1 |
| Misotten, A | 1 |
| Slany, J | 1 |
| Koch-Weser, J | 1 |
| Chasis, H | 1 |
| Laidlaw, JC | 1 |
| Vrcelj, S | 1 |
| Vidt, DG | 1 |
| Tretenhahn, W | 1 |
10 reviews available for hydralazine and Coronary Heart Disease
| Article | Year |
|---|---|
[Recent findings on nitrates: their action, bioactivation and development of tolerance].
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Coronary Disease; Drug Tolerance; End | 2008 |
Contemporary treatment of heart failure: is there adequate evidence to support a unique strategy for African-Americans? Con position.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blac | 2002 |
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C | 1963 |
[THERAPY OF ESSENTIAL HYPERTENSION].
Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Coronary Disease; Diazoxide; Diet; Dihydr | 1963 |
[Treatment of heart failure in ischemic heart disease with beta-adrenostimulators and peripheral vasodilators].
Topics: Adrenergic beta-Agonists; Captopril; Cardiotonic Agents; Coronary Disease; Dobutamine; Dopamine; Hea | 1983 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
[Treatment of heart failure with vasodilators].
Topics: Captopril; Cardiomegaly; Cardiotonic Agents; Coronary Disease; Heart Failure; Heart Function Tests; | 1980 |
Effectiveness of drug therapy in hypertension: present status. A review.
Topics: Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Eye Diseases; Ganglionic Block | 1971 |
[Cardiac complications in hypertension].
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Diseas | 1972 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Coronary D | 1974 |
7 trials available for hydralazine and Coronary Heart Disease
| Article | Year |
|---|---|
Loss of effectiveness of dihydralazine in the long-term treatment of chronic heart failure.
Topics: Adult; Aged; Cardiac Output; Chronic Disease; Coronary Circulation; Coronary Disease; Dihydralazine; | 1984 |
Alterations in left ventricular function and coronary hemodynamics with captopril, hydralazine and prazosin in chronic ischemic heart failure: a comparative study.
Topics: Aged; Captopril; Coronary Disease; Dose-Response Relationship, Drug; Heart Failure; Hemodynamics; Hu | 1982 |
Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine.
Topics: Adult; Aged; Captopril; Cardiomyopathy, Dilated; Chronic Disease; Coronary Disease; Exercise Test; F | 1991 |
[Double-blind comparison of fixed combination preparations of a beta blocker and a diuretic and beta blocker, a diuretic and hydralazine in patients with coronary heart disease and arterial hypertension].
Topics: Adrenergic beta-Antagonists; Aged; Amiloride; Clinical Trials as Topic; Coronary Disease; Double-Bli | 1986 |
Effects of treatment on morbidity in hypertension. 3. Influence of age, diastolic pressure, and prior cardiovascular disease; further analysis of side effects.
Topics: Adult; Age Factors; Aged; Aneurysm; Atrial Fibrillation; Blood Glucose; Blood Pressure; Cerebrovascu | 1972 |
Appraisal of antihypertensive drug therapy.
Topics: Antihypertensive Agents; Arteriosclerosis; Clinical Trials as Topic; Coronary Disease; Diabetes Comp | 1974 |
Hypertension: a challenge in preventive medicine.
Topics: Age Factors; Attitude to Health; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disea | 1974 |
32 other studies available for hydralazine and Coronary Heart Disease
| Article | Year |
|---|---|
[CLINICAL STUDY OF A NEW COMPLEX HYPOTENSIVE DRUG COMBINATION].
Topics: Antihypertensive Agents; Arteriosclerosis; Carbamates; Cerebrovascular Disorders; Coronary Disease; | 1963 |
Isosorbide dinitrate and hydralazine in blacks with heart failure.
Topics: Black People; Coronary Disease; Drug Therapy, Combination; Heart Failure; Humans; Hydralazine; Hyper | 2005 |
Potentials and limitations of angiotensin converting enzyme inhibition in the treatment of hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Clonidine; | 1984 |
HDL cholesterol and beta-adrenoceptor blocking agents in a 5 year multifactorial primary prevention trial.
Topics: Adrenergic beta-Antagonists; Cholesterol; Cholesterol, HDL; Coronary Disease; Diuretics; Humans; Hyd | 1982 |
Skin rash and hydralazine.
Topics: Aged; Coronary Disease; Drug Eruptions; Humans; Hydralazine; Male | 1984 |
[Myocardial 201-thallium uptake after hydralazine in coronary disease].
Topics: Coronary Circulation; Coronary Disease; Humans; Hydralazine; Hypertension; Male; Myocardium; Radiois | 1983 |
Hemodynamic and metabolic effects of vasodilators, nitrates, hydralazine, prazosin and captopril in chronic ischemic heart failure.
Topics: Captopril; Coronary Disease; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Lactates; Myoc | 1981 |
Vasodilators in heart failure secondary to coronary artery disease.
Topics: Cardiac Output; Coronary Disease; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Myocardi | 1982 |
Provocation of myocardial ischemic events during initiation of vasodilator therapy for severe chronic heart failure. Clinical and hemodynamic evaluation of 52 consecutive patients with ischemic cardiomyopathy.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Disease; Female; Heart F | 1981 |
Rest and exercise hemodynamic effects of oral hydralazine in patients with coronary artery disease and left ventricular dysfunction.
Topics: Aged; Blood Pressure; Cardiac Output; Cardiac Output, Low; Coronary Disease; Female; Hemodynamics; H | 1980 |
Effect of treatment of hypertension in the primary preventive trial, Göteborg, Sweden.
Topics: Adrenergic beta-Antagonists; Bethanidine; Cardiovascular Diseases; Cerebrovascular Disorders; Corona | 1979 |
Echocardiographic assessment of the effect of an antihypertensive regimen on left ventricular performance.
Topics: Adult; Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Chlorthalidone; Coronary Disease | 1979 |
Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy.
Topics: Aged; Coronary Disease; Digitalis Glycosides; Female; Furosemide; Heart Failure; Humans; Hydralazine | 1978 |
Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta.
Topics: Animals; Aortic Coarctation; Arteriosclerosis; Blood Pressure; Body Weight; Cholesterol, Dietary; Co | 1976 |
Abnormal electrocardiograms and cardiovascular risk: role of silent myocardial ischemia. Evidence from MRFIT.
Topics: Adult; Antihypertensive Agents; Chlorthalidone; Cholesterol, Dietary; Coronary Disease; Electrocardi | 1992 |
Acute hydralazine overdose: marked ECG abnormalities in a young adult.
Topics: Adult; Alcoholic Intoxication; Antacids; Cardiopulmonary Resuscitation; Charcoal; Citrates; Citric A | 1992 |
Myocardial ischemia during vasodilator therapy in a canine model of pulmonary hypertension and coronary insufficiency.
Topics: Alprostadil; Animals; Coronary Disease; Coronary Vessels; Dogs; Hemodynamics; Hydralazine; Hypertens | 1992 |
Effects of hydralazine and prostaglandin E1 on regional myocardial function in the ischemic canine heart.
Topics: Alprostadil; Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Hydralazine; Male; Regio | 1991 |
Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure.
Topics: Adult; Animals; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary | 1990 |
Clinical pharmacology of vasodilator drugs.
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Coronary Disease; Humans; Hydralazine; Hyper | 1985 |
[Pharmacokinetic properties and indications for modern vasodilators. 1. Pharmacodynamic properties of vasodilators].
Topics: Adrenergic alpha-Antagonists; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Arrhythmias | 1985 |
[Role of vasodilator agents in the complex treatment of circulatory insufficiency in patients with ischemic heart disease].
Topics: Aged; Blood Pressure; Blood Volume; Cardiomyopathy, Dilated; Coronary Disease; Delayed-Action Prepar | 1986 |
[The effect of apressin on the results of the Valsalva test in ischemic heart disease].
Topics: Aged; Coronary Disease; Female; Heart Failure; Humans; Hydralazine; Male; Middle Aged; Valsalva Mane | 1988 |
Pheochromocytoma and hydralazine-induced myocardial ischaemia in a 14-year-old boy.
Topics: Adolescent; Adrenal Gland Neoplasms; Cardiomyopathy, Hypertrophic; Coronary Disease; Humans; Hydrala | 1986 |
Results of treatment of hypertension.
Topics: Acute Kidney Injury; Antihypertensive Agents; Cardiovascular Diseases; Coronary Disease; Female; Hum | 1971 |
[Differential diagnosis and pharmacotherapy of hypertension (author's transl)].
Topics: Arteriosclerosis; Coronary Disease; Diagnosis, Differential; Diuretics; Electrocardiography; Guaneth | 1974 |
Characteristics of hypertension in the black population.
Topics: Adult; Angiotensin II; Animals; Black or African American; Cardiomegaly; Cerebrovascular Disorders; | 1974 |
[Therapy of arterial hypertension. Results, possibilities, methods].
Topics: Adrenergic beta-Antagonists; Cerebrovascular Circulation; Coronary Disease; Diet; Diuretics; Electri | 1970 |
[Indications of antihypertensive treatment in non-malignant hypertension].
Topics: Antihypertensive Agents; Aortic Aneurysm; Benzothiadiazines; Cerebrovascular Disorders; Coronary Dis | 1974 |
[Arterial hypertension in elderly persons].
Topics: Aged; Central Nervous System Diseases; Coronary Disease; Humans; Hydralazine; Hypertension; Kidney D | 1972 |
An approach to the medical treatment of hypertension in the aged.
Topics: Age Factors; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Diuretics; | 1969 |
[The treatment of hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Child; Child, Preschool; Coronar | 1966 |